Hub : Genes

IFNG

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 NTR Blood 0.0534 0.0120 3.3e-10 0.064 0.035 0.058 0.057 0.059 9.5e-20 1.7e-11 3.7e-18 8e-18 1.7e-18
2 TCGA Kidney Renal Clear Cell Carcinoma 0.0239 0.0147 9.3e-03 0.010 0.007 -0.002 NA 0.003 2.2e-02 4.6e-02 5.9e-01 NA 1.4e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.3 0.5 0.6 0.8 -0.6
Bipolar Disorder or Schizophrenia 0.1 0.2 0.3 0.1 0.6
Depressed Affect (Nagel 2018) 0.7 1.4 2.5 1.6 -0.6
Depression (Nagel 2018) 1.3 1.9 2.3 1.5 -1.2
Intelligence (Savage-Jansen 2018) 0.0 0.1 0.1 -0.1 -0.3
Neuroticism (Nagel 2018) 0.8 2.0 2.8 1.1 -1.7
Schizophrenia (2018) 0.4 0.8 1.4 -0.5 1.2
Schizophrenia vs Biploar Disorder 0.9 1.1 2.1 -0.4 1.5
Worry (Nagel 2018) 1.2 2.5 3.6 1.2 -1.9
Alzheimer’s Disease (in mother) 1.8 2.1 3.7 -0.6 -1.9
Alzheimer’s Disease (in father) 1.7 1.9 2.2 1.5 -1.2
Alzheimer’s Disease (including proxy) 1.7 2.4 4.7 0.3 -2.2
Crohns Disease (2017) 1.0 2.3 3.7 -0.9 1.9
Irritable Bowel Disease (IBD) 0.6 1.4 1.9 -1.4 1.0
Ulcerative Colitis (UC) 1.0 1.9 3.7 -1.9 -0.0
Major Depression (MDD) 0.0 0.0 0.0 0.0 0.0
Reaction Time 2.3 4.3 4.7 -2.0 -2.2
Verbal and Numeric Reasoning (VNR) 0.6 1.6 2.2 1.0 -1.5
Breast Cancer 0.0 0.0 0.0 0.0 0.0
Ovarian Cancer 0.8 1.0 1.6 -1.3 -0.7
Prostate Cancer 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.3 0.5 0.8 -0.9 -0.4
Bipolar Disorder (2011) 0.2 0.2 0.3 0.5 -0.4
Body Mass Index (BMI) (2010) 0.8 1.1 2.0 -0.5 -1.4
Coronary Artery Disease (CAD) 0.2 0.2 0.3 -0.4 0.6
Crohns Disease (2012) 0.4 0.6 1.1 -0.4 1.1
Mean Putamen Volume 1.2 1.4 2.0 -0.9 -1.4
Fasting Glucose 0.3 0.3 0.6 -0.2 0.7
HbA1C 1.6 1.8 2.0 -1.3 -1.4
HDL Cholesterol 1.8 3.1 5.2 2.3 -0.9
LDL Cholesterol 0.0 0.0 0.0 -0.1 -0.2
Lupus 0.4 0.5 1.0 0.2 -1.0
Neuroticism (2016) 1.4 2.0 3.8 -2.0 -0.4
Primary Biliary Cirrhosis 1.6 2.3 4.4 2.1 -0.5
Rheumatoid Arthritis 0.7 0.9 1.8 1.3 -0.2
Schizophrenia (2014) 0.9 2.0 3.9 -0.4 2.0
Triglycerides 1.7 2.8 5.2 -0.6 2.3
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.1 0.3 -0.3
Ulcerative Colitis 0.5 0.7 1.1 -1.0 -0.5
Blood Eosinophil Count 1.5 11.8 23.2 -0.6 -4.8
Blood Platelet Count 1.8 21.4 42.5 0.5 -6.5
Blood Red Count 0.3 2.5 4.7 -0.5 2.2
Blood White Count 2.0 14.7 29.4 0.0 -5.4
Heel T-Score 0.6 4.6 7.6 -1.3 -2.8
BMI 0.0 0.2 0.3 0.2 -0.6
Height 0.0 0.3 0.7 -0.8 0.1
Waist Hip Ratio (WHR) 0.2 0.7 1.4 0.2 1.2
Systolic Blood Pressure 0.2 1.2 1.5 -0.9 -1.2
Smoking Status 2.8 6.7 13.2 0.3 3.6
Allergy or Eczema 1.5 4.0 6.6 2.6 1.2
