Hub : Genes

INCENP

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.2262	0.0911	8.3e-03	0.053	NA	0.006	NA	0.027	5.7e-03	NA	1.8e-01	NA	3.8e-02
2	GTEx	Artery Aorta	0.1560	0.0550	1.5e-03	0.123	NA	0.045	NA	0.090	2.9e-07	NA	1.6e-03	NA	1.1e-05
3	GTEx	Artery Tibial	0.1855	0.0528	8.0e-06	0.158	NA	0.161	NA	0.155	2.1e-12	NA	1.2e-12	NA	3.6e-12
4	GTEx	Breast Mammary Tissue	0.2730	0.0700	1.9e-04	0.034	NA	0.089	NA	0.069	7.2e-03	NA	2.7e-05	NA	2.1e-04
5	GTEx	Breast Mammary Tissue (Female)	0.3203	0.1058	5.9e-03	-0.007	NA	0.082	NA	0.064	6.2e-01	NA	1.9e-03	NA	5.8e-03
6	GTEx	Esophagus Mucosa	0.2920	0.0570	3.4e-11	0.191	NA	0.255	NA	0.245	7.9e-13	NA	3.9e-17	NA	1.8e-16
7	GTEx	Esophagus Muscularis	0.1410	0.0490	1.6e-03	0.067	NA	0.102	NA	0.092	7.0e-05	NA	9.0e-07	NA	3.3e-06
8	GTEx	Heart Atrial Appendage	0.2390	0.0710	8.9e-05	0.048	NA	0.112	NA	0.109	3.3e-03	NA	1.0e-05	NA	1.4e-05
9	GTEx	Nerve Tibial	0.2199	0.0624	1.1e-04	0.108	NA	0.146	NA	0.132	4.7e-08	NA	1.6e-10	NA	1.3e-09
10	GTEx	Thyroid	0.2390	0.0580	4.2e-09	0.087	NA	0.209	NA	0.210	3.4e-07	NA	6.7e-16	NA	5.5e-16
11	METSIM	Adipose	0.0509	0.0210	3.3e-03	0.004	0.004	0.001	0.003	0.000	6.5e-02	6.9e-02	2.4e-01	0.1100	3.3e-01
12	ROSMAP	Brain Pre-frontal Cortex	0.0539	0.0229	3.5e-03	0.007	0.012	0.018	0.017	0.019	4.1e-02	8.4e-03	1.9e-03	0.0023	1.6e-03
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.1354	0.0639	6.6e-04	0.016	0.036	0.028	NA	0.021	6.0e-03	5.7e-05	3.6e-04	NA	1.9e-03
14	TCGA	Liver Hepatocellular Carcinoma	0.1890	0.0850	4.8e-03	0.030	0.060	0.080	NA	0.068	1.4e-02	8.7e-04	1.3e-04	NA	4.0e-04
15	TCGA	Prostate Adenocarcinoma	0.2099	0.0657	5.1e-06	0.087	0.074	0.094	NA	0.087	2.1e-09	3.4e-08	4.9e-10	NA	2.1e-09
16	TCGA	Thyroid Carcinoma	0.5320	0.0970	5.6e-17	0.110	0.206	0.227	NA	0.224	8.6e-11	8.3e-20	7.3e-22	NA	1.6e-21

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Bipolar Disorder (2018)	1.3	2.1	6.8	-2.6	0.3	0.1	-2.5	-2.3	2.1	-0.3	-1.6	-0.2	1.3	-0.5	-0.4	-1.3	1.9	0.1	1.1
Bipolar Disorder or Schizophrenia	0.8	1.8	13.3	-3.6	-0.1	0.5	-2.4	-2.1	0.7	0.3	-1.2	-0.3	1.1	0.1	-0.3	-1.2	0.5	-0.3	1.0
Depressed Affect (Nagel 2018)	0.2	0.5	4.5	-2.1	-0.3	0.0	-0.6	-1.2	0.0	-0.6	0.1	0.3	-0.0	-0.7	-0.0	-0.8	0.4	-0.3	0.0
Depression (Nagel 2018)	0.3	0.5	2.1	-1.5	-0.4	-0.7	-0.7	-1.2	0.1	-0.4	-0.4	-0.6	-0.1	0.4	-0.9	-0.9	-0.3	-0.9	-0.0
Intelligence (Savage-Jansen 2018)	0.9	2.8	9.3	-1.2	-1.3	-2.3	-2.0	-0.4	0.6	-1.0	-2.4	-2.1	0.5	-1.5	-3.0	-0.8	-1.2	-2.5	0.4
Neuroticism (Nagel 2018)	0.7	1.6	10.7	-3.3	-0.7	-0.8	-1.0	-1.8	1.3	-1.5	-1.0	-0.6	0.0	-0.6	-0.8	-1.4	0.9	-0.7	-0.1
Schizophrenia (2018)	0.3	0.7	6.3	-2.5	-0.3	0.6	-1.0	-0.7	-0.9	0.6	-0.2	-0.2	0.3	0.5	-0.1	-0.5	-0.8	-0.5	0.3
Schizophrenia vs Biploar Disorder	0.9	1.2	4.9	2.2	-0.5	-0.4	1.2	0.7	-2.2	0.4	1.1	-0.2	-1.4	0.3	0.4	0.2	-1.6	-0.2	-0.9
Worry (Nagel 2018)	1.3	2.7	7.1	-2.7	-1.2	-1.3	-1.2	-2.0	1.9	-2.3	-2.1	-1.3	-0.8	-0.6	-1.7	-2.4	0.8	-0.9	-1.1
Alzheimer’s Disease (in mother)	0.7	0.9	3.5	-0.7	0.3	0.0	0.0	-0.8	-0.0	1.4	-0.6	1.2	1.6	-0.0	1.2	1.0	0.2	-0.1	1.9
Alzheimer’s Disease (in father)	1.6	1.8	4.6	-1.4	1.9	1.7	-0.2	-0.9	0.7	1.3	0.4	1.4	2.1	-0.1	1.1	0.2	1.5	1.6	2.1
Alzheimer’s Disease (including proxy)	0.7	1.0	3.3	-0.4	1.0	0.6	-0.0	-0.5	0.3	1.5	-0.7	1.4	1.7	-0.2	1.0	0.9	0.6	0.6	1.8
Crohns Disease (2017)	0.6	1.4	3.4	-1.5	1.0	1.9	-0.2	-0.5	-1.8	1.5	1.2	1.4	-1.1	1.7	0.8	0.9	0.3	0.9	-0.4
Irritable Bowel Disease (IBD)	0.7	1.6	5.2	-2.3	0.6	1.7	0.6	0.7	-2.3	1.0	1.1	1.2	-0.3	1.7	1.5	1.0	-0.3	0.4	0.6
Ulcerative Colitis (UC)	0.5	1.0	5.7	-2.4	-0.5	0.2	0.2	0.5	-1.1	-0.2	-0.2	-0.1	1.1	0.8	1.3	0.3	-0.8	-0.8	1.7
Major Depression (MDD)	0.8	1.0	7.1	-2.7	-0.6	0.6	-0.7	-1.3	-1.5	-0.6	-0.3	-0.1	-1.0	-0.6	-0.1	-0.3	-0.9	-0.6	-0.6
Reaction Time	0.4	0.7	5.5	-2.3	0.6	0.8	0.9	0.5	-1.2	0.2	0.9	0.7	-0.3	-0.0	0.4	0.2	-0.6	0.6	-0.7
Verbal and Numeric Reasoning (VNR)	0.9	2.1	8.1	-1.9	-0.4	-1.7	-1.7	-0.9	1.5	-0.1	-2.8	-1.1	1.0	-1.6	-2.4	-0.3	0.5	-1.5	0.7
Breast Cancer	3.1	7.5	20.2	1.6	1.3	3.3	4.0	2.5	-2.3	3.0	3.7	2.1	-0.3	4.3	4.5	2.2	-0.0	2.7	0.2
Ovarian Cancer	0.5	0.6	3.8	2.0	-0.0	0.5	1.0	0.0	-1.0	0.7	0.5	-0.2	-0.1	0.1	1.6	0.4	-0.7	0.4	0.2
Prostate Cancer	1.4	2.0	10.1	-1.1	0.2	-0.4	0.4	1.0	0.6	-1.4	0.1	-0.6	-2.7	-0.1	-2.9	0.3	0.3	0.2	-3.2
Age at First Birth	0.3	0.4	1.0	-0.7	0.9	0.5	-0.6	-0.9	0.5	-0.2	-0.1	0.3	-0.4	-0.9	-0.4	0.4	1.0	0.7	-0.5
Bipolar Disorder (2011)	1.9	1.8	7.3	-2.7	-1.3	-0.7	-2.1	-1.7	-0.8	-0.1	-1.5	-0.9	0.3	-0.6	-0.6	-0.8	-1.9	-1.8	0.5
Body Mass Index (BMI) (2010)	1.1	1.5	4.1	1.2	0.0	0.5	1.4	1.8	-2.0	2.0	0.6	1.0	-0.5	1.6	1.1	0.3	-1.6	-0.0	-0.3
Coronary Artery Disease (CAD)	0.6	0.7	4.3	1.0	-0.9	-0.3	0.3	0.1	-0.3	0.3	-0.0	-0.7	0.7	2.1	1.3	0.1	-0.8	-0.6	1.1
Crohns Disease (2012)	1.8	2.9	9.6	-1.4	2.2	3.1	0.5	-0.1	-1.3	2.0	1.8	2.4	-0.2	1.9	1.8	1.4	1.0	2.2	0.2
Mean Putamen Volume	1.3	1.4	3.5	-1.8	1.2	1.8	0.3	-0.3	-1.3	0.7	1.9	1.7	-1.4	-0.6	0.5	1.0	-0.1	1.2	-1.2
Fasting Glucose	3.2	3.8	10.8	1.9	-1.7	-3.2	-1.9	-0.4	3.3	-1.7	-2.5	-2.5	1.0	-1.4	-1.5	-2.5	1.0	-1.3	0.8
HbA1C	1.8	2.0	5.1	-1.4	-2.3	-1.8	-1.5	-0.6	-0.1	-1.6	-1.8	-1.6	0.5	-0.1	-0.3	-1.9	-1.6	-1.9	0.6
HDL Cholesterol	1.8	3.0	11.2	3.3	-1.1	-3.2	-1.4	-0.6	2.2	-1.5	-1.5	-1.9	0.7	-0.9	-1.7	-2.0	0.1	-1.3	-0.1
