TWAS hub - HORMAD1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2080	0.0490	0.0e+00	0.264	0.275	0.292	0.275	0.316	4.2e-32	1.6e-33	6.5e-36	1.5e-33	2.9e-39
2	TCGA	Bladder Urothelial Carcinoma	0.2210	0.0860	0.0e+00	0.350	0.363	0.351	NA	0.371	1.0e-30	4.8e-32	8.2e-31	NA	7.6e-33
3	TCGA	Breast Invasive Carcinoma	0.0577	0.0301	0.0e+00	0.109	0.096	0.096	NA	0.103	1.7e-21	4.3e-19	4.7e-19	NA	2.0e-20
4	TCGA	Cervical Squamous Cell Carcinoma	0.5550	0.1440	0.0e+00	0.353	0.336	0.344	NA	0.371	3.5e-18	3.4e-17	1.1e-17	NA	2.9e-19
5	TCGA	Colon Adenocarcinoma	0.1430	0.0740	1.4e-08	0.140	0.126	0.125	NA	0.132	1.7e-08	9.7e-08	1.1e-07	NA	4.8e-08
6	TCGA	Esophageal Carcinoma	0.3130	0.1150	1.4e-11	0.357	0.256	0.347	NA	0.340	3.3e-12	1.0e-08	7.8e-12	NA	1.4e-11
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.2702	0.0888	0.0e+00	0.536	0.542	0.550	NA	0.551	3.6e-71	3.4e-72	8.9e-74	NA	4.2e-74
8	TCGA	Lung Adenocarcinoma	0.2190	0.0773	0.0e+00	0.402	0.408	0.409	NA	0.412	3.3e-50	3.3e-51	2.3e-51	NA	7.7e-52
9	TCGA	Lung Squamous Cell Carcinoma	0.2586	0.0857	0.0e+00	0.466	0.455	0.460	NA	0.462	3.8e-59	3.1e-57	3.7e-58	NA	2.1e-58
10	TCGA	Ovarian Serous Cystadenocarcinoma	0.1880	0.1000	2.2e-08	0.095	0.116	0.110	NA	0.101	5.9e-07	3.3e-08	7.4e-08	NA	2.7e-07
11	TCGA	Rectum Adenocarcinoma	0.1940	0.1080	5.5e-05	0.142	0.143	0.071	NA	0.100	3.4e-04	3.3e-04	9.8e-03	NA	2.5e-03
12	TCGA	Soft Tissue Sarcoma	0.1440	0.0730	3.6e-09	0.146	0.150	0.133	NA	0.143	5.3e-09	3.2e-09	2.7e-08	NA	8.1e-09
13	TCGA	Skin Cutaneous Melanoma	0.1630	0.0860	3.1e-05	0.173	0.161	0.138	NA	0.146	2.2e-05	4.5e-05	1.6e-04	NA	1.0e-04
14	TCGA	Stomach Adenocarcinoma	0.0960	0.0530	1.1e-10	0.154	0.144	0.144	NA	0.150	2.9e-11	1.3e-10	1.3e-10	NA	5.9e-11
15	TCGA	Testicular Germ Cell Tumors	0.2580	0.1370	2.1e-11	0.244	0.253	0.260	NA	0.300	3.7e-09	1.9e-09	1.1e-09	NA	3.2e-11
16	TCGA	Thyroid Carcinoma	0.1900	0.1000	9.2e-14	0.144	0.152	0.151	NA	0.154	6.8e-14	1.4e-14	1.4e-14	NA	8.3e-15
17	TCGA	Uterine Corpus Endometrial Carcinoma	0.1570	0.1380	2.2e-03	0.113	0.051	0.069	NA	0.067	4.7e-04	1.5e-02	5.5e-03	NA	6.1e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Coronary Artery Disease (CAD)	12.9	15.4	19.2	-3.9	-4.2	-4.1	-3.8	-4.2	-4.4	-3.9	-4.2	-4.0	-3.0	-4.1	-3.7	-4.0	-4.2	-3.7	-4.0	-3.0
Chronotype (morning person)	12.6	29.1	34.0	-4.3	-5.5	-5.5	-4.9	-5.6	-5.7	-5.5	-5.6	-5.6	-5.4	-5.7	-5.8	-5.4	-5.5	-5.2	-5.4	-4.8
Blood Eosinophil Count	12.4	95.4	125.4	11.2	9.2	8.9	11.1	8.7	9.7	10.7	9.7	10.5	8.1	10.1	9.3	10.6	9.3	10.7	8.9	8.5
Lung FVC	11.5	58.7	79.1	8.6	8.0	8.0	7.7	7.7	8.9	7.5	7.9	7.6	4.3	7.9	6.7	8.1	8.0	7.1	8.0	7.1
Irritable Bowel Disease (IBD)	10.9	25.9	30.4	-5.0	-5.3	-5.5	-4.8	-5.2	-5.1	-5.0	-5.1	-4.9	-4.6	-5.2	-5.2	-5.2	-5.4	-4.8	-5.2	-5.0
Mouth/teeth dental problems: Mouth ulcers	10.4	16.6	21.4	4.5	4.0	3.8	4.5	3.8	4.6	4.4	4.1	4.3	2.6	4.3	3.7	4.4	4.0	4.3	3.9	3.4
Ulcerative Colitis (UC)	8.2	15.4	17.6	-3.7	-4.0	-4.2	-3.8	-3.8	-4.0	-4.0	-3.9	-3.8	-3.7	-4.1	-4.1	-4.0	-4.2	-3.9	-3.9	-3.6
Forced vital capacity (FVC)	8.2	31.7	41.7	6.2	5.8	5.9	5.7	5.7	6.5	5.5	5.8	5.5	3.3	5.9	5.0	5.9	5.9	5.4	6.0	5.2
Forced vital capacity (FVC), Best measure	8.0	29.3	43.4	6.3	5.6	5.5	5.7	5.3	6.6	5.3	5.5	5.3	2.3	5.7	4.4	5.8	5.6	5.1	5.6	5.0
Qualifications: CSEs or equivalent	7.3	9.7	10.7	-2.8	-3.2	-3.2	-2.8	-3.2	-3.3	-3.1	-3.3	-3.3	-2.9	-3.2	-3.1	-3.2	-3.2	-2.8	-3.1	-3.2
Ulcerative Colitis	6.7	9.7	12.5	-2.3	-3.2	-3.1	-2.9	-3.2	-3.1	-3.3	-3.3	-3.3	-3.5	-3.3	-3.4	-3.1	-3.2	-3.2	-3.1	-1.9
Crohns Disease (2017)	6.4	14.0	16.8	-3.9	-3.9	-4.1	-3.5	-3.8	-3.8	-3.5	-3.8	-3.6	-3.1	-3.8	-3.6	-3.8	-4.0	-3.4	-3.9	-3.9
Had other major operations	5.7	7.0	11.3	2.4	2.8	2.8	2.2	2.7	3.1	2.5	2.8	2.8	1.9	2.7	2.5	2.7	2.7	2.0	2.6	3.4
Blood Platelet Count	5.0	58.0	74.1	8.6	7.9	8.2	7.6	8.0	6.8	7.2	7.6	6.9	6.7	7.4	7.4	7.6	8.0	7.5	8.4	7.3
Tanning	5.0	61.1	80.8	9.0	7.6	7.4	8.9	7.2	8.2	8.3	7.8	8.0	5.4	8.2	7.3	8.3	7.7	8.7	7.7	6.4
Forced expiratory volume in 1-second (FEV1)	4.8	16.0	22.8	4.6	4.3	4.3	4.0	4.2	4.8	3.8	4.1	3.8	1.9	4.2	3.4	4.2	4.3	3.6	4.4	3.7
Impedance of arm (right)	4.7	21.7	23.8	-4.8	-4.8	-4.9	-4.3	-4.8	-4.3	-4.5	-4.8	-4.6	-4.6	-4.6	-4.7	-4.7	-4.8	-4.2	-4.8	-4.8
Commuting to job workplace: Car/motor vehicle	4.6	5.2	7.4	-2.5	-2.2	-2.0	-2.5	-2.1	-2.4	-2.4	-2.2	-2.3	-1.6	-2.4	-2.2	-2.4	-2.2	-2.4	-2.2	-2.7
Angina (self-reported)	4.4	5.7	10.3	-3.2	-2.4	-2.5	-2.7	-2.4	-2.4	-2.3	-2.4	-2.2	-1.3	-2.4	-2.0	-2.6	-2.4	-2.4	-2.6	-2.2
Trunk fat percentage	4.1	16.4	20.7	-3.7	-4.2	-4.2	-3.7	-4.2	-3.7	-3.9	-4.2	-4.0	-4.1	-3.9	-4.2	-4.0	-4.2	-3.7	-4.2	-4.6
Forced expiratory volume in 1-second (FEV1), Best measure	4.1	13.0	20.5	4.5	3.8	3.8	3.7	3.6	4.5	3.4	3.7	3.5	1.1	3.7	2.7	3.9	3.8	3.2	3.8	3.2
Impedance of arm (left)	4.1	19.0	20.4	-4.5	-4.5	-4.5	-4.1	-4.4	-4.0	-4.3	-4.4	-4.3	-4.3	-4.3	-4.4	-4.4	-4.5	-4.1	-4.4	-4.5
Commuting to job workplace: Walk	4.1	4.5	5.6	-2.3	-2.1	-2.1	-2.3	-2.1	-2.4	-2.2	-2.2	-2.1	-1.3	-2.2	-1.9	-2.3	-2.2	-2.2	-2.2	-1.6
Mean Putamen Volume	3.9	4.4	5.3	-2.3	-2.2	-2.2	-2.2	-2.1	-2.2	-2.1	-2.2	-2.2	-1.7	-2.1	-1.9	-2.3	-2.2	-2.0	-2.1	-1.6
Noisy workplace	3.9	4.8	7.2	-2.1	-2.2	-2.2	-2.2	-2.1	-2.7	-2.3	-2.3	-2.3	-1.3	-2.3	-2.0	-2.3	-2.2	-2.1	-2.1	-2.4
Body fat percentage	3.9	15.3	18.9	-3.6	-4.1	-4.1	-3.5	-4.1	-3.7	-3.8	-4.1	-3.9	-3.8	-3.8	-3.9	-3.9	-4.1	-3.5	-4.0	-4.3
Impedance of whole body	3.9	19.6	23.4	-4.8	-4.6	-4.6	-4.3	-4.5	-4.5	-4.4	-4.5	-4.5	-3.7	-4.4	-4.2	-4.6	-4.6	-4.1	-4.5	-4.4
