TWAS hub - IFNG

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0534	0.0120	3.3e-10	0.064	0.035	0.058	0.057	0.059	9.5e-20	1.7e-11	3.7e-18	8e-18	1.7e-18
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0239	0.0147	9.3e-03	0.010	0.007	-0.002	NA	0.003	2.2e-02	4.6e-02	5.9e-01	NA	1.4e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Heart disease (siblings)	6.0	7.3	14.4	-0.5	3.8
Hair/balding pattern: Pattern 3	5.4	8.0	15.6	-3.9	0.7
Medication: Ventolin 100micrograms inhaler	4.7	6.1	6.5	2.5	2.4
Respiratory disease	4.5	10.0	11.2	3.4	3.0
Asthma (self-reported)	4.5	9.0	13.8	2.0	3.7
Illnesses of siblings	4.1	5.8	11.6	0.0	-3.4
Asthma	4.0	7.9	12.4	1.8	3.5
Reason for reducing amount of alcohol drunk: Health precaution	4.0	4.7	9.0	3.0	0.6
Hypothyroidism (self reported)	3.8	8.7	9.2	3.0	-2.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.4	7.1	11.0	-1.8	-3.3
Bilateral oophorectomy (both ovaries removed)	3.2	3.7	4.3	-1.7	2.1
Medication: Levothyroxine sodium	3.2	5.4	6.3	2.1	-2.5
Illnesses of siblings: Diabetes	3.2	4.0	4.8	1.8	2.2
Medication: Atenolol	3.1	3.9	6.3	1.2	-2.5
Shortness of breath walking on level ground	3.0	3.6	6.2	1.0	2.5
Ever had hysterectomy (womb removed)	2.9	3.2	6.3	-2.5	0.4
Long-standing illness, disability or infirmity	2.9	4.5	8.9	3.0	0.3
Smoking Status	2.8	6.7	13.2	0.3	3.6
Chronic bronchitis/emphysema (father)	2.8	3.3	6.2	2.5	0.6
Hypothyroidism/myxoedema (self-reported)	2.8	5.5	7.3	1.9	-2.7
Emphysema/chronic bronchitis	2.8	3.2	6.4	0.1	2.5
Qualifications: nursing, teaching	2.6	4.1	7.0	-1.1	-2.6
Eye problems/disorders: Glaucoma	2.5	2.9	3.3	-1.6	-1.8
Ever depressed for a whole week	2.5	3.0	5.8	2.4	-0.5
Unable to work because of sickness or disability	2.5	3.3	3.3	1.8	1.8
Basal cell carcinoma (self-reported)	2.5	3.0	6.0	2.5	0.1
Average weekly fortified wine intake	2.4	2.8	3.6	-1.9	1.4
Reaction Time	2.3	4.3	4.7	-2.0	-2.2
Medication for hormone replacement therapy	2.3	2.5	2.8	-1.7	1.5
Relative age voice broke	2.3	3.5	7.1	-2.7	-0.0
Neuroticism score	2.3	4.7	5.5	2.0	-2.3
Glaucoma (self-reported)	2.3	2.8	3.0	-1.6	-1.7
Allergy	2.2	5.0	5.9	-2.0	-2.4
High blood pressure (siblings)	2.2	3.1	6.1	-0.4	2.5
Mouth/teeth dental problems: Mouth ulcers	2.2	3.5	6.9	2.6	-0.2
Average weekly spirits intake	2.1	2.6	5.3	-0.0	2.3
Past tobacco smoking	2.1	3.8	7.1	-0.7	-2.7
Blood White Count	2.0	14.7	29.4	0.0	-5.4
Mouth/teeth dental problems: Loose teeth	2.0	2.3	4.5	-0.4	2.1
Hearing difficulty/problems: Yes	1.9	2.9	5.7	2.4	0.3
Alzheimer’s Disease (in mother)	1.8	2.1	3.7	-0.6	-1.9
HDL Cholesterol	1.8	3.1	5.2	2.3	-0.9
Blood Platelet Count	1.8	21.4	42.5	0.5	-6.5
Mean time to correctly identify matches	1.8	3.5	4.4	-2.1	-1.6
Smoking status: Previous	1.8	2.7	5.1	0.6	2.3
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	2.4	-1.2	1.5
Ever smoked	1.8	3.2	6.1	0.5	2.5
Alzheimer’s Disease (in father)	1.7	1.9	2.2	1.5	-1.2
Alzheimer’s Disease (including proxy)	1.7	2.4	4.7	0.3	-2.2
