TWAS hub - INSL5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Papillary Cell Carcinoma	0.112	0.052	0.0012	-0.005	0.006	-0.004	NA	-0.003	0.78000	0.13000	0.7000	NA	0.5700
2	TCGA	Uterine Corpus Endometrial Carcinoma	0.187	0.082	0.0040	0.120	0.115	0.098	NA	0.079	0.00032	0.00043	0.0011	NA	0.0033

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Seen doctor (GP) for nerves, anxiety, tension or depression	14.6	22.3	22.8	4.8	4.7
Seen a psychiatrist for nerves, anxiety, tension or depression	11.6	15.0	15.1	3.9	3.9
Tense / ‘highly strung’	8.8	14.6	16.6	3.5	4.1
Serious illness, injury or assault to yourself	7.1	8.6	12.4	2.2	3.5
Medication: Gliclazide	6.7	7.5	8.9	3.0	2.5
Pulse rate, automated reading	6.6	21.2	30.7	-5.5	-3.4
Severe depression (siblings)	5.7	6.4	8.4	2.1	2.9
Irritable Bowel Disease (IBD)	5.6	13.2	14.9	3.9	3.4
Had major operations	5.3	6.3	8.0	2.1	2.8
Qualifications: CSEs or equivalent	5.2	6.9	9.4	3.1	2.1
Other serious medical condition/disability diagnosed by doctor	4.8	6.3	7.6	2.8	2.2
Crohns Disease (2017)	4.4	9.7	10.1	3.0	3.2
Frequency of tenseness / restlessness in last 2 weeks	4.0	6.2	7.3	2.7	2.3
Worry (Nagel 2018)	3.9	8.2	9.8	2.6	3.1
Stomach or abdominal pain in last month	3.9	4.8	6.2	1.8	2.5
Unable to work because of sickness or disability	3.9	5.0	6.5	2.5	1.9
LDL Cholesterol	3.8	6.0	9.1	-1.7	-3.0
Shortness of breath walking on level ground	3.8	4.5	7.8	1.1	2.8
Ulcerative Colitis (UC)	3.7	7.0	8.5	2.9	2.3
Ever smoked	3.5	6.1	6.8	-2.6	-2.3
Pulse rate	3.4	5.8	6.9	-2.6	-2.2
Smoking status: Previous	3.2	4.8	6.7	-2.6	-1.7
Past tobacco smoking	3.1	5.7	7.2	2.7	2.0
Neck or shoulder pain in last month	3.1	4.4	5.7	1.7	2.4
Nervous feelings	3.0	5.6	6.1	2.3	2.5
Falls in the last year	3.0	4.0	7.8	2.8	0.5
Ever depressed for a whole week	3.0	3.7	3.8	1.9	2.0
Systolic blood pressure, automated reading	2.8	8.1	11.6	2.2	3.4
Father’s age at death	2.8	3.7	5.3	-1.4	-2.3
Age started oral contraceptive pill	2.8	3.5	5.1	-2.2	-1.4
Systolic Blood Pressure	2.7	13.4	20.5	2.5	4.5
Frequency of depressed mood in last 2 weeks	2.7	3.8	4.2	2.0	1.8
Eye problems/disorders: None of the above	2.7	3.1	5.0	2.2	1.1
Pain type(s) experienced in last month: Hip pain	2.7	3.4	5.3	1.2	2.3
Illnesses of siblings	2.6	3.6	6.2	-1.0	-2.5
Number of live births	2.5	3.5	4.5	2.1	1.6
Alcohol intake frequency.	2.5	5.7	6.7	2.6	2.2
Long-standing illness, disability or infirmity	2.5	3.8	5.5	2.4	1.5
Supplements: Calcium	2.5	2.7	3.4	1.8	1.4
Ever had bowel cancer screening	2.4	2.8	2.9	1.7	1.7
Alcohol usually taken with meals	2.3	3.6	6.4	-2.5	-0.9
Pulse wave reflection index	2.3	2.8	5.0	0.8	2.2
Chronotype (morning person)	2.2	5.2	6.0	-2.1	-2.5
High blood pressure	2.2	6.2	12.2	0.5	3.5
Medication: Paracetamol	2.2	3.7	6.4	-2.5	-1.0
Qualifications: A levels/AS levels or equivalent	2.1	4.7	6.5	-2.5	-1.7
Mouth/teeth dental problems: Loose teeth	2.1	2.5	3.6	1.2	1.9
Number of operations (self-reported)	2.1	3.2	3.2	1.8	1.8