Crohns Disease (2012)	3.8	6.2	7.6	-2.6	-2.6	-2.5	-2.4	-2.6	-2.8	-2.5	-2.6	-2.6	-1.9	-2.6	-2.4	-2.6	-2.7	-2.3	-2.6	-1.7
Birth weight of first child	3.8	6.8	8.0	2.8	2.6	2.6	2.7	2.5	2.8	2.7	2.7	2.7	1.8	2.7	2.4	2.8	2.6	2.6	2.6	2.7
Vitamin and mineral supplements	3.7	5.1	6.2	2.5	2.4	2.4	2.2	2.4	2.2	2.2	2.3	2.2	2.0	2.2	2.2	2.3	2.4	2.1	2.4	1.9
Angina	3.6	4.7	8.7	-3.0	-2.2	-2.3	-2.4	-2.1	-2.3	-2.1	-2.2	-2.0	-1.1	-2.1	-1.7	-2.4	-2.2	-2.1	-2.3	-1.9
Illness, injury, bereavement, stress in last 2 years	3.6	4.4	7.3	2.7	2.0	2.0	2.4	1.9	2.1	2.1	2.0	2.0	1.2	2.1	1.8	2.2	2.1	2.3	2.2	2.2
Average weekly champagne plus white wine intake	3.6	5.0	5.6	2.2	2.4	2.4	2.1	2.3	2.3	2.2	2.3	2.2	1.8	2.2	2.1	2.3	2.4	2.0	2.4	2.3
Average weekly fortified wine intake	3.5	4.1	5.7	2.3	1.9	1.9	2.3	1.8	2.4	2.1	2.0	2.0	1.1	2.1	1.8	2.1	1.9	2.1	1.9	2.3
Number of operations (self-reported)	3.5	5.2	7.8	2.5	2.4	2.4	2.1	2.2	2.8	2.2	2.4	2.4	1.1	2.3	1.9	2.5	2.3	1.8	2.2	2.8
Hand grip strength (left)	3.4	9.1	11.8	3.2	3.3	3.3	2.8	3.3	3.4	2.8	3.1	2.8	1.8	3.1	2.7	3.1	3.3	2.7	3.4	2.4
Impedance of leg (right)	3.4	16.7	24.4	-4.9	-4.2	-4.2	-4.3	-3.9	-4.5	-4.0	-4.2	-4.1	-2.4	-4.2	-3.5	-4.4	-4.2	-3.9	-4.1	-4.0
Serious illness, injury or assault to yourself	3.4	4.2	4.7	-2.2	-2.1	-2.0	-2.1	-2.0	-2.1	-2.1	-2.1	-2.1	-1.6	-2.1	-1.9	-2.2	-2.1	-2.0	-2.1	-2.1
Wheeze or whistling in the chest in last year	3.3	5.9	7.1	1.9	2.5	2.4	2.2	2.5	2.5	2.5	2.5	2.6	2.5	2.5	2.7	2.4	2.4	2.4	2.4	2.5
Age started oral contraceptive pill	3.3	4.1	4.7	1.7	2.1	2.1	1.9	2.1	2.0	2.1	2.1	2.1	2.2	2.1	2.1	2.1	2.0	1.9	2.0	1.9
Medication: Levothyroxine sodium	3.1	5.3	6.2	-2.5	-2.3	-2.4	-2.4	-2.3	-2.2	-2.4	-2.4	-2.4	-2.0	-2.3	-2.2	-2.4	-2.3	-2.3	-2.3	-1.8
Medication: Blood pressure	3.1	5.4	7.1	-2.3	-2.5	-2.5	-2.1	-2.4	-2.7	-2.2	-2.5	-2.3	-1.6	-2.4	-2.1	-2.4	-2.5	-1.9	-2.4	-2.5
Peak expiratory flow (PEF)	3.0	7.0	11.2	3.0	2.9	3.0	2.4	2.8	3.4	2.4	2.8	2.5	1.0	2.7	2.1	2.8	2.9	2.1	2.9	2.4
Alzheimer’s Disease (in mother)	2.9	3.4	4.8	-1.9	-1.9	-1.8	-1.9	-1.9	-2.0	-1.8	-1.8	-1.7	-1.2	-1.9	-1.7	-1.9	-1.9	-1.9	-1.9	-2.2
Smoking Status	2.9	6.9	8.2	2.2	2.7	2.5	2.5	2.7	2.7	2.8	2.7	2.9	2.8	2.8	2.8	2.7	2.6	2.5	2.5	2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.9	6.2	10.1	3.0	2.7	2.7	2.3	2.6	3.2	2.2	2.6	2.3	0.8	2.5	1.9	2.6	2.7	1.9	2.7	2.4
Arm fat percentage (right)	2.7	10.6	14.3	-2.9	-3.4	-3.4	-2.9	-3.4	-2.9	-3.1	-3.4	-3.2	-3.4	-3.1	-3.4	-3.2	-3.4	-2.9	-3.4	-3.8
Hearing difficulty/problems: Yes	2.6	4.0	5.2	1.7	2.0	1.9	2.0	2.0	1.9	2.2	2.1	2.2	2.3	2.1	2.2	2.1	2.0	2.1	1.9	1.1
Prospective memory result	2.6	3.1	4.6	-1.5	-1.7	-1.6	-2.0	-1.8	-1.8	-1.9	-1.7	-1.7	-1.6	-2.0	-2.0	-1.7	-1.7	-2.1	-1.8	-1.3
Arm fat percentage (left)	2.5	9.8	13.3	-2.8	-3.2	-3.2	-2.8	-3.3	-2.8	-3.0	-3.2	-3.1	-3.3	-3.0	-3.2	-3.1	-3.2	-2.8	-3.2	-3.6
Supplements: Fish oil (including cod liver oil)	2.5	3.3	4.2	-1.8	-1.9	-2.0	-1.6	-1.9	-1.4	-1.7	-1.8	-1.7	-2.0	-1.7	-1.9	-1.8	-1.9	-1.7	-2.0	-1.9
Basal cell carcinoma (self-reported)	2.5	3.0	4.4	-2.0	-1.6	-1.5	-2.1	-1.4	-2.0	-2.0	-1.7	-1.9	-0.9	-1.9	-1.5	-1.9	-1.6	-2.0	-1.6	-1.1
Heel T-Score	2.4	18.8	26.7	4.4	4.3	4.2	4.6	4.2	5.2	4.5	4.4	4.5	2.6	4.7	4.1	4.6	4.3	4.6	4.3	3.4
Chronic bronchitis/emphysema (father)	2.4	2.8	3.2	1.7	1.7	1.6	1.7	1.6	1.5	1.8	1.7	1.8	1.7	1.7	1.7	1.8	1.7	1.7	1.6	1.5
Impedance of leg (left)	2.4	11.7	17.4	-4.2	-3.5	-3.5	-3.6	-3.3	-3.9	-3.4	-3.5	-3.4	-1.9	-3.5	-2.9	-3.7	-3.5	-3.3	-3.5	-3.0
Lung FEV1/FVC ratio	2.3	11.7	13.4	-3.1	-3.5	-3.4	-3.4	-3.4	-3.6	-3.6	-3.5	-3.7	-3.1	-3.6	-3.5	-3.6	-3.5	-3.5	-3.4	-3.0
Eye problems/disorders: Diabetes related eye disease	2.3	2.5	5.8	-1.6	-1.5	-1.5	-1.5	-1.6	-1.2	-1.5	-1.5	-1.4	-1.6	-1.5	-1.7	-1.4	-1.5	-1.6	-1.6	-2.4
Glaucoma (self-reported)	2.3	2.8	3.8	-2.0	-1.8	-1.8	-1.6	-1.8	-1.8	-1.5	-1.7	-1.5	-1.0	-1.6	-1.5	-1.7	-1.8	-1.5	-1.9	-1.6
Leg fat percentage (right)	2.3	8.2	10.5	-2.8	-3.0	-3.0	-2.7	-3.0	-2.9	-2.8	-3.0	-2.9	-2.4	-2.8	-2.7	-2.9	-3.0	-2.6	-3.0	-3.2
Myopia	2.3	3.3	4.3	1.3	1.9	1.8	1.6	1.9	1.8	1.9	1.9	1.9	2.1	1.9	2.0	1.8	1.9	1.7	1.8	1.5
Primary Biliary Cirrhosis	2.2	3.2	5.1	2.2	1.6	1.7	2.3	1.5	2.0	1.8	1.7	1.7	0.7	1.9	1.5	1.9	1.7	2.1	1.7	1.9
Happiness	2.2	2.6	3.8	1.8	1.6	1.5	1.9	1.5	1.5	1.7	1.6	1.6	1.4	1.7	1.7	1.7	1.6	1.9	1.6	1.2
Neck or shoulder pain in last month	2.2	3.1	4.0	1.5	1.9	1.8	1.5	1.9	2.0	1.7	1.9	1.8	1.5	1.9	1.8	1.8	1.9	1.5	1.9	1.5
Guilty feelings	2.2	3.3	5.6	2.3	1.6	1.6	2.4	1.5	1.9	2.0	1.7	1.8	0.9	1.9	1.6	1.9	1.6	2.2	1.7	1.7
Hand grip strength (right)	2.1	5.6	7.7	2.3	2.7	2.7	1.9	2.7	2.8	2.1	2.5	2.2	1.6	2.4	2.1	2.4	2.7	1.8	2.7	1.9
Medication: Aspirin	2.1	2.7	4.4	-1.9	-1.7	-1.7	-1.6	-1.6	-1.8	-1.5	-1.6	-1.5	-1.0	-1.6	-1.5	-1.7	-1.7	-1.5	-1.7	-2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.1	2.4	3.5	1.7	1.5	1.5	1.9	1.4	1.9	1.7	1.6	1.7	0.9	1.7	1.4	1.7	1.5	1.8	1.5	0.9
Medication: Aspirin	2.1	2.7	4.2	-2.0	-1.6	-1.6	-1.9	-1.5	-1.8	-1.7	-1.6	-1.6	-0.9	-1.7	-1.4	-1.7	-1.6	-1.7	-1.6	-1.8
Smoking status: Current	2.1	3.3	5.5	1.4	1.8	1.7	1.6	1.8	1.6	1.9	1.9	1.9	2.3	1.8	2.1	1.8	1.8	1.8	1.7	1.9
Allergy or Eczema	2.0	5.2	7.6	-1.5	-2.5	-2.5	-1.6	-2.6	-2.4	-2.1	-2.4	-2.2	-2.6	-2.3	-2.6	-2.1	-2.4	-1.7	-2.3	-2.8
Trunk fat mass	2.0	8.7	11.6	-2.6	-3.0	-3.0	-2.6	-3.1	-2.5	-2.8	-3.0	-2.9	-3.3	-2.8	-3.1	-2.9	-3.0	-2.7	-3.1	-3.4
Lung cancer (father)	2.0	2.3	4.2	-1.7	-1.5	-1.4	-1.6	-1.4	-2.1	-1.5	-1.5	-1.5	-0.4	-1.6	-1.2	-1.6	-1.5	-1.5	-1.5	-1.7