LDL Cholesterol	4.4	7.0	32.5	5.7	-3.2	-3.8	-1.1	0.4	0.9	-2.5	-1.9	-3.0	-1.4	-3.0	-2.0	-2.5	-1.8	-2.9	-1.3
Lupus	1.1	1.7	7.7	-0.4	1.0	1.3	0.9	0.3	-0.7	0.6	1.9	1.3	-2.2	1.1	-0.4	0.7	0.5	1.4	-2.8
Neuroticism (2016)	0.4	0.6	5.4	-2.3	0.6	0.6	-0.6	-1.1	-0.2	0.4	0.3	0.8	-0.7	0.5	-0.5	0.1	0.4	0.4	-0.4
Primary Biliary Cirrhosis	0.3	0.4	1.9	-0.2	0.0	0.1	-1.4	-1.3	1.2	-0.6	-0.0	0.0	0.3	-0.7	-0.5	-0.7	0.5	-0.0	0.0
Rheumatoid Arthritis	1.4	1.9	5.3	1.5	0.9	1.4	2.3	1.9	0.5	1.7	1.1	1.0	-0.3	2.1	1.6	0.0	1.3	1.6	-0.3
Schizophrenia (2014)	0.6	1.2	7.2	-2.7	-0.9	0.4	-1.6	-1.1	-1.4	0.5	-0.6	-0.6	-0.2	1.1	0.0	-0.7	-1.5	-1.0	0.2
Triglycerides	0.4	0.7	3.9	-2.0	0.1	1.7	-0.5	-0.8	-1.2	-0.2	0.7	0.1	-1.1	-0.0	-0.0	-0.1	-0.3	0.2	-0.3
Type 2 Diabetes (T2D) (2012)	0.7	0.8	3.6	1.9	0.4	-0.4	0.1	0.3	1.1	-0.1	-0.5	-0.1	1.7	-0.2	0.4	-1.2	1.5	0.6	1.0
Ulcerative Colitis	0.6	0.9	2.6	-1.6	0.4	1.4	0.8	1.0	-1.1	0.8	0.9	1.1	0.2	1.1	1.1	0.8	-0.2	0.3	0.9
Blood Eosinophil Count	1.0	7.6	46.4	6.8	-2.2	-3.9	-0.7	0.1	2.5	-2.5	-2.8	-2.3	1.1	-3.2	-0.6	-3.5	0.3	-2.0	0.8
Blood Platelet Count	1.1	13.1	61.3	-7.8	1.2	5.5	0.3	0.1	-6.4	3.4	3.2	3.5	-1.2	2.8	2.4	4.1	-3.0	0.8	-0.1
Blood Red Count	0.4	4.2	45.0	-6.7	0.8	2.1	-0.5	-2.0	-0.8	0.8	0.1	0.9	-1.3	2.1	-1.0	1.1	1.3	0.5	-1.1
Blood White Count	0.7	5.4	40.1	6.3	-1.6	-1.6	0.9	1.5	1.9	-0.1	-2.7	-1.1	2.5	0.1	1.1	-3.1	0.1	-1.5	2.5
Heel T-Score	0.8	6.0	13.9	-3.6	-2.9	-2.0	-1.9	-2.0	0.5	-0.8	-0.7	-3.3	-3.7	3.2	-3.0	-0.9	-1.4	-1.7	-3.6
BMI	0.3	1.5	6.5	1.6	-1.1	-0.1	-0.7	-1.2	-0.6	1.2	-0.8	-0.3	2.2	-0.1	1.7	-0.2	-0.6	-1.0	2.5
Height	0.2	3.3	14.7	3.8	-1.0	-3.1	0.6	2.2	2.4	-1.4	-1.7	-1.6	-1.1	-1.8	-0.9	-1.3	1.0	-0.6	-1.2
Waist Hip Ratio (WHR)	0.7	3.3	16.9	0.9	0.8	0.1	0.5	-0.6	0.9	-4.0	3.6	-0.4	0.0	-4.1	-0.2	-0.8	1.5	1.0	-0.1
Systolic Blood Pressure	0.3	1.7	4.8	-0.8	-0.9	-1.4	-1.1	0.7	-0.4	-1.6	0.7	-1.3	-2.0	0.5	-2.2	-1.0	-0.7	-1.4	-2.0
Smoking Status	0.2	0.4	2.2	1.5	-0.6	0.2	0.0	-0.5	-0.5	1.1	0.1	-0.0	-0.5	0.9	1.1	0.3	-0.4	-0.1	-0.1
Allergy or Eczema	0.1	0.4	1.0	0.0	-0.5	-0.9	0.5	0.9	0.9	-1.0	-0.4	-0.1	-0.4	0.9	-0.1	-0.7	0.1	-0.2	-0.4
Cardiovascular Disease	0.1	0.4	2.6	-0.1	-0.6	-0.9	-1.6	-0.3	0.1	-0.7	0.6	-0.4	-0.2	0.9	-0.4	-0.0	0.0	-0.5	-0.2
Hypothyroidism (self reported)	0.7	1.6	6.6	2.4	-0.8	-2.6	-0.0	0.7	1.2	-1.7	-1.0	-1.2	0.2	-1.6	-1.0	-0.5	-0.7	-1.1	0.0
Respiratory disease	1.9	4.3	13.2	2.3	-2.1	-3.4	-1.6	-1.0	2.5	-2.3	-2.2	-3.6	-0.8	-0.1	-2.1	-2.4	0.4	-1.4	-1.2
Type 2 Diabetes (T2D) (2018)	0.6	1.2	3.0	1.6	-0.9	-1.7	-1.1	0.0	1.3	-1.7	-0.9	-1.5	0.8	-0.8	-0.8	-0.4	-0.1	-1.0	0.7
Lung FEV1/FVC ratio	0.8	4.1	9.0	-0.2	-1.6	-2.1	-2.2	-2.9	3.0	-2.7	-0.2	-1.5	2.9	-2.4	1.5	-1.6	1.5	-0.7	2.0
Lung FVC	0.5	2.7	19.2	-4.4	0.7	1.4	-0.4	-1.3	0.1	-2.7	-0.3	0.6	-0.7	-2.3	-0.5	0.8	0.7	1.1	-1.8
Neuroticism	0.7	1.6	17.6	-4.2	-0.7	-0.6	-0.8	-1.4	0.9	-1.1	-0.7	-0.8	-0.3	-0.4	-0.5	-1.0	0.5	-0.4	-0.6
Chronotype (morning person)	1.6	3.7	9.4	-0.0	3.0	2.3	1.4	1.1	0.3	3.1	1.1	3.0	1.3	1.1	1.5	1.9	1.8	2.9	1.2
Hair Pigment	0.1	2.5	8.1	-2.3	-1.2	-0.7	-0.3	-0.0	-2.8	1.6	-0.6	-0.8	-1.9	1.8	-0.5	1.2	-2.9	-1.0	-2.0
Tanning	0.1	0.7	2.5	0.0	-0.7	-0.9	-1.5	-1.6	0.8	-0.3	-1.3	-0.5	0.1	-0.6	-0.4	-1.2	0.1	-0.7	0.2
Hand grip strength (left)	0.3	0.7	1.6	-1.3	-1.1	-1.2	-0.2	-0.5	-0.2	-0.6	-0.6	-1.1	-0.3	-0.6	-1.2	-1.0	-0.7	-1.1	-0.6
Number of treatments/medications taken	0.6	1.1	3.3	1.8	0.7	0.7	0.9	1.3	-0.9	1.1	0.2	1.1	0.2	1.8	1.2	1.4	-0.4	0.7	0.4
Average weekly spirits intake	1.3	1.6	3.2	1.4	-0.6	-1.7	0.3	1.1	1.8	-1.5	-1.8	-1.3	1.3	-0.6	-1.4	-1.5	0.5	-1.2	1.0
Sensitivity / hurt feelings	0.4	0.7	6.6	-2.6	0.6	-0.0	-0.3	-0.7	0.7	0.4	-0.4	-0.0	0.6	-0.3	-0.2	-0.9	1.0	0.0	0.8
Frequency of depressed mood in last 2 weeks	0.7	1.0	5.1	-2.2	-0.6	-1.0	-1.1	-1.0	0.1	-1.3	-0.3	-0.8	-0.0	-0.5	-1.4	-1.2	-0.3	-1.1	0.1
Hearing difficulty/problems: Yes	0.7	1.1	3.9	-0.1	1.3	0.4	2.0	1.4	0.0	0.6	0.8	0.9	1.4	0.9	0.9	1.3	0.1	0.8	1.2
Relative age of first facial hair	0.2	0.3	1.9	-0.6	-0.2	0.2	0.3	-0.1	-1.4	0.2	-0.7	0.1	-0.1	-0.8	0.4	0.0	-1.1	-0.5	0.3
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	5.1	2.2	1.3	1.0	2.3	2.0	-0.1	1.5	0.6	1.4	0.6	2.1	0.9	1.6	0.1	0.8	0.8
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.2	-1.3	1.1	0.3	0.2	0.4	0.6	-1.0	0.1	0.5	-0.2	-1.5	-0.8	1.1	0.6	0.7	-0.5
Ever had hysterectomy (womb removed)	0.7	0.8	2.4	-1.1	-0.6	-1.0	-0.6	0.6	-0.4	-1.2	0.7	-0.7	-0.7	0.1	-1.1	0.4	-1.6	-1.1	-0.9
Systolic blood pressure, automated reading	0.4	1.0	4.0	0.2	-0.8	-0.9	-0.5	0.6	-1.7	-1.2	0.3	-0.5	-0.7	-0.3	-1.2	-0.6	-2.0	-1.7	-0.5
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	4.0	0.5	-1.4	-1.5	-1.4	-1.5	0.9	-2.0	-0.9	-1.6	0.6	-1.5	-0.6	-0.9	-0.6	-1.6	0.7
Angina	0.2	0.2	0.8	-0.1	0.5	0.2	0.2	0.9	-0.1	-0.1	0.6	0.5	0.6	0.1	-0.1	0.7	-0.5	-0.3	0.9
Medication for hormone replacement therapy	0.8	0.9	3.4	-0.2	-0.5	-0.8	0.4	0.8	0.8	-1.7	-0.8	-1.2	-0.3	-1.1	-1.4	-1.8	0.2	-0.6	-0.8
Vitamin and mineral supplements	1.7	2.4	6.1	1.0	1.6	1.7	1.6	1.9	-1.3	1.7	2.0	2.0	1.2	-0.0	1.4	2.5	-0.3	0.7	1.5
Supplements: Zinc	1.5	1.7	11.1	-0.8	-0.5	0.6	0.0	-0.2	-1.3	-0.3	1.0	-0.1	-3.0	0.1	-1.0	1.0	-0.7	0.5	-3.3
Medication: Co-codamol	1.3	1.5	4.5	-0.0	-1.2	-0.7	-1.1	-0.6	0.1	-0.8	-1.9	-0.8	1.9	-2.1	0.6	-0.7	-1.0	-1.4	2.1
