Hub : Genes

IARS

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0710	0.0320	3.4e-03	0.018	0.018	0.008	0.025	0.024	2.4e-03	2.7e-03	3.0e-02	3.9e-04	5.5e-04
2	GTEx	Brain Cerebellum	0.2680	0.1060	3.1e-03	-0.007	NA	0.006	NA	-0.001	6.1e-01	NA	2.1e-01	NA	3.3e-01
3	GTEx	Cells Transformed fibroblasts	0.1430	0.0470	2.1e-04	0.011	NA	0.073	NA	0.034	4.6e-02	NA	3.8e-06	NA	1.3e-03
4	GTEx	Muscle Skeletal	0.1353	0.0450	6.4e-04	-0.002	NA	-0.003	NA	0.062	5.2e-01	NA	9.6e-01	NA	9.7e-07
5	METSIM	Adipose	0.0508	0.0203	7.9e-04	0.027	0.026	0.045	0.030	0.037	4.6e-05	7.0e-05	2.3e-07	1.9e-05	2.3e-06
6	NTR	Blood	0.0690	0.0182	7.7e-14	0.051	0.053	0.044	0.051	0.048	5.4e-16	1.1e-16	3.7e-14	3.3e-16	2.5e-15
7	YFS	Blood	0.0218	0.0086	1.4e-04	0.004	0.007	0.003	0.009	0.008	1.3e-02	1.5e-03	2.4e-02	3.8e-04	7.0e-04
8	TCGA	Breast Invasive Carcinoma	0.0215	0.0139	5.6e-03	0.005	0.009	0.002	NA	0.001	2.7e-02	5.3e-03	9.7e-02	NA	1.7e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.5	0.8	2.4	0.4	-0.7	-0.0	0.2	0.8	0.3	1.5	1.6
Bipolar Disorder or Schizophrenia	0.6	1.5	7.1	-1.2	-2.7	0.1	1.0	-0.8	-1.3	0.6	0.2
Depressed Affect (Nagel 2018)	1.1	2.2	5.7	-1.9	-0.8	0.2	0.8	-0.8	-2.4	-1.5	-2.1
Depression (Nagel 2018)	0.2	0.4	1.2	0.2	0.5	-0.1	-1.1	0.8	-0.7	0.1	-0.5
Intelligence (Savage-Jansen 2018)	0.4	1.3	2.9	1.4	-0.2	0.4	0.1	1.2	1.7	1.1	1.7
Neuroticism (Nagel 2018)	1.0	2.3	5.3	-2.3	-0.3	1.0	1.1	-0.4	-2.1	-1.7	-1.9
Schizophrenia (2018)	1.2	2.5	7.8	-1.8	-2.8	0.1	1.2	-1.6	-2.0	-0.5	-0.9
Schizophrenia vs Biploar Disorder	0.6	0.8	2.5	0.5	0.9	-0.2	-1.6	-1.6	0.1	-0.2	-0.8
Worry (Nagel 2018)	0.5	1.0	2.8	-1.7	0.1	0.2	1.1	-0.4	-1.0	-1.2	-1.0
Alzheimer’s Disease (in mother)	1.6	1.9	6.1	2.5	1.2	0.8	-1.6	0.7	1.4	1.1	1.1
Alzheimer’s Disease (in father)	0.8	0.9	2.9	0.9	0.8	-0.5	-0.9	0.6	0.3	1.7	1.3
Alzheimer’s Disease (including proxy)	1.9	2.8	8.1	2.9	1.4	0.1	-2.1	0.2	1.6	1.9	1.4
Crohns Disease (2017)	0.4	0.9	4.0	2.0	-0.3	-1.0	-0.5	-1.0	-0.2	0.6	0.7
Irritable Bowel Disease (IBD)	0.4	0.9	3.1	1.8	0.3	-1.5	-0.5	-0.6	-0.8	-0.0	0.4
Ulcerative Colitis (UC)	0.5	0.9	2.5	0.3	0.5	-1.5	-0.1	-0.5	-1.6	-1.3	-0.7
Major Depression (MDD)	0.1	0.1	0.2	-0.3	-0.0	0.3	-0.1	0.2	0.1	0.5	0.4
Reaction Time	0.4	0.7	2.8	0.4	0.5	1.7	-1.4	0.5	0.1	0.2	0.2
Verbal and Numeric Reasoning (VNR)	1.3	3.2	8.5	1.9	0.7	0.5	0.5	1.9	2.9	1.6	2.4
Breast Cancer	0.1	0.3	0.8	0.9	0.4	-0.7	-0.3	0.8	-0.4	0.0	-0.6
Ovarian Cancer	0.7	1.0	3.3	-0.1	1.1	0.9	-0.2	0.1	1.8	0.9	1.2
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.5	0.8	2.1	-0.3	1.0	-0.6	1.5	-1.2	-0.1	-0.9	-0.6
Bipolar Disorder (2011)	1.2	1.2	2.8	1.4	-0.6	0.7	-0.2	0.5	1.0	1.7	1.5
Body Mass Index (BMI) (2010)	0.7	1.0	1.6	1.2	0.9	0.5	-0.1	1.2	1.3	1.1	1.2
Coronary Artery Disease (CAD)	0.3	0.4	1.1	-0.0	0.8	0.1	0.3	-0.6	-0.1	-0.8	-1.0
Crohns Disease (2012)	0.4	0.6	2.8	1.7	0.3	-0.9	0.3	-1.1	0.0	0.0	-0.0
Mean Putamen Volume	1.6	1.9	4.2	2.1	-0.6	1.0	0.5	1.6	1.9	1.0	1.5
Fasting Glucose	0.5	0.6	2.5	0.2	-0.9	0.2	0.9	0.3	0.5	0.8	1.6
HbA1C	1.1	1.2	2.6	-0.2	-1.2	-0.6	1.5	-0.9	-0.8	-1.2	-1.6
HDL Cholesterol	0.5	0.8	3.6	-0.1	0.4	1.9	-0.1	1.0	0.6	0.9	0.7
LDL Cholesterol	1.2	2.0	5.4	1.8	2.3	-0.6	-1.9	0.2	0.9	1.2	0.9
Lupus	1.1	1.6	5.8	-1.2	-1.1	-1.4	0.4	-0.8	-2.4	-0.9	-1.1
Neuroticism (2016)	1.1	1.6	3.5	-1.9	0.5	1.0	-0.0	-0.3	-1.5	-1.6	-1.8
Primary Biliary Cirrhosis	1.1	1.6	4.1	-0.4	-2.0	0.6	-0.1	-1.0	-1.8	-1.6	-1.2
Rheumatoid Arthritis	0.2	0.3	1.7	0.2	0.3	1.3	0.3	-0.1	0.8	-0.2	-0.0
