Hub : Genes

INTS4L1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.0930 0.0400 1.7e-06 0.041 NA 0.061 NA 0.065 2.5e-04 NA 9.3e-06 NA 5.2e-06
2 GTEx Adipose Visceral Omentum 0.9160 0.0130 6.1e-16 0.055 NA -0.003 NA 0.005 8.0e-04 NA 5.2e-01 NA 1.8e-01
3 GTEx Adrenal Gland 0.1059 0.0592 5.6e-03 0.053 NA 0.054 NA 0.036 5.8e-03 NA 5.3e-03 NA 1.9e-02
4 GTEx Artery Aorta 0.8970 0.0200 2.2e-11 0.003 NA 0.014 NA 0.057 2.1e-01 NA 5.1e-02 NA 4.3e-04
5 GTEx Brain Caudate basal ganglia 0.7400 0.0720 8.0e-10 0.139 NA 0.102 NA 0.143 8.4e-05 NA 7.6e-04 NA 6.7e-05
6 GTEx Brain Cerebellar Hemisphere 0.2480 0.0990 1.1e-06 0.241 NA 0.244 NA 0.258 7.3e-07 NA 5.8e-07 NA 2.6e-07
7 GTEx Brain Cerebellum 0.4110 0.1210 1.7e-07 0.313 NA 0.268 NA 0.303 6.1e-10 NA 1.5e-08 NA 1.3e-09
8 GTEx Brain Cortex 0.4440 0.1030 3.3e-09 0.366 NA 0.372 NA 0.393 5.0e-11 NA 3.2e-11 NA 6.7e-12
9 GTEx Brain Frontal Cortex BA9 0.1752 0.0769 4.1e-05 0.142 NA 0.145 NA 0.144 1.4e-04 NA 1.2e-04 NA 1.3e-04
10 GTEx Brain Hypothalamus 0.0850 0.0460 7.9e-03 0.149 NA 0.026 NA 0.060 2.4e-04 NA 8.1e-02 NA 1.6e-02
11 GTEx Brain Nucleus accumbens basal ganglia 0.5580 0.1680 1.2e-05 0.086 NA 0.055 NA 0.049 2.7e-03 NA 1.4e-02 NA 1.9e-02
12 GTEx Brain Putamen basal ganglia 0.8290 0.0770 2.1e-08 0.037 NA 0.015 NA 0.092 4.7e-02 NA 1.4e-01 NA 3.5e-03
13 GTEx Breast Mammary Tissue 0.7970 0.0450 6.7e-09 -0.005 NA -0.003 NA -0.001 7.4e-01 NA 5.4e-01 NA 3.6e-01
14 GTEx Breast Mammary Tissue (Male) 0.0722 0.0631 9.1e-02 0.010 NA -0.011 NA 0.007 1.8e-01 NA 6.8e-01 NA 2.2e-01
15 GTEx Breast Mammary Tissue (Female) 0.6866 0.0925 2.2e-04 0.026 NA 0.014 NA -0.009 5.6e-02 NA 1.2e-01 NA 8.1e-01
16 GTEx Colon Sigmoid 0.1900 0.0740 2.1e-04 0.066 NA 0.178 NA 0.145 2.3e-03 NA 7.0e-07 NA 8.4e-06
17 GTEx Colon Transverse 0.8840 0.0220 5.6e-17 0.036 NA 0.027 NA -0.004 7.5e-03 NA 1.9e-02 NA 5.7e-01
18 GTEx Esophagus Gastroesophageal Junction 0.8560 0.0320 2.2e-10 0.001 NA -0.008 NA -0.007 3.0e-01 NA 8.8e-01 NA 6.9e-01
19 GTEx Esophagus Mucosa 0.8020 0.0380 7.7e-12 0.057 NA 0.075 NA 0.040 1.2e-04 NA 9.7e-06 NA 1.0e-03
20 GTEx Esophagus Muscularis 0.6540 0.0930 4.6e-06 0.029 NA 0.013 NA 0.032 6.9e-03 NA 5.3e-02 NA 4.9e-03
21 GTEx Heart Atrial Appendage 0.8880 0.0210 1.1e-16 0.057 NA 0.001 NA 0.184 1.5e-03 NA 2.7e-01 NA 1.1e-08
22 GTEx Heart Left Ventricle 0.8659 0.0215 1.3e-13 0.090 NA 0.024 NA 0.032 1.7e-05 NA 1.8e-02 NA 7.6e-03
23 GTEx Liver 0.9380 0.0160 3.1e-11 -0.009 NA -0.009 NA 0.029 7.2e-01 NA 7.0e-01 NA 5.4e-02
24 GTEx Lung 0.8925 0.0157 0.0e+00 0.016 NA 0.010 NA 0.008 1.9e-02 NA 5.4e-02 NA 7.9e-02
25 GTEx Muscle Skeletal 0.8461 0.0223 7.7e-15 0.039 NA 0.041 NA 0.005 9.0e-05 NA 6.2e-05 NA 9.0e-02
26 GTEx Nerve Tibial 0.8356 0.0347 4.7e-14 0.022 NA -0.004 NA 0.006 1.0e-02 NA 9.8e-01 NA 1.1e-01
27 GTEx Ovary 0.1830 0.0800 4.1e-04 0.098 NA 0.103 NA 0.095 2.2e-03 NA 1.7e-03 NA 2.5e-03
28 GTEx Pancreas 0.8680 0.0290 2.4e-07 0.018 NA 0.025 NA 0.054 5.6e-02 NA 3.1e-02 NA 2.6e-03
29 GTEx Pituitary 0.9490 0.0140 2.8e-09 -0.012 NA 0.062 NA 0.062 8.7e-01 NA 1.2e-02 NA 1.2e-02
30 GTEx Prostate 0.1550 0.0660 1.3e-04 0.114 NA 0.024 NA 0.081 8.8e-04 NA 8.1e-02 NA 4.5e-03
31 GTEx Skin Not Sun Exposed Suprapubic 0.9160 0.0100 1.9e-15 0.014 NA 0.065 NA 0.002 5.4e-02 NA 1.9e-04 NA 2.3e-01
32 GTEx Skin Sun Exposed Lower leg 0.1010 0.0310 1.5e-13 0.149 NA 0.159 NA 0.163 2.3e-12 NA 4.1e-13 NA 1.9e-13
33 GTEx Small Intestine Terminal Ileum 0.2190 0.0750 1.3e-05 0.268 NA 0.205 NA 0.168 1.0e-06 NA 2.4e-05 NA 1.4e-04
34 GTEx Stomach 0.1320 0.0450 7.3e-08 0.108 NA 0.110 NA 0.105 7.6e-06 NA 6.3e-06 NA 1.0e-05
35 GTEx Testis 0.6750 0.0690 0.0e+00 0.529 NA 0.637 NA 0.612 3.5e-27 NA 6.6e-36 NA 1.1e-33
36 GTEx Thyroid 0.1450 0.0480 1.1e-10 0.132 NA 0.174 NA 0.164 2.8e-10 NA 2.8e-13 NA 1.5e-12
37 ROSMAP Brain Pre-frontal Cortex 0.2694 0.0680 0.0e+00 0.327 0.292 0.305 0.313 0.322 3.9e-43 6.4e-38 8.0e-40 6.1e-41 2.0e-42
38 TCGA Bladder Urothelial Carcinoma 0.0650 0.0410 3.4e-06 0.050 0.048 0.038 NA 0.041 4.4e-05 6.0e-05 3.6e-04 NA 2.2e-04
39 TCGA Breast Invasive Carcinoma 0.0174 0.0111 2.1e-04 0.010 0.014 0.014 NA 0.011 3.0e-03 5.4e-04 4.7e-04 NA 1.9e-03
40 TCGA Kidney Renal Clear Cell Carcinoma 0.0840 0.0429 1.0e-04 0.020 0.041 0.036 NA 0.039 2.3e-03 1.8e-05 5.2e-05 NA 3.2e-05
41 TCGA Kidney Renal Papillary Cell Carcinoma 0.0980 0.0480 6.8e-06 0.070 0.040 0.074 NA 0.023 7.5e-05 2.5e-03 5.1e-05 NA 1.7e-02
42 TCGA Brain Lower Grade Glioma 0.0507 0.0333 2.7e-04 0.014 0.012 0.005 NA 0.014 9.1e-03 1.3e-02 7.0e-02 NA 9.5e-03
43 TCGA Lung Squamous Cell Carcinoma 0.0452 0.0251 8.4e-04 0.031 0.018 0.034 NA 0.030 1.5e-04 3.7e-03 7.9e-05 NA 2.1e-04
44 TCGA Prostate Adenocarcinoma 0.0367 0.0255 2.3e-03 0.026 0.012 0.010 NA 0.018 9.0e-04 1.7e-02 2.7e-02 NA 5.3e-03
45 TCGA Soft Tissue Sarcoma 0.0400 0.0260 3.7e-03 0.027 0.015 0.009 NA 0.015 9.5e-03 4.3e-02 9.5e-02 NA 3.9e-02
46 TCGA Skin Cutaneous Melanoma 0.1530 0.0900 4.5e-04 0.111 0.116 0.087 NA 0.094 6.8e-04 5.3e-04 2.5e-03 NA 1.8e-03
47 TCGA Testicular Germ Cell Tumors 0.1220 0.0690 9.3e-04 0.058 0.009 -0.007 NA 0.016 4.3e-03 1.4e-01 7.5e-01 NA 8.8e-02
48 TCGA Thyroid Carcinoma 0.0340 0.0200 3.8e-04 0.017 0.031 0.023 NA 0.024 7.7e-03 5.3e-04 2.6e-03 NA 2.0e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48
Bipolar Disorder (2018) 2.7 4.3 14.7 2.1 2.9 0.7 0.4 2.5 2.1 2.4 1.5 2.5 2.0 2.3 2.0 1.7 1.6 -1.1 1.4 2.0 2.6 2.1 2.2 3.5 1.8 2.8 0.0 2.1 2.3 2.5 0.2 3.8 2.3 0.0 2.5 1.9 2.2 2.2 1.8 1.9 2.1 2.1 1.9 1.3 1.8 1.6 2.1 2.1 1.8 2.1 1.8
Bipolar Disorder or Schizophrenia 0.7 1.7 8.2 1.1 2.3 -0.5 -0.2 1.4 1.1 1.4 0.8 1.2 1.0 1.5 1.5 1.2 1.6 0.4 1.2 1.0 1.7 1.0 1.4 2.3 0.4 1.1 0.0 1.3 1.0 1.2 0.3 2.9 1.3 0.0 1.3 1.1 1.3 1.1 0.9 1.2 1.4 1.3 1.8 0.6 1.1 1.6 1.5 1.3 1.1 1.4 1.1
Depressed Affect (Nagel 2018) 0.3 0.6 2.5 1.3 -0.9 -0.1 -0.5 0.8 0.5 0.3 0.9 1.2 0.5 0.8 0.6 0.9 0.0 1.2 0.3 0.5 0.3 0.8 0.7 0.3 -0.2 0.0 0.0 0.5 0.4 0.7 -0.4 0.3 1.6 0.0 1.3 1.3 1.1 1.1 0.9 0.6 0.8 0.6 1.4 0.4 0.8 1.0 1.1 0.9 0.6 1.0 0.7
Depression (Nagel 2018) 0.5 0.7 6.1 1.1 -2.2 0.3 -1.8 0.1 -0.6 -0.9 0.3 0.2 -0.2 0.4 0.5 0.8 0.0 -0.2 0.9 -0.2 -0.9 -0.0 0.2 -0.4 -1.1 -0.4 0.0 -0.2 -0.2 0.1 -1.8 1.3 1.1 0.0 0.4 1.3 0.7 0.5 0.8 -0.3 0.4 0.1 2.5 0.8 0.8 -0.1 1.2 0.7 0.4 1.1 0.8