Medication: Metformin	0.3	0.4	1.1	0.8	0.5	0.3	0.1	0.4	-0.6	-0.3	1.1	0.5	0.6	-0.0	1.0	1.0	-0.5	0.5	0.9
Diabetes (father)	0.5	0.6	2.1	-0.1	1.4	0.7	0.7	0.1	-0.2	0.6	0.4	1.0	0.7	-0.4	0.9	1.4	0.2	1.0	0.4
Diabetes (mother)	0.8	1.1	3.0	0.1	-0.2	-0.9	-1.0	-0.5	1.6	-1.7	-1.2	-0.9	1.1	-1.7	-0.5	-1.1	1.1	-0.3	0.8
Severe depression (siblings)	0.3	0.3	1.4	1.0	-0.1	-0.6	-0.1	-0.0	-0.2	-0.0	-0.3	-0.7	-0.5	-0.7	-1.2	-0.3	-0.7	-0.5	-0.2
Pack years adult smoking proportion	0.5	0.8	2.7	0.5	-1.5	-0.6	0.5	0.4	-1.3	-1.3	0.4	-0.8	-0.7	-0.5	0.4	-0.3	-1.6	-1.0	-0.8
Impedance of leg (right)	0.4	2.1	5.3	-1.3	0.1	-1.5	-1.0	0.9	1.8	-1.0	-1.2	-1.4	-2.1	2.0	-2.3	-0.9	0.9	0.2	-2.3
Leg fat-free mass (left)	0.3	1.6	6.5	2.5	-1.5	-0.7	-0.6	-0.9	-0.2	0.1	-0.6	-0.7	1.5	-2.1	1.4	-0.6	-0.6	-1.3	1.7
Trunk fat percentage	0.4	1.7	6.8	2.1	0.2	0.7	-0.3	0.3	-0.8	2.6	-0.3	0.9	1.7	1.6	1.4	1.0	0.2	-0.1	2.1
Hand grip strength (right)	0.1	0.3	2.4	-1.5	-0.6	-0.5	-0.2	-0.2	-0.4	0.2	0.1	-0.2	0.0	-0.3	0.5	-0.5	-0.3	-0.2	-0.2
Townsend deprivation index at recruitment	0.7	1.0	3.2	-1.8	0.9	1.4	-0.7	-0.6	-1.8	0.6	1.1	1.0	0.1	-0.7	0.2	1.2	-0.6	0.6	0.2
Current tobacco smoking	1.3	2.1	8.4	2.9	-0.9	0.2	1.7	1.3	-2.1	0.7	0.6	-0.3	-2.1	1.8	0.4	0.6	-1.8	-0.3	-1.7
Average weekly fortified wine intake	0.5	0.6	2.3	-0.5	0.6	0.4	-0.1	-0.4	1.1	0.9	-0.7	0.6	0.9	0.7	0.6	0.3	1.5	0.6	0.8
Maternal smoking around birth	0.6	0.9	2.6	-0.0	-1.1	-1.2	-1.0	-1.1	1.6	-0.4	-1.2	-1.5	-0.4	-0.1	-0.3	-1.0	0.7	-0.6	-0.4
Fed-up feelings	0.5	1.0	3.2	-1.0	-1.0	-1.0	-0.9	-1.0	0.1	-0.9	-1.5	-0.6	0.2	-1.8	-0.8	0.3	-0.8	-1.6	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	3.5	-1.1	-0.9	-1.5	-1.6	-1.9	0.1	-0.3	-1.2	-1.1	1.9	0.5	-0.7	-1.0	-0.8	-1.7	1.9
Relative age voice broke	1.2	1.9	4.5	-0.9	-1.8	-1.1	-1.0	-1.6	-0.8	-1.6	-1.1	-1.2	-1.2	-2.1	-1.2	-1.3	-1.5	-1.9	-0.9
Taking other prescription medications	0.5	0.8	4.3	2.1	0.7	0.4	1.3	1.0	-0.9	0.2	0.8	0.6	-0.1	0.1	0.8	1.4	-0.6	0.6	-0.2
Age when periods started (menarche)	0.4	0.9	2.9	-1.3	-1.4	-0.4	-0.9	-1.7	-0.5	-0.9	-1.3	-1.0	-0.3	-1.1	-0.3	-0.2	-1.2	-0.9	-0.2
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	6.7	-1.7	-0.1	-0.3	-0.4	-0.0	-1.0	-0.2	0.5	-0.0	-2.5	-0.9	-1.4	1.2	-1.6	-0.4	-2.6
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	6.1	-2.5	-1.1	-0.7	-1.1	-1.3	-0.7	-0.4	0.5	-0.9	-1.2	0.5	-0.9	-0.3	-1.7	-0.8	-1.1
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	3.4	-0.4	1.2	-0.0	-0.1	0.6	1.5	-0.1	0.9	0.0	0.5	-1.0	-1.1	-1.2	1.8	0.7	0.3
Qualifications: CSEs or equivalent	0.5	0.6	4.2	-0.1	0.7	0.3	0.0	0.0	2.0	-0.2	0.2	-0.0	-0.3	-0.3	0.1	-0.5	1.7	1.1	-0.2
Serious illness, injury or assault to yourself	0.3	0.3	1.6	1.2	-0.1	-0.3	-0.7	-1.0	-0.6	0.7	0.1	-0.1	-0.3	0.8	-0.4	-0.3	-0.6	-0.2	-0.5
High blood pressure	0.4	1.1	3.4	-0.3	1.5	1.2	-0.2	0.0	-0.9	1.5	1.6	1.9	0.5	1.3	0.5	1.2	0.4	0.9	0.6
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.7	-0.5	-0.6	-0.8	0.1	0.3	0.8	-0.8	-0.5	-0.2	0.5	0.5	0.2	-0.6	0.0	-0.4	0.5
Multivitamins +/- minerals	1.5	1.9	6.0	-1.3	-1.2	-1.5	-1.6	-1.8	1.4	-1.4	-1.5	-1.8	-0.9	-0.0	-1.0	-2.5	0.6	-0.3	-0.9
Stomach or abdominal pain in last month	2.9	3.6	8.2	-0.0	2.6	2.6	1.8	0.5	-0.4	2.3	2.1	2.9	1.2	0.9	2.7	1.0	1.8	2.5	1.5
Supplements: Glucosamine	0.4	0.5	1.9	-0.6	-0.3	-0.7	0.7	0.4	1.4	-0.8	-1.2	0.0	0.3	0.3	-1.1	-0.4	0.8	-0.4	-0.3
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	3.3	0.3	0.2	0.4	1.4	1.3	-1.8	0.6	1.1	0.7	1.1	0.5	1.1	1.5	-1.8	-0.3	1.1
Medication: Atenolol	1.0	1.3	4.6	-0.4	0.0	1.6	0.8	0.6	-2.1	0.9	1.7	1.0	0.4	1.5	1.7	0.7	-0.8	0.4	0.9
Medication: Levothyroxine sodium	0.6	1.0	3.3	1.5	-0.7	-1.1	0.3	0.2	-0.7	-0.6	-0.3	-0.2	1.5	-0.8	0.6	0.4	-1.8	-1.3	1.4
Sitting height	0.3	2.2	7.8	2.0	-1.8	-2.8	-0.8	0.1	1.9	-0.8	-2.5	-2.0	-0.4	-1.0	-0.4	-1.1	0.1	-1.3	-0.2
Chronic bronchitis/emphysema (father)	0.7	0.8	5.0	0.2	0.4	0.2	0.1	-0.5	0.3	2.2	-0.1	0.6	-0.9	2.0	-0.6	0.8	0.4	0.6	-0.7
High blood pressure (mother)	0.2	0.3	1.6	0.3	-0.2	-0.5	1.1	1.0	-0.5	0.3	-0.4	-0.1	-0.3	0.2	0.2	-1.3	-0.3	-0.3	-0.0
Body mass index (BMI)	0.4	1.8	8.9	1.2	-0.5	0.9	-0.5	-0.8	-1.6	1.3	0.0	0.7	2.5	-0.8	1.9	0.6	-0.8	-0.8	3.0
Impedance of leg (left)	0.4	1.8	6.6	-1.1	0.6	-0.7	-0.2	1.5	1.2	-0.6	-0.0	-0.7	-2.4	2.4	-1.9	-0.1	0.7	0.9	-2.6
Leg predicted mass (left)	0.3	1.6	6.5	2.6	-1.6	-0.8	-0.6	-0.9	-0.3	0.2	-0.6	-0.7	1.5	-2.1	1.4	-0.6	-0.7	-1.3	1.7
Trunk fat mass	0.4	1.6	5.4	2.2	-0.1	0.7	-0.3	0.1	-1.0	2.3	-0.2	0.9	1.8	0.6	1.8	0.9	-0.2	-0.2	2.3
Waist circumference	0.5	1.7	6.6	2.5	-0.1	0.6	0.2	0.1	-1.3	0.4	0.8	0.6	2.1	-1.0	2.1	0.8	-0.4	-0.2	2.6
Number of incorrect matches in round	0.6	1.0	4.5	-2.1	1.4	-0.0	0.0	0.1	0.0	0.8	1.3	0.6	-1.3	-0.1	-1.5	0.1	0.9	1.0	-1.2
Past tobacco smoking	0.2	0.3	1.6	-0.8	-0.2	0.3	0.8	0.7	-1.3	-0.2	0.3	-0.1	0.1	0.2	0.1	-0.1	-0.8	-0.1	-0.1
Alcohol usually taken with meals	1.0	1.6	5.3	-2.3	1.1	1.8	-0.3	-1.4	0.6	0.6	-0.4	1.7	1.1	-1.0	1.5	1.3	0.7	1.1	1.1
Nervous feelings	0.9	1.6	5.1	-2.3	-0.7	-0.8	-1.2	-2.1	0.1	-1.1	-0.9	-1.0	-1.0	-0.8	-1.4	-2.1	-0.2	-1.0	-1.0
Frequency of tenseness / restlessness in last 2 weeks	2.9	4.4	12.0	-3.0	-1.6	-2.2	-2.5	-3.5	2.2	-2.2	-2.1	-2.1	-0.2	-1.3	-2.5	-2.7	0.4	-1.7	-0.3
