TWAS hub - IL20RB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1430	0.0490	2.6e-05	0.021	NA	0.015	NA	0.028	7.0e-03	NA	1.9e-02	NA	2.4e-03
2	GTEx	Artery Tibial	0.2266	0.0641	6.7e-06	0.074	NA	0.059	NA	0.044	2.1e-06	NA	1.9e-05	NA	2.0e-04
3	GTEx	Cells Transformed fibroblasts	0.3510	0.0650	0.0e+00	0.162	NA	0.313	NA	0.290	3.6e-12	NA	6.0e-24	NA	5.0e-22
4	GTEx	Esophagus Mucosa	0.1460	0.0460	1.4e-06	0.117	NA	0.088	NA	0.097	3.3e-08	NA	1.7e-06	NA	5.3e-07
5	GTEx	Esophagus Muscularis	0.1120	0.0510	3.8e-03	0.089	NA	0.068	NA	0.069	4.6e-06	NA	6.3e-05	NA	5.1e-05
6	GTEx	Nerve Tibial	0.3497	0.0727	8.2e-13	0.219	NA	0.168	NA	0.187	1.6e-15	NA	5.5e-12	NA	2.9e-13
7	GTEx	Skin Not Sun Exposed Suprapubic	0.2160	0.0610	1.3e-09	0.155	NA	0.175	NA	0.190	7.6e-09	NA	7.3e-10	NA	1.2e-10
8	GTEx	Skin Sun Exposed Lower leg	0.1620	0.0510	6.6e-09	0.080	NA	0.097	NA	0.140	3.8e-07	NA	2.1e-08	NA	1.2e-11
9	METSIM	Adipose	0.1523	0.0557	8.1e-07	0.000	0.049	0.040	0.059	0.011	3.8e-01	6.2e-08	9.3e-07	3.4e-09	6.4e-03
10	TCGA	Breast Invasive Carcinoma	0.0290	0.0133	1.9e-05	0.011	0.019	0.009	NA	0.015	1.8e-03	6.3e-05	4.9e-03	NA	3.1e-04
11	TCGA	Head and Neck Squamous Cell Carcinoma	0.1248	0.0450	1.0e-05	0.071	0.056	0.057	NA	0.069	2.0e-08	6.2e-07	5.0e-07	NA	3.3e-08
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.0615	0.0363	4.1e-03	0.005	0.013	0.014	NA	0.005	8.9e-02	1.2e-02	8.8e-03	NA	7.1e-02
13	TCGA	Lung Adenocarcinoma	0.0674	0.0309	3.0e-04	0.001	0.014	0.016	NA	0.007	2.2e-01	7.8e-03	4.4e-03	NA	4.5e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Had other major operations	6.6	8.1	13.1	3.6	3.4	3.0	3.3	3.2	3.6	0.7	1.6	2.3	3.3	3.2	1.5	2.3
Alzheimer’s Disease (including proxy)	6.4	9.3	15.3	3.9	3.1	3.3	3.8	3.5	3.5	2.7	3.1	1.8	2.5	3.2	2.9	1.0
Pain type(s) experienced in last month: Hip pain	5.4	6.9	12.7	2.6	2.2	3.3	3.6	2.8	2.7	2.5	3.0	2.5	1.5	2.6	2.9	0.3
Medication: Lansoprazole	4.4	5.1	10.2	1.7	1.7	3.1	2.7	2.2	2.3	2.5	2.5	2.0	1.7	2.0	3.2	0.2
Mouth/teeth dental problems: Bleeding gums	4.0	5.2	8.6	2.3	2.1	2.7	2.5	2.8	2.9	1.2	1.9	1.2	1.6	2.9	2.4	2.1
Alzheimer’s Disease (in father)	3.9	4.2	7.5	2.5	2.3	2.4	2.7	2.5	2.5	1.3	1.6	0.5	1.8	2.5	1.6	1.0
Medication for hormone replacement therapy	3.9	4.4	7.8	2.0	2.3	2.2	2.8	2.5	2.2	1.4	2.2	2.3	1.1	2.4	2.1	0.8
Diabetes (self-reported)	3.8	5.8	12.9	1.8	2.0	3.6	2.9	2.5	2.6	2.4	2.3	2.2	1.7	2.4	3.2	0.8
Suffer from ‘nerves’	3.8	6.0	14.0	-3.1	-1.9	-1.0	-2.0	-2.8	-2.6	1.3	0.1	-3.0	-3.7	-2.9	-1.2	-3.1
High blood pressure (mother)	3.7	5.2	8.4	-2.6	-2.0	-2.3	-2.9	-2.7	-2.9	-2.0	-2.4	-1.3	-1.0	-2.7	-1.9	-1.9
Hair/balding pattern: Pattern 2	3.6	4.5	9.7	-2.8	-1.3	-2.9	-2.1	-1.7	-2.5	-3.0	-3.1	-0.0	-1.5	-1.6	-1.9	0.1
Medication: Metformin	3.5	4.9	10.5	1.8	1.2	3.2	2.5	2.2	2.2	2.4	2.3	2.4	1.9	2.0	2.8	0.2
Diabetes diagnosed by doctor	3.3	5.5	11.5	1.6	1.3	3.4	2.9	2.4	2.4	2.0	2.0	2.7	2.4	2.3	2.9	0.7
Bipolar Disorder (2011)	3.1	3.0	6.0	-2.4	-1.9	-1.8	-1.9	-1.9	-1.7	-1.4	-1.8	-1.8	-1.5	-1.8	-1.5	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	2.9	3.8	14.2	-0.9	0.4	2.2	0.8	-0.7	-0.9	3.7	2.8	0.7	-1.3	-1.2	1.6	-3.8
Mouth/teeth dental problems	2.9	4.4	8.9	-0.9	-2.0	-2.8	-1.9	-1.8	-1.7	-2.9	-2.9	-2.4	-0.9	-1.6	-3.0	0.6
Commuting to job workplace: Cycle	2.9	3.5	7.6	2.5	1.1	1.2	2.3	2.5	2.0	0.4	0.8	2.1	2.8	2.3	1.7	0.9
Neuroticism	2.8	6.6	28.6	-0.4	0.1	3.2	1.3	-0.5	-0.2	5.3	4.2	0.6	-1.8	-0.9	2.7	-4.0
Other serious medical condition/disability diagnosed by doctor	2.8	3.6	7.4	2.0	1.5	2.4	2.7	2.3	2.4	0.1	0.7	1.2	2.7	2.3	0.9	1.2
Nervous feelings	2.7	5.1	17.2	-1.8	-0.6	1.9	0.2	-1.2	-0.9	4.2	3.2	-1.1	-3.7	-1.4	1.7	-3.1
Frequency of tenseness / restlessness in last 2 weeks	2.7	4.1	15.5	-1.2	0.1	2.0	0.3	-1.0	-1.1	3.8	2.8	-0.2	-2.1	-1.3	1.2	-3.9
Worrier / anxious feelings	2.7	5.1	18.6	-0.5	0.2	2.7	1.3	0.2	0.1	4.3	3.8	1.3	-2.0	-0.3	2.9	-3.1
Diastolic blood pressure, automated reading	2.6	8.1	12.5	-3.0	-2.4	-3.5	-3.5	-3.1	-3.4	-2.6	-3.3	-1.7	-1.6	-3.1	-2.9	-1.9
Worry (Nagel 2018)	2.5	5.2	21.4	-1.2	0.2	2.6	1.0	-0.6	-0.4	4.6	3.5	-0.1	-2.5	-1.0	2.5	-3.3
Alzheimer’s Disease (in mother)	2.5	3.0	5.6	2.4	1.7	1.7	2.0	1.8	1.8	1.9	2.0	1.3	0.9	1.6	1.8	0.7
Fed-up feelings	2.5	4.6	20.3	-1.8	-1.4	0.5	-0.6	-1.8	-2.1	3.2	2.2	0.1	-2.3	-2.1	0.9	-4.5
Hayfever/allergic rhinitis (self-reported)	2.5	3.4	4.5	-1.9	-1.9	-2.1	-2.1	-1.9	-2.1	-1.3	-1.5	-2.1	-1.8	-1.7	-2.1	-0.7
Breast cancer (self-reported)	2.5	3.0	5.9	-2.2	-1.4	-1.7	-1.7	-1.7	-2.0	-2.0	-2.4	-0.9	-0.6	-1.6	-2.2	-0.8
Average weekly beer plus cider intake	2.5	3.6	15.1	-1.9	-2.0	-0.9	-1.8	-2.1	-2.3	0.4	-0.7	-1.0	-1.3	-2.4	-0.9	-3.9
