Hub : Genes

IMMT

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1650 0.0420 0.0e+00 0.205 0.105 0.199 0.073 0.091 2.0e-24 9.1e-13 1.2e-23 2.8e-09 3.4e-11
2 GTEx Adipose Subcutaneous 0.1120 0.0390 4.5e-07 0.097 NA 0.077 NA 0.077 2.5e-08 NA 7.1e-07 NA 7.0e-07
3 GTEx Artery Aorta 0.2380 0.0550 1.2e-12 0.242 NA 0.242 NA 0.242 1.5e-13 NA 1.4e-13 NA 1.4e-13
4 GTEx Artery Coronary 0.1050 0.0500 8.7e-03 0.017 NA 0.018 NA 0.027 8.8e-02 NA 8.1e-02 NA 4.1e-02
5 GTEx Artery Tibial 0.2197 0.0451 0.0e+00 0.294 NA 0.285 NA 0.303 2.4e-23 NA 1.5e-22 NA 3.9e-24
6 GTEx Brain Cerebellar Hemisphere 0.1560 0.0820 7.9e-03 0.067 NA 0.008 NA 0.034 8.7e-03 NA 1.9e-01 NA 4.7e-02
7 GTEx Brain Cerebellum 0.2560 0.0790 1.2e-05 0.156 NA 0.225 NA 0.193 2.4e-05 NA 2.8e-07 NA 2.3e-06
8 GTEx Brain Cortex 0.1470 0.0730 7.6e-03 0.125 NA 0.066 NA 0.110 2.7e-04 NA 6.8e-03 NA 6.2e-04
9 GTEx Brain Frontal Cortex BA9 0.1853 0.0709 4.9e-04 0.111 NA 0.093 NA 0.087 7.4e-04 NA 2.0e-03 NA 2.6e-03
10 GTEx Brain Nucleus accumbens basal ganglia 0.1800 0.0760 4.1e-03 0.014 NA 0.047 NA 0.044 1.4e-01 NA 2.2e-02 NA 2.5e-02
11 GTEx Brain Putamen basal ganglia 0.2060 0.0970 9.8e-03 0.067 NA 0.018 NA 0.028 1.1e-02 NA 1.2e-01 NA 7.3e-02
12 GTEx Breast Mammary Tissue (Female) 0.0539 0.0510 1.7e-01 -0.007 NA -0.003 NA 0.014 5.8e-01 NA 3.9e-01 NA 1.2e-01
13 GTEx Cells Transformed fibroblasts 0.1170 0.0380 4.7e-07 0.156 NA 0.107 NA 0.138 9.5e-12 NA 2.0e-08 NA 1.6e-10
14 GTEx Colon Sigmoid 0.2950 0.0780 2.1e-10 0.362 NA 0.333 NA 0.212 1.1e-13 NA 1.8e-12 NA 5.2e-08
15 GTEx Colon Transverse 0.2350 0.0620 5.1e-08 0.148 NA 0.140 NA 0.176 1.6e-07 NA 3.5e-07 NA 9.4e-09
16 GTEx Esophagus Gastroesophageal Junction 0.2980 0.0780 3.2e-09 0.366 NA 0.272 NA 0.329 3.6e-14 NA 2.2e-10 NA 1.3e-12
17 GTEx Esophagus Mucosa 0.1980 0.0500 8.8e-14 0.256 NA 0.236 NA 0.231 3.2e-17 NA 7.5e-16 NA 1.8e-15
18 GTEx Esophagus Muscularis 0.3140 0.0550 0.0e+00 0.403 NA 0.421 NA 0.272 4.5e-26 NA 1.5e-27 NA 1.0e-16
19 GTEx Lung 0.1788 0.0470 1.0e-11 0.202 NA 0.198 NA 0.198 2.3e-15 NA 4.0e-15 NA 4.2e-15
20 GTEx Nerve Tibial 0.1399 0.0403 1.2e-09 0.193 NA 0.162 NA 0.177 1.1e-13 NA 1.4e-11 NA 1.4e-12
21 GTEx Ovary 0.2810 0.1270 7.2e-03 0.046 NA 0.137 NA 0.141 2.9e-02 NA 3.2e-04 NA 2.5e-04
22 GTEx Pancreas 0.1770 0.0650 4.8e-05 0.129 NA 0.117 NA 0.151 4.2e-06 NA 1.3e-05 NA 6.5e-07
23 GTEx Prostate 0.2750 0.0870 1.3e-05 0.278 NA 0.209 NA 0.145 1.1e-07 NA 5.8e-06 NA 1.8e-04
24 GTEx Skin Not Sun Exposed Suprapubic 0.4070 0.0720 0.0e+00 0.377 NA 0.319 NA 0.335 8.6e-22 NA 5.1e-18 NA 4.6e-19
25 GTEx Skin Sun Exposed Lower leg 0.2640 0.0580 0.0e+00 0.297 NA 0.299 NA 0.267 6.2e-25 NA 4.5e-25 NA 3.5e-22
26 GTEx Spleen 0.1250 0.0560 4.6e-03 0.089 NA 0.057 NA 0.010 2.8e-03 NA 1.5e-02 NA 1.7e-01
27 GTEx Stomach 0.3310 0.1350 1.4e-03 0.022 NA 0.008 NA 0.025 2.9e-02 NA 1.3e-01 NA 2.2e-02
28 GTEx Testis 0.4160 0.0710 0.0e+00 0.474 NA 0.478 NA 0.427 1.7e-23 NA 9.9e-24 NA 1.4e-20
29 GTEx Thyroid 0.1130 0.0390 1.8e-06 0.091 NA 0.107 NA 0.112 1.7e-07 NA 1.4e-08 NA 6.9e-09
30 GTEx Vagina 0.2550 0.0980 2.6e-03 0.148 NA 0.067 NA 0.130 3.0e-04 NA 1.2e-02 NA 6.8e-04
31 GTEx Whole Blood 0.0640 0.0220 3.5e-06 0.045 NA 0.063 NA 0.054 4.9e-05 NA 1.9e-06 NA 1.0e-05
32 METSIM Adipose 0.1442 0.0305 0.0e+00 0.198 0.189 0.202 0.197 0.207 7.8e-29 1.5e-27 1.7e-29 1.1e-28 3.1e-30
33 NTR Blood 0.0405 0.0124 1.6e-12 0.046 0.041 0.046 0.042 0.049 1.4e-14 3.3e-13 1.0e-14 2.0e-13 2.3e-15
34 ROSMAP Brain Pre-frontal Cortex 0.1237 0.0275 0.0e+00 0.199 0.176 0.204 0.165 0.165 5.3e-25 4.4e-22 1.1e-25 1.3e-20 1.3e-20
35 YFS Blood 0.1424 0.0253 0.0e+00 0.268 0.207 0.264 0.103 0.111 1.5e-87 7.5e-66 2.1e-86 1.0e-31 2.0e-34
36 TCGA Bladder Urothelial Carcinoma 0.0530 0.0310 4.7e-05 0.036 0.034 0.034 NA 0.029 4.7e-04 6.4e-04 7.0e-04 NA 1.5e-03
37 TCGA Head and Neck Squamous Cell Carcinoma 0.0347 0.0237 6.5e-04 0.030 0.029 0.022 NA 0.026 2.3e-04 2.8e-04 1.3e-03 NA 5.8e-04
38 TCGA Brain Lower Grade Glioma 0.0569 0.0363 8.9e-05 0.002 0.026 0.023 NA 0.016 1.9e-01 5.7e-04 9.6e-04 NA 4.9e-03
39 TCGA Lung Adenocarcinoma 0.0392 0.0248 2.9e-05 0.029 0.029 0.022 NA 0.031 2.0e-04 2.0e-04 1.2e-03 NA 1.4e-04
40 TCGA Lung Squamous Cell Carcinoma 0.0586 0.0536 5.5e-04 0.042 0.031 0.037 NA 0.039 1.3e-05 1.5e-04 4.5e-05 NA 2.5e-05
41 TCGA Pancreatic Adenocarcinoma 0.0930 0.0530 2.2e-04 0.107 0.086 0.098 NA 0.105 3.2e-05 1.8e-04 6.6e-05 NA 3.8e-05
42 TCGA Prostate Adenocarcinoma 0.0957 0.0471 2.2e-07 0.056 0.051 0.060 NA 0.065 1.6e-06 4.2e-06 6.6e-07 NA 2.3e-07
43 TCGA Stomach Adenocarcinoma 0.0970 0.0530 6.9e-06 0.056 0.060 0.071 NA 0.082 6.7e-05 4.0e-05 8.1e-06 NA 1.5e-06
44 TCGA Testicular Germ Cell Tumors 0.1170 0.0790 5.9e-04 0.106 0.065 0.051 NA 0.052 1.4e-04 2.6e-03 6.9e-03 NA 6.3e-03
45 TCGA Thyroid Carcinoma 0.1070 0.0490 1.6e-11 0.120 0.099 0.117 NA 0.078 9.3e-12 7.2e-10 1.7e-11 NA 5.3e-08

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45
Bipolar Disorder (2018) 0.1 0.1 1.1 -0.1 -0.2 -0.3 0.1 -0.3 -0.2 -1.1 0.0 -0.2 -0.5 -0.5 0.2 0.2 0.1 -0.2 -0.0 0.1 -0.0 0.1 0.1 -0.8 -0.1 0.1 0.0 0.1 0.1 -0.3 0.2 -0.6 -0.2 -0.3 0.1 0.1 -0.2 0.2 -0.4 0.1 0.6 0.1 -0.2 0.4 -0.1 -0.2 0.2 0.2
Bipolar Disorder or Schizophrenia 0.1 0.2 1.7 -0.3 -0.1 -0.2 0.4 -0.1 -0.5 -0.9 0.3 0.1 -0.2 0.1 0.5 0.5 0.3 -0.1 -0.0 0.2 0.1 0.2 0.4 -1.3 -0.3 1.1 0.0 0.5 0.4 0.3 0.7 -0.9 0.0 0.1 0.2 0.6 0.1 0.6 0.2 0.1 0.7 0.2 -0.2 0.8 -0.3 -0.3 0.5 -0.0
Depressed Affect (Nagel 2018) 1.8 3.7 7.0 -1.8 -2.0 -1.9 -0.3 -1.3 -1.7 -2.3 -2.4 -1.9 -1.3 -2.2 -2.3 -2.2 -2.1 -1.8 -1.7 -2.1 -1.7 -2.4 -2.2 -1.4 -1.6 -1.8 -1.8 -1.7 -2.2 -1.7 -2.3 -1.8 -2.0 -2.6 -2.1 -2.4 -1.6 -2.3 -2.0 -2.0 -0.7 -2.0 -1.7 -2.0 -1.6 -1.4 -2.1 -2.4
Depression (Nagel 2018) 0.1 0.1 1.0 0.2 0.1 0.2 1.0 0.6 0.2 -0.3 -0.2 0.1 0.5 -0.3 -0.0 -0.0 0.0 0.0 0.3 0.1 0.4 -0.2 0.0 0.0 0.3 -0.1 0.3 0.4 -0.0 0.4 -0.0 -0.1 0.1 -0.5 0.1 -0.2 0.5 -0.1 0.1 0.1 0.7 0.1 0.4 0.1 0.3 0.5 0.0 -0.3
Intelligence (Savage-Jansen 2018) 1.7 5.3 13.4 -2.5 -2.5 -2.0 0.1 -1.5 -2.6 -2.7 -2.1 -2.9 -2.0 -1.9 -2.2 -2.2 -2.4 -1.8 -2.2 -2.6 -2.4 -2.7 -2.3 -2.1 -2.6 -1.9 -2.1 -1.3 -2.5 -0.9 -2.1 -3.7 -2.2 -2.8 -2.4 -2.2 -2.9 -2.3 -1.5 -2.6 -2.3 -2.3 -2.3 -2.4 -2.8 -1.6 -2.2 -2.5
Neuroticism (Nagel 2018) 2.9 6.9 12.6 -2.8 -2.8 -2.6 -0.5 -1.9 -2.8 -3.5 -2.9 -2.5 -1.5 -2.4 -2.9 -2.9 -2.9 -2.5 -2.5 -2.9 -2.6 -3.2 -2.9 -1.9 -2.7 -2.8 -2.6 -2.4 -2.8 -2.3 -2.9 -2.9 -2.9 -3.0 -2.8 -2.7 -2.3 -2.9 -2.5 -2.8 -1.0 -2.7 -2.4 -2.5 -2.6 -2.1 -2.7 -3.2
Schizophrenia (2018) 0.1 0.2 1.8 -0.3 0.0 -0.0 0.4 0.0 -0.4 -0.2 0.4 0.2 0.2 0.5 0.5 0.4 0.3 -0.0 -0.0 0.2 0.2 0.2 0.4 -1.0 -0.3 1.4 0.0 0.6 0.5 0.6 0.7 -0.7 0.2 0.3 0.1 0.7 0.3 0.6 0.6 0.1 0.4 0.2 -0.1 0.6 -0.3 -0.3 0.5 -0.2
Schizophrenia vs Biploar Disorder 0.3 0.5 1.4 -1.0 -0.8 -0.5 0.2 -0.8 -1.0 -0.3 -0.4 -0.9 -0.9 -0.4 -0.5 -0.6 -0.6 -0.3 -0.9 -0.6 -0.6 -0.7 -0.6 -0.4 -1.1 -0.3 -0.9 -0.4 -0.6 0.0 -0.2 -0.9 -0.0 -0.6 -0.7 -0.1 -0.7 -0.4 0.0 -0.8 -0.5 -0.7 -1.2 -0.3 -1.2 -0.8 -0.3 -0.9
Worry (Nagel 2018) 3.6 7.7 14.6 -3.1 -3.0 -2.8 -0.9 -2.2 -3.2 -3.8 -2.9 -2.7 -1.5 -2.6 -2.9 -2.9 -2.9 -2.7 -2.8 -3.0 -2.8 -3.3 -3.0 -2.1 -3.0 -2.9 -2.9 -2.6 -2.9 -2.4 -2.9 -3.4 -3.0 -2.8 -3.0 -2.4 -2.6 -2.9 -2.5 -3.0 -1.6 -2.9 -2.7 -2.4 -2.9 -2.3 -2.8 -3.2
Alzheimer’s Disease (in mother) 2.5 2.9 7.7 -1.9 -1.9 -1.5 0.0 -1.4 -1.8 -2.0 -1.9 -1.8 -2.2 -1.2 -1.6 -1.6 -1.9 -1.7 -1.6 -1.8 -1.3 -2.1 -1.7 -2.8 -2.1 -1.1 -1.6 -1.4 -1.7 -1.0 -1.5 -2.0 -1.4 -1.9 -1.8 -1.9 -1.6 -1.7 -1.5 -1.9 -0.3 -1.7 -1.8 -1.9 -2.0 -1.5 -1.4 -2.1
Alzheimer’s Disease (in father) 0.7 0.7 2.2 -1.0 -1.0 -0.7 -0.5 -0.8 -1.2 -1.2 -0.7 -1.1 -0.7 -0.3 -0.6 -0.6 -0.7 -0.7 -0.9 -0.8 -1.2 -0.8 -0.7 -1.3 -1.0 -1.1 -0.9 -0.6 -0.8 -0.7 -0.4 -1.5 -0.6 -1.0 -0.9 -0.7 -1.1 -0.6 -0.6 -0.9 -0.5 -0.8 -0.9 -0.4 -1.0 -0.6 -0.7 -1.0
Alzheimer’s Disease (including proxy) 2.6 3.8 12.1 -2.1 -2.0 -1.8 -0.1 -1.4 -2.2 -2.1 -1.9 -2.3 -1.8 -1.1 -1.7 -1.8 -2.1 -1.7 -1.7 -2.0 -1.9 -2.3 -1.8 -3.5 -2.4 -1.3 -1.9 -1.5 -2.0 -1.4 -1.7 -2.7 -1.9 -2.2 -2.2 -2.0 -2.0 -1.9 -1.7 -2.1 -0.5 -1.9 -2.0 -1.9 -2.2 -1.7 -1.7 -2.4
Crohns Disease (2017) 0.3 0.7 2.3 0.6 0.7 0.7 0.6 0.7 0.4 0.1 0.9 1.0 0.8 1.1 1.0 1.0 0.9 0.8 0.8 0.9 0.7 1.0 1.0 1.1 0.6 1.5 0.8 1.0 1.1 0.9 1.1 -0.1 0.9 0.8 0.9 0.7 1.1 1.1 0.8 0.7 0.8 0.8 0.7 1.0 0.6 -0.0 0.9 0.6
Irritable Bowel Disease (IBD) 1.8 4.3 6.9 2.0 2.1 1.8 1.2 1.7 2.0 1.8 2.0 2.4 2.6 2.2 2.2 2.2 2.2 1.9 2.0 2.3 1.8 2.4 2.2 2.1 1.8 2.5 2.0 1.9 2.4 2.0 2.2 2.1 1.9 2.3 2.3 2.0 2.6 2.3 2.0 2.1 1.8 2.0 1.9 2.4 1.8 1.0 2.2 2.0
Ulcerative Colitis (UC) 3.2 6.0 10.8 2.5 2.5 2.2 1.8 2.2 2.6 2.5 2.3 2.8 3.3 2.4 2.5 2.5 2.6 2.4 2.4 2.7 2.2 2.6 2.5 2.0 2.2 2.6 2.4 2.0 2.7 2.4 2.4 2.9 2.2 2.7 2.7 2.4 2.8 2.6 2.5 2.5 2.1 2.4 2.3 2.6 2.2 1.6 2.5 2.4
Major Depression (MDD) 0.1 0.1 0.8 -0.3 -0.3 -0.3 -0.5 -0.4 -0.5 -0.7 -0.3 -0.2 -0.4 -0.3 -0.2 -0.2 -0.1 -0.2 -0.3 -0.2 -0.2 -0.1 -0.3 -0.5 0.1 -0.5 -0.3 -0.3 -0.3 -0.4 -0.2 -0.8 0.3 -0.4 -0.2 -0.0 -0.5 -0.3 -0.2 -0.2 -0.7 -0.3 -0.2 -0.4 0.0 0.9 -0.2 -0.1
Reaction Time 3.4 6.4 11.8 2.9 2.6 2.9 1.4 2.1 3.1 3.0 2.1 2.4 2.0 2.1 2.3 2.4 2.5 2.8 2.6 2.8 2.5 2.7 2.5 2.8 2.5 2.2 2.6 2.5 2.4 1.9 2.4 3.4 2.5 2.8 2.8 2.6 2.5 2.4 2.1 2.9 1.9 2.5 2.7 2.4 2.6 2.5 2.6 2.9
Verbal and Numeric Reasoning (VNR) 1.8 4.4 11.2 -2.4 -2.3 -2.2 0.5 -1.3 -2.4 -2.9 -1.8 -2.5 -2.0 -1.7 -1.9 -1.9 -2.2 -1.9 -2.0 -2.3 -2.2 -2.6 -1.9 -2.1 -2.5 -1.9 -1.9 -1.6 -2.1 -0.9 -1.7 -3.4 -2.1 -2.7 -2.2 -2.3 -2.3 -1.9 -1.6 -2.4 -0.5 -2.0 -2.2 -2.2 -2.5 -2.0 -1.8 -2.6
Breast Cancer 0.2 0.4 2.4 -0.7 -0.7 -0.3 0.0 -0.5 -0.9 -0.8 -0.5 -0.9 -1.2 -0.2 -0.5 -0.5 -0.6 -0.4 -0.5 -0.6 -0.7 -0.6 -0.6 -0.9 -0.6 -0.2 -0.5 -0.2 -0.7 -0.3 -0.4 -1.6 -0.3 -0.6 -0.6 -0.4 -0.7 -0.5 -0.3 -0.8 -0.5 -0.5 -0.7 -0.4 -0.7 -1.0 -0.5 -0.7
Ovarian Cancer 0.6 0.8 2.3 -1.3 -1.0 -1.0 -0.7 -1.0 -1.1 -0.6 -0.8 -1.1 -1.1 -1.0 -0.7 -0.7 -0.8 -0.7 -1.2 -0.8 -0.8 -0.9 -0.7 -1.5 -1.4 -0.7 -1.1 -0.8 -0.8 -0.3 -0.4 -0.7 -0.5 -0.9 -1.0 -0.4 -0.8 -0.6 -0.2 -0.9 -0.2 -0.9 -1.2 -0.3 -1.5 -0.8 -0.3 -1.2
Prostate Cancer 1.6 2.2 6.5 1.3 1.5 1.0 0.2 1.0 1.2 1.4 1.6 1.5 1.2 1.2 1.6 1.6 1.8 1.5 1.2 1.6 1.4 1.7 1.6 0.6 1.7 0.8 1.2 1.6 1.6 1.3 1.5 1.4 2.0 1.5 1.5 1.9 1.3 1.6 1.7 1.6 -0.1 1.5 1.1 1.7 1.7 2.5 1.7 1.6
Age at First Birth 0.4 0.5 1.5 -0.8 -0.7 -0.6 -0.1 -0.5 -0.7 -0.7 -0.7 -0.7 -0.0 -0.2 -0.7 -0.7 -0.9 -0.4 -0.7 -0.9 -0.4 -0.9 -0.7 -0.7 -1.1 -0.3 -0.8 -0.3 -0.8 -0.3 -0.8 -0.6 -0.6 -0.4 -0.7 -0.5 -0.8 -0.8 -0.3 -0.9 -0.9 -0.7 -0.8 -1.0 -1.2 -1.1 -0.8 -0.7
Bipolar Disorder (2011) 2.4 2.4 4.0 -1.2 -1.6 -1.8 -0.7 -1.1 -1.3 -2.0 -1.6 -1.5 -1.3 -1.8 -1.7 -1.6 -1.7 -1.2 -1.1 -1.6 -1.7 -1.6 -1.7 -1.3 -1.3 -1.4 -1.3 -1.5 -1.6 -1.5 -1.8 -1.5 -1.7 -2.0 -1.4 -1.8 -1.5 -1.7 -2.0 -1.5 -1.2 -1.4 -0.9 -1.7 -1.3 -1.6 -1.9 -1.1
Body Mass Index (BMI) (2010) 0.3 0.5 1.1 -0.7 -0.8 -0.9 -0.7 -0.8 -0.8 -0.7 -0.8 -0.8 -0.4 -0.3 -0.7 -0.7 -0.6 -0.3 -0.7 -0.7 -0.7 -0.6 -0.8 -0.6 -0.2 -0.5 -0.7 -0.5 -0.8 -0.9 -0.8 -0.8 -0.5 -0.9 -0.6 -0.4 -0.7 -0.8 -0.7 -0.5 -1.1 -0.8 -0.6 -0.5 -0.2 -0.0 -0.8 -0.6
Coronary Artery Disease (CAD) 0.5 0.6 5.2 -0.7 -0.7 -0.6 0.5 -0.1 -1.0 -1.4 -0.4 -0.2 -0.5 0.0 -0.2 -0.2 -0.7 -0.9 -0.3 -0.7 -0.6 -0.5 -0.4 -1.2 -0.9 -0.2 -0.2 -0.4 -0.2 0.2 -0.1 -2.3 -0.2 -1.0 -0.4 -1.1 -0.4 -0.3 -0.8 -0.9 0.4 -0.4 -0.3 -0.6 -0.9 -1.6 -0.7 -0.8