Schizophrenia (2014)	0.8	1.7	6.5	-1.1	-2.5	0.6	1.0	-1.7	-1.3	0.0	-0.5
Triglycerides	1.1	1.9	6.8	1.7	1.5	-0.0	-2.6	0.1	0.8	1.2	0.8
Type 2 Diabetes (T2D) (2012)	1.6	1.9	8.1	0.8	-1.1	0.9	-2.8	-0.2	-0.2	1.8	1.0
Ulcerative Colitis	0.3	0.4	2.5	0.3	0.5	-0.1	-1.6	0.5	-0.6	-0.2	0.1
Blood Eosinophil Count	0.3	1.9	5.3	-1.5	-1.4	-0.7	-1.1	-1.7	-2.3	-0.8	-0.9
Blood Platelet Count	0.8	9.1	17.0	0.8	0.4	-3.6	-1.4	-4.1	-2.7	-4.1	-3.9
Blood Red Count	0.0	0.4	1.3	-0.8	-0.3	-1.1	0.2	0.2	-0.6	0.2	0.6
Blood White Count	0.6	4.4	12.2	1.5	1.3	-3.0	-3.5	-1.5	-2.7	-0.3	-0.7
Heel T-Score	0.7	5.4	16.2	-0.4	-1.0	-4.0	-1.8	-3.6	-2.5	-1.6	-0.9
BMI	0.1	0.7	1.9	-1.4	0.3	-0.5	0.1	1.2	-1.3	0.2	-0.1
Height	0.6	10.7	30.4	0.2	-1.8	1.3	3.6	1.5	5.5	3.6	4.7
Waist Hip Ratio (WHR)	1.5	6.8	20.5	1.7	-3.8	-3.8	-1.2	-4.5	-1.1	-0.1	0.3
Systolic Blood Pressure	1.2	5.8	15.4	2.0	-0.2	-0.3	-2.9	1.1	1.8	3.9	3.8
Smoking Status	0.7	1.6	6.9	-1.6	-2.6	-0.2	-0.5	-0.3	-1.6	-0.9	-0.2
Allergy or Eczema	0.8	2.1	5.9	1.5	0.4	2.4	-2.1	1.4	0.6	1.0	0.6
Cardiovascular Disease	0.3	1.0	4.1	-0.1	-2.0	-1.3	0.7	-0.2	-0.9	0.3	0.9
Hypothyroidism (self reported)	0.3	0.6	2.0	0.0	0.5	1.1	-1.4	1.1	-0.5	0.0	0.2
Respiratory disease	0.2	0.5	2.0	0.3	-0.8	-0.8	-0.6	-1.4	-0.2	0.1	0.3
Type 2 Diabetes (T2D) (2018)	1.0	1.9	5.4	-0.2	-1.6	-2.3	-0.4	-1.3	-2.0	-0.6	-0.8
Lung FEV1/FVC ratio	0.4	1.9	4.3	-0.3	1.1	1.2	-2.0	-0.1	-1.8	-0.8	-2.1
Lung FVC	0.8	4.2	18.5	-1.2	1.9	4.3	1.7	2.5	-0.2	-0.5	-1.1
Neuroticism	1.1	2.7	6.2	-2.5	-0.9	0.4	1.4	-1.2	-1.6	-2.0	-2.1
Chronotype (morning person)	0.3	0.6	1.8	0.8	0.5	-0.1	-1.4	-1.1	-0.4	-0.2	-0.9
Hair Pigment	0.1	1.5	3.3	-0.7	1.2	-1.3	0.3	-0.8	-1.0	-1.8	-1.8
Tanning	0.1	1.5	2.2	-1.5	-1.4	1.1	1.2	1.0	-1.2	-0.9	-1.4
Hand grip strength (left)	0.2	0.5	1.0	-0.7	0.0	0.8	0.7	-0.3	0.5	1.0	0.7
Number of treatments/medications taken	1.3	2.4	9.7	-1.2	-3.1	-1.5	1.0	-0.2	-1.7	-1.2	-0.1
Average weekly spirits intake	0.2	0.2	0.4	-0.2	0.5	-0.5	0.7	-0.0	0.6	-0.4	0.4
Sensitivity / hurt feelings	0.3	0.6	1.6	-1.1	-0.3	1.3	0.3	0.9	0.2	0.6	0.7
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.6	-0.6	0.1	0.2	-1.3	0.1	-1.2	-0.2	-0.8
Hearing difficulty/problems: Yes	1.1	1.7	6.2	-0.0	-2.5	-1.1	2.1	-0.1	0.2	-1.3	-0.6
Relative age of first facial hair	0.1	0.1	0.4	0.4	0.6	-0.4	0.4	-0.2	0.1	0.2	0.4
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	1.1	-0.4	-1.0	-0.8	-0.0	0.9	-0.2	0.3	0.2
Ever used hormone-replacement therapy (HRT)	1.3	1.6	4.0	-0.9	0.7	-2.0	0.0	-1.0	-1.0	-1.4	-2.0
Ever had hysterectomy (womb removed)	1.3	1.5	3.4	1.3	0.5	1.2	-0.5	1.8	1.5	0.9	1.5
Systolic blood pressure, automated reading	0.7	2.0	4.4	1.3	-0.6	0.1	-1.8	0.8	1.1	2.1	2.0
Eye problems/disorders: Diabetes related eye disease	3.2	3.5	11.6	0.3	-0.8	-3.2	0.2	-3.4	-1.0	-1.4	-1.6
Angina	0.7	0.9	2.6	0.1	-1.6	0.2	1.1	1.3	0.7	0.5	1.0
Medication for hormone replacement therapy	1.2	1.3	3.8	-1.3	-0.2	-0.3	0.7	-0.9	-1.0	-1.6	-1.9
Vitamin and mineral supplements	1.8	2.4	4.5	2.1	0.5	2.1	-1.2	1.3	0.9	2.1	1.4
Supplements: Zinc	0.2	0.2	0.6	-0.5	0.0	-0.7	0.0	0.4	0.4	0.4	0.3
Medication: Co-codamol	1.5	1.7	4.5	-1.0	-0.6	-0.7	-0.7	-1.2	-2.1	-1.5	-1.7
Medication: Metformin	0.5	0.7	1.3	0.5	-0.2	-1.1	-0.9	-1.0	-1.0	-0.9	-0.8
Diabetes (father)	1.1	1.3	4.1	1.4	-0.6	-0.4	-2.0	1.4	0.0	1.2	0.9
Diabetes (mother)	1.0	1.3	2.5	-1.0	1.6	-1.1	-0.1	-1.5	1.0	-0.9	-1.1
Severe depression (siblings)	0.6	0.7	1.2	-1.1	0.8	0.8	-0.8	1.0	-0.2	0.8	0.7
Pack years adult smoking proportion	0.5	0.8	2.4	0.1	-1.5	0.4	-1.1	0.7	-0.3	1.1	0.8