Ovarian Cancer	2.0	2.6	4.8	0.7	2.2
Frequency of tiredness / lethargy in last 2 weeks	2.0	3.2	4.3	2.1	1.4
High blood pressure (siblings)	2.0	2.9	5.1	0.8	2.3
Illness, injury, bereavement, stress in last 2 years	2.0	2.5	4.5	-0.7	-2.1
Ulcerative Colitis	1.9	2.8	4.6	2.1	1.0
Overall health rating	1.9	4.1	6.8	2.6	1.2
Guilty feelings	1.9	2.9	3.4	1.5	1.8
Mother’s age at death	1.9	2.3	2.8	-1.7	-1.4
Major Depression (MDD)	1.8	2.2	3.7	0.8	1.9
Prostate Cancer	1.8	2.5	4.9	-0.2	-2.2
Crohns Disease (2012)	1.8	2.8	4.3	2.1	1.2
Vascular/heart problems diagnosed by doctor	1.8	4.9	9.4	-0.6	-3.1
Basal cell carcinoma (self-reported)	1.8	2.1	2.2	1.4	1.5
Verbal and Numeric Reasoning (VNR)	1.7	4.0	5.1	-1.7	-2.3
Triglycerides	1.7	2.7	3.3	-1.5	-1.8
Alcohol drinker status: Never	1.7	2.1	2.7	1.2	1.6
Vitamin and mineral supplements	1.6	2.1	2.4	-1.5	-1.4
Mouth/teeth dental problems: Dentures	1.6	2.6	4.2	2.1	1.0
Birth weight of first child	1.6	3.0	5.7	-0.5	-2.4
Health satisfaction	1.6	2.1	3.1	1.1	1.8
Hypertension (Self-reported)	1.6	4.5	8.8	0.4	3.0
Eye problems/disorders: Cataract	1.6	1.8	3.7	-1.9	0.0
Medication: Bendroflumethiazide	1.6	2.4	4.0	0.9	2.0
Alzheimer’s Disease (including proxy)	1.5	2.2	3.2	1.0	1.8
Cardiovascular Disease	1.4	4.6	8.1	1.1	2.8
Diabetes (mother)	1.4	1.7	3.3	1.8	0.4
Multivitamins +/- minerals	1.4	1.8	2.7	1.6	1.0
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.2	6.0	-0.7	-2.5
Worrier / anxious feelings	1.4	2.6	4.0	1.1	2.0
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	3.1	0.7	1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	1.8	-1.2	-1.4
Financial situation satisfaction	1.4	1.8	2.0	1.2	1.4
Fractured/broken bones in last 5 years	1.4	1.8	3.3	0.5	1.8
Alcohol drinker status: Previous	1.4	1.6	2.6	0.7	1.6
Body Mass Index (BMI) (2010)	1.3	1.7	1.9	-1.3	-1.4
Neuroticism (2016)	1.3	1.8	3.3	0.6	1.8
Mouth/teeth dental problems	1.3	2.0	2.0	-1.4	-1.4
Fluid intelligence score	1.3	2.8	3.8	-1.3	-1.9
Family relationship satisfaction	1.3	1.6	2.4	-0.9	-1.6
Heel T-Score	1.2	9.6	18.7	-0.7	-4.3
Prospective memory result	1.2	1.4	2.9	1.7	0.1
Age at first live birth	1.2	2.2	4.3	-2.1	-0.4
Alzheimer’s Disease (in mother)	1.1	1.3	2.0	0.8	1.4
Alzheimer’s Disease (in father)	1.1	1.1	2.2	0.4	1.5
Smoking Status	1.1	2.5	3.4	-1.8	-1.3
Hand grip strength (left)	1.1	2.9	4.3	1.2	2.1
Leg fat-free mass (left)	1.1	5.6	10.2	3.2	1.0
Leg predicted mass (left)	1.1	5.8	10.4	3.2	1.1
Exposure to tobacco smoke at home	1.1	1.3	2.6	1.6	0.1
Wheeze or whistling in the chest in last year	1.1	2.0	3.0	1.0	1.7
Suffer from ‘nerves’	1.1	1.8	2.7	1.0	1.6
Leg fat-free mass (right)	1.1	6.0	10.8	3.3	1.1
Leg predicted mass (right)	1.1	5.9	10.4	3.2	1.1
Number of self-reported non-cancer illnesses	1.1	1.9	2.7	1.1	1.6
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	2.1	0.8	1.4
Depression (Nagel 2018)	1.0	1.5	2.0	1.4	0.9
Relative age voice broke	1.0	1.5	2.6	-1.6	-0.7
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.2	1.5	0.4