Cardiovascular Disease 0.1 0.4 0.7 0.2 -0.8
Hypothyroidism (self reported) 3.8 8.7 9.2 3.0 -2.9
Respiratory disease 4.5 10.0 11.2 3.4 3.0
Type 2 Diabetes (T2D) (2018) 0.3 0.6 0.8 0.9 -0.6
Lung FEV1/FVC ratio 0.4 1.8 3.3 -1.8 -0.5
Lung FVC 0.1 0.5 1.0 -1.0 0.1
Neuroticism 1.3 3.2 4.6 1.3 -2.1
Chronotype (morning person) 0.3 0.7 1.2 -1.1 0.3
Hair Pigment 0.1 2.3 3.8 -0.9 1.9
Tanning 0.1 1.0 1.9 1.4 0.3
Hand grip strength (left) 0.0 0.0 0.0 -0.2 -0.0
Number of treatments/medications taken 1.2 2.2 4.5 2.1 -0.0
Average weekly spirits intake 2.1 2.6 5.3 -0.0 2.3
Sensitivity / hurt feelings 0.6 1.0 1.3 0.9 -1.1
Frequency of depressed mood in last 2 weeks 0.3 0.4 0.8 -0.1 -0.9
Hearing difficulty/problems: Yes 1.9 2.9 5.7 2.4 0.3
Relative age of first facial hair 0.3 0.5 0.7 -0.6 0.8
Other serious medical condition/disability diagnosed by doctor 0.1 0.2 0.3 0.5 -0.3
Ever used hormone-replacement therapy (HRT) 1.0 1.2 1.9 -1.4 0.8
Ever had hysterectomy (womb removed) 2.9 3.2 6.3 -2.5 0.4
Systolic blood pressure, automated reading 0.3 0.9 1.6 -1.3 -0.3
Eye problems/disorders: Diabetes related eye disease 0.1 0.1 0.1 0.3 0.3
Angina 0.1 0.1 0.1 0.3 -0.2
Medication for hormone replacement therapy 2.3 2.5 2.8 -1.7 1.5
Vitamin and mineral supplements 0.2 0.3 0.3 0.5 -0.6
Supplements: Zinc 0.0 0.1 0.1 0.3 -0.2
Medication: Co-codamol 0.4 0.5 0.7 0.8 0.6
Medication: Metformin 0.5 0.7 1.3 0.3 1.1
Diabetes (father) 0.1 0.1 0.2 -0.5 0.2
Diabetes (mother) 0.2 0.3 0.5 0.0 -0.7
Severe depression (siblings) 0.4 0.5 0.9 0.3 0.9
Pack years adult smoking proportion 0.1 0.2 0.2 0.3 0.5
Impedance of leg (right) 0.1 0.7 1.3 1.1 -0.2
Leg fat-free mass (left) 0.1 0.3 0.5 -0.4 0.7
Trunk fat percentage 0.4 1.8 3.5 1.9 -0.2
Hand grip strength (right) 0.1 0.3 0.5 -0.7 0.1
Townsend deprivation index at recruitment 0.2 0.2 0.5 -0.7 -0.2
Current tobacco smoking 0.8 1.3 2.5 0.2 1.6
Average weekly fortified wine intake 2.4 2.8 3.6 -1.9 1.4
Maternal smoking around birth 1.1 1.6 2.3 -1.5 0.9
Fed-up feelings 0.6 1.0 1.2 0.9 -1.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 0.9 1.2 1.1 -0.8
Relative age voice broke 2.3 3.5 7.1 -2.7 -0.0
Taking other prescription medications 1.2 1.9 3.0 1.7 0.9
Age when periods started (menarche) 0.0 0.1 0.2 0.4 -0.1
Bilateral oophorectomy (both ovaries removed) 3.2 3.7 4.3 -1.7 2.1
Heel bone mineral density (BMD) T-score, automated (left) 0.9 2.1 3.8 -1.9 -0.7
Tinnitus: Yes, but not now, but have in the past 0.1 0.1 0.1 -0.4 0.3
Qualifications: CSEs or equivalent 0.1 0.1 0.2 -0.4 0.2