Impedance of leg (right)	0.7	3.2	7.7	2.8	-1.8	-1.6	-1.9	-2.1	1.1	1.1	1.3
Leg fat-free mass (left)	0.3	1.6	5.1	-2.3	1.0	1.0	1.4	1.7	0.4	0.7	0.2
Trunk fat percentage	0.3	1.3	3.5	0.6	0.7	-1.5	-0.8	-0.3	1.2	1.4	1.9
Hand grip strength (right)	0.5	1.4	3.3	-0.3	1.3	1.3	0.5	0.1	1.3	1.8	1.5
Townsend deprivation index at recruitment	0.6	0.8	4.9	-0.7	-0.2	-2.2	0.6	-0.6	-0.6	-0.4	-0.1
Current tobacco smoking	0.6	0.9	3.3	-0.5	-1.8	-0.3	-1.5	0.0	-1.1	-0.4	0.1
Average weekly fortified wine intake	0.5	0.6	1.2	0.6	-0.4	1.1	1.1	1.0	0.3	0.3	0.8
Maternal smoking around birth	0.7	1.0	2.3	0.6	-1.3	-1.4	-1.3	-0.3	-1.5	0.4	-0.1
Fed-up feelings	0.9	1.6	4.5	-2.1	-0.0	1.1	0.6	-0.8	-1.2	-1.2	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	2.4	-1.3	0.4	0.9	-1.6	-0.0	-1.3	-0.2	-1.1
Relative age voice broke	0.1	0.1	0.6	0.2	-0.3	0.2	0.8	0.1	0.2	-0.4	0.1
Taking other prescription medications	1.0	1.6	3.8	-1.0	-1.9	-1.9	0.3	-1.1	-1.5	-0.8	-0.6
Age when periods started (menarche)	0.3	0.6	1.8	0.2	-0.5	-0.7	-0.2	-0.8	-1.0	-0.9	-1.3
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.1	-0.5	-0.6	0.1	-1.0	0.7	-1.0	-0.0	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.2	0.3	0.5	-0.1	0.1	0.2	0.2	0.0	0.2
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	2.2	0.2	-0.0	-1.5	-0.8	-1.0	-1.1	-1.0	-0.6
Qualifications: CSEs or equivalent	0.4	0.5	2.0	-0.2	-0.2	0.3	-1.0	0.8	0.1	1.4	0.4
Serious illness, injury or assault to yourself	1.0	1.2	3.6	-1.3	0.1	1.6	-0.7	0.3	-1.9	-0.6	-1.0
High blood pressure	0.3	0.7	2.3	1.1	-1.5	-0.5	0.3	0.7	0.5	0.4	1.1
Hayfever, allergic rhinitis or eczema	0.6	1.4	4.2	1.3	0.1	2.1	-1.0	1.6	0.5	0.8	0.7
Multivitamins +/- minerals	0.6	0.8	2.7	-1.6	-0.4	-0.6	1.1	-0.3	-0.5	-1.1	-0.6
Stomach or abdominal pain in last month	0.8	1.0	4.7	-1.2	-1.0	0.1	-0.8	0.6	-2.2	-0.3	-0.3
Supplements: Glucosamine	0.2	0.2	0.9	-0.4	0.3	-0.1	-0.2	0.3	0.4	-0.5	-0.9
Diverticular disease/diverticulitis (self-reported)	2.5	2.9	7.9	-2.3	-2.2	-0.2	-0.6	-1.2	-2.8	-1.3	-1.4
Medication: Atenolol	1.0	1.3	2.9	1.2	0.8	0.3	-0.8	1.3	0.2	1.7	1.6
Medication: Levothyroxine sodium	1.0	1.7	5.2	-0.9	-0.8	-1.6	0.2	-0.5	-2.3	-1.7	-1.1
Sitting height	1.3	9.1	20.8	1.2	2.0	2.3	-1.0	2.3	4.5	4.6	3.9
Chronic bronchitis/emphysema (father)	1.1	1.3	4.3	-0.9	0.1	-0.5	2.1	-1.2	0.6	-1.5	-0.9
High blood pressure (mother)	0.6	0.8	2.4	1.6	-0.8	0.0	0.0	0.8	1.0	0.9	1.1
Body mass index (BMI)	0.3	1.1	2.5	-1.6	1.3	-0.8	-0.2	0.4	-1.5	-0.7	-1.1
Impedance of leg (left)	0.7	3.6	8.6	2.9	-1.5	-1.7	-2.3	-2.2	1.2	1.1	1.4
Leg predicted mass (left)	0.3	1.5	5.1	-2.3	1.0	0.9	1.4	1.7	0.3	0.6	0.1
Trunk fat mass	0.2	0.9	2.1	-0.2	0.7	-1.2	-0.3	-0.0	1.1	1.3	1.4
Waist circumference	0.1	0.5	2.6	-0.6	0.4	-1.6	-0.2	-0.5	-0.6	-0.3	-0.3
Number of incorrect matches in round	0.4	0.6	1.8	-0.4	0.2	-0.5	-0.3	-0.3	-1.4	-0.9	-1.3
Past tobacco smoking	0.2	0.4	1.5	1.2	1.1	-0.1	-0.3	0.4	-0.2	0.3	-0.4
Alcohol usually taken with meals	0.4	0.6	2.2	-0.1	0.0	-1.2	0.1	0.8	-1.5	-0.3	0.0
Nervous feelings	0.3	0.6	1.9	-1.0	-0.1	-0.4	1.0	-1.4	-0.4	-0.4	-0.4
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.3	10.0	-1.5	0.5	-0.7	-0.6	-1.9	-2.6	-1.7	-3.2
Hearing difficulty/problems with background noise	0.6	0.9	3.6	-0.3	-1.9	-0.2	1.8	-0.0	-0.1	-0.4	0.1
Hair/balding pattern: Pattern 2	0.4	0.5	1.5	-0.1	1.1	-0.1	-1.2	-0.6	0.1	0.5	0.6
Had menopause	0.4	0.5	1.1	-1.0	-0.5	-0.3	0.7	0.8	-0.3	-0.9	-0.4
Had other major operations	0.5	0.6	1.8	-0.8	-0.9	-0.0	-0.1	-0.0	-1.3	-0.9	-0.5