Hypothyroidism/myxoedema (self-reported)	2.0	4.0	4.8	-2.1	-2.1	-2.2	-1.8	-2.1	-1.9	-1.9	-2.1	-2.0	-1.9	-1.9	-1.9	-2.1	-2.1	-1.7	-2.1	-1.9
Worry too long after embarrassment	2.0	3.3	6.1	2.2	1.5	1.5	2.5	1.4	1.8	2.0	1.6	1.8	1.1	1.9	1.7	1.9	1.6	2.4	1.6	2.0
Pain experienced in last month	2.0	3.4	4.1	-1.4	-2.0	-1.9	-1.5	-2.0	-2.0	-1.9	-2.0	-2.0	-2.0	-2.0	-2.0	-1.9	-1.9	-1.6	-1.9	-1.2
Body Mass Index (BMI) (2010)	1.9	2.6	3.5	-1.8	-1.6	-1.6	-1.8	-1.6	-1.5	-1.6	-1.6	-1.5	-1.4	-1.7	-1.7	-1.6	-1.6	-1.9	-1.7	-1.1
Hypothyroidism (self reported)	1.9	4.4	5.1	-2.2	-2.2	-2.3	-2.0	-2.2	-2.0	-2.0	-2.2	-2.1	-1.9	-2.0	-2.0	-2.2	-2.2	-1.9	-2.2	-1.9
Multivitamins +/- minerals	1.9	2.4	3.3	-1.8	-1.7	-1.7	-1.5	-1.6	-1.8	-1.5	-1.6	-1.5	-0.9	-1.5	-1.3	-1.7	-1.7	-1.3	-1.7	-1.3
Ever unenthusiastic/disinterested for a whole week	1.9	2.3	2.9	1.7	1.6	1.6	1.5	1.6	1.7	1.5	1.6	1.6	1.1	1.6	1.4	1.6	1.6	1.4	1.6	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.3	3.6	-1.0	-1.6	-1.6	-1.2	-1.6	-1.9	-1.5	-1.6	-1.6	-1.3	-1.6	-1.5	-1.5	-1.5	-1.1	-1.4	-1.9
Prostate Cancer	1.8	2.6	12.9	0.4	1.4	1.6	0.8	1.8	0.2	1.2	1.4	1.1	3.6	1.3	2.4	0.9	1.5	1.5	1.6	1.5
Headache pain in last month	1.8	3.0	4.1	1.4	2.0	2.0	1.4	2.0	1.8	1.7	1.9	1.8	1.8	1.8	1.8	1.8	2.0	1.4	2.0	0.7
Supplements: Vitamin C	1.8	2.1	4.0	-1.4	-1.4	-1.3	-1.5	-1.4	-1.0	-1.6	-1.4	-1.5	-2.0	-1.4	-1.6	-1.5	-1.4	-1.6	-1.4	-0.7
Systolic blood pressure, automated reading	1.7	4.8	7.5	-2.7	-2.3	-2.4	-2.1	-2.2	-2.7	-2.0	-2.3	-2.2	-0.7	-2.2	-1.6	-2.4	-2.3	-1.7	-2.3	-2.2
Financial difficulties in last 2 years	1.7	2.3	2.8	1.6	1.6	1.7	1.5	1.6	1.4	1.5	1.6	1.5	1.6	1.5	1.6	1.6	1.6	1.5	1.6	1.1
Mouth/teeth dental problems: Loose teeth	1.7	2.0	2.3	1.4	1.5	1.5	1.4	1.5	1.4	1.4	1.5	1.4	1.4	1.5	1.5	1.4	1.5	1.5	1.5	0.9
Mineral and other dietary supplements	1.7	2.3	3.4	1.9	1.6	1.6	1.5	1.6	1.0	1.4	1.5	1.3	1.6	1.4	1.5	1.5	1.6	1.5	1.7	1.5
Hair/balding pattern: Pattern 2	1.6	2.0	4.2	-1.3	-1.3	-1.3	-1.5	-1.3	-0.8	-1.5	-1.4	-1.4	-2.1	-1.3	-1.6	-1.4	-1.4	-1.6	-1.3	-0.9
Hair/balding pattern: Pattern 4	1.6	3.9	7.7	1.4	1.9	2.0	1.7	2.0	1.5	1.9	2.0	2.0	2.8	1.9	2.4	1.8	2.0	1.9	1.9	1.8
Medication for cholesterol, blood pressure or diabetes	1.6	2.7	4.0	1.5	1.8	1.8	1.2	1.8	1.8	1.5	1.8	1.6	1.4	1.6	1.6	1.6	1.8	1.1	1.8	2.0
Whole body fat mass	1.6	6.7	8.9	-2.2	-2.7	-2.7	-2.3	-2.7	-2.2	-2.5	-2.7	-2.5	-2.8	-2.5	-2.7	-2.5	-2.7	-2.3	-2.7	-3.0
Breast cancer (self-reported)	1.6	1.9	2.4	-1.2	-1.5	-1.6	-1.1	-1.5	-1.4	-1.3	-1.5	-1.4	-1.5	-1.4	-1.4	-1.4	-1.5	-1.1	-1.4	-1.3
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.4	3.3	1.6	1.4	1.4	1.8	1.4	1.6	1.6	1.5	1.5	1.2	1.6	1.6	1.5	1.4	1.8	1.5	1.6
Medication: Ramipril	1.5	1.9	4.4	-2.1	-1.3	-1.5	-1.6	-1.3	-1.4	-1.2	-1.2	-1.1	-0.4	-1.3	-1.1	-1.3	-1.4	-1.4	-1.5	-1.8
Medication: Ibuprofen	1.5	1.8	3.4	-1.4	-1.1	-1.1	-1.6	-1.2	-0.6	-1.4	-1.2	-1.2	-1.9	-1.3	-1.6	-1.3	-1.2	-1.8	-1.3	-1.2
Risk taking	1.5	2.3	2.7	1.6	1.5	1.4	1.6	1.4	1.6	1.6	1.5	1.6	1.1	1.6	1.4	1.6	1.5	1.6	1.4	1.4
Father’s age at death	1.4	1.9	3.9	0.7	1.5	1.6	0.9	1.5	1.6	1.3	1.5	1.5	1.4	1.3	1.4	1.4	1.4	0.8	1.3	2.0
Qualifications: A levels/AS levels or equivalent	1.4	3.0	3.4	1.8	1.8	1.7	1.7	1.8	1.7	1.7	1.7	1.6	1.6	1.8	1.8	1.7	1.8	1.8	1.8	1.8
Birth weight	1.4	3.0	4.8	2.2	1.7	1.7	1.9	1.6	1.4	1.7	1.7	1.7	1.5	1.6	1.6	1.8	1.7	1.9	1.8	2.0
Leg pain on walking	1.4	1.7	3.3	-1.8	-1.3	-1.2	-1.6	-1.3	-1.6	-1.2	-1.2	-1.0	-0.0	-1.3	-0.9	-1.4	-1.4	-1.4	-1.5	-1.5
Diabetes diagnosed by doctor	1.4	2.3	5.2	-1.3	-1.7	-1.7	-0.9	-1.8	-1.1	-1.1	-1.5	-1.2	-1.6	-1.3	-1.5	-1.3	-1.7	-1.0	-1.8	-2.3
Leg fat percentage (left)	1.4	5.0	5.7	-2.0	-2.4	-2.4	-2.0	-2.4	-2.2	-2.1	-2.4	-2.2	-2.0	-2.2	-2.2	-2.3	-2.4	-2.0	-2.4	-2.4
Supplements: Calcium	1.4	1.6	2.3	-1.5	-1.3	-1.3	-1.2	-1.4	-0.8	-1.1	-1.2	-1.0	-1.4	-1.1	-1.3	-1.2	-1.4	-1.3	-1.5	-1.2
BMI	1.3	7.8	9.2	-2.3	-2.9	-2.9	-2.5	-2.9	-2.6	-2.7	-2.9	-2.8	-3.0	-2.8	-3.0	-2.7	-2.9	-2.6	-2.9	-3.0
Current tobacco smoking	1.3	2.1	4.0	1.0	1.4	1.4	1.2	1.5	1.3	1.5	1.5	1.6	2.0	1.5	1.8	1.4	1.4	1.3	1.4	1.6
Time employed in main current job	1.3	1.5	2.8	1.7	1.3	1.4	1.3	1.3	1.3	1.2	1.2	1.2	0.8	1.2	1.1	1.3	1.3	1.2	1.3	1.0
Medication: Cholesterol lowering	1.3	2.0	3.0	-1.6	-1.5	-1.5	-1.3	-1.5	-1.3	-1.3	-1.4	-1.3	-1.2	-1.4	-1.3	-1.4	-1.5	-1.2	-1.5	-1.7
Trunk predicted mass	1.3	7.3	10.3	2.8	2.9	2.8	2.5	2.7	3.2	2.7	2.9	2.8	1.8	2.8	2.4	2.9	2.8	2.3	2.7	2.6
Mouth/teeth dental problems: Bleeding gums	1.3	1.6	3.7	-0.6	-1.2	-1.2	-1.1	-1.3	-1.0	-1.3	-1.3	-1.3	-1.9	-1.3	-1.7	-1.2	-1.2	-1.4	-1.2	-1.1
Comparative body size at age 10	1.3	3.6	4.6	-1.9	-1.9	-1.9	-2.0	-1.9	-2.1	-2.0	-1.9	-1.9	-1.3	-2.0	-1.8	-2.0	-1.9	-2.0	-2.0	-1.5
Number of full brothers	1.3	1.6	2.1	-1.3	-1.4	-1.4	-1.0	-1.4	-1.1	-1.1	-1.3	-1.2	-1.3	-1.2	-1.2	-1.3	-1.4	-1.0	-1.4	-1.1
Qualifications: College or University degree	1.3	4.0	5.4	1.8	2.0	2.0	2.0	2.1	2.3	1.9	2.0	1.9	1.2	2.2	1.9	2.0	2.1	2.0	2.1	2.0
Handedness (chirality/laterality): Left-handed	1.3	1.5	2.3	-1.2	-1.4	-1.5	-1.0	-1.4	-1.3	-1.1	-1.3	-1.2	-1.1	-1.2	-1.2	-1.2	-1.4	-1.0	-1.4	-0.9
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	2.0	-1.3	-1.4	-1.4	-1.1	-1.4	-1.3	-1.1	-1.3	-1.2	-0.8	-1.2	-1.1	-1.3	-1.4	-1.0	-1.4	-1.3
Depression (Nagel 2018)	1.2	1.8	2.5	0.8	1.2	1.2	1.2	1.3	1.6	1.5	1.4	1.6	1.4	1.5	1.5	1.4	1.0	1.3	1.1	1.5
Trunk fat-free mass	1.2	7.1	10.0	2.8	2.8	2.8	2.5	2.7	3.2	2.6	2.8	2.8	1.7	2.8	2.4	2.8	2.8	2.2	2.7	2.6