Triglycerides	1.7	2.8	5.2	-0.6	2.3
Financial difficulties in last 2 years	1.7	2.3	4.6	2.1	0.1
Worry too long after embarrassment	1.7	2.9	4.5	1.1	-2.1
Wheeze or whistling in the chest in last year	1.7	3.0	4.7	2.2	1.2
Osteoporosis (self-reported)	1.7	2.2	3.8	-0.7	2.0
HbA1C	1.6	1.8	2.0	-1.3	-1.4
Primary Biliary Cirrhosis	1.6	2.3	4.4	2.1	-0.5
Ever unenthusiastic/disinterested for a whole week	1.6	2.0	3.9	2.0	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	3.7	-0.1	-1.9
Blood Eosinophil Count	1.5	11.8	23.2	-0.6	-4.8
Allergy or Eczema	1.5	4.0	6.6	2.6	1.2
Heart attack	1.5	1.9	3.3	0.6	1.8
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	2.4	1.2	1.6
Heart attack/myocardial infarction (self-reported)	1.5	2.0	3.6	0.6	1.9
Neuroticism (2016)	1.4	2.0	3.8	-2.0	-0.4
Hearing difficulty/problems with background noise	1.4	2.2	4.3	2.1	0.4
Pulse rate	1.4	2.3	4.6	2.1	-0.2
Exposure to tobacco smoke at home	1.4	1.5	1.6	-1.2	-1.3
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	2.6	1.6	1.4
Illnesses of father: Heart disease	1.4	2.0	3.9	-2.0	0.3
Depression (Nagel 2018)	1.3	1.9	2.3	1.5	-1.2
Neuroticism	1.3	3.2	4.6	1.3	-2.1
Pulse wave Arterial Stiffness index	1.3	1.5	2.8	-1.7	0.4
Tense / ‘highly strung’	1.3	2.2	2.2	1.4	-1.5
Mouth/teeth dental problems: Bleeding gums	1.3	1.6	2.3	1.0	-1.5
Health satisfaction	1.3	1.7	3.2	0.4	1.8
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	2.3	0.9	1.5
Handedness (chirality/laterality): Left-handed	1.3	1.6	3.2	1.8	0.2
Age started oral contraceptive pill	1.3	1.7	2.7	-0.8	-1.7
Myopia	1.3	1.9	3.8	1.9	0.3
Worry (Nagel 2018)	1.2	2.5	3.6	1.2	-1.9
Mean Putamen Volume	1.2	1.4	2.0	-0.9	-1.4
Number of treatments/medications taken	1.2	2.2	4.5	2.1	-0.0
Taking other prescription medications	1.2	1.9	3.0	1.7	0.9
Hayfever, allergic rhinitis or eczema	1.2	2.5	3.3	1.8	1.3
Pain all over the body in last month	1.2	1.3	1.3	1.1	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.7	7.3	-2.7	0.2
Medication: Paracetamol	1.2	2.0	2.6	1.2	-1.6
Medication: Gliclazide	1.2	1.3	2.3	1.5	0.6
Ever taken oral contraceptive pill	1.2	1.3	2.7	-0.2	1.6
Maternal smoking around birth	1.1	1.6	2.3	-1.5	0.9
Diabetes (self-reported)	1.1	1.8	3.5	1.9	0.2
Worrier / anxious feelings	1.1	2.0	2.9	1.7	-1.0
Gout (self-reported)	1.1	1.5	1.5	1.2	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	1.7	1.3	-1.1
Number of full sisters	1.1	1.3	1.5	1.1	1.2
Loneliness, isolation	1.1	1.6	2.6	1.6	-0.7
Crohns Disease (2017)	1.0	2.3	3.7	-0.9	1.9
Ulcerative Colitis (UC)	1.0	1.9	3.7	-1.9	-0.0
Ever used hormone-replacement therapy (HRT)	1.0	1.2	1.9	-1.4	0.8
Had other major operations	1.0	1.2	2.2	1.5	0.4
Falls in the last year	1.0	1.3	2.2	1.5	0.7
Noisy workplace	1.0	1.2	2.5	1.6	-0.2
Birth weight of first child	1.0	1.9	2.3	1.5	1.2
Medication: Seretide 50 evohaler	1.0	1.2	2.4	0.0	1.6
Leg pain on walking	1.0	1.3	1.7	1.3	0.9
Average weekly red wine intake	1.0	1.5	2.9	-0.3	1.7
