TWAS hub - HNRNPL

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.088	0.0390	0.0095	0.001	0.016	0.032	0.022	0.000	2.6e-01	4.6e-03	7.8e-05	8.4e-04	3.1e-01
2	YFS	Blood	0.487	0.0375	0.0000	0.197	0.276	0.306	0.291	0.284	3.1e-62	7.7e-91	1.7e-102	2.3e-96	1.1e-93

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Pain all over the body in last month	5.5	5.9	7.5	-2.1	2.7
Blood clot in the leg (DVT)	5.0	6.5	11.0	-3.3	1.4
Deep venous thrombosis (DVT) (self-reported)	4.5	5.8	9.9	-3.1	1.3
Prospective memory result	3.4	4.2	5.1	1.8	-2.3
Medication: Cholesterol lowering	3.2	5.0	9.9	3.1	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	3.1	4.0	6.6	-1.2	2.6
Migraine (self-reported)	2.9	3.6	4.2	-1.7	2.0
Ever depressed for a whole week	2.8	3.5	6.1	-1.0	2.5
Depression (self-reported)	2.7	3.2	4.8	-1.3	2.2
Commuting to job workplace: Car/motor vehicle	2.6	3.0	3.0	-1.7	1.7
Fractured/broken bones in last 5 years	2.6	3.3	5.4	-1.1	2.3
Major Depression (MDD)	2.5	3.0	5.5	-2.3	0.7
Osteoporosis (self-reported)	2.5	3.1	6.2	0.0	-2.5
Rheumatoid Arthritis	2.3	3.1	3.5	1.7	-1.9
Age started oral contraceptive pill	2.3	2.8	5.6	-2.4	0.2
Sensitivity / hurt feelings	2.2	3.7	7.4	2.7	-0.2
Qualifications: NVQ or HND or HNC or equivalent	2.2	2.7	5.1	2.3	0.4
Qualifications: CSEs or equivalent	2.1	2.8	3.5	1.9	-1.4
Schizophrenia vs Biploar Disorder	2.0	2.6	3.2	-1.4	1.8
Schizophrenia (2014)	2.0	4.4	7.3	-2.7	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.1	3.5	-1.7	1.9
Myopia	2.0	3.0	5.0	1.0	-2.2
Blood Platelet Count	1.9	21.5	35.5	6.0	-2.8
Angina	1.9	2.5	3.8	1.1	-1.9
Irritability	1.9	3.3	3.7	1.9	1.7
Schizophrenia (2018)	1.8	3.6	7.2	-2.7	0.3
High blood pressure (mother)	1.8	2.5	3.9	-1.0	2.0
Pulse rate	1.8	3.1	5.9	2.4	-0.6
Pain type(s) experienced in last month: Hip pain	1.8	2.3	3.2	-1.8	1.2
Age at First Birth	1.6	2.3	3.7	1.0	-1.9
Length of working week for main job	1.6	1.7	2.6	-0.9	1.6
Worry too long after embarrassment	1.6	2.7	5.4	2.3	-0.2
Commuting to job workplace: Public transport	1.6	2.0	3.6	0.5	-1.9
Bipolar Disorder or Schizophrenia	1.5	3.6	7.3	-2.7	-0.1
Supplements: Zinc	1.5	1.6	2.2	-1.5	1.0
Neuroticism score	1.5	3.1	5.5	2.4	0.8
Angina (self-reported)	1.5	2.0	3.1	0.9	-1.8
Long-standing illness, disability or infirmity	1.5	2.3	2.6	-1.4	1.6
Ever had hysterectomy (womb removed)	1.4	1.6	2.9	-1.7	0.5
Age when periods started (menarche)	1.4	3.4	5.5	-1.2	2.3
Had other major operations	1.4	1.7	3.1	-1.8	0.6
Medication: Lansoprazole	1.4	1.6	2.4	-1.6	0.9
Ever unenthusiastic/disinterested for a whole week	1.3	1.5	3.0	-0.3	1.7
Birth weight	1.3	2.7	3.3	1.8	-1.5
Mood swings	1.3	2.3	4.2	2.1	0.7
Wears glasses or contact lenses	1.3	1.5	2.7	0.5	-1.6
Medication: Lisinopril	1.3	1.7	2.9	1.7	-0.7
Supplements: Glucosamine	1.2	1.6	2.9	0.5	-1.7
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	1.9	-1.4	1.4
Had menopause	1.2	1.5	3.0	-1.7	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	5.3	-2.3	-0.2