Crohns Disease (2012) 0.4 0.6 1.5 -1.0 -0.8 -1.0 -0.9 -1.1 -1.1 -1.0 -0.2 -0.8 -1.2 -1.1 -0.4 -0.4 -0.6 -1.0 -1.0 -0.7 -0.6 -0.5 -0.5 -0.1 -1.1 -0.6 -0.9 -0.4 -0.5 -0.7 -0.3 -1.2 -0.9 -0.6 -0.8 -0.7 -0.8 -0.3 -0.6 -0.8 -0.4 -0.7 -0.9 -0.3 -1.1 -1.2 -0.5 -0.8
Mean Putamen Volume 0.1 0.1 0.4 0.1 -0.1 -0.4 0.6 0.3 0.2 -0.1 -0.4 -0.1 0.0 0.0 -0.3 -0.3 -0.2 0.3 0.1 -0.3 -0.3 -0.4 -0.3 0.0 0.3 0.6 0.1 -0.2 -0.3 -0.1 -0.5 0.3 -0.4 -0.5 -0.0 -0.3 -0.1 -0.4 -0.3 -0.1 -0.1 -0.1 0.2 -0.6 0.2 -0.4 -0.5 -0.0
Fasting Glucose 1.2 1.5 5.7 1.5 1.1 1.1 1.1 1.5 1.5 1.9 0.7 1.4 1.9 2.4 0.7 0.8 0.9 1.4 1.5 1.1 0.8 0.9 0.8 1.2 1.4 1.2 1.4 0.7 1.0 0.9 0.7 0.9 0.9 0.9 1.3 0.9 1.7 0.7 0.7 1.2 1.3 1.1 1.4 1.0 1.4 1.1 0.8 1.1
HbA1C 0.5 0.6 2.9 0.7 0.6 0.9 -0.1 0.5 0.6 0.3 0.4 0.8 0.9 1.0 0.5 0.5 0.7 1.0 0.7 0.8 0.5 0.9 0.5 1.7 0.8 0.6 0.6 1.0 0.6 0.3 0.5 0.4 0.8 0.7 0.9 1.1 0.7 0.6 0.6 1.0 -0.0 0.6 0.9 1.0 0.9 1.2 0.6 1.0
HDL Cholesterol 0.9 1.4 4.9 0.7 1.4 1.1 0.7 0.6 0.9 1.2 1.6 0.3 -0.5 -0.3 1.6 1.5 1.4 1.3 0.5 1.3 1.5 1.1 1.5 0.1 0.9 0.6 0.8 1.6 1.1 1.3 1.5 0.9 0.9 1.4 0.9 1.8 0.4 1.4 2.0 1.2 0.3 1.1 0.4 1.6 0.8 2.2 1.8 0.9
LDL Cholesterol 0.1 0.2 0.9 -0.2 -0.3 -0.4 -1.0 -0.5 -0.3 -0.5 -0.5 0.4 0.7 0.7 -0.5 -0.5 -0.2 -0.2 -0.2 -0.2 -0.7 -0.1 -0.5 -0.0 0.1 -0.5 -0.4 -0.5 -0.2 -0.9 -0.6 0.4 -0.5 -0.0 -0.2 -0.4 -0.1 -0.4 -0.7 -0.1 -0.2 -0.3 -0.1 -0.6 0.3 -0.2 -0.5 -0.0
Lupus 0.5 0.7 2.0 1.1 0.9 0.7 -0.1 0.5 1.1 0.8 0.5 0.8 1.1 1.0 0.7 0.7 0.9 1.2 0.9 0.9 0.6 1.1 0.7 0.3 1.2 0.9 0.8 1.0 0.7 0.2 0.5 1.4 0.7 0.8 0.9 0.8 0.7 0.7 0.6 1.0 -0.3 0.8 0.8 0.6 1.2 1.1 0.5 1.3
Neuroticism (2016) 0.1 0.1 0.7 0.0 -0.0 -0.2 0.3 0.5 -0.2 -0.5 -0.1 -0.1 0.1 -0.3 -0.2 -0.2 -0.2 0.2 0.2 -0.1 -0.0 -0.2 -0.2 0.5 0.1 -0.5 0.0 0.0 -0.2 -0.0 -0.3 -0.8 -0.7 -0.3 -0.1 -0.3 0.1 -0.2 -0.0 -0.2 -0.1 -0.0 0.1 -0.3 0.1 0.4 -0.2 -0.3
Primary Biliary Cirrhosis 0.2 0.3 0.9 0.5 0.3 0.4 0.2 0.3 0.4 0.4 0.4 0.8 0.4 0.4 0.4 0.4 0.4 0.6 0.5 0.5 0.5 0.5 0.4 -0.1 0.2 0.9 0.4 0.2 0.6 0.4 0.5 0.7 0.7 0.3 0.6 0.8 0.7 0.4 0.3 0.5 0.7 0.4 0.3 0.8 0.3 -0.2 0.5 0.6
Rheumatoid Arthritis 1.7 2.3 4.1 1.7 1.5 1.5 1.6 1.8 1.7 1.2 1.2 1.6 1.9 1.8 1.4 1.4 1.4 1.6 1.7 1.4 1.4 1.4 1.4 2.0 1.6 1.5 1.7 1.7 1.5 1.3 1.3 1.3 0.7 1.5 1.6 1.1 1.8 1.4 1.2 1.5 1.4 1.6 1.8 1.2 1.6 1.1 1.2 1.5
Schizophrenia (2014) 0.1 0.3 3.5 -0.7 -0.4 -0.2 0.9 -0.0 -0.8 -0.7 0.0 0.0 0.0 0.3 0.2 0.1 -0.0 -0.3 -0.3 -0.2 -0.2 -0.3 0.1 -1.9 -0.7 1.2 -0.3 0.2 0.2 0.6 0.4 -1.3 0.0 -0.4 -0.2 0.3 0.1 0.2 0.2 -0.4 0.6 -0.1 -0.6 0.2 -0.7 -1.2 0.1 -0.6
Triglycerides 0.0 0.1 0.3 0.3 0.0 0.3 -0.4 0.0 0.2 0.0 -0.1 0.6 0.6 0.5 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.4 0.1 0.4 0.4 0.4 0.2 0.0 0.3 -0.1 0.1 0.5 0.3 0.3 0.3 0.1 0.3 0.2 -0.1 0.2 -0.1 0.3 0.3 -0.1 0.4 -0.2 -0.1 0.3
Type 2 Diabetes (T2D) (2012) 5.9 6.8 9.6 -2.8 -2.7 -2.5 -1.6 -2.4 -2.5 -2.5 -2.4 -2.4 -3.0 -2.7 -2.4 -2.4 -2.8 -3.0 -2.8 -2.9 -2.5 -2.8 -2.5 -2.2 -2.7 -2.2 -2.5 -2.6 -2.7 -1.9 -2.5 -2.2 -1.8 -2.8 -2.6 -2.7 -2.6 -2.8 -2.2 -2.9 -2.4 -2.7 -2.8 -3.1 -3.0 -3.0 -2.9 -2.9
Ulcerative Colitis 1.4 2.0 5.0 1.3 1.3 1.1 1.3 1.3 1.4 1.4 1.3 1.8 2.2 1.8 1.5 1.5 1.4 1.5 1.3 1.5 1.1 1.4 1.5 1.3 1.1 1.6 1.4 1.0 1.6 1.5 1.4 1.4 0.9 1.4 1.5 1.4 1.7 1.5 1.5 1.4 1.5 1.4 1.2 1.6 1.1 1.1 1.6 1.2
Blood Eosinophil Count 1.5 11.5 18.5 3.1 3.3 3.9 1.6 2.6 3.0 3.1 3.5 3.2 3.1 2.2 3.7 3.6 3.6 3.2 3.0 3.6 3.8 3.9 3.6 2.7 2.8 4.0 3.0 3.6 3.6 3.3 3.7 2.9 4.0 4.2 3.5 4.2 3.2 3.8 4.0 3.5 1.5 3.4 3.0 4.3 2.6 3.4 3.8 3.5
Blood Platelet Count 1.6 19.1 28.4 -4.5 -4.7 -4.4 -3.0 -4.1 -4.8 -5.3 -4.8 -4.2 -2.7 -2.8 -4.6 -4.5 -4.7 -4.4 -4.2 -4.8 -4.5 -4.5 -4.7 -1.5 -3.9 -4.3 -4.3 -4.4 -4.5 -4.8 -4.7 -5.3 -4.6 -4.1 -4.4 -4.7 -4.7 -4.7 -5.1 -4.6 -3.3 -4.5 -4.0 -5.0 -3.9 -3.3 -4.9 -4.3
Blood Red Count 0.1 0.8 4.9 -0.0 -0.7 -0.6 -0.8 -0.1 -0.1 -1.7 -1.1 1.3 2.2 1.1 -0.7 -0.6 -0.8 -0.9 0.1 -0.6 -1.0 -0.3 -0.7 0.8 -0.3 0.7 -0.1 -1.2 0.0 -1.1 -0.9 0.4 -0.1 -0.3 -0.1 -1.2 1.2 -0.7 -1.6 -0.5 0.7 -0.4 0.3 -0.7 -0.2 -1.8 -1.2 -0.3
Blood White Count 0.2 1.6 8.0 1.6 1.1 1.7 2.0 1.9 1.6 0.7 0.4 1.6 1.3 1.1 0.6 0.7 0.8 1.4 1.8 1.0 1.3 0.9 0.8 0.7 1.4 2.8 1.6 1.1 1.0 1.3 0.8 0.8 1.6 0.9 1.3 0.4 1.7 0.7 0.7 1.0 1.3 1.2 1.7 0.5 1.4 0.4 0.6 1.2
Heel T-Score 0.1 0.4 1.6 -0.7 -0.5 -0.8 -0.4 -0.4 -0.9 -1.3 -0.0 -0.5 1.0 -1.0 -0.4 -0.4 -0.5 -0.6 -0.6 -0.5 -0.4 -0.5 -0.5 -0.4 -0.6 -1.2 -0.7 -0.8 -0.4 0.0 -0.6 -1.0 -1.0 -0.7 -0.6 -0.4 -0.4 -0.4 -0.3 -0.6 -0.6 -0.5 -0.6 -0.4 -0.6 -1.1 -0.5 -0.6
BMI 0.7 3.9 7.8 2.0 2.0 1.8 1.8 2.1 1.9 2.1 1.6 1.9 1.1 2.6 1.8 1.9 1.9 2.5 2.2 1.9 1.8 1.9 1.9 -1.3 1.8 2.8 2.1 2.5 1.9 2.3 2.0 1.3 2.1 1.3 2.1 2.2 1.9 1.9 2.2 1.9 1.0 2.0 2.1 2.1 1.7 1.8 1.9 2.0
Height 0.0 0.5 7.1 0.6 0.6 1.1 0.5 0.6 0.7 1.3 0.3 -0.2 0.4 0.4 0.3 0.4 0.3 1.5 0.4 0.0 0.5 0.2 0.5 2.7 0.4 0.4 0.3 0.4 -0.1 0.5 0.1 0.9 1.0 0.6 0.4 0.4 -0.1 0.2 1.1 0.3 -1.9 -0.0 0.2 0.1 0.1 0.9 0.1 0.6
Waist Hip Ratio (WHR) 0.6 2.6 3.9 -1.6 -1.7 -1.7 -1.2 -1.6 -1.6 -1.9 -1.7 -1.5 -1.3 -1.6 -1.7 -1.7 -1.7 -1.7 -1.7 -1.7 -1.8 -1.6 -1.7 -0.4 -1.5 -2.0 -1.6 -1.5 -1.6 -1.6 -1.7 -1.5 -1.5 -1.4 -1.7 -1.8 -1.5 -1.7 -1.6 -1.8 -1.4 -1.7 -1.5 -1.7 -1.6 -2.0 -1.8 -1.6
Systolic Blood Pressure 4.4 21.9 39.2 -5.1 -5.0 -4.8 -0.0 -3.1 -5.0 -4.3 -4.2 -5.0 -5.8 -5.3 -4.3 -4.3 -5.0 -4.7 -4.5 -4.8 -3.9 -5.6 -4.4 -5.0 -5.8 -5.0 -4.4 -4.5 -4.5 -2.7 -3.9 -5.9 -4.9 -5.2 -5.0 -5.2 -3.9 -4.3 -3.9 -5.2 0.4 -4.5 -4.7 -4.2 -5.7 -5.5 -4.0 -6.3
Smoking Status 0.6 1.5 9.6 1.6 1.2 1.2 -0.8 0.4 1.8 2.0 0.4 1.1 0.9 0.1 0.5 0.6 0.9 0.9 1.1 1.1 1.1 1.3 0.7 2.9 1.8 1.7 1.0 0.8 0.7 0.0 0.3 3.1 0.8 1.1 1.0 0.6 0.8 0.5 0.5 1.3 -0.9 0.8 1.2 0.5 1.7 1.0 0.4 1.8
Allergy or Eczema 0.6 1.6 3.5 1.2 1.2 1.5 1.4 1.4 1.0 0.2 1.3 1.5 1.9 0.9 1.5 1.5 1.1 1.1 1.4 1.2 1.2 1.2 1.4 0.8 0.9 1.3 1.5 1.3 1.4 1.3 1.4 -0.0 1.0 1.8 1.3 1.0 1.7 1.4 1.1 1.1 1.7 1.5 1.5 1.0 0.9 0.6 1.2 1.1
Cardiovascular Disease 2.8 9.1 23.9 -3.0 -3.1 -3.2 0.9 -1.3 -2.9 -2.3 -2.7 -3.7 -3.8 -3.7 -2.7 -2.7 -3.2 -2.3 -2.5 -3.1 -2.3 -3.7 -2.7 -4.9 -3.8 -2.5 -2.5 -2.5 -3.1 -0.9 -2.4 -4.3 -3.2 -4.1 -3.2 -3.3 -2.7 -2.8 -2.1 -3.4 0.0 -2.7 -2.7 -2.7 -3.8 -3.8 -2.6 -3.9
Hypothyroidism (self reported) 0.2 0.4 2.3 0.6 0.6 0.3 0.0 0.5 0.8 1.0 0.3 0.1 0.7 0.1 0.3 0.3 0.6 1.1 0.5 0.6 0.3 0.5 0.4 1.5 0.6 0.4 0.4 0.6 0.2 0.5 0.2 1.1 0.6 0.9 0.4 0.9 0.2 0.4 0.8 0.6 -0.5 0.4 0.5 0.8 0.6 1.1 0.5 0.7
Respiratory disease 2.5 5.6 7.5 2.2 2.5 2.3 2.4 2.6 2.2 2.1 2.5 2.5 2.7 2.7 2.5 2.5 2.3 2.6 2.4 2.4 2.4 2.2 2.5 0.6 1.9 2.4 2.4 2.6 2.5 2.7 2.6 1.7 2.3 2.4 2.4 2.2 2.7 2.5 2.7 2.2 2.3 2.5 2.3 2.1 1.9 1.8 2.5 2.0
Type 2 Diabetes (T2D) (2018) 0.2 0.3 1.3 -0.2 -0.5 -0.3 -0.5 -0.4 -0.0 0.2 -0.9 -0.1 -0.1 -1.1 -0.8 -0.8 -0.8 -0.3 -0.3 -0.6 -0.2 -0.5 -0.7 -0.1 -0.4 -0.3 -0.4 -0.5 -0.6 -0.5 -0.8 0.7 -0.2 -0.6 -0.4 -0.8 -0.2 -0.8 -0.6 -0.6 -0.8 -0.6 -0.3 -0.6 -0.6 -0.8 -0.9 -0.2
Lung FEV1/FVC ratio 4.8 24.1 34.7 -4.6 -5.0 -4.9 -3.2 -4.5 -4.5 -5.1 -5.3 -5.0 -3.0 -4.2 -5.7 -5.6 -5.4 -4.5 -4.7 -5.3 -5.2 -5.3 -5.6 -2.7 -4.4 -4.1 -5.0 -4.8 -5.5 -5.2 -5.9 -3.5 -5.2 -4.9 -5.1 -5.0 -5.0 -5.7 -5.3 -5.1 -4.2 -5.3 -4.8 -5.2 -4.5 -5.2 -5.7 -4.6
Lung FVC 0.6 3.1 5.5 1.9 1.9 1.6 0.8 1.6 1.7 1.0 1.9 2.0 2.3 1.3 1.9 1.9 2.0 1.7 1.9 1.9 1.6 2.1 1.8 1.8 2.4 1.4 1.9 1.8 1.9 1.2 1.6 1.3 1.4 2.0 1.9 1.9 1.6 1.8 1.5 1.9 0.2 1.9 2.0 1.6 2.3 1.6 1.5 2.3
Neuroticism 3.8 9.2 14.1 -2.8 -3.2 -2.8 -0.9 -2.2 -2.8 -3.8 -3.7 -3.0 -2.1 -3.0 -3.5 -3.5 -3.4 -2.8 -2.8 -3.3 -3.0 -3.6 -3.4 -2.1 -2.7 -3.0 -2.9 -2.9 -3.4 -2.9 -3.6 -2.7 -3.4 -3.4 -3.2 -3.3 -2.7 -3.5 -3.2 -3.2 -1.6 -3.2 -2.8 -3.1 -2.7 -2.5 -3.3 -3.4
Chronotype (morning person) 0.4 0.9 3.0 -1.2 -0.9 -1.1 -0.2 -0.7 -1.3 -1.6 -0.5 -1.1 -1.7 -1.2 -0.6 -0.7 -0.7 -0.3 -1.0 -0.9 -0.6 -0.9 -0.7 -1.7 -1.1 -0.9 -1.0 -0.5 -0.9 -0.4 -0.6 -1.6 -0.7 -1.1 -0.9 -0.4 -1.2 -0.7 -0.5 -0.9 -0.6 -0.8 -1.1 -0.7 -1.0 0.3 -0.5 -1.1
Hair Pigment 0.2 4.9 7.3 -2.2 -2.3 -2.4 -2.1 -2.2 -2.3 -2.7 -2.3 -2.1 -2.1 -1.4 -2.2 -2.2 -2.3 -2.4 -2.2 -2.4 -2.5 -2.1 -2.3 -1.6 -1.9 -2.3 -2.2 -2.0 -2.2 -2.4 -2.2 -2.2 -2.4 -2.5 -2.2 -2.4 -2.4 -2.2 -2.5 -2.3 -2.1 -2.2 -2.1 -2.5 -1.9 -1.7 -2.4 -2.0
Tanning 0.1 0.9 5.0 1.1 0.8 0.9 -0.3 0.5 1.2 0.8 0.4 1.3 1.2 1.1 0.7 0.7 0.8 1.0 1.0 1.0 0.7 1.2 0.8 2.2 0.9 1.4 0.9 0.6 0.9 0.4 0.7 1.6 0.8 0.8 1.1 0.6 1.1 0.7 0.4 1.0 0.2 0.8 1.1 0.8 0.9 0.6 0.6 1.3
Hand grip strength (left) 0.5 1.2 3.1 1.0 1.2 0.6 0.3 1.1 0.8 1.3 1.0 1.0 0.6 1.5 1.1 1.1 1.2 1.6 1.1 1.1 0.9 1.2 1.1 0.1 1.2 1.8 1.1 1.4 1.1 1.1 1.1 0.7 1.0 1.0 1.1 1.7 1.0 1.1 1.4 1.1 -0.5 1.1 1.1 1.3 1.0 0.8 0.9 1.3
Number of treatments/medications taken 1.3 2.3 4.3 -1.5 -1.6 -1.6 -0.6 -1.5 -1.2 -0.8 -1.5 -1.8 -2.0 -1.7 -1.5 -1.5 -1.6 -1.6 -1.5 -1.5 -1.4 -1.7 -1.5 -2.0 -1.7 -1.2 -1.5 -1.5 -1.6 -1.2 -1.3 -1.0 -1.4 -1.9 -1.7 -2.1 -1.4 -1.5 -1.5 -1.5 -0.3 -1.5 -1.4 -1.7 -1.6 -1.3 -1.3 -1.7
Average weekly spirits intake 0.3 0.4 3.3 0.2 -0.2 -0.4 -1.6 -0.5 0.2 -0.1 -1.0 -0.0 0.2 -0.8 -0.6 -0.6 -0.3 -0.1 -0.0 -0.3 -0.4 0.1 -0.5 1.0 0.4 0.5 -0.2 -0.4 -0.4 -1.1 -0.9 1.0 -0.6 -0.2 -0.2 -0.4 -0.2 -0.6 -0.6 -0.1 -1.8 -0.3 0.2 -0.7 0.4 -0.2 -0.9 0.5
Sensitivity / hurt feelings 0.0 0.1 1.3 0.1 0.1 0.3 0.3 0.2 0.1 -0.4 0.1 0.2 1.2 0.7 -0.0 0.0 0.1 -0.0 0.1 0.1 -0.2 0.0 0.0 -0.1 0.2 0.0 0.0 -0.2 0.1 -0.1 -0.1 0.4 0.3 0.4 0.0 0.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.3 0.2 -0.2 0.1 -0.1
Frequency of depressed mood in last 2 weeks 1.1 1.5 3.2 -0.9 -1.2 -1.0 0.0 -0.4 -0.8 -1.2 -1.6 -1.2 -0.8 -1.3 -1.7 -1.6 -1.5 -1.1 -0.8 -1.4 -0.9 -1.6 -1.5 -0.6 -0.9 -1.1 -1.0 -0.9 -1.6 -1.2 -1.6 -1.0 -1.4 -1.6 -1.3 -1.8 -0.8 -1.7 -1.4 -1.3 -0.6 -1.3 -0.7 -1.6 -0.9 -0.9 -1.6 -1.4
Hearing difficulty/problems: Yes 0.6 0.9 5.2 -1.2 -0.8 -0.5 -1.1 -1.0 -1.2 -1.0 -0.7 -1.0 -2.3 -2.1 -0.7 -0.7 -0.7 -0.8 -1.2 -0.8 -0.5 -0.8 -0.7 -0.9 -1.0 -1.0 -1.1 -0.8 -0.8 -0.7 -0.6 -0.7 -0.5 -0.8 -1.0 -0.5 -1.1 -0.7 -0.5 -0.9 -0.8 -0.9 -1.3 -0.5 -1.0 -0.5 -0.6 -1.0
Relative age of first facial hair 0.0 0.1 0.7 0.1 0.2 0.2 0.8 0.2 0.2 0.1 0.3 -0.0 0.1 -0.2 0.2 0.2 0.1 0.1 0.1 0.2 -0.0 0.0 0.2 0.3 -0.2 0.4 0.1 0.2 0.1 0.6 0.3 0.1 0.1 0.1 0.2 0.2 0.1 0.3 0.3 0.2 0.7 0.2 0.0 0.2 -0.3 -0.3 0.4 0.1
Other serious medical condition/disability diagnosed by doctor 2.3 2.9 4.9 2.0 1.8 1.9 1.5 1.8 2.0 1.8 1.2 1.7 1.6 0.9 1.5 1.6 1.7 1.8 2.0 1.8 1.8 1.6 1.6 0.6 1.9 2.2 1.9 1.7 1.6 1.7 1.5 1.6 1.8 1.4 1.8 1.4 2.0 1.6 1.3 1.9 1.9 1.8 2.0 1.6 2.0 1.9 1.6 1.6
Ever used hormone-replacement therapy (HRT) 0.1 0.1 1.3 0.2 0.2 0.5 1.2 0.4 0.2 -0.1 0.3 0.2 0.1 0.0 0.3 0.3 0.2 -0.1 0.3 0.2 0.2 0.0 0.3 -0.3 0.1 0.6 0.3 0.3 0.2 0.4 0.3 -0.3 0.2 0.5 0.1 -0.1 0.3 0.3 0.1 0.2 1.1 0.3 0.1 0.0 0.2 0.0 0.4 -0.0
Ever had hysterectomy (womb removed) 1.7 1.9 5.2 -1.1 -1.3 -1.5 -2.3 -1.8 -1.1 -0.8 -1.6 -1.3 -0.7 -1.3 -1.6 -1.6 -1.4 -1.2 -1.3 -1.3 -1.8 -1.1 -1.6 -0.5 -1.0 -0.7 -1.4 -1.7 -1.5 -2.2 -1.8 -0.3 -1.5 -0.8 -1.4 -1.0 -1.1 -1.6 -1.6 -1.2 -1.9 -1.5 -1.2 -1.0 -1.0 -1.2 -1.6 -0.9
Systolic blood pressure, automated reading 3.5 10.2 19.5 -3.7 -3.5 -3.3 -0.8 -2.6 -3.6 -2.9 -2.7 -2.9 -2.8 -3.3 -2.8 -2.9 -3.3 -3.8 -3.4 -3.3 -2.8 -3.6 -2.9 -3.4 -4.1 -3.5 -3.2 -3.7 -2.8 -2.1 -2.6 -3.8 -3.2 -3.1 -3.4 -3.5 -2.4 -2.8 -2.7 -3.6 -0.0 -3.1 -3.4 -2.8 -4.0 -4.4 -2.8 -4.2