Ever had bowel cancer screening	1.0	1.2	1.4	-1.2	1.0
Breast cancer (self-reported)	1.0	1.2	2.3	-0.1	-1.5
Schizophrenia vs Biploar Disorder	0.9	1.1	2.1	-0.4	1.5
Schizophrenia (2014)	0.9	2.0	3.9	-0.4	2.0
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	3.8	-1.9	-0.7
Mouth/teeth dental problems: Dentures	0.9	1.5	2.7	0.4	1.7
Impedance of arm (left)	0.9	4.4	8.3	2.9	0.7
Blood clot in the leg (DVT)	0.9	1.2	2.4	0.2	1.5
Forced vital capacity (FVC), Best measure	0.9	3.5	6.1	-2.5	0.9
Medication: Ibuprofen	0.9	1.0	1.8	0.6	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	2.0	1.4	-0.0
Alcohol intake frequency.	0.9	2.2	3.4	1.0	-1.8
Diabetes diagnosed by doctor	0.9	1.4	2.8	1.7	0.3
Guilty feelings	0.9	1.4	2.5	0.5	-1.6
Neuroticism (Nagel 2018)	0.8	2.0	2.8	1.1	-1.7
Ovarian Cancer	0.8	1.0	1.6	-1.3	-0.7
Body Mass Index (BMI) (2010)	0.8	1.1	2.0	-0.5	-1.4
Current tobacco smoking	0.8	1.3	2.5	0.2	1.6
Mouth/teeth dental problems	0.8	1.3	2.2	-1.5	-0.5
Medication: Simvastatin	0.8	1.2	2.1	0.5	-1.4
Alcohol intake versus 10 years previously	0.8	1.2	2.1	1.5	0.5
Breastfed as a baby	0.8	1.0	1.9	0.4	-1.4
Comparative body size at age 10	0.8	2.3	3.6	1.9	1.0
Pulse rate, automated reading	0.8	2.5	2.5	1.6	1.6
Overall health rating	0.8	1.7	3.5	1.9	0.1
Commuting to job workplace: Car/motor vehicle	0.8	0.9	1.8	-0.3	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	1.8	1.3	-0.3
Average weekly champagne plus white wine intake	0.8	1.1	2.2	-1.5	-0.2
Depressed Affect (Nagel 2018)	0.7	1.4	2.5	1.6	-0.6
Rheumatoid Arthritis	0.7	0.9	1.8	1.3	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.2	1.1	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	2.2	-1.5	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.8	0.0	1.3
Depression (self-reported)	0.7	0.9	1.8	-0.0	-1.3
Pulse wave peak to peak time	0.7	0.8	1.5	1.2	-0.4
Heart disease (mother)	0.7	0.8	1.4	1.2	-0.5
Medication: Aspirin	0.7	0.9	1.8	-1.3	-0.0
Commuting to job workplace: Walk	0.7	0.7	1.1	1.0	0.6
Medication: Paracetamol	0.7	1.1	1.8	0.6	-1.4
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.7	0.4	1.3
Irritable Bowel Disease (IBD)	0.6	1.4	1.9	-1.4	1.0
Verbal and Numeric Reasoning (VNR)	0.6	1.6	2.2	1.0	-1.5
Heel T-Score	0.6	4.6	7.6	-1.3	-2.8
Sensitivity / hurt feelings	0.6	1.0	1.3	0.9	-1.1
Fed-up feelings	0.6	1.0	1.2	0.9	-1.1
Alcohol usually taken with meals	0.6	1.0	1.1	-1.0	1.0
Forced vital capacity (FVC)	0.6	2.4	2.6	-1.5	1.6
Medication: Ramipril	0.6	0.8	1.6	0.3	-1.2
Impedance of arm (right)	0.6	2.9	5.2	2.3	0.8
Prospective memory result	0.6	0.7	1.4	-1.2	-0.1
Lung cancer (father)	0.6	0.7	0.7	-0.9	0.8
Pulse wave reflection index	0.6	0.8	1.3	-1.1	0.5
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.3	1.1	-0.4
Alcohol drinker status: Never	0.6	0.7	1.2	0.3	-1.1
Risk taking	0.6	0.9	1.7	0.2	-1.3
Ulcerative Colitis	0.5	0.7	1.1	-1.0	-0.5
Medication: Metformin	0.5	0.7	1.3	0.3	1.1
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.2	-1.1	0.3