Medication: Simvastatin	1.2	1.8	3.5	1.9	-0.1
Medication for cholesterol, blood pressure or diabetes	1.2	1.9	3.7	-1.9	0.4
Pulse rate, automated reading	1.2	3.9	7.7	2.8	-0.4
Medication: Gliclazide	1.2	1.4	2.6	-0.5	1.6
Ever used hormone-replacement therapy (HRT)	1.1	1.3	2.7	-0.1	-1.6
Medication: Atenolol	1.1	1.4	2.8	1.7	-0.1
Falls in the last year	1.1	1.5	2.7	-0.6	1.6
Average weekly red wine intake	1.1	1.6	3.2	-1.8	0.3
Commuting to job workplace: Walk	1.1	1.2	2.2	0.4	1.5
Basal cell carcinoma (self-reported)	1.1	1.3	2.0	-0.7	-1.4
Depression (Nagel 2018)	1.0	1.5	2.0	-1.4	1.0
Alzheimer’s Disease (in father)	1.0	1.1	2.0	-1.4	0.4
Mean Putamen Volume	1.0	1.1	1.6	-1.3	-0.8
Neuroticism	1.0	2.4	3.8	1.0	2.0
Hayfever, allergic rhinitis or eczema	1.0	2.1	3.2	1.0	-1.8
Trunk fat mass	1.0	4.4	8.2	-2.9	0.8
Waist circumference	1.0	3.6	7.1	-2.7	0.4
Alcohol usually taken with meals	1.0	1.5	2.7	0.6	-1.6
Hip circumference	1.0	4.4	8.1	-2.8	0.8
Eye problems/disorders: None of the above	1.0	1.2	2.1	1.5	-0.5
Mean time to correctly identify matches	1.0	1.8	2.1	-1.2	-1.5
Whole body fat mass	1.0	4.0	7.5	-2.7	0.7
Qualifications: nursing, teaching	1.0	1.6	2.8	-0.6	1.7
Medication: Paracetamol	1.0	1.6	3.2	-0.2	1.8
Ever had prostate specific antigen (PSA) test	1.0	1.1	1.1	-1.0	1.1
Allergy or Eczema	0.9	2.5	2.5	1.6	-1.6
Average weekly spirits intake	0.9	1.1	2.2	-1.5	0.1
Trunk fat percentage	0.9	3.6	5.9	-2.4	1.1
Illnesses of mother	0.9	1.1	2.2	0.3	-1.5
Arm fat mass (right)	0.9	3.8	6.8	-2.6	0.8
Body fat percentage	0.9	3.5	5.4	-2.3	1.2
Shortness of breath walking on level ground	0.9	1.1	1.9	-1.4	0.6
Emphysema/chronic bronchitis	0.9	1.0	1.7	-1.3	0.5
Illnesses of father: None of the above (group 1)	0.9	1.1	1.6	1.3	-0.8
Arm fat mass (left)	0.9	3.6	6.9	-2.6	0.7
Tinnitus: Yes, now most or all of the time	0.9	1.1	1.5	0.8	-1.2
Number of operations (self-reported)	0.9	1.3	1.9	-1.4	0.8
Average weekly beer plus cider intake	0.9	1.3	2.6	-1.6	0.1
Depressed Affect (Nagel 2018)	0.8	1.7	3.1	0.6	1.8
Triglycerides	0.8	1.3	1.7	1.3	0.9
Systolic Blood Pressure	0.8	3.8	7.5	2.7	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.7	3.4	-1.8	-0.3
Fluid intelligence score	0.8	1.7	3.4	1.8	-0.2
Weight	0.8	4.0	8.1	-2.8	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	1.3	1.1	1.1
Noisy workplace	0.8	1.0	1.7	-1.3	-0.4
Glaucoma (self-reported)	0.8	1.0	1.7	1.3	-0.5
Arm fat-free mass (right)	0.8	4.0	8.1	-2.8	0.1
Exposure to tobacco smoke outside home	0.8	1.1	1.1	-1.1	1.0
Arm predicted mass (right)	0.8	4.2	8.4	-2.9	-0.3
Illnesses of siblings: Diabetes	0.8	1.0	1.3	-1.2	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	2.1	-1.5	0.7
Pain experienced in last month	0.8	1.4	2.6	-1.6	0.3
Leg fat mass (left)	0.8	3.3	6.2	-2.5	0.6
Arm predicted mass (left)	0.8	3.9	7.7	-2.8	-0.4
Alzheimer’s Disease (including proxy)	0.7	1.0	1.8	-1.4	0.2
Vitamin and mineral supplements	0.7	0.9	1.7	1.3	0.4
Serious illness, injury or assault to yourself	0.7	0.8	1.3	-0.6	-1.2