Eye problems/disorders: Diabetes related eye disease 0.3 0.4 1.3 -0.4 -0.6 -0.8 -1.2 -0.7 -0.3 -0.2 -0.8 -0.3 0.1 -0.3 -0.7 -0.7 -0.7 -0.6 -0.5 -0.6 -0.8 -0.5 -0.6 -0.0 -0.3 -0.4 -0.5 -0.9 -0.5 -1.2 -0.9 0.1 -0.8 -0.5 -0.5 -0.8 -0.1 -0.7 -1.0 -0.5 -0.2 -0.6 -0.3 -0.9 -0.2 -0.7 -0.8 -0.4
Angina 0.8 1.1 3.4 -1.1 -1.2 -1.0 0.1 -0.8 -1.0 -0.9 -0.9 -1.0 -1.7 -1.4 -0.9 -0.9 -1.1 -0.6 -1.0 -1.0 -0.7 -1.2 -0.9 -1.9 -1.5 -0.5 -1.0 -0.9 -1.0 -0.6 -0.6 -1.0 -0.9 -1.5 -1.0 -0.9 -1.1 -0.9 -0.8 -1.1 0.1 -1.0 -1.2 -0.7 -1.5 -1.1 -0.6 -1.2
Medication for hormone replacement therapy 0.5 0.5 1.7 1.1 0.9 0.7 0.4 0.8 1.1 0.8 0.5 0.9 0.5 0.8 0.4 0.4 0.5 0.4 1.0 0.6 0.7 0.6 0.5 1.1 1.1 0.5 0.9 0.7 0.5 0.0 0.2 1.3 0.1 0.8 0.7 -0.1 0.7 0.3 -0.1 0.8 0.7 0.7 1.1 -0.2 1.2 1.0 0.3 0.9
Vitamin and mineral supplements 0.5 0.7 2.7 0.6 0.5 0.8 1.5 1.3 0.3 -0.4 0.6 0.8 1.0 0.4 0.9 0.9 0.7 0.7 0.9 0.6 0.8 0.5 0.8 -0.6 0.5 0.5 0.9 0.6 0.9 1.0 0.9 -1.0 0.8 0.2 0.7 0.6 1.0 0.9 0.5 0.6 1.6 0.9 0.9 0.9 0.6 1.0 0.8 0.3
Supplements: Zinc 0.3 0.3 2.6 -0.7 -0.5 -0.3 0.3 -0.2 -0.8 -0.1 -0.4 -0.8 -1.6 -0.7 -0.4 -0.4 -0.3 0.1 -0.6 -0.5 -0.3 -0.7 -0.4 -1.5 -0.7 0.1 -0.6 -0.3 -0.5 -0.0 -0.1 -1.1 0.0 -0.5 -0.6 0.1 -0.5 -0.3 0.4 -0.6 -0.4 -0.4 -0.7 -0.0 -0.7 -0.1 -0.1 -0.9
Medication: Co-codamol 0.1 0.1 0.9 -0.2 0.1 -0.1 0.3 0.1 -0.3 0.0 0.2 0.3 0.5 0.6 0.4 0.4 0.4 -0.0 -0.0 0.3 0.2 0.1 0.4 0.0 -0.0 0.1 -0.0 0.2 0.4 0.5 0.4 -0.5 0.0 0.4 -0.0 0.4 0.7 0.5 0.7 0.1 0.7 0.2 -0.0 1.0 -0.0 -0.4 0.5 -0.3
Medication: Metformin 0.1 0.1 1.9 -0.0 -0.3 -0.1 -0.3 -0.2 0.1 -0.2 -0.6 -0.1 -0.1 -1.4 -0.5 -0.4 -0.4 0.1 -0.1 -0.3 0.1 -0.3 -0.4 -0.0 -0.0 -0.2 -0.1 -0.2 -0.4 -0.5 -0.6 0.3 -0.1 -0.4 -0.2 -0.6 -0.0 -0.5 -0.5 -0.3 -0.2 -0.3 -0.2 -0.4 -0.1 -0.5 -0.5 -0.0
Diabetes (father) 0.2 0.2 1.0 -0.6 -0.5 -0.4 0.4 -0.3 -0.6 -0.3 -0.3 -0.3 -0.3 -0.4 -0.3 -0.3 -0.4 -0.4 -0.6 -0.4 -0.2 -0.7 -0.3 -1.0 -0.7 -0.8 -0.5 -0.6 -0.3 -0.1 -0.2 -0.6 -0.4 -0.5 -0.5 -0.2 -0.1 -0.3 -0.2 -0.5 0.6 -0.4 -0.5 -0.2 -0.6 -0.8 -0.2 -0.9
Diabetes (mother) 4.3 5.4 9.9 2.7 2.4 2.7 2.3 2.6 2.8 2.9 1.8 2.5 2.0 2.0 1.9 1.9 2.2 2.5 2.6 2.3 2.5 2.1 2.0 2.0 2.5 3.1 2.5 2.3 2.1 2.3 2.0 2.8 2.7 1.9 2.4 2.0 2.7 1.9 2.2 2.4 1.8 2.2 2.6 2.1 2.5 1.7 2.0 2.3
Severe depression (siblings) 1.1 1.2 3.2 1.6 1.0 1.3 1.5 1.8 1.6 0.3 0.2 0.8 0.9 0.8 0.4 0.5 0.9 1.6 1.6 1.0 1.1 0.8 0.6 1.1 1.7 1.5 1.5 1.2 0.6 0.9 0.5 1.0 0.7 0.2 1.2 0.5 1.0 0.5 0.5 1.2 0.8 1.0 1.5 0.9 1.7 1.5 0.5 1.2
Pack years adult smoking proportion 0.1 0.2 2.0 -0.4 -0.2 -0.1 -1.4 -0.9 -0.3 0.3 -0.1 -0.3 -0.8 -0.9 -0.0 -0.1 0.0 -0.4 -0.6 -0.0 -0.1 0.2 -0.1 -0.7 -0.0 -0.6 -0.5 -0.4 -0.1 -0.8 -0.1 0.5 -0.1 0.5 -0.2 -0.1 -0.4 0.0 -0.1 -0.1 -0.4 -0.3 -0.5 0.3 -0.0 -0.2 0.0 -0.1
Impedance of leg (right) 1.3 6.1 9.2 -2.5 -2.4 -2.3 -2.4 -2.6 -2.5 -2.5 -2.0 -2.5 -2.1 -2.7 -2.5 -2.5 -2.5 -3.0 -2.6 -2.6 -2.5 -2.5 -2.5 -0.9 -2.3 -2.9 -2.6 -2.6 -2.5 -2.8 -2.6 -2.1 -2.5 -1.8 -2.7 -2.8 -2.5 -2.5 -2.7 -2.5 -1.7 -2.6 -2.5 -3.0 -2.2 -1.9 -2.6 -2.5
Leg fat-free mass (left) 0.6 3.1 6.8 2.0 1.8 1.8 1.3 1.9 1.9 2.0 1.1 1.4 0.9 1.7 1.6 1.6 1.7 2.6 2.0 1.7 1.8 1.8 1.6 0.4 1.7 2.3 1.9 2.0 1.6 2.0 1.7 1.5 1.9 1.0 1.9 2.0 1.6 1.7 2.0 1.8 0.4 1.8 1.9 2.2 1.6 1.9 1.7 1.8
Trunk fat percentage 0.1 0.3 4.9 -0.2 -0.4 -0.3 -0.0 -0.1 -0.3 -0.8 -0.7 -0.4 -0.4 -0.3 -0.6 -0.5 -0.5 0.0 -0.1 -0.4 -0.4 -0.4 -0.5 -2.2 -0.4 0.1 -0.2 -0.2 -0.5 -0.0 -0.4 -0.6 0.1 -0.8 -0.3 -0.4 -0.2 -0.5 -0.4 -0.3 -0.3 -0.3 -0.1 -0.1 -0.4 0.2 -0.3 -0.4
Hand grip strength (right) 0.1 0.3 3.0 -0.5 -0.4 -0.8 -1.0 -0.5 -0.6 -0.1 -0.7 -0.6 -0.9 0.0 -0.4 -0.4 -0.3 0.2 -0.5 -0.4 -0.3 -0.3 -0.4 -0.9 -0.3 0.1 -0.5 0.1 -0.5 -0.3 -0.4 -0.2 -0.8 -0.5 -0.4 0.4 -0.7 -0.4 0.1 -0.4 -1.7 -0.5 -0.5 0.0 -0.4 0.0 -0.4 -0.1
Townsend deprivation index at recruitment 0.1 0.1 0.7 0.4 0.1 0.4 0.8 0.3 0.4 0.1 -0.3 -0.4 -0.8 -0.5 -0.3 -0.3 -0.1 0.7 0.4 -0.1 0.3 -0.1 -0.2 -0.3 0.4 0.7 0.3 0.7 -0.4 -0.1 -0.3 0.0 -0.0 -0.2 0.1 -0.5 -0.5 -0.3 -0.3 0.0 -0.5 0.0 0.2 -0.6 0.4 0.2 -0.3 0.3
Current tobacco smoking 0.6 0.9 6.5 0.4 -0.3 -0.1 -2.4 -1.0 0.5 0.4 -1.0 0.2 0.2 -0.3 -1.0 -1.0 -0.6 -0.4 -0.2 -0.4 -0.5 0.0 -0.9 2.6 0.6 -0.1 -0.4 -0.8 -0.6 -2.0 -1.3 2.0 -0.5 -0.1 -0.2 -1.0 -0.3 -1.0 -1.5 -0.1 -1.8 -0.7 -0.0 -0.9 0.5 -0.7 -1.3 0.6
Average weekly fortified wine intake 0.9 1.0 2.1 -1.3 -1.2 -1.1 -0.4 -1.1 -1.4 -1.3 -0.7 -1.2 -0.6 -0.9 -0.7 -0.8 -1.0 -1.4 -1.1 -1.0 -1.1 -1.0 -0.9 -1.0 -1.3 -1.2 -1.1 -0.8 -0.9 -0.8 -0.8 -1.5 -0.8 -0.9 -1.0 -1.0 -1.1 -0.8 -1.1 -1.1 -0.3 -0.9 -1.1 -0.8 -1.2 -1.0 -0.8 -1.1
Maternal smoking around birth 0.4 0.6 2.0 0.9 0.8 0.9 0.5 0.9 0.9 1.2 0.6 0.7 1.1 1.1 0.5 0.5 0.7 1.0 0.8 0.6 0.4 0.7 0.6 1.4 0.9 0.5 0.7 0.7 0.5 0.7 0.5 1.1 0.6 0.8 0.7 0.8 0.7 0.5 0.9 0.7 -0.5 0.6 0.8 0.5 0.9 1.1 0.6 0.8
Fed-up feelings 1.7 3.1 5.4 -1.6 -1.9 -1.6 0.0 -0.9 -1.5 -1.7 -2.1 -1.7 -1.6 -1.7 -2.0 -2.0 -2.1 -1.6 -1.4 -2.0 -1.6 -2.3 -1.9 -1.7 -1.8 -1.2 -1.5 -1.8 -1.9 -1.4 -1.9 -1.8 -1.6 -2.3 -1.9 -2.3 -1.1 -2.1 -1.8 -2.0 -0.2 -1.8 -1.4 -2.2 -1.8 -1.8 -2.0 -2.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 2.5 0.7 0.5 0.8 1.6 1.2 0.8 0.8 0.3 0.0 0.1 -0.0 0.3 0.4 0.4 0.7 0.8 0.5 0.9 0.1 0.5 -0.0 0.5 0.4 0.8 0.9 0.2 1.0 0.4 0.1 0.6 -0.1 0.4 0.2 0.8 0.4 0.7 0.5 1.3 0.5 0.8 0.6 0.6 0.7 0.6 0.0
Relative age voice broke 0.3 0.5 2.1 0.5 0.6 0.4 0.3 0.2 0.7 0.5 0.9 1.0 1.3 0.7 0.8 0.8 0.6 0.2 0.5 0.8 0.5 0.7 0.8 0.2 0.1 0.5 0.5 0.3 0.9 0.7 0.9 1.0 0.6 0.8 0.7 0.6 1.0 0.9 0.5 0.7 1.4 0.7 0.5 0.8 0.1 -0.2 0.9 0.7
Taking other prescription medications 1.3 2.0 4.6 -1.4 -1.4 -1.7 -0.0 -1.0 -1.2 -0.8 -1.5 -1.9 -1.9 -2.2 -1.5 -1.5 -1.5 -1.2 -1.3 -1.5 -1.3 -1.7 -1.4 -2.0 -1.6 -1.1 -1.3 -1.2 -1.6 -0.6 -1.3 -1.2 -1.2 -1.8 -1.6 -1.6 -1.4 -1.4 -0.9 -1.5 -0.7 -1.4 -1.4 -1.5 -1.7 -1.5 -1.3 -1.6
Age when periods started (menarche) 0.1 0.2 1.4 -0.2 -0.3 -0.2 -0.1 -0.3 -0.1 -0.2 -0.2 -0.0 -0.7 -0.5 -0.3 -0.3 -0.4 -0.7 -0.3 -0.2 -0.4 -0.4 -0.3 -0.5 -0.5 -1.2 -0.2 -0.7 -0.2 -0.5 -0.3 0.1 -0.4 -0.3 -0.2 -0.6 -0.1 -0.3 -0.8 -0.2 0.9 -0.3 -0.2 -0.2 -0.4 -0.5 -0.3 -0.3
Bilateral oophorectomy (both ovaries removed) 2.1 2.4 3.8 -1.4 -1.6 -1.9 -1.7 -1.6 -1.3 -1.1 -1.7 -1.6 -1.3 -1.4 -1.8 -1.7 -1.6 -1.6 -1.5 -1.5 -1.7 -1.5 -1.7 -0.8 -1.3 -1.5 -1.6 -1.9 -1.7 -2.0 -1.7 -0.7 -1.7 -1.6 -1.6 -1.6 -1.4 -1.7 -1.8 -1.4 -1.1 -1.7 -1.3 -1.3 -1.2 -1.4 -1.7 -1.4
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 3.2 0.7 1.1 0.4 -0.9 -0.0 0.8 0.9 1.3 0.8 0.5 -0.1 1.1 1.1 1.2 0.4 0.5 1.1 1.0 1.3 1.1 0.2 0.9 -0.0 0.5 0.3 1.1 0.7 0.9 1.8 0.7 0.9 0.9 1.2 0.5 1.1 0.8 1.1 -0.2 0.8 0.5 1.1 0.9 1.2 1.1 1.3
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 1.3 0.5 0.4 0.2 0.1 0.2 0.7 0.2 0.2 0.2 -0.0 -0.5 0.4 0.4 0.4 0.3 0.4 0.5 0.6 0.4 0.4 0.5 0.5 0.6 0.3 0.4 0.3 0.2 0.4 1.1 0.1 0.3 0.4 0.3 0.4 0.4 0.3 0.5 0.6 0.4 0.4 0.4 0.5 0.0 0.5 0.5
Qualifications: CSEs or equivalent 0.1 0.1 0.7 0.1 0.2 0.4 0.4 0.4 0.2 0.4 0.1 -0.0 -0.3 0.5 0.1 0.1 0.3 0.5 0.1 0.2 0.3 0.1 0.2 0.2 0.1 0.1 0.1 0.8 0.0 0.5 0.2 0.1 0.4 0.3 0.2 0.5 0.1 0.1 0.8 0.1 -0.4 0.2 0.2 -0.0 0.0 0.3 0.2 0.1
Serious illness, injury or assault to yourself 1.2 1.5 9.4 -0.8 -0.9 -0.9 -2.2 -1.7 -0.8 -0.5 -1.4 -1.5 -1.6 -1.7 -1.4 -1.4 -0.9 -0.6 -1.2 -1.0 -1.0 -0.7 -1.3 -0.4 -0.3 -0.9 -1.2 -0.9 -1.5 -1.9 -1.4 0.4 -0.7 -0.9 -1.1 -0.6 -1.6 -1.3 -1.0 -0.8 -3.1 -1.3 -1.1 -1.1 -0.4 0.2 -1.3 -0.4
High blood pressure 0.5 1.5 11.0 -1.1 -1.1 -1.1 1.3 -0.2 -1.1 -0.6 -0.7 -1.4 -1.8 -1.5 -0.6 -0.7 -1.1 -0.9 -0.8 -1.0 -0.6 -1.4 -0.7 -3.3 -1.8 -0.8 -0.7 -0.8 -0.9 0.2 -0.4 -2.1 -1.1 -1.5 -1.1 -1.3 -0.9 -0.7 -0.7 -1.3 1.1 -0.8 -0.8 -0.8 -1.7 -1.9 -0.7 -1.6
Hayfever, allergic rhinitis or eczema 0.6 1.3 4.0 0.9 1.1 1.2 1.3 1.3 0.8 0.3 1.2 1.3 1.6 0.9 1.4 1.4 1.0 0.7 1.2 1.0 1.0 1.0 1.3 0.4 0.5 1.0 1.3 1.0 1.3 1.3 1.4 -0.1 0.7 1.5 1.1 0.8 1.6 1.4 1.0 0.9 2.0 1.4 1.2 0.9 0.6 0.4 1.2 0.7
Multivitamins +/- minerals 1.1 1.3 2.9 -1.0 -1.0 -1.4 -1.4 -1.4 -0.9 -0.4 -1.0 -1.0 -1.2 -1.2 -1.3 -1.3 -1.1 -1.2 -1.3 -1.1 -0.9 -1.1 -1.2 -0.3 -0.9 -0.9 -1.3 -1.2 -1.2 -1.3 -1.3 0.2 -1.5 -0.7 -1.3 -1.1 -1.2 -1.3 -0.9 -1.2 -1.7 -1.3 -1.2 -1.3 -1.0 -1.4 -1.3 -0.9
Stomach or abdominal pain in last month 1.3 1.7 4.3 -0.8 -1.2 -1.0 -0.1 -0.5 -0.7 -0.8 -1.7 -1.2 -0.3 -0.2 -1.9 -1.8 -1.5 -1.1 -0.8 -1.4 -1.4 -1.7 -1.7 -1.0 -0.6 -1.0 -0.9 -1.4 -1.6 -1.1 -1.8 -0.8 -1.3 -2.0 -1.4 -1.9 -0.8 -1.8 -1.5 -1.2 -0.8 -1.3 -0.6 -2.1 -0.5 -1.2 -1.9 -1.3
Supplements: Glucosamine 0.1 0.1 0.4 -0.1 0.2 0.1 -0.0 -0.3 -0.1 0.0 0.6 -0.2 -0.6 0.1 0.4 0.4 0.4 0.2 -0.1 0.3 0.2 0.3 0.4 0.2 0.1 0.0 -0.0 0.4 0.2 0.4 0.4 -0.3 0.4 0.1 0.2 0.4 -0.4 0.4 0.4 0.2 -0.4 0.2 -0.1 0.2 0.0 0.6 0.5 0.3
Diverticular disease/diverticulitis (self-reported) 0.4 0.4 3.3 0.9 0.5 0.9 0.4 0.8 1.1 0.6 -0.0 1.0 1.8 0.8 -0.0 0.1 0.2 0.6 0.8 0.4 0.5 0.3 0.1 0.7 0.5 0.0 0.7 0.3 0.3 0.3 0.1 1.4 0.7 0.4 0.7 0.4 1.2 0.0 0.2 0.6 0.6 0.4 1.2 0.1 0.5 0.0 -0.0 0.6
Medication: Atenolol 0.5 0.6 3.1 -0.8 -0.9 -0.7 -0.3 -0.9 -0.7 -0.6 -0.7 -0.9 -1.8 -1.1 -0.5 -0.5 -0.6 -0.7 -0.8 -0.6 -0.4 -0.7 -0.5 -1.6 -1.1 -0.4 -0.8 -0.5 -0.7 -0.3 -0.3 -0.7 -0.6 -1.1 -0.7 -0.3 -0.8 -0.4 -0.4 -0.6 0.0 -0.6 -0.9 -0.1 -1.1 -0.9 -0.3 -0.7
Medication: Levothyroxine sodium 0.0 0.1 0.8 0.1 -0.1 -0.0 -0.5 -0.4 0.2 0.4 -0.2 -0.4 -0.4 -0.9 -0.2 -0.2 0.1 0.3 -0.1 0.1 0.1 0.1 -0.1 0.4 0.2 0.1 -0.2 0.3 -0.3 -0.2 -0.2 0.7 0.1 0.1 -0.1 0.2 -0.3 -0.1 0.1 0.2 -0.6 -0.2 -0.1 0.3 0.2 0.4 -0.0 0.1
Sitting height 0.1 0.4 4.4 0.4 0.2 0.0 -0.4 0.2 0.5 0.5 -0.6 -0.7 -0.8 -0.8 -0.4 -0.3 -0.0 1.0 0.2 -0.1 0.2 0.1 -0.2 1.8 0.6 -0.1 0.0 0.3 -0.5 0.0 -0.5 0.8 0.2 -0.3 0.0 0.2 -0.5 -0.3 0.3 0.1 -2.1 -0.1 0.2 -0.0 0.5 1.2 -0.3 0.4
Chronic bronchitis/emphysema (father) 1.2 1.4 3.8 1.1 1.1 1.6 1.0 1.1 1.2 2.0 1.0 0.8 -0.1 -0.0 0.9 0.9 1.2 1.6 1.0 1.2 1.5 0.9 1.0 1.8 1.0 1.1 1.0 1.3 0.9 1.3 1.0 1.3 1.2 1.1 1.0 1.7 1.0 1.0 1.7 1.2 0.4 1.0 0.9 1.9 0.9 1.8 1.4 1.0
High blood pressure (mother) 0.7 1.0 3.3 -0.9 -0.8 -0.9 0.5 -0.4 -0.7 -0.1 -0.8 -1.5 -1.8 -1.0 -0.9 -0.9 -1.1 -0.7 -0.8 -1.0 -0.7 -1.4 -0.8 -1.7 -1.4 -0.9 -0.8 -0.6 -1.2 0.0 -0.6 -0.9 -1.2 -1.6 -1.1 -1.2 -1.2 -0.9 -0.4 -1.1 0.1 -0.9 -1.0 -1.1 -1.4 -1.0 -0.7 -1.3
Body mass index (BMI) 0.3 1.5 3.2 1.2 1.1 1.1 0.9 1.2 1.1 1.0 0.9 1.0 0.5 1.2 1.1 1.1 1.2 1.8 1.4 1.2 1.1 1.3 1.1 -1.6 1.1 1.6 1.3 1.6 1.1 1.4 1.3 0.7 1.4 0.6 1.3 1.5 1.1 1.2 1.3 1.3 0.4 1.3 1.3 1.7 1.1 1.1 1.3 1.3
Impedance of leg (left) 1.0 4.6 7.5 -2.1 -2.0 -2.0 -2.1 -2.3 -2.0 -2.2 -1.8 -2.1 -1.7 -2.4 -2.2 -2.3 -2.2 -2.5 -2.3 -2.2 -2.2 -2.2 -2.2 -0.3 -1.9 -2.5 -2.2 -2.3 -2.2 -2.5 -2.4 -1.5 -2.3 -1.5 -2.4 -2.5 -2.1 -2.3 -2.4 -2.2 -1.6 -2.3 -2.1 -2.7 -1.8 -1.6 -2.4 -2.1
Leg predicted mass (left) 0.6 3.2 6.9 2.0 1.8 1.8 1.4 1.9 1.9 2.1 1.2 1.4 1.0 1.7 1.6 1.6 1.7 2.6 2.0 1.8 1.8 1.8 1.7 0.4 1.7 2.4 1.9 2.1 1.6 2.0 1.8 1.5 2.0 1.0 1.9 2.0 1.6 1.7 2.0 1.8 0.4 1.8 2.0 2.2 1.6 1.9 1.7 1.9
Trunk fat mass 0.0 0.2 2.7 0.4 0.1 0.2 0.2 0.4 0.3 -0.1 -0.3 -0.0 -0.3 0.1 -0.1 -0.1 0.0 0.8 0.5 0.1 0.1 0.2 -0.1 -1.6 0.2 0.8 0.3 0.4 -0.0 0.4 0.1 -0.1 0.6 -0.5 0.2 0.2 0.2 0.0 0.1 0.3 -0.4 0.2 0.4 0.5 0.2 0.7 0.1 0.3
Waist circumference 0.0 0.1 2.3 0.3 0.2 0.3 0.3 0.3 0.2 0.0 0.0 0.3 -0.3 0.3 0.2 0.2 0.2 0.5 0.4 0.2 0.2 0.3 0.2 -1.5 0.2 0.4 0.4 0.4 0.3 0.4 0.4 -0.3 0.5 -0.1 0.3 0.1 0.3 0.3 0.2 0.2 0.1 0.3 0.4 0.5 0.3 0.1 0.3 0.2