Hearing difficulty/problems with background noise	0.4	0.6	2.1	-1.3	0.6	-0.1	0.9	0.2	0.7	-0.4	0.1	0.2	1.4	-0.2	1.0	0.0	0.8	0.4	1.4
Hair/balding pattern: Pattern 2	0.3	0.4	1.2	-0.8	-0.5	-1.0	0.5	-0.3	0.6	-0.3	-0.3	-0.6	-0.8	0.3	-1.1	0.1	0.4	-0.3	-1.0
Had menopause	1.1	1.3	3.0	0.1	-0.9	-1.6	-1.7	-1.7	0.1	-1.0	-1.7	-1.0	0.4	-1.0	-1.0	-0.8	-1.1	-1.6	0.7
Had other major operations	0.6	0.8	2.9	-1.7	0.3	0.0	-0.8	-0.5	1.1	-0.6	-0.7	0.4	1.5	-1.0	0.1	-0.6	0.8	-0.2	1.3
Forced vital capacity (FVC)	0.6	2.4	8.6	-1.6	-0.8	-1.1	-1.0	-0.7	2.5	-2.9	-1.8	-1.5	-1.1	-2.0	-0.6	-1.3	1.5	0.2	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	6.9	-2.6	-0.8	-0.4	-0.0	-0.4	-1.2	-0.3	1.1	-0.7	-1.4	0.8	-0.8	-0.3	-1.6	-0.6	-0.9
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	4.3	-2.0	-0.3	-0.1	-1.1	-2.1	-0.0	0.6	0.1	-0.3	-0.6	0.3	-0.6	-1.0	0.6	-0.1	-0.7
Qualifications: None of the above	0.3	0.6	3.4	1.9	-0.4	0.1	-0.6	-0.1	-0.9	-0.1	-0.1	-0.2	-0.8	-1.7	0.6	0.6	-1.1	-0.1	-0.2
Financial difficulties in last 2 years	0.2	0.3	1.2	-0.0	-0.6	-0.4	-0.0	-0.1	-0.5	-0.4	0.6	-0.6	-0.5	0.5	0.1	-1.1	-0.5	-0.2	-0.4
Mouth/teeth dental problems	0.2	0.4	1.8	0.4	0.0	0.2	0.6	1.4	0.3	0.3	0.6	0.2	-0.5	0.7	0.6	0.9	0.1	0.6	-1.0
Heart attack	1.3	1.7	5.8	1.9	0.5	0.0	2.1	2.4	0.2	0.3	1.5	0.1	-1.7	1.6	-0.3	0.4	0.6	0.9	-1.9
Allergy	0.6	1.5	3.9	-1.7	1.1	2.0	-0.1	-0.8	-1.9	1.7	1.4	1.6	0.4	-0.3	0.9	1.5	-0.3	0.8	0.5
Pain all over the body in last month	1.6	1.7	6.2	1.5	-1.8	-1.4	-0.7	-0.6	0.9	-1.4	-1.3	-2.5	0.0	0.2	-0.5	-2.5	-0.4	-1.3	0.2
Diabetes (self-reported)	0.4	0.6	3.5	1.9	-0.4	-0.3	-0.5	0.5	-0.6	-1.1	0.9	-0.2	0.5	-0.3	0.4	0.6	-1.1	-0.5	0.9
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	3.7	0.2	-0.8	-1.2	-0.3	0.6	1.4	-1.9	-1.5	-0.9	-1.8	-0.6	-1.5	-1.1	0.6	-0.4	-1.6
Medication: Ramipril	1.5	1.9	6.2	-1.1	1.5	1.6	1.4	1.8	-1.5	1.5	1.7	2.5	-0.1	0.9	1.2	1.3	-0.1	1.1	0.1
Medication: Simvastatin	0.5	0.7	9.1	3.0	0.2	-0.3	-0.4	0.2	0.2	-0.7	0.6	0.1	0.0	-0.6	0.2	0.3	-0.1	0.2	0.4
Fluid intelligence score	0.3	0.6	2.0	-1.4	0.7	-0.3	0.5	0.5	0.1	1.1	-1.1	0.3	0.9	-0.4	-0.9	0.6	0.3	-0.2	0.9
Illnesses of siblings	0.9	1.2	4.4	0.9	-0.3	-0.4	-0.9	-0.7	1.1	-1.1	-1.6	-0.7	2.1	-1.3	-0.1	-1.0	-0.0	-0.8	1.9
Neuroticism score	1.7	3.5	14.5	-3.8	-1.3	-1.9	-1.9	-2.1	1.7	-1.9	-1.9	-1.9	-0.3	-1.4	-2.0	-2.1	0.2	-1.6	-0.4
Weight	0.3	1.3	5.3	2.3	-0.8	0.1	-0.4	-0.3	-0.9	1.1	-0.2	0.1	1.7	-1.2	1.7	0.2	-0.5	-0.7	2.2
Impedance of arm (right)	0.5	2.2	13.8	0.3	0.2	-1.4	-0.1	1.8	1.9	1.4	-1.7	-1.1	-1.1	3.7	-1.5	-0.5	1.1	0.2	-1.3
Arm fat percentage (right)	0.5	2.0	8.4	1.4	0.0	1.0	-0.3	-0.1	-1.2	2.6	-0.3	0.8	2.3	1.1	2.1	0.9	-0.1	-0.2	2.9
Trunk fat-free mass	0.3	1.5	10.2	1.3	-1.2	-0.4	-0.5	-1.2	-0.1	-0.7	-0.3	-0.5	1.2	-3.2	1.6	-0.4	-0.5	-0.8	1.4
Hip circumference	0.5	2.2	6.8	1.8	-1.3	-0.6	-0.8	-0.2	-1.3	1.9	-2.0	-0.4	2.1	0.6	1.8	0.0	-1.4	-1.5	2.6
Time employed in main current job	0.6	0.6	3.7	-0.2	-0.5	-1.1	-0.6	0.0	0.6	-0.4	-1.9	-0.7	-0.4	-0.5	-1.0	0.9	-0.6	-1.1	-0.3
Alcohol intake versus 10 years previously	0.5	0.7	3.7	0.4	0.2	0.6	-0.7	-0.0	0.1	-0.0	0.8	-0.2	-1.9	1.0	-0.2	0.5	0.3	1.0	-1.8
Father’s age at death	1.0	1.3	5.2	-1.1	0.7	2.3	0.0	-1.0	-0.4	1.2	1.8	1.4	-1.0	1.0	0.9	0.6	0.6	1.5	-1.0
Worrier / anxious feelings	0.4	0.8	4.3	-2.1	-0.1	-0.3	-0.6	-1.4	-0.1	-1.5	-0.5	-0.5	-0.1	-1.4	-0.7	-0.0	-0.6	-0.7	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.1	0.8	0.2	-0.2	0.5	-0.2	0.5	0.5	0.1	-0.1	0.8	-0.1	0.5	-0.5	0.7	0.1	1.1
Falls in the last year	0.9	1.3	6.3	2.5	0.4	-0.7	-0.2	-0.6	1.0	0.7	-0.6	-0.2	2.3	0.1	0.1	-0.1	0.5	-0.2	2.4
Hair/balding pattern: Pattern 3	0.3	0.5	1.5	0.5	-0.8	-0.4	0.5	1.2	-0.2	-0.8	0.2	-0.7	1.1	-0.2	0.9	-0.1	-0.6	-0.5	1.1
Number of live births	1.9	2.6	7.4	1.4	-1.9	-2.7	-1.5	-0.7	1.0	-1.5	-2.6	-2.0	1.0	-1.6	-0.9	-1.2	-1.4	-2.1	0.4
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	12.1	-1.3	-1.1	-1.6	-1.5	-1.2	3.1	-3.5	-1.8	-1.8	0.1	-2.6	-0.4	-2.2	1.9	-0.2	-0.6
Pulse rate	1.4	2.3	12.3	-3.5	-0.1	1.6	-1.9	-2.0	-0.4	1.5	-0.2	0.3	0.0	3.3	0.3	1.0	0.1	0.5	0.2
Happiness	1.0	1.3	4.6	-1.3	-1.2	-1.4	-1.2	-1.1	0.8	-0.2	-1.1	-1.2	-0.6	-0.2	-2.1	-1.2	-0.2	-1.4	-0.8
Noisy workplace	0.4	0.5	3.7	-0.4	-0.7	-0.2	-1.2	-1.9	0.1	-0.8	0.1	-0.1	-0.6	-1.0	-0.2	-0.5	-0.2	-0.4	-0.5
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.2	-0.7	-0.8	-1.2	-0.1	1.0	0.2	-0.9	-1.2	-1.3	1.8	0.3	-0.5	0.1	-1.0	-1.3	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	3.8	0.9	-0.2	-0.1	-0.0	-0.2	0.5	-0.1	-0.8	0.0	1.9	-1.1	1.2	-0.1	0.3	-0.2	1.8
Mouth/teeth dental problems: Dentures	0.3	0.6	2.2	1.2	0.5	0.7	0.8	0.5	-1.5	1.0	0.6	0.6	0.4	-0.2	0.2	0.9	-0.9	0.1	0.6
Asthma	1.6	3.1	9.2	3.0	-1.2	-2.5	-1.0	-0.3	2.2	-1.4	-1.8	-2.7	-1.8	-0.2	-2.1	-1.1	0.6	-0.6	-2.1
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.9	0.1	1.3	1.0	1.2	0.4	-0.2	1.3	0.5	1.7	0.7	1.0	0.9	1.0	0.5	1.0	0.9
Medication: Cholesterol lowering	0.2	0.4	1.1	0.8	-0.7	-0.9	-0.3	0.9	0.5	-1.0	-0.3	-0.5	0.3	-0.2	-0.1	0.3	-0.3	-0.8	0.5
Depression (self-reported)	0.6	0.8	2.5	-0.3	-0.9	-0.4	0.0	-1.1	-1.4	-1.1	-0.4	-0.9	-0.5	-0.9	-0.9	-0.6	-1.6	-1.3	-0.1
Medication: Lansoprazole	1.4	1.5	4.3	0.0	1.5	1.1	0.6	0.2	0.1	1.6	1.8	0.9	-0.9	2.1	-0.5	1.1	1.2	1.8	-1.7