Serious illness, injury or assault to yourself 0.2 0.2 0.3 0.5 -0.5
High blood pressure 0.2 0.7 1.2 -0.3 -1.1
Hayfever, allergic rhinitis or eczema 1.2 2.5 3.3 1.8 1.3
Multivitamins +/- minerals 0.2 0.2 0.2 0.5 0.4
Stomach or abdominal pain in last month 0.4 0.5 0.8 -0.9 -0.3
Supplements: Glucosamine 0.1 0.1 0.2 0.4 -0.1
Diverticular disease/diverticulitis (self-reported) 0.5 0.6 1.2 -1.1 0.3
Medication: Atenolol 3.1 3.9 6.3 1.2 -2.5
Medication: Levothyroxine sodium 3.2 5.4 6.3 2.1 -2.5
Sitting height 0.3 2.4 4.0 -2.0 0.9
Chronic bronchitis/emphysema (father) 2.8 3.3 6.2 2.5 0.6
High blood pressure (mother) 0.3 0.4 0.7 -0.3 0.8
Body mass index (BMI) 0.2 1.0 1.3 0.8 -1.1
Impedance of leg (left) 0.1 0.5 0.8 0.9 -0.5
Leg predicted mass (left) 0.1 0.3 0.5 -0.4 0.7
Trunk fat mass 0.2 0.9 1.8 1.3 -0.1
Waist circumference 0.2 0.7 1.2 1.1 -0.5
Number of incorrect matches in round 0.2 0.4 0.7 0.8 -0.3
Past tobacco smoking 2.1 3.8 7.1 -0.7 -2.7
Alcohol usually taken with meals 0.6 1.0 1.1 -1.0 1.0
Nervous feelings 0.3 0.6 0.9 0.5 -1.0
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 0.4 0.1 -0.6
Hearing difficulty/problems with background noise 1.4 2.2 4.3 2.1 0.4
Hair/balding pattern: Pattern 2 0.2 0.3 0.6 0.8 -0.2
Had menopause 0.2 0.2 0.4 -0.3 0.6
Had other major operations 1.0 1.2 2.2 1.5 0.4
Forced vital capacity (FVC) 0.6 2.4 2.6 -1.5 1.6
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.5 2.2 -1.5 -0.9
Ever unenthusiastic/disinterested for a whole week 1.6 2.0 3.9 2.0 0.2
Qualifications: None of the above 0.2 0.4 0.5 -0.7 -0.5
Financial difficulties in last 2 years 1.7 2.3 4.6 2.1 0.1
Mouth/teeth dental problems 0.8 1.3 2.2 -1.5 -0.5
Heart attack 1.5 1.9 3.3 0.6 1.8
Allergy 2.2 5.0 5.9 -2.0 -2.4
Pain all over the body in last month 1.2 1.3 1.3 1.1 1.1
Diabetes (self-reported) 1.1 1.8 3.5 1.9 0.2
Hayfever/allergic rhinitis (self-reported) 1.5 2.0 2.4 1.2 1.6
Medication: Ramipril 0.6 0.8 1.6 0.3 -1.2
Medication: Simvastatin 0.8 1.2 2.1 0.5 -1.4
Fluid intelligence score 0.4 0.9 1.4 0.6 -1.2
Illnesses of siblings 4.1 5.8 11.6 0.0 -3.4
Neuroticism score 2.3 4.7 5.5 2.0 -2.3
Weight 0.0 0.2 0.5 0.1 -0.7
Impedance of arm (right) 0.6 2.9 5.2 2.3 0.8
Arm fat percentage (right) 0.3 1.3 2.3 1.5 -0.6
Trunk fat-free mass 0.4 2.2 4.2 -2.0 0.4
Hip circumference 0.5 2.3 2.5 1.5 -1.6
Time employed in main current job 0.3 0.4 0.6 0.8 -0.4
Alcohol intake versus 10 years previously 0.8 1.2 2.1 1.5 0.5
Father’s age at death 0.4 0.5 1.1 1.0 -0.0
Worrier / anxious feelings 1.1 2.0 2.9 1.7 -1.0