Number of incorrect matches in round 0.3 0.5 3.9 0.7 0.7 0.7 -1.1 -0.1 0.8 0.8 0.6 0.8 1.1 0.9 0.5 0.5 0.6 0.2 0.5 0.7 0.1 1.0 0.5 2.0 1.0 0.2 0.5 0.1 0.6 -0.3 0.4 1.4 0.6 0.9 0.7 0.4 0.5 0.5 -0.1 0.8 -0.1 0.5 0.6 0.5 1.0 0.6 0.4 1.2
Past tobacco smoking 2.5 4.6 8.8 -2.5 -2.3 -2.3 -0.8 -1.9 -2.5 -2.0 -2.0 -2.3 -1.8 -1.2 -2.1 -2.1 -2.2 -1.9 -2.3 -2.3 -2.5 -2.4 -2.1 -3.0 -2.8 -2.4 -2.3 -2.1 -2.1 -1.5 -1.8 -2.6 -1.8 -2.0 -2.2 -1.8 -2.1 -2.0 -1.7 -2.4 -0.9 -2.2 -2.4 -1.7 -2.8 -2.4 -1.9 -2.5
Alcohol usually taken with meals 0.2 0.3 2.1 -0.3 -0.1 0.0 1.4 0.7 -0.4 -0.2 0.2 -0.2 -0.3 0.4 0.3 0.3 -0.1 -0.1 -0.0 -0.2 0.3 -0.4 0.3 -1.0 -0.8 -0.0 0.1 0.2 0.1 1.1 0.5 -1.3 -0.2 -0.2 -0.2 0.1 0.1 0.2 0.8 -0.4 0.8 0.2 0.1 -0.1 -0.8 -0.5 0.2 -0.8
Nervous feelings 1.6 3.0 6.3 -2.0 -1.9 -1.6 0.5 -1.0 -2.0 -2.2 -1.8 -1.7 -1.3 -1.2 -1.7 -1.7 -1.8 -1.7 -1.7 -1.8 -1.6 -2.3 -1.7 -1.8 -2.2 -1.8 -1.7 -1.6 -1.8 -0.8 -1.5 -2.5 -1.8 -1.9 -1.9 -1.5 -1.5 -1.7 -1.2 -2.0 -0.2 -1.7 -1.8 -1.5 -2.2 -1.7 -1.4 -2.3
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 1.8 -0.2 -0.7 -0.4 0.3 -0.1 0.0 -0.2 -1.2 -0.9 -0.6 -0.8 -1.3 -1.2 -1.0 -0.3 -0.3 -0.7 -0.8 -1.1 -1.1 1.2 -0.3 -0.3 -0.5 -0.5 -1.2 -0.8 -1.3 0.2 -1.0 -1.1 -0.8 -1.0 -0.4 -1.3 -0.9 -0.6 -0.3 -0.8 -0.3 -0.9 -0.3 -0.2 -1.1 -0.7
Hearing difficulty/problems with background noise 0.1 0.1 1.0 0.5 0.3 0.7 -0.1 0.3 0.5 0.0 0.0 0.5 -0.1 -0.6 -0.0 0.0 0.2 0.6 0.4 0.3 0.6 0.3 0.0 1.0 0.6 0.2 0.3 0.1 0.2 -0.1 -0.1 0.8 0.2 0.3 0.4 0.3 0.4 -0.0 0.1 0.4 -0.1 0.2 0.3 0.2 0.6 0.4 -0.0 0.5
Hair/balding pattern: Pattern 2 0.6 0.8 4.6 -0.8 -0.6 -1.1 -1.8 -1.2 -0.8 -0.2 -0.5 -0.4 -0.6 -2.1 -0.6 -0.7 -0.6 -1.4 -0.9 -0.7 -0.6 -0.5 -0.7 -0.6 -0.5 -0.7 -1.0 -1.2 -0.5 -1.0 -0.9 0.3 -1.0 -0.2 -0.9 -0.8 -0.6 -0.7 -0.8 -0.7 -1.2 -0.8 -0.8 -0.9 -0.5 -1.0 -0.9 -0.5
Had menopause 0.6 0.8 2.0 -1.0 -1.0 -0.8 -1.0 -1.0 -1.0 -1.1 -0.7 -0.2 -0.1 -0.9 -0.7 -0.8 -0.9 -1.1 -1.0 -0.9 -0.8 -0.8 -0.8 -0.4 -1.1 -1.4 -1.0 -1.2 -0.6 -1.0 -0.8 -0.5 -0.9 -0.5 -0.8 -0.9 -0.7 -0.7 -1.0 -0.9 -0.2 -0.9 -1.0 -0.8 -1.1 -1.3 -0.7 -0.9
Had other major operations 1.7 2.0 4.7 1.4 1.6 1.3 0.9 1.3 1.3 1.2 1.6 1.3 1.1 1.3 1.6 1.6 1.6 1.4 1.4 1.6 1.3 1.6 1.5 0.6 1.6 0.9 1.5 1.4 1.5 1.3 1.5 0.9 1.4 1.8 1.5 1.7 1.0 1.5 1.5 1.6 0.5 1.5 1.4 1.2 1.5 2.2 1.6 1.8
Forced vital capacity (FVC) 0.4 1.5 3.3 1.5 1.2 1.2 0.9 1.4 1.4 0.6 0.8 1.2 1.4 1.0 0.9 0.9 1.1 1.8 1.5 1.1 1.0 1.2 0.9 1.7 1.6 1.4 1.4 1.5 1.0 1.0 0.7 1.0 1.1 0.9 1.4 1.4 1.0 0.8 1.0 1.2 -0.5 1.2 1.5 1.0 1.4 1.4 0.8 1.7
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.3 1.0 0.2 0.6 -0.3 -1.0 -0.4 0.2 0.3 0.9 0.2 0.2 -0.5 0.6 0.5 0.6 0.2 0.0 0.5 0.4 0.7 0.5 -0.5 0.5 -0.4 0.0 -0.1 0.5 0.2 0.3 0.9 0.2 0.5 0.4 0.9 0.0 0.6 0.4 0.5 -0.7 0.3 0.1 0.5 0.5 0.8 0.6 0.8
Ever unenthusiastic/disinterested for a whole week 0.1 0.1 1.0 0.4 0.4 0.5 -0.3 0.1 0.4 0.1 0.1 0.3 0.1 0.1 0.2 0.2 0.4 0.3 0.2 0.4 0.3 0.4 0.2 0.9 0.5 0.1 0.2 0.3 0.2 0.0 0.2 0.6 0.3 0.2 0.3 0.5 0.0 0.3 0.4 0.4 -0.3 0.3 0.2 0.2 0.5 1.0 0.3 0.4
Qualifications: None of the above 0.5 1.1 2.7 1.1 0.9 1.2 0.6 0.8 1.0 0.6 0.8 1.0 0.3 0.4 0.9 0.9 1.1 1.2 1.0 1.1 0.9 1.2 0.9 0.5 1.4 1.2 1.0 1.3 1.0 0.5 1.0 0.8 1.6 0.9 1.1 1.0 1.0 1.0 0.7 1.2 0.5 1.0 0.7 1.4 1.4 1.6 1.2 1.1
Financial difficulties in last 2 years 0.2 0.2 2.0 0.5 0.4 0.5 -0.5 0.1 0.6 1.1 0.1 0.5 0.7 0.5 -0.0 0.0 0.4 0.5 0.3 0.5 0.3 0.3 0.1 -0.1 0.8 0.4 0.2 0.1 0.2 -0.3 0.0 1.4 0.2 0.4 0.2 0.4 0.6 0.1 0.2 0.5 0.3 0.2 0.3 0.6 0.9 0.6 0.2 0.3
Mouth/teeth dental problems 0.0 0.1 0.5 -0.2 -0.0 0.2 0.6 -0.1 -0.1 -0.2 -0.0 -0.6 -0.7 -0.3 -0.1 -0.1 -0.1 0.2 -0.2 -0.1 0.1 -0.2 -0.0 0.2 -0.4 -0.0 -0.1 0.5 -0.3 0.4 -0.0 -0.3 -0.1 0.1 -0.1 0.1 -0.5 -0.1 0.2 -0.2 -0.5 -0.1 -0.3 -0.3 -0.4 0.1 0.0 -0.0
Heart attack 0.5 0.6 1.9 -0.8 -0.8 -0.8 -0.5 -0.9 -0.6 -0.2 -0.6 -1.1 -1.4 -1.4 -0.7 -0.8 -0.6 -0.3 -0.9 -0.7 -0.6 -0.8 -0.7 -0.9 -0.8 -0.4 -0.9 -0.8 -0.9 -0.5 -0.6 -0.0 -0.7 -1.0 -0.7 -0.2 -1.1 -0.7 -0.3 -0.6 -0.9 -0.8 -1.1 -0.3 -0.9 -0.5 -0.4 -0.6
Allergy 0.3 0.6 2.5 -0.7 -0.8 -0.8 -0.4 -0.7 -0.6 -0.1 -0.8 -1.0 -1.6 -1.0 -1.0 -1.0 -0.7 -0.6 -0.8 -0.7 -0.6 -0.8 -0.9 -0.7 -0.4 -0.9 -0.8 -0.7 -0.9 -0.7 -0.8 -0.1 -0.6 -1.2 -0.8 -0.6 -1.0 -0.9 -0.7 -0.6 -0.8 -0.9 -0.9 -0.5 -0.4 -0.4 -0.7 -0.6
Pain all over the body in last month 0.2 0.2 1.6 -0.3 -0.5 -0.2 0.2 -0.1 -0.5 -1.0 -0.7 -0.4 -0.5 0.4 -0.4 -0.4 -0.4 -0.1 -0.1 -0.3 -0.6 -0.5 -0.4 -1.3 -0.2 0.3 -0.2 -0.2 -0.4 -0.3 -0.4 -1.1 -0.2 -0.7 -0.4 -0.5 -0.1 -0.4 -0.7 -0.3 0.3 -0.3 -0.2 -0.2 -0.0 -0.2 -0.4 -0.4
Diabetes (self-reported) 0.5 0.7 2.2 -0.6 -0.9 -0.6 -0.4 -0.6 -0.5 -0.0 -1.1 -0.5 -0.5 -1.2 -1.0 -1.0 -1.1 -0.6 -0.7 -0.9 -0.5 -1.0 -0.9 -0.1 -0.9 -0.8 -0.7 -0.9 -0.9 -0.9 -1.1 -0.3 -0.7 -1.0 -0.8 -1.3 -0.4 -1.0 -0.9 -0.9 -0.0 -0.9 -0.6 -0.9 -0.9 -1.5 -1.1 -0.9
Hayfever/allergic rhinitis (self-reported) 0.1 0.2 1.2 -0.3 -0.2 -0.1 1.1 0.3 -0.3 -0.2 0.1 -0.2 0.3 0.5 0.1 0.1 -0.2 -0.5 -0.1 -0.3 -0.2 -0.5 0.1 -0.5 -0.7 -0.2 0.0 -0.2 0.0 0.5 0.1 -1.0 -0.8 0.4 -0.3 -0.3 0.2 0.1 0.2 -0.4 1.0 0.0 -0.1 0.1 -0.6 -1.0 0.1 -0.8
Medication: Ramipril 0.2 0.2 1.8 0.2 0.3 0.2 0.3 0.2 0.3 0.8 0.6 -0.5 -1.3 -1.2 0.4 0.4 0.4 0.7 0.1 0.4 0.7 0.3 0.4 -0.3 -0.0 0.0 0.1 0.6 0.1 0.6 0.5 0.4 0.3 0.1 0.2 0.8 -0.3 0.4 0.7 0.3 0.1 0.3 -0.0 0.7 -0.1 0.5 0.6 0.3
Medication: Simvastatin 1.2 1.8 4.5 -1.5 -1.4 -1.6 -0.1 -1.0 -1.5 -1.2 -0.9 -1.3 -1.2 -1.3 -1.0 -1.0 -1.4 -1.7 -1.3 -1.4 -1.0 -1.5 -1.1 -2.1 -1.8 -1.1 -1.2 -1.3 -1.1 -0.8 -0.8 -1.9 -1.4 -1.5 -1.4 -1.7 -0.9 -1.0 -1.2 -1.5 0.8 -1.2 -1.3 -1.2 -1.8 -1.9 -1.0 -1.9
Fluid intelligence score 0.5 1.0 6.9 -1.1 -0.8 -0.8 1.9 0.2 -1.0 -0.3 -0.3 -1.3 -0.9 -0.3 -0.5 -0.5 -0.8 -0.5 -0.7 -0.9 -0.5 -1.4 -0.5 -2.6 -1.4 -0.9 -0.6 -0.3 -0.8 0.8 -0.3 -2.0 -1.1 -1.4 -1.0 -0.8 -0.8 -0.5 0.2 -1.1 0.8 -0.6 -0.9 -0.6 -1.5 -1.0 -0.3 -1.6
Illnesses of siblings 1.5 2.1 6.9 1.9 1.3 1.6 1.3 2.0 1.7 0.8 0.8 1.5 2.2 2.6 1.0 1.1 1.2 1.8 1.9 1.2 0.9 1.3 1.1 1.8 1.9 1.6 1.8 1.3 1.2 0.6 0.9 0.9 1.5 1.3 1.6 0.9 1.7 1.0 0.7 1.5 1.2 1.4 2.1 0.9 1.9 1.2 0.7 1.5
Neuroticism score 2.2 4.5 7.0 -2.0 -2.2 -2.0 -0.4 -1.3 -1.9 -2.5 -2.6 -2.1 -1.5 -2.2 -2.5 -2.5 -2.4 -2.1 -1.9 -2.3 -2.2 -2.6 -2.4 -1.6 -1.9 -1.8 -2.0 -2.1 -2.4 -1.8 -2.5 -1.8 -2.2 -2.6 -2.3 -2.3 -1.7 -2.5 -2.0 -2.3 -1.2 -2.2 -1.9 -2.2 -1.9 -1.7 -2.3 -2.5
Weight 0.3 1.6 4.9 1.5 1.2 1.4 1.0 1.4 1.4 1.3 0.7 0.9 0.4 1.0 1.0 1.0 1.2 2.2 1.5 1.2 1.2 1.3 1.1 -0.5 1.3 1.9 1.4 1.6 1.0 1.5 1.2 1.0 1.6 0.6 1.4 1.5 1.0 1.1 1.5 1.3 -0.1 1.3 1.4 1.7 1.2 1.5 1.2 1.4
Impedance of arm (right) 0.9 4.4 8.9 -2.3 -2.2 -1.9 -0.8 -1.8 -2.2 -2.4 -1.9 -1.8 -0.8 -1.8 -2.0 -2.0 -2.4 -3.0 -2.1 -2.3 -2.0 -2.4 -2.0 -1.3 -2.7 -2.0 -2.1 -2.6 -1.9 -1.7 -1.9 -2.4 -1.8 -1.7 -2.3 -2.6 -1.4 -2.0 -2.2 -2.3 -0.0 -2.0 -1.9 -2.6 -2.6 -2.3 -2.1 -2.6
Arm fat percentage (right) 0.1 0.4 4.4 0.6 0.4 0.5 0.7 0.7 0.5 0.1 0.2 0.5 0.4 0.8 0.5 0.5 0.4 0.7 0.8 0.5 0.4 0.5 0.5 -2.1 0.2 1.1 0.7 0.7 0.5 0.9 0.7 -0.1 0.9 0.0 0.6 0.5 0.7 0.6 0.5 0.6 0.7 0.6 0.8 0.8 0.2 0.4 0.6 0.5
Trunk fat-free mass 0.7 3.8 9.5 2.3 2.0 2.2 1.3 2.1 2.2 2.2 1.4 1.5 0.7 1.5 1.7 1.7 1.9 3.1 2.2 1.9 1.9 2.1 1.8 1.5 2.2 2.7 2.1 2.4 1.6 1.9 1.7 1.8 2.1 1.2 2.1 2.1 1.4 1.7 2.1 2.0 -0.3 1.9 2.1 2.2 2.0 2.0 1.6 2.3
Hip circumference 0.2 0.7 2.8 0.7 0.7 0.8 0.8 1.0 0.6 0.7 0.4 0.6 0.0 0.8 0.7 0.7 0.7 1.3 0.9 0.7 0.7 0.7 0.7 -1.7 0.6 1.1 0.8 0.8 0.7 1.3 0.9 0.0 1.1 0.2 0.8 1.0 0.8 0.8 1.0 0.7 0.3 0.8 0.8 1.2 0.6 0.8 0.9 0.6
Time employed in main current job 0.7 0.8 5.0 1.3 0.8 0.8 -0.6 0.8 1.1 -0.0 0.6 1.0 0.9 0.6 0.5 0.5 0.6 0.3 1.2 0.6 0.7 1.1 0.5 2.2 1.6 0.5 1.1 0.6 0.7 -0.3 0.3 0.7 0.8 0.7 0.9 -0.1 0.7 0.4 -0.5 0.9 -0.2 0.8 1.4 -0.1 1.6 1.3 -0.0 1.4
Alcohol intake versus 10 years previously 2.1 3.2 6.1 1.8 1.8 1.6 1.3 1.7 2.0 2.1 1.6 1.7 0.7 1.2 1.8 1.8 1.9 1.8 1.8 2.0 1.9 1.8 1.9 0.5 1.6 1.9 1.8 1.7 1.8 1.7 1.9 1.8 1.9 1.5 1.9 1.7 1.9 1.9 1.5 2.1 2.5 1.8 1.8 2.0 1.8 2.2 2.2 1.7
Father’s age at death 1.0 1.3 2.4 1.0 1.1 1.1 1.3 1.1 0.9 1.1 1.5 0.9 1.2 0.8 1.4 1.4 1.2 1.2 1.0 1.2 1.2 1.1 1.3 0.8 0.8 0.9 1.1 1.3 1.3 1.5 1.5 0.4 1.3 1.0 1.2 1.2 0.9 1.4 1.3 1.0 1.1 1.3 0.9 1.1 0.8 0.5 1.4 1.1
Worrier / anxious feelings 2.9 5.6 7.3 -2.5 -2.5 -2.6 -1.4 -2.0 -2.5 -2.3 -2.6 -2.5 -1.5 -2.4 -2.6 -2.6 -2.5 -2.5 -2.5 -2.5 -2.5 -2.7 -2.6 -1.3 -2.6 -2.4 -2.6 -2.5 -2.5 -1.8 -2.5 -1.9 -2.5 -2.3 -2.7 -1.9 -2.2 -2.5 -1.7 -2.6 -2.2 -2.6 -2.3 -2.1 -2.6 -2.1 -2.4 -2.6
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.1 0.8 0.4 0.3 0.3 -0.1 0.2 0.5 0.4 0.1 0.4 -0.2 -0.4 0.1 0.1 0.2 0.2 0.3 0.3 0.5 0.3 0.1 0.8 0.4 0.4 0.2 0.2 0.1 0.2 0.1 0.9 0.4 -0.1 0.2 0.2 0.5 0.1 0.3 0.4 -0.1 0.2 0.3 0.5 0.4 0.9 0.2 0.3
Falls in the last year 0.1 0.2 1.1 0.6 0.3 0.4 -0.1 0.3 0.6 -0.1 -0.0 0.5 0.3 -0.3 0.2 0.2 0.3 0.4 0.6 0.4 0.3 0.5 0.2 0.4 0.8 -0.0 0.5 0.2 0.3 -0.1 0.3 0.3 0.5 -0.1 0.5 0.0 0.4 0.2 -0.3 0.6 0.5 0.4 0.7 0.1 0.9 1.0 0.2 0.5
Hair/balding pattern: Pattern 3 3.8 5.7 9.7 2.2 2.5 2.3 1.9 2.1 2.2 2.7 2.6 1.8 1.6 2.5 2.6 2.6 2.7 2.8 2.1 2.6 2.4 2.5 2.6 0.9 2.2 1.3 2.3 2.6 2.4 2.5 2.6 1.7 2.1 2.7 2.4 3.1 2.0 2.6 3.0 2.6 1.2 2.5 2.3 2.8 2.1 2.9 2.8 2.4
Number of live births 0.1 0.2 0.6 0.0 -0.4 0.2 0.2 -0.1 0.1 0.4 -0.7 -0.2 -0.1 0.4 -0.8 -0.7 -0.5 0.0 -0.0 -0.4 -0.5 -0.4 -0.7 0.0 0.0 0.8 -0.1 -0.1 -0.6 -0.5 -0.7 0.2 -0.4 -0.3 -0.2 -0.4 -0.4 -0.7 -0.5 -0.3 -0.7 -0.5 -0.2 -0.2 -0.1 -0.4 -0.7 -0.1
Forced expiratory volume in 1-second (FEV1) 0.3 1.1 3.7 -0.7 -1.0 -1.0 -0.6 -0.7 -0.8 -1.6 -1.3 -1.1 -0.2 -0.9 -1.4 -1.3 -1.2 -0.4 -0.7 -1.2 -1.3 -1.0 -1.3 -0.0 -0.6 -0.6 -0.8 -0.8 -1.3 -1.1 -1.5 -0.9 -1.1 -1.2 -0.9 -0.8 -1.2 -1.4 -1.2 -1.0 -1.9 -1.1 -0.7 -1.2 -0.8 -0.9 -1.5 -0.5
Pulse rate 0.4 0.7 1.9 0.7 0.7 0.7 0.7 0.9 0.6 0.1 0.8 0.5 0.5 0.1 0.8 0.8 0.8 1.4 0.8 0.8 0.6 0.9 0.7 0.9 0.8 1.2 0.8 1.3 0.7 0.9 0.9 -0.0 1.3 0.6 0.9 1.1 0.6 0.8 1.0 0.7 -0.2 0.8 0.8 1.0 0.7 1.0 0.8 0.9
Happiness 0.6 0.7 5.1 -0.7 -0.7 -0.4 1.6 0.4 -0.6 -0.6 -0.8 -0.9 -0.5 -0.2 -0.8 -0.8 -0.9 -0.0 -0.4 -0.8 -0.6 -1.3 -0.7 -2.2 -1.1 -0.6 -0.4 -0.2 -0.9 0.2 -0.5 -1.4 -0.5 -1.3 -0.8 -0.6 -0.5 -0.8 -0.1 -1.0 0.7 -0.6 -0.4 -0.7 -1.1 -1.3 -0.7 -1.3
Noisy workplace 1.0 1.2 4.5 1.6 1.2 1.1 -0.2 0.6 1.6 0.6 0.8 1.2 0.5 0.3 0.7 0.8 0.9 1.2 1.3 1.1 0.9 1.4 0.8 1.6 1.5 1.9 1.2 1.4 0.8 0.1 0.6 2.1 1.4 1.1 1.3 0.9 0.9 0.7 0.2 1.3 0.0 1.0 1.2 0.6 1.4 0.8 0.6 1.9
Qualifications: A levels/AS levels or equivalent 0.3 0.7 4.7 -1.1 -0.8 -0.9 0.6 -0.3 -1.2 -1.3 -0.4 -0.9 -0.9 -1.2 -0.2 -0.2 -0.6 -0.8 -0.7 -0.7 -0.1 -0.9 -0.3 -2.0 -1.4 -0.9 -0.7 -0.4 -0.4 0.1 -0.1 -2.2 -1.0 -0.5 -0.8 -0.6 -0.5 -0.2 -0.2 -0.8 1.1 -0.5 -0.7 -0.2 -1.3 -0.7 -0.1 -1.3
Serious illness, injury or assault of a close relative in last 2 years 1.0 1.1 2.0 1.0 1.1 0.6 0.1 0.8 1.0 1.0 1.3 1.1 0.4 -0.3 1.4 1.4 1.2 0.4 1.0 1.2 1.0 1.3 1.3 1.1 0.8 0.9 1.0 0.5 1.4 1.0 1.4 0.9 1.1 1.0 1.0 1.1 1.3 1.4 1.0 1.2 1.3 1.3 1.2 1.2 0.8 0.9 1.2 1.0
Mouth/teeth dental problems: Dentures 0.1 0.1 1.3 -0.0 -0.1 -0.3 -1.1 -0.6 -0.0 0.0 0.1 -0.0 0.5 0.2 -0.0 -0.0 0.0 -0.4 -0.2 0.1 -0.4 0.3 -0.0 -0.5 0.2 -0.6 -0.1 -0.7 0.0 -0.6 -0.1 0.3 0.0 -0.2 -0.0 -0.2 -0.1 0.0 -0.3 0.1 -0.1 -0.1 -0.1 0.1 0.2 -0.3 -0.0 0.2
Asthma 0.4 0.8 1.6 0.9 1.1 0.8 0.1 0.7 0.9 0.8 0.9 1.0 1.3 1.2 0.9 0.9 0.8 1.0 0.9 0.9 0.9 1.0 1.0 0.6 0.8 1.1 0.8 0.9 0.9 0.8 0.8 1.1 0.5 1.1 0.8 0.9 1.0 0.9 1.0 0.8 0.2 0.9 0.8 0.7 0.7 0.7 0.7 0.9