Heart attack	0.7	0.9	1.5	-0.6	1.2
Alcohol intake versus 10 years previously	0.7	1.1	1.8	0.6	-1.4
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.8	1.0	-0.8	1.0
Hair/balding pattern: Pattern 4	0.7	1.7	2.7	-0.8	1.6
Wheeze or whistling in the chest in last year	0.7	1.2	2.4	-1.6	0.1
Leg fat mass (right)	0.7	2.9	5.2	-2.3	0.7
Arm fat percentage (left)	0.7	2.9	4.7	-2.2	1.0
Smoking status: Current	0.7	1.1	1.9	-0.6	1.4
Average weekly champagne plus white wine intake	0.7	0.9	1.4	0.6	1.2
Alcohol drinker status: Never	0.7	0.9	1.3	-0.7	1.1
Leg fat percentage (left)	0.7	2.7	4.6	-2.1	0.9
Unable to work because of sickness or disability	0.7	0.9	1.8	-0.3	1.3
Heart attack/myocardial infarction (self-reported)	0.7	0.9	1.6	-0.4	1.3
Ulcerative Colitis (UC)	0.6	1.0	1.9	-0.4	-1.4
Reaction Time	0.6	1.1	1.4	-0.8	-1.2
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	1.1	-0.6	-1.1
Diabetes (father)	0.6	0.8	1.1	-0.6	-1.1
Leg fat-free mass (left)	0.6	3.1	3.9	-2.0	-1.5
Relative age voice broke	0.6	0.9	0.9	0.9	-1.0
Multivitamins +/- minerals	0.6	0.8	1.5	-1.2	-0.2
Stomach or abdominal pain in last month	0.6	0.7	0.8	0.9	-0.8
Chronic bronchitis/emphysema (father)	0.6	0.7	1.1	-1.1	0.5
Body mass index (BMI)	0.6	2.5	4.4	-2.1	0.8
Leg predicted mass (left)	0.6	3.0	3.8	-1.9	-1.5
Arm fat percentage (right)	0.6	2.4	4.0	-2.0	0.9
Trunk fat-free mass	0.6	3.3	6.0	-2.5	-0.8
Mouth/teeth dental problems: Dentures	0.6	0.9	1.7	0.5	-1.3
Hypothyroidism/myxoedema (self-reported)	0.6	1.3	2.0	-0.7	-1.4
High blood pressure (siblings)	0.6	0.9	1.8	-1.3	0.2
Leg fat percentage (right)	0.6	2.2	3.0	-1.7	1.1
Number of full sisters	0.6	0.7	1.5	-1.2	-0.1
Whole body fat-free mass	0.6	3.3	5.5	-2.4	-1.0
Leg fat-free mass (right)	0.6	3.4	4.5	-2.1	-1.5
Whole body water mass	0.6	3.2	5.4	-2.3	-1.0
Leg predicted mass (right)	0.6	3.4	4.4	-2.1	-1.5
Miserableness	0.6	1.0	1.7	1.3	0.6
Eye problems/disorders: Glaucoma	0.6	0.7	1.1	1.1	-0.4
Medication: Atorvastatin	0.6	0.7	1.2	1.1	-0.5
Basal metabolic rate	0.6	3.2	5.7	-2.4	-0.8
Arm fat-free mass (left)	0.6	2.9	5.5	-2.4	-0.4
Bipolar Disorder (2018)	0.5	0.7	1.1	-1.1	-0.6
Neuroticism (Nagel 2018)	0.5	1.3	2.1	0.7	1.4
Lupus	0.5	0.8	1.1	0.7	1.0
BMI	0.5	2.8	2.8	-1.6	1.7
Height	0.5	8.7	17.3	-4.2	0.3
Trunk predicted mass	0.5	3.1	5.5	-2.3	-0.8
Gout (self-reported)	0.5	0.7	1.3	-1.1	0.1
Chronic bronchitis/emphysema (mother)	0.5	0.6	0.7	0.7	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.0	-0.4	1.0
Comparative height size at age 10	0.5	2.8	3.9	-1.3	-2.0
Illnesses of father: Heart disease	0.5	0.7	1.1	-0.5	1.0
Loneliness, isolation	0.5	0.7	1.4	1.2	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.3	-0.2	-1.1
Commuting to job workplace: Cycle	0.5	0.6	1.2	-1.1	0.3
Pack years of smoking	0.5	0.7	0.9	-0.9	0.7
Coronary Artery Disease (CAD)	0.4	0.5	0.8	-0.4	0.9
HbA1C	0.4	0.5	0.8	-0.9	0.3
LDL Cholesterol	0.4	0.7	1.3	-1.1	0.3
Neuroticism (2016)	0.4	0.5	1.0	1.0	0.2