Depression (Nagel 2018)	2.4	3.6	12.8	-0.8	0.2	2.7	0.9	-0.9	-0.7	3.5	2.3	0.1	-1.1	-1.2	1.9	-3.6
Hand grip strength (right)	2.4	6.5	9.6	-3.1	-2.8	-2.5	-3.0	-2.7	-2.7	-1.8	-2.4	-3.0	-2.6	-2.6	-2.2	-1.0
Tense / ‘highly strung’	2.4	4.0	11.7	-1.5	-1.5	1.4	0.4	-1.0	-1.1	3.4	2.9	-0.7	-3.3	-1.2	1.5	-2.8
Mean Putamen Volume	2.3	2.7	4.2	1.9	0.7	1.6	2.0	2.0	1.9	0.4	1.1	1.9	0.8	1.9	1.7	2.1
Type 2 Diabetes (T2D) (2018)	2.3	4.2	8.1	1.7	1.3	2.8	2.4	2.4	2.2	0.5	0.9	2.3	2.8	2.3	2.2	1.5
Medication: Co-codamol	2.3	2.7	6.2	-2.2	-1.2	-1.5	-1.9	-2.1	-2.3	-0.2	-1.2	0.2	-0.5	-2.0	-1.1	-2.5
Medication: Simvastatin	2.3	3.3	7.4	-1.8	-0.7	-2.4	-2.4	-1.6	-2.0	-2.5	-2.7	0.6	1.5	-1.6	-1.5	-0.5
Standing height	2.3	22.7	39.9	-4.4	-4.2	-5.0	-4.8	-4.1	-3.2	-6.3	-6.0	-5.5	-4.6	-3.2	-5.6	3.9
Medication: Ventolin 100micrograms inhaler	2.3	2.9	5.8	1.2	1.2	1.9	1.9	1.9	1.6	1.7	2.1	2.1	0.6	1.7	2.4	0.4
Mean time to correctly identify matches	2.3	4.3	12.0	2.1	1.1	2.9	2.4	1.4	1.7	3.4	3.5	1.8	0.2	1.3	1.8	-0.6
Schizophrenia (2018)	2.2	4.7	13.9	-1.7	-2.1	0.7	-0.7	-1.8	-1.6	3.4	2.2	-1.9	-3.0	-2.0	-0.1	-3.7
Neuroticism (2016)	2.2	3.2	10.6	-1.6	-1.1	0.5	-0.6	-1.8	-1.4	2.6	1.7	-1.4	-2.5	-1.8	0.0	-3.3
Height	2.2	42.9	74.1	-5.5	-5.8	-7.8	-6.3	-5.2	-4.4	-8.6	-7.6	-7.4	-6.8	-4.0	-8.1	5.6
Systolic blood pressure, automated reading	2.2	6.5	10.7	-2.6	-2.4	-3.3	-3.2	-3.0	-3.0	-2.5	-3.1	-1.4	-0.9	-2.8	-2.5	-1.1
Neuroticism score	2.2	4.6	16.5	-1.3	-1.1	1.6	0.5	-1.2	-1.1	4.1	3.1	-0.3	-2.4	-1.4	1.5	-3.9
Forced expiratory volume in 1-second (FEV1)	2.2	7.3	15.4	-3.0	-2.3	-2.2	-2.8	-2.7	-2.8	-1.8	-2.6	-3.9	-2.9	-2.7	-2.9	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.2	2.5	4.0	1.3	1.4	1.7	2.0	1.8	1.7	1.5	1.8	1.5	0.9	1.8	1.9	0.9
Friendships satisfaction	2.2	2.8	5.3	1.7	1.7	2.3	2.2	1.7	1.7	1.3	1.6	1.5	1.1	1.5	2.0	0.9
Illnesses of father: None of the above (group 1)	2.2	2.8	6.2	-1.8	-2.1	-1.8	-1.4	-2.0	-2.1	-0.2	-0.6	-1.3	-2.5	-2.0	-1.5	-0.5
Neuroticism (Nagel 2018)	2.1	5.0	19.1	-1.0	-0.4	2.0	0.6	-1.0	-0.9	4.4	3.2	0.1	-1.8	-1.4	2.2	-4.1
Stomach or abdominal pain in last month	2.1	2.6	14.3	-1.5	-1.2	0.4	-0.4	-1.5	-1.7	1.8	0.4	-0.9	-1.8	-1.7	-0.2	-3.8
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.8	12.1	-3.2	-2.2	-2.2	-2.5	-2.8	-2.8	-1.5	-2.3	-3.5	-3.4	-2.7	-2.6	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.3	7.0	-2.4	-1.6	-2.4	-1.9	-2.1	-2.1	-2.6	-2.6	-1.5	-2.3	-1.8	-2.2	0.9
Asthma (self-reported)	2.1	4.1	7.7	1.4	2.0	2.8	2.3	2.3	2.2	1.4	1.8	2.2	1.5	2.3	2.5	0.8
Medication: Bendroflumethiazide	2.1	3.1	7.3	-1.2	-1.4	-2.2	-2.3	-2.1	-1.7	-2.4	-2.7	0.1	0.6	-1.8	-1.9	0.2
Schizophrenia vs Biploar Disorder	2.0	2.6	6.6	1.4	0.8	2.2	1.5	1.0	1.1	2.2	2.4	2.6	0.4	0.9	2.0	-0.2
Crohns Disease (2017)	2.0	4.3	7.8	-1.9	-2.8	-2.6	-2.1	-2.3	-2.4	-2.0	-2.3	-1.1	-1.9	-2.0	-2.1	-0.3
Major Depression (MDD)	2.0	2.4	11.0	-1.1	-1.5	0.3	-1.2	-2.1	-1.4	1.0	-0.2	-1.1	-0.4	-2.4	-0.8	-3.3
Frequency of depressed mood in last 2 weeks	2.0	2.9	12.8	-0.7	-0.1	2.2	0.8	-1.1	-0.9	2.9	1.9	-0.2	-1.3	-1.3	0.8	-3.6
Overall health rating	2.0	4.3	9.7	1.3	2.6	2.7	2.4	1.9	1.7	1.7	1.6	3.1	1.9	1.7	2.6	-0.3
High cholesterol (Self-reported)	2.0	3.6	7.8	-2.1	-0.9	-2.0	-2.8	-2.2	-2.3	-1.8	-2.4	-0.6	0.7	-2.4	-1.3	-1.6
Forced vital capacity (FVC)	1.9	7.4	17.6	-3.2	-2.6	-2.1	-2.7	-2.6	-2.8	-1.6	-2.6	-4.2	-2.8	-2.6	-2.8	-1.7
Mouth/teeth dental problems: Dentures	1.9	3.1	10.6	0.5	1.3	2.1	1.3	0.4	0.3	3.2	3.0	1.6	-0.2	0.1	2.0	-2.5
Osteoarthritis (self-reported)	1.9	2.5	6.4	1.8	0.5	1.7	1.4	1.1	1.2	2.5	2.3	1.6	1.1	1.0	1.9	-1.0
Medication: Paracetamol	1.9	2.9	7.4	2.0	1.3	1.8	1.8	1.9	1.8	-0.5	-0.0	2.1	2.7	1.9	1.1	1.1
Ever had prostate specific antigen (PSA) test	1.9	2.2	5.8	1.1	1.2	1.9	1.6	1.2	1.2	2.4	2.4	0.8	0.3	0.8	2.1	-0.5
Crohns Disease (2012)	1.8	2.9	5.2	-1.4	-1.6	-2.3	-1.9	-2.0	-2.0	-1.4	-2.0	-0.6	-1.2	-1.9	-2.1	-0.6
Systolic Blood Pressure	1.8	9.1	13.6	-3.0	-2.6	-3.7	-3.4	-3.1	-2.9	-3.5	-3.6	-3.3	-1.7	-2.7	-3.6	-0.2
Asthma	1.8	3.5	7.0	1.3	1.8	2.6	2.1	2.1	2.1	1.6	1.9	1.8	1.1	2.1	2.3	0.5
Comparative height size at age 10	1.8	9.7	31.4	-1.9	-2.2	-3.5	-2.6	-1.3	-1.0	-5.6	-4.6	-3.4	-1.6	-0.7	-3.4	4.2
Eye problems/disorders: Cataract	1.8	2.1	7.0	-2.0	-2.6	-1.1	-1.4	-1.6	-1.9	-0.1	-0.5	-0.6	-0.8	-1.7	-0.6	-1.3
Number of operations (self-reported)	1.8	2.7	5.3	1.6	1.1	1.0	1.9	2.2	2.2	0.2	0.9	1.2	1.5	2.3	1.3	2.3
Rheumatoid Arthritis	1.7	2.4	6.9	-1.6	-0.7	-0.7	-1.6	-1.8	-1.7	0.1	-1.2	-2.6	-1.6	-1.7	-1.3	-1.7
Schizophrenia (2014)	1.7	3.7	10.7	-1.5	-1.1	0.8	-0.6	-1.7	-1.4	3.3	2.3	-1.3	-2.6	-1.9	0.2	-3.3