Medication: Atenolol	1.0	1.3	2.3	0.5	1.5
Pain all over the body in last month	1.0	1.1	1.3	1.1	0.9
Medication: Lansoprazole	1.0	1.1	1.2	-1.1	-1.0
Lung cancer (father)	1.0	1.2	1.2	1.1	1.1
Ever highly irritable/argumentative for 2 days	1.0	1.2	2.1	0.5	1.4
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	3.0	-1.7	-0.5
Osteoporosis (self-reported)	1.0	1.2	2.2	0.5	1.5
Supplements: Fish oil (including cod liver oil)	1.0	1.3	2.1	-1.4	-0.7
Medication: Lisinopril	1.0	1.3	1.3	-1.1	-1.1
Angina	0.9	1.2	2.0	1.4	0.7
Medication: Metformin	0.9	1.2	1.9	1.4	0.7
Taking other prescription medications	0.9	1.4	2.1	1.5	0.8
Impedance of leg (left)	0.9	4.2	8.2	-2.9	-0.4
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	1.6	0.8	1.3
Neuroticism score	0.9	1.9	1.9	1.4	1.4
Medication: Allopurinol	0.9	1.2	1.6	-1.3	-0.8
Whole body fat-free mass	0.9	5.2	8.6	2.9	1.3
Medication: Blood pressure	0.9	1.7	3.1	-0.5	1.8
Medication: Paracetamol	0.9	1.4	2.0	-1.4	-0.8
Basal metabolic rate	0.9	4.9	8.4	2.9	1.2
Intelligence (Savage-Jansen 2018)	0.8	2.4	3.6	-1.9	-1.1
Blood White Count	0.8	5.8	6.1	2.5	2.4
Number of treatments/medications taken	0.8	1.4	1.7	-1.0	-1.3
Impedance of leg (right)	0.8	4.1	8.0	-2.8	-0.3
Hand grip strength (right)	0.8	2.3	4.2	0.6	2.0
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	2.7	-0.9	-1.6
Trunk fat-free mass	0.8	4.3	6.7	2.6	1.4
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	1.6	0.5	1.3
Trunk predicted mass	0.8	4.6	6.9	2.6	1.5
Medication: Amlodipine	0.8	1.1	2.2	-1.5	-0.2
Migraine (self-reported)	0.8	1.0	1.9	-1.4	-0.1
Medication: Ibuprofen	0.8	0.9	1.2	-0.8	-1.1
Illnesses of father: Heart disease	0.8	1.1	2.0	-0.3	1.4
Whole body water mass	0.8	4.6	7.7	2.8	1.2
Cholesterol lowering medication	0.8	1.1	2.0	1.4	0.5
Heart disease (siblings)	0.8	1.0	1.9	1.4	0.3
Fasting Glucose	0.7	0.9	0.9	0.9	0.9
Lupus	0.7	1.0	1.6	-1.3	0.6
Townsend deprivation index at recruitment	0.7	1.0	1.9	0.3	1.4
Hip circumference	0.7	3.1	6.2	2.5	0.4
Noisy workplace	0.7	0.8	1.3	-0.6	1.1
Comparative body size at age 10	0.7	1.8	3.5	-0.4	-1.9
Number of full brothers	0.7	0.9	1.7	-1.3	0.1
Emphysema/chronic bronchitis	0.7	0.8	0.8	0.9	0.9
Medication for pain relief, constipation, heartburn	0.7	1.2	1.7	1.3	0.8
Breast cancer (self-reported)	0.7	0.8	1.2	-0.7	-1.1
Arm fat-free mass (left)	0.7	3.7	5.8	2.4	1.3
Arm predicted mass (left)	0.7	3.8	5.9	2.4	1.3
Reaction Time	0.6	1.2	1.7	1.3	0.8
Rheumatoid Arthritis	0.6	0.8	1.0	1.0	0.8
Hearing difficulty/problems: Yes	0.6	0.9	1.1	-0.8	1.1
Ever had hysterectomy (womb removed)	0.6	0.7	0.9	0.7	-0.9
Diabetes (father)	0.6	0.7	0.7	-0.9	-0.8
Hair/balding pattern: Pattern 2	0.6	0.7	1.5	-0.0	1.2
Diabetes (self-reported)	0.6	1.0	1.8	1.3	-0.4
Depression (self-reported)	0.6	0.8	1.3	0.5	1.1
Impedance of arm (left)	0.6	2.6	3.7	-1.9	-1.2
Loud music exposure frequency	0.6	0.7	1.4	-1.2	0.0
Worry too long after embarrassment	0.6	1.0	1.8	-1.3	-0.5