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.4 0.8 0.9 -0.1
Falls in the last year 1.0 1.3 2.2 1.5 0.7
Hair/balding pattern: Pattern 3 5.4 8.0 15.6 -3.9 0.7
Number of live births 0.4 0.6 0.8 0.9 0.6
Forced expiratory volume in 1-second (FEV1) 0.5 1.8 2.8 -1.7 0.9
Pulse rate 1.4 2.3 4.6 2.1 -0.2
Happiness 0.0 0.0 0.1 -0.2 0.2
Noisy workplace 1.0 1.2 2.5 1.6 -0.2
Qualifications: A levels/AS levels or equivalent 0.2 0.4 0.7 0.9 0.3
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 0.4 0.7 -0.4
Mouth/teeth dental problems: Dentures 0.9 1.5 2.7 0.4 1.7
Asthma 4.0 7.9 12.4 1.8 3.5
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 1.8 0.0 1.3
Medication: Cholesterol lowering 0.1 0.1 0.1 -0.2 -0.3
Depression (self-reported) 0.7 0.9 1.8 -0.0 -1.3
Medication: Lansoprazole 0.4 0.4 0.8 0.0 0.9
Prospective memory result 0.6 0.7 1.4 -1.2 -0.1
Lung cancer (father) 0.6 0.7 0.7 -0.9 0.8
Illnesses of mother 0.4 0.5 0.7 -0.9 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 1.2 3.7 7.3 -2.7 0.2
Pulse wave Arterial Stiffness index 1.3 1.5 2.8 -1.7 0.4
Impedance of arm (left) 0.9 4.4 8.3 2.9 0.7
Arm fat mass (right) 0.2 0.6 0.9 1.0 -0.6
Trunk predicted mass 0.4 2.1 4.1 -2.0 0.3
Standing height 0.1 1.3 1.5 -1.2 1.1
Length of working week for main job 0.5 0.5 1.0 1.0 0.1
Exposure to tobacco smoke at home 1.4 1.5 1.6 -1.2 -1.3
Breastfed as a baby 0.8 1.0 1.9 0.4 -1.4
Tense / ‘highly strung’ 1.3 2.2 2.2 1.4 -1.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 1.0 0.1 -1.0
Hair/balding pattern: Pattern 4 0.5 1.2 1.8 1.3 -0.8
Birth weight of first child 1.0 1.9 2.3 1.5 1.2
Peak expiratory flow (PEF) 0.5 1.3 2.2 -1.5 0.5
Pulse wave reflection index 0.6 0.8 1.3 -1.1 0.5
Ever highly irritable/argumentative for 2 days 0.2 0.3 0.5 -0.2 -0.7
Loud music exposure frequency 0.5 0.6 1.1 -0.3 -1.0
Qualifications: O levels/GCSEs or equivalent 1.4 2.2 2.6 1.6 1.4
Mouth/teeth dental problems: Bleeding gums 1.3 1.6 2.3 1.0 -1.5
Blood clot in the leg (DVT) 0.9 1.2 2.4 0.2 1.5
Medication: Paracetamol 1.2 2.0 2.6 1.2 -1.6
Headache pain in last month 0.4 0.7 1.3 -1.1 -0.3
Medication for cholesterol, blood pressure or diabetes 0.3 0.6 0.6 -0.8 0.7
Glaucoma (self-reported) 2.3 2.8 3.0 -1.6 -1.7
Gout (self-reported) 1.1 1.5 1.5 1.2 1.2
Hypothyroidism/myxoedema (self-reported) 2.8 5.5 7.3 1.9 -2.7
Medication: Amlodipine 0.3 0.4 0.5 0.5 -0.7
Medication: Ventolin 100micrograms inhaler 4.7 6.1 6.5 2.5 2.4
Birth weight 0.3 0.6 0.9 0.6 0.9
Chronic bronchitis/emphysema (mother) 0.4 0.5 0.9 -0.2 0.9