Relative age voice broke	1.7	2.6	9.6	-0.1	-0.3	1.0	-0.2	-1.2	-0.6	3.1	2.4	-0.7	-2.9	-1.3	-0.6	-2.1
Number of live births	1.7	2.4	10.4	0.0	-0.6	1.7	0.1	-0.7	-0.4	3.1	2.1	0.3	-0.4	-1.1	1.0	-3.2
Pulse wave reflection index	1.7	2.1	4.1	1.6	1.1	1.1	1.7	1.7	1.8	-0.2	0.5	1.4	2.0	1.8	1.0	1.4
Supplements: Calcium	1.7	1.9	7.1	1.5	1.2	1.2	1.6	1.1	1.2	2.2	2.7	-0.4	-1.1	1.0	0.5	-0.2
Fasting Glucose	1.6	1.9	4.7	0.9	1.4	1.2	1.8	1.8	1.4	0.3	0.6	2.2	1.0	1.0	1.8	1.3
Cardiovascular Disease	1.6	5.1	13.0	-2.1	-1.4	-2.7	-2.6	-2.1	-2.6	-3.1	-3.6	-0.1	1.9	-2.2	-1.4	-1.5
Hand grip strength (left)	1.6	4.1	6.5	-2.6	-1.5	-2.0	-2.2	-2.1	-2.3	-1.7	-2.1	-2.5	-2.3	-2.1	-1.6	-0.6
Sensitivity / hurt feelings	1.6	2.8	11.0	0.2	-0.0	2.2	1.3	0.4	0.5	3.3	3.1	0.9	-0.5	0.1	2.1	-1.9
Eye problems/disorders: Diabetes related eye disease	1.6	1.8	3.2	-1.4	-1.8	-1.0	-1.5	-1.5	-1.3	-0.8	-1.5	-1.5	-0.8	-1.4	-1.7	-0.5
Worry too long after embarrassment	1.6	2.6	10.8	-0.8	-0.9	1.5	0.7	-0.5	-0.6	3.3	2.5	0.4	-1.6	-0.7	1.4	-2.7
Back pain experienced in last month	1.6	2.3	5.2	-2.3	-1.5	-1.1	-1.3	-1.7	-2.1	0.1	-0.3	0.1	-2.0	-1.9	-0.2	-2.0
Financial difficulties in last 2 years	1.5	2.0	3.4	-1.8	-1.4	-1.4	-1.3	-1.6	-1.7	-1.3	-1.9	-1.1	-0.7	-1.5	-1.4	-0.6
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.5	8.8	-0.4	0.8	2.3	0.6	-0.4	-0.3	2.9	2.2	1.1	-0.5	-0.7	1.4	-3.0
Medication: Paracetamol	1.5	2.5	5.0	1.7	1.6	2.1	1.8	1.6	1.5	0.4	0.6	2.2	2.2	1.5	1.2	0.3
Number of children fathered	1.5	1.7	3.7	-1.9	-0.5	-1.7	-1.3	-1.5	-1.7	0.3	-0.1	-0.5	-1.9	-1.5	-0.6	-1.2
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	3.6	1.3	0.6	1.3	1.6	1.4	1.2	1.6	1.8	1.4	0.8	1.2	1.9	0.2
Long-standing illness, disability or infirmity	1.5	2.3	5.1	1.1	1.0	2.3	1.9	1.5	1.5	1.3	1.4	2.0	1.7	1.4	1.5	-0.1
Bipolar Disorder or Schizophrenia	1.4	3.4	8.0	-1.6	-1.6	-0.3	-1.0	-1.9	-1.6	2.2	1.2	-2.5	-2.7	-1.9	-1.1	-2.8
Intelligence (Savage-Jansen 2018)	1.4	4.2	15.4	-0.2	-1.1	-1.7	-0.9	0.3	0.5	-3.7	-3.0	-2.6	0.1	0.8	-2.0	3.9
Blood White Count	1.4	10.1	39.8	2.5	2.2	-0.0	1.8	3.0	2.4	-3.3	-2.1	4.7	6.3	3.1	1.2	3.6
Supplements: Glucosamine	1.4	1.8	4.5	1.1	0.3	1.7	1.5	1.2	1.2	2.1	2.1	1.1	0.2	1.1	1.6	0.0
Sitting height	1.4	9.7	16.3	-4.0	-2.5	-2.4	-3.9	-3.7	-3.4	-2.6	-3.7	-2.9	-2.9	-3.5	-2.8	-0.3
Alcohol usually taken with meals	1.4	2.3	15.6	0.9	1.1	0.1	0.6	1.3	1.4	-1.9	-0.8	1.0	0.9	1.6	-0.0	3.9
Father’s age at death	1.4	1.9	4.8	1.9	1.0	2.2	1.4	1.0	1.6	1.3	1.5	0.9	1.3	1.0	1.3	-0.2
Length of working week for main job	1.4	1.5	3.0	1.2	1.2	1.0	1.5	1.4	1.3	0.3	1.1	1.7	0.0	1.2	1.6	1.5
Loud music exposure frequency	1.4	1.5	3.6	0.7	1.1	1.5	1.0	0.7	0.6	1.8	1.5	1.8	0.7	0.4	1.9	-0.5
Depressed Affect (Nagel 2018)	1.3	2.7	13.3	-0.2	-0.2	1.2	0.3	-0.8	-0.8	3.0	2.2	0.8	-0.3	-1.1	1.6	-3.6
Irritable Bowel Disease (IBD)	1.3	3.2	6.6	-1.8	-2.6	-1.8	-1.8	-2.1	-2.0	-1.2	-1.5	-1.3	-2.3	-1.9	-1.3	-0.4
Verbal and Numeric Reasoning (VNR)	1.3	3.1	10.9	-0.7	-1.4	-1.9	-1.1	0.1	-0.2	-3.3	-2.7	-1.6	-0.4	0.5	-1.1	3.2
Diabetes (father)	1.3	1.6	4.6	0.0	1.2	1.7	0.1	0.1	0.1	2.1	1.9	0.7	-0.1	-0.2	2.1	-1.8
Exposure to tobacco smoke at home	1.3	1.5	4.8	-1.0	-0.7	-0.8	-1.2	-1.6	-1.7	0.8	0.1	-0.4	-1.1	-1.8	-0.5	-2.2
Birth weight	1.3	2.8	5.4	-1.3	-1.3	-2.3	-1.9	-1.6	-1.5	-2.0	-2.1	-1.6	-1.2	-1.4	-2.0	0.3
Forced vital capacity (FVC), Best measure	1.3	4.7	10.0	-2.6	-1.9	-1.5	-1.9	-2.3	-2.4	-0.8	-1.6	-3.2	-3.1	-2.3	-2.0	-1.3
Pulse rate, automated reading	1.3	4.2	9.5	-2.0	-2.3	-2.9	-1.8	-1.7	-2.4	-2.7	-3.1	-0.5	0.2	-1.7	-1.9	-0.7
Waist Hip Ratio (WHR)	1.2	5.5	21.8	0.6	0.6	-2.5	-1.0	-0.1	0.0	-4.7	-4.2	-0.6	3.0	0.4	-3.1	2.3
Relative age of first facial hair	1.2	2.4	10.3	-1.5	-0.8	0.2	-0.9	-1.6	-1.0	1.8	1.4	-1.8	-3.2	-1.5	-1.0	-1.3
Ever used hormone-replacement therapy (HRT)	1.2	1.5	4.0	0.5	0.2	1.5	1.5	0.9	0.6	1.9	2.0	1.2	0.4	0.7	1.4	-1.5
Pack years adult smoking proportion	1.2	1.8	5.4	-2.3	-1.4	-1.9	-1.3	-1.0	-1.9	-1.0	-1.2	-0.0	-0.8	-1.1	-0.5	-1.1
Hearing difficulty/problems with background noise	1.2	1.9	5.5	0.6	0.6	2.0	1.0	0.8	0.6	2.3	2.4	1.2	0.2	0.5	1.9	-1.1
Fluid intelligence score	1.2	2.5	15.3	0.3	-0.1	-0.9	-0.1	1.1	1.1	-2.6	-1.9	-1.2	0.1	1.5	-0.3	3.9
Medication: Cholesterol lowering	1.2	1.8	4.8	-1.3	-0.2	-1.3	-1.7	-1.2	-1.3	-1.7	-2.2	0.2	1.9	-1.2	-1.0	-0.6
Prospective memory result	1.2	1.5	3.7	1.9	1.0	1.4	1.5	1.3	1.7	1.0	1.3	0.2	1.1	1.3	0.0	0.3
Birth weight of first child	1.2	2.2	10.0	-0.9	-0.9	-1.8	-1.2	-0.9	-1.0	-0.4	-0.1	-2.5	-3.2	-0.7	-1.9	0.2
Had major operations	1.2	1.4	3.8	1.0	1.1	0.2	1.2	1.6	1.4	-0.5	0.0	1.2	1.3	1.6	0.3	2.0