Pulse rate	1.2	2.0	4.3	2.1	1.4	1.4	1.6	1.3	1.8	1.3	1.4	1.3	0.0	1.4	0.9	1.5	1.4	1.4	1.5	1.5
Medication: Ventolin 100micrograms inhaler	1.2	1.6	2.4	1.4	1.2	1.2	1.5	1.1	1.4	1.4	1.3	1.3	0.6	1.3	1.1	1.4	1.2	1.4	1.2	1.1
High blood pressure (siblings)	1.2	1.7	3.0	0.9	1.2	1.2	1.1	1.3	1.1	1.3	1.3	1.3	1.7	1.3	1.6	1.2	1.2	1.4	1.3	1.4
Medication for cholesterol	1.2	1.8	4.8	-0.4	-1.4	-1.4	-0.7	-1.5	-1.0	-1.2	-1.4	-1.3	-2.2	-1.3	-1.8	-1.1	-1.3	-1.0	-1.3	-1.6
Commuting to job workplace: Public transport	1.2	1.4	2.6	1.5	1.0	0.8	1.6	0.9	1.2	1.4	1.0	1.2	0.6	1.2	1.1	1.3	1.0	1.6	1.0	1.4
Type 2 Diabetes (T2D) (2012)	1.1	1.2	2.1	1.1	1.0	0.9	1.4	0.9	1.1	1.3	1.0	1.2	0.8	1.2	1.1	1.2	1.0	1.4	1.1	0.6
Blood White Count	1.1	8.2	11.8	3.4	2.7	2.5	3.2	2.4	3.1	3.3	2.9	3.4	2.3	3.0	2.6	3.3	2.7	2.9	2.4	2.4
Diabetes (mother)	1.1	1.4	2.7	1.0	1.0	1.0	1.4	1.1	0.9	1.3	1.0	1.0	1.5	1.3	1.6	1.0	1.0	1.7	1.1	1.0
Supplements: Glucosamine	1.1	1.4	2.3	-1.5	-1.2	-1.1	-1.2	-1.2	-0.8	-1.1	-1.1	-1.0	-1.2	-1.0	-1.1	-1.2	-1.3	-1.2	-1.3	-1.3
Heart attack	1.1	1.4	3.1	-1.7	-1.0	-1.1	-1.6	-1.0	-1.2	-1.2	-1.1	-1.1	-0.5	-1.2	-1.0	-1.3	-1.1	-1.4	-1.1	-1.1
Worrier / anxious feelings	1.1	2.2	4.8	-0.9	-1.6	-1.5	-0.9	-1.6	-1.2	-1.4	-1.6	-1.5	-2.2	-1.4	-1.7	-1.4	-1.5	-1.0	-1.4	-1.6
Leg fat mass (right)	1.1	4.2	5.8	-1.9	-2.1	-2.1	-1.9	-2.1	-1.9	-2.0	-2.1	-2.0	-2.0	-2.0	-2.0	-2.0	-2.1	-1.9	-2.1	-2.4
Arm predicted mass (right)	1.1	5.5	7.6	2.5	2.5	2.5	2.1	2.4	2.8	2.3	2.5	2.5	1.6	2.4	2.1	2.5	2.5	1.9	2.4	2.2
Number of full sisters	1.1	1.4	2.2	-0.6	-1.1	-1.2	-1.0	-1.2	-1.1	-1.2	-1.2	-1.2	-1.5	-1.2	-1.4	-1.1	-1.1	-1.1	-1.1	-1.5
Long-standing illness, disability or infirmity	1.1	1.7	2.2	-1.3	-1.5	-1.4	-1.0	-1.4	-1.2	-1.2	-1.4	-1.3	-1.3	-1.2	-1.2	-1.4	-1.4	-0.9	-1.4	-1.5
LDL Cholesterol	1.0	1.5	1.9	0.7	1.4	1.3	1.1	1.3	1.3	1.3	1.4	1.4	1.3	1.3	1.3	1.3	1.4	1.1	1.2	0.9
Schizophrenia (2014)	1.0	2.2	3.7	1.8	1.5	1.7	1.7	1.5	1.9	1.4	1.4	1.2	0.3	1.6	1.3	1.5	1.5	1.6	1.7	1.1
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	2.7	-1.3	-0.9	-0.9	-1.5	-0.9	-0.5	-1.2	-0.9	-1.0	-1.5	-1.1	-1.3	-1.0	-1.0	-1.6	-1.0	-1.0
Depression (self-reported)	1.0	1.2	1.9	0.8	1.0	1.0	1.2	1.0	1.4	1.3	1.1	1.2	0.8	1.3	1.2	1.1	1.0	1.3	1.0	1.0
Medication: Lansoprazole	1.0	1.1	1.9	-1.4	-0.9	-0.8	-1.4	-0.8	-1.3	-1.2	-1.0	-1.1	-0.2	-1.1	-0.8	-1.2	-0.9	-1.2	-0.8	-0.9
Pack years of smoking	1.0	1.5	2.1	1.4	1.1	1.0	1.4	1.0	1.4	1.4	1.2	1.4	0.8	1.3	1.1	1.4	1.1	1.3	1.0	1.4
Systolic Blood Pressure	0.9	4.5	9.3	-3.0	-2.1	-2.2	-2.3	-1.8	-3.0	-2.0	-2.2	-2.1	0.1	-2.1	-1.1	-2.4	-2.1	-1.6	-2.0	-2.2
Age when periods started (menarche)	0.9	2.2	4.1	2.0	1.4	1.3	1.8	1.2	1.5	1.5	1.4	1.4	0.6	1.4	1.2	1.6	1.4	1.7	1.4	1.8
Mouth/teeth dental problems	0.9	1.4	2.2	-0.9	-1.3	-1.3	-0.8	-1.3	-1.0	-1.1	-1.3	-1.2	-1.5	-1.1	-1.2	-1.2	-1.3	-0.8	-1.2	-1.3
Diabetes (self-reported)	0.9	1.4	4.4	-1.0	-1.3	-1.3	-0.7	-1.4	-0.9	-0.8	-1.2	-0.9	-1.0	-1.0	-1.1	-1.0	-1.3	-0.7	-1.4	-2.1
Number of live births	0.9	1.3	2.0	-0.7	-1.1	-1.1	-1.0	-1.1	-1.1	-1.2	-1.1	-1.2	-1.4	-1.2	-1.4	-1.0	-1.1	-1.2	-1.1	-1.3
Arm fat mass (right)	0.9	3.6	5.6	-1.5	-2.0	-2.0	-1.6	-2.0	-1.5	-1.8	-2.0	-1.9	-2.4	-1.8	-2.1	-1.8	-2.0	-1.7	-2.0	-2.3
Arm fat-free mass (right)	0.9	4.4	5.8	2.2	2.2	2.2	1.8	2.2	2.4	2.0	2.2	2.2	1.6	2.1	1.9	2.2	2.2	1.7	2.1	2.1
Family relationship satisfaction	0.9	1.1	2.0	1.4	0.9	0.9	1.3	1.0	0.7	1.1	0.9	0.9	1.0	1.0	1.1	1.0	1.0	1.4	1.1	0.4
Illnesses of siblings: Diabetes	0.9	1.1	1.4	-0.9	-1.2	-1.2	-0.8	-1.1	-1.1	-0.9	-1.1	-1.1	-0.8	-1.0	-0.9	-1.1	-1.2	-0.7	-1.1	-1.1
Whole body fat-free mass	0.9	4.9	8.1	2.6	2.3	2.3	2.1	2.2	2.8	2.2	2.3	2.3	1.0	2.3	1.8	2.4	2.3	1.9	2.2	2.0
Whole body water mass	0.9	4.9	8.0	2.6	2.3	2.3	2.2	2.2	2.8	2.2	2.3	2.3	1.0	2.3	1.8	2.4	2.3	1.9	2.2	2.0
Ever taken oral contraceptive pill	0.9	1.0	1.7	-1.3	-0.9	-0.8	-1.2	-0.8	-1.2	-1.1	-1.0	-1.1	-0.4	-1.0	-0.7	-1.2	-0.9	-1.0	-0.9	-0.5
Eye problems/disorders: Glaucoma	0.9	1.0	1.5	-1.2	-1.1	-1.1	-1.0	-1.1	-1.2	-0.9	-1.1	-0.9	-0.4	-1.1	-0.8	-1.1	-1.1	-0.9	-1.2	-0.8
Medication: Lisinopril	0.9	1.2	2.8	1.3	0.8	0.8	1.5	0.9	0.9	1.1	0.9	0.9	0.7	1.2	1.2	0.9	0.9	1.7	1.0	1.6
Major Depression (MDD)	0.8	0.9	1.3	1.0	1.0	1.1	0.8	1.0	1.2	0.9	1.0	0.9	0.7	1.0	0.9	1.0	1.1	0.8	1.1	0.8
Eye problems/disorders: None of the above	0.8	0.9	1.1	1.0	1.0	0.9	1.0	0.9	0.8	1.0	1.0	1.0	1.0	1.0	0.9	1.0	1.0	1.0	1.0	0.8
Leg fat-free mass (right)	0.8	4.4	8.0	2.7	2.1	2.1	2.2	1.9	2.8	2.1	2.2	2.1	0.4	2.2	1.5	2.3	2.1	1.9	2.1	1.8
Osteoporosis (self-reported)	0.8	1.0	1.7	1.3	1.0	1.0	1.1	0.9	1.3	1.0	1.0	1.0	0.2	1.0	0.7	1.1	1.0	0.9	1.0	0.7
Leg predicted mass (right)	0.8	4.4	8.0	2.7	2.1	2.1	2.2	1.9	2.8	2.1	2.1	2.1	0.4	2.2	1.5	2.3	2.1	1.9	2.1	1.8
Arm fat mass (left)	0.8	3.4	5.1	-1.4	-1.9	-1.9	-1.6	-1.9	-1.4	-1.8	-1.9	-1.8	-2.3	-1.7	-2.0	-1.8	-1.9	-1.7	-1.9	-2.2
Arm fat-free mass (left)	0.8	4.0	5.8	2.3	2.1	2.0	1.9	2.0	2.4	2.0	2.1	2.1	1.2	2.1	1.7	2.1	2.1	1.8	2.0	1.9
Fractured/broken bones in last 5 years	0.8	1.0	2.0	-0.8	-0.8	-0.8	-1.1	-0.9	-0.6	-1.1	-0.9	-1.0	-1.4	-1.0	-1.2	-0.9	-0.9	-1.2	-0.9	-1.2
Heart attack/myocardial infarction (self-reported)	0.8	1.0	2.5	-1.6	-0.8	-0.9	-1.4	-0.8	-1.0	-1.1	-0.9	-0.9	-0.3	-1.0	-0.8	-1.1	-0.9	-1.3	-0.9	-1.0
Ever had hysterectomy (womb removed)	0.7	0.8	1.4	0.7	1.0	1.1	0.6	1.0	0.9	0.8	1.0	0.9	1.0	0.8	0.9	0.9	0.9	0.5	0.9	1.2