Hip circumference	0.5	2.3	2.5	1.5	-1.6
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	2.8	-1.7	0.9
Length of working week for main job	0.5	0.5	1.0	1.0	0.1
Hair/balding pattern: Pattern 4	0.5	1.2	1.8	1.3	-0.8
Peak expiratory flow (PEF)	0.5	1.3	2.2	-1.5	0.5
Loud music exposure frequency	0.5	0.6	1.1	-0.3	-1.0
Body fat percentage	0.5	1.9	3.6	1.9	-0.4
Leg fat percentage (right)	0.5	1.9	2.6	1.6	-1.1
Arm fat percentage (left)	0.5	1.8	3.3	1.8	-0.6
Mood swings	0.5	0.9	1.7	1.3	-0.3
Smoking status: Current	0.5	0.8	1.6	0.1	1.3
Miserableness	0.5	0.9	1.6	1.2	-0.5
Pain type(s) experienced in last month: Hip pain	0.5	0.6	0.7	-0.7	-0.9
Medication: Atorvastatin	0.5	0.6	1.3	-1.1	0.0
Cholesterol lowering medication	0.5	0.8	1.4	0.3	-1.2
Supplements: Calcium	0.5	0.5	1.0	-1.0	0.3
Schizophrenia (2018)	0.4	0.8	1.4	-0.5	1.2
Crohns Disease (2012)	0.4	0.6	1.1	-0.4	1.1
Lupus	0.4	0.5	1.0	0.2	-1.0
Lung FEV1/FVC ratio	0.4	1.8	3.3	-1.8	-0.5
Medication: Co-codamol	0.4	0.5	0.7	0.8	0.6
Severe depression (siblings)	0.4	0.5	0.9	0.3	0.9
Trunk fat percentage	0.4	1.8	3.5	1.9	-0.2
Stomach or abdominal pain in last month	0.4	0.5	0.8	-0.9	-0.3
Fluid intelligence score	0.4	0.9	1.4	0.6	-1.2
Trunk fat-free mass	0.4	2.2	4.2	-2.0	0.4
Father’s age at death	0.4	0.5	1.1	1.0	-0.0
Number of live births	0.4	0.6	0.8	0.9	0.6
Medication: Lansoprazole	0.4	0.4	0.8	0.0	0.9
Illnesses of mother	0.4	0.5	0.7	-0.9	-0.5
Trunk predicted mass	0.4	2.1	4.1	-2.0	0.3
Headache pain in last month	0.4	0.7	1.3	-1.1	-0.3
Chronic bronchitis/emphysema (mother)	0.4	0.5	0.9	-0.2	0.9
Exposure to tobacco smoke outside home	0.4	0.6	0.9	-0.5	-1.0
Number of full brothers	0.4	0.5	0.5	0.7	0.7
Neck or shoulder pain in last month	0.4	0.6	1.1	-1.0	-0.3
Medication: Blood pressure	0.4	0.7	1.3	0.4	-1.1
Suffer from ‘nerves’	0.4	0.6	1.0	1.0	-0.4
Supplements: Vitamin C	0.4	0.5	0.5	-0.6	-0.7
Friendships satisfaction	0.4	0.6	0.7	-0.7	-0.8
Back pain experienced in last month	0.4	0.5	0.8	0.9	0.6
Commuting to job workplace: Public transport	0.4	0.5	0.6	-0.6	0.8
Leg fat percentage (left)	0.4	1.5	1.9	1.4	-1.1
Average weekly beer plus cider intake	0.4	0.6	1.2	1.1	-0.2
Diastolic blood pressure, automated reading	0.4	1.2	2.4	-1.6	0.2
Impedance of whole body	0.4	2.0	3.9	2.0	0.2
Bipolar Disorder (2018)	0.3	0.5	0.6	0.8	-0.6
Age at First Birth	0.3	0.5	0.8	-0.9	-0.4
Fasting Glucose	0.3	0.3	0.6	-0.2	0.7
Blood Red Count	0.3	2.5	4.7	-0.5	2.2
Type 2 Diabetes (T2D) (2018)	0.3	0.6	0.8	0.9	-0.6
Chronotype (morning person)	0.3	0.7	1.2	-1.1	0.3
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.8	-0.1	-0.9
Relative age of first facial hair	0.3	0.5	0.7	-0.6	0.8
Systolic blood pressure, automated reading	0.3	0.9	1.6	-1.3	-0.3
Sitting height	0.3	2.4	4.0	-2.0	0.9
High blood pressure (mother)	0.3	0.4	0.7	-0.3	0.8
Nervous feelings	0.3	0.6	0.9	0.5	-1.0
Arm fat percentage (right)	0.3	1.3	2.3	1.5	-0.6