Miserableness	1.2	2.0	13.0	-0.2	-0.6	0.6	-0.2	-1.2	-1.3	2.0	1.5	0.4	-0.2	-1.5	0.6	-3.6
Reaction Time	1.1	2.2	8.1	1.0	0.5	2.3	1.5	0.4	0.6	2.9	2.5	0.6	-0.5	0.3	1.0	-1.7
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	3.3	0.2	1.0	1.6	1.1	0.9	1.0	1.5	1.5	0.7	0.0	0.8	1.8	-0.1
Hair/balding pattern: Pattern 3	1.1	1.6	3.0	1.7	0.5	1.2	1.6	1.7	1.5	1.4	1.7	0.2	0.9	1.6	0.6	-0.1
Headache pain in last month	1.1	2.0	6.2	-0.4	1.2	0.4	0.4	-0.0	-0.5	2.5	2.4	0.2	-2.2	-0.3	0.5	-2.4
Health satisfaction	1.1	1.5	3.6	0.0	0.3	1.6	1.4	0.6	0.2	1.9	1.4	1.8	0.7	0.3	1.4	-1.5
Loneliness, isolation	1.1	1.5	6.8	-0.7	0.4	1.5	0.4	-0.5	-0.4	2.3	1.7	0.2	-0.7	-0.5	0.6	-2.6
Average weekly champagne plus white wine intake	1.1	1.5	8.2	0.7	1.5	0.3	0.7	1.1	1.4	-1.4	-0.7	0.1	1.0	1.4	0.3	2.9
Irritability	1.1	1.8	7.4	-1.2	-1.3	-0.3	-0.8	-1.6	-1.6	1.3	0.2	-1.0	-1.3	-1.7	-0.8	-2.7
HDL Cholesterol	1.0	1.7	3.6	-1.3	-1.5	-1.6	-0.9	-0.7	-0.9	-1.1	-1.0	-1.9	-1.9	-0.5	-1.7	0.8
Respiratory disease	1.0	2.1	3.6	0.9	1.4	1.8	1.9	1.8	1.6	0.8	1.0	1.6	1.3	1.8	1.6	0.6
Taking other prescription medications	1.0	1.6	3.0	0.8	1.5	1.5	1.4	1.3	1.4	0.4	1.0	1.7	0.9	1.3	1.5	1.0
Pulse wave Arterial Stiffness index	1.0	1.1	4.2	0.4	-1.2	0.1	0.3	-0.1	0.4	-1.9	-1.5	0.6	2.1	0.2	-0.9	1.3
Impedance of arm (left)	1.0	4.6	24.6	0.4	-0.9	-1.8	0.5	0.8	1.1	-3.1	-1.5	-2.5	-1.9	1.6	-2.1	5.0
Number of full brothers	1.0	1.3	3.9	-0.6	-1.7	-0.8	-1.0	-1.4	-1.0	0.0	-0.4	-2.0	-1.1	-1.3	-0.8	-0.8
Shortness of breath walking on level ground	1.0	1.2	3.1	0.8	-0.4	1.3	1.2	1.3	1.2	-0.0	0.4	1.7	1.2	1.2	1.4	1.1
Medication for pain relief, constipation, heartburn	1.0	1.7	6.5	-1.0	-1.1	-0.5	-1.1	-1.5	-1.0	1.0	0.6	-1.9	-2.6	-1.5	-0.4	-0.9
Medication: Allopurinol	1.0	1.3	2.7	0.7	0.8	1.4	1.5	1.4	1.3	0.9	1.3	0.5	0.5	1.4	1.6	0.6
Chest pain or discomfort	1.0	1.4	4.2	-0.2	1.0	1.2	0.7	0.6	0.1	1.5	1.3	2.0	1.5	0.2	1.7	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	1.7	-0.9	-1.3	-0.9	-1.1	-1.0	-1.1	-1.0	-1.3	-1.3	-0.7	-1.0	-1.1	-0.6
Osteoporosis (self-reported)	1.0	1.2	2.8	0.7	1.5	1.4	1.1	0.7	0.7	1.7	1.6	1.0	-0.1	0.5	1.2	-0.6
Cholesterol lowering medication	1.0	1.4	3.2	-1.4	-0.7	-1.0	-1.8	-1.5	-1.4	-1.1	-1.4	0.3	0.6	-1.5	-0.7	-1.0
Body Mass Index (BMI) (2010)	0.9	1.3	3.8	1.0	0.2	1.4	0.4	0.6	0.5	1.5	1.2	1.5	1.9	0.3	1.1	-1.3
Triglycerides	0.9	1.4	7.7	-0.2	0.3	0.5	-1.9	-0.7	-0.9	1.4	0.6	1.3	0.5	-1.0	0.4	-2.8
Blood Red Count	0.9	8.8	16.8	3.1	3.2	2.6	3.0	3.2	3.1	1.1	2.0	4.1	3.4	2.9	3.6	2.0
Impedance of arm (right)	0.9	4.3	23.6	0.8	-0.7	-1.6	0.6	0.9	1.2	-2.7	-1.1	-2.3	-2.2	1.6	-2.0	4.9
Noisy workplace	0.9	1.1	3.7	-1.5	-1.0	-0.8	-1.0	-0.9	-1.3	0.4	-0.7	0.9	0.9	-1.1	0.2	-1.9
Breastfed as a baby	0.9	1.1	3.3	-0.1	-0.5	0.4	-1.4	-1.4	-0.9	0.1	-1.0	-0.7	1.2	-1.6	-0.8	-1.8
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	3.0	1.7	0.9	1.3	1.5	1.3	1.7	0.2	0.9	-0.9	0.4	1.4	0.0	1.7
Pulse wave peak to peak time	0.9	1.1	5.5	-0.7	1.0	-0.4	-0.4	0.0	-0.5	1.6	1.3	-0.9	-2.3	-0.3	0.7	-1.0
Angina (self-reported)	0.9	1.2	4.0	-0.0	0.7	1.4	0.8	0.6	0.4	2.0	1.5	1.2	0.3	0.2	1.0	-1.6
Mood swings	0.9	1.6	7.7	-1.1	-1.2	-0.5	-0.6	-1.4	-1.7	1.2	0.7	0.1	-0.6	-1.5	0.3	-2.8
Medication: Lisinopril	0.9	1.2	3.1	-1.4	-0.4	-1.8	-1.4	-0.6	-0.9	-1.8	-1.4	0.0	0.2	-0.5	-0.7	0.9
Smoking Status	0.8	1.8	4.2	1.6	0.3	0.2	1.6	1.5	1.1	-1.1	-0.1	1.5	2.0	1.5	0.6	2.0
Number of treatments/medications taken	0.8	1.4	4.0	0.9	1.0	0.8	1.0	1.3	1.1	-0.8	-0.2	1.8	2.0	1.3	1.0	1.1
Serious illness, injury or assault to yourself	0.8	0.9	3.9	-0.5	-0.4	-1.1	-0.7	0.0	-0.2	-2.0	-1.5	-0.6	-0.0	0.1	-1.6	0.8
Heart attack	0.8	1.1	2.5	-1.1	-0.4	-1.1	-1.0	-0.7	-1.0	-1.2	-1.6	0.5	1.6	-0.9	-0.8	-0.6
Trunk fat-free mass	0.8	4.3	9.3	-2.7	-1.5	-1.6	-3.1	-2.6	-2.4	-2.1	-2.7	-0.6	-0.7	-2.6	-1.6	-0.6
Medication: Amlodipine	0.8	1.1	6.0	-0.5	0.4	0.4	-0.6	-1.1	-1.0	1.5	0.5	-0.5	-0.3	-1.4	0.1	-2.5
Arm predicted mass (right)	0.8	4.1	8.8	-2.8	-1.6	-1.5	-3.0	-2.5	-2.6	-1.4	-2.4	-0.1	-0.5	-2.7	-1.2	-1.6
Leg pain on walking	0.8	1.1	6.7	-0.6	-1.1	0.2	-0.5	-0.8	-1.0	1.3	0.6	0.1	-0.6	-1.0	0.3	-2.6
Financial situation satisfaction	0.8	1.0	2.8	-1.4	-0.6	0.7	-0.3	-1.1	-1.1	1.1	0.5	0.0	-0.9	-1.3	0.8	-1.7
Ever smoked	0.8	1.4	8.1	1.0	0.9	0.7	0.7	0.4	1.0	-1.5	-1.0	0.5	2.9	0.6	-0.3	1.5
Basal metabolic rate	0.8	4.3	9.3	-2.7	-1.5	-1.6	-3.0	-2.5	-2.6	-1.9	-2.7	-0.2	-0.3	-2.6	-1.4	-1.2
Age started oral contraceptive pill	0.8	1.0	6.7	0.3	0.2	-0.2	0.1	0.7	0.9	-1.2	-0.5	-1.0	-0.6	1.1	-0.8	2.6
Ever depressed for a whole week	0.8	1.0	2.4	0.9	0.2	1.0	1.3	1.3	1.3	-0.2	0.0	0.2	1.5	1.3	0.4	1.2