Forced vital capacity (FVC)	0.9	3.4	12.4	-0.3	1.2	3.5	1.9	2.0	2.1	1.0	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.9	0.3	0.5	-0.6	-0.9	-0.3	-0.2	0.4	0.0
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.7	-0.5	1.2	-0.0	0.6	-0.4	0.2	-1.3	-0.5
Qualifications: None of the above	0.8	1.8	4.8	-1.7	-2.2	-0.7	0.2	-0.8	-1.8	-1.1	-1.0
Financial difficulties in last 2 years	0.9	1.2	2.4	-1.0	-1.0	0.3	0.6	-1.0	-1.1	-1.6	-1.5
Mouth/teeth dental problems	0.5	0.8	4.0	2.0	0.8	-1.1	-0.4	-0.3	0.6	-0.1	0.1
Heart attack	0.4	0.5	3.4	-0.5	-1.9	-0.0	0.4	0.3	0.2	-0.0	0.0
Allergy	0.3	0.6	2.8	-1.7	0.6	-0.5	0.5	-0.1	-1.0	-0.3	-0.5
Pain all over the body in last month	0.2	0.2	0.6	0.3	0.8	-0.8	-0.0	0.6	0.0	-0.1	-0.2
Diabetes (self-reported)	0.6	1.0	2.7	0.1	-1.2	-1.7	-0.4	-0.9	-1.6	-0.5	-0.1
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	3.3	0.6	1.8	-0.1	0.6	0.3	0.9	-0.9	0.0
Medication: Ramipril	1.7	2.1	4.9	-1.6	-0.6	-2.2	-0.3	-1.9	-1.6	-1.0	-1.3
Medication: Simvastatin	0.7	1.1	3.2	0.7	-1.6	-0.2	0.8	0.4	0.2	1.1	1.8
Fluid intelligence score	1.3	2.7	6.2	1.8	0.5	1.3	-0.3	2.0	2.5	1.3	2.0
Illnesses of siblings	0.2	0.3	0.7	0.0	0.8	0.6	0.1	0.7	-0.8	0.3	0.1
Neuroticism score	2.6	5.3	13.9	-3.7	-1.3	-0.0	1.9	-1.7	-2.5	-2.6	-2.8
Weight	0.1	0.7	2.7	-1.6	0.9	-0.3	0.3	0.9	0.3	0.7	0.5
Impedance of arm (right)	1.3	6.0	20.7	2.6	-2.0	-0.4	0.1	-0.8	3.1	2.4	4.5
Arm fat percentage (right)	0.1	0.5	1.5	0.1	0.8	-1.1	-0.3	-0.0	0.6	0.6	1.2
Trunk fat-free mass	0.3	1.6	7.0	-2.6	1.1	0.7	1.3	1.1	0.1	0.2	-0.9
Hip circumference	0.2	1.1	4.8	-1.5	2.2	0.1	-0.1	1.0	-0.5	-0.0	-0.6
Time employed in main current job	1.1	1.3	6.4	-0.4	-0.3	-2.5	0.6	-1.3	-1.1	-0.6	0.2
Alcohol intake versus 10 years previously	0.1	0.2	0.5	-0.7	0.1	-0.2	-0.4	-0.7	-0.3	-0.1	-0.1
Father’s age at death	0.4	0.6	1.9	-0.2	0.4	-0.4	0.1	-0.7	-0.6	-1.2	-1.4
Worrier / anxious feelings	0.3	0.6	1.1	-1.0	-0.8	0.9	0.9	-0.4	-0.0	-1.0	-0.5
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.5	5.8	-2.4	-0.3	-0.3	-0.6	-0.7	-2.4	-1.5	-2.2
Falls in the last year	1.9	2.5	5.8	-1.8	-1.9	-0.1	0.6	-1.3	-1.8	-1.5	-2.4
Hair/balding pattern: Pattern 3	0.3	0.4	1.5	-0.6	-1.0	1.2	0.7	-0.2	-0.0	-0.2	-0.1
Number of live births	0.5	0.7	2.3	-0.3	-0.6	1.5	1.1	0.7	1.1	0.1	0.2
Forced expiratory volume in 1-second (FEV1)	1.2	4.0	16.6	0.2	1.6	4.1	0.8	2.7	1.8	1.2	0.7
Pulse rate	0.9	1.5	4.6	1.2	2.1	0.2	-1.4	0.6	1.5	0.6	0.9
Happiness	0.4	0.5	1.5	0.1	0.4	0.8	-1.2	0.7	-0.9	0.3	-0.1
Noisy workplace	2.7	3.3	8.3	-1.1	-1.7	-1.6	0.1	-1.5	-2.9	-1.5	-2.6
Qualifications: A levels/AS levels or equivalent	0.7	1.5	4.3	0.8	-0.3	0.3	-1.1	1.3	0.4	2.1	1.9
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	3.8	1.3	2.0	-0.9	-0.5	0.3	1.4	0.4	0.2
Mouth/teeth dental problems: Dentures	0.8	1.4	6.9	-0.1	-2.6	-0.2	1.2	0.6	-0.1	0.8	1.2
Asthma	0.9	1.7	6.2	0.2	-1.4	-2.0	0.4	-2.5	-0.7	-0.7	-0.4
Medication: Ibuprofen (e.g. Nurofen)	2.8	3.6	9.6	-1.3	-0.9	-0.2	0.5	-1.6	-3.1	-2.4	-2.8
Medication: Cholesterol lowering	1.2	1.9	7.5	0.4	-2.7	-1.2	0.3	-1.8	-1.7	0.1	-0.0
Depression (self-reported)	1.0	1.2	3.3	-0.8	-0.3	0.8	-1.8	0.8	-1.3	1.3	0.9
Medication: Lansoprazole	1.8	2.0	5.3	-0.3	0.7	-1.5	1.6	-1.0	-0.9	-2.3	-2.0
Prospective memory result	0.2	0.3	0.8	-0.5	0.9	0.8	0.0	0.6	-0.0	0.1	-0.3
Lung cancer (father)	0.9	1.0	5.9	-0.2	-0.6	0.4	2.4	0.7	1.0	-0.7	-0.3
Illnesses of mother	0.5	0.6	2.9	-0.4	-0.1	0.3	-0.9	0.1	-1.7	-0.2	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.6	16.4	-0.6	1.3	4.1	1.4	2.6	1.0	0.7	0.2