Blood White Count	0.4	2.9	3.8	2.0	-1.4
Cardiovascular Disease	0.4	1.2	2.3	0.3	1.5
Chronotype (morning person)	0.4	1.0	1.7	0.5	-1.3
Number of treatments/medications taken	0.4	0.7	1.2	-0.5	1.1
Severe depression (siblings)	0.4	0.4	0.8	-0.9	-0.0
Impedance of leg (right)	0.4	1.7	2.1	1.2	1.5
Hand grip strength (right)	0.4	1.1	2.3	-0.0	-1.5
Current tobacco smoking	0.4	0.7	1.3	-0.1	1.1
Fed-up feelings	0.4	0.7	0.9	0.9	0.8
Medication: Levothyroxine sodium	0.4	0.6	1.2	0.0	-1.1
Number of incorrect matches in round	0.4	0.6	1.2	-0.0	-1.1
Father’s age at death	0.4	0.6	1.1	0.2	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	2.4	-1.6	-0.5
Breastfed as a baby	0.4	0.5	0.9	-0.9	0.2
Ever highly irritable/argumentative for 2 days	0.4	0.4	0.9	-0.1	0.9
Forced vital capacity (FVC), Best measure	0.4	1.6	3.2	-1.8	-0.3
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.1	-1.0	-0.1
Neck or shoulder pain in last month	0.4	0.5	0.7	0.8	-0.6
Medication: Allopurinol	0.4	0.5	0.6	-0.6	0.8
Medication: Seretide 50 evohaler	0.4	0.4	0.8	-0.9	-0.0
Overall health rating	0.4	0.9	1.7	0.4	1.3
Family relationship satisfaction	0.4	0.5	0.6	-0.6	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	0.7	-0.5	0.9
Medication for cholesterol	0.4	0.5	0.9	-0.4	1.0
Breast cancer (self-reported)	0.4	0.5	0.5	-0.7	0.6
Osteoarthritis (self-reported)	0.4	0.5	1.1	-1.0	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	0.8	-0.9	0.9
Guilty feelings	0.4	0.6	0.9	0.6	1.0
High cholesterol (Self-reported)	0.4	0.7	1.5	1.2	0.1
Vascular/heart problems diagnosed by doctor	0.4	1.2	1.7	-1.3	-0.8
Irritable Bowel Disease (IBD)	0.3	0.8	0.9	-0.8	-1.0
Body Mass Index (BMI) (2010)	0.3	0.3	0.5	-0.5	0.7
Hypothyroidism (self reported)	0.3	0.7	1.0	-0.7	-1.0
Medication: Co-codamol	0.3	0.3	0.3	-0.5	0.6
Townsend deprivation index at recruitment	0.3	0.4	0.7	0.2	-0.8
Impedance of leg (left)	0.3	1.4	2.2	0.7	1.5
Nervous feelings	0.3	0.6	1.1	1.1	-0.3
Forced vital capacity (FVC)	0.3	1.3	2.6	-1.6	0.2
Impedance of arm (right)	0.3	1.4	2.6	1.6	-0.5
Time employed in main current job	0.3	0.4	0.8	-0.9	0.2
Worrier / anxious feelings	0.3	0.6	0.8	0.7	-0.9
Lung cancer (father)	0.3	0.3	0.5	-0.4	0.7
Standing height	0.3	3.1	5.3	-2.3	-1.0
Medication: Amlodipine	0.3	0.4	0.7	-0.1	-0.9
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.4	-0.6	-0.5
Number of full brothers	0.3	0.4	0.6	-0.3	-0.8
Qualifications: College or University degree	0.3	0.9	1.7	-1.3	0.3
Medication: Blood pressure	0.3	0.6	0.9	0.9	-0.6
Medication: Ibuprofen	0.3	0.4	0.4	-0.7	0.6
Heart disease (mother)	0.3	0.3	0.6	-0.8	0.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.4	0.5	-0.6
Hypertension (Self-reported)	0.3	0.7	1.3	1.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.1	-1.1	-0.3
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.5	-0.7	0.6
Mother’s age at death	0.3	0.3	0.5	-0.4	-0.7
Financial situation satisfaction	0.3	0.3	0.6	-0.7	0.3
Risk taking	0.3	0.5	0.8	-0.9	0.4