Prospective memory result	0.6	0.7	2.1	1.2	-0.3	-0.3	-0.2	-0.1	1.5	-0.9	-0.8	-0.2	1.3	-0.5	0.4	-1.3	0.6	-0.4	1.3
Lung cancer (father)	0.3	0.4	1.8	0.5	-0.6	-1.4	0.5	0.7	0.5	-0.0	-0.3	-0.5	-1.0	0.4	-0.5	-0.3	-0.4	-0.7	-0.5
Illnesses of mother	0.6	0.7	2.8	-0.0	1.0	1.7	0.3	-0.3	0.3	0.2	1.3	1.1	-0.2	-0.2	-0.1	0.8	1.2	1.4	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.4	14.2	-2.1	-1.8	-2.0	-2.0	-2.2	2.6	-3.8	-2.0	-2.4	-0.7	-2.5	-0.9	-2.6	1.3	-0.7	-1.5
Pulse wave Arterial Stiffness index	0.8	0.9	4.5	1.0	0.7	0.4	0.9	0.5	0.5	-0.0	-0.7	0.5	2.1	-0.1	1.0	-0.3	1.0	0.5	1.9
Impedance of arm (left)	0.5	2.3	13.8	0.7	0.3	-1.4	0.3	2.5	1.8	1.3	-1.7	-0.9	-1.1	3.7	-1.3	-0.3	0.9	0.3	-1.3
Arm fat mass (right)	0.4	1.7	7.6	1.6	-0.4	0.6	-0.5	-0.5	-1.4	2.0	-0.3	0.6	2.2	-0.1	2.1	0.7	-0.6	-0.6	2.8
Trunk predicted mass	0.3	1.5	10.6	1.2	-1.2	-0.4	-0.6	-1.4	-0.1	-0.7	-0.3	-0.5	1.1	-3.3	1.5	-0.4	-0.4	-0.8	1.4
Standing height	0.2	1.9	6.5	2.5	-1.0	-2.2	-0.3	0.5	2.2	-0.8	-1.3	-1.6	-1.1	-1.7	-0.6	-1.2	0.8	-0.3	-1.2
Length of working week for main job	0.4	0.4	3.1	-0.0	-0.9	0.5	0.5	0.1	-1.0	0.1	0.6	0.1	0.0	-0.1	1.8	-0.0	-0.9	-0.1	0.5
Exposure to tobacco smoke at home	0.4	0.5	4.5	2.1	-0.3	-0.2	0.9	0.8	-0.3	-0.1	0.3	-0.4	0.3	-0.5	0.2	-0.3	-0.5	-0.3	0.2
Breastfed as a baby	0.7	0.9	3.2	-1.0	1.0	0.3	-1.1	-1.2	1.5	0.3	-0.2	0.7	1.0	-0.7	0.0	-0.4	1.8	0.8	1.0
Tense / ‘highly strung’	1.9	3.2	14.7	-3.8	-0.7	-1.5	-1.8	-2.1	2.0	-1.5	-1.7	-1.3	-1.0	-0.1	-2.5	-1.9	1.1	-0.7	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	8.3	-2.9	-0.7	-1.1	-1.5	-2.5	0.7	-1.6	-0.2	-1.3	-1.2	-1.4	-2.2	-1.8	0.1	-0.8	-1.3
Hair/balding pattern: Pattern 4	0.8	1.9	8.2	2.9	2.2	0.8	1.1	1.3	0.9	0.4	0.8	1.4	1.1	-0.9	0.8	0.3	1.5	1.9	1.2
Birth weight of first child	0.3	0.5	2.4	0.1	0.6	1.5	1.2	0.2	-0.4	0.3	0.6	1.2	0.0	-0.5	1.0	0.4	0.3	0.6	0.4
Peak expiratory flow (PEF)	1.1	2.5	8.8	-2.0	-0.4	-1.3	-1.7	-1.5	3.0	-1.7	-2.0	-1.1	1.4	-1.9	-0.2	-0.8	2.0	-0.2	0.9
Pulse wave reflection index	0.5	0.6	2.2	0.9	-0.6	-1.3	0.9	0.9	0.1	-0.8	-0.5	-0.7	0.4	-0.8	-0.1	-1.5	-0.1	-0.6	0.3
Ever highly irritable/argumentative for 2 days	0.4	0.5	5.2	-2.3	-0.2	0.0	0.5	-0.5	-0.6	-0.1	0.5	-0.3	-0.4	0.0	-0.7	-0.2	-0.3	-0.3	-0.7
Loud music exposure frequency	0.6	0.6	2.8	-0.7	0.6	-0.2	-0.7	0.2	1.2	0.2	-0.8	0.5	-0.6	0.6	-1.2	-0.2	1.7	0.4	-0.8
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	4.6	-1.0	0.8	0.4	0.7	0.3	1.7	-0.4	0.8	-0.2	1.4	0.6	-0.1	-0.8	2.2	1.0	0.8
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	4.5	-0.7	-0.4	-1.0	-1.0	-0.8	1.4	-1.4	-1.6	-1.0	-1.2	-1.4	-2.1	-2.1	1.0	-1.0	-0.5
Blood clot in the leg (DVT)	4.0	5.1	13.8	3.7	-3.2	-3.6	-1.1	0.4	-0.6	-2.3	-1.7	-3.2	-0.2	-0.4	-0.5	-1.6	-3.4	-3.2	0.2
Medication: Paracetamol	0.6	1.0	3.4	0.0	0.6	0.9	1.6	1.6	-1.1	0.9	0.3	0.9	-0.1	0.6	1.5	1.9	-0.7	0.5	0.1
Headache pain in last month	0.3	0.5	2.0	1.2	-0.3	-0.1	-0.4	-0.9	0.6	0.3	-1.4	-0.2	0.9	-1.4	0.6	0.1	-0.0	-0.3	0.8
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.9	-1.0	0.3	0.4	0.8	-0.2	-0.4	0.5	0.1	0.0	0.4	0.2	0.7	-0.1	-0.1	0.4	0.3
Glaucoma (self-reported)	0.6	0.7	2.2	1.5	-0.9	-1.0	-0.3	-0.4	-0.4	0.1	-1.3	-0.8	-0.0	0.5	-0.3	0.9	-1.4	-1.1	0.1
Gout (self-reported)	1.7	2.4	6.7	0.0	1.2	2.2	1.5	1.0	-2.5	1.6	2.6	1.6	-1.3	0.6	1.7	1.1	-0.5	1.7	-0.9
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	3.6	1.8	-0.5	-1.9	0.1	0.4	1.3	-1.1	-1.3	-0.7	1.2	-1.4	-0.5	-0.2	-0.3	-1.0	1.3
Medication: Amlodipine	0.6	0.9	2.9	-0.7	0.1	0.9	-0.2	-0.6	-1.5	0.8	1.7	0.6	0.3	0.1	1.0	1.6	-1.4	0.0	0.2
Medication: Ventolin 100micrograms inhaler	2.0	2.6	7.1	0.9	-1.9	-1.5	-1.1	-0.1	-0.4	-1.9	-0.9	-1.6	-2.4	-0.9	-2.7	-1.2	-1.3	-1.9	-2.6
Birth weight	0.9	1.9	6.4	0.8	-0.9	-1.4	-1.8	-1.7	1.4	-1.1	-0.5	-1.6	-1.7	-0.2	-2.5	-1.9	0.8	-0.8	-1.3
Chronic bronchitis/emphysema (mother)	0.9	1.0	3.8	0.8	0.7	0.4	0.6	1.3	0.3	2.0	0.1	0.5	0.9	1.9	1.0	1.1	0.8	0.9	1.0
High blood pressure (siblings)	0.6	0.8	3.2	-1.4	0.8	0.8	0.6	0.4	-0.7	1.8	0.7	1.1	-0.9	1.1	0.4	0.7	0.4	0.8	-0.6
Forced vital capacity (FVC), Best measure	0.9	3.3	9.7	-2.5	-1.5	-1.3	-1.6	-1.7	1.8	-3.1	-1.9	-2.0	-1.4	-2.0	-0.9	-1.9	0.8	-0.4	-2.1
Body fat percentage	0.5	1.9	6.9	1.7	0.3	1.0	-0.2	0.3	-1.2	2.6	0.0	1.1	1.9	1.4	1.9	1.2	-0.1	0.0	2.4
Leg fat percentage (right)	0.3	1.3	5.1	0.2	0.0	0.9	-0.6	-0.2	-1.6	1.7	0.0	0.8	1.8	0.6	1.7	0.8	-0.6	-0.3	2.2
Arm fat-free mass (right)	0.3	1.4	10.4	1.6	-1.3	-0.4	-0.8	-1.4	-0.7	-0.8	0.2	-0.3	0.4	-3.2	1.1	-0.4	-0.9	-1.0	0.8
Exposure to tobacco smoke outside home	0.7	0.9	4.0	1.9	0.5	-0.4	0.3	0.8	0.3	0.0	-0.2	-0.2	2.0	-0.5	1.1	0.2	-0.2	-0.1	1.9
Comparative body size at age 10	0.8	2.3	12.6	1.5	1.6	1.4	1.9	0.2	-0.6	1.8	3.5	1.5	1.1	0.5	1.4	-0.0	1.2	1.7	0.9
Number of full brothers	0.2	0.2	0.9	-0.5	-0.0	-0.1	-0.6	-0.2	0.3	-0.3	-0.4	-0.4	-0.9	-0.2	-0.4	0.4	0.0	0.2	-0.9
Worry too long after embarrassment	1.7	2.8	8.9	-3.0	-0.8	-1.9	-1.3	-1.4	2.4	-1.7	-0.8	-2.1	0.5	-1.8	-1.7	-2.5	0.9	-1.0	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	4.3	-1.7	-0.1	-0.0	-1.6	-2.1	0.2	-0.5	0.3	-0.5	-1.2	0.2	-2.0	-0.9	0.7	0.0	-1.5
Wheeze or whistling in the chest in last year	0.5	0.8	7.3	2.7	-0.9	-0.5	0.6	-0.1	-0.1	-0.6	0.3	-1.3	-0.4	-0.0	0.2	-1.0	-0.9	-0.4	-0.4