Intelligence (Savage-Jansen 2018) 0.1 0.2 1.7 -0.6 0.2 -0.1 1.0 0.8 0.3 0.2 -0.3 -0.0 -0.1 0.6 1.3 -0.5 -0.6 -0.5 0.1 -0.1 0.4 0.5 0.1 0.2 0.3 0.6 0.0 -0.2 0.7 0.0 0.8 -0.5 -0.3 0.0 -0.2 -0.3 -0.3 -0.1 -0.3 0.1 0.1 0.0 -0.4 0.0 -0.1 -0.2 -0.2 -0.1 0.1 -0.1 -0.0
Neuroticism (Nagel 2018) 0.3 0.6 2.2 1.3 -1.1 -0.4 -0.6 0.5 0.3 -0.0 0.8 1.1 0.5 0.7 0.7 0.7 0.1 0.6 0.3 0.5 0.4 0.4 0.7 1.2 -0.0 0.1 0.0 0.4 0.4 0.8 -1.1 0.8 1.2 0.0 0.9 1.2 0.9 0.9 0.9 0.4 0.7 0.7 1.5 1.1 1.0 -0.2 1.0 0.9 0.8 0.8 0.9
Schizophrenia (2018) 0.1 0.2 1.7 -0.3 0.7 -1.2 -0.6 -0.3 -0.2 -0.2 -0.2 -0.5 -0.3 0.1 0.3 0.2 0.7 1.3 0.3 -0.3 0.1 -0.4 0.1 0.2 -0.9 -0.7 0.0 -0.0 -0.5 -0.3 0.2 0.7 -0.2 0.0 -0.3 -0.1 -0.0 -0.4 -0.2 0.0 0.0 -0.0 0.6 -0.2 -0.1 0.8 0.1 -0.0 -0.1 0.1 -0.1
Schizophrenia vs Biploar Disorder 1.0 1.4 3.9 -1.5 0.4 -0.6 1.6 -1.1 -0.6 -0.3 -0.4 -1.2 -1.1 -1.2 -1.1 -0.6 -0.5 1.5 -1.3 -1.1 -0.3 -0.7 -0.3 -0.6 0.7 -0.3 0.0 -0.8 -0.9 -1.1 2.0 -1.5 -1.8 0.0 -1.8 -1.7 -1.4 -1.2 -1.0 -0.4 -1.0 -1.4 -1.9 -1.7 -1.7 0.4 -1.4 -1.4 -1.2 -1.5 -1.5
Worry (Nagel 2018) 0.3 0.6 1.8 1.0 1.0 0.2 0.0 0.5 0.3 0.2 0.9 0.7 0.5 0.7 0.5 1.3 1.0 0.4 0.7 0.5 1.2 0.5 0.8 1.3 0.8 1.0 0.0 0.6 0.6 0.7 -0.4 1.0 0.7 0.0 0.7 1.1 0.9 0.9 0.9 0.5 0.7 0.5 1.2 0.8 0.9 0.4 0.8 0.8 0.7 0.9 0.8
Alzheimer’s Disease (in mother) 1.1 1.3 5.4 -0.8 -1.5 -1.3 -0.3 -1.1 -1.6 -1.4 -1.4 -1.1 -1.4 -0.7 -0.1 -1.2 -0.7 0.4 -0.4 -1.4 -1.7 -1.6 -1.2 -0.7 -2.3 -1.7 0.0 -1.5 -1.3 -1.4 0.2 0.8 -0.3 0.0 -0.4 -0.5 -0.9 -1.3 -1.2 -1.5 -1.2 -1.3 0.6 -1.2 -1.1 0.1 -0.8 -1.1 -1.4 -0.9 -1.2
Alzheimer’s Disease (in father) 0.4 0.4 2.6 0.5 0.1 0.1 -1.6 -0.9 0.2 -0.2 0.6 0.1 0.3 -0.2 -1.0 0.6 1.3 -1.3 -0.3 0.3 -0.7 -0.1 0.5 -0.2 -0.4 -1.2 0.0 0.6 -0.7 0.5 -1.4 -0.6 0.1 0.0 -0.2 0.2 0.4 0.2 0.7 0.4 0.4 0.8 0.8 0.8 0.8 -0.4 0.6 0.4 0.6 0.5 0.6
Alzheimer’s Disease (including proxy) 0.7 1.1 3.3 -0.7 -0.9 -1.2 -1.0 -1.8 -1.5 -1.5 -1.1 -1.1 -1.3 -1.0 -1.3 -0.5 -0.3 -0.4 -0.9 -1.3 -1.8 -1.7 -0.8 -0.6 -1.6 -1.6 0.0 -1.2 -1.6 -0.8 -0.4 0.4 -0.5 0.0 -0.7 -0.7 -0.9 -1.2 -0.8 -1.3 -1.1 -0.8 0.5 -0.5 -0.7 -0.7 -0.8 -1.1 -1.0 -0.9 -0.9
Crohns Disease (2017) 0.4 0.9 3.3 1.3 0.4 1.1 -0.8 0.5 0.8 0.7 1.4 0.8 0.6 0.6 0.2 1.1 1.2 -0.0 1.8 0.6 0.6 0.7 0.6 1.0 0.2 0.1 0.0 0.8 0.8 0.7 -0.5 1.3 1.5 0.0 1.5 1.5 1.4 0.9 0.7 1.0 1.0 1.2 1.2 0.8 1.1 0.9 0.6 1.1 0.9 1.2 0.9
Irritable Bowel Disease (IBD) 0.2 0.4 3.8 0.4 -0.8 0.8 -0.5 0.0 0.0 0.1 0.5 0.2 0.0 0.1 -0.1 0.6 1.2 -0.5 1.7 0.1 -0.9 -0.1 0.1 0.8 -0.3 -0.6 0.0 0.2 -0.4 -0.0 0.0 1.9 0.5 0.0 0.4 0.8 0.6 0.2 0.2 0.2 0.3 0.1 1.4 -0.3 0.2 1.5 0.7 0.5 -0.0 0.6 0.1
Ulcerative Colitis (UC) 0.2 0.3 2.2 -0.0 -1.5 0.4 -0.3 -0.1 -0.2 -0.1 0.1 -0.0 -0.0 0.1 0.1 0.3 1.0 -0.8 1.3 0.0 -1.5 -0.2 0.1 0.5 -0.6 -0.8 0.0 0.1 -0.7 -0.1 0.1 1.2 -0.1 0.0 -0.3 0.2 0.1 0.0 0.3 -0.2 0.1 -0.2 1.1 -0.7 -0.3 1.3 0.9 0.2 -0.3 0.3 -0.1
Major Depression (MDD) 1.3 1.5 12.1 0.5 2.8 -0.1 -0.9 0.9 -0.0 -0.2 0.6 0.6 0.4 1.5 1.9 1.6 0.3 -0.7 0.3 0.4 1.9 0.5 0.8 3.5 1.5 2.2 0.0 0.5 1.3 0.9 -1.2 1.4 0.5 0.0 0.0 0.9 0.4 0.7 0.5 0.3 0.9 1.1 1.9 2.1 1.6 -1.4 1.2 1.0 1.2 1.2 1.5
Reaction Time 0.4 0.8 3.1 1.0 0.2 1.5 -1.2 0.6 0.4 0.2 0.7 0.4 0.8 0.7 -0.4 1.8 1.3 1.0 1.0 0.8 0.3 0.7 0.9 0.3 0.7 1.1 0.0 0.9 0.4 0.7 -0.3 0.5 1.1 0.0 1.0 1.3 1.0 1.2 1.1 0.6 0.7 0.8 1.8 0.4 0.9 1.2 1.2 1.0 0.6 1.1 0.7
Verbal and Numeric Reasoning (VNR) 0.2 0.4 2.4 0.1 0.8 -0.0 0.2 0.9 0.7 0.6 0.4 0.5 0.3 0.7 1.6 -0.8 -0.5 -1.0 0.1 0.3 1.0 0.7 0.4 0.7 0.4 0.5 0.0 0.3 1.2 0.7 -0.2 -0.2 0.3 0.0 0.3 0.2 0.3 0.1 0.4 0.7 0.7 0.8 -0.3 1.3 0.9 -1.1 0.3 0.4 1.0 0.4 0.9
Breast Cancer 1.3 3.2 11.7 -1.9 -2.3 -0.8 0.5 -2.0 -2.2 -2.4 -1.6 -2.0 -2.1 -1.4 -0.8 -1.3 -1.3 -0.1 -1.2 -2.1 -3.4 -2.2 -1.5 -1.0 -1.0 -1.6 0.0 -2.2 -1.9 -2.1 0.6 -1.3 -1.9 0.0 -2.4 -1.7 -2.2 -1.9 -1.8 -2.1 -2.0 -2.1 -0.5 -2.2 -2.0 0.2 -1.7 -1.9 -2.3 -1.6 -2.1
Ovarian Cancer 0.2 0.3 1.4 -0.6 0.6 0.6 0.2 -0.2 -0.8 -1.0 -0.8 -0.7 -0.7 0.2 0.6 -0.1 -1.0 -0.9 -0.2 -0.7 -0.3 -0.3 0.1 0.3 -0.3 0.5 0.0 -0.8 0.3 0.2 -0.3 0.1 -0.4 0.0 -0.6 -0.3 -0.8 -0.2 -0.0 -0.8 -0.4 -0.2 0.4 0.4 -0.1 -1.2 -0.5 -0.5 -0.2 -0.5 -0.1
Prostate Cancer 0.2 0.2 3.5 0.5 1.0 0.2 0.5 0.3 -0.4 -0.1 -0.7 -0.3 -0.0 -0.2 -0.1 -0.2 0.4 1.0 0.2 -0.0 1.3 -0.1 0.3 -0.1 0.9 0.3 0.0 -0.1 0.9 0.2 0.3 1.9 0.0 0.0 0.2 0.2 0.1 0.1 -0.1 -0.3 -0.1 -0.2 0.8 0.2 0.2 -0.2 -0.0 -0.1 -0.0 0.0 0.0
Age at First Birth 2.7 3.9 8.0 2.4 1.8 2.0 -0.8 2.1 2.7 2.8 2.1 2.8 2.4 2.2 1.2 1.4 1.5 0.1 1.2 2.4 2.0 2.3 2.3 -0.7 -1.2 0.8 0.0 2.6 1.9 2.4 -0.5 0.7 2.7 0.0 2.8 2.0 2.3 2.2 2.4 2.7 2.5 2.2 0.8 1.3 1.8 1.4 2.0 2.1 2.2 2.0 2.0
Bipolar Disorder (2011) 0.2 0.2 3.8 -0.2 0.7 0.3 0.3 0.1 0.2 0.4 -0.0 0.3 -0.0 0.2 0.1 -0.0 -0.3 -2.0 -0.7 0.0 0.1 0.4 -0.1 1.4 0.6 0.1 0.0 0.1 -0.0 0.3 0.2 0.8 0.0 0.0 0.2 -0.1 0.1 0.1 -0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.2 0.2 2.0 0.4 0.2 0.3 -1.4 -0.6 -0.7 -0.7 -0.1 -0.3 -0.4 -0.3 -0.8 -0.1 -1.1 -0.2 0.4 -0.4 -0.9 -0.4 0.0 0.2 -0.2 -0.2 0.0 -0.6 -0.7 0.2 -0.8 0.8 0.2 0.0 0.0 0.5 0.1 0.1 0.3 -0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Coronary Artery Disease (CAD) 0.2 0.2 1.7 0.6 0.8 0.3 0.6 0.1 0.1 0.3 0.4 0.7 0.3 0.4 -0.4 0.9 1.3 0.8 0.5 0.2 0.4 -0.1 0.3 0.4 1.2 -0.6 0.0 0.3 0.0 -0.1 0.7 1.2 0.3 0.0 0.3 0.4 0.5 0.1 -0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 2.5 4.0 7.4 2.6 1.1 1.2 -1.2 1.7 2.4 2.2 2.4 2.5 2.0 1.7 0.9 1.8 1.5 -0.0 1.7 2.0 2.1 2.0 2.3 1.1 1.2 1.1 0.0 2.2 2.3 2.6 -1.3 1.0 2.4 0.0 2.5 2.5 2.6 2.3 2.3 2.4 2.5 2.7 1.8 2.1 2.5 1.0 1.7 2.4 2.4 2.5 2.3
Mean Putamen Volume 0.4 0.4 2.4 -0.8 -0.2 0.3 1.4 -0.6 -0.3 -0.2 -0.5 -0.8 -0.6 -0.6 -0.9 -0.1 0.1 0.2 0.7 -0.6 -0.4 -0.2 -0.4 -0.1 1.0 -0.3 0.0 -0.6 0.0 -0.5 0.8 -1.0 -0.3 0.0 -0.2 -0.4 -0.5 -0.5 -0.9 -0.3 -0.6 -0.8 -1.3 -0.8 -0.8 0.1 -1.5 -0.6 -0.7 -0.7 -0.8
Fasting Glucose 1.2 1.5 9.2 1.3 -2.2 1.9 -2.3 0.2 0.3 -0.0 0.4 0.9 0.7 0.7 0.1 -0.2 0.1 -1.2 0.5 0.5 1.0 0.1 1.0 3.0 0.1 0.5 0.0 0.5 0.6 0.8 -2.2 1.7 1.2 0.0 0.9 1.2 0.9 0.8 0.8 0.4 0.8 1.5 2.1 2.1 1.8 -1.2 1.3 1.2 1.2 1.3 1.5
HbA1C 1.6 1.7 9.0 1.3 -2.2 1.3 -0.6 1.9 0.9 0.7 0.6 0.8 1.2 1.6 1.5 1.1 0.5 0.6 1.5 1.1 0.5 1.3 0.8 1.4 -0.7 2.0 0.0 0.9 1.6 1.1 -1.3 3.0 1.2 0.0 1.0 1.3 0.8 1.4 1.6 1.0 1.3 1.5 1.8 1.8 1.7 -0.1 1.5 1.4 1.4 1.5 1.6