Hayfever, allergic rhinitis or eczema	0.7	1.6	3.1	-0.5	-1.3	-1.3	-0.6	-1.4	-1.3	-1.1	-1.3	-1.3	-1.6	-1.2	-1.5	-1.1	-1.3	-0.8	-1.2	-1.8
Qualifications: None of the above	0.7	1.5	4.6	0.5	1.3	1.3	0.8	1.4	0.9	1.2	1.3	1.3	2.1	1.1	1.6	1.1	1.2	1.0	1.1	1.0
Mouth/teeth dental problems: Dentures	0.7	1.2	3.6	-1.9	-0.7	-0.6	-1.7	-0.4	-1.6	-1.1	-0.8	-0.9	0.9	-1.1	-0.3	-1.2	-0.7	-1.5	-0.7	-0.5
Breastfed as a baby	0.7	0.9	2.0	0.8	0.9	0.9	0.9	0.9	1.1	0.9	1.0	1.0	0.6	1.0	0.9	1.0	0.9	0.8	0.9	1.4
Loud music exposure frequency	0.7	0.8	2.0	-1.4	-0.9	-1.0	-1.0	-1.0	-0.7	-0.6	-0.7	-0.5	-0.4	-0.8	-0.7	-0.7	-0.9	-0.9	-1.2	-0.9
Health satisfaction	0.7	1.0	1.2	-0.6	-1.1	-1.1	-0.7	-1.1	-1.0	-1.0	-1.1	-1.1	-1.1	-1.0	-1.0	-1.0	-1.1	-0.7	-1.0	-0.8
Pulse rate, automated reading	0.7	2.3	7.1	2.7	1.4	1.4	2.0	1.2	1.7	1.4	1.4	1.3	-0.4	1.4	0.6	1.7	1.4	1.6	1.5	1.5
Miserableness	0.7	1.1	1.6	-1.1	-1.2	-1.1	-0.8	-1.1	-1.0	-1.0	-1.2	-1.1	-1.0	-1.0	-1.0	-1.1	-1.1	-0.8	-1.1	-1.3
Pain type(s) experienced in last month: Hip pain	0.7	0.8	2.3	-1.5	-0.8	-0.8	-1.2	-0.8	-0.9	-0.9	-0.8	-0.7	-0.1	-0.9	-0.6	-1.0	-0.9	-1.1	-1.0	-0.9
Alcohol drinker status: Previous	0.7	0.8	2.0	1.4	0.9	1.0	1.0	0.9	0.7	0.7	0.8	0.6	0.4	0.8	0.7	0.8	0.9	0.9	1.1	0.7
Leg fat mass (left)	0.7	2.6	3.4	-1.3	-1.7	-1.7	-1.4	-1.7	-1.4	-1.5	-1.7	-1.6	-1.8	-1.5	-1.7	-1.6	-1.7	-1.5	-1.7	-1.8
Bipolar Disorder (2018)	0.6	1.0	1.6	1.3	1.0	1.0	1.3	1.0	1.0	1.0	1.0	0.9	0.5	1.0	0.9	1.0	0.9	1.2	1.0	0.7
Intelligence (Savage-Jansen 2018)	0.6	1.7	2.7	-1.6	-1.4	-1.3	-1.3	-1.4	-1.2	-1.3	-1.3	-1.2	-1.1	-1.3	-1.2	-1.3	-1.4	-1.2	-1.5	-1.2
HbA1C	0.6	0.6	0.9	0.8	0.8	0.8	0.8	0.8	0.9	0.8	0.7	0.7	0.5	0.9	0.9	0.7	0.8	0.9	0.9	0.5
Number of treatments/medications taken	0.6	1.1	2.3	-1.1	-1.1	-1.1	-0.9	-1.0	-1.1	-0.9	-1.1	-1.1	-0.6	-0.9	-0.8	-1.1	-1.1	-0.7	-1.0	-1.5
Severe depression (siblings)	0.6	0.6	1.9	-0.2	-0.9	-0.9	-0.3	-1.0	-0.5	-0.6	-0.8	-0.7	-1.4	-0.7	-1.0	-0.6	-0.9	-0.5	-0.9	-0.8
Relative age voice broke	0.6	0.9	1.6	-0.9	-0.9	-0.9	-1.0	-0.8	-1.3	-1.1	-1.0	-1.1	-0.5	-1.1	-0.8	-1.1	-0.9	-0.9	-0.8	-0.4
Diverticular disease/diverticulitis (self-reported)	0.6	0.8	1.2	-0.9	-0.8	-0.8	-1.0	-0.7	-0.9	-0.9	-0.8	-0.9	-0.6	-0.9	-0.9	-0.9	-0.8	-1.1	-0.8	-1.1
Alcohol intake versus 10 years previously	0.6	0.9	2.7	-1.1	-1.0	-0.9	-0.7	-0.9	-1.3	-0.8	-1.0	-0.9	-0.1	-0.9	-0.5	-1.0	-1.0	-0.5	-0.9	-1.6
Illnesses of father: Heart disease	0.6	0.8	1.7	-1.3	-0.8	-0.8	-1.2	-0.7	-0.8	-0.9	-0.8	-0.8	-0.4	-0.9	-0.7	-0.9	-0.8	-1.1	-0.9	-1.0
Medication: Blood pressure	0.6	1.0	5.9	-0.2	0.9	0.9	0.3	1.1	0.3	0.8	0.9	0.9	2.4	0.8	1.6	0.6	0.8	0.8	0.9	1.0
Arm predicted mass (left)	0.6	2.8	4.1	1.9	1.8	1.7	1.5	1.7	2.0	1.6	1.8	1.7	1.0	1.7	1.5	1.8	1.8	1.4	1.7	1.7
Alzheimer’s Disease (including proxy)	0.5	0.7	1.5	-1.0	-0.7	-0.5	-1.1	-0.7	-0.7	-1.0	-0.7	-0.7	-0.5	-0.9	-0.9	-0.8	-0.8	-1.2	-0.8	-0.9
Hair Pigment	0.5	14.9	18.8	3.6	3.9	3.8	3.6	3.9	3.4	3.9	3.9	3.9	4.2	3.8	4.1	3.8	3.9	3.8	3.9	4.3
Pack years adult smoking proportion	0.5	0.8	1.2	1.0	0.7	0.6	1.0	0.6	1.0	1.0	0.9	1.1	0.6	0.9	0.8	1.0	0.7	1.0	0.6	1.1
Allergy	0.5	1.3	3.5	0.6	1.2	1.2	0.4	1.3	1.0	0.9	1.1	1.0	1.5	1.0	1.3	0.9	1.2	0.6	1.1	1.9
Exposure to tobacco smoke at home	0.5	0.6	1.0	1.0	0.6	0.6	1.0	0.6	0.8	0.8	0.7	0.7	0.3	0.8	0.7	0.8	0.7	0.9	0.7	0.7
Tense / ‘highly strung’	0.5	0.9	1.9	1.0	0.7	0.7	1.2	0.7	1.1	1.0	0.8	0.9	0.3	1.0	0.9	0.9	0.7	1.2	0.8	1.4
Mood swings	0.5	0.8	1.1	0.8	0.9	0.8	0.9	0.9	1.1	1.0	1.0	1.0	0.8	1.0	0.9	1.0	0.9	0.9	0.8	0.5
Ever had bowel cancer screening	0.5	0.5	1.7	-0.1	-0.8	-0.7	-0.2	-0.9	-0.5	-0.6	-0.7	-0.7	-1.3	-0.6	-1.0	-0.5	-0.7	-0.5	-0.7	-1.0
Illnesses of father: None of the above (group 1)	0.5	0.6	0.9	-0.4	-0.8	-0.7	-0.7	-0.8	-1.0	-0.8	-0.8	-0.8	-0.8	-0.9	-0.9	-0.7	-0.8	-0.8	-0.7	-0.2
Mother’s age at death	0.5	0.6	1.6	0.2	0.9	1.0	0.2	0.9	1.3	0.6	0.9	0.9	0.6	0.8	0.8	0.7	0.9	0.2	0.8	0.9
Medication: Atorvastatin	0.5	0.6	1.2	-1.1	-0.9	-0.9	-0.6	-0.9	-0.9	-0.6	-0.9	-0.8	-0.3	-0.7	-0.4	-0.9	-0.9	-0.3	-0.9	-1.1
Basal metabolic rate	0.5	2.6	4.9	2.0	1.7	1.7	1.6	1.6	2.2	1.6	1.7	1.7	0.5	1.7	1.2	1.8	1.7	1.3	1.6	1.3
Commuting to job workplace: Cycle	0.5	0.6	1.3	0.3	0.7	0.6	0.6	0.7	0.8	0.9	0.8	0.9	1.0	0.8	0.9	0.7	0.6	0.7	0.6	1.2
Fasting Glucose	0.4	0.5	1.3	0.7	0.7	0.8	0.8	0.7	1.1	0.7	0.8	0.7	-0.1	0.8	0.5	0.8	0.8	0.7	0.7	0.6
Height	0.4	7.3	13.6	2.8	2.7	2.6	2.6	2.5	3.7	2.7	2.8	2.9	1.0	2.9	2.2	2.9	2.7	2.3	2.6	2.9
Medication: Co-codamol	0.4	0.4	0.9	0.4	0.8	0.9	0.1	0.9	0.4	0.3	0.7	0.4	0.9	0.4	0.6	0.5	0.7	0.1	0.8	0.9
Leg fat-free mass (left)	0.4	2.0	4.5	2.0	1.4	1.4	1.5	1.2	2.1	1.4	1.4	1.4	-0.1	1.5	0.9	1.6	1.4	1.2	1.4	0.9
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.3	0.5	0.7	0.8	0.4	0.8	0.6	0.4	0.7	0.5	0.6	0.6	0.6	0.6	0.7	0.3	0.7	1.1
Sitting height	0.4	3.0	6.0	2.3	1.8	1.8	1.8	1.6	2.4	1.6	1.8	1.7	-0.1	1.8	1.0	2.0	1.8	1.4	1.7	1.6
Leg predicted mass (left)	0.4	2.0	4.5	1.9	1.4	1.4	1.5	1.2	2.1	1.4	1.4	1.4	-0.1	1.5	0.9	1.6	1.4	1.2	1.4	1.0
Alcohol usually taken with meals	0.4	0.7	1.2	0.9	0.7	0.6	1.1	0.6	1.0	1.0	0.8	1.0	0.2	0.9	0.5	1.0	0.7	0.9	0.6	0.4
Hip circumference	0.4	1.8	7.1	-0.6	-1.2	-1.3	-0.9	-1.4	-0.2	-1.1	-1.2	-1.0	-2.7	-1.0	-1.8	-0.9	-1.2	-1.3	-1.4	-1.5
Shortness of breath walking on level ground	0.4	0.5	1.7	0.4	0.7	0.8	0.4	0.8	0.5	0.6	0.7	0.7	1.3	0.7	0.9	0.6	0.7	0.6	0.7	0.3
Emphysema/chronic bronchitis	0.4	0.4	0.7	0.8	0.6	0.7	0.8	0.7	0.6	0.6	0.6	0.5	0.6	0.7	0.7	0.6	0.6	0.8	0.7	0.5
Medication for pain relief, constipation, heartburn	0.4	0.6	1.6	1.3	0.6	0.7	1.1	0.5	0.5	0.8	0.6	0.6	0.4	0.7	0.6	0.8	0.6	1.0	0.7	1.1