High blood pressure (siblings) 2.2 3.1 6.1 -0.4 2.5
Forced vital capacity (FVC), Best measure 0.9 3.5 6.1 -2.5 0.9
Body fat percentage 0.5 1.9 3.6 1.9 -0.4
Leg fat percentage (right) 0.5 1.9 2.6 1.6 -1.1
Arm fat-free mass (right) 0.2 0.9 1.9 -1.4 0.2
Exposure to tobacco smoke outside home 0.4 0.6 0.9 -0.5 -1.0
Comparative body size at age 10 0.8 2.3 3.6 1.9 1.0
Number of full brothers 0.4 0.5 0.5 0.7 0.7
Worry too long after embarrassment 1.7 2.9 4.5 1.1 -2.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.1 1.5 1.7 1.3 -1.1
Wheeze or whistling in the chest in last year 1.7 3.0 4.7 2.2 1.2
Number of children fathered 0.2 0.3 0.4 -0.4 -0.6
Reason for reducing amount of alcohol drunk: Health precaution 4.0 4.7 9.0 3.0 0.6
Age at first live birth 0.2 0.4 0.4 -0.6 -0.6
Pulse wave peak to peak time 0.7 0.8 1.5 1.2 -0.4
Health satisfaction 1.3 1.7 3.2 0.4 1.8
Shortness of breath walking on level ground 3.0 3.6 6.2 1.0 2.5
Qualifications: College or University degree 0.2 0.5 1.0 1.0 0.1
Eye problems/disorders: None of the above 0.0 0.1 0.1 0.2 0.2
Mouth/teeth dental problems: Loose teeth 2.0 2.3 4.5 -0.4 2.1
Emphysema/chronic bronchitis 2.8 3.2 6.4 0.1 2.5
Medication for pain relief, constipation, heartburn 0.1 0.2 0.5 0.7 0.1
Neck or shoulder pain in last month 0.4 0.6 1.1 -1.0 -0.3
Medication: Blood pressure 0.4 0.7 1.3 0.4 -1.1
Angina (self-reported) 0.1 0.1 0.1 0.3 -0.2
Migraine (self-reported) 0.3 0.3 0.6 -0.8 0.3
Medication: Ibuprofen 0.9 1.0 1.8 0.6 1.3
Medication: Allopurinol 0.3 0.4 0.7 0.3 0.8
Medication: Omeprazole 0.1 0.1 0.2 0.5 0.3
Medication: Seretide 50 evohaler 1.0 1.2 2.4 0.0 1.6
Mean time to correctly identify matches 1.8 3.5 4.4 -2.1 -1.6
Heart disease (mother) 0.7 0.8 1.4 1.2 -0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.0 2.0 1.4 -0.0
Whole body fat mass 0.2 1.0 1.8 1.4 -0.3
Leg fat mass (right) 0.3 1.1 1.9 1.4 -0.6
Arm predicted mass (right) 0.2 1.2 2.3 -1.5 0.2
Pulse rate, automated reading 0.8 2.5 2.5 1.6 1.6
Alcohol intake frequency. 0.9 2.2 3.4 1.0 -1.8
Comparative height size at age 10 0.0 0.0 0.1 0.1 0.3
Number of full sisters 1.1 1.3 1.5 1.1 1.2
Suffer from ‘nerves’ 0.4 0.6 1.0 1.0 -0.4
Overall health rating 0.8 1.7 3.5 1.9 0.1
Chest pain or discomfort 0.0 0.0 0.0 -0.1 0.2
Had major operations 0.1 0.1 0.1 -0.0 -0.3
Age at last live birth 0.3 0.4 0.4 -0.7 -0.6
Family relationship satisfaction 0.2 0.3 0.3 -0.6 -0.4
Leg pain on walking 1.0 1.3 1.7 1.3 0.9
Qualifications: NVQ or HND or HNC or equivalent 1.3 1.5 2.3 0.9 1.5