HDL Cholesterol 0.4 0.7 3.4 1.0 -1.0 1.3 -0.8 1.0 1.4 1.4 0.8 1.0 1.3 0.8 -0.0 0.8 1.4 0.1 1.1 1.2 -0.3 1.1 0.6 -1.3 -1.9 -0.1 0.0 1.3 0.1 0.6 -0.1 -0.5 1.0 0.0 1.4 0.8 1.2 0.8 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
LDL Cholesterol 0.4 0.6 2.9 -1.0 0.3 -0.7 1.3 -1.1 -0.5 -0.2 -0.6 -0.9 -0.7 -1.4 -1.6 -0.7 -1.0 0.4 -1.0 -0.6 0.5 -0.8 -1.3 -0.1 0.6 -1.7 0.0 -0.6 -1.1 -0.9 1.6 -0.5 -0.4 0.0 -0.2 -0.8 -0.6 -1.1 -1.2 -0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Lupus 0.5 0.8 2.4 0.7 1.5 0.5 -0.7 0.9 0.9 0.9 0.2 1.0 0.7 1.1 1.2 1.2 0.8 -1.3 0.4 0.7 0.4 0.6 0.2 1.4 -0.6 0.4 0.0 1.0 0.9 1.1 -0.2 0.6 1.6 0.0 1.5 1.2 1.0 0.6 1.1 0.8 0.8 0.9 0.5 1.0 1.0 -0.5 0.6 0.8 0.9 0.9 0.9
Neuroticism (2016) 0.1 0.2 2.7 0.2 0.6 0.0 0.1 -0.5 -0.4 -0.6 0.3 0.0 -0.3 -0.1 -0.2 1.6 1.1 1.0 -0.3 -0.4 0.1 -0.3 0.1 -0.6 -0.5 0.1 0.0 -0.1 -0.4 -0.2 -0.3 0.5 -0.1 0.0 -0.3 -0.1 -0.2 -0.2 -0.5 -0.3 -0.3 -0.3 0.0 0.1 -0.1 -0.7 0.0 -0.3 -0.1 -0.3 -0.0
Primary Biliary Cirrhosis 0.5 0.7 6.3 -0.2 0.4 -0.2 -0.3 0.3 -1.0 -0.9 -0.4 -0.3 -0.8 1.0 1.4 0.9 -0.3 2.0 0.9 -0.8 -0.1 -0.5 0.2 2.1 -0.2 1.4 0.0 -0.9 -0.2 -0.2 -0.2 2.5 0.2 0.0 -0.1 0.5 -0.1 -0.2 -0.8 -0.6 -0.0 -0.3 2.4 0.3 0.4 0.3 0.5 0.1 -0.1 0.5 0.2
Rheumatoid Arthritis 0.1 0.2 1.7 -0.4 0.5 0.2 0.9 0.2 0.2 0.3 -0.1 -0.1 0.1 -0.0 -0.6 0.4 0.5 1.3 1.0 0.1 0.6 0.3 0.0 0.0 0.5 0.2 0.0 0.0 0.3 -0.1 1.1 -1.1 0.0 0.0 0.3 -0.0 0.0 0.1 -0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Schizophrenia (2014) 0.2 0.5 3.2 -0.8 1.7 -1.4 0.7 -0.6 -0.3 -0.1 -0.5 -0.6 -0.4 -0.7 -1.0 0.3 1.0 1.8 0.1 -0.4 1.1 -0.4 0.0 1.0 1.1 0.0 0.0 -0.2 -0.6 -0.5 1.3 1.1 -0.8 0.0 -0.6 -0.7 -0.3 -0.5 -0.5 -0.2 -0.4 -0.4 -0.3 -0.9 -0.6 1.0 -0.5 -0.5 -0.6 -0.5 -0.7
Triglycerides 0.2 0.3 2.9 0.5 1.1 -0.4 -0.6 0.5 0.0 -0.2 0.4 0.3 0.4 0.6 1.0 -0.5 -1.7 0.0 -0.2 0.4 0.7 0.3 0.5 1.5 0.7 0.0 0.0 0.1 1.0 0.8 -0.9 0.1 0.7 0.0 0.2 0.8 0.4 0.5 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Type 2 Diabetes (T2D) (2012) 0.2 0.3 1.2 0.4 -0.7 0.7 0.0 0.6 0.8 0.8 0.8 0.7 0.7 0.6 0.1 0.2 -1.0 0.1 -0.7 0.7 0.4 0.9 0.4 -0.2 -0.2 1.1 0.0 0.6 0.1 0.7 -0.6 -0.1 0.5 0.0 0.6 0.3 0.5 0.5 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Ulcerative Colitis 0.3 0.5 2.6 0.6 -1.0 0.9 -0.5 0.3 0.3 0.5 0.3 0.6 0.5 0.5 0.2 -0.0 1.2 -1.3 1.6 0.5 -1.1 0.4 0.2 -0.1 -1.3 -0.7 0.0 0.5 -0.3 0.0 -0.1 1.2 0.7 0.0 0.6 0.7 0.7 0.4 0.2 0.3 0.5 0.4 1.3 -0.3 0.1 1.5 1.2 0.6 0.2 0.7 0.3
Blood Eosinophil Count 0.2 1.7 14.4 0.6 0.8 1.3 -3.3 -0.5 -0.8 -1.5 0.5 -0.3 -0.1 1.3 1.2 0.2 -0.4 -1.9 1.6 -0.1 -0.9 -0.3 0.5 1.7 -1.7 -0.1 0.0 -0.3 0.3 0.6 -3.8 0.1 0.4 0.0 -0.4 1.2 0.4 0.3 0.6 -0.3 0.6 0.8 2.9 2.3 1.9 -1.9 1.4 0.9 1.1 1.3 1.6
Blood Platelet Count 0.5 6.0 12.0 -2.8 -0.2 -1.3 2.1 -2.3 -3.2 -2.5 -2.1 -3.0 -3.0 -2.2 -2.0 -1.8 -1.8 2.3 -1.4 -3.0 -2.0 -2.8 -2.4 -1.2 -1.0 -0.7 0.0 -3.2 -3.4 -3.3 2.6 0.7 -2.4 0.0 -2.5 -2.5 -2.7 -2.7 -3.0 -3.0 -2.9 -3.3 -0.7 -3.5 -3.1 0.9 -2.6 -2.8 -3.4 -2.6 -3.2
Blood Red Count 0.1 1.0 4.8 0.5 2.2 0.2 0.0 0.3 1.3 1.0 1.2 0.8 1.1 1.1 0.4 -0.4 -1.7 -0.5 -1.2 1.1 0.8 1.0 0.5 1.2 -0.4 0.2 0.0 0.9 1.2 1.7 -0.8 -1.4 1.1 0.0 1.2 0.6 0.8 0.6 0.4 1.2 1.0 1.2 -0.3 1.5 1.1 -1.1 0.6 0.8 1.3 0.6 1.2
Blood White Count 0.5 3.4 38.3 1.0 -1.6 0.3 -2.4 1.0 -2.0 -2.7 0.5 -0.3 -0.7 2.3 3.3 3.1 0.4 2.0 3.4 -0.7 -1.8 -0.6 1.2 1.4 -1.9 2.9 0.0 -1.1 -0.3 -0.2 -1.8 3.0 0.6 0.0 -0.7 1.8 -0.0 1.0 0.9 -1.3 0.2 -0.4 6.2 -0.1 0.5 2.6 2.1 1.3 -0.5 2.0 0.6
Heel T-Score 0.3 2.8 6.9 1.8 1.8 0.6 -0.6 2.2 1.7 1.5 1.0 1.2 1.8 2.4 2.6 0.7 0.8 0.5 1.0 1.8 2.0 1.7 1.7 1.5 0.1 2.3 0.0 1.7 2.5 2.1 -0.9 1.4 1.6 0.0 1.5 1.8 1.7 1.7 2.0 1.7 2.0 1.8 1.8 1.7 1.8 0.9 2.0 2.1 1.9 2.1 2.0
BMI 0.1 0.8 5.6 0.4 -0.8 0.1 -2.1 0.0 -1.0 -1.6 0.1 -0.1 -0.6 1.1 1.3 0.1 -1.6 -0.3 1.0 -0.6 -0.8 -0.4 0.8 0.5 -1.0 1.1 0.0 -1.0 0.3 0.4 -2.4 0.5 0.4 0.0 -0.3 0.6 -0.2 0.2 0.2 -0.8 0.0 -0.1 2.2 1.5 1.2 -1.3 0.8 0.4 0.4 0.7 0.9
Height 0.6 12.0 24.3 -3.4 -4.0 -2.5 2.3 -3.1 -3.2 -2.7 -3.0 -3.0 -3.3 -4.6 -3.0 -4.9 -2.8 -4.9 -3.4 -3.3 -2.5 -2.8 -3.6 -3.6 1.5 -4.0 0.0 -3.5 -2.7 -3.9 1.2 -1.9 -4.3 0.0 -4.2 -4.7 -4.1 -3.6 -3.6 -3.3 -3.9 -3.5 -4.9 -2.4 -3.6 -3.9 -4.1 -4.0 -3.3 -4.2 -3.5
Waist Hip Ratio (WHR) 0.0 0.2 1.6 0.1 -0.7 -0.2 -1.2 0.5 0.3 0.3 0.1 0.2 0.3 0.2 0.7 0.1 0.8 0.9 -0.5 0.3 0.2 0.3 -0.2 -0.5 -1.3 0.5 0.0 0.5 -0.8 -0.0 -0.5 -0.2 -0.3 0.0 -0.3 -0.0 0.3 0.2 0.5 0.4 0.5 0.3 0.4 0.5 0.3 0.2 0.4 0.4 0.5 0.5 0.5
Systolic Blood Pressure 0.3 1.7 7.0 -1.4 -0.5 -1.1 0.7 -1.1 -0.9 -0.5 -1.2 -1.1 -1.2 -1.7 -0.9 -2.4 -1.2 -2.0 -2.6 -1.2 -0.9 -0.9 -1.6 -0.2 0.7 -1.0 0.0 -1.1 -0.9 -1.2 0.8 -0.8 -1.1 0.0 -1.1 -1.6 -1.4 -1.5 -1.4 -1.0 -1.3 -1.3 -2.6 -0.8 -1.3 -1.5 -1.7 -1.6 -1.1 -1.7 -1.2
Smoking Status 0.1 0.3 1.7 0.2 -1.1 1.3 -0.6 0.4 -0.2 -0.4 0.3 0.1 -0.1 0.3 0.7 -0.2 -1.0 -0.1 1.2 -0.1 -0.6 0.2 -0.1 -1.0 -0.7 0.2 0.0 -0.3 0.4 -0.1 -0.6 0.4 0.2 0.0 0.0 0.6 0.3 0.4 0.3 -0.0 0.1 -0.1 0.9 0.4 0.4 -0.1 0.5 0.4 0.1 0.5 0.4
Allergy or Eczema 0.9 2.3 5.3 2.2 -2.0 0.9 -1.2 1.4 1.8 1.9 1.7 2.0 1.9 0.7 -0.3 -0.2 0.6 -0.4 1.8 1.9 0.0 1.7 1.3 -1.3 -0.1 -0.3 0.0 1.6 0.6 1.3 -0.9 1.4 1.7 0.0 1.9 1.7 2.2 1.9 2.2 1.7 1.8 1.4 1.5 0.6 1.3 2.3 2.0 2.0 1.4 1.9 1.5
Cardiovascular Disease 0.1 0.3 2.1 -1.0 -0.7 -0.5 0.5 0.3 -0.4 -0.2 -0.7 -0.4 -0.4 0.3 0.5 0.3 0.7 0.5 0.7 -0.4 -0.8 -0.1 -0.2 1.5 0.2 1.0 0.0 -0.5 -0.2 -0.5 0.9 -0.3 -0.5 0.0 -0.4 -0.4 -0.4 -0.3 -0.4 -0.5 -0.5 -0.8 -0.1 -1.0 -0.5 1.1 -0.4 -0.4 -0.8 -0.4 -0.7
Hypothyroidism (self reported) 0.3 0.6 2.6 -0.4 -0.5 -0.1 -0.8 -0.9 -1.3 -1.2 -0.7 -0.7 -1.1 -0.1 0.2 -0.7 -0.7 -1.4 0.9 -1.1 -1.6 -1.2 -1.0 1.4 -0.9 -0.6 0.0 -1.2 -0.4 -0.5 -0.8 1.2 -0.1 0.0 -0.3 0.2 -0.4 -0.7 -0.7 -1.0 -0.5 -0.7 1.2 -0.1 -0.1 -0.4 -0.1 -0.3 -0.5 -0.1 -0.2
Respiratory disease 0.1 0.3 2.2 0.3 -0.9 0.9 -1.1 0.5 -0.5 -0.5 -0.3 0.0 -0.3 0.1 0.5 -0.5 -1.2 -0.3 -0.0 -0.3 -0.3 -0.0 -0.4 -0.4 -0.6 -0.3 0.0 -0.6 0.0 -0.5 -0.4 1.5 0.2 0.0 0.3 0.5 0.2 0.2 -0.0 -0.5 -0.0 -0.2 1.5 -0.1 0.1 0.7 0.4 0.2 -0.2 0.3 0.0
Type 2 Diabetes (T2D) (2018) 0.2 0.4 2.8 0.1 -0.3 -0.6 -0.6 -0.3 -0.8 -0.8 -0.5 -0.4 -0.3 0.3 -0.3 1.0 1.5 0.5 1.4 -0.3 -0.2 -0.6 0.4 0.6 0.2 0.9 0.0 -0.3 -0.4 -0.2 -0.0 1.7 -0.3 0.0 -0.3 0.1 -0.0 0.0 -0.2 -0.6 -0.3 -0.5 1.5 -0.3 0.0 0.9 0.4 0.1 -0.4 0.3 -0.1
Lung FEV1/FVC ratio 0.2 0.9 4.9 -0.4 0.1 -0.0 -0.6 -1.4 -1.9 -2.2 -1.6 -1.4 -1.2 -1.1 -0.9 0.6 0.2 -0.9 0.4 -1.2 -0.7 -1.5 -0.6 -0.8 -0.7 -1.1 0.0 -1.3 -0.3 -0.8 -0.5 0.1 -0.5 0.0 -0.8 -0.4 -1.0 -0.9 -0.7 -1.8 -1.4 -1.0 0.7 -0.5 -0.4 -1.2 -0.6 -0.9 -1.2 -0.7 -0.8