Knee pain experienced in last month	0.4	0.6	1.3	-1.2	-0.8	-0.7	-1.0	-0.7	-0.6	-0.8	-0.7	-0.6	-0.3	-0.7	-0.6	-0.8	-0.8	-0.9	-0.9	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.7	-1.3	-0.6	-0.6	-1.0	-0.5	-0.9	-0.7	-0.6	-0.6	0.2	-0.7	-0.3	-0.8	-0.6	-0.8	-0.7	-0.4
Loneliness, isolation	0.4	0.5	1.8	0.5	0.6	0.6	0.7	0.8	0.2	0.7	0.6	0.5	1.3	0.7	1.1	0.5	0.6	1.0	0.8	0.7
Medication: Bendroflumethiazide	0.4	0.6	1.0	-0.7	-0.7	-0.6	-1.0	-0.6	-1.0	-0.9	-0.8	-0.9	-0.3	-0.9	-0.7	-0.9	-0.8	-0.9	-0.7	-0.7
Ever depressed for a whole week	0.4	0.4	1.0	0.8	0.6	0.6	0.8	0.6	1.0	0.7	0.7	0.7	0.0	0.8	0.5	0.8	0.7	0.7	0.6	0.1
Bipolar Disorder or Schizophrenia	0.3	0.9	1.4	1.2	0.8	1.0	1.2	0.9	1.2	0.9	0.8	0.7	0.0	1.0	0.7	0.9	0.8	1.1	1.0	0.6
Depressed Affect (Nagel 2018)	0.3	0.5	1.0	0.3	0.8	0.7	0.4	0.8	0.7	0.7	0.8	0.7	1.0	0.7	0.9	0.6	0.7	0.6	0.7	0.7
Schizophrenia vs Biploar Disorder	0.3	0.4	0.9	0.4	0.8	0.9	0.0	1.0	0.9	0.4	0.7	0.5	0.4	0.6	0.6	0.5	0.7	0.0	0.8	0.6
Sensitivity / hurt feelings	0.3	0.4	0.6	-0.8	-0.7	-0.6	-0.6	-0.7	-0.7	-0.7	-0.7	-0.8	-0.6	-0.7	-0.6	-0.8	-0.7	-0.6	-0.6	-0.4
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.4	-1.1	-0.1	0.0	-1.2	0.0	-0.5	-0.6	-0.2	-0.4	0.6	-0.5	-0.0	-0.6	-0.2	-1.0	-0.2	0.9
Supplements: Zinc	0.3	0.3	1.1	0.3	0.5	0.6	0.3	0.5	0.9	0.4	0.5	0.5	-0.1	0.5	0.4	0.5	0.5	0.2	0.5	1.0
Hearing difficulty/problems with background noise	0.3	0.6	1.2	0.4	0.7	0.6	0.8	0.6	0.7	0.9	0.8	0.9	1.1	0.8	0.9	0.8	0.6	0.8	0.5	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.1	0.5	0.8	0.7	0.9	0.8	1.0	1.0	0.9	0.9	0.8	1.0	0.9	0.9	0.8	1.0	0.8	0.4
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	1.1	-0.2	-0.7	-0.7	-0.2	-0.7	-0.5	-0.4	-0.6	-0.5	-0.6	-0.5	-0.6	-0.4	-0.7	-0.3	-0.7	-1.0
Length of working week for main job	0.3	0.3	0.9	-0.1	-0.7	-0.7	-0.1	-0.7	-1.0	-0.4	-0.7	-0.6	-0.3	-0.6	-0.4	-0.6	-0.7	-0.0	-0.6	-0.4
Blood clot in the leg (DVT)	0.3	0.4	0.8	0.8	0.5	0.5	0.9	0.4	0.6	0.8	0.6	0.8	0.5	0.7	0.6	0.8	0.5	0.8	0.4	0.1
Exposure to tobacco smoke outside home	0.3	0.4	1.0	-1.0	-0.6	-0.7	-0.7	-0.6	-0.8	-0.6	-0.6	-0.5	0.1	-0.6	-0.3	-0.7	-0.7	-0.5	-0.7	-0.6
Number of children fathered	0.3	0.3	0.7	0.6	0.6	0.5	0.5	0.5	0.9	0.5	0.6	0.5	-0.3	0.6	0.2	0.6	0.6	0.4	0.6	0.4
Comparative height size at age 10	0.3	1.6	3.9	-2.0	-1.1	-1.1	-1.7	-1.1	-0.7	-1.2	-1.1	-1.0	-1.0	-1.1	-1.1	-1.3	-1.2	-1.6	-1.3	-1.3
Had major operations	0.3	0.4	0.8	-0.4	-0.6	-0.6	-0.5	-0.7	-0.6	-0.7	-0.6	-0.6	-0.9	-0.6	-0.8	-0.6	-0.6	-0.6	-0.6	-0.3
Age at last live birth	0.3	0.4	2.7	0.2	-0.7	-0.6	-0.1	-0.8	-0.2	-0.6	-0.7	-0.7	-1.6	-0.5	-0.9	-0.5	-0.6	-0.3	-0.5	-0.3
Back pain experienced in last month	0.3	0.4	0.6	0.5	0.6	0.7	0.5	0.7	0.8	0.6	0.6	0.6	0.5	0.7	0.7	0.6	0.6	0.5	0.7	0.6
Osteoarthritis (self-reported)	0.3	0.4	2.0	-0.2	0.5	0.5	0.2	0.6	0.4	0.6	0.6	0.8	1.4	0.5	0.9	0.5	0.5	0.4	0.4	1.0
Medication: Gliclazide	0.3	0.3	0.7	-0.4	-0.6	-0.5	-0.4	-0.7	-0.3	-0.4	-0.5	-0.3	-0.7	-0.5	-0.7	-0.4	-0.6	-0.5	-0.7	-0.8
Number of self-reported non-cancer illnesses	0.3	0.5	1.3	-1.1	-0.7	-0.8	-0.7	-0.7	-0.6	-0.5	-0.7	-0.5	-0.3	-0.6	-0.4	-0.7	-0.7	-0.5	-0.8	-0.9
Illnesses of father: High blood pressure	0.3	0.3	0.8	0.8	0.5	0.6	0.6	0.6	0.6	0.4	0.5	0.3	0.1	0.6	0.5	0.4	0.6	0.6	0.7	0.9
Diastolic blood pressure, automated reading	0.3	0.9	1.9	1.3	0.8	0.8	1.4	0.8	1.0	1.1	0.9	0.9	0.3	1.1	0.8	1.0	0.9	1.3	0.9	0.3
Heart disease (siblings)	0.3	0.4	1.3	-1.1	-0.2	-0.2	-1.1	-0.0	-0.7	-0.6	-0.3	-0.5	0.7	-0.6	-0.0	-0.7	-0.3	-0.9	-0.3	0.1
Reaction Time	0.2	0.5	0.9	0.7	0.7	0.6	0.6	0.7	0.4	0.8	0.8	0.8	0.9	0.6	0.6	0.8	0.7	0.6	0.6	0.5
Breast Cancer	0.2	0.4	2.2	1.5	0.3	0.2	1.0	0.2	0.8	0.4	0.3	0.2	-1.2	0.5	-0.2	0.6	0.4	0.7	0.5	-0.5
Bipolar Disorder (2011)	0.2	0.2	0.3	0.3	0.5	0.5	0.2	0.5	0.4	0.4	0.4	0.3	0.5	0.4	0.5	0.4	0.5	0.3	0.5	0.3
Rheumatoid Arthritis	0.2	0.2	0.5	-0.6	-0.6	-0.6	-0.3	-0.5	-0.7	-0.3	-0.6	-0.5	0.1	-0.4	-0.1	-0.6	-0.6	-0.1	-0.5	-0.5
Waist Hip Ratio (WHR)	0.2	0.9	3.6	-1.3	-0.9	-0.9	-0.8	-0.6	-1.9	-0.8	-0.9	-1.0	1.1	-0.9	0.1	-1.1	-0.8	-0.3	-0.7	-0.4
Medication for hormone replacement therapy	0.2	0.3	0.6	0.4	0.7	0.7	0.1	0.7	0.6	0.2	0.6	0.4	0.3	0.4	0.4	0.4	0.6	0.0	0.7	0.8
Maternal smoking around birth	0.2	0.3	1.0	0.5	0.5	0.5	0.5	0.4	1.0	0.6	0.6	0.7	0.0	0.7	0.4	0.7	0.5	0.4	0.4	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.3	-1.1	-0.6	-0.7	-0.8	-0.5	-0.9	-0.6	-0.6	-0.6	0.0	-0.6	-0.4	-0.7	-0.6	-0.6	-0.6	-0.8
Stomach or abdominal pain in last month	0.2	0.2	1.8	0.7	-0.2	-0.1	0.3	-0.3	0.3	-0.2	-0.2	-0.3	-1.4	-0.1	-0.6	-0.0	-0.1	-0.0	-0.1	-0.5
Waist circumference	0.2	0.7	1.2	-0.6	-0.9	-1.0	-0.6	-1.0	-0.7	-0.7	-0.9	-0.8	-0.9	-0.7	-0.8	-0.8	-0.9	-0.6	-1.0	-1.1
Illnesses of siblings	0.2	0.3	1.4	0.1	-0.5	-0.5	-0.1	-0.6	-0.2	-0.4	-0.5	-0.5	-1.2	-0.4	-0.8	-0.3	-0.4	-0.3	-0.4	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.6	0.0	0.6	0.6	0.2	0.6	0.8	0.4	0.6	0.6	0.5	0.5	0.6	0.4	0.5	0.2	0.5	0.7
Asthma	0.2	0.5	1.2	0.6	0.5	0.4	1.0	0.4	1.1	0.9	0.6	0.8	-0.1	0.8	0.4	0.8	0.5	0.9	0.5	0.0
Illnesses of mother	0.2	0.2	1.3	0.9	0.3	0.3	0.2	0.1	0.6	0.0	0.2	0.1	-1.1	0.1	-0.5	0.4	0.3	-0.1	0.3	-0.0
Pulse wave Arterial Stiffness index	0.2	0.3	0.5	0.7	0.5	0.6	0.6	0.5	0.5	0.5	0.5	0.4	0.2	0.6	0.5	0.5	0.6	0.6	0.6	0.7
Medication: Paracetamol	0.2	0.4	0.9	0.5	0.9	0.9	0.2	0.9	0.8	0.4	0.8	0.6	0.4	0.6	0.5	0.6	0.8	0.1	0.8	0.4