Number of children fathered	3.3	3.8	9.6	0.5	3.0	2.6	2.4	1.2	0.9	2.4	1.3	2.0	0.8	0.7	1.6	1.9	2.7	3.1	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	2.4	-1.5	-0.4	-0.7	-0.9	-0.5	-0.3	0.6	-0.4	-0.9	-0.4	1.5	-0.3	-0.4	-1.1	-0.4	-0.3
Age at first live birth	0.3	0.5	2.3	0.2	-0.2	0.8	1.1	0.8	-1.2	0.2	0.3	0.4	0.3	0.6	1.5	-0.3	-0.7	-0.1	0.7
Pulse wave peak to peak time	0.8	0.9	4.8	-1.1	-0.7	-0.5	-0.9	-0.6	-0.4	0.0	0.8	-0.6	-2.2	-0.0	-1.0	0.2	-0.9	-0.4	-2.0
Health satisfaction	0.9	1.2	2.5	1.5	-0.9	-1.6	-0.4	-0.5	1.2	-0.4	-1.6	-1.1	1.5	-0.9	-0.6	-1.2	0.1	-1.3	1.2
Shortness of breath walking on level ground	1.7	2.0	9.8	1.0	-1.0	-1.1	0.1	-0.2	0.6	-0.4	-1.7	-1.2	2.9	-0.4	0.6	-1.4	-0.3	-1.7	3.1
Qualifications: College or University degree	0.7	2.3	5.5	-2.3	-1.6	-1.4	-2.1	-2.3	1.3	-0.4	-2.1	-1.4	1.3	-0.0	-0.7	-1.7	-0.4	-1.6	0.7
Eye problems/disorders: None of the above	1.1	1.3	4.2	-1.1	2.0	1.6	0.4	0.9	0.0	1.3	1.4	1.5	-0.1	0.2	-0.5	0.5	1.5	1.6	-0.1
Mouth/teeth dental problems: Loose teeth	0.7	0.8	2.3	0.5	-1.0	-1.0	-1.4	-1.5	-0.3	-0.9	-0.6	-1.2	-0.6	0.3	-0.4	-0.4	-1.4	-0.8	-0.6
Emphysema/chronic bronchitis	2.6	3.0	7.8	0.2	-1.8	-1.9	-1.5	-1.5	0.6	-1.6	-1.0	-2.4	-2.3	0.4	-2.8	-1.6	-1.2	-1.5	-2.6
Medication for pain relief, constipation, heartburn	1.0	1.7	5.6	-0.9	-1.1	-1.3	-1.1	-1.1	1.1	-1.5	-0.7	-1.8	-0.7	-1.2	-2.1	-2.4	0.1	-1.0	-1.0
Neck or shoulder pain in last month	0.5	0.6	1.8	-1.3	1.4	1.1	0.2	-0.8	0.8	0.2	-0.6	0.9	0.8	-0.1	0.1	0.8	0.6	0.9	0.8
Medication: Blood pressure	0.2	0.4	1.6	0.4	-0.1	-0.0	-0.6	0.7	0.1	-0.1	0.4	0.3	-1.3	0.4	-0.8	0.9	-0.3	-0.3	-1.0
Angina (self-reported)	0.2	0.2	0.9	-0.3	0.4	0.0	0.2	0.8	-0.1	-0.3	0.4	0.3	0.7	0.2	-0.0	0.7	-0.5	-0.4	0.9
Migraine (self-reported)	1.3	1.6	6.8	0.7	1.6	-0.1	0.7	1.0	2.3	0.3	-1.0	1.0	-0.1	-2.3	-1.5	-0.3	2.6	0.7	-0.3
Medication: Ibuprofen	0.9	1.1	3.7	0.6	0.7	0.5	1.1	0.7	-0.6	1.5	0.0	1.4	1.2	1.9	1.1	1.0	-0.3	0.2	1.4
Medication: Allopurinol	1.9	2.5	8.5	-1.8	1.4	2.8	0.2	-0.7	-1.2	1.3	2.1	2.0	0.5	0.2	2.9	1.0	0.7	2.2	0.5
Medication: Omeprazole	0.5	0.5	2.3	-0.2	-0.4	0.7	-0.0	0.1	-1.4	0.3	0.1	0.3	-0.5	0.7	1.5	1.3	-1.0	-0.1	-0.2
Medication: Seretide 50 evohaler	0.5	0.6	2.2	1.3	-1.2	-0.3	-0.5	-1.5	0.5	-0.4	-0.6	-0.8	0.2	1.0	0.7	-0.8	0.1	-0.3	-0.1
Mean time to correctly identify matches	1.0	1.8	6.2	-2.5	1.6	1.5	1.5	0.8	-1.6	0.9	1.7	1.8	0.2	-0.2	1.0	1.5	-0.5	1.3	-0.2
Heart disease (mother)	0.7	0.9	3.6	-1.2	0.6	0.7	-0.6	-0.1	-1.2	0.8	0.4	0.9	1.7	0.8	1.3	0.0	-0.3	0.1	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	5.9	2.4	-0.2	-0.4	0.2	1.1	-0.1	0.4	-0.2	-0.3	-1.1	0.6	-0.8	-0.7	-0.1	-0.2	-0.6
Whole body fat mass	0.4	1.7	6.7	2.1	-0.3	0.6	-0.5	-0.3	-1.2	2.0	-0.2	0.7	2.1	0.1	2.0	0.9	-0.5	-0.5	2.6
Leg fat mass (right)	0.3	1.3	5.8	1.2	-0.3	0.7	-0.7	-0.6	-1.3	1.5	0.0	0.7	2.0	-0.5	1.8	0.4	-0.6	-0.5	2.4
Arm predicted mass (right)	0.2	1.3	9.5	1.4	-1.1	-0.2	-0.6	-1.2	-0.7	-0.7	0.3	-0.1	0.5	-3.1	1.4	-0.2	-0.8	-0.8	0.9
Pulse rate, automated reading	2.2	7.2	29.6	-5.4	0.8	3.3	-1.2	-1.2	-2.4	3.9	0.8	2.3	-0.8	4.9	1.9	3.6	-1.0	1.1	-0.1
Alcohol intake frequency.	0.5	1.1	11.2	3.3	0.6	0.4	0.8	0.7	0.3	0.3	0.5	0.3	-0.7	0.4	-0.5	0.5	1.2	1.1	-0.9
Comparative height size at age 10	0.0	0.2	1.3	1.1	-0.2	-0.6	-0.1	0.1	0.6	0.2	0.2	-0.3	-0.5	-0.2	-0.1	-0.1	0.7	0.4	-0.5
Number of full sisters	1.2	1.4	4.4	0.8	0.1	-0.2	-1.9	-1.7	1.8	-1.0	-0.9	-0.2	1.4	-2.1	-0.6	-0.1	0.9	-0.5	1.5
Suffer from ‘nerves’	0.5	0.8	4.0	-1.1	-0.4	0.2	0.9	-0.4	-0.6	-1.0	-0.6	-0.4	-1.7	-0.2	-1.0	-0.1	-0.5	-0.3	-2.0
Overall health rating	1.5	3.1	7.5	2.4	-1.8	-2.6	-1.3	-0.6	0.7	-1.7	-2.7	-1.9	1.1	-1.6	-0.6	-1.7	-1.3	-2.5	1.5
Chest pain or discomfort	2.6	3.8	9.1	1.2	-2.0	-2.5	-2.3	-1.1	1.6	-3.0	-2.1	-2.5	-0.7	-1.6	-2.3	-2.2	-0.7	-2.2	-0.5
Had major operations	1.3	1.5	4.8	-1.0	1.4	1.6	0.4	-0.3	-0.6	1.8	0.4	1.2	2.0	-0.1	1.6	0.3	0.7	1.1	2.2
Age at last live birth	0.5	0.7	2.9	-0.2	-0.8	0.2	0.8	0.9	-1.7	-0.6	-0.4	-0.3	0.6	-0.0	0.9	-0.9	-1.7	-0.8	0.5
Family relationship satisfaction	0.7	0.9	2.7	-1.6	-1.0	-0.5	-1.6	-1.4	0.2	0.2	-0.7	-1.0	-0.9	0.3	-1.0	-1.0	-0.2	-0.9	-0.6
Leg pain on walking	0.2	0.3	1.3	0.3	-0.1	0.1	1.1	0.0	-0.9	-0.2	1.1	0.1	0.0	-0.7	0.7	-0.0	-0.4	-0.1	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.8	0.6	0.5	0.4	1.7	1.1	-0.6	0.3	1.1	0.6	-0.2	0.6	0.5	-0.3	-0.1	0.6	-0.1
Commuting to job workplace: Car/motor vehicle	2.7	3.1	6.5	1.3	-1.8	-2.3	-0.5	0.7	2.6	-2.4	-2.2	-1.8	1.4	-1.9	-1.3	-2.5	0.9	-1.6	1.0
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.6	-0.6	0.7	0.7	0.2	1.3	0.7	0.0	0.1	0.6	-0.0	1.1	-0.2	1.2	0.8	0.4	0.2
Medication: Aspirin	0.4	0.6	3.2	0.7	0.2	-0.1	-0.9	-0.2	1.2	0.2	0.3	-0.3	-0.5	1.8	-0.6	0.2	1.2	0.7	-0.8
Supplements: Vitamin C	0.5	0.6	2.4	-0.9	-0.4	0.1	-1.4	-1.6	-0.2	-0.5	-1.2	-0.6	-0.7	0.0	-0.7	0.4	-0.6	-0.1	-1.1
Knee pain experienced in last month	0.6	0.9	2.3	0.8	0.2	0.6	1.1	0.2	-1.4	1.0	0.6	0.5	0.7	1.5	1.4	1.5	-1.3	0.2	0.8
Hypertension (Self-reported)	0.5	1.3	3.4	-0.7	1.3	1.2	-0.1	0.5	-1.4	1.5	1.8	1.8	0.0	1.7	0.5	1.5	-0.1	0.8	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	5.5	-0.9	1.7	1.9	0.9	-0.1	-1.1	1.3	1.2	1.6	-0.0	0.3	1.2	2.4	0.6	1.6	-0.0