Angina (self-reported)	0.6	0.8	1.4	1.2	0.5
Mean time to correctly identify matches	0.6	1.1	1.2	1.0	1.1
Handedness (chirality/laterality): Left-handed	0.6	0.7	0.9	0.7	-1.0
Qualifications: nursing, teaching	0.6	0.9	1.6	-0.4	1.3
Mineral and other dietary supplements	0.6	0.8	1.2	-0.6	-1.1
Average weekly champagne plus white wine intake	0.6	0.8	1.4	0.3	-1.2
Impedance of whole body	0.6	3.1	5.7	-2.4	-0.7
Bipolar Disorder (2018)	0.5	0.8	1.0	0.8	1.0
Schizophrenia vs Biploar Disorder	0.5	0.7	0.9	0.7	0.9
Age at First Birth	0.5	0.7	1.0	1.0	0.7
HbA1C	0.5	0.5	1.0	-1.0	0.0
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.1	-1.1	0.4
Type 2 Diabetes (T2D) (2018)	0.5	0.9	1.5	0.6	1.2
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.1	-0.2	-1.1
Medication: Co-codamol	0.5	0.6	0.7	-0.7	-0.8
Had other major operations	0.5	0.6	0.8	0.7	0.9
Qualifications: None of the above	0.5	1.0	1.6	1.2	0.7
Financial difficulties in last 2 years	0.5	0.6	0.9	1.0	0.6
Heart attack	0.5	0.7	1.3	-0.2	-1.1
Weight	0.5	2.4	4.6	2.2	0.3
Time employed in main current job	0.5	0.6	1.2	0.2	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	0.9	-0.6	-0.9
Breastfed as a baby	0.5	0.6	0.9	1.0	0.4
Hypothyroidism/myxoedema (self-reported)	0.5	1.1	1.9	1.4	0.5
Medication: Seretide 50 evohaler	0.5	0.6	1.0	-0.5	-1.0
Arm predicted mass (right)	0.5	2.7	4.8	2.2	0.8
Mood swings	0.5	0.9	1.8	1.3	0.1
Diabetes diagnosed by doctor	0.5	0.8	1.6	1.2	0.3
Friendships satisfaction	0.5	0.6	0.8	-0.9	-0.6
Medication for cholesterol	0.5	0.8	1.5	-0.4	-1.2
Asthma (self-reported)	0.5	1.0	1.2	0.9	1.1
Wears glasses or contact lenses	0.5	0.6	1.0	-0.4	1.0
Myopia	0.5	0.7	1.5	-0.1	1.2
Bipolar Disorder or Schizophrenia	0.4	1.0	1.7	1.3	0.6
Neuroticism (Nagel 2018)	0.4	0.9	1.1	1.0	0.9
Hypothyroidism (self reported)	0.4	0.8	1.6	1.3	0.2
Allergy	0.4	0.9	1.1	-0.8	-1.1
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.1	-0.0	-1.1
Medication: Ramipril	0.4	0.5	0.7	0.6	0.8
Alcohol intake versus 10 years previously	0.4	0.6	0.6	0.7	0.8
Happiness	0.4	0.4	0.6	-0.8	-0.5
Arm fat-free mass (right)	0.4	2.2	4.0	2.0	0.6
Qualifications: College or University degree	0.4	1.2	1.3	-1.2	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	0.5	0.7	0.6
Chest pain or discomfort	0.4	0.6	1.1	-0.3	1.1
Age at last live birth	0.4	0.6	1.2	-1.1	0.1
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.7	0.4	0.8
Illnesses of siblings: Diabetes	0.4	0.4	0.6	0.8	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	1.3	1.1	0.7
Average weekly red wine intake	0.4	0.6	1.1	-1.1	0.1
Commuting to job workplace: Walk	0.4	0.4	0.6	-0.5	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.0	-0.0	1.0
Osteoarthritis (self-reported)	0.4	0.6	1.1	0.3	-1.1
Commuting to job workplace: Public transport	0.4	0.5	1.1	-1.0	0.1
Commuting to job workplace: Cycle	0.4	0.4	0.7	-0.8	-0.4
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.0	-0.2	-1.0
Neuroticism	0.3	0.7	1.2	0.6	1.1
Hair Pigment	0.3	7.2	11.9	-1.6	-3.5