Medication: Omeprazole	0.2	0.3	0.6	-0.7	-0.6	-0.6	-0.5	-0.5	-0.7	-0.3	-0.5	-0.4	0.1	-0.5	-0.2	-0.5	-0.6	-0.3	-0.6	-0.8
Alcohol intake frequency.	0.2	0.6	0.8	-0.7	-0.7	-0.7	-0.8	-0.7	-0.7	-0.8	-0.7	-0.7	-0.7	-0.8	-0.8	-0.7	-0.7	-0.9	-0.7	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.7	0.1	-0.5	-0.6	0.1	-0.5	-0.8	-0.2	-0.5	-0.4	-0.2	-0.4	-0.3	-0.3	-0.5	0.2	-0.4	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	1.5	-0.2	-0.6	-0.6	-0.2	-0.6	-0.3	-0.5	-0.6	-0.6	-1.2	-0.4	-0.7	-0.5	-0.5	-0.2	-0.5	-0.8
Average weekly red wine intake	0.2	0.2	0.7	0.5	0.4	0.3	0.8	0.3	0.6	0.6	0.4	0.5	0.1	0.6	0.4	0.6	0.4	0.8	0.4	-0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.4	-0.4	-0.4	-0.5	-0.6	-0.4	-0.4	-0.4	-0.4	-0.4	-0.3	-0.5	-0.4	-0.4	-0.4	-0.6	-0.5	-0.1
Asthma (self-reported)	0.2	0.3	0.9	0.6	0.3	0.3	0.9	0.2	0.9	0.8	0.5	0.7	-0.2	0.7	0.3	0.7	0.3	0.9	0.3	-0.1
Vascular/heart problems diagnosed by doctor	0.2	0.4	1.6	1.2	0.5	0.5	0.6	0.3	1.0	0.4	0.5	0.4	-1.0	0.4	-0.2	0.7	0.5	0.2	0.5	0.8
Schizophrenia (2018)	0.1	0.2	0.5	0.5	0.3	0.5	0.5	0.4	0.7	0.3	0.3	0.2	-0.4	0.5	0.3	0.3	0.3	0.5	0.5	0.2
Worry (Nagel 2018)	0.1	0.2	0.8	-0.1	-0.5	-0.5	0.1	-0.5	-0.1	-0.2	-0.5	-0.4	-0.9	-0.2	-0.4	-0.3	-0.5	0.1	-0.4	-0.6
Alzheimer’s Disease (in father)	0.1	0.1	0.1	0.4	0.4	0.3	0.3	0.4	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.3	0.2	0.4	0.4
Ovarian Cancer	0.1	0.1	0.7	-0.8	-0.2	-0.1	-0.5	-0.0	-0.5	-0.3	-0.2	-0.2	0.7	-0.2	0.2	-0.4	-0.2	-0.2	-0.2	-0.1
HDL Cholesterol	0.1	0.2	0.7	-0.6	-0.4	-0.3	-0.8	-0.4	-0.5	-0.6	-0.4	-0.4	-0.1	-0.5	-0.4	-0.5	-0.4	-0.8	-0.4	-0.2
Neuroticism (2016)	0.1	0.1	1.2	0.1	-0.3	-0.3	0.1	-0.4	0.3	-0.2	-0.3	-0.2	-1.1	-0.1	-0.5	-0.1	-0.3	-0.1	-0.4	-0.4
Blood Red Count	0.1	0.9	2.1	-0.7	-0.6	-0.4	-1.4	-0.5	-1.1	-1.2	-0.7	-1.1	-0.6	-1.1	-1.0	-1.0	-0.6	-1.5	-0.5	-1.0
Respiratory disease	0.1	0.2	0.8	0.4	0.4	0.4	0.6	0.3	0.9	0.6	0.5	0.7	-0.2	0.6	0.2	0.6	0.4	0.5	0.3	-0.1
Type 2 Diabetes (T2D) (2018)	0.1	0.2	1.1	-0.6	-0.6	-0.6	-0.2	-0.6	-0.4	-0.2	-0.5	-0.3	-0.1	-0.3	-0.2	-0.4	-0.5	-0.1	-0.6	-1.1
Average weekly spirits intake	0.1	0.2	1.0	0.5	0.2	0.2	0.5	0.2	0.4	0.4	0.3	0.3	0.0	0.3	0.3	0.3	0.2	0.4	0.2	1.0
Relative age of first facial hair	0.1	0.2	0.4	-0.4	-0.6	-0.6	-0.4	-0.6	-0.4	-0.4	-0.5	-0.4	-0.6	-0.5	-0.6	-0.4	-0.6	-0.4	-0.6	-0.2
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.2	0.5	0.1	0.2	0.4	0.0	0.4	0.2	0.2	0.2	-0.4	0.2	-0.1	0.3	0.2	0.2	0.1	0.5
Medication: Metformin	0.1	0.2	1.0	-0.4	-0.4	-0.3	-0.3	-0.3	-0.3	-0.3	-0.4	-0.4	-0.3	-0.3	-0.3	-0.4	-0.4	-0.2	-0.4	-1.0
Fed-up feelings	0.1	0.1	0.4	0.2	0.3	0.4	0.4	0.4	0.2	0.3	0.3	0.2	0.6	0.4	0.6	0.2	0.3	0.5	0.4	0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	1.2	0.5	-0.2	-0.2	0.1	-0.2	0.2	-0.2	-0.2	-0.2	-1.1	-0.1	-0.5	-0.0	-0.2	-0.2	-0.1	0.0
High blood pressure	0.1	0.2	1.9	-0.6	-0.1	-0.1	-0.1	0.1	-0.5	0.1	-0.0	0.0	1.4	0.1	0.7	-0.2	-0.1	0.4	0.0	-0.5
Medication: Atenolol	0.1	0.2	0.6	-0.4	-0.2	-0.1	-0.7	-0.0	-0.8	-0.5	-0.3	-0.4	0.6	-0.5	-0.0	-0.5	-0.2	-0.5	-0.1	-0.2
High blood pressure (mother)	0.1	0.1	1.0	-0.1	0.2	0.2	0.2	0.3	-0.1	0.3	0.2	0.2	1.0	0.3	0.7	0.1	0.2	0.5	0.2	0.4
Body mass index (BMI)	0.1	0.6	1.1	-0.3	-0.8	-0.8	-0.6	-0.8	-0.6	-0.7	-0.8	-0.8	-1.0	-0.7	-0.9	-0.7	-0.8	-0.6	-0.8	-1.0
Number of incorrect matches in round	0.1	0.1	0.7	0.2	0.3	0.3	0.1	0.3	0.0	0.2	0.3	0.3	0.6	0.1	0.3	0.3	0.2	0.0	0.2	0.8
Past tobacco smoking	0.1	0.2	0.5	-0.6	-0.4	-0.3	-0.7	-0.3	-0.6	-0.6	-0.5	-0.6	-0.3	-0.5	-0.4	-0.6	-0.4	-0.6	-0.3	0.3
Had menopause	0.1	0.2	0.8	-0.9	-0.1	0.0	-0.7	0.0	-0.1	-0.3	-0.0	0.0	0.6	-0.2	0.1	-0.3	-0.1	-0.6	-0.2	0.5
Pain all over the body in last month	0.1	0.1	0.5	-0.7	-0.4	-0.5	-0.5	-0.4	-0.3	-0.3	-0.3	-0.2	-0.0	-0.4	-0.3	-0.4	-0.4	-0.4	-0.5	-0.0
Fluid intelligence score	0.1	0.2	0.4	0.3	0.4	0.4	0.4	0.4	0.4	0.3	0.3	0.2	0.3	0.4	0.4	0.3	0.4	0.4	0.4	0.7
Hair/balding pattern: Pattern 3	0.1	0.1	0.6	0.1	-0.3	-0.2	-0.0	-0.3	-0.4	-0.3	-0.4	-0.4	-0.5	-0.3	-0.4	-0.2	-0.3	-0.1	-0.2	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.5	-0.2	0.3	0.2	0.0	0.3	0.2	0.3	0.3	0.4	0.7	0.3	0.4	0.2	0.3	0.1	0.2	-0.1
Standing height	0.1	0.7	2.5	0.9	0.8	0.7	0.8	0.7	1.6	0.8	0.9	1.0	-0.5	1.0	0.4	1.0	0.8	0.6	0.7	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	1.1	-1.1	-0.4	-0.4	-0.3	-0.4	-0.1	-0.0	-0.2	0.0	0.3	-0.1	0.1	-0.3	-0.4	-0.1	-0.5	-0.5
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.7	0.1	-0.2	-0.2	-0.2	-0.3	-0.1	-0.3	-0.3	-0.4	-0.8	-0.2	-0.5	-0.3	-0.2	-0.3	-0.2	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.4	0.2	0.2	0.1	0.7	0.1	0.5	0.6	0.3	0.5	0.1	0.5	0.4	0.4	0.2	0.6	0.1	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.4	0.7	0.3	0.3	0.5	0.3	0.3	0.3	0.2	0.2	-0.1	0.3	0.2	0.3	0.3	0.5	0.4	0.1
Age at first live birth	0.1	0.2	1.1	-0.0	-0.5	-0.4	-0.1	-0.6	-0.2	-0.4	-0.5	-0.6	-1.0	-0.4	-0.5	-0.4	-0.5	-0.1	-0.4	0.3
Pulse wave peak to peak time	0.1	0.1	0.2	-0.4	-0.3	-0.3	-0.4	-0.3	-0.3	-0.3	-0.2	-0.2	-0.2	-0.3	-0.3	-0.2	-0.3	-0.4	-0.3	-0.5
Migraine (self-reported)	0.1	0.1	0.2	0.0	0.4	0.4	-0.2	0.4	0.2	0.0	0.3	0.1	0.3	0.1	0.1	0.1	0.3	-0.2	0.4	-0.4
Medication: Allopurinol	0.1	0.1	0.2	-0.4	-0.4	-0.3	-0.3	-0.3	-0.5	-0.4	-0.4	-0.4	-0.0	-0.3	-0.1	-0.5	-0.4	-0.2	-0.3	-0.2
Medication: Seretide 50 evohaler	0.1	0.1	0.2	-0.3	0.3	0.2	-0.2	0.2	0.3	0.2	0.3	0.4	0.4	0.2	0.2	0.2	0.2	-0.2	0.1	0.0
Mean time to correctly identify matches	0.1	0.2	0.4	0.4	0.4	0.3	0.5	0.3	0.2	0.6	0.5	0.6	0.7	0.4	0.4	0.6	0.4	0.5	0.3	0.1