Heart disease (siblings)	0.3	0.3	0.6	0.2	0.8
Intelligence (Savage-Jansen 2018)	0.2	0.7	0.9	0.7	0.9
Crohns Disease (2017)	0.2	0.3	0.4	-0.6	-0.5
Prostate Cancer	0.2	0.3	0.4	0.7	-0.3
Primary Biliary Cirrhosis	0.2	0.3	0.6	-0.0	-0.7
Lung FEV1/FVC ratio	0.2	0.9	1.1	-0.9	1.1
Hand grip strength (left)	0.2	0.7	1.3	-0.1	-1.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.5	-0.7	-0.2
Pack years adult smoking proportion	0.2	0.3	0.5	-0.3	0.7
Maternal smoking around birth	0.2	0.3	0.5	0.2	0.7
High blood pressure	0.2	0.6	1.2	1.1	0.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.4	-0.6	-0.4
Sitting height	0.2	1.1	1.9	-1.4	0.5
Hearing difficulty/problems with background noise	0.2	0.3	0.4	-0.3	0.7
Allergy	0.2	0.5	0.5	-0.7	0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.5	0.4	-0.7
Hair/balding pattern: Pattern 3	0.2	0.3	0.4	0.7	-0.5
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.5	-1.2	0.1
Happiness	0.2	0.2	0.4	0.3	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.3	-0.5	-0.5
Asthma	0.2	0.5	0.8	0.9	-0.3
Tense / ‘highly strung’	0.2	0.4	0.6	0.5	0.7
Peak expiratory flow (PEF)	0.2	0.4	0.6	-0.7	0.6
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.6	0.1	0.8
Medication: Paracetamol	0.2	0.3	0.5	-0.2	0.7
Comparative body size at age 10	0.2	0.5	0.9	-0.2	-0.9
Number of children fathered	0.2	0.2	0.3	-0.5	0.3
Health satisfaction	0.2	0.3	0.3	-0.5	0.6
Suffer from ‘nerves’	0.2	0.3	0.7	0.8	-0.2
Age at last live birth	0.2	0.3	0.3	0.6	0.4
Supplements: Vitamin C	0.2	0.3	0.6	-0.8	0.0
Ever had bowel cancer screening	0.2	0.2	0.3	-0.4	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.4	-0.6	0.3
Asthma (self-reported)	0.2	0.3	0.6	0.8	-0.2
Medication: Aspirin	0.2	0.2	0.3	0.4	0.6
Hearing aid user	0.2	0.2	0.3	0.5	-0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.4	0.6	0.2
Supplements: Calcium	0.2	0.2	0.3	0.5	-0.5
Impedance of whole body	0.2	1.1	1.2	1.0	1.1
Worry (Nagel 2018)	0.1	0.2	0.3	0.6	-0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.4	0.6	0.8	0.3
Breast Cancer	0.1	0.3	0.4	0.4	0.6
Fasting Glucose	0.1	0.1	0.2	-0.3	0.4
HDL Cholesterol	0.1	0.2	0.3	0.3	-0.6
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.2	-0.1	0.4
Ulcerative Colitis	0.1	0.1	0.3	-0.5	-0.1
Blood Eosinophil Count	0.1	0.8	0.9	0.9	-0.8
Heel T-Score	0.1	1.0	1.3	-1.2	-0.8
Smoking Status	0.1	0.3	0.3	0.6	0.5
Respiratory disease	0.1	0.3	0.4	-0.6	0.4
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.3	0.3	0.5
Tanning	0.1	1.2	2.4	-0.0	1.6
Relative age of first facial hair	0.1	0.1	0.3	0.1	-0.5
Systolic blood pressure, automated reading	0.1	0.2	0.3	0.6	-0.4
Medication for hormone replacement therapy	0.1	0.1	0.2	0.5	0.1
Medication: Metformin	0.1	0.2	0.3	-0.5	0.3
Diabetes (mother)	0.1	0.2	0.2	-0.4	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	-0.1	0.5
Taking other prescription medications	0.1	0.2	0.3	-0.5	0.4
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	0.2	-0.3	0.5