Heart attack/myocardial infarction (self-reported)	0.8	1.0	3.6	-0.9	-0.3	-1.0	-0.9	-0.5	-0.8	-1.3	-1.6	0.5	1.9	-0.6	-0.8	-0.4
Heart disease (siblings)	0.8	0.9	3.6	0.9	0.0	0.2	0.7	1.1	1.1	-0.3	0.3	1.5	1.9	1.0	1.1	0.8
Impedance of whole body	0.8	3.8	20.1	0.4	-1.0	-1.9	0.4	0.7	0.9	-2.7	-1.3	-2.3	-2.0	1.4	-1.9	4.5
LDL Cholesterol	0.7	1.1	7.6	-0.0	-0.5	0.7	-0.9	-0.7	-0.5	1.7	1.1	0.4	0.1	-0.8	0.1	-2.7
Blood Platelet Count	0.7	7.7	31.1	0.3	0.4	-2.3	-0.4	0.6	0.2	-5.2	-5.1	1.0	5.6	1.1	-1.7	2.0
Hearing difficulty/problems: Yes	0.7	1.0	3.4	1.1	0.4	0.6	0.5	1.0	1.1	-0.5	0.2	1.4	1.1	1.2	0.8	1.8
Leg fat-free mass (left)	0.7	3.5	7.2	-2.4	-1.2	-1.3	-2.7	-2.3	-2.3	-1.6	-2.4	-0.2	-0.3	-2.4	-1.3	-1.3
Multivitamins +/- minerals	0.7	0.9	2.1	0.9	0.6	0.6	1.4	1.1	0.7	1.3	1.5	0.9	-0.1	1.0	1.1	0.1
Chronic bronchitis/emphysema (father)	0.7	0.9	2.9	0.5	0.1	-0.7	-0.7	0.4	0.4	-1.7	-1.3	1.2	1.4	0.4	-0.1	1.2
Leg predicted mass (left)	0.7	3.6	7.3	-2.5	-1.3	-1.3	-2.7	-2.3	-2.4	-1.6	-2.4	-0.3	-0.4	-2.5	-1.3	-1.4
Qualifications: None of the above	0.7	1.5	3.8	-1.4	-1.1	-1.6	-1.2	-1.4	-1.6	0.2	-0.3	0.6	-0.7	-1.4	-0.7	-1.9
Falls in the last year	0.7	0.9	4.0	-0.4	1.0	0.1	0.3	0.7	0.3	-1.3	-1.0	1.5	2.0	0.6	0.8	0.1
Pulse rate	0.7	1.3	2.8	-1.2	-1.3	-1.0	-1.1	-1.3	-1.4	-1.4	-1.7	-0.5	-0.3	-1.3	-0.8	0.1
Trunk predicted mass	0.7	4.3	9.2	-2.7	-1.5	-1.6	-3.0	-2.6	-2.4	-2.0	-2.7	-0.6	-0.7	-2.6	-1.6	-0.6
High blood pressure (siblings)	0.7	0.9	1.7	-0.9	-1.3	-1.2	-1.2	-1.2	-1.1	-0.4	-0.8	0.0	-0.6	-1.2	-0.9	-1.0
Arm fat-free mass (right)	0.7	3.8	7.9	-2.6	-1.5	-1.4	-2.8	-2.5	-2.5	-1.4	-2.4	-0.0	-0.3	-2.6	-1.0	-1.6
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.3	0.6	0.9	1.5	0.4	-0.0	0.5	1.5	1.4	0.1	-1.3	-0.1	0.7	-0.2
Smoking status: Previous	0.7	1.1	4.1	1.2	0.6	1.6	1.0	0.7	1.3	-0.3	-0.1	0.3	2.0	0.8	0.8	1.2
Whole body fat-free mass	0.7	4.2	8.9	-2.7	-1.5	-1.5	-3.0	-2.6	-2.5	-1.8	-2.6	-0.4	-0.6	-2.7	-1.4	-1.1
Leg fat-free mass (right)	0.7	3.6	7.3	-2.6	-1.5	-1.3	-2.7	-2.4	-2.4	-1.6	-2.4	-0.2	-0.4	-2.5	-1.3	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	3.5	-0.4	0.1	1.2	-0.0	0.1	-0.1	1.9	1.5	1.3	-0.4	-0.2	1.5	-1.5
Whole body water mass	0.7	4.1	8.7	-2.7	-1.6	-1.5	-2.9	-2.6	-2.5	-1.7	-2.5	-0.5	-0.7	-2.7	-1.4	-1.1
Leg predicted mass (right)	0.7	3.7	7.4	-2.6	-1.5	-1.3	-2.7	-2.4	-2.4	-1.6	-2.4	-0.2	-0.4	-2.5	-1.3	-1.3
Alcohol drinker status: Never	0.7	0.8	2.0	-1.4	-0.8	-0.7	-0.6	-0.8	-1.2	-0.4	-0.5	-0.7	-0.8	-0.9	-1.0	-1.3
Risk taking	0.7	1.1	3.3	1.4	-0.2	-0.4	0.4	1.0	0.8	-1.6	-1.1	0.6	1.8	1.1	-0.6	1.2
Pain experienced in last month	0.7	1.2	4.1	0.2	-0.7	-1.1	-0.8	-0.0	0.2	-1.5	-1.1	-2.0	-0.3	0.1	-1.2	1.9
Basal cell carcinoma (self-reported)	0.7	0.9	2.2	-1.2	-0.9	-0.4	-0.9	-1.4	-1.2	0.3	-0.2	-0.5	-0.7	-1.5	-0.0	-1.1
Pack years of smoking	0.7	1.0	3.6	-1.9	-1.3	-1.5	-0.9	-0.5	-1.4	-0.7	-0.8	0.4	-0.5	-0.6	0.0	-0.7
Arm predicted mass (left)	0.7	3.5	7.6	-2.4	-1.5	-1.4	-2.8	-2.5	-2.5	-1.1	-2.0	0.2	-0.5	-2.6	-0.9	-1.7
Ulcerative Colitis (UC)	0.6	1.1	3.1	-1.3	-1.8	-0.5	-1.1	-1.4	-1.1	-0.2	-0.6	-0.8	-1.5	-1.3	-0.1	-0.3
Ovarian Cancer	0.6	0.8	2.5	1.0	0.6	0.8	0.6	0.8	1.0	-1.0	-0.4	0.6	0.8	1.0	-0.1	1.6
Coronary Artery Disease (CAD)	0.6	0.7	2.4	-1.0	-1.0	-0.8	-0.9	-0.8	-1.1	-0.0	-0.5	-0.5	0.2	-1.0	-0.2	-1.6
Primary Biliary Cirrhosis	0.6	0.9	2.0	1.4	0.2	-0.1	1.0	1.0	1.0	-0.1	0.6	1.1	1.4	1.0	0.9	0.9
Hair Pigment	0.6	17.3	33.8	3.7	3.5	4.7	4.6	4.7	4.4	4.2	5.2	3.5	1.6	4.2	5.8	1.7
Angina	0.6	0.8	2.8	-0.1	0.5	1.1	0.6	0.5	0.3	1.7	1.2	1.1	0.4	0.1	0.7	-1.5
Body mass index (BMI)	0.6	2.4	10.2	-0.4	0.5	0.2	-0.8	-0.3	-1.0	1.0	0.1	3.1	2.3	-0.9	1.4	-3.2
Trunk fat mass	0.6	2.4	5.4	-1.6	-1.3	-2.3	-2.1	-1.2	-1.7	-1.9	-2.1	1.2	0.5	-1.3	-0.9	-0.5
Waist circumference	0.6	2.1	8.8	-0.2	0.2	-1.2	-1.5	-0.5	-0.9	-1.7	-2.1	2.2	3.0	-0.7	-0.3	-0.8
Past tobacco smoking	0.6	1.1	6.1	-1.0	-0.5	-1.1	-0.8	-0.5	-1.0	1.0	0.7	-0.4	-2.5	-0.6	-0.3	-1.2
Weight	0.6	3.2	7.6	-2.2	-1.2	-1.8	-2.8	-1.9	-2.1	-1.7	-2.4	0.7	0.3	-2.1	-0.9	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	2.6	0.5	1.6	0.8	0.3	0.3	0.5	1.0	1.4	-0.2	0.8	0.2	0.5	-0.7
Hair/balding pattern: Pattern 4	0.6	1.4	3.3	1.1	1.3	1.5	0.4	0.1	0.3	1.8	1.5	1.2	1.0	-0.3	1.7	-1.4
Peak expiratory flow (PEF)	0.6	1.5	4.9	-1.1	-0.4	-1.2	-1.2	-1.0	-0.9	-1.2	-1.0	-2.2	-1.5	-1.0	-1.7	0.2
Medication for cholesterol, blood pressure or diabetes	0.6	1.1	2.6	1.0	0.2	0.8	1.4	1.1	1.1	1.0	1.6	-0.0	-1.4	1.1	0.5	0.8
Exposure to tobacco smoke outside home	0.6	0.8	3.3	-0.7	-0.5	-1.0	-0.9	-0.9	-1.3	-0.2	-0.5	0.6	0.5	-1.2	0.2	-1.8