Commuting to job workplace: Car/motor vehicle 0.8 0.9 1.8 -0.3 -1.3
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 0.4 -0.5 0.6
Medication: Aspirin 0.7 0.9 1.8 -1.3 -0.0
Supplements: Vitamin C 0.4 0.5 0.5 -0.6 -0.7
Knee pain experienced in last month 0.3 0.4 0.7 0.4 0.8
Hypertension (Self-reported) 0.1 0.3 0.6 -0.2 -0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 1.8 1.3 -0.3
Illnesses of father: Heart disease 1.4 2.0 3.9 -2.0 0.3
Illnesses of siblings: Diabetes 3.2 4.0 4.8 1.8 2.2
Smoking status: Previous 1.8 2.7 5.1 0.6 2.3
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 0.5 -0.7 0.6
Whole body fat-free mass 0.2 1.2 2.2 -1.5 0.4
Leg fat-free mass (right) 0.1 0.5 0.5 -0.7 0.6
Arm fat percentage (left) 0.5 1.8 3.3 1.8 -0.6
Average weekly red wine intake 1.0 1.5 2.9 -0.3 1.7
Handedness (chirality/laterality): Left-handed 1.3 1.6 3.2 1.8 0.2
Mood swings 0.5 0.9 1.7 1.3 -0.3
Loneliness, isolation 1.1 1.6 2.6 1.6 -0.7
Long-standing illness, disability or infirmity 2.9 4.5 8.9 3.0 0.3
Ever had bowel cancer screening 1.0 1.2 1.4 -1.2 1.0
Diabetes diagnosed by doctor 0.9 1.4 2.8 1.7 0.3
Ever had stillbirth, spontaneous miscarriage or termination 1.8 1.9 2.4 -1.2 1.5
Friendships satisfaction 0.4 0.6 0.7 -0.7 -0.8
Qualifications: nursing, teaching 2.6 4.1 7.0 -1.1 -2.6
Commuting to job workplace: Walk 0.7 0.7 1.1 1.0 0.6
Eye problems/disorders: Cataract 0.1 0.1 0.3 0.5 0.1
Mouth/teeth dental problems: Mouth ulcers 2.2 3.5 6.9 2.6 -0.2
Medication for cholesterol 0.2 0.3 0.3 0.5 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.6 1.9 3.7 -0.1 -1.9
Back pain experienced in last month 0.4 0.5 0.8 0.9 0.6
Mineral and other dietary supplements 0.0 0.0 0.0 0.0 -0.1
Breast cancer (self-reported) 1.0 1.2 2.3 -0.1 -1.5
Asthma (self-reported) 4.5 9.0 13.8 2.0 3.7
Osteoporosis (self-reported) 1.7 2.2 3.8 -0.7 2.0
Osteoarthritis (self-reported) 0.1 0.1 0.1 0.2 -0.4
Medication: Aspirin 0.3 0.4 0.7 -0.8 0.3
Medication: Gliclazide 1.2 1.3 2.3 1.5 0.6
Illnesses of father: None of the above (group 1) 0.0 0.0 0.1 -0.2 0.1
Smoking status: Current 0.5 0.8 1.6 0.1 1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 3.4 7.1 11.0 -1.8 -3.3
Whole body water mass 0.2 1.4 2.6 -1.6 0.4
Leg predicted mass (right) 0.1 0.5 0.5 -0.7 0.7
Arm fat mass (left) 0.2 0.9 1.4 1.2 -0.7
Number of self-reported non-cancer illnesses 0.3 0.5 0.5 -0.7 -0.7
Average weekly champagne plus white wine intake 0.8 1.1 2.2 -1.5 -0.2
Miserableness 0.5 0.9 1.6 1.2 -0.5
Guilty feelings 0.9 1.4 2.5 0.5 -1.6