Average weekly spirits intake	0.3	0.3	0.6	0.8	0.3
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.4	-0.6	-0.6
Body mass index (BMI)	0.3	1.3	2.6	1.6	-0.1
Asthma	0.3	0.5	0.7	0.5	0.9
Illnesses of mother	0.3	0.3	0.6	0.3	-0.7
Arm fat mass (right)	0.3	1.3	2.6	1.6	-0.2
Glaucoma (self-reported)	0.3	0.3	0.5	0.4	0.7
Birth weight	0.3	0.7	0.7	0.8	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.8	0.9	0.2
Heart disease (mother)	0.3	0.4	0.6	0.8	-0.4
Loneliness, isolation	0.3	0.4	0.6	-0.5	-0.8
Illnesses of father: None of the above (group 1)	0.3	0.3	0.6	0.8	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.2	-1.1	0.0
Arm fat mass (left)	0.3	1.2	2.4	1.5	-0.3
Risk taking	0.3	0.5	1.0	0.2	-1.0
Diastolic blood pressure, automated reading	0.3	0.8	1.5	-0.3	1.2
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.8	0.9	0.2
Depressed Affect (Nagel 2018)	0.2	0.3	0.5	0.4	-0.7
Schizophrenia (2018)	0.2	0.5	1.0	1.0	0.0
Schizophrenia (2014)	0.2	0.5	0.9	0.9	0.2
Blood Eosinophil Count	0.2	1.2	1.5	1.2	1.0
Blood Platelet Count	0.2	1.9	3.0	1.0	1.7
Respiratory disease	0.2	0.5	0.8	0.9	0.5
Relative age of first facial hair	0.2	0.5	0.9	-1.0	0.1
Average weekly fortified wine intake	0.2	0.3	0.3	-0.6	-0.4
Fed-up feelings	0.2	0.4	0.5	0.7	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.4	0.6	0.3
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.4	0.6	0.7
Chronic bronchitis/emphysema (father)	0.2	0.2	0.2	0.5	0.3
Impedance of arm (right)	0.2	1.1	1.9	-1.4	-0.5
Arm fat percentage (right)	0.2	0.9	1.7	1.3	-0.3
Standing height	0.2	1.6	2.6	1.6	0.8
Hair/balding pattern: Pattern 4	0.2	0.5	0.6	0.8	0.6
Blood clot in the leg (DVT)	0.2	0.3	0.5	0.7	0.2
Headache pain in last month	0.2	0.4	0.4	0.6	0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.3	-0.4	-0.6
Leg fat mass (right)	0.2	0.6	1.3	1.1	0.1
Supplements: Vitamin C	0.2	0.3	0.3	-0.6	-0.4
Arm fat percentage (left)	0.2	0.7	0.8	0.9	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.6	-0.8	0.2
Back pain experienced in last month	0.2	0.4	0.7	0.8	0.1
Hearing aid user	0.2	0.2	0.3	-0.3	-0.6
Medication: Atorvastatin	0.2	0.2	0.2	0.5	0.4
Illnesses of father: High blood pressure	0.2	0.3	0.5	0.1	-0.7
Pain experienced in last month	0.2	0.4	0.7	-0.8	-0.2
Leg fat mass (left)	0.2	0.7	1.4	1.2	0.1
Breast Cancer	0.1	0.3	0.5	-0.2	-0.7
Coronary Artery Disease (CAD)	0.1	0.2	0.3	0.5	-0.2
HDL Cholesterol	0.1	0.2	0.2	-0.5	0.3
BMI	0.1	0.6	0.7	0.9	-0.7
Waist Hip Ratio (WHR)	0.1	0.7	1.1	-1.1	0.4
Allergy or Eczema	0.1	0.2	0.4	0.6	-0.2
Lung FEV1/FVC ratio	0.1	0.5	0.8	-0.9	-0.3
Tanning	0.1	1.5	1.8	1.4	-1.0
Sensitivity / hurt feelings	0.1	0.1	0.1	0.2	-0.4
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.3	0.1	0.6
Medication for hormone replacement therapy	0.1	0.2	0.3	0.5	0.3
Supplements: Zinc	0.1	0.2	0.2	0.4	0.4
Pack years adult smoking proportion	0.1	0.2	0.4	0.2	-0.7
Trunk fat percentage	0.1	0.5	1.0	0.2	-1.0
Maternal smoking around birth	0.1	0.1	0.1	0.3	0.4