Family relationship satisfaction	0.6	0.7	2.0	0.8	1.0	1.1	1.4	0.9	0.9	0.7	0.6	-0.0	0.6	0.9	0.5	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	2.6	-1.6	-0.8	-1.2	-1.0	-1.0	-1.4	-0.7	-0.9	-1.5	-1.1	-1.1	-0.7	-0.4
Number of self-reported non-cancer illnesses	0.6	1.0	1.6	0.8	1.1	0.7	1.2	1.1	1.3	0.2	0.9	1.2	1.0	1.1	1.0	0.9
Medication: Blood pressure	0.6	1.1	4.9	0.2	0.1	-1.0	-0.5	-0.0	0.1	-2.2	-1.7	1.0	1.5	0.2	-0.5	1.5
Arm fat-free mass (left)	0.6	3.3	7.0	-2.4	-1.6	-1.3	-2.6	-2.3	-2.4	-0.9	-1.9	0.0	-0.7	-2.5	-0.9	-1.7
Unable to work because of sickness or disability	0.6	0.8	1.5	-1.2	-0.7	-0.9	-0.6	-0.6	-1.0	-0.9	-0.9	-1.1	-1.2	-0.5	-0.9	-0.6
Bipolar Disorder (2018)	0.5	0.8	2.9	-0.5	-0.2	-1.3	-0.7	-0.8	-0.6	-0.8	-0.8	-1.7	-0.5	-0.6	-1.5	0.1
Breast Cancer	0.5	1.3	4.3	1.3	2.0	0.5	0.5	1.1	0.8	-0.7	-0.5	0.6	2.1	1.2	1.0	1.0
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.5	0.5	0.6	1.2	0.8	0.4	0.5	1.0	0.8	1.2	0.8	0.5	0.9	-0.1
BMI	0.5	3.1	15.4	0.0	0.4	-0.5	-1.0	-0.1	-0.7	-0.6	-1.4	3.7	3.9	-0.6	1.0	-2.2
Chronotype (morning person)	0.5	1.1	2.6	-1.2	-0.2	-1.0	-1.4	-1.4	-1.3	-0.2	-0.9	-0.5	-0.6	-1.6	-0.3	-1.2
Tanning	0.5	6.7	10.8	-2.9	-2.4	-2.8	-2.8	-2.7	-2.8	-1.4	-2.7	-3.3	-2.6	-2.5	-2.8	-1.3
Impedance of leg (right)	0.5	2.5	11.4	0.3	-0.9	-1.9	0.0	0.4	0.5	-2.4	-1.4	-1.7	-1.3	0.9	-1.7	3.4
Townsend deprivation index at recruitment	0.5	0.7	1.9	0.2	1.0	-0.2	0.6	0.9	0.8	-0.2	0.6	-1.4	-1.1	1.1	-0.3	1.2
Average weekly fortified wine intake	0.5	0.6	2.8	0.0	0.1	-0.2	0.7	1.0	0.9	-0.4	0.2	-1.1	-0.3	1.1	0.5	1.7
High blood pressure	0.5	1.5	5.3	-0.6	0.1	-1.9	-1.3	-0.4	-0.8	-2.3	-2.1	0.9	1.5	-0.4	-0.4	0.6
Impedance of leg (left)	0.5	2.6	11.4	-0.0	-1.4	-2.1	-0.1	0.1	0.3	-2.4	-1.4	-1.5	-1.6	0.7	-1.7	3.4
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.0	4.4	-0.1	0.3	-0.8	0.2	0.4	0.1	-2.1	-1.7	0.2	1.5	0.6	-0.7	1.4
Lung cancer (father)	0.5	0.5	1.7	-0.1	-1.0	-0.8	-0.3	-0.3	-0.4	-1.3	-1.3	0.6	0.3	-0.1	-0.9	0.5
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.6	-0.7	-1.6	0.4	0.1	-0.4	-0.3	1.1	0.7	-0.4	-0.8	-0.3	0.2	-1.4
Comparative body size at age 10	0.5	1.3	4.1	-0.9	-1.2	-1.4	-0.3	0.3	-0.4	-2.0	-2.0	-1.1	1.1	0.4	-0.5	1.0
Wheeze or whistling in the chest in last year	0.5	0.9	4.7	0.0	0.2	0.8	0.7	0.8	0.3	0.5	0.7	2.2	0.9	0.7	1.7	-0.2
Qualifications: College or University degree	0.5	1.7	4.2	0.9	0.9	1.7	1.7	1.8	1.6	0.2	1.0	-0.2	0.3	1.8	0.8	2.0
Eye problems/disorders: None of the above	0.5	0.6	1.7	-0.2	0.3	-1.3	-1.0	-0.7	-0.6	-0.6	-0.4	-0.3	-1.2	-0.5	-1.1	0.2
Medication: Seretide 50 evohaler	0.5	0.6	1.8	-0.2	0.4	0.2	0.5	0.6	0.4	-1.2	-0.9	0.9	1.2	0.7	0.4	1.3
Whole body fat mass	0.5	1.9	3.5	-1.3	-1.1	-1.7	-1.9	-1.1	-1.6	-1.2	-1.7	1.6	1.0	-1.3	-0.4	-1.2
Leg fat mass (right)	0.5	1.8	4.1	-1.1	-0.5	-1.2	-1.7	-1.0	-1.5	-0.6	-1.3	1.9	1.6	-1.3	0.1	-2.0
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.8	0.7	1.1	1.3	0.3	0.2	0.6	1.3	1.1	-0.4	0.8	0.1	0.6	-0.6
Supplements: Vitamin C	0.5	0.6	1.9	-0.2	0.8	0.6	0.6	0.3	0.1	1.1	1.3	0.4	-0.8	0.3	1.4	-0.2
Illnesses of father: Heart disease	0.5	0.8	4.1	-0.9	0.6	0.3	-0.6	-0.6	-0.6	0.8	-0.1	0.4	1.3	-0.8	0.4	-2.0
Commuting to job workplace: Walk	0.5	0.5	2.5	-0.3	-0.8	-0.8	-0.3	0.0	-0.2	-1.6	-0.9	-0.3	-0.3	0.2	-0.6	1.1
Hearing aid user	0.5	0.6	2.4	0.1	-1.1	-0.7	-0.2	0.2	0.1	-0.9	-1.0	-1.5	0.2	0.4	-1.4	0.2
Myopia	0.5	0.7	1.7	-0.4	-0.6	-0.1	-0.7	-1.2	-0.7	0.9	0.3	-1.3	-1.0	-1.1	-0.6	-0.9
Vascular/heart problems diagnosed by doctor	0.5	1.4	3.9	0.6	-0.0	1.6	1.3	0.6	0.9	1.9	2.0	-1.2	-1.7	0.6	0.3	0.1
Alcohol drinker status: Previous	0.5	0.6	2.0	1.4	-0.5	0.5	0.7	0.8	0.6	0.7	1.0	0.9	0.2	0.7	0.7	-0.2
Leg fat mass (left)	0.5	1.9	5.1	-1.2	-0.7	-1.3	-1.8	-1.1	-1.6	-0.4	-1.1	1.9	1.3	-1.4	0.1	-2.2
Blood Eosinophil Count	0.4	2.8	6.6	1.1	1.7	1.7	1.2	1.8	1.6	0.9	1.2	2.6	2.5	1.5	2.4	0.2
Average weekly spirits intake	0.4	0.4	1.6	-0.1	0.2	-0.3	-0.1	-0.2	-0.5	0.7	0.7	1.3	0.8	-0.4	0.8	-1.1
Vitamin and mineral supplements	0.4	0.6	1.7	-0.2	0.1	-0.5	-0.8	-0.5	-0.1	-1.2	-1.3	-0.3	1.3	-0.4	-1.1	0.1
Supplements: Zinc	0.4	0.4	1.8	-0.3	-0.7	-1.3	-0.6	-0.6	-0.9	-0.2	-0.1	-0.7	-0.3	-0.6	-0.7	-0.5
Current tobacco smoking	0.4	0.6	4.2	0.6	0.4	-0.7	0.6	0.7	0.1	-0.6	0.1	2.1	1.1	0.7	0.2	0.5
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.7	0.4	-0.4	-1.3	-0.0	0.4	0.3	-0.8	-0.6	1.1	0.8	0.6	-0.4	0.9
Medication: Levothyroxine sodium	0.4	0.7	2.2	0.6	1.5	1.1	0.8	0.7	1.1	0.1	0.5	-0.1	0.4	0.9	-0.2	1.0
Pain all over the body in last month	0.4	0.4	3.4	0.7	0.4	0.2	0.5	0.1	0.3	-0.0	0.3	1.0	1.8	0.1	0.4	-0.3
Illnesses of siblings	0.4	0.6	2.1	0.4	1.4	0.8	0.9	0.8	0.7	-0.2	0.2	-0.5	0.1	0.9	0.2	1.4