Time employed in main current job	0.3	0.4	0.6	0.8	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.4	0.7	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.0	0.1	-1.0
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	0.6	-0.8	0.7
Medication: Amlodipine	0.3	0.4	0.5	0.5	-0.7
Birth weight	0.3	0.6	0.9	0.6	0.9
Migraine (self-reported)	0.3	0.3	0.6	-0.8	0.3
Medication: Allopurinol	0.3	0.4	0.7	0.3	0.8
Leg fat mass (right)	0.3	1.1	1.9	1.4	-0.6
Age at last live birth	0.3	0.4	0.4	-0.7	-0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.4	-0.5	0.6
Knee pain experienced in last month	0.3	0.4	0.7	0.4	0.8
Medication: Aspirin	0.3	0.4	0.7	-0.8	0.3
Number of self-reported non-cancer illnesses	0.3	0.5	0.5	-0.7	-0.7
Arm fat-free mass (left)	0.3	1.4	2.7	-1.6	-0.2
Number of operations (self-reported)	0.3	0.5	0.9	-0.9	0.3
Vascular/heart problems diagnosed by doctor	0.3	0.7	1.5	-0.1	1.2
Arm predicted mass (left)	0.3	1.5	3.0	-1.7	-0.2
Bipolar Disorder (2011)	0.2	0.2	0.3	0.5	-0.4
Coronary Artery Disease (CAD)	0.2	0.2	0.3	-0.4	0.6
Waist Hip Ratio (WHR)	0.2	0.7	1.4	0.2	1.2
Systolic Blood Pressure	0.2	1.2	1.5	-0.9	-1.2
Vitamin and mineral supplements	0.2	0.3	0.3	0.5	-0.6
Diabetes (mother)	0.2	0.3	0.5	0.0	-0.7
Townsend deprivation index at recruitment	0.2	0.2	0.5	-0.7	-0.2
Serious illness, injury or assault to yourself	0.2	0.2	0.3	0.5	-0.5
High blood pressure	0.2	0.7	1.2	-0.3	-1.1
Multivitamins +/- minerals	0.2	0.2	0.2	0.5	0.4
Body mass index (BMI)	0.2	1.0	1.3	0.8	-1.1
Trunk fat mass	0.2	0.9	1.8	1.3	-0.1
Waist circumference	0.2	0.7	1.2	1.1	-0.5
Number of incorrect matches in round	0.2	0.4	0.7	0.8	-0.3
Hair/balding pattern: Pattern 2	0.2	0.3	0.6	0.8	-0.2
Had menopause	0.2	0.2	0.4	-0.3	0.6
Qualifications: None of the above	0.2	0.4	0.5	-0.7	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.8	0.9	-0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.4	0.7	0.9	0.3
Arm fat mass (right)	0.2	0.6	0.9	1.0	-0.6
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.5	-0.2	-0.7
Arm fat-free mass (right)	0.2	0.9	1.9	-1.4	0.2
Number of children fathered	0.2	0.3	0.4	-0.4	-0.6
Age at first live birth	0.2	0.4	0.4	-0.6	-0.6
Qualifications: College or University degree	0.2	0.5	1.0	1.0	0.1
Whole body fat mass	0.2	1.0	1.8	1.4	-0.3
Arm predicted mass (right)	0.2	1.2	2.3	-1.5	0.2
Family relationship satisfaction	0.2	0.3	0.3	-0.6	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.5	-0.7	0.6
Whole body fat-free mass	0.2	1.2	2.2	-1.5	0.4
Medication for cholesterol	0.2	0.3	0.3	0.5	-0.5
Whole body water mass	0.2	1.4	2.6	-1.6	0.4
Arm fat mass (left)	0.2	0.9	1.4	1.2	-0.7
Wears glasses or contact lenses	0.2	0.2	0.4	0.3	0.6
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.5	-0.7	0.3
Illnesses of father: High blood pressure	0.2	0.3	0.6	0.7	0.1
Irritability	0.2	0.3	0.5	-0.2	-0.7
Pain experienced in last month	0.2	0.3	0.3	0.5	-0.6
Alcohol drinker status: Previous	0.2	0.2	0.3	0.6	-0.0
Leg fat mass (left)	0.2	1.0	1.5	1.2	-0.6