Medication: Ibuprofen (e.g. Nurofen) 0.8 1.0 2.8 1.2 1.0 0.9 0.2 1.0 1.3 1.2 0.5 1.2 0.9 0.8 0.7 0.7 0.9 1.1 1.2 1.0 1.1 1.0 0.8 1.0 1.1 1.6 1.1 1.0 0.9 0.6 0.7 1.7 0.8 0.8 1.0 0.8 1.3 0.7 0.8 1.1 0.5 0.9 1.2 0.7 1.2 1.1 0.7 1.1
Medication: Cholesterol lowering 4.5 7.0 16.0 -3.1 -2.8 -3.0 -1.0 -2.4 -3.1 -1.9 -2.2 -3.1 -3.0 -2.7 -2.2 -2.3 -2.5 -2.5 -2.9 -2.7 -2.3 -2.9 -2.3 -4.0 -3.4 -2.3 -2.8 -2.5 -2.6 -1.4 -1.9 -3.1 -2.5 -2.9 -3.0 -2.1 -2.8 -2.3 -1.6 -3.0 -1.3 -2.6 -3.1 -2.2 -3.4 -2.9 -2.0 -3.1
Depression (self-reported) 5.0 6.1 8.8 -2.6 -2.5 -2.4 -1.2 -2.1 -2.5 -1.9 -2.7 -2.6 -2.4 -2.1 -2.8 -2.8 -2.6 -2.2 -2.5 -2.6 -2.3 -2.8 -2.7 -2.3 -2.6 -2.5 -2.5 -2.2 -2.8 -2.1 -2.6 -2.1 -3.0 -2.4 -2.7 -2.3 -2.5 -2.6 -1.9 -2.7 -2.1 -2.7 -2.4 -2.3 -2.7 -2.1 -2.6 -2.8
Medication: Lansoprazole 0.5 0.5 1.4 -0.7 -0.8 -1.0 -0.7 -0.7 -0.7 -0.9 -0.9 -0.7 -0.5 -0.8 -0.6 -0.6 -0.8 -0.8 -0.6 -0.8 -0.8 -0.6 -0.7 -0.3 -0.9 -0.8 -0.6 -0.7 -0.6 -0.4 -0.7 -0.8 -1.2 -1.0 -0.6 -0.7 -0.7 -0.7 -0.9 -0.7 -0.4 -0.7 -0.5 -1.1 -0.9 -0.6 -0.7 -0.4
Prospective memory result 0.1 0.1 1.0 0.5 0.1 0.3 -0.8 -0.2 0.5 -0.2 0.1 0.2 -0.6 -0.1 -0.1 -0.0 0.0 0.2 0.3 0.2 0.3 0.4 -0.0 1.0 0.4 -0.3 0.3 0.1 0.0 -0.6 -0.1 0.7 -0.1 0.3 0.3 -0.2 -0.2 -0.1 -0.6 0.3 -0.1 0.1 0.2 -0.3 0.5 0.7 -0.0 0.6
Lung cancer (father) 2.2 2.6 4.6 1.9 1.6 1.9 1.1 1.7 1.8 1.3 1.2 1.7 1.8 1.6 1.2 1.3 1.5 1.9 1.8 1.6 1.6 1.6 1.3 1.9 2.0 1.6 1.7 1.9 1.4 1.0 1.2 1.5 2.0 1.7 1.8 1.5 1.6 1.2 1.3 1.7 0.6 1.5 1.7 1.2 2.0 2.2 1.3 1.8
Illnesses of mother 0.5 0.6 3.3 1.0 0.7 0.6 0.1 0.8 0.9 0.2 0.6 0.8 0.8 0.9 0.4 0.5 0.6 1.1 0.9 0.7 0.4 0.9 0.5 1.8 1.2 0.4 0.8 0.8 0.5 0.1 0.3 0.6 0.5 0.8 0.9 0.4 0.5 0.5 0.2 0.9 -0.1 0.7 0.9 0.4 1.1 1.3 0.3 1.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.0 0.1 0.7 0.4 0.1 0.3 0.4 0.6 0.3 -0.4 -0.3 -0.0 0.4 -0.2 -0.3 -0.2 -0.0 0.8 0.5 -0.0 -0.0 -0.0 -0.2 0.6 0.4 0.7 0.4 0.4 -0.2 0.1 -0.3 -0.2 -0.1 -0.3 0.2 0.4 0.1 -0.3 -0.0 0.1 -0.9 0.1 0.5 0.2 0.3 0.4 -0.3 0.4
Pulse wave Arterial Stiffness index 0.3 0.3 1.7 -0.6 -0.5 -0.4 0.3 -0.4 -0.6 -0.9 -0.4 -1.1 -1.3 -0.7 -0.3 -0.3 -0.3 -0.1 -0.6 -0.4 -0.7 -0.6 -0.3 0.3 -0.5 -0.7 -0.5 -0.3 -0.6 -0.0 -0.2 -1.0 -0.0 -0.6 -0.5 -0.2 -1.0 -0.3 -0.1 -0.4 -0.1 -0.4 -0.6 0.0 -0.5 0.3 -0.0 -0.7
Impedance of arm (left) 0.7 3.0 5.8 -1.9 -1.8 -1.6 -0.6 -1.5 -1.8 -2.1 -1.8 -1.6 -0.5 -1.4 -1.8 -1.8 -1.9 -2.4 -1.8 -1.9 -1.8 -2.1 -1.8 -0.5 -2.2 -1.7 -1.8 -2.2 -1.7 -1.4 -1.8 -1.7 -1.7 -1.3 -1.9 -2.1 -1.2 -1.8 -1.8 -1.9 -0.2 -1.8 -1.7 -2.1 -2.1 -1.7 -1.7 -2.1
Arm fat mass (right) 0.2 0.7 2.3 1.0 0.8 0.8 0.6 0.9 0.9 0.5 0.3 0.6 0.4 0.9 0.6 0.7 0.7 1.4 1.1 0.8 0.7 0.9 0.6 -1.2 0.8 1.5 1.0 1.1 0.7 1.0 0.8 0.4 1.2 0.1 0.9 0.9 0.8 0.7 0.8 0.9 0.1 0.9 1.1 1.2 0.8 1.0 0.7 0.9
Trunk predicted mass 0.7 3.9 9.5 2.3 2.0 2.2 1.3 2.1 2.2 2.3 1.4 1.5 0.8 1.5 1.7 1.8 1.9 3.1 2.3 1.9 2.0 2.1 1.8 1.5 2.2 2.7 2.1 2.4 1.7 1.9 1.8 1.9 2.1 1.3 2.2 2.1 1.5 1.8 2.1 2.0 -0.2 2.0 2.1 2.3 2.1 2.1 1.7 2.4
Standing height 0.0 0.4 4.5 0.8 0.4 0.8 0.3 0.7 0.8 0.7 -0.3 -0.1 -0.2 -0.3 -0.0 0.0 0.2 1.3 0.7 0.2 0.5 0.3 0.1 2.1 0.6 0.9 0.5 0.4 -0.0 0.6 -0.1 0.8 0.6 -0.0 0.4 0.4 0.1 0.0 0.6 0.4 -1.1 0.3 0.6 0.4 0.4 1.2 0.0 0.6
Length of working week for main job 3.2 3.6 5.7 1.6 2.0 1.9 1.3 1.7 1.6 1.8 1.9 2.0 1.5 1.6 2.0 2.0 2.1 2.0 1.6 2.0 2.2 1.9 2.0 1.1 1.6 2.0 1.7 2.0 2.0 1.9 2.1 1.8 2.2 2.2 1.9 2.3 1.7 2.0 2.4 1.9 0.9 1.9 1.7 2.0 1.6 2.3 2.1 1.7
Exposure to tobacco smoke at home 0.2 0.2 1.4 0.5 0.3 0.5 -0.9 -0.2 0.6 0.3 0.1 0.0 -0.6 -1.1 0.1 0.1 0.3 0.1 0.3 0.4 0.4 0.5 0.2 0.9 0.7 0.6 0.2 0.3 0.1 -0.4 0.1 1.1 -0.2 0.3 0.3 0.2 0.1 0.1 -0.2 0.6 -0.5 0.2 0.5 0.2 0.7 1.2 0.1 0.6
Breastfed as a baby 0.2 0.3 1.8 0.2 0.3 0.7 0.5 0.2 0.2 0.4 0.5 0.5 0.9 1.4 0.5 0.5 0.5 0.7 0.2 0.5 0.4 0.4 0.4 0.3 0.4 0.2 0.3 0.4 0.4 0.2 0.5 0.1 0.7 0.6 0.4 0.7 0.3 0.5 0.5 0.4 0.5 0.4 0.1 0.9 0.3 0.4 0.7 0.3
Tense / ‘highly strung’ 4.9 8.1 14.2 -2.9 -3.0 -3.1 -1.2 -2.1 -3.0 -3.8 -3.1 -3.0 -2.4 -2.7 -2.9 -2.9 -3.0 -2.9 -2.6 -3.0 -2.8 -3.2 -2.9 -2.2 -2.8 -2.6 -2.7 -2.8 -2.9 -2.4 -2.9 -3.4 -3.0 -3.3 -3.0 -3.1 -2.7 -2.9 -2.9 -3.1 -1.4 -2.8 -2.5 -2.9 -2.8 -2.7 -3.0 -3.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.4 2.1 4.1 -1.7 -1.5 -1.4 -0.2 -1.1 -1.6 -1.5 -1.6 -1.4 -1.8 -1.8 -1.4 -1.4 -1.5 -1.7 -1.5 -1.4 -1.2 -1.8 -1.4 -1.6 -1.9 -1.6 -1.5 -1.6 -1.4 -0.8 -1.2 -1.6 -1.7 -1.6 -1.7 -1.5 -1.0 -1.3 -1.0 -1.5 0.0 -1.4 -1.4 -1.2 -1.8 -1.3 -1.1 -2.0
Hair/balding pattern: Pattern 4 0.2 0.6 1.5 -0.6 -0.8 -0.9 -1.2 -0.8 -0.6 -1.0 -1.0 -0.1 0.2 -0.1 -0.8 -0.8 -0.9 -1.1 -0.6 -0.8 -0.7 -0.6 -0.8 1.0 -0.7 -0.2 -0.7 -0.9 -0.6 -1.0 -0.8 0.0 -0.5 -0.9 -0.7 -1.0 -0.3 -0.8 -1.1 -0.8 -0.7 -0.8 -0.6 -0.9 -0.7 -1.0 -0.9 -0.5
Birth weight of first child 0.4 0.7 4.2 -0.6 -0.8 -0.4 1.4 0.0 -0.7 -1.3 -0.7 -1.4 -1.5 -0.5 -0.8 -0.7 -0.8 -0.2 -0.4 -0.8 -0.9 -1.1 -0.8 -1.1 -0.6 -0.1 -0.4 0.2 -1.0 0.3 -0.5 -2.0 -0.7 -1.3 -0.7 -0.6 -1.4 -0.8 -0.3 -0.9 -0.7 -0.6 -0.8 -1.2 -0.8 -0.3 -0.6 -0.7
Peak expiratory flow (PEF) 1.3 3.1 4.8 -1.9 -1.8 -1.9 -0.8 -1.5 -2.0 -1.7 -1.6 -1.7 -0.7 -1.5 -1.8 -1.8 -1.9 -1.6 -1.8 -2.0 -1.9 -1.9 -1.8 -1.6 -1.9 -1.6 -1.8 -1.9 -1.8 -1.4 -1.9 -1.8 -1.8 -1.6 -1.9 -1.5 -1.9 -1.8 -1.4 -2.0 -2.0 -1.8 -1.7 -1.8 -2.0 -2.2 -2.0 -1.8
Pulse wave reflection index 0.5 0.6 1.9 -1.0 -0.8 -0.7 0.3 -0.6 -0.9 -0.7 -0.6 -0.8 -1.1 -0.1 -0.5 -0.5 -0.7 -1.0 -0.8 -0.8 -0.8 -1.0 -0.5 -0.9 -1.1 -0.9 -0.7 -0.9 -0.6 -0.4 -0.4 -1.4 -0.6 -0.8 -0.8 -0.8 -0.7 -0.5 -0.6 -0.8 0.8 -0.6 -0.8 -0.6 -1.0 -1.1 -0.4 -1.1
Ever highly irritable/argumentative for 2 days 0.2 0.3 0.8 -0.3 -0.4 -0.3 -0.1 -0.2 -0.3 -0.6 -0.7 -0.4 -0.7 0.3 -0.7 -0.6 -0.6 -0.3 -0.3 -0.5 -0.4 -0.6 -0.6 -0.6 -0.2 -0.6 -0.3 0.2 -0.6 -0.4 -0.6 -0.3 -0.5 -0.7 -0.4 -0.7 -0.5 -0.7 -0.7 -0.5 -0.0 -0.5 -0.2 -0.9 -0.1 -0.7 -0.8 -0.6
Loud music exposure frequency 0.2 0.2 0.8 0.1 0.2 0.3 -0.6 -0.1 0.0 -0.4 0.5 0.8 0.6 0.6 0.7 0.6 0.5 -0.0 0.1 0.5 0.4 0.7 0.6 0.2 0.3 0.2 0.2 0.3 0.7 -0.0 0.5 -0.1 0.2 0.5 0.5 0.6 0.6 0.7 0.2 0.5 0.7 0.4 0.3 0.9 0.3 0.5 0.5 0.3
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 3.3 0.0 0.3 0.4 1.4 0.9 0.0 0.3 0.6 0.3 0.7 0.2 0.6 0.6 0.3 0.2 0.4 0.3 0.8 -0.1 0.6 -0.8 -0.2 0.3 0.4 0.3 0.5 1.0 0.6 -0.9 0.0 0.5 0.2 0.2 0.6 0.6 0.6 0.2 1.8 0.5 0.5 0.2 -0.2 -0.1 0.5 -0.4
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 1.7 -0.5 -0.5 -0.1 1.0 0.5 -0.6 -0.7 -0.8 -0.3 0.5 0.2 -0.7 -0.7 -0.7 0.1 -0.1 -0.7 -0.5 -0.9 -0.7 -0.4 -0.7 0.2 -0.2 -0.2 -0.6 0.1 -0.6 -1.3 -0.4 -0.3 -0.5 -0.2 -0.2 -0.7 -0.1 -0.8 -0.3 -0.4 -0.2 -0.7 -0.8 -0.4 -0.7 -0.7
Blood clot in the leg (DVT) 0.1 0.1 0.9 0.5 0.3 0.4 -0.0 0.3 0.6 0.9 -0.3 -0.0 0.2 -0.0 -0.1 -0.1 0.1 0.5 0.4 0.1 0.2 0.1 -0.0 0.8 0.6 0.3 0.3 0.1 -0.1 -0.2 -0.2 0.9 0.3 0.2 0.2 0.0 0.1 -0.1 -0.0 0.3 -0.6 0.1 0.5 -0.3 0.6 0.4 -0.2 0.4
Medication: Paracetamol 1.0 1.6 3.1 1.3 1.2 1.5 0.2 0.8 1.4 1.8 1.2 1.6 0.7 1.2 1.2 1.2 1.3 1.0 1.2 1.4 1.3 1.4 1.2 1.0 1.4 1.3 1.2 0.9 1.3 0.7 1.3 1.7 1.4 1.3 1.3 1.2 1.5 1.2 1.1 1.5 0.8 1.2 1.4 1.4 1.6 1.4 1.3 1.4
Headache pain in last month 1.4 2.4 6.8 1.6 1.7 1.3 -0.2 0.9 1.8 2.6 1.6 1.6 1.3 0.9 1.5 1.4 1.8 1.1 1.3 1.7 1.4 1.7 1.5 0.7 1.9 1.2 1.3 1.1 1.5 0.7 1.3 2.6 1.4 2.0 1.4 1.8 1.5 1.5 1.5 1.8 0.7 1.4 1.4 1.5 2.0 2.1 1.6 1.8
Medication for cholesterol, blood pressure or diabetes 5.4 9.0 16.3 3.2 3.2 3.2 0.4 2.4 3.1 2.5 2.8 3.7 3.7 3.4 2.8 2.8 3.1 2.5 3.0 3.1 2.4 3.5 2.8 4.0 3.8 2.5 3.0 2.7 3.1 1.5 2.4 3.4 2.9 3.8 3.3 2.9 3.1 2.8 2.1 3.3 1.1 2.9 3.2 2.7 3.8 3.3 2.5 3.5
Glaucoma (self-reported) 1.9 2.2 4.1 -1.4 -1.5 -1.6 -0.3 -1.1 -1.4 -1.1 -1.3 -1.8 -2.0 -1.6 -1.5 -1.5 -1.6 -1.5 -1.3 -1.6 -1.3 -1.6 -1.5 -1.4 -1.3 -1.6 -1.3 -1.4 -1.5 -1.1 -1.5 -1.5 -1.7 -1.7 -1.6 -1.9 -1.5 -1.5 -1.5 -1.6 -0.8 -1.4 -1.5 -1.9 -1.3 -1.6 -1.5 -1.5
Gout (self-reported) 0.1 0.1 1.7 -0.0 0.1 -0.1 0.2 0.1 -0.1 -0.5 0.1 -0.1 -1.3 -0.8 0.3 0.3 0.2 0.3 0.0 0.1 0.3 0.1 0.3 -0.7 -0.1 0.4 0.1 0.3 0.2 0.3 0.4 -0.3 0.2 0.1 0.0 0.1 -0.0 0.2 0.3 -0.0 -0.0 0.2 0.0 0.1 -0.0 -0.1 0.2 -0.0
Hypothyroidism/myxoedema (self-reported) 0.1 0.1 1.3 0.1 -0.1 -0.1 -0.9 -0.5 0.2 0.3 -0.3 -0.2 0.2 -0.2 -0.2 -0.2 -0.0 0.4 -0.2 0.0 -0.3 0.2 -0.2 1.2 0.1 0.0 -0.2 0.1 -0.3 -0.5 -0.3 0.9 0.1 0.4 -0.0 0.3 -0.3 -0.1 -0.1 0.2 -0.9 -0.2 -0.1 0.4 0.1 0.7 -0.0 0.3
Medication: Amlodipine 0.3 0.4 3.5 -0.2 -0.3 -0.4 1.9 0.7 -0.1 -0.1 -0.1 -0.3 -0.4 -0.3 -0.1 -0.1 -0.5 -0.1 0.1 -0.4 0.0 -0.7 -0.1 -1.1 -0.9 -0.4 0.1 -0.0 -0.3 0.9 0.0 -1.0 -0.6 -0.8 -0.3 -0.9 0.2 -0.2 0.0 -0.5 1.5 -0.0 0.1 -0.4 -0.9 -1.3 -0.1 -0.8
Medication: Ventolin 100micrograms inhaler 1.6 2.0 5.5 1.8 1.5 1.6 0.9 1.6 1.8 1.4 1.0 1.7 2.4 1.7 1.0 1.0 1.2 1.5 1.7 1.3 1.3 1.4 1.1 2.2 1.7 1.4 1.6 1.3 1.2 1.1 0.9 2.0 1.4 1.4 1.4 0.8 1.7 1.0 1.1 1.4 0.5 1.3 1.7 1.1 1.6 1.2 0.9 1.5
Birth weight 1.0 2.2 4.7 1.7 1.4 1.8 1.1 1.6 1.6 0.8 0.9 1.5 1.9 1.7 1.1 1.1 1.4 1.8 1.7 1.4 1.4 1.3 1.1 1.4 1.9 2.2 1.6 1.8 1.2 1.3 1.1 1.5 2.0 1.1 1.5 1.6 1.6 1.1 1.4 1.4 0.1 1.4 1.5 1.3 1.8 1.6 1.1 1.6
Chronic bronchitis/emphysema (mother) 0.8 1.0 2.3 0.8 0.9 1.1 1.0 0.8 0.8 0.8 1.1 1.1 1.5 1.0 1.0 1.0 1.1 1.0 0.8 1.0 0.7 0.9 1.0 0.3 0.8 1.0 0.9 0.9 1.0 0.9 1.0 0.8 1.1 1.3 0.9 1.4 1.1 1.0 1.1 1.0 1.0 1.0 0.9 1.0 0.8 0.8 1.2 0.9
High blood pressure (siblings) 0.6 0.8 3.3 -1.2 -0.8 -0.7 0.2 -0.8 -1.1 -0.7 -0.3 -0.9 -1.8 -1.8 -0.3 -0.4 -0.7 -1.1 -1.1 -0.7 -0.3 -0.9 -0.4 -1.8 -1.4 -1.2 -1.0 -0.4 -0.6 0.3 -0.2 -1.1 -0.9 -1.2 -0.9 -0.7 -0.9 -0.3 -0.2 -0.9 0.5 -0.6 -1.3 -0.4 -1.4 -0.6 0.0 -1.2
Forced vital capacity (FVC), Best measure 1.3 4.6 8.2 2.5 2.2 2.3 1.7 2.4 2.3 1.7 1.7 2.1 2.3 1.8 1.8 1.9 2.1 2.9 2.5 2.1 2.1 2.2 1.9 2.2 2.6 2.5 2.4 2.5 1.9 2.0 1.7 1.6 1.9 1.8 2.4 2.3 2.1 1.8 2.0 2.3 0.4 2.2 2.5 2.1 2.4 2.6 1.7 2.5
Body fat percentage 0.1 0.2 5.9 -0.2 -0.3 -0.2 -0.1 -0.1 -0.2 -0.7 -0.5 -0.3 -0.4 -0.1 -0.4 -0.3 -0.3 0.1 -0.0 -0.3 -0.3 -0.2 -0.4 -2.4 -0.3 0.2 -0.1 -0.0 -0.3 0.0 -0.2 -0.6 0.2 -0.6 -0.2 -0.2 -0.1 -0.3 -0.3 -0.1 -0.3 -0.2 -0.0 0.1 -0.2 0.2 -0.2 -0.2
Leg fat percentage (right) 0.1 0.2 7.2 -0.0 -0.0 0.1 0.1 0.1 -0.1 -0.5 -0.0 -0.2 -0.7 -0.2 -0.0 -0.0 -0.0 0.3 0.1 0.0 -0.0 0.0 -0.1 -2.7 -0.0 0.2 0.1 0.4 -0.1 0.1 0.1 -0.7 0.3 -0.3 0.0 0.1 -0.2 0.0 -0.0 0.1 -0.0 0.1 0.1 0.3 -0.0 0.2 0.1 0.0
Arm fat-free mass (right) 0.6 3.1 8.6 2.1 1.8 1.8 0.7 1.7 2.1 2.0 1.1 1.3 0.5 1.2 1.4 1.4 1.8 2.9 2.0 1.8 1.7 2.0 1.5 1.4 2.3 2.2 1.9 2.2 1.4 1.6 1.4 2.0 1.7 1.1 1.9 2.0 1.3 1.5 1.8 1.9 -0.6 1.7 1.9 2.2 2.1 2.3 1.5 2.2
Exposure to tobacco smoke outside home 7.4 9.9 19.1 3.3 3.2 3.3 1.8 3.0 3.4 4.4 3.0 3.6 3.2 3.0 3.0 3.1 3.3 2.9 3.2 3.3 3.1 3.2 3.1 2.3 3.2 3.3 3.2 2.7 3.3 3.0 3.1 3.7 3.0 3.4 3.2 3.0 3.7 3.1 3.2 3.3 2.4 3.2 3.3 2.9 3.2 2.8 3.1 3.1
Comparative body size at age 10 0.5 1.2 2.7 1.1 1.0 1.2 0.9 1.1 0.9 0.2 1.0 0.8 0.6 1.2 1.1 1.1 1.2 1.5 1.1 1.2 1.2 1.2 1.1 0.2 1.4 1.1 1.2 1.6 1.0 1.2 1.2 0.3 1.1 0.6 1.1 1.4 0.9 1.2 1.3 1.2 0.1 1.2 1.2 1.6 1.3 1.4 1.0 1.1
Number of full brothers 0.6 0.8 2.6 1.1 1.0 1.0 0.3 0.7 1.1 0.9 0.5 0.9 0.4 0.4 0.6 0.6 0.8 1.0 1.0 0.9 0.8 1.0 0.6 0.9 1.4 1.3 0.9 0.9 0.7 0.5 0.5 1.6 1.0 0.5 1.0 0.9 0.8 0.5 0.6 1.0 -0.3 0.8 0.8 0.7 1.3 1.4 0.6 1.2
Worry too long after embarrassment 1.3 2.2 5.5 -1.1 -1.5 -1.1 -1.0 -1.1 -1.2 -2.3 -1.9 -1.6 -0.9 -0.9 -1.9 -1.8 -1.6 -1.1 -1.1 -1.6 -1.8 -1.5 -1.8 0.8 -0.8 -1.0 -1.2 -0.9 -1.8 -1.9 -1.9 -1.4 -1.5 -1.8 -1.4 -1.7 -1.7 -1.9 -1.8 -1.4 -2.0 -1.5 -1.2 -1.8 -0.8 -0.1 -1.9 -1.2