Hip circumference	0.4	1.6	4.0	-1.3	-0.4	-1.0	-2.0	-1.1	-1.5	-0.9	-1.4	1.7	1.3	-1.4	0.1	-1.4
Depression (self-reported)	0.4	0.5	1.3	-0.6	-0.3	-0.7	-0.8	-1.1	-0.7	-0.2	0.0	-0.4	-0.1	-1.1	-1.0	-0.4
Illnesses of mother	0.4	0.5	1.9	0.5	0.1	0.5	0.9	0.6	0.5	1.4	1.2	-0.0	-0.8	0.5	0.3	-0.1
Leg fat percentage (right)	0.4	1.5	8.1	0.1	0.3	-0.7	-0.5	0.3	-0.3	-0.2	-0.6	2.8	2.6	-0.0	1.0	-1.4
Migraine (self-reported)	0.4	0.5	1.7	-0.4	0.1	-1.2	-0.7	-0.5	-0.3	-1.2	-0.6	-0.4	-0.6	-0.4	-1.3	0.5
Medication: Ibuprofen	0.4	0.4	2.9	0.3	0.7	-0.1	0.4	0.5	-0.0	-0.4	-0.8	0.7	1.7	0.4	0.1	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	1.7	-0.3	0.2	1.1	0.2	-0.0	-0.3	1.3	0.5	-0.3	0.1	-0.2	1.2	-0.9
Age at last live birth	0.4	0.6	1.3	1.1	0.8	1.0	0.7	0.9	0.8	0.4	0.7	0.0	-0.8	0.8	0.2	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.3	-0.2	-0.6	-0.3	-0.8	-1.0	-0.9	-0.1	-0.8	0.2	0.8	-1.0	0.0	-1.2
Medication: Aspirin	0.4	0.6	2.1	-0.4	-0.1	-0.8	-0.1	0.6	-0.2	-1.4	-1.1	0.8	1.3	0.5	0.1	0.3
Knee pain experienced in last month	0.4	0.6	2.2	-0.7	-0.6	-0.5	-0.4	-0.4	-0.8	0.7	0.4	1.4	-0.8	-0.4	0.6	-1.5
Hypertension (Self-reported)	0.4	1.0	3.5	-0.1	0.4	-1.1	-0.5	0.1	-0.2	-1.9	-1.5	1.4	1.8	0.1	0.3	0.8
Illnesses of siblings: Diabetes	0.4	0.5	2.9	0.2	-0.6	0.1	-0.1	0.0	0.0	0.3	-0.2	1.7	1.7	-0.1	0.7	-0.5
Handedness (chirality/laterality): Left-handed	0.4	0.4	2.4	0.5	-0.3	-0.5	0.3	0.6	0.6	-0.7	-0.0	-0.4	-0.8	0.7	-0.0	1.5
Mineral and other dietary supplements	0.4	0.6	2.6	0.3	0.7	-0.1	-0.5	-0.1	0.1	-1.4	-1.4	0.5	1.6	-0.0	-0.2	0.4
Medication: Aspirin	0.4	0.5	1.8	-0.6	-0.2	-0.8	-0.1	0.5	-0.3	-1.4	-1.1	0.6	1.2	0.4	0.1	0.2
Medication: Gliclazide	0.4	0.5	1.8	-0.3	-0.3	0.6	0.7	0.8	0.5	0.7	0.7	1.0	0.3	0.7	1.4	0.4
Smoking status: Current	0.4	0.7	3.5	0.7	0.5	-0.5	0.8	0.9	0.4	-0.5	0.1	1.9	1.1	0.8	0.4	0.9
Guilty feelings	0.4	0.6	2.0	-1.0	-0.8	-0.4	0.0	-0.8	-0.8	1.1	0.6	-0.2	-0.9	-0.7	0.1	-1.4
Ever taken oral contraceptive pill	0.4	0.5	1.0	-0.1	-0.2	-0.8	-0.8	-0.8	-0.7	-0.8	-1.0	0.3	1.0	-0.7	-0.3	-0.4
Tinnitus: Yes, now most or all of the time	0.4	0.5	2.3	-0.5	-1.1	0.1	-0.2	-0.3	-0.3	0.9	1.0	0.1	-1.5	-0.3	0.4	-0.3
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.2	-0.0	-0.4	0.3	0.3	-0.1	-0.1	1.5	1.5	-0.2	-1.4	-0.2	0.3	-0.5
Leg fat percentage (left)	0.4	1.5	8.9	-0.2	-0.1	-0.8	-0.6	0.1	-0.5	-0.0	-0.3	3.0	2.4	-0.2	0.9	-1.7
Prostate Cancer	0.3	0.5	2.8	0.3	0.4	-0.9	0.2	0.6	0.2	-0.7	-0.4	0.7	1.7	0.7	-0.3	0.6
Age at First Birth	0.3	0.4	1.2	0.5	0.7	0.7	0.7	0.6	0.7	-0.3	0.4	-0.2	-0.9	0.6	0.5	1.1
Lupus	0.3	0.5	1.3	-0.5	-0.8	-0.4	-0.5	-0.7	-0.8	0.6	0.3	-0.5	-1.1	-0.8	-0.4	-1.0
Hypothyroidism (self reported)	0.3	0.6	1.7	-1.0	-0.3	0.2	-0.8	-1.0	-0.3	-0.6	-0.9	-1.3	-0.5	-0.8	-0.9	0.3
Lung FEV1/FVC ratio	0.3	1.6	4.2	-0.8	-0.9	-1.7	-1.1	-0.9	-0.8	-2.0	-1.7	-0.4	-1.0	-0.7	-1.3	1.7
Diabetes (mother)	0.3	0.4	1.1	0.0	0.4	-1.0	-0.4	0.1	-0.2	-1.0	-0.9	0.8	0.9	0.0	-0.4	0.2
Severe depression (siblings)	0.3	0.4	1.0	-1.0	-0.8	-0.3	-0.4	-0.6	-0.6	-0.6	-0.5	-0.9	-0.3	-0.7	-0.4	0.5
Trunk fat percentage	0.3	1.1	3.3	-0.7	-0.8	-1.8	-1.1	-0.3	-0.8	-1.3	-1.3	1.8	0.8	-0.4	-0.3	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.4	0.0	0.2	-0.6	0.5	0.5	0.3	-1.6	-1.1	0.2	1.0	0.7	-0.3	1.4
Qualifications: CSEs or equivalent	0.3	0.4	3.3	0.2	0.7	0.4	-0.2	-0.3	-0.4	0.8	0.3	-0.4	0.3	-0.5	0.2	-1.8
Medication: Atenolol	0.3	0.4	1.1	-0.4	0.2	-0.3	-0.8	-0.6	-0.3	-0.8	-1.1	0.6	0.6	-0.6	-0.6	-0.1
Had menopause	0.3	0.4	1.4	0.6	-0.3	0.3	0.6	0.5	0.3	0.9	1.2	1.2	0.4	0.4	0.2	-0.3
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.0	0.1	0.1	0.5	0.8	0.6	0.3	0.4	0.3	0.9	0.7	0.4	1.0	-0.1
Time employed in main current job	0.3	0.4	1.2	-0.6	-0.6	-0.4	-0.2	-0.3	-0.7	0.7	0.4	0.5	-0.7	-0.5	0.5	-1.1
Alcohol intake versus 10 years previously	0.3	0.5	2.0	-0.3	0.3	-1.4	-0.0	0.6	-0.4	-1.1	-0.5	1.0	-0.5	0.6	0.0	0.9
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.4	1.0	-0.0	0.8	1.1	0.8	0.8	-0.2	0.3	-1.2	0.2	0.9	-0.6	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	2.9	-0.2	0.3	0.0	0.2	0.2	-0.2	-0.3	-0.9	0.6	1.7	0.1	0.3	-0.6
Arm fat mass (right)	0.3	1.4	4.1	-1.1	-0.4	-1.2	-1.5	-0.8	-1.4	-0.7	-1.1	2.0	1.0	-1.1	0.1	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.3	-1.1	-0.7	-1.0	-0.3	-0.7	-0.8	-0.4	-0.2	-1.1	-0.6	-0.5	-0.6	-0.2
Gout (self-reported)	0.3	0.4	1.0	0.6	0.8	0.0	0.8	0.8	0.7	-0.5	-0.1	0.4	1.0	0.9	0.2	0.7
Body fat percentage	0.3	1.0	4.9	-0.5	-0.5	-1.3	-1.0	-0.2	-0.8	-0.7	-0.9	2.2	1.3	-0.4	0.2	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	1.0	-0.5	-0.5	-0.6	-0.5	-0.2	-0.1	-1.0	-0.5	-1.0	-0.5	0.0	-0.0	0.8