Bipolar Disorder or Schizophrenia	0.1	0.2	0.3	0.1	0.6
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.1	0.3	-0.3
Cardiovascular Disease	0.1	0.4	0.7	0.2	-0.8
Lung FVC	0.1	0.5	1.0	-1.0	0.1
Hair Pigment	0.1	2.3	3.8	-0.9	1.9
Tanning	0.1	1.0	1.9	1.4	0.3
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.3	0.5	-0.3
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.1	0.3	0.3
Angina	0.1	0.1	0.1	0.3	-0.2
Diabetes (father)	0.1	0.1	0.2	-0.5	0.2
Pack years adult smoking proportion	0.1	0.2	0.2	0.3	0.5
Impedance of leg (right)	0.1	0.7	1.3	1.1	-0.2
Leg fat-free mass (left)	0.1	0.3	0.5	-0.4	0.7
Hand grip strength (right)	0.1	0.3	0.5	-0.7	0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.1	-0.4	0.3
Qualifications: CSEs or equivalent	0.1	0.1	0.2	-0.4	0.2
Supplements: Glucosamine	0.1	0.1	0.2	0.4	-0.1
Impedance of leg (left)	0.1	0.5	0.8	0.9	-0.5
Leg predicted mass (left)	0.1	0.3	0.5	-0.4	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.4	0.1	-0.6
Medication: Cholesterol lowering	0.1	0.1	0.1	-0.2	-0.3
Standing height	0.1	1.3	1.5	-1.2	1.1
Medication for pain relief, constipation, heartburn	0.1	0.2	0.5	0.7	0.1
Angina (self-reported)	0.1	0.1	0.1	0.3	-0.2
Medication: Omeprazole	0.1	0.1	0.2	0.5	0.3
Had major operations	0.1	0.1	0.1	-0.0	-0.3
Hypertension (Self-reported)	0.1	0.3	0.6	-0.2	-0.8
Leg fat-free mass (right)	0.1	0.5	0.5	-0.7	0.6
Eye problems/disorders: Cataract	0.1	0.1	0.3	0.5	0.1
Osteoarthritis (self-reported)	0.1	0.1	0.1	0.2	-0.4
Leg predicted mass (right)	0.1	0.5	0.5	-0.7	0.7
Mother’s age at death	0.1	0.1	0.2	-0.1	0.4
Financial situation satisfaction	0.1	0.1	0.1	0.2	-0.3
Medication: Blood pressure	0.1	0.1	0.1	0.3	-0.4
High cholesterol (Self-reported)	0.1	0.2	0.2	-0.5	-0.3
Medication: Bendroflumethiazide	0.1	0.2	0.3	0.5	-0.2
Medication: Lisinopril	0.1	0.2	0.3	0.5	0.3
Basal metabolic rate	0.1	0.6	1.2	-1.1	0.1
Commuting to job workplace: Cycle	0.1	0.1	0.2	0.5	-0.3
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.1	-0.1	-0.3
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	-0.1	-0.2
BMI	0.0	0.2	0.3	0.2	-0.6
Height	0.0	0.3	0.7	-0.8	0.1
Hand grip strength (left)	0.0	0.0	0.0	-0.2	-0.0
Supplements: Zinc	0.0	0.1	0.1	0.3	-0.2
Age when periods started (menarche)	0.0	0.1	0.2	0.4	-0.1
Weight	0.0	0.2	0.5	0.1	-0.7
Happiness	0.0	0.0	0.1	-0.2	0.2
Eye problems/disorders: None of the above	0.0	0.1	0.1	0.2	0.2
Comparative height size at age 10	0.0	0.0	0.1	0.1	0.3
Chest pain or discomfort	0.0	0.0	0.0	-0.1	0.2
Mineral and other dietary supplements	0.0	0.0	0.0	0.0	-0.1
Illnesses of father: None of the above (group 1)	0.0	0.0	0.1	-0.2	0.1
Hearing aid user	0.0	0.0	0.1	-0.0	0.3
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.1	0.1	-0.3
Fractured/broken bones in last 5 years	0.0	0.1	0.1	0.3	0.2
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.1	-0.1	0.3
Pack years of smoking	0.0	0.1	0.1	0.3	0.3

Hub : Genes

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