Pulse wave Arterial Stiffness index	1.6	1.8	3.7	-1.1	1.0	-1.9	1.6	-1.3	0.4	-1.6	-1.3
Impedance of arm (left)	1.3	5.9	18.9	2.8	-1.8	-0.3	-0.1	-0.9	3.3	2.4	4.3
Arm fat mass (right)	0.1	0.4	1.0	-0.7	1.0	-0.6	-0.1	0.5	0.3	0.5	0.7
Trunk predicted mass	0.3	1.5	7.1	-2.7	0.9	0.7	1.3	1.0	0.1	0.2	-0.9
Standing height	0.6	5.7	16.1	-0.2	-0.6	1.3	1.3	1.4	4.0	3.3	3.6
Length of working week for main job	1.2	1.3	3.0	-0.8	-1.3	-1.7	0.9	-1.1	-1.4	-0.8	-0.3
Exposure to tobacco smoke at home	0.6	0.7	1.6	-1.0	-1.1	1.2	-1.0	0.0	0.8	0.3	-0.4
Breastfed as a baby	0.2	0.3	0.8	0.0	0.9	-0.9	-0.1	0.5	0.2	0.1	0.6
Tense / ‘highly strung’	1.2	2.1	6.0	-2.4	-1.8	1.4	0.2	-0.5	-1.5	-0.8	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.5	0.5	0.6	-0.2	-0.2	-0.2	0.3	0.7	0.1
Hair/balding pattern: Pattern 4	0.6	1.6	8.0	-0.6	-1.8	-0.1	2.8	0.7	0.6	-0.3	0.1
Birth weight of first child	0.7	1.4	2.9	1.3	0.7	1.7	-0.3	1.5	1.2	0.9	1.1
Peak expiratory flow (PEF)	0.6	1.4	5.4	0.5	0.8	2.3	-0.8	1.5	0.2	1.3	0.7
Pulse wave reflection index	3.3	4.1	8.0	-2.8	-1.8	-1.8	1.5	-1.8	-1.6	-2.3	-2.1
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.0	0.3	-0.4	0.1	0.1	1.0	0.6	0.4	0.3
Loud music exposure frequency	2.6	2.8	4.7	-2.0	-1.4	0.9	1.9	-1.0	-1.9	-2.2	-1.6
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	4.7	0.4	0.2	1.6	0.1	2.2	0.5	1.2	1.2
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.6	-1.9	-1.0	0.5	-0.8	-0.3	-1.2	-0.4	-0.7
Blood clot in the leg (DVT)	0.5	0.6	1.3	0.7	-0.6	-0.3	-1.1	1.1	0.7	0.9	0.5
Medication: Paracetamol	1.2	2.0	6.2	-1.3	-1.3	-0.3	-0.3	-0.8	-2.5	-1.4	-1.9
Headache pain in last month	1.0	1.7	6.1	-0.4	1.2	-1.0	-2.5	-1.2	-1.4	0.4	-1.0
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	7.5	0.1	2.7	1.1	-0.7	1.6	2.3	0.5	0.6
Glaucoma (self-reported)	1.5	1.8	8.1	1.2	0.2	-2.8	-1.2	-1.7	-0.4	0.3	0.4
Gout (self-reported)	0.7	0.9	2.8	-1.5	-0.6	1.7	0.6	0.3	-0.3	-1.1	-0.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.1	0.0	0.6	-0.6	-1.0	-0.0	-1.0	-0.5	-0.3
Medication: Amlodipine	0.2	0.3	0.7	0.9	-0.4	-0.3	0.4	0.4	0.3	0.2	0.8
Medication: Ventolin 100micrograms inhaler	0.5	0.7	1.8	1.1	-0.2	0.9	0.2	-1.3	1.1	0.1	0.6
Birth weight	0.3	0.7	1.2	0.9	-0.1	-1.1	0.8	0.9	1.0	0.2	1.1
Chronic bronchitis/emphysema (mother)	0.4	0.4	0.8	-0.3	-0.0	0.4	0.3	0.9	0.9	0.9	0.8
High blood pressure (siblings)	0.2	0.3	0.8	0.3	-0.1	0.3	-0.8	0.6	0.9	0.3	0.4
Forced vital capacity (FVC), Best measure	1.0	3.8	14.8	-0.6	1.1	3.8	2.3	2.2	1.6	0.8	0.4
Body fat percentage	0.2	0.9	3.1	0.4	0.6	-1.8	-1.0	-0.6	0.5	1.0	1.1
Leg fat percentage (right)	0.3	1.2	4.3	0.0	-0.1	-2.1	-1.5	-1.0	-1.2	-0.3	-0.8
Arm fat-free mass (right)	0.2	1.3	5.1	-2.3	1.5	0.3	0.6	1.0	-0.2	0.1	-1.2
Exposure to tobacco smoke outside home	0.8	1.0	3.7	-0.6	0.5	1.9	0.3	1.6	1.1	0.2	-0.3
Comparative body size at age 10	0.2	0.5	1.7	-0.7	1.3	0.5	0.9	0.0	0.6	-0.5	-0.5
Number of full brothers	0.5	0.6	2.1	-1.0	-1.5	-0.5	0.7	-0.5	-0.6	0.2	0.7
Worry too long after embarrassment	1.3	2.2	5.2	-2.3	-0.5	0.8	1.6	-1.2	-1.0	-1.6	-2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.9	-1.0	-0.3	-0.1	0.0	0.2	-0.3	0.4	0.5
Wheeze or whistling in the chest in last year	1.2	2.1	8.2	-1.4	-2.9	-0.9	-1.1	-1.7	-1.3	-0.0	-0.0
Number of children fathered	0.6	0.7	1.7	-1.2	-1.3	-0.7	0.2	-0.1	-1.2	0.1	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.4	0.0	-0.4	0.3	1.2	0.5	0.2	0.4	0.9
Age at first live birth	0.4	0.7	1.7	-0.7	0.1	-0.4	1.3	-1.3	-0.4	-0.8	-0.7