Lung FVC 1.2 6.0 16.9 2.4 2.3 1.5 0.3 3.6 3.4 3.5 1.9 2.9 3.1 2.5 2.8 1.4 1.5 -0.1 0.8 3.1 4.1 3.0 2.3 1.2 0.6 2.1 0.0 3.2 3.5 2.9 -0.0 1.8 3.0 0.0 3.5 2.3 2.7 2.6 2.1 3.1 2.8 3.0 0.3 2.4 2.2 0.4 2.1 2.5 2.9 2.2 2.5
Neuroticism 0.3 0.7 1.7 1.1 0.2 -0.7 -0.7 0.3 0.6 0.4 0.9 1.2 0.7 0.7 0.1 1.1 0.5 1.3 0.7 0.7 0.9 0.5 0.7 0.9 0.5 -0.0 0.0 0.7 0.2 0.7 -0.7 0.9 0.9 0.0 0.8 1.2 1.1 1.0 0.6 0.6 0.9 0.6 1.2 1.1 1.1 0.3 1.1 1.0 0.9 1.1 1.1
Chronotype (morning person) 0.2 0.5 2.9 -0.3 -0.1 0.7 -0.1 -0.9 -1.1 -1.1 -0.9 -0.9 -0.9 -0.2 -0.4 -0.7 0.1 -1.4 1.7 -0.9 -1.3 -1.0 -0.5 -0.3 -0.4 -1.3 0.0 -1.0 -0.1 -0.7 -0.3 0.2 0.3 0.0 -0.1 0.2 -0.4 -0.8 -0.5 -0.9 -0.7 -0.6 0.9 -0.0 0.1 -0.1 -0.3 -0.5 -0.6 -0.2 -0.3
Hair Pigment 0.0 0.6 2.9 1.0 0.2 1.2 -0.4 1.0 0.8 0.6 1.0 0.6 0.8 0.9 1.2 0.1 1.7 -0.6 -0.2 0.8 0.3 1.0 0.9 -0.5 0.4 -1.2 0.0 1.1 0.8 0.3 -0.8 0.0 -0.2 0.0 0.3 0.4 0.7 0.8 1.4 0.9 0.7 0.8 0.4 0.5 0.8 0.4 0.6 0.7 0.7 0.6 0.8
Tanning 0.1 0.9 2.8 1.0 1.0 0.8 -0.5 0.9 1.2 1.3 0.8 1.7 1.4 0.7 0.3 0.2 0.7 -1.5 -0.6 1.4 1.5 1.1 0.5 -0.5 -0.1 0.4 0.0 1.4 1.1 1.2 -0.6 0.9 1.0 0.0 1.2 0.6 0.9 1.0 0.5 1.0 0.9 1.3 -0.2 1.2 0.8 -0.7 0.8 0.8 1.2 0.7 1.0
Hand grip strength (left) 0.5 1.2 5.6 -0.9 -0.8 0.9 0.4 -1.2 -0.3 -0.3 -0.1 -0.2 -0.7 -1.6 -1.4 -1.3 -0.6 -1.7 -1.9 -0.7 -0.9 -0.5 -1.0 -2.1 -0.2 -1.9 0.0 -0.5 -0.8 -1.2 -0.0 -1.9 -1.3 0.0 -1.1 -1.4 -1.0 -0.9 -0.9 -0.5 -0.9 -0.7 -2.4 -0.5 -1.0 -1.3 -1.2 -1.1 -0.7 -1.2 -0.8
Number of treatments/medications taken 0.4 0.7 6.3 0.1 0.8 0.3 0.6 0.7 -0.1 0.1 -0.0 0.1 0.1 0.7 -0.2 2.1 0.3 2.5 1.4 0.1 0.6 0.4 0.6 0.9 1.2 1.7 0.0 -0.1 0.2 0.4 1.4 1.6 0.7 0.0 1.0 0.8 0.5 0.6 0.1 -0.1 0.0 -0.1 1.4 -0.5 0.2 1.7 0.5 0.3 -0.3 0.4 -0.1
Average weekly spirits intake 0.8 1.0 3.7 -0.8 -0.6 -0.8 0.5 -1.3 -1.3 -1.4 -1.0 -1.2 -1.1 -1.6 -1.7 -0.2 -1.1 1.9 -0.5 -1.1 -0.8 -1.1 -1.2 -1.1 0.4 -0.5 0.0 -1.3 -1.5 -1.1 0.5 -0.2 -1.2 0.0 -1.1 -0.7 -0.8 -0.9 -1.1 -1.2 -1.1 -1.0 0.0 -0.9 -0.6 -0.5 -0.8 -0.9 -1.2 -0.9 -1.0
Sensitivity / hurt feelings 0.1 0.2 1.8 0.4 -0.6 -1.0 -0.0 -0.6 -0.4 -0.3 0.5 0.1 0.0 -0.2 -0.8 -0.2 -1.0 0.2 -0.2 0.0 -0.0 -0.5 0.4 1.2 1.4 -0.1 0.0 -0.2 -0.5 0.3 -0.4 1.2 -0.0 0.0 -0.2 0.2 0.1 0.1 -0.0 -0.2 -0.1 -0.1 0.7 0.4 0.4 -0.0 0.2 0.2 0.0 0.3 0.2
Frequency of depressed mood in last 2 weeks 0.3 0.4 2.8 0.9 -1.7 -0.2 -1.3 -0.6 -0.6 -0.9 0.2 0.1 -0.3 -0.2 -0.3 -0.4 -0.2 -0.7 -0.0 -0.3 -0.6 -0.5 0.2 -0.3 -0.7 -0.9 0.0 -0.3 -0.7 0.0 -1.7 1.1 0.4 0.0 -0.1 0.6 0.4 0.2 0.6 -0.3 0.2 -0.0 1.7 0.8 0.7 -0.3 0.8 0.4 0.3 0.7 0.6
Hearing difficulty/problems: Yes 0.3 0.4 2.9 0.4 0.6 -0.8 -1.1 -0.5 -0.5 -0.8 -0.0 0.1 -0.3 0.4 0.1 0.0 -1.0 0.2 0.1 -0.3 -0.3 -0.6 0.9 0.6 -0.1 0.1 0.0 -0.4 0.1 0.8 -1.5 1.0 0.0 0.0 -0.1 0.4 0.2 0.2 0.8 -0.4 0.2 0.5 1.7 1.1 0.9 -1.0 0.6 0.3 0.4 0.7 0.7
Relative age of first facial hair 2.3 4.7 8.6 2.9 -0.2 1.9 -1.9 2.2 2.8 2.6 2.8 2.9 2.5 2.2 1.4 1.6 1.4 0.2 2.2 2.5 1.4 2.5 2.5 0.1 -0.8 1.3 0.0 2.6 1.5 2.6 -1.6 0.9 2.4 0.0 2.6 2.5 2.7 2.6 2.9 2.7 2.9 2.7 1.9 1.4 1.8 2.2 2.6 2.7 2.5 2.6 2.2
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 2.9 0.2 -0.6 0.3 -1.7 0.4 0.4 -0.0 -0.2 0.1 0.4 0.5 0.3 0.6 -0.4 0.8 1.6 0.4 -0.5 0.5 0.3 0.8 -0.3 0.4 0.0 0.2 0.1 0.9 -0.9 -0.8 0.1 0.0 -0.0 0.8 0.5 0.7 0.8 0.4 0.5 0.4 0.7 0.5 0.7 0.1 0.6 0.5 0.5 0.5 0.5
Ever used hormone-replacement therapy (HRT) 0.5 0.7 5.8 -0.9 0.1 -0.5 0.0 -0.8 -1.4 -1.7 -0.7 -0.7 -1.1 -0.4 -0.4 -0.4 -1.7 1.1 -0.4 -1.1 0.3 -0.9 -0.4 -0.3 1.2 0.3 0.0 -1.4 0.1 -0.7 -0.6 0.1 -0.6 0.0 -0.8 -0.4 -0.8 -0.6 -0.5 -1.3 -0.9 -0.3 0.3 0.9 0.3 -2.4 -0.5 -0.7 -0.4 -0.5 -0.1
Ever had hysterectomy (womb removed) 0.4 0.5 1.8 -0.6 -0.9 -0.6 -0.6 -1.0 -0.5 -0.4 -0.6 -0.5 -0.7 -0.8 -1.0 0.3 1.0 0.7 0.0 -0.7 -0.9 -1.0 -0.6 -1.2 -0.7 -0.9 0.0 -0.4 -1.3 -1.1 0.0 0.2 -0.5 0.0 -0.5 -0.5 -0.4 -0.9 -0.6 -0.6 -0.7 -0.7 -0.6 -0.6 -0.6 0.1 -0.6 -0.6 -0.7 -0.5 -0.6
Systolic blood pressure, automated reading 0.4 1.1 5.6 -0.8 -1.0 -1.0 -0.1 -1.0 -1.0 -1.0 -0.8 -0.8 -1.2 -1.1 -0.4 -1.8 -1.6 -1.8 -2.4 -1.2 -0.9 -0.9 -1.2 -0.1 -0.1 -1.3 0.0 -1.1 -0.9 -1.0 -0.4 -0.7 -0.3 0.0 -0.6 -0.9 -1.0 -1.2 -1.0 -1.0 -1.0 -1.0 -1.5 0.1 -0.6 -1.9 -1.1 -1.1 -0.6 -1.1 -0.6
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 1.5 0.2 0.8 -0.3 -0.6 0.0 -0.3 -0.5 -0.3 -0.1 -0.0 0.8 0.6 0.6 0.6 0.8 1.2 -0.0 0.1 -0.0 0.5 0.1 -0.2 0.1 0.0 0.0 0.8 0.3 -0.5 -0.2 0.2 0.0 -0.0 0.5 0.1 0.3 0.4 -0.0 0.3 0.1 1.2 0.5 0.5 -0.1 0.5 0.3 0.3 0.5 0.4
Angina 0.2 0.2 1.6 0.1 1.0 0.0 -0.6 -0.6 -0.7 -1.1 -0.0 -0.1 -0.7 0.2 0.0 0.7 -0.2 -0.0 0.0 -0.7 0.2 -0.5 0.4 0.8 0.6 -0.2 0.0 -0.6 0.3 0.0 -1.0 0.2 0.2 0.0 -0.2 0.4 -0.2 -0.0 0.1 -0.5 -0.2 0.1 1.3 0.7 0.5 -0.8 0.2 -0.1 0.0 0.2 0.2
Medication for hormone replacement therapy 0.4 0.4 1.3 -0.7 1.1 -0.1 0.6 0.0 -0.8 -0.8 -0.9 -0.5 -0.6 -0.1 0.1 0.6 -0.6 0.6 -0.8 -0.7 1.1 -0.5 -0.2 0.1 0.9 0.7 0.0 -0.7 0.2 -0.6 0.6 1.1 -0.9 0.0 -0.7 -0.8 -0.8 -0.4 -0.8 -0.9 -0.9 -0.3 0.2 -0.3 -0.2 -0.3 -0.5 -0.5 -0.7 -0.5 -0.6
Vitamin and mineral supplements 0.4 0.6 3.1 1.2 -0.8 -1.0 -1.6 0.6 0.3 0.2 0.4 0.6 0.5 0.6 1.1 -1.2 -0.5 -1.8 -0.1 0.5 -0.3 0.4 -0.3 0.5 -1.2 -0.7 0.0 0.4 0.1 0.3 -1.6 -0.0 1.0 0.0 0.6 0.8 0.7 0.6 0.6 0.4 0.6 0.6 0.9 0.8 0.9 0.3 0.8 0.7 0.6 0.8 0.8
Supplements: Zinc 0.4 0.4 1.7 -0.9 -0.5 -1.2 1.0 -0.3 -0.3 -0.3 -0.7 -0.5 -0.5 -0.6 -0.2 -1.3 -0.7 0.9 -0.9 -0.5 0.5 -0.4 -0.8 -0.6 0.3 0.1 0.0 -0.7 -0.2 -0.2 0.8 -1.0 -0.9 0.0 -0.7 -0.9 -0.8 -0.7 -0.3 -0.4 -0.5 -0.3 -0.9 -0.4 -0.6 -0.7 -0.8 -0.7 -0.4 -0.8 -0.6
Medication: Co-codamol 0.2 0.3 2.3 0.1 1.5 -0.8 -0.3 0.2 0.2 0.1 0.1 0.3 0.3 0.5 0.5 -0.6 0.1 -0.1 0.1 0.3 0.9 0.2 0.2 0.9 1.0 1.0 0.0 0.2 0.3 0.3 -0.4 0.4 -0.3 0.0 -0.5 -0.1 0.1 0.2 -0.1 0.2 0.3 0.5 0.3 1.0 1.0 -0.7 0.4 0.4 0.6 0.4 0.7
Medication: Metformin 0.1 0.2 1.7 -0.0 -0.6 -0.9 -0.4 -0.3 -0.2 -0.1 -0.3 -0.1 -0.3 0.2 -0.1 0.6 0.8 0.3 1.3 -0.3 -0.7 -0.3 0.3 0.2 -0.2 0.3 0.0 -0.2 -0.5 -0.3 0.1 1.0 -0.2 0.0 -0.4 -0.0 0.1 -0.0 -0.1 -0.1 -0.1 -0.3 0.7 -0.5 0.1 1.1 0.3 0.1 -0.3 0.2 -0.1
Diabetes (father) 0.5 0.6 5.0 -0.5 2.2 0.9 0.3 0.6 0.3 0.4 0.2 0.1 0.3 0.8 0.8 1.9 2.2 0.9 0.0 0.3 0.6 0.4 1.0 1.2 -0.1 1.3 0.0 0.7 0.7 0.0 0.8 0.3 -0.3 0.0 -0.1 -0.1 -0.1 0.2 0.1 0.4 0.1 0.0 -0.2 -0.7 -0.5 1.3 0.1 0.1 -0.1 0.1 -0.2