Seen a psychiatrist for nerves, anxiety, tension or depression 0.9 1.1 2.1 -0.9 -1.1 -0.8 0.1 -0.6 -0.6 -0.5 -1.4 -1.2 -1.2 -1.3 -1.4 -1.4 -1.2 -0.8 -0.9 -1.1 -0.7 -1.5 -1.3 -0.9 -1.1 -1.3 -1.0 -0.9 -1.4 -0.7 -1.3 -0.3 -1.3 -1.1 -1.2 -1.3 -1.0 -1.3 -0.8 -1.1 -0.5 -1.2 -0.9 -1.3 -1.1 -0.5 -1.1 -1.3
Wheeze or whistling in the chest in last year 4.0 7.1 11.3 2.7 2.7 2.9 2.6 2.9 2.8 2.6 2.5 2.9 2.5 2.9 2.5 2.6 2.6 3.4 2.8 2.7 2.9 2.4 2.6 2.1 2.5 2.9 2.8 2.9 2.6 2.9 2.5 2.4 2.4 2.4 2.7 2.5 2.9 2.6 2.8 2.7 2.4 2.7 2.6 2.5 2.5 2.6 2.7 2.3
Number of children fathered 3.1 3.5 6.7 -1.8 -1.9 -2.1 -2.6 -2.4 -1.8 -1.8 -1.9 -1.3 -1.2 -2.1 -1.9 -2.0 -1.9 -1.9 -2.1 -1.9 -1.8 -1.5 -1.9 -0.3 -1.5 -2.1 -2.1 -2.2 -1.8 -2.5 -2.1 -0.5 -1.9 -1.2 -1.8 -1.8 -1.9 -2.0 -2.1 -1.8 -2.2 -2.0 -2.2 -1.8 -1.5 -1.7 -2.0 -1.4
Reason for reducing amount of alcohol drunk: Health precaution 1.3 1.5 4.0 1.0 1.2 1.4 2.0 1.4 1.1 0.9 1.1 1.2 0.6 1.2 1.3 1.3 1.1 1.4 1.1 1.1 1.3 0.9 1.3 0.8 0.6 1.7 1.1 1.4 1.2 1.8 1.4 0.8 1.2 1.1 1.1 1.5 1.2 1.3 1.7 1.0 1.3 1.2 1.0 1.4 0.6 0.8 1.4 0.8
Age at first live birth 0.2 0.4 4.5 -0.9 -0.4 -0.6 0.4 -0.2 -1.2 -1.3 0.3 -0.4 0.2 -0.3 0.3 0.3 -0.1 -0.5 -0.6 -0.3 0.0 -0.3 0.1 -0.1 -0.8 -0.9 -0.4 0.2 0.1 0.5 0.3 -2.1 -0.2 0.0 -0.4 0.2 -0.4 0.2 0.6 -0.7 -0.3 -0.1 -0.8 0.1 -1.0 -0.4 0.2 -0.7
Pulse wave peak to peak time 0.2 0.3 1.4 0.6 0.6 0.5 -0.2 0.4 0.6 1.1 0.4 1.0 1.2 0.6 0.3 0.3 0.4 0.2 0.6 0.4 0.8 0.5 0.4 -0.3 0.5 0.8 0.5 0.3 0.5 0.2 0.2 1.1 0.1 0.5 0.5 0.2 0.9 0.3 0.3 0.4 -0.0 0.4 0.5 0.0 0.4 -0.2 0.1 0.6
Health satisfaction 1.9 2.5 4.3 -1.5 -1.6 -1.6 -0.6 -1.2 -1.4 -0.9 -1.9 -2.0 -1.4 -1.2 -2.0 -2.0 -1.8 -0.9 -1.5 -1.7 -1.7 -1.9 -1.9 -2.0 -1.6 -1.3 -1.6 -0.8 -2.1 -1.3 -1.8 -1.5 -1.3 -1.8 -1.7 -1.3 -1.7 -1.9 -1.1 -1.7 -1.2 -1.7 -1.5 -1.5 -1.6 -1.4 -1.7 -1.9
Shortness of breath walking on level ground 0.3 0.4 2.0 -0.1 -0.5 -0.4 0.2 -0.1 -0.0 -0.8 -0.8 -1.0 -1.2 -1.4 -0.8 -0.8 -0.6 0.3 -0.1 -0.5 -0.2 -0.6 -0.7 -1.0 -0.1 -0.4 -0.2 0.3 -0.9 -0.6 -0.8 -0.7 -0.4 -1.0 -0.4 -0.6 -0.8 -0.8 -0.8 -0.3 -0.2 -0.5 -0.3 -0.6 -0.1 0.1 -0.6 -0.2
Qualifications: College or University degree 0.3 1.0 6.3 -1.1 -0.8 -1.0 0.9 -0.2 -1.1 -0.7 -0.6 -1.2 -0.9 -1.0 -0.6 -0.6 -1.0 -0.9 -0.8 -1.0 -0.6 -1.3 -0.7 -2.5 -1.6 -0.8 -0.7 -0.7 -0.8 0.4 -0.5 -1.8 -1.2 -1.0 -1.1 -0.8 -0.8 -0.6 -0.1 -1.1 0.2 -0.7 -0.8 -0.9 -1.6 -0.9 -0.6 -1.4
Eye problems/disorders: None of the above 0.5 0.5 1.9 -0.8 -0.8 -0.7 0.2 -0.5 -0.8 -1.0 -0.7 -0.7 -0.5 -0.1 -0.8 -0.8 -0.7 -0.6 -0.6 -0.7 -1.0 -0.8 -0.8 -1.0 -0.6 -0.4 -0.6 -0.7 -0.8 -0.7 -0.7 -1.4 -0.7 -1.0 -0.7 -0.7 -0.8 -0.7 -0.9 -0.6 0.4 -0.7 -0.6 -0.4 -0.5 -0.4 -0.6 -0.9
Mouth/teeth dental problems: Loose teeth 0.4 0.5 1.4 0.9 0.6 0.7 0.2 0.8 0.8 0.2 0.2 1.2 1.1 0.9 0.5 0.5 0.6 0.7 0.9 0.6 0.6 0.7 0.5 1.1 1.0 0.6 0.8 0.5 0.7 0.2 0.4 0.8 0.6 0.4 0.8 0.6 1.0 0.4 0.2 0.7 0.3 0.7 1.0 0.2 1.0 0.8 0.2 0.8
Emphysema/chronic bronchitis 2.7 3.0 7.0 -1.4 -1.8 -1.6 -1.5 -1.6 -1.3 -1.5 -2.1 -1.5 -0.6 -0.5 -2.3 -2.2 -2.0 -1.6 -1.5 -1.9 -1.9 -1.8 -2.2 0.3 -1.1 -0.8 -1.6 -1.7 -2.1 -2.4 -2.3 -0.7 -1.5 -1.6 -1.6 -2.2 -1.7 -2.3 -2.3 -1.7 -1.8 -1.9 -1.5 -2.6 -1.1 -1.1 -2.3 -1.4
Medication for pain relief, constipation, heartburn 0.2 0.3 1.9 0.1 0.5 0.2 0.5 0.5 -0.1 -0.0 0.7 0.5 1.4 0.7 0.7 0.7 0.5 0.1 0.2 0.4 0.3 0.5 0.6 0.5 0.2 0.1 0.3 0.4 0.7 0.6 0.6 -0.3 0.5 1.0 0.4 0.6 0.4 0.7 0.5 0.2 0.6 0.5 0.2 0.6 0.2 -0.1 0.5 0.2
Neck or shoulder pain in last month 1.0 1.5 4.5 1.4 1.3 1.4 -0.0 0.9 1.5 2.1 0.9 1.4 1.0 1.6 1.0 1.1 1.2 0.9 1.2 1.3 0.9 1.3 1.1 0.3 1.3 1.2 1.2 1.0 1.2 0.7 1.1 2.1 1.7 1.4 1.2 1.0 1.4 1.0 1.1 1.2 0.5 1.2 1.4 0.8 1.3 0.7 1.0 1.3
Medication: Blood pressure 3.6 6.3 14.8 -2.6 -2.6 -2.7 -0.4 -2.1 -2.4 -2.1 -2.4 -3.2 -3.8 -3.1 -2.4 -2.4 -2.6 -1.9 -2.5 -2.5 -1.9 -2.8 -2.4 -3.4 -2.9 -2.3 -2.4 -2.1 -2.7 -1.4 -2.1 -2.6 -2.5 -3.2 -2.7 -2.6 -2.8 -2.4 -1.9 -2.7 -1.3 -2.5 -2.5 -2.3 -2.9 -2.6 -2.2 -2.7
Angina (self-reported) 0.9 1.2 3.2 -1.1 -1.2 -1.0 0.1 -0.9 -1.0 -1.1 -1.0 -1.1 -1.7 -1.5 -1.0 -1.0 -1.1 -0.6 -1.0 -1.0 -0.8 -1.3 -1.0 -1.8 -1.6 -0.6 -1.1 -0.9 -1.1 -0.6 -0.7 -1.0 -0.9 -1.6 -1.1 -1.0 -1.1 -1.0 -0.9 -1.1 0.1 -1.0 -1.2 -0.7 -1.5 -1.2 -0.7 -1.2
Migraine (self-reported) 0.1 0.2 1.7 -0.2 -0.2 -0.8 -1.3 -0.8 -0.2 -0.5 -0.3 -0.5 -0.2 -0.4 -0.3 -0.3 -0.1 -0.0 -0.4 -0.0 -0.2 0.0 -0.3 -0.3 0.1 -0.8 -0.4 -0.0 -0.4 -0.8 -0.4 -0.1 -0.4 -0.3 -0.2 0.2 -0.5 -0.2 -0.4 0.1 -0.8 -0.3 -0.3 0.0 0.1 0.3 -0.2 0.2
Medication: Ibuprofen 0.7 0.8 2.9 1.1 0.8 0.9 0.7 1.0 1.1 0.7 0.3 1.0 1.2 1.2 0.5 0.6 0.8 1.2 1.1 0.8 0.8 0.8 0.6 0.8 1.1 1.7 1.0 1.0 0.7 0.7 0.6 1.1 0.9 0.7 1.0 0.7 1.1 0.6 0.8 1.0 0.3 0.8 1.1 0.7 1.1 1.1 0.6 0.9
Medication: Allopurinol 0.3 0.4 1.8 -0.7 -0.5 -0.6 0.2 -0.2 -0.7 -1.4 -0.6 -0.5 -1.3 -1.1 -0.3 -0.3 -0.6 -0.3 -0.5 -0.6 -0.2 -0.6 -0.4 -1.0 -0.8 -0.1 -0.4 -0.2 -0.4 -0.1 -0.2 -1.0 -0.5 -0.5 -0.6 -0.5 -0.5 -0.4 -0.3 -0.8 -0.2 -0.4 -0.5 -0.6 -0.8 -0.9 -0.5 -0.8
Medication: Omeprazole 0.6 0.8 1.6 -0.8 -0.9 -1.1 -0.7 -1.0 -0.8 -0.6 -0.9 -0.9 -0.5 -0.6 -0.9 -0.9 -0.9 -1.3 -0.9 -0.8 -1.0 -0.9 -0.8 -0.9 -0.9 -0.9 -1.0 -0.7 -0.9 -0.8 -0.8 -0.3 -0.7 -1.1 -1.0 -1.0 -0.7 -0.8 -0.7 -0.9 -0.6 -0.9 -0.8 -0.9 -0.9 -1.2 -0.9 -0.9
Medication: Seretide 50 evohaler 0.5 0.6 2.6 -0.4 -0.5 -0.8 -1.6 -1.0 -0.2 -0.5 -1.0 -0.5 0.2 -0.6 -1.0 -0.9 -0.7 -0.4 -0.7 -0.6 -0.7 -0.5 -0.9 0.8 -0.3 -0.9 -0.8 -0.8 -0.8 -1.1 -1.1 1.0 -0.8 -0.3 -0.6 -0.5 -0.7 -0.9 -0.7 -0.5 -1.4 -0.8 -0.6 -0.7 -0.4 -0.4 -0.9 -0.2
Mean time to correctly identify matches 1.4 2.7 5.9 1.9 1.7 2.0 0.4 1.0 2.0 1.9 1.5 1.4 1.1 0.8 1.5 1.5 1.6 1.7 1.5 1.9 1.6 1.9 1.6 2.4 1.8 0.8 1.6 1.5 1.5 0.9 1.4 2.2 1.4 2.1 1.8 1.6 1.4 1.6 1.2 2.0 1.1 1.6 1.6 1.6 1.9 2.0 1.7 2.1
Heart disease (mother) 0.9 1.1 2.8 0.9 1.0 1.4 0.9 0.9 1.0 1.7 1.0 1.0 0.9 1.0 1.1 1.1 1.0 0.8 0.8 1.1 1.1 0.9 1.1 0.6 0.6 0.9 0.9 0.7 1.1 1.1 1.2 1.2 1.4 1.3 0.9 1.0 1.1 1.1 1.4 1.0 0.9 1.0 1.0 1.0 0.7 0.7 1.1 0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.2 0.5 0.2 0.3 0.3 0.5 0.4 0.2 0.3 0.4 0.5 0.5 -0.0 0.5 0.5 0.4 0.2 0.2 0.3 0.7 0.3 0.5 -0.5 0.3 0.0 0.3 0.3 0.5 0.7 0.6 0.2 0.5 0.1 0.3 0.2 0.5 0.5 0.7 0.3 0.3 0.4 0.3 0.3 0.2 0.2 0.4 0.1
Whole body fat mass 0.1 0.3 2.9 0.6 0.4 0.5 0.4 0.6 0.5 0.1 -0.0 0.1 -0.2 0.3 0.2 0.2 0.3 1.1 0.7 0.4 0.4 0.4 0.2 -1.7 0.4 1.0 0.6 0.8 0.2 0.7 0.4 -0.0 0.9 -0.2 0.5 0.5 0.3 0.3 0.4 0.5 -0.3 0.5 0.6 0.8 0.4 0.9 0.4 0.5
Leg fat mass (right) 0.1 0.3 3.6 0.4 0.3 0.4 0.1 0.4 0.3 -0.0 0.1 0.0 -0.5 0.2 0.2 0.3 0.3 1.0 0.5 0.3 0.3 0.4 0.2 -1.9 0.4 0.5 0.5 0.7 0.2 0.4 0.4 -0.2 0.6 -0.2 0.4 0.5 0.1 0.3 0.3 0.4 -0.3 0.4 0.5 0.8 0.4 0.9 0.4 0.5
Arm predicted mass (right) 0.6 2.9 8.2 2.0 1.7 1.8 1.0 1.8 1.9 2.0 1.1 1.2 0.4 1.2 1.3 1.4 1.7 2.9 1.9 1.7 1.7 1.8 1.4 1.0 2.1 2.2 1.8 2.2 1.3 1.6 1.4 1.7 1.8 0.9 1.9 1.9 1.2 1.4 1.8 1.8 -0.3 1.6 1.8 2.1 2.0 2.1 1.5 2.0
Pulse rate, automated reading 0.1 0.2 2.8 -0.4 -0.3 -0.5 0.3 0.1 -0.7 -1.0 -0.1 -0.3 -0.2 -0.2 -0.1 -0.1 -0.2 -0.1 -0.1 -0.3 -0.3 -0.2 -0.2 -1.3 -0.3 -0.0 -0.1 -0.0 -0.1 -0.0 0.0 -1.7 0.4 -0.5 -0.2 -0.4 -0.1 -0.1 -0.3 -0.4 -0.0 -0.1 -0.0 -0.2 -0.2 -0.2 -0.2 -0.4
Alcohol intake frequency. 0.2 0.5 3.0 -0.7 -0.5 -0.7 -1.0 -1.0 -0.5 0.8 -0.4 -0.7 -0.9 -1.0 -0.5 -0.6 -0.3 -0.1 -0.9 -0.4 -0.8 -0.4 -0.5 -1.7 -0.6 -0.0 -0.9 -0.6 -0.6 -0.3 -0.4 0.5 -0.1 -0.6 -0.6 0.2 -1.0 -0.5 0.1 -0.4 -1.4 -0.7 -1.0 -0.1 -0.6 0.0 -0.1 -0.2
Comparative height size at age 10 0.0 0.2 2.0 0.1 0.1 0.0 -1.3 -0.4 0.2 0.4 -0.3 -0.3 -0.6 -0.9 -0.2 -0.2 0.0 0.0 -0.1 -0.0 -0.1 0.2 -0.1 0.9 0.4 0.3 -0.2 -0.4 -0.2 -0.5 -0.2 1.1 0.0 0.0 -0.1 -0.0 -0.3 -0.1 -0.0 0.1 -1.4 -0.2 -0.0 -0.1 0.3 0.8 -0.2 0.2
Number of full sisters 1.1 1.4 2.7 1.3 1.4 1.0 0.9 1.2 1.3 1.6 1.0 0.8 0.7 0.6 1.1 1.1 1.3 1.6 1.2 1.3 1.3 1.2 1.2 0.2 1.4 1.4 1.2 1.5 0.9 1.2 1.0 1.2 1.1 0.9 1.2 1.6 0.7 1.1 1.3 1.3 0.2 1.1 1.0 1.5 1.3 1.4 1.2 1.3
Suffer from ‘nerves’ 0.7 1.1 2.4 -1.3 -1.1 -1.0 0.4 -0.6 -1.3 -1.5 -1.1 -0.8 0.2 -0.4 -1.1 -1.1 -1.1 -1.2 -1.1 -1.1 -1.2 -1.5 -1.1 -1.3 -1.1 -1.2 -1.1 -1.0 -1.1 -0.7 -1.1 -1.5 -1.2 -0.7 -1.2 -1.0 -0.7 -1.1 -0.8 -1.2 -0.2 -1.1 -1.1 -1.0 -1.0 -0.4 -0.9 -1.6
Overall health rating 0.3 0.6 3.3 0.8 0.8 0.7 -0.2 0.4 1.0 1.6 0.4 1.2 1.2 1.0 0.4 0.4 0.6 0.2 0.7 0.7 0.4 0.6 0.5 -0.2 1.0 1.1 0.5 0.2 0.6 -0.0 0.3 1.8 0.8 0.8 0.5 0.2 1.2 0.4 0.3 0.7 0.7 0.5 0.7 0.3 1.2 0.1 0.4 0.6
Chest pain or discomfort 0.2 0.3 1.2 -0.4 -0.6 -0.3 0.6 0.1 -0.3 -0.4 -0.9 -0.4 0.3 -0.2 -0.8 -0.7 -0.6 -0.2 -0.3 -0.6 -0.4 -1.0 -0.7 -1.1 -0.4 -0.3 -0.3 -0.6 -0.7 -0.3 -0.7 -0.7 -0.6 -0.7 -0.6 -0.8 -0.0 -0.7 -0.5 -0.5 0.6 -0.5 -0.3 -0.5 -0.4 -0.6 -0.6 -0.9
Had major operations 0.7 0.8 3.6 -0.7 -0.7 -1.1 -1.9 -1.3 -0.7 -0.5 -0.7 -0.9 -0.6 -0.8 -0.8 -0.8 -0.7 -1.1 -0.9 -0.7 -1.3 -0.4 -0.8 -0.3 -0.5 -1.1 -0.9 -1.1 -0.8 -1.4 -0.9 0.1 -0.6 -0.8 -0.8 -1.0 -1.1 -0.8 -1.2 -0.7 -1.1 -0.9 -0.8 -0.8 -0.4 -0.9 -1.0 -0.4
Age at last live birth 0.1 0.2 3.2 -0.6 -0.3 -0.1 0.3 0.0 -0.9 -1.1 0.1 -0.1 -0.2 -0.5 0.2 0.2 -0.0 -0.3 -0.3 -0.2 0.2 -0.2 0.1 0.1 -0.3 -0.5 -0.2 0.2 0.1 0.4 0.2 -1.8 0.1 -0.1 -0.3 0.1 -0.3 0.1 0.4 -0.5 -0.4 -0.0 -0.6 0.0 -0.5 0.3 0.1 -0.5
Family relationship satisfaction 1.9 2.4 10.4 1.5 1.6 1.9 3.2 2.4 1.5 1.9 1.4 1.1 0.9 1.3 1.3 1.4 1.3 1.8 1.7 1.4 1.6 0.8 1.4 -0.9 1.1 1.3 1.7 1.8 1.3 2.4 1.6 0.4 1.5 0.8 1.3 1.3 1.6 1.3 1.9 1.2 2.1 1.5 1.8 1.2 1.1 0.8 1.4 0.8
Leg pain on walking 0.1 0.1 0.3 0.4 0.1 0.5 0.3 0.4 0.4 0.2 -0.4 0.0 0.2 -0.1 -0.2 -0.2 -0.0 0.5 0.3 0.1 -0.2 -0.0 -0.1 -0.4 0.3 0.5 0.2 0.2 -0.2 -0.1 -0.1 0.4 0.3 -0.0 0.1 0.0 0.4 -0.2 0.1 0.1 0.2 0.1 0.3 0.2 0.3 -0.1 -0.1 -0.1
Qualifications: NVQ or HND or HNC or equivalent 4.5 5.5 12.0 2.7 2.5 2.3 0.5 2.0 2.7 2.7 1.8 2.3 2.3 1.6 1.9 2.0 2.4 2.6 2.5 2.4 2.4 2.5 2.1 3.5 2.9 3.1 2.3 2.4 2.1 1.4 1.7 2.9 1.9 2.4 2.5 2.4 2.2 2.0 2.0 2.6 0.3 2.2 2.6 2.3 2.8 2.5 1.8 2.8
Commuting to job workplace: Car/motor vehicle 2.5 2.9 4.8 1.7 1.8 1.5 1.3 1.6 1.7 1.5 1.8 1.5 1.2 1.8 1.8 1.8 1.9 1.8 1.7 1.8 1.5 1.9 1.8 1.2 1.9 2.2 1.7 2.0 1.7 1.8 1.8 1.2 1.8 1.8 1.8 1.8 1.4 1.8 1.9 1.8 0.6 1.8 1.6 1.5 1.9 1.9 1.8 1.8
Illness, injury, bereavement, stress in last 2 years 0.9 1.1 4.8 -1.2 -1.1 -0.8 1.3 -0.2 -1.2 -1.6 -0.7 -0.8 -0.3 -0.0 -0.6 -0.6 -1.1 -1.0 -0.7 -1.1 -0.7 -1.3 -0.7 -1.7 -1.8 -0.5 -0.7 -0.7 -0.6 0.3 -0.4 -2.2 -0.8 -1.2 -0.8 -1.2 -0.8 -0.7 -0.6 -1.3 0.8 -0.7 -1.0 -1.1 -1.8 -2.2 -0.6 -1.4
Medication: Aspirin 1.0 1.3 4.2 -0.9 -1.2 -1.0 -0.4 -0.9 -0.7 -0.2 -1.1 -1.4 -2.0 -1.6 -1.2 -1.2 -1.3 -0.7 -1.0 -1.1 -0.8 -1.3 -1.1 -1.3 -1.3 -0.8 -1.0 -0.9 -1.3 -1.0 -1.1 -0.6 -1.3 -1.4 -1.2 -1.1 -1.1 -1.2 -1.0 -1.2 -0.5 -1.1 -1.0 -0.9 -1.4 -1.4 -1.0 -1.1
Supplements: Vitamin C 0.2 0.2 0.8 -0.3 -0.5 -0.0 0.2 -0.4 -0.2 0.2 -0.6 -0.8 -0.9 -0.2 -0.7 -0.7 -0.6 0.2 -0.4 -0.4 -0.5 -0.6 -0.6 -0.1 -0.6 -0.0 -0.5 -0.2 -0.8 -0.1 -0.5 0.1 -0.0 -0.8 -0.4 -0.2 -0.5 -0.6 -0.0 -0.4 -0.5 -0.6 -0.4 -0.0 -0.8 -0.5 -0.4 -0.5
Knee pain experienced in last month 0.0 0.1 1.2 -0.2 -0.2 0.0 -0.3 -0.2 -0.2 0.0 -0.3 0.2 -0.5 0.3 -0.2 -0.2 -0.2 -0.0 -0.2 -0.1 -0.2 -0.1 -0.2 -1.1 -0.3 -0.3 -0.2 -0.2 -0.1 -0.0 -0.1 0.1 -0.0 -0.2 -0.1 -0.2 0.1 -0.1 0.1 -0.1 -0.2 -0.2 -0.1 0.0 -0.3 0.2 -0.1 -0.4