Pulse wave peak to peak time	2.1	2.5	5.1	1.2	-1.0	2.3	-1.5	1.6	0.1	2.1	1.8
Health satisfaction	0.3	0.5	1.4	0.2	1.2	0.8	-0.8	0.6	0.1	-0.5	-0.5
Shortness of breath walking on level ground	1.1	1.3	2.9	1.3	0.7	0.6	-1.0	0.4	1.7	1.5	1.2
Qualifications: College or University degree	0.1	0.3	1.1	0.7	0.7	-0.0	0.1	0.4	1.1	0.1	0.5
Eye problems/disorders: None of the above	1.2	1.4	3.2	-1.6	-0.0	1.8	0.8	0.0	-0.6	-1.5	-1.4
Mouth/teeth dental problems: Loose teeth	2.7	3.2	5.4	1.6	1.0	1.6	-0.8	2.1	2.3	2.0	2.3
Emphysema/chronic bronchitis	0.6	0.7	2.5	0.4	-0.8	-0.1	0.0	-0.1	1.2	0.9	1.6
Medication for pain relief, constipation, heartburn	2.9	4.9	11.1	2.3	2.4	1.5	-0.9	1.3	3.3	2.5	2.5
Neck or shoulder pain in last month	0.5	0.7	2.2	-0.3	1.2	-1.5	-1.1	-0.7	0.2	0.4	0.1
Medication: Blood pressure	0.3	0.5	1.5	0.6	-1.2	-0.6	0.0	-0.4	-1.1	0.2	0.2
Angina (self-reported)	0.7	0.9	2.9	0.0	-1.7	-0.0	1.3	1.1	0.6	0.3	0.8
Migraine (self-reported)	0.6	0.8	2.4	-0.6	0.4	-0.4	-0.9	-1.5	-1.0	-0.4	-1.1
Medication: Ibuprofen	1.5	1.8	4.5	-0.7	-0.7	-0.1	1.1	-1.0	-1.9	-2.1	-1.8
Medication: Allopurinol	0.3	0.3	0.6	-0.7	0.4	0.8	-0.6	0.1	-0.6	-0.8	-0.4
Medication: Omeprazole	2.8	3.4	6.4	-2.0	-2.5	-1.9	2.0	-1.0	-1.5	-2.0	-1.3
Medication: Seretide 50 evohaler	0.6	0.7	1.3	-1.0	-0.6	-1.0	0.6	-1.0	-1.1	-0.7	-0.3
Mean time to correctly identify matches	0.3	0.5	2.3	0.1	0.1	1.5	-0.6	0.7	0.4	0.5	0.7
Heart disease (mother)	0.5	0.6	2.9	0.3	-0.6	-0.2	1.2	-0.1	1.7	0.1	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	3.0	0.4	1.4	1.3	-0.5	-0.3	1.7	1.4	1.3
Whole body fat mass	0.2	0.7	1.3	-0.2	0.9	-1.0	-0.5	0.2	0.7	1.1	1.1
Leg fat mass (right)	0.1	0.3	1.3	-0.4	0.5	-1.1	-0.8	-0.0	-0.5	0.1	-0.4
Arm predicted mass (right)	0.2	1.3	5.3	-2.3	1.3	0.1	0.5	0.8	-0.4	0.0	-1.4
Pulse rate, automated reading	0.2	0.5	3.0	0.2	1.7	0.2	-0.8	0.0	-0.2	-0.4	-0.4
Alcohol intake frequency.	0.9	2.1	11.2	-1.2	-0.5	-1.0	-0.5	-1.3	-3.3	-0.1	-1.1
Comparative height size at age 10	0.7	4.0	10.1	0.0	-0.2	0.7	0.4	1.6	3.0	3.2	3.2
Number of full sisters	0.6	0.7	3.5	-1.0	-0.6	-1.9	0.4	-0.3	0.4	0.4	0.6
Suffer from ‘nerves’	0.2	0.3	1.1	-1.0	0.8	-0.4	0.3	-0.4	-0.2	-0.3	-0.6
Overall health rating	0.2	0.4	1.1	-0.7	0.3	0.1	-1.0	0.3	-1.1	-0.0	-0.4
Chest pain or discomfort	0.3	0.5	1.7	0.1	-1.3	0.9	0.0	0.1	0.4	0.7	0.7
Had major operations	0.2	0.2	1.0	0.2	-1.0	-0.2	-0.3	0.6	-0.4	-0.1	-0.0
Age at last live birth	0.3	0.5	1.1	-1.0	-0.5	0.2	0.8	-0.7	-0.7	-0.5	-0.7
Family relationship satisfaction	0.4	0.5	2.6	0.5	1.6	-0.2	-0.9	0.2	-0.2	-0.2	-0.8
Leg pain on walking	0.3	0.4	1.7	0.4	-1.3	-0.6	0.4	0.7	0.1	0.0	0.0
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.6	-0.3	-0.3	0.8	-0.2	0.1	-0.1	-0.4	-0.6
Commuting to job workplace: Car/motor vehicle	2.0	2.3	7.0	-2.6	0.3	-1.4	0.2	-1.2	-1.9	-1.3	-1.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.0	0.1	0.4	-0.2	-0.6	0.1	0.7	1.0	1.0
Medication: Aspirin	0.5	0.7	1.8	0.1	-1.3	-0.2	-0.4	1.1	-1.2	0.3	0.8
Supplements: Vitamin C	0.3	0.4	0.8	0.1	-0.8	-0.5	0.1	0.9	0.7	0.3	0.8
Knee pain experienced in last month	0.5	0.8	2.0	-1.2	-0.7	0.0	-0.5	-0.5	-1.2	-0.8	-1.4
Hypertension (Self-reported)	0.3	0.8	2.4	0.9	-1.5	-0.9	0.3	0.3	0.3	0.5	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	2.3	-1.2	0.5	-0.9	0.1	0.1	-1.5	-1.1	-1.4
Illnesses of father: Heart disease	4.0	5.5	13.1	1.7	0.4	1.9	-2.5	2.2	1.9	3.6	3.1
Illnesses of siblings: Diabetes	4.9	6.1	10.2	-2.6	-1.5	-2.0	1.8	-3.1	-1.8	-3.0	-3.2