Age when periods started (menarche)	0.1	0.2	0.3	0.3	0.5
Medication: Levothyroxine sodium	0.1	0.1	0.2	0.4	0.3
Sitting height	0.1	0.5	1.0	1.0	-0.2
High blood pressure (mother)	0.1	0.2	0.3	-0.1	0.5
Trunk fat mass	0.1	0.5	0.8	0.9	-0.5
Waist circumference	0.1	0.5	1.0	1.0	0.1
Number of incorrect matches in round	0.1	0.2	0.2	0.5	0.3
Hearing difficulty/problems with background noise	0.1	0.1	0.2	-0.2	-0.4
Hair/balding pattern: Pattern 3	0.1	0.1	0.2	-0.1	-0.4
Pulse wave Arterial Stiffness index	0.1	0.1	0.1	-0.2	0.4
Length of working week for main job	0.1	0.2	0.3	0.6	-0.1
Gout (self-reported)	0.1	0.2	0.2	-0.4	-0.4
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.2	0.4	-0.5
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	0.2	0.4
Body fat percentage	0.1	0.3	0.5	0.3	-0.7
Number of children fathered	0.1	0.1	0.3	0.1	-0.5
Pulse wave peak to peak time	0.1	0.1	0.3	0.5	-0.2
Medication: Blood pressure	0.1	0.2	0.3	0.1	0.6
Medication: Omeprazole	0.1	0.2	0.2	0.4	0.4
Whole body fat mass	0.1	0.6	1.1	1.0	-0.3
Number of full sisters	0.1	0.2	0.3	0.5	-0.3
Leg pain on walking	0.1	0.1	0.2	0.5	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.2	0.4	-0.4
Knee pain experienced in last month	0.1	0.2	0.3	0.3	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.2	0.3	0.5	-0.1
Smoking status: Current	0.1	0.1	0.2	-0.5	0.0
Miserableness	0.1	0.1	0.2	0.5	-0.1
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.3	-0.4
Eye problems/disorders: Glaucoma	0.1	0.2	0.2	0.2	0.5
Irritability	0.1	0.1	0.1	-0.3	0.2
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.1	-0.4	-0.3
Pack years of smoking	0.1	0.2	0.4	-0.0	-0.6
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	0.0	0.1
Primary Biliary Cirrhosis	0.0	0.0	0.0	-0.1	0.0
Blood Red Count	0.0	0.2	0.5	0.2	0.7
Height	0.0	0.1	0.3	-0.5	0.0
Lung FVC	0.0	0.2	0.3	-0.0	-0.6
Current tobacco smoking	0.0	0.0	0.1	-0.3	-0.1
Tinnitus: Yes, but not now, but have in the past	0.0	0.1	0.1	-0.3	0.1
Supplements: Glucosamine	0.0	0.0	0.0	0.0	-0.0
Had menopause	0.0	0.0	0.0	0.1	-0.0
Forced vital capacity (FVC)	0.0	0.1	0.2	0.5	0.1
Medication: Simvastatin	0.0	0.0	0.0	0.2	0.1
Forced expiratory volume in 1-second (FEV1)	0.0	0.0	0.1	0.1	0.3
Medication: Cholesterol lowering	0.0	0.0	0.0	0.2	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.2	0.0	0.4
Peak expiratory flow (PEF)	0.0	0.1	0.1	-0.1	-0.3
Forced vital capacity (FVC), Best measure	0.0	0.0	0.1	0.3	0.1
Leg fat percentage (right)	0.0	0.0	0.0	-0.1	-0.2
Exposure to tobacco smoke outside home	0.0	0.1	0.1	0.2	0.3
Comparative height size at age 10	0.0	0.2	0.4	0.6	-0.3
Medication: Aspirin	0.0	0.0	0.0	-0.0	0.2
Medication: Aspirin	0.0	0.0	0.0	0.1	0.2
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.1	-0.1	0.3
High cholesterol (Self-reported)	0.0	0.0	0.0	-0.2	0.2
Leg fat percentage (left)	0.0	0.1	0.1	-0.2	-0.3
Average weekly beer plus cider intake	0.0	0.0	0.0	0.1	-0.1

Hub : Genes

INSL5

Models

Trait associations