Illnesses of father: Heart disease	0.1	0.2	1.0	0.2	0.4	0.0	0.8	1.0	0.4	0.4	-0.1	0.1	0.5	0.1	0.1	-0.2	0.8	0.3	0.3
Illnesses of siblings: Diabetes	1.8	2.2	6.9	-0.7	-2.6	-1.9	-2.1	-1.8	-0.5	-1.5	-0.4	-2.3	-0.3	0.1	-0.3	-1.1	-1.8	-2.0	-0.2
Smoking status: Previous	0.4	0.6	1.5	-0.1	1.0	0.3	-0.8	-0.9	1.1	0.3	0.0	0.9	0.8	-0.9	0.2	0.5	1.2	0.6	0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	3.0	0.2	-1.7	-0.7	-0.5	-0.7	0.2	-0.8	-0.9	-1.6	-0.1	0.4	1.1	-1.2	-0.8	-0.8	-0.0
Whole body fat-free mass	0.3	1.5	8.9	2.0	-1.3	-0.4	-0.5	-1.1	-0.4	-0.4	-0.1	-0.4	1.1	-3.0	1.5	-0.4	-0.7	-1.0	1.4
Leg fat-free mass (right)	0.3	1.5	7.2	2.7	-1.4	-0.4	-0.2	-0.7	-0.6	0.3	-0.0	-0.4	1.3	-2.0	1.6	-0.4	-0.9	-1.1	1.5
Arm fat percentage (left)	0.5	2.2	8.8	1.7	-0.1	0.8	-0.2	0.2	-1.3	2.6	-0.5	0.8	2.4	1.1	2.2	1.0	-0.4	-0.4	3.0
Average weekly red wine intake	0.2	0.3	0.9	-0.2	0.6	0.1	0.3	0.7	1.0	0.2	-0.0	0.7	0.6	-0.4	-0.4	0.4	0.7	-0.0	0.6
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.4	1.2	0.6	0.1	0.9	0.5	0.4	-0.1	0.7	-0.2	0.6	-0.1	-0.6	-1.1	0.9	0.2	0.4
Mood swings	2.1	3.8	8.6	-2.1	-2.0	-2.1	-2.9	-2.6	1.0	-2.5	-2.0	-1.8	-0.2	-2.4	-2.0	-2.0	-0.5	-2.0	-0.4
Loneliness, isolation	0.1	0.1	0.4	-0.6	0.2	-0.1	-0.1	-0.1	0.5	-0.1	0.4	0.2	-0.4	-0.3	-0.6	-0.0	0.2	0.1	-0.3
Long-standing illness, disability or infirmity	0.5	0.8	6.9	2.6	-0.2	-0.6	0.1	1.0	0.2	0.6	-0.7	-0.3	0.2	1.0	0.8	0.6	-0.8	-0.3	0.4
Ever had bowel cancer screening	0.8	0.9	3.4	1.8	1.0	0.6	0.8	0.8	1.4	-0.5	0.1	0.9	0.2	-1.3	-0.0	-0.1	1.7	0.9	0.4
Diabetes diagnosed by doctor	0.5	0.8	3.1	1.7	-0.9	-0.9	-0.8	0.2	-0.4	-1.8	0.3	-0.9	0.5	-0.9	-0.1	0.2	-1.4	-1.0	0.7
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	4.3	-1.6	-2.1	-0.8	-0.2	-1.2	-0.0	-0.4	-1.7	-1.8	1.4	0.3	1.3	-1.3	-1.0	-1.4	1.3
Friendships satisfaction	0.7	0.8	2.7	-0.6	-0.8	-1.4	-1.1	-0.6	1.2	-0.7	-0.9	-1.1	-0.7	0.3	-1.6	-0.5	-0.0	-0.9	-0.8
Qualifications: nursing, teaching	0.4	0.7	2.3	-1.3	-0.2	-0.8	-0.6	-0.4	-0.0	1.1	-0.3	-0.5	1.4	1.5	0.1	-0.3	-0.4	-0.7	1.1
Commuting to job workplace: Walk	0.7	0.7	2.8	-0.7	1.7	0.8	0.2	0.0	1.0	1.0	0.1	1.0	0.4	1.1	-0.2	0.2	1.4	1.1	0.5
Eye problems/disorders: Cataract	0.6	0.7	2.6	-0.5	-1.4	-1.6	0.1	-0.3	-0.2	-0.3	-0.7	-0.9	0.5	0.6	1.0	-0.7	-1.1	-1.2	0.7
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	10.9	-3.3	0.6	0.1	-0.5	-1.6	-0.2	-0.3	0.4	-0.1	2.1	0.1	-0.2	-0.4	-0.1	-0.1	1.8
Medication for cholesterol	0.5	0.7	2.5	0.1	-1.5	-0.6	-0.5	-0.8	-0.8	-0.2	-0.4	-0.9	-0.9	-1.1	-0.3	0.1	-1.6	-1.2	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.8	6.8	2.6	-0.9	-1.0	0.8	1.4	0.7	-1.2	-1.5	-0.4	1.7	-1.9	1.0	-1.0	0.3	-1.1	2.0
Back pain experienced in last month	0.2	0.3	1.6	-0.5	-0.1	0.6	-0.2	0.3	-0.7	0.1	-0.4	0.5	-0.0	-0.6	0.9	1.3	-0.7	-0.3	0.3
Mineral and other dietary supplements	0.7	1.0	3.5	-0.4	0.4	0.9	-0.7	-1.0	-1.2	0.8	0.7	0.4	1.4	-0.4	1.9	1.2	-0.7	0.2	1.7
Breast cancer (self-reported)	0.4	0.5	2.3	0.3	0.1	-0.5	-0.2	1.0	0.1	-1.0	0.6	0.7	-0.7	-0.8	-1.5	0.4	-0.3	-0.4	-0.6
Asthma (self-reported)	1.7	3.4	9.5	3.1	-1.3	-2.5	-1.0	-0.5	2.4	-1.4	-1.8	-2.7	-1.9	-0.1	-2.2	-1.4	0.8	-0.6	-2.2
Osteoporosis (self-reported)	1.1	1.3	5.3	2.2	0.3	-0.6	-0.4	0.4	2.3	-0.3	-1.3	-0.1	0.1	-1.1	-1.7	-1.2	1.7	-0.1	-0.4
Osteoarthritis (self-reported)	1.5	1.9	6.9	0.7	1.5	1.1	2.6	1.9	-1.1	1.5	1.6	1.4	1.1	0.8	1.3	1.5	-0.2	1.1	1.1
Medication: Aspirin	0.4	0.5	2.4	0.7	0.3	-0.0	-1.0	-0.3	1.0	0.3	0.5	-0.2	-0.4	1.6	-0.4	0.3	1.0	0.9	-0.7
Medication: Gliclazide	0.3	0.4	1.8	0.9	0.1	0.0	0.6	1.4	0.7	-0.9	-0.2	0.2	0.3	-0.7	0.1	0.4	0.1	-0.1	0.6
Illnesses of father: None of the above (group 1)	0.9	1.1	4.2	-0.1	-1.1	-0.9	-0.3	0.1	-0.5	-1.2	0.4	-1.1	-2.0	-0.3	-1.3	-1.0	-1.1	-1.0	-1.7
Smoking status: Current	1.3	2.1	8.0	2.8	-1.2	-0.2	1.4	1.4	-1.8	0.3	0.4	-0.6	-2.4	1.7	0.1	0.4	-1.8	-0.6	-2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	4.4	-2.1	-0.3	-0.5	-0.7	-1.2	1.1	-1.7	-1.0	-0.5	0.4	-1.8	-0.4	-0.0	0.3	-0.2	-0.2
Whole body water mass	0.3	1.4	8.5	2.0	-1.3	-0.4	-0.5	-1.1	-0.3	-0.3	-0.2	-0.4	1.1	-2.9	1.5	-0.4	-0.6	-0.9	1.4
Leg predicted mass (right)	0.3	1.4	7.0	2.6	-1.4	-0.3	-0.1	-0.7	-0.6	0.3	-0.0	-0.3	1.3	-2.0	1.7	-0.3	-0.8	-1.0	1.5
Arm fat mass (left)	0.4	1.7	8.2	1.8	-0.4	0.5	-0.6	-0.3	-1.1	1.8	-0.4	0.6	2.3	-0.1	2.0	0.6	-0.4	-0.6	2.9
Number of self-reported non-cancer illnesses	0.2	0.4	2.6	1.6	0.3	-0.6	0.4	0.8	0.5	0.1	-0.8	-0.0	-0.3	0.7	-0.4	0.4	0.5	0.3	-0.4
Average weekly champagne plus white wine intake	1.1	1.5	4.4	-2.1	-1.1	-0.3	-1.3	-1.6	-0.8	0.1	-1.7	-1.0	1.4	0.9	0.6	0.6	-1.6	-1.3	1.4
Miserableness	2.0	3.5	8.0	-2.8	-1.9	-1.9	-2.8	-2.8	1.6	-2.0	-1.8	-2.0	0.4	-1.2	-1.6	-2.2	0.2	-1.8	0.3
Guilty feelings	0.6	0.9	3.2	-1.8	0.2	-1.0	-0.4	-0.5	1.3	-1.2	-0.3	-1.2	0.9	-0.7	-1.6	-0.8	0.6	-0.7	0.6
Wears glasses or contact lenses	1.8	2.0	4.7	-2.1	1.5	1.9	1.5	1.2	-0.7	1.5	1.0	1.5	0.1	1.9	1.3	2.2	0.2	1.5	0.1
Ever taken oral contraceptive pill	1.2	1.4	4.9	-0.7	0.0	-0.8	-0.7	-0.9	2.2	0.3	-1.8	-0.6	2.1	-0.1	0.4	0.6	1.7	-0.1	1.8
Hearing aid user	0.8	1.0	4.8	2.2	0.9	0.3	1.0	0.8	0.8	1.1	0.6	0.8	0.4	1.3	0.2	0.8	1.2	1.1	-0.0
Mother’s age at death	2.3	2.9	8.6	-2.0	-1.1	-1.3	-1.8	-1.9	0.8	-1.6	-2.4	-0.6	2.8	-1.8	0.7	-0.3	-0.6	-1.7	2.9