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	-0.4	-0.3
Past tobacco smoking	0.1	0.1	0.2	0.1	-0.5
Hair/balding pattern: Pattern 2	0.1	0.1	0.2	0.4	0.1
Diabetes (self-reported)	0.1	0.1	0.2	-0.2	0.5
Illnesses of siblings	0.1	0.2	0.4	0.6	-0.0
Number of live births	0.1	0.2	0.3	-0.5	-0.3
Impedance of arm (left)	0.1	0.4	0.7	0.8	0.4
Birth weight of first child	0.1	0.2	0.2	-0.3	-0.5
Pulse wave reflection index	0.1	0.1	0.1	0.4	-0.2
Headache pain in last month	0.1	0.1	0.2	-0.5	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	0.1	-0.5
Medication for pain relief, constipation, heartburn	0.1	0.2	0.3	0.1	-0.6
Medication: Omeprazole	0.1	0.1	0.1	0.2	-0.3
Chest pain or discomfort	0.1	0.1	0.1	-0.3	-0.3
Had major operations	0.1	0.1	0.3	0.5	0.0
Leg pain on walking	0.1	0.1	0.2	-0.4	-0.3
Medication: Aspirin	0.1	0.1	0.2	-0.1	0.5
Knee pain experienced in last month	0.1	0.1	0.3	0.1	0.5
Diabetes diagnosed by doctor	0.1	0.2	0.3	-0.2	0.6
Eye problems/disorders: Cataract	0.1	0.1	0.2	0.0	-0.5
Back pain experienced in last month	0.1	0.2	0.3	-0.6	0.2
Mineral and other dietary supplements	0.1	0.1	0.2	-0.1	0.4
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.1	-0.5
Medication: Blood pressure	0.1	0.2	0.4	0.7	-0.0
Medication: Bendroflumethiazide	0.1	0.1	0.2	0.4	-0.1
Illnesses of father: High blood pressure	0.1	0.1	0.2	0.5	0.2
Ever smoked	0.1	0.2	0.2	0.3	0.5
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.2	0.2	-0.4
Alzheimer’s Disease (in mother)	0.0	0.0	0.0	-0.1	0.1
Ovarian Cancer	0.0	0.0	0.1	-0.2	0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.1	0.1
Blood Red Count	0.0	0.1	0.1	-0.3	-0.0
Waist Hip Ratio (WHR)	0.0	0.2	0.4	-0.6	-0.1
Lung FVC	0.0	0.0	0.0	-0.1	-0.0
Hair Pigment	0.0	0.1	0.1	0.1	-0.4
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.1	-0.2	-0.1
Hearing difficulty/problems: Yes	0.0	0.0	0.0	-0.2	0.2
Average weekly fortified wine intake	0.0	0.0	0.1	-0.3	-0.1
Qualifications: None of the above	0.0	0.1	0.1	-0.3	0.2
Financial difficulties in last 2 years	0.0	0.0	0.0	0.2	-0.0
Mouth/teeth dental problems	0.0	0.1	0.1	0.3	-0.0
Medication: Ramipril	0.0	0.0	0.1	-0.3	-0.0
Qualifications: A levels/AS levels or equivalent	0.0	0.1	0.1	0.4	0.0
Pulse wave Arterial Stiffness index	0.0	0.1	0.1	-0.3	0.1
Exposure to tobacco smoke at home	0.0	0.0	0.0	-0.1	-0.1
Loud music exposure frequency	0.0	0.0	0.1	0.2	0.2
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.1	-0.2	0.1
Age at first live birth	0.0	0.0	0.0	0.2	-0.1
Pulse wave peak to peak time	0.0	0.0	0.0	0.1	-0.2
Alcohol intake frequency.	0.0	0.0	0.0	0.2	-0.1
Smoking status: Previous	0.0	0.1	0.1	0.3	-0.3
Friendships satisfaction	0.0	0.0	0.0	0.1	0.2
Number of self-reported non-cancer illnesses	0.0	0.0	0.1	-0.3	-0.1
Diastolic blood pressure, automated reading	0.0	0.1	0.1	0.3	0.3
Cholesterol lowering medication	0.0	0.0	0.0	-0.2	0.0
Alcohol drinker status: Previous	0.0	0.0	0.0	0.1	-0.0

Hub : Genes

HNRNPL

Models

Trait associations