Hypertension (Self-reported) 0.7 1.9 11.2 -1.3 -1.3 -1.4 1.0 -0.5 -1.2 -0.8 -1.0 -1.6 -1.8 -1.6 -1.0 -1.0 -1.4 -1.1 -1.0 -1.2 -0.8 -1.6 -1.0 -3.3 -1.9 -1.0 -1.0 -1.0 -1.2 -0.0 -0.7 -2.1 -1.3 -1.8 -1.4 -1.6 -1.0 -1.0 -0.9 -1.5 0.8 -1.1 -1.1 -1.1 -1.9 -2.2 -0.9 -1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 0.7 -0.6 -0.7 -0.7 -0.3 -0.6 -0.5 -0.6 -0.8 -0.7 -0.5 -0.6 -0.6 -0.6 -0.7 -0.6 -0.5 -0.6 -0.8 -0.6 -0.6 -0.5 -0.7 -0.8 -0.5 -0.4 -0.7 -0.4 -0.6 -0.7 -0.8 -0.7 -0.6 -0.7 -0.7 -0.6 -0.6 -0.6 -0.4 -0.5 -0.4 -0.5 -0.8 -0.5 -0.6 -0.6
Illnesses of father: Heart disease 0.3 0.5 1.3 -0.8 -0.4 -1.0 -1.0 -1.0 -0.6 0.6 -0.3 -0.8 -1.0 -1.0 -0.3 -0.4 -0.4 -0.8 -0.9 -0.4 -0.5 -0.5 -0.3 -1.0 -0.5 -1.1 -0.9 -0.9 -0.5 -0.6 -0.4 0.2 -1.1 -0.2 -0.8 -0.4 -1.0 -0.4 -0.1 -0.5 -0.9 -0.6 -1.0 -0.7 -0.5 0.4 -0.2 -0.7
Illnesses of siblings: Diabetes 0.4 0.5 1.8 0.5 0.8 0.7 -0.5 -0.1 0.5 1.0 0.8 0.5 0.1 -0.3 0.8 0.7 0.8 0.4 0.3 0.8 0.9 1.0 0.8 0.3 0.6 0.8 0.3 0.8 0.7 0.2 0.8 1.4 0.8 1.0 0.6 1.1 0.5 0.8 0.8 0.7 -0.3 0.5 0.2 1.0 0.6 0.7 0.9 0.8
Smoking status: Previous 2.1 3.1 4.7 1.8 1.9 1.7 0.9 1.5 1.8 1.5 1.9 1.8 1.3 0.8 2.0 1.9 2.0 1.5 1.7 2.0 2.2 2.0 2.0 1.7 2.1 1.7 1.7 1.9 1.9 1.6 1.8 1.7 1.4 1.6 1.8 1.8 1.7 1.9 1.8 2.0 1.0 1.9 1.8 1.6 2.1 2.1 1.9 1.9
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 2.6 1.0 0.7 1.0 1.3 1.2 0.9 0.6 0.3 0.6 0.7 0.8 0.5 0.5 0.6 1.3 1.0 0.7 0.9 0.5 0.6 0.5 0.7 1.6 0.9 1.1 0.6 1.2 0.6 0.4 1.1 0.2 0.8 0.9 0.8 0.5 1.0 0.7 0.2 0.8 1.0 0.7 0.6 0.8 0.5 0.8
Whole body fat-free mass 0.7 4.1 9.6 2.4 2.0 2.2 1.4 2.1 2.2 2.3 1.4 1.6 0.9 1.7 1.8 1.8 1.9 3.1 2.3 2.0 2.0 2.1 1.9 1.1 2.2 2.7 2.2 2.4 1.7 2.1 1.9 1.9 2.2 1.2 2.2 2.2 1.7 1.8 2.2 2.1 0.0 2.0 2.2 2.4 2.1 2.2 1.8 2.3
Leg fat-free mass (right) 0.8 4.0 8.7 2.2 2.0 2.0 1.6 2.2 2.2 2.3 1.4 1.6 1.2 2.0 1.8 1.8 1.9 3.0 2.3 2.0 2.0 2.0 1.9 0.8 2.0 2.6 2.1 2.3 1.8 2.3 1.9 1.9 2.1 1.2 2.1 2.3 1.9 1.9 2.3 2.1 0.5 2.0 2.2 2.5 1.9 2.1 1.9 2.1
Arm fat percentage (left) 0.2 0.6 3.0 0.8 0.6 0.6 0.7 0.8 0.7 0.2 0.3 0.7 0.6 0.9 0.6 0.6 0.6 1.1 1.0 0.7 0.6 0.7 0.6 -1.7 0.5 1.3 0.9 0.9 0.7 1.0 0.8 0.3 1.0 0.2 0.8 0.8 0.9 0.7 0.7 0.8 0.6 0.8 0.9 1.0 0.5 0.8 0.8 0.7
Average weekly red wine intake 1.4 2.1 4.6 -1.7 -1.6 -1.6 0.3 -0.8 -1.7 -2.0 -1.4 -1.3 -0.5 -1.3 -1.2 -1.2 -1.5 -1.7 -1.5 -1.6 -1.1 -1.9 -1.2 -1.6 -2.1 -1.2 -1.5 -1.5 -1.2 -0.5 -1.2 -1.9 -1.8 -1.5 -1.6 -1.3 -1.1 -1.2 -0.8 -1.7 0.1 -1.3 -1.5 -1.2 -2.1 -1.9 -1.2 -2.2
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.6 -0.3 -0.3 -0.3 -0.0 -0.1 -0.3 -0.2 -0.3 0.0 -0.6 -0.3 -0.3 -0.3 -0.4 -0.1 -0.2 -0.3 -0.1 -0.3 -0.3 0.8 -0.5 0.0 -0.3 -0.0 -0.2 -0.1 -0.2 -0.3 -0.1 -0.4 -0.2 -0.5 -0.2 -0.4 -0.3 -0.4 -0.2 -0.3 -0.1 -0.6 -0.4 0.1 -0.3 -0.3
Mood swings 0.3 0.6 1.4 -0.8 -0.8 -1.1 -0.7 -0.8 -0.7 -0.9 -0.8 -0.6 -0.3 -0.8 -0.7 -0.8 -0.8 -1.2 -0.8 -0.8 -0.7 -0.9 -0.7 -0.2 -0.7 -0.9 -0.9 -1.0 -0.7 -0.9 -0.9 -0.2 -0.9 -0.9 -0.9 -1.1 -0.6 -0.8 -0.9 -0.8 -0.1 -0.8 -0.8 -0.8 -0.7 -0.5 -0.7 -0.9
Loneliness, isolation 0.2 0.2 1.0 0.0 -0.4 0.2 0.6 0.3 0.1 -0.1 -1.0 -0.4 0.1 -0.1 -0.9 -0.8 -0.6 0.1 0.0 -0.5 -0.2 -0.7 -0.7 -0.6 -0.1 0.3 -0.1 -0.0 -0.7 -0.3 -0.7 0.1 -0.2 -0.6 -0.4 -0.6 -0.1 -0.9 -0.5 -0.4 -0.4 -0.5 0.1 -0.8 -0.1 0.0 -0.8 -0.4
Long-standing illness, disability or infirmity 0.1 0.1 0.8 0.2 0.2 0.0 0.5 0.2 0.3 0.8 0.1 -0.1 -0.6 -0.9 0.2 0.2 0.1 0.1 0.2 0.2 0.3 -0.0 0.2 -0.7 0.1 -0.0 0.2 0.1 0.0 0.6 0.2 0.3 0.3 -0.1 -0.0 -0.0 0.1 0.2 0.4 0.2 0.6 0.2 0.1 -0.0 0.1 0.8 0.5 -0.0
Ever had bowel cancer screening 0.7 0.8 3.2 -0.2 -0.5 -0.8 -1.8 -1.2 -0.2 -0.7 -0.8 -0.9 -1.3 -1.1 -1.0 -0.9 -0.7 -0.4 -0.6 -0.6 -0.6 -0.3 -0.9 1.3 0.2 -1.3 -0.6 -0.5 -1.0 -1.3 -1.2 0.3 -0.9 -0.9 -0.5 -0.9 -1.2 -1.0 -1.2 -0.3 -1.6 -0.8 -0.4 -1.3 0.2 0.9 -0.9 0.1
Diabetes diagnosed by doctor 1.0 1.6 3.5 -1.0 -1.3 -1.1 -0.8 -1.2 -0.9 -0.5 -1.5 -1.1 -1.2 -1.8 -1.4 -1.4 -1.5 -1.1 -1.2 -1.4 -0.9 -1.4 -1.4 -1.2 -1.3 -1.2 -1.2 -1.3 -1.4 -1.4 -1.5 -0.4 -1.2 -1.3 -1.3 -1.7 -1.0 -1.5 -1.5 -1.3 -0.6 -1.3 -1.1 -1.5 -1.3 -1.9 -1.5 -1.2
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 1.8 0.5 0.4 0.6 0.9 0.7 0.5 0.7 0.4 0.4 0.7 0.8 0.5 0.5 0.4 0.4 0.6 0.4 0.6 0.4 0.5 0.6 0.1 1.4 0.6 0.6 0.5 0.6 0.6 -0.0 0.5 0.5 0.5 0.6 0.4 0.5 0.5 0.4 0.6 0.5 0.4 0.5 0.1 0.2 0.5 0.5
Friendships satisfaction 0.7 0.9 4.5 0.5 0.8 1.0 2.1 1.6 0.6 1.5 0.8 0.5 1.0 1.1 0.7 0.7 0.7 1.3 0.7 0.6 0.7 0.1 0.7 -1.7 0.3 0.7 0.8 0.9 0.6 1.6 0.9 -0.0 0.7 0.6 0.5 1.0 1.0 0.7 1.7 0.4 1.2 0.7 0.8 1.3 0.2 0.2 0.8 -0.1
Qualifications: nursing, teaching 0.4 0.6 2.9 -0.8 -0.7 -0.7 0.7 -0.0 -0.7 -0.6 -0.8 -0.8 -0.9 -0.3 -0.5 -0.5 -0.8 -0.5 -0.5 -0.8 -0.5 -1.0 -0.5 -1.7 -1.3 -1.0 -0.4 -0.5 -0.7 0.2 -0.4 -1.5 -0.7 -0.7 -0.7 -0.9 -0.5 -0.5 -0.3 -0.8 0.7 -0.5 -0.4 -0.7 -1.3 -0.9 -0.5 -1.2
Commuting to job workplace: Walk 1.3 1.4 2.2 -0.9 -1.2 -0.9 -0.7 -0.8 -0.8 -0.7 -1.4 -1.2 -1.3 -1.1 -1.5 -1.4 -1.4 -0.8 -0.9 -1.3 -1.1 -1.3 -1.4 -0.7 -1.1 -0.9 -1.0 -1.1 -1.4 -1.4 -1.4 -0.6 -1.1 -1.4 -1.1 -1.4 -1.0 -1.4 -1.5 -1.2 -0.8 -1.2 -1.0 -1.3 -1.1 -1.4 -1.5 -1.0
Eye problems/disorders: Cataract 0.8 0.9 2.8 -1.2 -0.9 -1.1 -0.2 -0.9 -1.2 -0.4 -0.4 -1.2 -1.5 -1.0 -0.5 -0.6 -0.8 -1.0 -1.2 -0.8 -0.5 -0.9 -0.6 -1.7 -1.7 -1.6 -1.1 -0.7 -0.7 -0.2 -0.4 -1.1 -1.0 -0.6 -1.0 -0.6 -1.0 -0.6 -0.3 -1.1 0.1 -0.8 -1.3 -0.6 -1.7 -1.2 -0.3 -1.1
Mouth/teeth dental problems: Mouth ulcers 0.0 0.0 0.4 -0.0 0.0 -0.2 -0.2 0.1 -0.1 0.1 0.1 0.3 -0.3 0.2 0.2 0.2 0.1 -0.2 0.0 0.1 0.1 0.1 0.2 -0.4 0.1 0.2 0.0 -0.1 0.2 -0.1 0.2 -0.2 0.1 -0.2 0.0 -0.1 0.3 0.2 -0.1 0.1 0.7 0.1 0.0 0.1 0.2 0.1 0.2 -0.2
Medication for cholesterol 0.3 0.5 4.6 0.2 0.2 0.1 -1.9 -0.6 0.2 0.4 -0.1 0.3 1.0 1.2 -0.0 -0.0 0.4 0.2 -0.1 0.2 -0.5 0.7 0.0 1.5 0.8 0.4 -0.1 -0.2 0.2 -0.6 -0.0 1.3 0.7 0.4 0.1 0.8 0.0 0.1 0.3 0.4 -2.1 -0.0 0.0 0.4 0.8 0.8 -0.1 0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.8 0.1 0.2 -0.2 -0.9 -0.3 0.2 0.3 0.2 0.0 -0.0 -0.1 0.1 0.1 0.2 -0.4 -0.2 0.1 0.0 0.2 0.1 0.1 0.5 -0.4 -0.1 -0.2 0.0 -0.4 -0.1 0.6 -0.3 0.3 -0.0 -0.0 0.1 0.0 0.0 0.2 -0.4 -0.0 -0.1 -0.1 0.5 0.7 0.0 0.1
Back pain experienced in last month 0.7 1.1 2.8 1.2 1.1 1.1 0.6 1.1 1.4 1.7 0.7 1.1 1.1 1.0 0.7 0.7 1.0 1.1 1.1 1.1 0.8 0.9 0.8 1.3 1.4 0.7 1.0 0.7 0.8 0.8 0.6 1.6 1.1 0.9 1.0 0.9 1.3 0.7 0.9 1.2 0.9 0.9 1.2 0.8 1.4 1.3 0.9 1.0
Mineral and other dietary supplements 0.1 0.1 0.6 -0.2 -0.3 -0.3 -0.4 -0.2 -0.2 -0.3 -0.4 -0.2 0.4 -0.4 -0.3 -0.3 -0.2 -0.1 -0.2 -0.2 -0.4 -0.2 -0.3 -0.5 -0.2 -0.8 -0.2 -0.5 -0.2 -0.3 -0.3 -0.1 -0.0 -0.2 -0.2 -0.0 0.2 -0.2 -0.3 -0.1 0.3 -0.2 -0.1 0.4 -0.2 0.0 -0.2 -0.4
Breast cancer (self-reported) 0.0 0.1 0.4 -0.1 0.1 0.2 0.1 0.0 -0.3 -0.1 0.2 -0.1 0.1 0.4 0.3 0.3 0.2 0.1 -0.1 0.1 0.1 0.2 0.2 -0.1 0.0 0.1 0.0 0.2 0.2 0.3 0.4 -0.7 0.6 0.3 0.1 0.2 0.1 0.3 0.4 0.0 -0.2 0.1 0.0 0.2 -0.0 0.0 0.2 -0.1
Asthma (self-reported) 0.3 0.5 1.2 0.7 0.9 0.6 0.2 0.6 0.7 0.6 0.8 0.8 1.1 0.9 0.8 0.8 0.7 0.7 0.7 0.7 0.8 0.9 0.8 0.2 0.5 0.9 0.7 0.7 0.8 0.8 0.7 0.8 0.5 0.9 0.7 0.7 0.8 0.8 0.9 0.6 0.1 0.8 0.6 0.6 0.5 0.5 0.6 0.7
Osteoporosis (self-reported) 0.1 0.1 0.7 -0.4 -0.2 0.1 0.4 -0.1 -0.4 0.1 0.1 -0.1 -0.2 -0.0 0.0 0.0 -0.1 -0.3 -0.3 -0.2 -0.2 -0.2 -0.0 -0.3 -0.2 -0.4 -0.2 -0.3 -0.1 0.1 0.0 -0.9 0.0 -0.1 -0.2 -0.2 -0.2 -0.0 -0.0 -0.3 0.2 -0.1 -0.5 -0.4 -0.2 -0.1 0.1 -0.3
Osteoarthritis (self-reported) 0.5 0.6 1.8 0.7 0.8 0.5 1.2 0.9 0.7 0.8 0.7 0.7 0.4 0.7 0.7 0.7 0.7 1.1 0.7 0.7 0.7 0.6 0.8 -0.8 0.5 0.4 0.7 1.0 0.7 1.3 0.8 0.4 0.9 0.4 0.7 0.9 0.7 0.7 1.2 0.7 0.4 0.7 0.6 0.6 0.5 1.3 1.0 0.6
Medication: Aspirin 0.5 0.7 2.7 -0.6 -0.9 -0.7 0.1 -0.5 -0.5 0.0 -0.8 -1.0 -1.6 -1.0 -0.8 -0.8 -0.9 -0.4 -0.6 -0.8 -0.5 -1.0 -0.8 -1.5 -1.0 -0.4 -0.6 -0.5 -0.9 -0.5 -0.6 -0.5 -0.7 -1.2 -0.8 -0.9 -0.5 -0.8 -0.6 -0.9 -0.0 -0.8 -0.7 -0.5 -1.1 -1.4 -0.7 -1.0
Medication: Gliclazide 2.3 2.6 3.8 -1.5 -1.7 -1.3 -1.3 -1.7 -1.4 -0.9 -1.9 -1.6 -1.2 -1.2 -2.0 -1.9 -1.9 -1.5 -1.6 -1.8 -1.6 -1.7 -1.9 -0.6 -1.6 -1.3 -1.6 -1.7 -1.9 -1.8 -1.9 -0.8 -1.4 -1.4 -1.7 -1.6 -1.5 -1.9 -1.7 -1.7 -1.6 -1.8 -1.7 -1.7 -1.7 -1.4 -1.8 -1.4
Illnesses of father: None of the above (group 1) 0.5 0.6 4.9 0.8 0.4 0.6 -0.2 0.4 0.8 -0.1 -0.2 1.3 2.2 2.2 -0.0 0.0 0.3 0.4 0.7 0.3 -0.0 0.5 0.1 1.8 1.0 1.0 0.6 0.3 0.4 -0.3 -0.2 1.4 0.5 0.6 0.7 0.1 0.9 -0.0 -0.2 0.5 -0.6 0.3 0.8 -0.3 1.0 -0.1 -0.3 1.0
Smoking status: Current 0.5 0.8 7.1 0.4 -0.2 0.0 -2.2 -0.9 0.5 0.4 -0.9 0.1 0.0 -0.3 -0.9 -0.8 -0.5 -0.1 -0.1 -0.3 -0.4 0.1 -0.8 2.7 0.7 0.1 -0.3 -0.5 -0.6 -1.7 -1.2 1.9 -0.4 -0.0 -0.1 -0.8 -0.4 -0.9 -1.3 0.0 -1.9 -0.5 0.0 -0.8 0.6 -0.3 -1.2 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.1 0.7 0.1 -0.2 0.1 0.5 0.2 -0.0 -0.8 -0.5 -0.2 0.2 -0.4 -0.5 -0.5 -0.4 0.5 0.2 -0.3 -0.1 -0.3 -0.5 0.4 0.0 0.3 0.1 0.4 -0.4 -0.2 -0.5 -0.8 -0.5 -0.1 -0.0 -0.1 -0.1 -0.5 -0.4 -0.1 -0.4 -0.2 0.2 -0.2 -0.1 -0.3 -0.6 0.1
Whole body water mass 0.7 4.0 9.4 2.3 2.0 2.1 1.4 2.1 2.2 2.3 1.4 1.6 0.9 1.6 1.7 1.8 1.9 3.1 2.3 2.0 2.0 2.1 1.8 1.1 2.2 2.7 2.2 2.4 1.7 2.0 1.8 1.9 2.2 1.2 2.2 2.2 1.7 1.8 2.1 2.0 0.1 2.0 2.2 2.4 2.0 2.2 1.8 2.3
Leg predicted mass (right) 0.7 4.0 8.8 2.2 2.0 2.0 1.6 2.2 2.1 2.3 1.4 1.6 1.1 2.0 1.8 1.8 1.9 3.0 2.3 2.0 2.0 2.0 1.9 0.8 2.0 2.6 2.1 2.3 1.8 2.3 1.9 1.8 2.1 1.2 2.1 2.3 1.9 1.9 2.3 2.0 0.5 2.0 2.1 2.5 1.9 2.1 1.9 2.1
Arm fat mass (left) 0.3 1.3 3.2 1.3 1.1 1.1 0.9 1.2 1.2 0.7 0.6 0.9 0.5 1.1 0.9 0.9 1.0 1.8 1.4 1.1 1.0 1.1 0.9 -1.1 1.1 1.8 1.3 1.4 0.9 1.3 1.0 0.7 1.5 0.5 1.2 1.2 1.0 1.0 1.1 1.2 0.3 1.1 1.3 1.5 1.1 1.3 1.1 1.2
Number of self-reported non-cancer illnesses 0.6 1.0 5.9 -1.1 -0.9 -1.1 0.7 -0.5 -1.0 -0.6 -0.8 -1.2 -1.4 -0.9 -0.7 -0.7 -1.0 -0.9 -0.8 -0.9 -0.8 -1.2 -0.7 -2.4 -1.5 -1.0 -0.8 -0.6 -0.9 -0.0 -0.5 -1.6 -1.0 -1.2 -1.1 -1.1 -0.8 -0.7 -0.6 -1.1 0.9 -0.8 -1.0 -0.8 -1.4 -0.8 -0.4 -1.5
Average weekly champagne plus white wine intake 0.4 0.6 1.8 1.0 0.6 0.9 0.3 0.7 0.9 0.1 0.4 0.9 0.7 1.4 0.3 0.4 0.5 0.8 1.0 0.6 0.5 0.7 0.4 1.3 1.2 1.1 1.0 1.0 0.5 0.1 0.3 0.3 0.8 0.5 0.9 0.5 0.7 0.3 0.0 0.8 0.1 0.7 0.9 0.5 1.3 1.1 0.3 1.0
Miserableness 0.3 0.5 1.9 -0.2 -0.6 -0.5 0.4 0.0 -0.1 -0.7 -1.4 -1.0 -0.8 -0.7 -1.1 -1.1 -0.8 -0.2 -0.2 -0.7 -0.6 -0.9 -1.0 0.4 0.0 -0.2 -0.4 -0.1 -1.1 -0.5 -1.1 -0.2 -0.6 -1.4 -0.7 -1.1 -0.6 -1.1 -0.7 -0.6 -0.6 -0.7 -0.2 -0.9 -0.0 0.1 -1.0 -0.8
Guilty feelings 0.9 1.3 2.5 -1.0 -1.1 -0.7 0.2 -0.5 -0.9 -0.9 -1.6 -1.4 -1.0 -1.5 -1.5 -1.5 -1.3 -0.7 -0.9 -1.3 -1.0 -1.6 -1.4 -0.8 -1.0 -0.9 -1.0 -0.9 -1.5 -1.1 -1.4 -1.1 -1.2 -1.2 -1.2 -1.1 -1.0 -1.5 -1.0 -1.3 -0.8 -1.3 -0.9 -1.2 -0.9 -0.5 -1.3 -1.4
Wears glasses or contact lenses 0.1 0.1 0.8 -0.1 0.1 -0.3 -0.9 -0.5 -0.1 -0.2 -0.0 -0.3 0.4 -0.5 0.0 0.0 0.1 -0.1 -0.3 0.0 -0.0 0.1 0.0 -0.4 0.3 -0.9 -0.2 -0.2 -0.1 -0.7 -0.2 0.2 -0.4 0.3 -0.1 0.1 -0.5 0.0 -0.1 0.1 -0.8 -0.1 -0.1 0.0 0.3 0.7 -0.0 0.2
Ever taken oral contraceptive pill 0.4 0.4 3.4 0.6 0.3 0.6 1.2 1.2 0.6 -0.0 0.1 1.0 1.6 0.7 0.1 0.2 0.1 0.3 0.7 0.2 0.6 0.0 0.2 1.8 0.1 0.8 0.6 0.5 0.5 0.7 0.1 0.5 0.3 0.2 0.4 -0.0 1.1 0.1 0.4 0.1 1.0 0.4 0.7 0.2 0.0 -0.7 -0.1 0.0
Hearing aid user 0.5 0.6 2.1 0.5 0.7 0.7 1.2 1.2 0.6 0.7 0.6 0.2 -0.3 0.1 0.8 0.8 0.6 1.2 0.7 0.7 0.9 0.4 0.9 -1.0 -0.1 0.3 0.8 1.1 0.7 1.3 1.1 -0.1 0.6 0.7 0.6 1.0 0.7 0.9 1.4 0.5 0.9 0.8 0.8 1.2 -0.2 -0.1 0.9 0.3