Diabetes (mother) 0.3 0.4 3.0 -0.3 -1.1 -1.3 0.0 0.2 -0.2 -0.4 -0.3 -0.2 -0.3 -0.4 0.2 -0.9 -1.0 1.6 -0.5 -0.3 0.7 0.1 -0.4 -0.2 1.5 0.0 0.0 -0.5 0.1 -0.5 0.0 -1.7 -0.6 0.0 -0.6 -0.4 -0.5 -0.2 -0.1 -0.3 -0.3 -0.3 -0.7 -0.2 -0.2 -0.7 -0.4 -0.4 -0.2 -0.5 -0.3
Severe depression (siblings) 0.3 0.3 0.9 -0.5 -0.3 -0.4 0.2 -0.9 -0.6 -0.6 -0.7 -0.4 -0.8 -0.8 -0.8 -0.1 0.3 0.4 -0.8 -0.8 -0.5 -0.8 -0.0 -0.9 -0.2 -0.5 0.0 -0.6 -0.5 -0.6 0.5 -0.3 -0.4 0.0 -0.6 -0.6 -0.6 -0.6 -0.2 -0.6 -0.7 -0.9 -0.7 -0.7 -0.7 -0.0 -0.7 -0.8 -0.7 -0.7 -0.7
Pack years adult smoking proportion 0.6 1.0 2.7 1.1 0.0 0.1 0.2 1.6 1.2 1.4 0.6 1.2 1.2 1.0 1.1 -0.5 0.1 -1.3 0.4 1.2 1.2 1.3 0.9 1.1 0.7 0.2 0.0 1.0 1.5 1.0 -0.0 1.4 1.1 0.0 1.4 0.9 1.3 1.1 0.9 1.0 1.0 1.1 0.8 0.6 0.9 1.1 0.9 1.1 0.8 1.0 0.8
Impedance of leg (right) 0.2 0.8 5.6 -0.4 0.4 -0.0 0.0 -1.2 -0.7 -0.7 -0.6 -0.6 -0.8 -0.2 -0.6 1.4 1.9 -1.2 1.1 -0.8 -2.0 -1.0 -0.7 0.5 -2.4 -2.0 0.0 -0.4 -0.8 -0.7 0.4 0.1 0.4 0.0 0.2 0.1 -0.1 -0.7 -0.7 -0.5 -0.7 -0.7 0.3 -1.3 -0.8 1.6 -0.6 -0.6 -1.0 -0.5 -0.9
Leg fat-free mass (left) 0.8 4.2 15.1 -1.9 -3.9 -1.6 0.2 -1.6 -2.0 -2.1 -1.5 -1.6 -1.9 -2.3 -1.4 -3.7 -3.9 -1.6 -1.9 -1.9 -2.0 -1.6 -1.8 -2.5 0.8 -1.4 0.0 -2.5 -1.7 -2.0 -0.3 -1.6 -2.7 0.0 -2.8 -2.5 -2.4 -1.8 -1.9 -2.1 -2.1 -2.0 -2.0 -0.9 -1.7 -2.8 -1.9 -2.0 -1.7 -2.0 -1.6
Trunk fat percentage 0.4 1.4 6.7 -0.4 -1.9 -1.3 -2.4 -1.1 -1.9 -2.6 -0.7 -0.9 -1.4 0.3 0.6 0.1 -1.8 -0.3 0.9 -1.4 -2.4 -1.4 -0.1 0.5 -1.7 -0.1 0.0 -1.6 -1.2 -0.5 -2.4 -0.2 -0.7 0.0 -1.6 0.0 -0.9 -0.6 -0.3 -1.6 -0.9 -0.9 2.0 0.7 0.5 -1.2 0.2 -0.3 -0.5 0.1 0.1
Hand grip strength (right) 0.2 0.5 3.4 -0.1 -0.2 0.4 0.3 -0.6 0.2 0.2 0.5 0.5 0.1 -0.9 -1.1 -1.4 -0.7 -1.9 -1.6 0.1 -0.3 0.1 -0.3 -1.3 0.5 -1.2 0.0 0.1 -0.2 -0.4 -0.4 -1.4 -0.7 0.0 -0.5 -0.8 -0.4 -0.2 -0.4 0.1 -0.3 0.0 -1.6 0.3 -0.1 -1.1 -0.5 -0.3 0.0 -0.5 -0.1
Townsend deprivation index at recruitment 0.6 0.8 4.2 -0.7 -1.7 -1.4 -0.6 -0.3 -1.2 -1.4 -0.7 -0.8 -1.0 0.5 1.6 -1.1 -1.1 0.0 0.6 -1.0 -2.0 -1.0 -0.7 0.2 -2.0 0.4 0.0 -1.2 -0.7 -0.9 -1.0 -0.3 -0.4 0.0 -1.1 -0.2 -0.7 -0.7 -0.8 -0.9 -0.6 -1.0 0.8 -0.2 -0.2 -0.3 -0.1 -0.3 -0.6 -0.1 -0.3
Current tobacco smoking 0.9 1.5 3.2 1.4 0.6 1.7 -0.3 1.4 1.5 1.4 1.2 1.2 1.6 0.8 0.5 0.8 1.6 -0.2 0.8 1.6 1.8 1.4 1.0 -0.1 0.6 0.9 0.0 1.7 1.6 1.4 -0.4 0.7 1.3 0.0 1.5 1.3 1.6 1.4 1.4 1.5 1.3 1.2 0.5 1.3 1.4 0.2 1.4 1.5 1.4 1.3 1.5
Average weekly fortified wine intake 0.4 0.5 2.0 0.7 -0.0 0.2 -0.9 -0.4 0.5 0.4 0.2 0.5 0.6 0.1 -0.6 0.0 0.7 -0.7 1.1 0.6 -0.4 0.2 -0.3 0.0 -1.4 -1.1 0.0 0.6 -0.5 0.6 -0.9 0.4 0.8 0.0 1.0 0.7 1.1 0.5 0.4 0.6 0.7 1.1 0.9 0.8 1.0 -0.2 0.7 0.7 0.8 0.7 0.7
Maternal smoking around birth 0.9 1.4 7.8 -0.1 -2.8 -1.1 -2.4 -1.0 -1.5 -2.2 -0.5 -0.4 -1.0 0.1 0.7 -0.1 -0.5 0.1 1.0 -1.0 -2.4 -1.4 -0.8 -0.7 -2.7 -2.0 0.0 -1.1 -0.8 -1.3 -2.3 -0.8 0.0 0.0 -0.7 0.5 -0.2 -0.5 0.0 -1.1 -0.6 -0.7 2.0 0.4 0.4 -0.4 0.4 -0.1 -0.5 0.3 0.1
Fed-up feelings 0.2 0.3 2.8 0.7 -0.1 -0.0 0.5 0.3 0.1 0.2 0.3 0.5 0.1 0.2 -0.2 0.6 -0.1 1.7 0.5 0.1 0.1 0.2 0.2 0.3 -0.0 0.4 0.0 0.0 -0.3 0.2 0.9 1.5 0.8 0.0 0.8 0.5 0.5 0.4 -0.2 0.2 0.2 -0.3 0.9 -0.6 -0.1 1.6 0.4 0.3 -0.2 0.3 -0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.5 5.1 0.4 -1.9 0.3 -1.2 -0.2 -1.1 -1.6 -0.2 -0.3 -0.5 0.0 0.4 0.5 -0.3 0.0 0.5 -0.5 -0.4 -0.4 0.1 -0.1 -0.4 0.1 0.0 -0.6 -0.5 -0.1 -1.6 0.8 0.2 0.0 -0.4 0.7 0.1 0.3 0.6 -0.8 -0.1 -0.2 2.3 1.0 0.7 -0.7 0.8 0.3 0.1 0.7 0.6
Relative age voice broke 0.2 0.3 3.4 0.5 -0.5 0.3 0.3 -0.3 -0.0 0.3 0.2 -0.0 -0.2 -0.5 -1.2 -0.1 0.0 1.9 0.8 -0.2 0.3 -0.0 -0.4 -1.0 -0.7 -0.2 0.0 -0.2 -1.3 -0.1 0.5 1.4 0.4 0.0 0.8 0.2 0.4 -0.1 -0.1 -0.0 0.2 -0.2 0.6 -0.5 -0.4 0.9 0.1 -0.0 -0.2 0.0 -0.2
Taking other prescription medications 1.6 2.5 9.7 1.5 0.3 0.2 -0.5 2.1 1.1 1.1 1.1 1.5 1.3 2.1 2.0 2.7 1.4 2.8 1.9 1.3 1.1 1.3 1.5 0.8 -1.0 2.3 0.0 1.4 0.5 0.9 0.4 2.8 1.4 0.0 1.6 1.8 1.7 1.7 1.4 1.1 1.4 1.1 2.8 0.2 1.1 3.1 1.9 1.8 0.9 1.9 1.2
Age when periods started (menarche) 0.1 0.3 3.5 -0.1 -0.8 0.2 -0.6 0.1 0.5 0.4 -0.0 0.1 0.0 0.3 0.7 -0.7 -0.7 -1.9 -0.1 0.0 -0.8 0.5 0.2 -0.4 -0.9 -0.4 0.0 0.2 0.4 0.3 -0.6 -1.4 0.2 0.0 0.0 0.1 0.1 0.1 0.6 0.6 0.3 0.3 -0.7 0.1 0.2 -0.1 0.1 0.1 0.4 0.1 0.2
Bilateral oophorectomy (both ovaries removed) 0.3 0.4 2.5 0.0 0.9 -0.2 -1.6 -0.7 -0.5 -0.9 -0.5 -0.5 -0.3 0.5 0.4 1.1 0.9 -0.7 0.4 -0.3 -0.3 -0.7 -0.1 0.5 -1.1 -0.2 0.0 -0.1 0.1 0.3 -1.5 0.3 0.3 0.0 -0.1 0.4 -0.1 -0.4 -0.0 -0.4 0.0 0.2 0.8 1.2 0.7 -1.2 0.2 0.1 0.4 0.2 0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 1.8 -0.7 0.4 0.1 0.6 -0.7 0.0 0.1 -0.6 -0.6 0.0 -0.7 -1.3 -1.0 -0.3 0.0 -0.0 0.0 0.1 -0.5 -0.4 -0.2 0.7 -0.2 0.0 -0.2 -0.7 -0.2 0.7 -0.2 -0.9 0.0 -0.5 -0.7 -0.3 -0.5 -0.5 -0.3 -0.5 -0.3 -0.7 -0.3 -0.4 -0.4 -0.6 -0.3 -0.4 -0.5 -0.4
Tinnitus: Yes, but not now, but have in the past 5.8 6.2 12.8 -3.0 -1.5 -3.6 2.4 -2.2 -2.5 -2.0 -2.6 -2.4 -2.4 -2.4 -1.3 -2.9 -2.0 -0.6 -3.2 -2.4 -2.4 -2.8 -2.9 -0.3 0.0 -1.1 0.0 -2.6 -3.3 -2.7 2.1 -0.1 -3.4 0.0 -3.2 -3.4 -3.0 -2.8 -3.1 -2.8 -2.8 -2.9 -2.2 -2.7 -3.2 -0.9 -2.8 -2.7 -2.9 -2.8 -2.9
Qualifications: CSEs or equivalent 1.7 2.2 6.1 -1.8 -0.5 -2.5 1.1 -1.1 -1.2 -1.0 -1.6 -1.5 -1.4 -1.5 -0.6 -1.2 -1.2 1.6 -1.1 -1.4 -0.8 -1.6 -1.7 -0.2 -0.1 -0.5 0.0 -1.5 -1.5 -1.8 1.7 -0.6 -1.9 0.0 -1.6 -1.8 -1.7 -1.7 -2.0 -1.5 -1.8 -1.9 -1.9 -2.0 -1.8 0.2 -1.8 -1.7 -1.9 -1.9 -2.0
Serious illness, injury or assault to yourself 1.1 1.3 4.4 -1.4 -0.4 -2.0 0.1 -1.2 -1.1 -1.2 -1.7 -1.3 -1.1 -0.9 -0.7 -1.0 -2.1 0.8 -1.6 -1.1 -1.2 -1.2 -1.2 0.2 -0.4 -1.1 0.0 -1.2 -1.3 -0.8 0.3 -1.5 -1.4 0.0 -1.5 -1.3 -1.3 -1.2 -1.0 -1.1 -1.1 -1.2 -0.8 -0.7 -0.9 -0.8 -1.2 -1.2 -1.0 -1.2 -1.0
High blood pressure 0.4 1.1 7.9 0.3 1.7 -0.2 0.2 1.1 0.5 0.6 0.4 0.7 0.5 1.6 1.3 1.9 1.5 1.4 1.4 0.5 0.9 0.7 1.2 2.8 0.9 2.2 0.0 0.6 1.1 1.0 0.5 0.9 0.7 0.0 0.8 1.0 0.8 0.9 0.9 0.6 0.7 0.6 1.4 0.1 0.5 1.5 0.9 0.8 0.5 0.9 0.5
Hayfever, allergic rhinitis or eczema 0.7 1.5 5.1 1.7 -1.8 1.2 -1.3 1.0 1.4 1.5 1.5 1.6 1.4 0.4 -0.8 0.2 0.6 0.7 1.7 1.4 -0.2 1.5 0.9 -1.6 -0.2 -0.1 0.0 1.2 0.1 1.0 -0.6 0.4 1.3 0.0 1.5 1.4 1.8 1.6 1.9 1.4 1.4 0.9 1.0 0.1 0.8 2.3 1.5 1.5 1.0 1.4 1.0
Multivitamins +/- minerals 0.1 0.2 1.0 -0.7 0.4 0.4 1.0 -0.1 0.0 0.2 -0.1 -0.2 -0.2 -0.2 -0.1 -0.2 -0.2 0.4 -0.5 -0.2 -0.0 -0.2 -0.0 -0.4 0.6 0.8 0.0 -0.2 -0.2 0.1 0.9 0.7 -0.8 0.0 -0.5 -0.7 -0.5 -0.4 -0.5 -0.2 -0.2 -0.1 -0.5 -0.2 -0.5 -0.7 -0.3 -0.3 -0.1 -0.4 -0.3