Heart disease (mother)	0.1	0.1	0.4	0.1	0.3	0.2	0.3	0.3	0.2	0.4	0.3	0.3	0.6	0.4	0.5	0.3	0.3	0.5	0.3	0.3
Suffer from ‘nerves’	0.1	0.2	0.6	-0.1	-0.6	-0.6	0.2	-0.6	-0.3	-0.2	-0.5	-0.4	-0.8	-0.2	-0.4	-0.4	-0.5	0.2	-0.5	-0.7
Hypertension (Self-reported)	0.1	0.2	1.8	-0.6	0.0	0.1	-0.0	0.2	-0.4	0.2	0.1	0.1	1.3	0.1	0.7	-0.1	0.0	0.4	0.1	-0.2
Smoking status: Previous	0.1	0.1	0.5	-0.1	-0.3	-0.3	-0.0	-0.3	0.0	-0.1	-0.2	-0.1	-0.4	-0.1	-0.3	-0.1	-0.2	-0.1	-0.3	-0.7
Friendships satisfaction	0.1	0.1	0.6	0.5	-0.0	-0.1	0.7	-0.0	-0.2	0.3	0.0	0.1	0.3	0.2	0.3	0.2	0.1	0.7	0.1	0.3
Qualifications: nursing, teaching	0.1	0.2	0.5	-0.3	-0.5	-0.5	-0.2	-0.6	-0.2	-0.3	-0.5	-0.4	-0.7	-0.3	-0.5	-0.3	-0.5	-0.2	-0.5	-0.7
Eye problems/disorders: Cataract	0.1	0.1	0.2	-0.5	-0.3	-0.2	-0.4	-0.2	-0.3	-0.3	-0.3	-0.3	-0.1	-0.3	-0.2	-0.3	-0.3	-0.3	-0.3	-0.1
Wears glasses or contact lenses	0.1	0.1	0.3	-0.5	-0.4	-0.3	-0.5	-0.4	-0.3	-0.4	-0.3	-0.3	-0.2	-0.4	-0.4	-0.4	-0.4	-0.5	-0.5	-0.2
Hearing aid user	0.1	0.2	0.2	-0.4	-0.4	-0.5	-0.3	-0.4	-0.5	-0.4	-0.5	-0.5	-0.3	-0.4	-0.3	-0.5	-0.4	-0.3	-0.4	0.2
Financial situation satisfaction	0.1	0.2	0.9	1.0	0.2	0.3	0.7	0.2	0.2	0.3	0.2	0.1	-0.1	0.3	0.2	0.3	0.3	0.7	0.4	-0.0
Tinnitus: Yes, now most or all of the time	0.1	0.1	1.1	0.4	-0.2	-0.2	0.2	-0.2	0.2	-0.1	-0.2	-0.2	-1.1	-0.1	-0.4	-0.0	-0.1	0.0	-0.1	0.2
High cholesterol (Self-reported)	0.1	0.2	1.3	-1.1	-0.2	-0.2	-1.0	-0.1	-0.1	-0.4	-0.2	-0.1	0.2	-0.3	-0.1	-0.4	-0.3	-0.9	-0.4	-0.1
Medication: Paracetamol	0.1	0.2	0.4	0.5	0.6	0.6	0.3	0.6	0.5	0.4	0.5	0.4	0.3	0.5	0.4	0.4	0.6	0.3	0.6	0.3
Average weekly beer plus cider intake	0.1	0.2	0.4	-0.3	-0.2	-0.2	-0.6	-0.1	-0.5	-0.6	-0.3	-0.5	-0.3	-0.5	-0.4	-0.5	-0.2	-0.6	-0.2	-0.5
Cholesterol lowering medication	0.1	0.2	0.9	-1.0	-0.3	-0.3	-0.7	-0.2	-0.3	-0.3	-0.2	-0.2	0.3	-0.3	-0.0	-0.4	-0.4	-0.5	-0.4	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.3	0.4	0.1	0.2	0.5	0.1	0.3	0.4	0.2	0.4	0.1	0.3	0.2	0.4	0.2	0.4	0.1	-0.2
Neuroticism (Nagel 2018)	0.0	0.1	0.3	0.1	0.1	0.1	0.4	0.2	0.4	0.4	0.2	0.2	0.1	0.4	0.3	0.2	0.1	0.6	0.2	0.3
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.4	-0.6	-0.3	-0.2	-0.4	-0.2	-0.3	-0.3	-0.3	-0.4	-0.2	-0.2	-0.1	-0.4	-0.3	-0.3	-0.3	-0.2
Age at First Birth	0.0	0.1	0.2	0.1	0.2	0.3	0.2	0.2	0.5	0.3	0.2	0.4	0.0	0.3	0.1	0.3	0.2	0.1	0.2	0.2
Lupus	0.0	0.1	0.5	0.1	-0.2	-0.2	0.4	-0.3	0.4	0.2	-0.1	0.1	-0.7	0.2	-0.1	0.0	-0.1	0.4	-0.2	0.0
Triglycerides	0.0	0.0	0.1	-0.4	-0.1	-0.0	-0.3	-0.1	-0.2	-0.2	-0.1	-0.2	0.1	-0.2	-0.1	-0.2	-0.1	-0.3	-0.2	0.0
Cardiovascular Disease	0.0	0.1	0.7	-0.9	-0.2	-0.2	-0.5	0.0	-0.4	-0.2	-0.2	-0.3	0.7	-0.1	0.4	-0.5	-0.2	-0.1	-0.1	-0.1
Neuroticism	0.0	0.1	0.2	0.2	0.1	0.1	0.4	0.2	0.4	0.3	0.2	0.2	-0.1	0.3	0.2	0.2	0.2	0.5	0.2	-0.1
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.2	-0.4	-0.1	-0.2	0.0	-0.1	0.1	0.2	-0.0	0.2	0.3	0.1	0.2	-0.0	-0.1	0.1	-0.2	0.1
Diabetes (father)	0.0	0.0	0.5	0.2	-0.1	0.0	-0.0	-0.1	0.2	-0.2	-0.1	-0.3	-0.7	-0.0	-0.2	-0.1	-0.0	-0.1	0.0	-0.1
Townsend deprivation index at recruitment	0.0	0.1	0.4	-0.3	-0.1	-0.3	0.0	-0.1	-0.3	0.2	-0.0	0.2	0.7	-0.0	0.3	-0.0	-0.1	0.2	-0.2	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.0	0.3	0.0	0.1	-0.0	0.2	0.1	0.0	0.3	0.1	0.2	0.6	0.2	0.4	0.1	0.1	0.3	0.0	0.2
Taking other prescription medications	0.0	0.0	0.1	-0.2	0.1	0.1	-0.1	0.1	0.2	0.0	0.1	0.1	0.1	0.1	0.1	0.0	0.0	-0.1	0.0	-0.1
Nervous feelings	0.0	0.1	0.4	0.4	0.0	0.0	0.6	0.0	0.0	0.3	0.1	0.1	0.1	0.2	0.3	0.2	0.1	0.7	0.1	0.2
Medication: Simvastatin	0.0	0.1	0.2	0.1	0.2	0.2	0.2	0.2	0.4	0.2	0.2	0.3	-0.0	0.3	0.1	0.3	0.2	0.2	0.2	-0.2
Neuroticism score	0.0	0.1	0.4	0.0	-0.4	-0.3	0.1	-0.4	-0.2	-0.2	-0.4	-0.4	-0.6	-0.2	-0.3	-0.3	-0.4	0.1	-0.2	-0.2
Weight	0.0	0.2	1.2	0.1	-0.3	-0.3	-0.1	-0.4	0.2	-0.2	-0.3	-0.2	-1.1	-0.2	-0.6	-0.2	-0.3	-0.3	-0.3	-0.6
Falls in the last year	0.0	0.0	0.1	-0.1	-0.1	-0.1	-0.1	-0.1	0.2	-0.0	-0.0	0.0	-0.3	-0.0	-0.2	-0.0	-0.1	-0.1	-0.1	-0.1
Pulse wave reflection index	0.0	0.0	0.2	0.1	-0.1	-0.1	0.3	-0.1	-0.2	0.1	-0.1	-0.0	0.3	0.1	0.2	-0.0	-0.0	0.4	-0.0	-0.5
Ever highly irritable/argumentative for 2 days	0.0	0.0	0.3	0.2	0.2	0.2	-0.1	0.2	-0.2	-0.1	0.1	-0.1	0.3	-0.0	0.1	-0.0	0.2	-0.1	0.2	0.5
Gout (self-reported)	0.0	0.0	0.1	0.1	-0.0	0.1	0.1	0.1	-0.1	-0.0	-0.0	-0.1	0.1	0.1	0.2	-0.1	-0.0	0.2	0.2	0.1
Medication: Amlodipine	0.0	0.0	0.3	-0.5	-0.1	-0.1	-0.1	-0.0	-0.2	0.0	-0.0	0.0	0.5	-0.0	0.2	-0.1	-0.1	0.1	-0.1	-0.1
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.1	0.0	0.1	0.2	0.0	0.1	0.3	0.0	0.1	0.1	-0.1	0.1	0.1	0.1	0.1	0.0	0.1	0.1
Overall health rating	0.0	0.1	0.4	-0.6	-0.2	-0.1	-0.3	-0.1	-0.4	-0.2	-0.2	-0.2	0.5	-0.2	0.2	-0.3	-0.2	-0.1	-0.1	-0.4
Chest pain or discomfort	0.0	0.0	0.1	-0.3	0.1	-0.0	-0.2	0.1	0.2	0.0	0.1	0.1	0.0	0.1	0.1	-0.0	0.1	-0.1	0.0	-0.0
Alcohol drinker status: Never	0.0	0.1	0.3	-0.0	0.2	0.2	-0.4	0.2	0.2	-0.2	0.1	-0.1	-0.2	-0.1	-0.1	-0.0	0.2	-0.5	0.1	0.5
Ever smoked	0.0	0.1	0.2	0.3	0.2	0.1	0.4	0.1	0.3	0.4	0.2	0.3	0.0	0.3	0.1	0.3	0.2	0.4	0.1	-0.1
Irritability	0.0	0.1	0.2	0.1	-0.2	-0.1	-0.1	-0.2	-0.2	-0.3	-0.2	-0.3	-0.4	-0.2	-0.3	-0.2	-0.2	-0.2	-0.1	-0.4
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.1	0.1	0.1	0.0	0.1	0.0	0.1	0.1	0.1	0.2	0.1	0.1	0.0	0.2	0.1	-0.0	0.0	0.3
Unable to work because of sickness or disability	0.0	0.1	0.2	-0.0	0.1	0.1	0.2	0.1	0.2	0.4	0.2	0.4	0.4	0.3	0.3	0.3	0.1	0.3	-0.0	0.2

Hub : Genes

HORMAD1

Models

Trait associations