Smoking status: Previous	0.3	0.4	1.1	-1.1	-0.6	0.0	1.0	-0.2	0.4	-0.0	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.9	-0.4	0.6	1.4	-0.3	0.7	0.3	0.8	0.4
Whole body fat-free mass	0.3	1.6	7.2	-2.7	1.1	0.8	1.3	1.3	0.1	0.3	-0.6
Leg fat-free mass (right)	0.3	1.6	5.0	-2.2	1.2	1.1	1.4	1.6	0.5	0.6	0.2
Arm fat percentage (left)	0.1	0.4	1.6	0.1	0.6	-1.2	-0.3	-0.3	0.3	0.5	1.0
Average weekly red wine intake	0.9	1.3	3.4	0.6	0.8	1.1	-0.4	1.4	1.8	0.9	1.4
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.7	0.4	-1.6	-0.3	0.9	0.5	-1.0	-0.0	0.3
Mood swings	1.7	3.1	6.2	-2.3	-2.5	-0.1	1.2	-1.1	-2.0	-1.8	-1.9
Loneliness, isolation	0.6	0.8	1.8	-1.2	-0.9	1.4	0.3	0.5	-0.8	-0.5	-1.0
Long-standing illness, disability or infirmity	0.6	0.9	3.7	-0.1	-1.9	-0.9	-0.9	0.4	-1.1	0.3	0.3
Ever had bowel cancer screening	0.8	0.9	1.9	-1.2	-1.4	-1.3	0.7	-0.2	-0.9	-0.8	-0.7
Diabetes diagnosed by doctor	0.8	1.4	4.2	-0.1	-0.8	-2.1	-0.6	-1.4	-1.6	-0.8	-0.8
Ever had stillbirth, spontaneous miscarriage or termination	2.2	2.4	5.8	-0.7	-1.8	-1.0	-0.8	-2.4	-1.6	-1.3	-2.0
Friendships satisfaction	1.9	2.4	4.5	0.6	1.9	2.0	-0.9	2.1	1.4	1.5	1.1
Qualifications: nursing, teaching	1.0	1.5	2.3	1.3	1.5	1.2	-1.0	1.1	1.1	1.5	1.0
Commuting to job workplace: Walk	1.1	1.2	4.0	2.0	-1.8	0.2	-0.1	-1.0	0.9	0.2	0.5
Eye problems/disorders: Cataract	0.7	0.8	2.2	0.4	0.0	0.2	0.6	1.4	0.6	1.1	1.5
Mouth/teeth dental problems: Mouth ulcers	1.8	2.8	6.6	-2.2	1.6	0.9	1.0	-1.8	-0.8	-1.5	-2.6
Medication for cholesterol	0.8	1.2	5.3	1.1	0.1	2.3	-0.5	0.8	0.2	1.3	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.8	0.9	0.2	1.0	-0.3	1.7	1.5	1.5	1.1
Back pain experienced in last month	0.7	0.9	2.8	-1.7	0.3	0.2	-0.5	-0.4	-1.5	-0.4	-1.4
Mineral and other dietary supplements	0.8	1.1	2.7	0.7	0.2	1.5	0.6	1.0	0.3	1.3	1.6
Breast cancer (self-reported)	0.4	0.4	1.0	-0.8	-0.7	-0.7	0.0	0.7	-1.0	-0.1	0.2
Asthma (self-reported)	0.7	1.4	5.2	-0.0	-1.4	-1.8	0.6	-2.3	-0.4	-0.6	-0.2
Osteoporosis (self-reported)	0.4	0.6	2.0	1.0	0.3	-0.7	-1.4	-0.4	-0.2	0.8	0.3
Osteoarthritis (self-reported)	1.5	2.0	4.9	-2.2	-0.8	-0.3	0.7	-0.4	-1.5	-2.2	-1.6
Medication: Aspirin	0.5	0.7	2.0	0.2	-1.2	-0.3	-0.4	1.1	-1.4	0.3	0.8
Medication: Gliclazide	0.6	0.6	1.6	0.9	1.3	-1.2	-0.9	0.4	-0.4	0.2	0.3
Illnesses of father: None of the above (group 1)	2.5	3.1	5.8	-0.1	-0.8	-1.8	1.4	-1.8	-2.1	-2.3	-2.4
Smoking status: Current	0.8	1.3	4.1	-0.7	-2.0	-0.8	-1.4	-0.6	-1.3	-1.0	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.2	11.8	-0.1	1.1	3.4	0.9	1.5	-0.3	-0.4	-1.1
Whole body water mass	0.3	1.5	6.7	-2.6	1.2	0.7	1.2	1.3	0.1	0.3	-0.6
Leg predicted mass (right)	0.3	1.6	4.9	-2.2	1.2	1.1	1.4	1.6	0.5	0.6	0.2
Arm fat mass (left)	0.1	0.4	1.0	-0.7	1.0	-0.7	-0.0	0.5	0.3	0.6	0.6
Number of self-reported non-cancer illnesses	0.4	0.7	3.5	-0.6	-1.9	-0.2	0.2	0.6	-0.6	0.2	0.9
Average weekly champagne plus white wine intake	2.5	3.4	6.3	1.4	1.5	2.1	-0.9	1.6	2.4	2.5	1.9
Miserableness	1.9	3.3	6.7	-2.5	-0.0	-0.3	0.6	-1.6	-2.5	-1.9	-2.6
Guilty feelings	1.4	2.1	5.7	-2.4	-0.2	1.1	1.4	0.1	-1.5	-1.6	-1.6
Wears glasses or contact lenses	0.1	0.1	0.4	-0.5	-0.3	0.2	0.0	0.6	-0.1	0.3	0.0
Ever taken oral contraceptive pill	0.6	0.7	3.0	0.9	-0.0	-1.7	0.5	-1.0	0.2	-0.2	0.1
Hearing aid user	0.4	0.5	1.2	0.3	-1.1	0.5	-0.8	0.5	-0.7	0.9	-0.2
Mother’s age at death	1.6	2.0	7.5	-1.7	-1.3	-0.9	0.3	-0.1	-2.7	-0.9	-1.5
Financial situation satisfaction	6.3	7.8	16.4	-2.3	-0.1	-2.3	0.6	-4.0	-2.8	-3.3	-4.0