Stomach or abdominal pain in last month 0.3 0.4 2.0 0.6 -1.3 0.2 -0.2 -0.0 0.7 0.8 0.5 0.4 0.8 -0.4 -1.2 -0.8 -0.2 -0.2 0.1 0.8 0.1 0.5 -0.5 -1.4 0.5 -0.5 0.0 0.7 -0.4 0.5 -0.3 -0.4 0.5 0.0 0.7 0.5 0.9 0.6 0.6 0.6 0.6 0.7 -0.1 0.8 0.6 -0.6 0.5 0.6 0.8 0.5 0.7
Supplements: Glucosamine 0.2 0.2 1.3 -0.1 0.5 0.6 0.8 0.7 0.7 0.9 0.7 0.3 0.5 0.1 0.1 -0.1 0.3 0.3 0.6 0.5 1.0 0.9 0.4 -1.1 0.1 0.3 0.0 0.5 0.6 0.2 0.5 -0.1 0.0 0.0 0.3 0.0 0.4 0.4 0.5 0.7 0.5 0.3 -0.9 0.0 -0.0 -0.2 0.1 0.2 0.5 0.1 0.2
Diverticular disease/diverticulitis (self-reported) 1.9 2.3 4.7 2.1 -0.7 1.2 -1.1 1.7 1.7 1.4 1.5 1.8 2.1 1.1 0.5 -0.1 0.2 -0.3 0.6 2.1 1.6 1.9 1.1 -1.5 0.0 0.7 0.0 1.7 1.3 1.5 -1.6 0.2 1.7 0.0 1.6 1.7 2.0 1.9 2.0 1.6 1.8 1.8 1.2 2.2 2.1 -0.2 1.9 2.0 2.0 1.9 2.1
Medication: Atenolol 0.4 0.5 1.6 0.5 0.3 0.2 -1.3 0.3 0.5 0.1 0.6 0.5 0.4 1.0 1.0 1.0 0.5 0.6 0.8 0.4 0.1 0.3 0.9 0.8 -1.0 0.8 0.0 0.5 0.6 1.0 -1.2 -0.7 0.5 0.0 0.5 0.8 0.6 0.4 1.0 0.5 0.8 0.8 0.8 1.1 0.9 -0.4 0.7 0.7 0.9 0.8 0.9
Medication: Levothyroxine sodium 0.8 1.3 4.1 -0.9 -1.1 -0.6 0.6 -1.8 -1.1 -1.0 -0.8 -1.1 -1.2 -1.6 -2.0 -1.3 -1.1 -1.0 -0.7 -1.2 -1.4 -1.3 -1.6 0.7 1.6 -2.0 0.0 -1.3 -0.8 -0.9 0.4 -0.9 -0.9 0.0 -0.7 -0.9 -0.9 -1.2 -1.3 -1.1 -1.1 -1.1 -1.1 -0.9 -1.0 -0.9 -1.3 -1.3 -1.0 -1.3 -1.1
Sitting height 0.6 4.2 14.3 -2.0 -2.7 -1.2 1.1 -1.7 -1.8 -1.7 -1.6 -1.6 -1.9 -2.3 -1.0 -3.8 -3.0 -3.3 -1.8 -1.9 -1.9 -1.6 -1.8 -2.4 0.2 -2.4 0.0 -2.3 -1.2 -2.0 0.3 -1.6 -2.5 0.0 -2.6 -2.6 -2.5 -2.1 -2.1 -1.9 -2.2 -2.0 -2.9 -1.0 -1.9 -2.8 -2.2 -2.2 -1.7 -2.2 -1.7
Chronic bronchitis/emphysema (father) 0.9 1.0 3.5 1.2 1.3 1.1 -1.0 0.6 1.0 1.1 1.1 1.3 0.9 0.9 0.3 1.4 1.9 -0.8 0.2 0.9 1.1 1.1 0.9 -0.3 -0.5 0.3 0.0 1.2 0.6 1.1 -1.1 0.9 1.2 0.0 1.1 1.1 1.2 1.0 1.1 1.1 1.2 1.3 0.6 1.3 1.1 -0.3 1.1 1.0 1.3 1.1 1.3
High blood pressure (mother) 0.7 1.0 6.4 -1.2 0.7 -1.3 1.9 0.3 0.1 0.4 -0.8 -0.5 -0.3 -0.6 0.2 -0.9 -0.2 0.3 -2.2 -0.3 1.5 0.1 -0.1 1.3 2.5 0.6 0.0 -0.2 0.3 -0.3 1.7 -0.5 -1.5 0.0 -1.1 -1.6 -1.0 -0.6 -0.5 -0.1 -0.4 -0.5 -2.2 -0.7 -1.2 -0.5 -1.2 -0.9 -0.4 -1.1 -0.8
Body mass index (BMI) 0.1 0.5 5.2 0.1 -2.0 -0.2 -1.5 0.0 -0.5 -0.9 0.0 0.0 -0.3 0.2 0.2 -0.9 -2.3 0.7 -0.0 -0.3 -0.6 -0.1 0.4 -0.9 -0.4 0.7 0.0 -0.7 -0.2 0.1 -1.6 -0.7 -0.2 0.0 -0.5 0.1 -0.3 0.1 0.3 -0.5 -0.1 -0.2 0.8 0.8 0.6 -1.0 0.4 0.2 0.1 0.3 0.4
Impedance of leg (left) 0.2 0.9 3.4 -0.7 1.0 -0.2 0.3 -1.5 -0.9 -0.9 -0.6 -0.9 -1.1 -0.3 -0.5 1.5 1.8 -0.6 0.7 -1.1 -1.6 -1.2 -0.8 1.0 -1.8 -1.6 0.0 -0.5 -0.9 -0.9 0.6 -0.3 -0.1 0.0 -0.4 -0.3 -0.5 -1.0 -1.0 -0.7 -0.9 -0.9 -0.2 -1.3 -0.9 1.2 -0.8 -0.8 -1.1 -0.8 -1.1
Leg predicted mass (left) 0.8 4.4 15.3 -2.0 -3.9 -1.7 0.2 -1.7 -2.1 -2.2 -1.6 -1.6 -1.9 -2.4 -1.5 -3.8 -3.9 -1.6 -2.0 -1.9 -2.1 -1.7 -1.8 -2.5 0.8 -1.4 0.0 -2.5 -1.8 -2.1 -0.3 -1.7 -2.8 0.0 -2.9 -2.6 -2.5 -1.9 -1.9 -2.2 -2.2 -2.1 -2.1 -1.0 -1.7 -2.9 -2.0 -2.1 -1.8 -2.1 -1.7
Trunk fat mass 0.4 1.9 6.8 -1.0 -2.6 -1.6 -1.5 -1.4 -2.1 -2.6 -1.0 -1.3 -1.7 -0.6 -0.1 -1.0 -2.4 -0.6 0.1 -1.7 -2.4 -1.6 -0.7 -0.4 -1.1 -0.5 0.0 -2.1 -1.6 -1.1 -1.6 -0.6 -1.5 0.0 -2.2 -0.9 -1.6 -1.1 -1.0 -1.9 -1.4 -1.5 0.7 -0.0 -0.4 -1.6 -0.6 -1.0 -1.1 -0.7 -0.6
Waist circumference 0.2 0.8 6.5 -0.3 -2.5 -0.7 -1.4 -0.5 -1.0 -1.2 -0.3 -0.5 -0.7 -0.5 -0.4 -1.3 -2.1 0.2 -0.4 -0.7 -1.2 -0.6 -0.2 -1.2 -0.5 0.1 0.0 -1.1 -1.2 -0.5 -1.3 -0.8 -1.0 0.0 -1.5 -0.6 -0.8 -0.4 -0.2 -0.9 -0.6 -0.8 0.2 0.2 -0.1 -1.1 -0.1 -0.4 -0.4 -0.2 -0.1
Number of incorrect matches in round 0.6 1.0 6.3 -1.0 -0.4 -0.9 0.0 -1.6 -1.0 -1.1 -0.8 -0.9 -0.9 -1.5 -1.9 -1.4 -1.4 -0.1 -2.5 -0.9 -0.4 -1.3 -0.8 -0.8 0.6 -1.3 0.0 -1.0 -1.1 -1.1 -0.2 -1.0 -0.8 0.0 -0.7 -0.9 -0.8 -0.8 -0.7 -1.1 -1.1 -0.6 -1.0 -0.1 -0.4 -1.8 -1.0 -1.0 -0.7 -1.0 -0.7
Past tobacco smoking 0.2 0.4 2.3 -0.5 1.5 -0.6 0.8 -0.2 0.2 0.3 -0.9 -0.6 -0.0 -0.4 -0.0 0.1 1.5 -0.6 -1.3 -0.0 0.7 -0.1 -0.5 1.0 0.6 -0.6 0.0 0.3 0.4 -0.1 0.9 -1.0 -0.0 0.0 0.0 -0.6 -0.4 -0.8 -0.3 -0.0 -0.1 -0.2 -1.3 -0.2 -0.5 -0.5 -0.7 -0.5 -0.1 -0.7 -0.4
Alcohol usually taken with meals 2.1 3.5 8.2 2.2 1.1 2.1 -0.8 1.3 2.9 2.7 2.1 2.7 2.4 1.0 -0.8 1.2 1.9 -0.6 0.9 2.3 1.9 2.5 2.1 -0.3 1.7 -0.0 0.0 2.6 2.0 2.5 -0.8 -0.9 1.9 0.0 2.3 1.8 2.4 2.2 2.5 2.7 2.3 2.3 -0.2 1.8 1.9 0.1 1.7 1.9 2.4 1.6 2.0
Nervous feelings 0.7 1.2 5.5 0.9 1.2 0.4 -0.8 0.6 0.6 0.3 1.3 0.6 0.8 1.1 1.2 1.7 1.6 -2.4 0.2 0.8 0.9 0.7 1.4 2.2 1.2 1.1 0.0 1.2 1.1 1.2 -1.7 0.5 0.4 0.0 0.1 0.9 0.7 1.0 1.5 0.8 1.0 1.2 1.0 1.7 1.4 -0.8 1.0 1.0 1.3 1.1 1.3
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 3.5 0.3 -0.8 -0.9 -0.9 -0.7 -1.0 -1.4 -1.0 -0.5 -0.7 -0.5 -0.2 -0.2 -0.5 -0.4 -1.0 -0.7 0.4 -0.8 -0.2 0.0 0.1 0.2 0.0 -0.7 -0.7 0.3 -1.6 1.3 -0.7 0.0 -1.0 -0.2 -0.4 -0.2 0.3 -0.9 -0.3 -0.1 1.2 1.2 0.4 -1.9 0.2 -0.1 0.1 0.2 0.4
Hearing difficulty/problems with background noise 1.2 1.9 9.7 1.9 0.7 0.2 -2.1 -0.0 0.1 -0.4 1.2 1.0 0.6 0.8 -0.1 1.2 -0.1 0.8 0.5 0.6 1.1 0.2 1.4 0.6 0.7 0.3 0.0 0.6 0.4 1.5 -2.7 1.5 1.4 0.0 1.0 1.9 1.4 1.4 2.0 0.3 1.2 1.6 3.1 2.6 2.3 -1.6 1.9 1.5 1.6 1.9 2.1
Hair/balding pattern: Pattern 2 0.2 0.3 1.0 0.5 0.2 0.1 -0.4 0.3 0.6 0.7 0.8 0.8 0.6 0.4 -0.1 -0.7 -0.5 -0.3 0.5 0.6 0.1 0.5 0.2 0.4 -0.1 0.4 0.0 0.5 0.1 0.4 -0.5 0.6 0.6 0.0 0.7 0.6 0.8 0.3 0.2 0.6 0.5 0.4 0.1 0.9 1.0 0.0 0.6 0.6 0.6 0.6 0.8
Had menopause 2.4 3.0 7.1 1.7 1.7 0.6 -1.5 1.8 1.3 1.0 2.0 1.8 1.7 2.6 2.6 1.5 1.1 1.1 1.5 1.7 1.3 1.3 1.9 2.2 -1.1 2.1 0.0 1.6 1.6 1.8 -1.7 1.6 1.7 0.0 1.5 2.1 1.8 1.9 1.7 1.5 2.0 2.0 2.7 2.0 2.0 0.8 2.2 2.1 1.9 2.3 2.1
Had other major operations 0.2 0.2 1.5 -0.4 -0.3 -0.6 0.4 -0.2 -0.3 -0.5 -0.4 -0.3 -0.4 -0.0 0.3 -0.9 -0.9 1.2 -1.2 -0.4 -0.1 -0.4 0.2 -0.9 -0.3 0.2 0.0 -0.6 -0.3 -0.2 0.1 -0.6 -0.4 0.0 -0.5 -0.4 -0.6 -0.3 -0.0 -0.4 -0.2 -0.2 0.1 -0.0 -0.3 -0.5 -0.1 -0.2 -0.2 -0.2 -0.2
Forced vital capacity (FVC) 0.1 0.2 1.3 0.2 -0.4 0.1 1.1 0.6 0.4 0.6 0.3 0.6 0.3 -0.4 0.3 -0.5 -0.0 -1.0 0.1 0.3 0.6 0.5 0.1 -1.2 0.7 -0.5 0.0 0.3 0.5 -0.4 0.8 0.2 -0.0 0.0 -0.0 -0.3 -0.1 0.1 -0.2 0.3 -0.0 -0.1 -1.0 -0.5 -0.4 0.4 -0.3 -0.1 -0.1 -0.2 -0.3
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.2 1.5 -0.3 -0.8 0.4 -0.1 -0.6 -0.0 -0.2 -0.4 -0.4 0.0 -0.4 -1.0 -1.0 -0.8 -0.3 0.2 0.0 -0.8 -0.3 -0.2 -1.2 -0.5 -0.9 0.0 -0.2 -0.6 -0.2 -0.3 -1.0 -0.5 0.0 -0.4 -0.3 -0.1 -0.3 0.2 -0.2 -0.3 -0.1 -0.0 -0.3 -0.2 0.1 -0.1 -0.0 -0.3 -0.1 -0.2