Age at first live birth	0.3	0.5	1.6	0.0	0.0	-0.5	-0.4	-0.2	-0.4	-1.3	-1.1	-0.9	-0.7	-0.1	-1.0	0.7
Emphysema/chronic bronchitis	0.3	0.4	1.3	-0.3	-0.5	-0.1	0.3	1.0	0.6	-0.6	-0.0	0.1	-0.1	1.1	0.3	1.1
Medication: Omeprazole	0.3	0.3	1.2	-0.3	-0.2	-1.1	-0.7	-0.2	-0.4	-1.0	-0.8	0.7	-0.0	-0.2	-0.4	0.3
Heart disease (mother)	0.3	0.3	1.8	-0.1	0.3	-0.1	-0.3	0.3	0.1	-0.7	-0.5	1.4	1.1	0.3	0.5	0.0
Number of full sisters	0.3	0.4	0.8	-0.1	0.6	0.7	-0.3	-0.8	-0.5	0.7	0.6	0.2	-0.9	-0.8	-0.3	-0.8
Average weekly red wine intake	0.3	0.5	2.4	0.1	-1.2	0.8	0.4	-0.0	0.6	0.0	0.4	-1.6	-0.3	0.2	-0.4	0.9
Arm fat mass (left)	0.3	1.2	3.7	-1.1	-0.5	-1.0	-1.5	-0.7	-1.3	-0.5	-1.0	1.9	1.0	-1.0	0.3	-1.5
Wears glasses or contact lenses	0.3	0.4	1.8	0.4	-0.4	0.1	0.6	0.3	0.4	1.2	1.3	0.4	0.4	0.3	0.0	-0.2
Mother’s age at death	0.3	0.3	1.3	0.7	0.6	0.4	0.5	0.3	0.8	0.1	0.7	0.2	-0.2	0.4	0.4	1.1
Eye problems/disorders: Glaucoma	0.3	0.3	0.7	0.4	0.7	0.4	0.5	0.6	0.8	0.0	0.2	-0.6	-0.0	0.7	0.6	0.8
Heel T-Score	0.2	1.9	7.9	1.1	1.9	0.7	0.8	1.4	1.6	-1.1	-0.6	0.8	2.8	1.5	0.3	1.4
Lung FVC	0.2	1.3	7.0	0.1	-0.3	1.2	0.6	-0.1	-0.2	2.1	1.3	-0.6	0.2	-0.3	0.9	-2.7
Ever had hysterectomy (womb removed)	0.2	0.2	1.1	1.0	-0.1	-0.4	0.5	0.4	0.3	0.5	0.7	0.1	0.2	0.6	-0.6	0.2
Age when periods started (menarche)	0.2	0.6	1.9	-0.6	-0.3	0.3	-0.8	-0.9	-0.7	0.9	0.3	0.6	-1.4	-0.9	0.1	-1.1
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.4	0.6	0.5	-0.3	0.0	0.3	0.5	-0.6	-0.5	0.5	0.2	0.5	-0.6	0.5
Medication: Ramipril	0.2	0.2	0.7	-0.7	-0.5	0.2	-0.1	-0.3	-0.4	-0.6	-0.9	-0.8	0.4	-0.4	0.4	0.0
Arm fat percentage (right)	0.2	0.9	6.8	-0.1	0.2	-0.8	-0.7	0.1	-0.4	-0.1	-0.3	2.6	1.6	-0.2	0.8	-1.0
Happiness	0.2	0.3	0.9	-0.4	-0.2	0.3	0.7	-0.1	-0.4	0.7	0.5	-0.8	-0.8	-0.2	0.0	-1.0
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.9	-0.7	-0.9	-0.4	-0.1	-0.2	-0.2	-0.1	-0.0	-0.5	-0.8	-0.1	-0.5	0.0
Glaucoma (self-reported)	0.2	0.2	1.6	-0.2	0.4	-0.1	-0.1	-0.1	0.2	-0.1	-0.3	-1.3	-0.5	-0.1	-0.0	0.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	1.8	-0.4	0.2	0.7	-0.2	-0.5	0.3	-0.3	-0.3	-1.4	-0.3	-0.3	-0.9	0.4
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.8	-0.2	-0.2	-0.3	0.2	0.0	-0.4	-0.7	-0.1	1.3	-0.0	0.1	-0.0	0.3
Neck or shoulder pain in last month	0.2	0.2	1.1	-0.5	0.1	-0.0	0.3	0.3	-0.2	-0.4	-0.5	1.1	0.9	0.3	0.5	-0.3
Medication: Blood pressure	0.2	0.3	0.8	-0.6	-0.0	-0.4	-0.9	-0.6	-0.7	-0.5	-0.8	0.3	0.3	-0.7	0.4	0.2
Arm fat percentage (left)	0.2	1.0	6.5	-0.3	0.1	-0.6	-0.6	0.2	-0.4	-0.1	-0.3	2.5	1.7	-0.2	0.8	-1.2
Ever had bowel cancer screening	0.2	0.2	0.5	-0.6	-0.7	-0.3	0.0	-0.4	-0.3	0.6	0.6	-0.4	0.1	-0.4	-0.1	-0.7
Qualifications: nursing, teaching	0.2	0.2	0.7	0.4	0.7	0.4	0.1	0.8	0.5	-0.3	0.1	0.6	0.8	0.5	0.1	0.2
Medication for cholesterol	0.2	0.4	1.5	-0.1	-0.4	0.3	-0.1	-0.1	-0.1	1.2	0.8	-1.1	-0.9	-0.2	0.0	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	1.1	-0.4	0.1	-0.1	-0.3	-0.2	-0.0	-0.6	-0.7	-1.0	0.1	-0.2	-1.1	0.0
Medication: Atorvastatin	0.2	0.3	0.9	-0.8	-0.8	0.1	-0.5	-0.6	-0.4	-0.0	-0.5	0.0	0.2	-0.7	-0.3	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.3	-0.2	-0.1	-1.1	-0.3	0.0	-0.4	-0.4	-0.3	1.1	0.1	0.0	-0.1	0.1
HbA1C	0.1	0.1	0.4	0.2	-0.6	-0.5	-0.4	-0.3	-0.2	-0.5	-0.4	-0.2	-0.0	0.1	-0.5	0.3
Ulcerative Colitis	0.1	0.2	0.6	-0.2	-0.4	0.6	0.1	-0.4	0.0	0.6	0.4	-0.7	-0.6	-0.6	0.3	-0.2
Allergy or Eczema	0.1	0.4	1.4	-1.0	-1.2	0.2	-0.3	-0.4	-0.5	0.4	0.1	-0.8	-0.7	-0.5	-0.0	-0.5
Maternal smoking around birth	0.1	0.2	1.1	-0.2	0.3	-0.3	0.1	0.2	-0.0	0.3	-0.1	-1.0	-0.2	0.3	-0.4	-0.6
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.6	-0.4	-0.7	0.3	-0.1	-0.0	0.0	0.0	-0.1	-0.7	-0.3	0.0	-0.0	0.0
Number of incorrect matches in round	0.1	0.2	1.3	0.2	0.0	-0.2	-0.0	0.2	0.4	0.3	0.7	-0.0	-1.1	0.3	0.5	0.8
Allergy	0.1	0.2	1.0	0.7	0.6	-1.0	-0.2	-0.1	-0.1	-0.6	-0.2	0.3	-0.0	-0.1	-0.6	0.5
Blood clot in the leg (DVT)	0.1	0.1	0.6	0.2	-0.7	0.2	-0.2	-0.1	0.1	-0.1	-0.4	-0.3	0.8	-0.1	0.0	0.2
Alcohol intake frequency.	0.1	0.2	1.4	-0.1	-0.2	-0.7	0.4	0.4	-0.3	-0.5	-0.1	1.2	-0.1	0.2	0.1	-0.1
Commuting to job workplace: Public transport	0.1	0.1	0.5	-0.2	-0.0	0.2	-0.0	0.2	0.2	-0.3	-0.7	-0.5	0.4	0.2	-0.1	0.2
Illnesses of father: High blood pressure	0.1	0.1	0.2	0.0	0.2	0.3	-0.4	-0.4	-0.1	0.5	0.1	-0.1	-0.2	-0.3	0.1	-0.5
Fractured/broken bones in last 5 years	0.1	0.1	0.4	0.0	-0.6	0.0	-0.1	-0.3	-0.3	0.2	-0.1	0.2	-0.0	-0.3	-0.4	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.7	-0.0	-0.8	0.1	-0.2	-0.2	-0.1	-0.3	-0.5	-0.3	0.7	-0.1	0.0	0.3

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