Mother’s age at death 0.1 0.2 1.1 0.0 0.3 -0.0 0.5 0.2 -0.0 -0.1 0.4 0.3 0.4 0.5 0.6 0.6 0.4 -0.1 0.1 0.4 0.2 0.4 0.6 -1.1 -0.0 0.3 0.2 0.3 0.6 0.8 0.8 -0.2 0.4 0.1 0.3 0.3 0.4 0.7 0.5 0.2 0.7 0.4 0.1 0.4 -0.0 -0.3 0.6 0.1
Financial situation satisfaction 0.6 0.7 2.3 1.1 0.8 1.5 1.2 1.3 1.2 0.7 0.2 0.7 0.7 0.3 0.3 0.4 0.6 1.5 1.1 0.7 0.8 0.5 0.4 1.0 1.1 1.3 1.1 1.0 0.4 0.5 0.3 0.8 0.7 0.5 0.8 0.8 0.9 0.3 0.6 0.8 0.6 0.7 1.2 0.9 1.1 0.9 0.3 0.7
Tinnitus: Yes, now most or all of the time 0.7 0.9 2.5 0.8 0.9 1.1 0.8 0.8 0.9 1.3 0.7 0.7 0.1 0.3 0.7 0.7 0.8 1.4 0.8 0.9 1.2 0.8 0.8 -0.4 0.6 1.3 0.7 1.3 0.7 1.0 0.9 1.1 1.6 0.9 0.8 1.3 0.7 0.8 1.3 0.8 0.1 0.8 0.7 1.3 0.5 0.9 1.0 0.9
Commuting to job workplace: Public transport 0.4 0.5 4.2 0.5 0.5 0.9 1.1 0.7 0.6 0.4 0.6 0.5 0.3 0.1 0.7 0.7 0.5 0.5 0.6 0.6 0.9 0.4 0.7 0.8 0.3 0.1 0.6 0.4 0.6 0.7 0.8 0.2 0.3 0.5 0.6 0.3 0.8 0.7 0.3 0.7 2.1 0.7 0.6 0.8 0.5 0.9 0.9 0.2
Eye problems/disorders: Glaucoma 1.0 1.2 2.7 -0.9 -0.9 -1.3 -0.7 -0.9 -0.9 -0.6 -0.8 -1.4 -1.4 -1.6 -1.0 -1.0 -1.1 -1.1 -1.0 -1.1 -0.7 -1.0 -1.0 -0.9 -1.0 -1.2 -1.1 -1.0 -1.1 -0.8 -1.1 -0.6 -1.3 -1.3 -1.2 -1.3 -1.2 -1.0 -0.8 -1.2 -1.1 -1.0 -1.2 -1.3 -1.0 -1.4 -1.1 -1.0
Medication: Blood pressure 0.3 0.6 5.4 -0.3 -0.2 -0.2 1.9 0.7 -0.2 0.1 0.0 -0.2 -0.9 -1.3 0.1 0.1 -0.2 -0.2 0.1 -0.1 0.5 -0.6 0.1 -2.3 -1.0 -0.4 0.1 -0.1 -0.0 1.0 0.2 -1.1 -0.4 -0.6 -0.1 -0.3 0.3 0.1 0.3 -0.4 2.2 0.1 -0.0 0.2 -0.9 -1.3 0.3 -0.9
Pain type(s) experienced in last month: Hip pain 1.7 2.2 3.8 1.6 1.6 1.5 0.9 1.5 1.6 1.8 1.1 1.4 1.9 1.7 1.2 1.3 1.5 1.9 1.6 1.5 1.1 1.5 1.3 0.8 1.7 1.5 1.5 1.5 1.3 1.6 1.2 1.7 1.6 1.3 1.5 1.6 1.4 1.2 1.7 1.5 -0.1 1.4 1.6 1.3 1.6 2.0 1.3 1.6
Supplements: Fish oil (including cod liver oil) 0.4 0.5 1.7 0.8 0.7 0.7 1.3 1.0 0.8 0.5 0.7 0.4 0.3 0.8 0.7 0.7 0.6 0.5 0.8 0.5 0.8 0.5 0.7 1.2 0.7 0.9 0.8 1.1 0.6 1.0 0.6 0.2 0.3 0.6 0.7 0.2 0.3 0.6 0.7 0.5 0.4 0.7 0.6 -0.2 0.6 0.5 0.6 0.7
High cholesterol (Self-reported) 0.8 1.5 6.2 -1.3 -1.2 -1.2 1.0 -0.3 -1.3 -1.1 -0.8 -1.3 -1.1 -1.3 -0.7 -0.7 -1.2 -1.2 -0.9 -1.1 -0.7 -1.5 -0.8 -2.5 -1.9 -0.9 -0.8 -0.9 -0.9 0.0 -0.4 -2.5 -1.0 -1.7 -1.1 -1.1 -0.7 -0.7 -0.6 -1.4 1.4 -0.8 -1.1 -0.9 -1.9 -1.9 -0.5 -1.8
Medication: Bendroflumethiazide 0.1 0.1 0.8 0.1 -0.0 -0.0 0.9 0.5 0.2 0.0 -0.2 -0.3 -0.5 -0.7 -0.2 -0.1 -0.1 0.6 0.2 -0.0 0.2 -0.2 -0.1 -0.9 0.0 -0.1 0.2 0.3 -0.2 0.4 -0.2 -0.4 -0.2 -0.3 0.0 -0.1 0.1 -0.2 0.1 -0.0 0.2 -0.0 0.4 0.1 -0.1 0.1 -0.2 -0.2
Medication: Paracetamol 0.8 1.3 2.6 1.3 1.1 1.4 0.3 0.8 1.3 1.6 0.9 1.3 0.6 1.4 1.0 1.0 1.2 1.1 1.1 1.3 1.1 1.3 1.0 0.2 1.5 1.3 1.1 0.9 1.1 0.6 1.1 1.4 1.2 0.9 1.2 0.9 1.4 1.0 0.9 1.4 0.6 1.1 1.3 1.2 1.6 1.5 1.1 1.3
Medication: Lisinopril 0.4 0.6 6.7 -0.2 -0.1 0.3 2.6 1.0 -0.3 -0.8 0.0 -0.1 -0.5 0.5 0.2 0.2 0.0 0.8 0.3 0.1 0.5 -0.4 0.2 -1.4 -0.6 0.5 0.3 0.6 0.1 1.3 0.5 -1.9 -0.1 -0.6 0.1 0.1 0.4 0.3 0.7 -0.2 1.8 0.3 0.1 0.6 -0.5 -0.5 0.5 -0.8
Medication: Atorvastatin 2.2 2.7 11.9 -2.1 -1.8 -1.6 -0.1 -1.4 -2.0 -1.2 -1.4 -2.0 -2.3 -2.1 -1.2 -1.3 -1.5 -1.1 -1.9 -1.5 -0.9 -1.8 -1.2 -3.4 -2.5 -1.3 -1.8 -1.2 -1.5 -0.4 -0.9 -2.2 -1.2 -1.8 -1.9 -1.0 -1.6 -1.1 -0.4 -1.8 -0.3 -1.5 -2.1 -0.9 -2.5 -1.7 -0.8 -2.2
Illnesses of father: High blood pressure 0.8 1.0 2.9 -1.0 -0.9 -1.2 0.1 -0.6 -1.0 -1.2 -0.8 -1.4 -1.4 -1.4 -0.8 -0.9 -1.0 -0.7 -0.8 -1.0 -0.7 -1.1 -0.9 -1.7 -1.1 -0.5 -0.8 -0.6 -1.0 -0.4 -0.7 -1.7 -1.1 -1.5 -1.0 -1.0 -1.0 -0.9 -0.9 -1.0 -0.1 -0.9 -0.9 -0.9 -1.1 -0.8 -0.8 -1.2
Alcohol drinker status: Never 0.4 0.5 3.2 -1.0 -0.7 -0.3 0.9 -0.4 -0.9 -0.1 -0.5 -0.6 -0.3 0.3 -0.5 -0.5 -0.6 -0.2 -0.7 -0.6 -0.8 -0.9 -0.6 -1.8 -1.3 0.1 -0.7 -0.5 -0.5 0.1 -0.2 -1.1 -0.5 -0.6 -0.6 -0.1 -0.5 -0.5 -0.1 -0.8 0.4 -0.6 -0.9 -0.4 -1.3 -0.8 -0.2 -1.0
Ever smoked 1.5 2.6 9.7 2.1 1.7 1.7 -0.3 1.2 2.1 1.6 1.2 2.1 1.7 1.0 1.2 1.3 1.5 1.1 1.8 1.6 1.6 1.9 1.3 3.1 2.2 1.8 1.7 1.0 1.5 0.3 1.0 2.9 1.0 1.7 1.7 1.0 1.8 1.2 0.6 1.8 0.6 1.5 1.9 1.2 2.3 1.3 0.9 2.1
Basal metabolic rate 0.6 3.2 8.4 2.1 1.8 1.9 1.2 2.0 2.0 2.1 1.1 1.4 0.8 1.5 1.5 1.5 1.7 2.9 2.1 1.8 1.8 1.9 1.6 0.7 2.0 2.5 2.0 2.2 1.5 1.9 1.6 1.7 2.0 1.0 1.9 2.0 1.5 1.6 1.9 1.9 -0.1 1.8 2.0 2.2 1.8 2.0 1.5 2.1
Leg fat percentage (left) 0.1 0.2 5.2 0.3 0.2 0.3 0.3 0.3 0.2 -0.3 0.2 0.0 -0.4 0.0 0.1 0.2 0.2 0.7 0.4 0.2 0.2 0.3 0.1 -2.3 0.3 0.5 0.4 0.7 0.1 0.4 0.3 -0.3 0.6 -0.1 0.3 0.3 0.1 0.2 0.2 0.3 -0.0 0.3 0.3 0.5 0.3 0.4 0.3 0.3
Arm fat-free mass (left) 0.6 2.9 7.3 2.0 1.7 1.9 0.9 1.7 1.9 1.9 1.2 1.3 0.4 1.2 1.5 1.5 1.7 2.7 2.0 1.7 1.8 1.9 1.5 0.9 1.9 2.3 1.8 2.2 1.4 1.6 1.6 1.5 2.0 1.0 1.9 1.9 1.3 1.6 1.8 1.8 -0.2 1.7 1.8 2.1 1.8 1.8 1.5 2.0
Number of operations (self-reported) 0.1 0.1 0.5 0.4 0.3 -0.1 -0.4 0.0 0.2 0.4 0.2 -0.0 0.3 0.5 0.2 0.2 0.3 0.1 0.3 0.3 -0.1 0.5 0.2 -0.1 0.7 0.3 0.2 0.3 0.1 -0.1 0.2 0.4 0.2 0.2 0.2 0.2 -0.0 0.2 0.0 0.3 -0.6 0.2 0.2 -0.1 0.7 0.6 0.1 0.6
Average weekly beer plus cider intake 4.8 6.9 10.6 3.1 2.9 2.5 1.7 2.7 3.1 2.5 2.4 2.5 3.1 2.2 2.2 2.3 2.6 3.1 2.9 2.7 2.4 2.7 2.4 3.2 3.2 2.4 2.8 2.8 2.3 2.3 2.0 3.1 2.8 2.5 2.8 2.4 2.4 2.3 2.3 2.9 0.7 2.6 2.9 2.3 3.1 3.2 2.2 3.1
Irritability 4.9 8.3 12.7 -3.0 -3.0 -3.2 -1.6 -2.5 -2.8 -3.0 -3.0 -2.7 -2.6 -2.4 -2.9 -2.9 -3.1 -3.1 -2.9 -3.1 -2.9 -3.2 -2.9 -1.7 -3.2 -2.8 -3.0 -3.1 -2.9 -2.3 -3.0 -2.3 -3.0 -3.6 -3.1 -3.2 -2.4 -3.0 -2.6 -3.2 -1.3 -3.0 -2.8 -3.0 -3.2 -3.1 -2.9 -3.4
Risk taking 0.4 0.5 2.1 -0.0 -0.4 -0.5 -1.4 -0.7 0.0 -0.2 -0.9 -0.3 -0.5 -1.0 -0.9 -0.9 -0.7 -0.5 -0.3 -0.5 -0.6 -0.3 -0.8 1.0 0.2 -0.2 -0.4 -0.7 -0.7 -1.5 -1.1 0.7 -0.8 -0.5 -0.4 -1.1 -0.5 -0.9 -1.5 -0.2 -1.0 -0.7 -0.1 -1.0 0.2 0.2 -1.1 0.1
Ever had prostate specific antigen (PSA) test 0.2 0.3 2.1 -0.3 -0.4 -0.1 0.3 -0.1 -0.3 -0.8 -0.3 -0.9 -0.6 -0.6 -0.6 -0.5 -0.5 -0.0 -0.4 -0.5 -0.2 -0.6 -0.5 -0.2 -0.3 -1.4 -0.2 0.0 -0.7 -0.3 -0.5 -0.8 -0.7 -0.1 -0.4 -0.5 -0.8 -0.6 -0.4 -0.4 -0.5 -0.4 -0.3 -0.8 -0.3 0.3 -0.4 -0.3
Fractured/broken bones in last 5 years 1.6 2.1 5.6 -1.5 -1.2 -1.6 -2.4 -2.1 -1.5 -1.2 -1.1 -1.2 -1.2 -1.4 -1.2 -1.3 -1.2 -2.0 -1.8 -1.3 -1.2 -1.0 -1.3 -1.3 -1.1 -1.8 -1.7 -1.7 -1.2 -1.9 -1.4 -0.3 -1.7 -1.0 -1.5 -1.2 -1.4 -1.3 -1.6 -1.4 -1.5 -1.5 -1.6 -1.5 -1.1 -1.9 -1.5 -1.1
Age started oral contraceptive pill 0.2 0.3 2.0 0.0 0.3 0.2 0.6 0.5 -0.2 -0.2 0.7 0.9 1.3 0.3 0.7 0.7 0.4 -0.2 0.4 0.3 0.3 0.4 0.6 -0.2 0.0 0.4 0.3 -0.1 0.8 0.6 0.6 -0.8 0.5 0.4 0.4 0.2 0.9 0.7 0.3 0.2 1.4 0.5 0.3 0.6 0.1 -1.0 0.5 -0.1
Diastolic blood pressure, automated reading 2.5 7.8 10.8 -3.1 -2.9 -3.2 -1.7 -2.8 -3.0 -2.3 -2.4 -2.7 -3.1 -2.8 -2.5 -2.6 -2.8 -3.2 -3.1 -2.8 -2.7 -2.9 -2.6 -3.2 -3.2 -3.2 -3.0 -3.0 -2.6 -2.2 -2.3 -2.5 -2.8 -2.9 -2.9 -2.9 -2.7 -2.5 -2.5 -3.0 -1.0 -2.8 -3.1 -2.8 -3.1 -3.1 -2.4 -3.3
Ever depressed for a whole week 0.3 0.4 2.7 -0.6 -0.3 -0.3 -1.5 -1.0 -0.5 -0.0 -0.5 -0.6 -1.0 -0.7 -0.5 -0.5 -0.2 -0.6 -0.9 -0.4 -0.4 -0.3 -0.5 -0.4 0.0 -0.6 -0.8 -0.6 -0.5 -0.8 -0.4 0.5 0.1 -0.4 -0.7 -0.0 -0.8 -0.4 0.0 -0.3 -1.6 -0.6 -0.8 -0.4 -0.0 1.0 -0.3 -0.5
Unable to work because of sickness or disability 1.0 1.4 3.9 1.5 1.2 1.4 0.4 1.0 1.6 1.6 0.7 1.1 1.4 1.9 0.6 0.7 1.1 1.2 1.3 1.1 1.0 1.0 0.8 1.2 1.9 1.1 1.2 1.4 0.7 0.4 0.7 1.7 1.2 0.6 1.1 0.4 1.2 0.7 0.6 1.3 0.5 0.9 1.3 0.5 2.0 1.6 0.7 1.2
Commuting to job workplace: Cycle 0.1 0.1 0.4 0.2 -0.2 0.1 -0.1 0.1 0.1 -0.4 -0.5 -0.1 -0.0 -0.5 -0.3 -0.3 -0.3 -0.1 0.2 -0.2 0.0 -0.2 -0.3 0.6 0.0 0.5 0.1 -0.1 -0.2 -0.5 -0.4 -0.1 -0.4 -0.1 -0.1 -0.3 -0.1 -0.3 -0.6 -0.1 -0.2 -0.1 0.2 -0.4 0.0 0.3 -0.4 0.1
Myopia 0.2 0.3 2.1 -0.8 -0.5 -0.5 0.5 -0.1 -0.9 -0.5 -0.2 -0.6 -0.4 -0.2 -0.1 -0.2 -0.4 -0.2 -0.5 -0.5 -0.3 -0.5 -0.2 -0.9 -1.1 -0.0 -0.5 -0.1 -0.3 0.3 0.0 -1.4 -0.0 -0.5 -0.6 -0.2 -0.4 -0.1 0.2 -0.6 0.3 -0.3 -0.6 -0.2 -1.1 -0.5 -0.0 -0.9
Vascular/heart problems diagnosed by doctor 0.9 2.6 13.1 1.6 1.5 1.6 -1.1 0.7 1.5 0.8 1.1 1.9 2.4 2.0 1.1 1.2 1.6 1.1 1.3 1.5 1.1 2.0 1.2 3.6 2.3 1.3 1.3 1.3 1.5 0.0 0.8 2.3 1.6 2.1 1.6 1.6 1.5 1.2 0.9 1.8 -0.6 1.3 1.4 1.2 2.3 2.2 1.0 2.1
Cholesterol lowering medication 0.6 0.9 5.0 -0.9 -0.9 -0.6 1.0 -0.2 -0.9 -1.1 -0.7 -0.7 -0.8 -1.4 -0.6 -0.6 -1.0 -0.8 -0.6 -0.8 -0.3 -1.1 -0.6 -2.2 -1.6 -0.6 -0.6 -0.6 -0.7 -0.1 -0.4 -1.8 -0.7 -0.9 -0.7 -1.1 -0.5 -0.6 -0.7 -1.0 1.5 -0.6 -0.8 -0.4 -1.6 -1.2 -0.3 -1.4
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 2.0 -0.6 -0.8 -0.8 -0.5 -0.8 -0.5 -0.8 -1.0 -0.8 -0.4 -0.4 -0.9 -0.9 -0.9 -1.1 -0.6 -0.8 -0.9 -0.8 -0.8 -0.7 -0.7 -0.7 -0.7 -0.5 -0.9 -0.8 -0.9 -0.3 -0.7 -1.1 -0.9 -1.2 -0.6 -0.9 -0.9 -0.8 -0.4 -0.8 -0.6 -1.1 -0.6 -1.4 -0.9 -0.7
Pain experienced in last month 1.1 1.8 5.9 -1.6 -1.4 -1.4 0.4 -0.9 -1.7 -2.3 -0.5 -1.5 -1.3 -2.2 -0.7 -0.8 -1.2 -1.4 -1.3 -1.3 -0.7 -1.4 -0.9 -0.8 -2.0 -1.3 -1.2 -0.9 -1.0 -0.5 -0.6 -2.4 -1.2 -1.3 -1.3 -1.2 -1.4 -0.8 -0.9 -1.6 0.1 -1.1 -1.6 -0.9 -2.0 -2.0 -0.8 -1.6
Supplements: Calcium 0.2 0.2 2.4 -0.1 -0.0 -0.2 0.9 0.3 -0.1 0.2 0.2 -0.1 -0.7 -0.8 0.2 0.2 -0.0 -0.3 0.1 -0.0 0.2 -0.2 0.2 -1.5 -0.4 0.3 0.0 -0.2 0.2 0.5 0.4 -0.4 0.1 -0.3 -0.1 -0.3 -0.1 0.2 0.1 -0.1 1.2 0.1 -0.1 0.1 -0.3 -0.1 0.3 -0.4
Basal cell carcinoma (self-reported) 0.3 0.4 1.6 -0.4 -0.6 -0.6 -0.6 -0.4 -0.6 -1.2 -0.6 -0.6 -0.1 -0.4 -0.6 -0.6 -0.6 -0.3 -0.3 -0.6 -0.5 -0.4 -0.6 0.0 -0.4 -0.8 -0.4 -0.3 -0.6 -0.7 -0.7 -1.3 -0.7 -0.6 -0.5 -0.5 -0.8 -0.6 -0.9 -0.5 -0.8 -0.5 -0.3 -0.6 -0.3 0.6 -0.7 -0.4
Heart attack/myocardial infarction (self-reported) 0.5 0.6 2.2 -0.9 -0.8 -0.8 -0.5 -1.0 -0.7 -0.1 -0.6 -1.1 -1.5 -1.5 -0.7 -0.8 -0.7 -0.3 -1.0 -0.7 -0.6 -0.8 -0.7 -1.2 -1.0 -0.6 -1.0 -0.9 -0.9 -0.4 -0.6 -0.0 -0.7 -0.9 -0.8 -0.1 -1.0 -0.7 -0.2 -0.7 -0.8 -0.8 -1.2 -0.2 -1.1 -0.5 -0.3 -0.7
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.6 0.5 0.2 0.4 0.1 0.3 0.6 0.7 -0.3 -0.1 0.2 0.0 -0.2 -0.2 -0.0 0.4 0.4 0.0 0.2 0.0 -0.1 0.6 0.4 0.3 0.3 0.2 -0.1 -0.2 -0.3 0.8 0.2 0.1 0.2 -0.1 0.1 -0.2 -0.1 0.2 -0.5 0.0 0.5 -0.3 0.4 0.3 -0.3 0.3
Heart disease (siblings) 0.2 0.3 3.1 0.1 0.3 0.1 -0.9 -0.4 0.1 0.5 0.1 -0.4 -0.6 -1.2 0.1 0.1 0.4 0.7 -0.2 0.3 0.3 0.4 0.1 0.3 0.2 -0.1 -0.1 0.3 -0.1 0.2 0.1 0.8 0.2 0.4 0.0 0.9 -0.5 0.1 0.8 0.2 -1.8 -0.0 -0.1 0.5 0.1 1.3 0.3 0.5
Alcohol drinker status: Previous 0.1 0.2 0.8 0.0 0.3 0.3 0.2 0.1 0.0 0.2 0.6 0.2 0.3 -0.1 0.5 0.4 0.5 0.1 0.1 0.4 0.5 0.3 0.5 -0.3 0.1 0.2 0.1 0.3 0.4 0.6 0.5 0.0 0.6 0.3 0.2 0.6 0.1 0.5 0.7 0.4 0.2 0.3 -0.1 0.6 0.1 0.9 0.8 0.2
Pack years of smoking 0.3 0.5 2.4 -0.8 -0.6 -0.5 -1.5 -1.3 -0.8 -0.2 -0.4 -0.8 -1.1 -1.3 -0.4 -0.4 -0.4 -0.8 -1.0 -0.4 -0.4 -0.3 -0.4 -1.1 -0.4 -1.1 -0.9 -0.7 -0.5 -1.1 -0.4 -0.1 -0.4 0.1 -0.6 -0.4 -0.8 -0.3 -0.4 -0.5 -0.7 -0.7 -1.0 0.0 -0.4 -0.6 -0.3 -0.6
Impedance of whole body 1.0 4.9 8.4 -2.3 -2.2 -2.1 -1.6 -2.1 -2.2 -2.4 -2.1 -2.0 -1.1 -2.1 -2.3 -2.3 -2.4 -2.9 -2.3 -2.4 -2.2 -2.5 -2.3 -0.5 -2.3 -2.4 -2.4 -2.7 -2.2 -2.2 -2.4 -1.8 -2.2 -1.6 -2.5 -2.6 -1.8 -2.4 -2.4 -2.3 -1.0 -2.4 -2.2 -2.7 -2.2 -1.9 -2.4 -2.5
Leg fat mass (left) 0.1 0.3 2.6 0.6 0.4 0.4 0.1 0.5 0.5 0.1 0.2 0.1 -0.4 0.3 0.3 0.3 0.4 1.1 0.6 0.5 0.4 0.6 0.3 -1.6 0.5 0.7 0.6 0.8 0.3 0.5 0.5 0.0 0.7 -0.1 0.5 0.6 0.2 0.4 0.5 0.6 -0.3 0.5 0.6 0.8 0.5 1.0 0.5 0.6
Arm predicted mass (left) 0.5 2.7 7.2 1.9 1.7 1.8 0.9 1.7 1.8 1.9 1.1 1.2 0.4 1.1 1.3 1.4 1.6 2.7 1.9 1.6 1.7 1.8 1.4 0.7 1.9 2.3 1.8 2.1 1.3 1.5 1.4 1.6 1.9 0.9 1.8 1.8 1.2 1.4 1.7 1.7 -0.3 1.6 1.8 2.0 1.8 1.8 1.4 2.0