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 2.2 -0.8 0.3 -1.2 0.3 -0.9 -0.7 -0.7 -0.5 -0.6 -0.9 -0.6 -0.2 0.5 0.0 0.2 -1.2 -0.9 -0.4 -0.7 -0.3 1.2 0.6 0.5 0.0 -0.6 -1.1 -0.2 0.3 0.5 -1.3 0.0 -1.5 -1.0 -0.9 -0.6 -0.5 -0.6 -0.4 -0.4 0.0 -0.6 -0.8 -0.1 -0.5 -0.6 -0.5 -0.6 -0.6
Qualifications: None of the above 0.7 1.6 4.5 -1.2 -0.6 -0.6 0.4 -1.5 -2.0 -1.8 -1.3 -1.8 -1.8 -1.0 -0.9 -0.5 -1.1 2.1 -0.8 -1.8 -1.4 -1.9 -1.3 0.1 -0.8 -0.1 0.0 -1.9 -1.5 -1.4 0.7 0.3 -0.7 0.0 -0.9 -0.7 -1.2 -1.5 -1.5 -1.8 -1.5 -1.7 0.5 -1.4 -1.2 -0.1 -1.1 -1.3 -1.6 -1.1 -1.4
Financial difficulties in last 2 years 2.2 3.0 8.6 -1.2 -1.1 -2.2 -1.1 -2.6 -2.7 -2.9 -2.0 -1.9 -2.5 -1.6 -1.3 -1.8 -2.2 -0.1 -1.6 -2.5 -1.5 -2.7 -1.8 -0.3 -0.4 -1.8 0.0 -2.6 -2.4 -1.8 -1.2 0.8 -1.5 0.0 -1.9 -1.2 -1.7 -2.0 -1.8 -2.4 -1.8 -1.7 0.5 0.3 -0.5 -2.8 -1.0 -1.5 -1.2 -1.0 -0.8
Mouth/teeth dental problems 0.5 0.8 4.2 -0.7 -0.1 -0.2 1.4 0.1 -0.4 0.0 -0.5 -0.4 -0.5 -0.3 0.8 0.5 1.8 -0.8 0.6 -0.5 -0.7 -0.6 -0.4 -1.4 -0.9 0.1 0.0 -0.2 -0.4 -1.2 2.0 1.4 -0.7 0.0 -0.8 -0.9 -1.0 -0.8 -0.7 -0.4 -0.7 -0.9 -0.5 -1.7 -1.5 1.6 -0.7 -0.7 -1.1 -0.7 -1.2
Heart attack 0.7 0.9 10.0 0.5 2.2 1.4 -0.2 0.1 -0.5 -0.9 0.2 0.0 -0.4 0.8 0.3 3.2 0.6 2.4 0.9 -0.4 1.0 0.2 1.0 1.2 0.8 1.7 0.0 -0.2 1.1 0.6 0.0 0.4 1.0 0.0 0.9 1.1 0.2 0.6 0.4 -0.2 0.1 0.1 1.5 0.6 0.9 -0.0 0.5 0.2 0.2 0.5 0.4
Allergy 0.8 1.8 4.5 -1.9 1.0 -1.2 1.1 -1.2 -1.8 -1.9 -1.4 -1.7 -1.7 -0.6 0.7 0.0 -0.1 -0.7 -1.2 -1.7 -0.5 -1.6 -0.7 1.2 0.3 -0.0 0.0 -1.5 -0.3 -1.4 0.5 -1.0 -1.5 0.0 -1.8 -1.6 -2.0 -1.7 -1.8 -1.7 -1.7 -1.3 -1.2 -0.6 -1.2 -2.1 -1.7 -1.7 -1.4 -1.6 -1.3
Pain all over the body in last month 0.9 0.9 3.6 -1.4 0.5 -1.1 1.5 -0.7 -0.5 -0.5 -0.9 -0.8 -0.7 -0.7 -0.3 -0.2 -0.2 0.5 -1.9 -0.7 0.4 -0.7 -1.1 1.2 1.4 -0.4 0.0 -0.6 0.1 -0.7 1.6 -1.5 -0.9 0.0 -0.7 -1.1 -1.1 -0.9 -1.1 -0.6 -0.9 -0.9 -1.7 -1.0 -1.2 -0.6 -1.3 -1.1 -0.9 -1.3 -1.1
Diabetes (self-reported) 0.4 0.5 2.5 -0.5 1.0 -1.2 -0.5 -0.4 -1.2 -1.2 -0.9 -0.9 -0.7 0.3 0.4 0.9 0.9 0.5 0.8 -0.7 -0.3 -0.9 0.1 1.5 0.1 1.2 0.0 -0.7 -0.5 -0.4 0.0 1.6 -0.8 0.0 -0.9 -0.2 -0.5 -0.4 -0.7 -1.0 -0.6 -0.7 1.4 -0.2 -0.0 0.1 0.1 -0.2 -0.6 0.0 -0.3
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 2.8 0.4 -0.9 0.6 -0.2 0.6 0.8 0.8 0.4 0.6 0.7 0.1 -0.2 -1.3 -0.5 0.1 -0.1 0.7 -0.4 0.8 0.6 -1.7 -0.8 -0.2 0.0 0.5 0.1 0.1 -0.1 -1.1 -0.0 0.0 0.1 0.1 0.6 0.6 0.8 0.7 0.5 0.3 -0.0 -0.5 0.0 1.7 0.4 0.5 0.1 0.4 0.0
Medication: Ramipril 1.5 1.9 9.1 1.6 0.4 0.0 -1.9 0.8 0.7 0.5 1.2 1.0 0.8 1.7 1.4 2.0 2.2 0.2 2.2 0.8 -0.1 0.5 1.5 1.9 -0.9 0.9 0.0 1.0 0.3 1.2 -1.3 1.8 1.4 0.0 1.1 1.8 1.5 1.3 1.6 0.9 1.4 1.4 3.0 0.8 1.4 1.7 1.9 1.7 1.1 1.9 1.3
Medication: Simvastatin 0.8 1.2 9.1 0.5 0.0 0.0 -0.6 1.4 0.2 0.4 0.5 0.4 0.3 1.4 1.9 2.3 2.2 1.5 2.7 0.3 -0.4 0.6 1.1 0.5 -1.5 1.4 0.0 0.5 0.2 0.1 0.8 2.0 0.9 0.0 0.7 1.0 0.6 0.7 0.4 0.3 0.5 0.0 1.8 -1.0 -0.1 3.0 1.0 0.7 -0.2 0.9 -0.0
Fluid intelligence score 0.1 0.2 2.4 -0.1 -0.1 -1.0 0.1 0.7 0.3 0.2 -0.0 0.2 0.1 0.5 1.5 -0.4 -0.2 -1.1 0.6 0.1 0.0 0.3 0.4 0.9 0.1 0.6 0.0 0.0 0.6 0.2 0.1 0.1 -0.4 0.0 -0.4 -0.2 -0.2 -0.0 0.1 0.2 0.2 0.2 -0.0 0.0 -0.1 0.3 -0.0 0.0 0.1 0.1 0.0
Illnesses of siblings 0.3 0.4 2.8 -0.2 -0.8 -0.2 -0.0 -0.5 -0.7 -0.7 -0.2 -0.5 -0.4 -1.1 -0.6 -0.7 -0.2 -0.5 0.3 -0.4 -0.3 -0.8 -1.4 -1.7 -0.9 -1.0 0.0 -0.5 -1.4 -1.2 -0.1 0.3 -0.3 0.0 -0.2 -0.3 -0.2 -0.5 -0.7 -0.7 -0.6 -0.6 0.2 -0.3 -0.3 -0.4 -0.4 -0.4 -0.6 -0.3 -0.4
Neuroticism score 0.2 0.3 1.0 0.8 -0.6 -0.2 -0.5 -0.1 0.2 -0.0 0.5 0.8 0.3 0.1 -0.5 0.8 0.2 0.2 -0.0 0.3 0.7 0.2 0.6 0.5 0.6 -0.3 0.0 0.4 0.1 0.7 -0.8 0.6 0.7 0.0 0.6 0.9 0.8 0.8 0.8 0.3 0.5 0.5 1.0 1.0 0.8 -0.3 0.7 0.6 0.7 0.7 0.8
Weight 0.4 2.1 11.8 -1.1 -3.4 -1.2 -0.7 -1.3 -1.6 -1.8 -0.8 -1.0 -1.4 -1.4 -1.0 -2.5 -3.1 -0.9 -0.9 -1.4 -1.8 -1.2 -0.9 -2.0 -0.1 -1.0 0.0 -1.9 -1.4 -1.3 -1.0 -1.4 -1.8 0.0 -2.1 -1.5 -1.6 -1.1 -1.0 -1.5 -1.4 -1.4 -0.9 -0.3 -0.8 -2.0 -1.0 -1.2 -1.1 -1.1 -0.8
Impedance of arm (right) 0.3 1.3 5.1 0.0 0.5 -1.5 -1.5 -1.3 -1.6 -1.9 -0.8 -0.7 -1.1 0.0 0.6 1.7 1.5 -1.4 1.3 -1.1 -2.2 -1.8 -0.3 1.5 -2.2 -1.0 0.0 -0.8 -1.4 -0.7 -1.2 2.0 -0.1 0.0 -0.8 0.2 -0.4 -0.7 -0.4 -1.2 -0.7 -0.7 2.3 -0.5 -0.2 0.7 0.2 -0.2 -0.9 0.1 -0.4
Arm fat percentage (right) 0.2 0.9 5.0 0.1 -1.8 -0.8 -2.2 -0.7 -1.4 -1.9 -0.4 -0.4 -0.9 0.1 0.3 0.0 -1.6 0.2 0.3 -0.9 -1.6 -1.1 0.1 -0.6 -1.6 0.1 0.0 -1.2 -1.1 -0.3 -2.1 0.4 -0.3 0.0 -1.0 0.1 -0.5 -0.3 -0.0 -1.2 -0.6 -0.6 1.9 0.6 0.5 -1.0 0.4 -0.1 -0.3 0.3 0.2
Trunk fat-free mass 0.8 4.5 17.2 -1.8 -3.8 -0.7 1.8 -1.4 -1.0 -0.8 -1.1 -1.1 -1.3 -2.9 -2.4 -4.1 -3.4 -1.6 -2.6 -1.3 -1.1 -0.9 -1.9 -4.2 1.2 -2.2 0.0 -1.8 -1.5 -2.1 1.1 -2.6 -2.6 0.0 -2.2 -2.8 -2.1 -1.7 -1.8 -1.3 -1.9 -1.8 -4.0 -1.5 -2.2 -2.4 -2.4 -2.1 -1.6 -2.4 -1.9
Hip circumference 0.5 2.2 12.1 -1.1 -2.9 -1.3 -0.6 -1.4 -1.7 -2.0 -1.0 -1.1 -1.6 -1.2 -0.7 -2.4 -3.5 -0.9 -0.9 -1.6 -2.3 -1.4 -1.0 -1.7 -0.6 -1.1 0.0 -2.1 -1.5 -1.4 -0.9 -1.1 -1.6 0.0 -2.0 -1.4 -1.7 -1.2 -1.2 -1.7 -1.5 -1.6 -0.6 -0.6 -0.9 -1.6 -1.1 -1.3 -1.2 -1.2 -1.0
Time employed in main current job 1.3 1.5 7.2 0.8 1.2 0.7 -0.2 1.8 1.7 1.9 1.2 0.9 1.7 1.4 1.1 0.6 1.2 1.6 0.4 1.7 2.1 1.6 0.8 1.1 0.7 2.7 0.0 1.7 0.7 1.3 0.2 0.5 0.5 0.0 0.7 0.9 1.3 1.3 1.1 1.5 1.5 1.4 0.5 0.8 1.0 1.0 1.2 1.4 1.4 1.2 1.2
Alcohol intake versus 10 years previously 0.9 1.3 8.0 0.9 0.9 0.3 -1.2 1.8 0.9 0.6 0.2 0.7 0.9 2.0 2.8 0.3 -0.8 -0.8 0.4 0.9 0.7 1.1 0.5 1.0 -1.1 1.4 0.0 0.9 1.7 1.0 -1.1 0.7 1.1 0.0 0.8 1.4 0.9 0.9 1.1 1.0 1.2 1.3 1.5 1.7 1.5 -0.1 1.5 1.3 1.4 1.4 1.5
Father’s age at death 0.8 1.1 4.8 -0.5 -1.5 -0.0 0.9 -1.4 -0.6 -0.2 -0.5 -0.7 -0.7 -1.5 -2.2 -1.5 -0.6 -0.2 -0.0 -0.7 -1.4 -1.1 -1.4 -2.1 -0.1 -1.8 0.0 -0.9 -1.7 -1.1 0.7 0.3 -0.6 0.0 -0.4 -0.9 -0.6 -1.1 -1.4 -0.7 -0.9 -1.0 -1.1 -1.1 -1.1 -0.2 -1.1 -0.9 -1.0 -0.9 -1.0
Worrier / anxious feelings 0.5 1.0 5.2 1.4 0.5 -0.1 -1.3 0.1 0.1 -0.3 1.0 0.9 0.4 0.9 0.4 1.8 0.7 0.4 0.5 0.4 0.7 0.1 1.5 2.0 -0.0 0.7 0.0 0.5 0.2 1.2 -1.3 1.1 1.1 0.0 0.8 1.3 1.0 1.0 1.2 0.4 0.8 0.9 2.3 1.0 1.2 0.4 1.2 1.1 0.8 1.3 1.0
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.4 1.6 -0.1 -1.0 0.5 -0.4 -0.7 -1.1 -1.3 -0.4 -0.5 -0.8 -0.6 -0.8 -0.4 -0.8 0.9 0.7 -0.8 -0.0 -0.7 -0.6 -0.5 -0.0 0.2 0.0 -1.1 -0.9 -0.6 -0.4 0.6 -0.1 0.0 -0.5 0.1 -0.2 -0.3 -0.3 -1.0 -0.6 -0.6 0.9 0.3 0.1 -0.7 -0.0 -0.3 -0.4 -0.0 -0.1