Wears glasses or contact lenses 0.2 0.2 0.4 0.3 0.6
Ever taken oral contraceptive pill 1.2 1.3 2.7 -0.2 1.6
Hearing aid user 0.0 0.0 0.1 -0.0 0.3
Mother’s age at death 0.1 0.1 0.2 -0.1 0.4
Financial situation satisfaction 0.1 0.1 0.1 0.2 -0.3
Tinnitus: Yes, now most or all of the time 0.6 0.7 1.3 1.1 -0.4
Commuting to job workplace: Public transport 0.4 0.5 0.6 -0.6 0.8
Eye problems/disorders: Glaucoma 2.5 2.9 3.3 -1.6 -1.8
Medication: Blood pressure 0.1 0.1 0.1 0.3 -0.4
Pain type(s) experienced in last month: Hip pain 0.5 0.6 0.7 -0.7 -0.9
Supplements: Fish oil (including cod liver oil) 0.2 0.3 0.5 -0.7 0.3
High cholesterol (Self-reported) 0.1 0.2 0.2 -0.5 -0.3
Medication: Bendroflumethiazide 0.1 0.2 0.3 0.5 -0.2
Medication: Paracetamol 0.7 1.1 1.8 0.6 -1.4
Medication: Lisinopril 0.1 0.2 0.3 0.5 0.3
Medication: Atorvastatin 0.5 0.6 1.3 -1.1 0.0
Illnesses of father: High blood pressure 0.2 0.3 0.6 0.7 0.1
Alcohol drinker status: Never 0.6 0.7 1.2 0.3 -1.1
Ever smoked 1.8 3.2 6.1 0.5 2.5
Basal metabolic rate 0.1 0.6 1.2 -1.1 0.1
Leg fat percentage (left) 0.4 1.5 1.9 1.4 -1.1
Arm fat-free mass (left) 0.3 1.4 2.7 -1.6 -0.2
Number of operations (self-reported) 0.3 0.5 0.9 -0.9 0.3
Average weekly beer plus cider intake 0.4 0.6 1.2 1.1 -0.2
Irritability 0.2 0.3 0.5 -0.2 -0.7
Risk taking 0.6 0.9 1.7 0.2 -1.3
Ever had prostate specific antigen (PSA) test 0.0 0.0 0.1 0.1 -0.3
Fractured/broken bones in last 5 years 0.0 0.1 0.1 0.3 0.2
Age started oral contraceptive pill 1.3 1.7 2.7 -0.8 -1.7
Diastolic blood pressure, automated reading 0.4 1.2 2.4 -1.6 0.2
Ever depressed for a whole week 2.5 3.0 5.8 2.4 -0.5
Unable to work because of sickness or disability 2.5 3.3 3.3 1.8 1.8
Commuting to job workplace: Cycle 0.1 0.1 0.2 0.5 -0.3
Myopia 1.3 1.9 3.8 1.9 0.3
Vascular/heart problems diagnosed by doctor 0.3 0.7 1.5 -0.1 1.2
Cholesterol lowering medication 0.5 0.8 1.4 0.3 -1.2
Medication: Omeprazole (e.g. Zanprol) 0.0 0.0 0.1 -0.1 0.3
Pain experienced in last month 0.2 0.3 0.3 0.5 -0.6
Supplements: Calcium 0.5 0.5 1.0 -1.0 0.3
Basal cell carcinoma (self-reported) 2.5 3.0 6.0 2.5 0.1
Heart attack/myocardial infarction (self-reported) 1.5 2.0 3.6 0.6 1.9
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 1.7 0.4 1.3
Heart disease (siblings) 6.0 7.3 14.4 -0.5 3.8
Alcohol drinker status: Previous 0.2 0.2 0.3 0.6 -0.0
Pack years of smoking 0.0 0.1 0.1 0.3 0.3
Impedance of whole body 0.4 2.0 3.9 2.0 0.2
Leg fat mass (left) 0.2 1.0 1.5 1.2 -0.6
Arm predicted mass (left) 0.3 1.5 3.0 -1.7 -0.2