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.8	0.7	-0.5	0.5	-0.9	-0.1	0.6	0.9	0.3
Commuting to job workplace: Public transport	1.3	1.5	4.8	2.2	-0.4	1.1	-0.9	1.6	0.8	1.1	0.9
Eye problems/disorders: Glaucoma	1.2	1.4	3.6	1.9	-0.1	-1.5	-1.5	-1.6	0.2	0.7	0.4
Medication: Blood pressure	0.3	0.6	2.2	-0.3	-0.3	-1.5	0.7	0.6	1.1	-0.1	0.8
Pain type(s) experienced in last month: Hip pain	4.1	5.2	15.1	-2.0	-0.7	-0.2	1.8	-2.7	-1.6	-2.9	-3.9
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.5	0.2	0.3	-0.8	-1.2	0.2	0.9	0.4	-0.1
High cholesterol (Self-reported)	0.2	0.4	1.3	0.7	-0.1	-1.2	0.0	0.1	-0.8	0.2	0.8
Medication: Bendroflumethiazide	0.6	0.9	3.7	0.5	0.5	-0.5	-0.9	0.6	1.9	1.1	0.8
Medication: Paracetamol	1.3	2.0	7.1	-1.4	-0.8	-0.2	0.3	-0.9	-2.7	-1.6	-1.7
Medication: Lisinopril	1.2	1.5	4.5	1.1	-1.2	-2.1	1.3	-1.1	-0.0	-1.3	-0.6
Medication: Atorvastatin	0.7	0.9	2.6	-0.7	-1.6	-1.1	-0.4	-0.2	-1.6	0.2	0.0
Illnesses of father: High blood pressure	0.6	0.8	2.7	-1.6	0.1	0.4	-0.2	-0.6	-0.9	-0.9	-1.1
Alcohol drinker status: Never	0.5	0.6	1.6	-0.4	-0.6	-1.2	1.0	-0.5	-1.1	-0.3	-0.3
Ever smoked	0.2	0.3	1.0	-0.6	-1.0	0.8	-0.4	0.4	0.1	0.0	0.7
Basal metabolic rate	0.2	1.3	5.3	-2.3	1.2	0.6	1.0	1.3	0.3	0.6	-0.3
Leg fat percentage (left)	0.3	1.2	4.2	0.1	0.1	-2.0	-1.7	-0.8	-1.1	-0.2	-0.6
Arm fat-free mass (left)	0.2	1.2	5.4	-2.3	1.2	0.6	0.3	1.2	-0.3	0.4	-0.8
Number of operations (self-reported)	1.2	1.9	4.3	-1.5	-2.1	0.1	-0.5	0.1	-1.8	-1.3	-1.7
Average weekly beer plus cider intake	0.4	0.5	1.1	-0.7	0.1	-0.5	0.7	-0.9	-0.8	-1.0	-0.6
Irritability	0.6	1.0	2.8	-1.7	-0.1	1.2	-0.5	-0.0	-0.8	-0.7	-1.4
Risk taking	0.4	0.5	1.2	-0.9	-0.3	1.1	-1.0	0.3	-0.7	0.7	0.1
Ever had prostate specific antigen (PSA) test	0.6	0.7	5.0	0.2	-2.2	-0.5	-0.5	0.2	0.3	-0.0	0.4
Fractured/broken bones in last 5 years	0.4	0.5	2.5	0.8	1.6	-0.5	-0.3	-0.1	-0.3	-0.5	-0.4
Age started oral contraceptive pill	0.5	0.6	1.6	1.3	0.2	-0.6	0.2	0.6	1.1	0.6	0.7
Diastolic blood pressure, automated reading	0.7	2.2	4.1	1.2	0.4	1.7	-1.4	2.0	0.8	1.8	1.9
Ever depressed for a whole week	0.7	0.9	2.9	1.1	1.7	0.4	-1.5	0.3	0.6	-0.5	-0.4
Unable to work because of sickness or disability	0.2	0.3	0.6	-0.0	0.7	-0.7	-0.5	-0.3	-0.8	0.3	0.2
Commuting to job workplace: Cycle	0.6	0.7	1.9	0.6	-1.4	0.8	-0.4	0.0	0.1	1.1	1.0
Myopia	0.8	1.1	6.1	-0.6	2.5	0.1	-0.2	0.4	0.3	-0.6	-1.3
Vascular/heart problems diagnosed by doctor	0.5	1.3	4.0	-1.2	2.0	0.5	-0.1	-1.2	-0.5	-0.9	-1.6
Cholesterol lowering medication	0.8	1.2	3.5	0.8	0.5	-1.4	-0.2	1.1	0.9	0.9	1.9
Medication: Omeprazole (e.g. Zanprol)	2.8	3.4	5.4	-2.1	-2.0	-2.3	2.2	-0.9	-1.3	-2.1	-1.1
Pain experienced in last month	1.1	1.8	3.9	0.9	0.5	1.5	0.7	1.5	2.0	0.8	1.9
Supplements: Calcium	1.0	1.1	3.5	-0.0	-1.0	-0.5	-1.9	-0.2	-1.6	-0.3	-1.0
Basal cell carcinoma (self-reported)	2.2	2.6	5.9	0.3	0.7	-2.4	-1.0	-2.2	-1.6	-1.3	-2.1
Heart attack/myocardial infarction (self-reported)	0.4	0.5	3.4	-0.5	-1.8	0.1	0.4	0.4	0.1	0.0	0.1
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.0	0.7	-0.6	-0.4	-0.9	1.0	0.5	0.8	0.4
Heart disease (siblings)	0.6	0.7	2.5	-0.4	-1.6	-0.2	1.2	-0.8	0.1	-0.9	-0.3
Alcohol drinker status: Previous	0.6	0.6	1.6	-0.8	-0.2	1.1	0.1	-1.0	-0.8	-0.2	-1.3
Pack years of smoking	0.6	0.9	3.2	0.2	-1.8	-0.0	-1.1	0.5	-0.3	1.2	0.8
Impedance of whole body	1.0	5.1	12.9	3.0	-1.9	-0.9	-1.1	-1.4	2.6	2.2	3.6
Leg fat mass (left)	0.1	0.4	1.1	-0.3	0.7	-1.1	-1.0	0.1	-0.4	0.4	-0.1
Arm predicted mass (left)	0.2	1.2	4.4	-2.1	1.3	0.8	0.3	1.4	0.2	0.6	-0.5