Financial situation satisfaction	1.8	2.2	6.7	-0.5	-1.6	-1.7	-2.6	-2.2	0.1	-1.3	-1.1	-1.7	-0.0	-1.4	-2.0	-0.5	-1.4	-1.9	-0.1
Tinnitus: Yes, now most or all of the time	1.1	1.3	6.4	1.4	-0.3	0.5	1.2	0.9	-2.5	0.7	0.7	0.7	0.7	0.6	1.3	1.1	-1.9	-0.5	0.5
Commuting to job workplace: Public transport	1.4	1.7	4.3	-1.3	1.1	1.8	-0.2	-1.3	-2.1	1.4	0.2	1.4	0.6	0.5	2.0	1.6	-1.2	0.7	1.3
Eye problems/disorders: Glaucoma	0.7	0.8	2.5	0.9	-1.4	-1.0	-0.9	-0.6	-0.3	-0.1	-1.6	-0.5	0.4	0.1	0.1	0.8	-1.4	-1.4	0.4
Medication: Blood pressure	1.0	1.8	3.5	-1.1	1.7	1.6	0.1	0.1	-0.5	1.2	1.3	1.5	1.8	1.9	1.6	1.3	1.0	1.4	1.7
Pain type(s) experienced in last month: Hip pain	1.8	2.3	5.5	-1.5	0.6	1.2	2.0	1.8	-1.9	1.5	1.1	1.1	0.9	1.7	2.1	2.3	-1.4	0.5	1.2
Supplements: Fish oil (including cod liver oil)	0.4	0.6	2.4	0.8	0.2	-0.6	0.4	0.8	1.6	-0.4	-0.1	0.0	-0.9	0.5	-0.9	-0.8	1.0	0.4	-1.0
High cholesterol (Self-reported)	0.6	1.0	9.7	3.1	-0.9	-0.9	-0.8	0.2	0.5	-1.3	-0.2	-0.7	-0.4	-0.6	-0.5	-0.5	-0.4	-0.6	-0.2
Medication: Bendroflumethiazide	0.1	0.2	0.9	-0.3	-0.4	-0.1	-0.8	0.4	-0.3	-0.2	-0.4	-0.1	0.1	1.0	0.2	0.6	-0.9	-0.5	0.1
Medication: Paracetamol	0.9	1.4	4.5	0.2	0.9	0.8	1.8	1.7	-0.8	1.3	-0.0	1.3	0.5	1.4	1.9	2.1	-0.3	0.7	0.6
Medication: Lisinopril	0.5	0.7	2.8	-0.9	-0.1	-0.1	-1.7	-1.0	-0.2	0.3	0.7	-0.9	-1.2	1.4	-0.9	0.1	-0.0	0.0	-1.0
Medication: Atorvastatin	0.2	0.3	1.6	-0.3	0.4	0.3	-0.3	0.1	0.3	0.8	0.1	0.6	-0.0	1.3	0.2	0.6	0.7	0.6	0.1
Illnesses of father: High blood pressure	1.1	1.3	4.9	1.4	1.2	0.7	0.1	-0.6	0.8	0.6	0.7	1.0	2.2	-0.8	1.3	0.4	1.2	0.8	2.2
Alcohol drinker status: Never	1.6	1.9	4.5	2.1	1.6	1.1	1.4	1.8	-1.1	1.2	1.8	1.4	1.1	0.7	1.4	1.5	0.5	1.3	1.0
Ever smoked	0.3	0.5	1.6	1.3	-0.8	-0.8	-0.9	-0.8	0.7	-0.9	-0.6	-0.6	-0.4	-0.5	-0.7	-0.8	0.1	-0.8	-0.3
Basal metabolic rate	0.2	1.4	6.2	2.1	-1.2	-0.3	-0.5	-1.0	-0.5	-0.0	-0.2	-0.4	1.3	-2.5	1.6	-0.3	-0.6	-0.9	1.6
Leg fat percentage (left)	0.5	1.7	4.4	0.4	0.3	1.5	-0.1	0.1	-2.1	2.0	0.8	1.3	1.6	0.8	1.9	1.4	-0.8	0.1	2.1
Arm fat-free mass (left)	0.3	1.4	9.1	1.4	-1.0	-0.2	-1.0	-1.7	-0.5	-0.5	0.2	-0.2	1.0	-3.0	1.2	-0.4	-0.4	-0.7	1.4
Number of operations (self-reported)	0.6	0.9	4.0	-0.8	0.7	0.2	-0.6	-0.4	1.0	-0.1	0.4	0.5	1.9	-0.7	1.2	-0.7	1.0	0.4	2.0
Average weekly beer plus cider intake	1.0	1.5	6.1	0.9	-0.8	-1.0	-0.7	-0.7	0.7	-0.3	0.5	-1.3	-2.3	0.9	-1.7	-1.6	0.7	0.1	-2.5
Irritability	0.9	1.6	10.4	-3.2	-1.6	-0.8	-1.6	-1.6	-0.0	-0.2	-1.4	-1.0	-0.0	0.6	-0.4	-0.2	-0.8	-1.6	0.3
Risk taking	1.4	2.0	5.9	-0.4	-2.1	-2.4	-1.5	-0.5	0.6	-1.1	-1.4	-2.4	0.2	0.9	-0.9	-1.5	-1.5	-1.8	-0.1
Ever had prostate specific antigen (PSA) test	0.9	1.0	2.5	-1.3	1.6	1.2	0.8	-0.3	0.1	1.1	1.2	0.9	-0.9	0.3	-0.1	0.5	1.4	1.6	-0.9
Fractured/broken bones in last 5 years	1.3	1.6	4.6	2.1	1.3	0.3	1.2	0.5	1.1	0.9	0.5	0.2	2.0	0.8	0.7	-1.2	2.1	1.2	1.6
Age started oral contraceptive pill	0.7	0.8	3.3	-0.8	1.8	0.6	-0.5	-0.6	1.2	-0.1	0.8	0.7	0.4	-0.6	-0.5	0.5	1.6	1.4	0.4
Diastolic blood pressure, automated reading	0.9	2.7	12.8	-0.8	-1.2	-0.2	0.4	1.4	-3.6	1.0	0.8	-0.0	-1.7	2.5	-0.2	0.8	-3.3	-1.6	-1.1
Ever depressed for a whole week	1.2	1.5	4.8	-2.2	1.0	1.1	-0.6	-1.4	0.9	0.1	-0.1	0.7	-1.2	-0.9	-1.7	-0.8	2.1	0.9	-1.4
Unable to work because of sickness or disability	1.6	2.1	7.5	2.3	-1.9	-1.6	-0.5	0.2	-1.2	-1.3	-0.6	-1.9	-0.2	-0.5	-1.2	-0.8	-2.7	-2.1	-0.1
Commuting to job workplace: Cycle	0.2	0.2	0.5	-0.6	0.3	0.2	-0.7	-0.4	0.4	0.3	0.1	0.1	0.2	-0.2	0.7	-0.6	0.5	0.7	0.1
Myopia	0.6	0.9	1.7	-1.3	-0.9	-0.3	-1.3	-0.9	-0.4	-1.1	-0.4	-1.1	-1.1	0.3	-1.3	-0.1	-0.9	-1.0	-1.3
Vascular/heart problems diagnosed by doctor	0.3	0.7	2.2	0.2	-1.1	-0.8	0.0	-0.2	0.6	-1.1	-1.2	-1.5	-0.3	-1.5	0.0	-0.8	-0.5	-0.6	-0.3
Cholesterol lowering medication	0.5	0.7	6.5	2.5	-0.1	-0.4	-1.1	-0.4	0.3	-0.7	0.1	-0.2	0.8	-0.2	0.7	-0.4	-0.4	-0.0	1.1
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	4.1	-0.1	-0.1	1.0	0.5	0.4	-1.2	0.8	0.6	0.8	-0.2	0.9	2.0	1.3	-0.4	0.4	0.1
Pain experienced in last month	0.8	1.4	4.1	-0.1	-0.4	-1.7	-1.4	-0.7	2.0	-1.4	-0.3	-1.2	-0.3	-0.4	-2.0	-1.7	1.3	-0.4	-0.7
Supplements: Calcium	0.7	0.7	2.5	0.0	-1.1	-0.8	0.9	1.3	-0.3	-0.2	-1.6	-0.4	-0.6	-0.1	-1.1	-0.3	-0.9	-1.4	-0.5
Basal cell carcinoma (self-reported)	1.1	1.3	4.1	1.1	0.4	0.6	1.6	2.0	-1.1	0.8	1.2	0.6	-1.7	0.8	-0.3	0.7	-0.5	0.9	-1.9
Heart attack/myocardial infarction (self-reported)	1.2	1.6	5.5	1.7	0.5	-0.1	2.1	2.4	0.3	0.1	1.4	0.1	-1.8	1.4	-0.4	0.2	0.5	0.9	-2.0
Deep venous thrombosis (DVT) (self-reported)	3.3	4.2	12.7	3.6	-2.8	-3.3	-0.9	0.6	-0.8	-1.8	-1.5	-2.8	-0.0	-0.2	-0.1	-1.2	-3.3	-2.9	0.4
Heart disease (siblings)	0.3	0.4	1.4	-0.8	-0.1	-0.3	-0.5	-0.6	0.4	0.1	-0.8	-0.1	-1.0	0.3	-0.9	0.6	0.3	-0.0	-1.2
Alcohol drinker status: Previous	0.4	0.5	2.6	-0.5	-0.1	0.4	0.1	-0.7	1.0	-0.4	0.1	-0.3	-1.2	0.8	-0.5	0.3	0.6	0.6	-1.6
Pack years of smoking	0.5	0.7	2.8	0.4	-1.2	-0.2	0.8	0.5	-1.6	-0.9	0.4	-0.4	-0.4	-0.7	0.7	0.2	-1.7	-0.9	-0.5
Impedance of whole body	0.4	2.2	10.3	0.3	0.3	-1.4	-0.2	1.9	1.9	0.3	-1.3	-1.1	-1.9	3.2	-1.9	-0.6	1.1	0.5	-2.1
Leg fat mass (left)	0.4	1.4	5.7	1.4	-0.1	0.9	-0.5	-0.4	-1.5	1.6	0.4	0.9	1.9	-0.4	1.8	0.6	-0.6	-0.3	2.4
Arm predicted mass (left)	0.3	1.3	9.9	1.3	-0.9	-0.1	-1.0	-1.7	-0.5	-0.6	0.2	-0.2	0.8	-3.1	1.1	-0.4	-0.3	-0.7	1.1