Falls in the last year 0.5 0.7 4.0 0.9 -0.5 -0.8 -2.0 0.9 0.2 -0.0 0.2 0.7 0.5 0.9 1.5 0.8 0.0 -1.0 -0.1 0.5 0.3 0.3 -0.1 0.8 -0.7 0.2 0.0 0.6 0.1 0.3 -1.6 1.1 0.8 0.0 0.4 1.0 0.7 0.5 1.0 0.3 0.8 0.6 1.6 1.2 1.0 -0.4 1.2 1.0 0.9 1.2 1.1
Hair/balding pattern: Pattern 3 0.2 0.4 2.2 -0.6 -0.1 0.4 1.0 0.8 0.3 0.6 -0.2 0.2 0.1 -0.0 0.7 1.2 1.5 -1.2 -0.1 0.1 0.5 0.6 0.4 -0.4 0.4 0.5 0.0 0.4 0.5 -0.3 1.0 0.2 -0.2 0.0 -0.3 -0.7 -0.5 0.1 -0.5 0.1 -0.2 -0.2 -1.4 -0.9 -0.8 0.5 -0.6 -0.4 -0.4 -0.6 -0.6
Number of live births 1.3 1.9 4.5 -1.7 -0.5 -0.5 1.1 -1.6 -2.1 -1.9 -1.4 -1.8 -1.8 -0.8 -0.7 -0.4 -0.9 0.9 0.4 -1.8 -1.9 -2.1 -1.5 0.2 -1.0 -0.4 0.0 -1.9 -1.7 -1.8 0.5 1.0 -1.2 0.0 -1.3 -1.0 -1.5 -1.6 -2.1 -2.0 -1.8 -1.8 0.4 -1.2 -1.3 0.1 -1.3 -1.4 -1.8 -1.2 -1.5
Forced expiratory volume in 1-second (FEV1) 0.1 0.3 2.1 -0.0 -0.4 0.0 1.2 0.3 0.1 0.2 -0.2 0.3 -0.1 -0.7 -0.1 -0.2 0.0 -0.7 0.0 -0.1 0.3 0.1 -0.0 -1.4 0.6 -0.7 0.0 -0.0 0.4 -0.5 1.2 0.3 -0.2 0.0 -0.1 -0.6 -0.4 -0.2 -0.4 -0.1 -0.4 -0.5 -1.0 -0.9 -0.8 0.5 -0.5 -0.4 -0.6 -0.5 -0.7
Pulse rate 1.0 1.6 5.1 -1.4 -1.4 -1.9 1.4 -0.8 -1.3 -1.0 -1.0 -1.5 -1.1 -1.0 -0.4 -0.3 -0.2 0.3 -0.7 -1.1 -1.8 -1.2 -1.4 0.0 0.1 -1.0 0.0 -1.1 -1.6 -1.8 1.6 -0.3 -1.6 0.0 -1.9 -1.4 -1.4 -1.3 -1.6 -1.1 -1.3 -1.5 -0.3 -2.2 -1.7 1.4 -1.3 -1.2 -1.8 -1.2 -1.8
Happiness 0.6 0.7 3.1 -1.0 0.6 -1.8 1.1 -0.3 -0.3 -0.2 -0.6 -0.8 -0.6 -0.5 0.0 -0.9 -1.0 1.5 -1.5 -0.6 0.6 -0.5 -0.4 0.6 0.5 0.8 0.0 -0.6 -1.1 -0.3 1.0 0.1 -1.5 0.0 -1.3 -1.3 -1.0 -0.7 -0.8 -0.5 -0.6 -0.4 -0.8 -0.5 -0.9 -0.5 -0.9 -0.8 -0.5 -0.9 -0.7
Noisy workplace 0.4 0.5 2.8 0.1 -1.1 0.1 -1.7 -0.3 -0.1 -0.3 0.2 -0.3 0.2 0.0 0.0 -1.0 -0.8 -1.3 -0.2 0.2 -1.0 -0.0 -0.6 -1.5 -1.5 -0.4 0.0 0.0 -0.6 -0.1 -1.7 -0.3 -0.2 0.0 -0.3 0.1 0.1 -0.0 0.0 0.1 0.2 0.3 0.2 1.0 0.5 -1.4 0.4 0.3 0.5 0.3 0.6
Qualifications: A levels/AS levels or equivalent 0.4 0.9 2.9 0.2 1.6 -0.0 1.4 1.2 1.6 1.7 1.2 0.9 1.1 0.8 1.1 0.2 0.9 -0.5 -0.2 1.1 1.1 1.3 0.9 1.5 1.5 1.4 0.0 1.3 0.9 0.8 1.1 0.5 -0.5 0.0 -0.2 -0.1 0.5 0.7 0.4 1.4 0.9 0.7 -0.7 -0.1 0.2 1.1 0.5 0.7 0.7 0.6 0.4
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.4 1.6 -0.3 -0.2 -0.9 -0.6 -0.6 -1.1 -1.1 -0.9 -1.0 -0.9 -0.4 0.2 -0.4 -1.3 1.1 -0.2 -0.9 -0.5 -1.0 -0.6 -0.5 -1.0 -0.3 0.0 -1.0 -0.8 -0.5 -0.3 0.7 -0.5 0.0 -0.6 -0.2 -0.6 -0.6 -0.5 -0.9 -0.7 -0.5 0.5 -0.0 -0.3 -0.9 -0.4 -0.6 -0.5 -0.4 -0.4
Mouth/teeth dental problems: Dentures 1.4 2.4 8.1 1.2 -0.3 -0.1 -1.9 1.2 1.6 0.9 1.2 1.2 1.5 1.7 1.5 -0.5 -1.9 0.3 -0.3 1.5 0.7 1.5 1.5 1.3 -0.0 0.7 0.0 1.2 2.0 1.9 -2.8 -2.2 1.6 0.0 1.5 1.7 1.6 1.5 1.8 1.6 1.7 1.9 0.7 2.8 2.6 -1.3 1.6 1.6 2.2 1.6 2.3
Asthma 0.1 0.2 2.4 0.3 -0.9 0.9 -0.4 0.4 -0.0 0.1 -0.1 0.3 0.1 -0.0 0.0 0.1 -0.5 0.0 -0.3 0.1 -0.3 -0.0 -0.5 -0.6 -0.9 -0.6 0.0 -0.0 -0.3 -0.4 0.4 1.5 0.4 0.0 0.6 0.4 0.3 0.2 -0.2 -0.1 0.1 -0.3 0.8 -0.6 -0.3 1.4 0.2 0.2 -0.2 0.2 -0.1
Medication: Ibuprofen (e.g. Nurofen) 1.3 1.6 6.1 1.8 -0.6 2.2 -1.8 -0.1 0.7 0.7 1.4 1.4 1.1 0.4 -1.4 0.0 -0.4 -0.1 1.2 1.1 -0.9 0.7 0.7 -0.9 -2.4 -0.9 0.0 0.7 -0.3 1.5 -1.7 0.5 2.4 0.0 2.5 1.9 1.9 1.3 1.4 0.8 1.0 1.0 1.7 0.8 1.3 1.0 1.4 1.2 0.9 1.4 1.1
Medication: Cholesterol lowering 0.5 0.7 9.6 -0.2 1.2 -0.2 0.7 0.5 -0.5 -0.4 -0.3 -0.4 -0.4 0.7 0.8 2.0 0.7 3.1 1.2 -0.4 0.5 -0.2 0.5 0.8 0.1 1.8 0.0 -0.4 0.0 -0.2 1.3 1.7 -0.0 0.0 0.0 0.4 -0.1 0.1 -0.3 -0.4 -0.2 -0.4 1.4 -0.7 -0.0 1.6 0.3 0.1 -0.5 0.3 -0.3
Depression (self-reported) 0.7 0.8 2.5 0.6 1.0 1.4 -0.7 1.1 0.6 0.5 1.1 1.1 0.7 1.1 0.9 1.0 -0.4 0.1 0.6 0.7 0.9 1.1 1.1 1.2 1.2 1.6 0.0 0.6 1.2 0.8 -0.4 0.8 0.9 0.0 0.6 1.1 0.7 1.2 0.8 0.7 0.8 0.8 0.9 1.0 1.0 0.4 0.9 0.8 0.8 0.9 0.9
Medication: Lansoprazole 0.2 0.2 2.6 0.2 0.3 0.1 -0.4 -0.0 0.3 0.2 -0.0 -0.1 0.2 -0.4 -1.0 0.0 -0.5 1.6 -0.2 0.2 0.5 0.5 -0.1 -0.4 0.7 0.2 0.0 0.1 -0.4 0.5 -0.2 -1.1 0.1 0.0 0.1 0.0 0.2 0.4 0.6 0.3 0.3 0.4 -0.2 0.3 0.3 -0.4 0.0 0.1 0.4 0.0 0.2
Prospective memory result 0.3 0.4 3.2 -0.3 -0.1 0.7 -0.6 -0.4 -1.0 -1.0 -0.2 -0.9 -0.7 0.2 0.0 -0.5 -1.8 0.5 -0.2 -0.7 -0.9 -0.4 -0.5 -0.6 -1.6 -0.2 0.0 -1.0 -0.4 -0.4 -1.0 -0.2 0.5 0.0 0.3 0.4 -0.2 -0.4 -0.3 -0.8 -0.3 -0.4 0.9 0.7 0.5 -1.2 -0.0 -0.3 -0.1 0.0 0.2
Lung cancer (father) 4.3 5.0 10.7 -2.5 -0.5 -2.4 1.5 -2.8 -2.5 -2.4 -2.4 -2.5 -2.5 -2.7 -2.3 -1.4 -1.5 0.1 -3.3 -2.5 -1.2 -2.7 -2.7 -0.8 0.3 -1.9 0.0 -2.4 -2.5 -2.5 1.7 -0.9 -2.9 0.0 -2.5 -2.8 -2.5 -2.6 -2.7 -2.6 -2.7 -2.3 -1.8 -2.1 -2.2 -1.8 -2.6 -2.6 -2.6 -2.6 -2.6
Illnesses of mother 1.0 1.3 3.6 1.4 0.9 0.9 -1.0 0.3 1.0 1.2 1.5 1.3 1.2 0.8 -0.3 1.3 1.5 -1.9 1.9 1.2 0.1 0.8 0.8 0.5 -0.2 0.4 0.0 1.4 0.2 1.1 -0.9 1.7 1.3 0.0 1.2 1.3 1.5 1.0 0.9 1.1 1.1 1.1 1.0 1.1 1.4 0.7 1.4 1.3 1.1 1.3 1.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.0 0.1 0.6 -0.0 0.0 0.4 0.6 0.4 0.0 0.0 -0.6 -0.1 0.0 -0.1 0.5 0.2 -0.0 -0.7 0.3 0.0 0.3 0.1 0.1 -0.2 0.4 -0.0 0.0 0.0 0.8 -0.0 0.6 0.2 0.0 0.0 0.0 -0.2 -0.3 -0.1 -0.2 -0.1 -0.2 -0.1 -0.4 -0.1 -0.1 0.1 -0.3 -0.2 -0.2 -0.3 -0.2
Pulse wave Arterial Stiffness index 0.1 0.2 1.3 0.2 0.6 0.7 0.5 0.5 0.1 0.1 0.1 0.4 -0.0 0.4 0.3 0.7 0.5 0.4 0.1 -0.0 0.3 0.4 0.5 0.1 0.5 -0.2 0.0 -0.0 1.1 0.1 0.4 -0.7 0.7 0.0 0.8 0.4 0.2 0.3 0.4 0.1 0.0 -0.1 0.1 -0.4 -0.1 0.5 -0.0 -0.0 -0.1 -0.0 -0.1
Impedance of arm (left) 0.2 1.1 7.6 0.6 0.9 -1.1 -1.8 -0.6 -0.8 -1.1 -0.1 -0.1 -0.4 0.7 0.8 2.1 1.9 -1.4 1.9 -0.4 -1.6 -0.9 0.3 2.1 -1.5 -0.6 0.0 -0.0 -0.7 0.1 -1.4 2.1 0.5 0.0 -0.1 0.8 0.3 0.1 0.3 -0.5 0.1 0.0 2.7 0.2 0.6 1.0 0.8 0.5 -0.1 0.8 0.3
Arm fat mass (right) 0.3 1.2 7.0 -0.5 -2.6 -1.0 -1.8 -0.9 -1.5 -2.0 -0.5 -0.6 -1.1 -0.4 -0.1 -1.2 -2.6 -0.3 -0.4 -1.1 -1.8 -1.1 -0.3 -1.0 -1.0 -0.2 0.0 -1.6 -1.2 -0.6 -1.9 -0.7 -0.9 0.0 -1.5 -0.6 -1.0 -0.6 -0.4 -1.4 -0.9 -0.9 0.7 0.4 0.1 -1.6 -0.2 -0.5 -0.6 -0.3 -0.2
Trunk predicted mass 0.8 4.7 17.9 -1.9 -3.8 -0.7 1.8 -1.5 -1.0 -0.8 -1.1 -1.2 -1.3 -3.0 -2.5 -4.2 -3.3 -1.8 -2.7 -1.3 -1.2 -0.9 -2.0 -4.2 1.1 -2.3 0.0 -1.8 -1.6 -2.1 1.1 -2.6 -2.6 0.0 -2.3 -2.9 -2.2 -1.8 -1.9 -1.3 -1.9 -1.8 -4.1 -1.5 -2.2 -2.5 -2.4 -2.1 -1.6 -2.4 -1.9
Standing height 0.8 7.7 15.6 -2.6 -3.4 -2.4 1.5 -2.9 -2.4 -2.2 -2.0 -2.2 -2.5 -3.7 -2.5 -3.8 -2.4 -3.6 -2.2 -2.5 -2.7 -2.4 -2.9 -2.9 0.6 -3.8 0.0 -2.7 -2.6 -3.2 0.9 -2.0 -3.7 0.0 -3.8 -3.7 -3.2 -2.9 -2.9 -2.4 -2.9 -2.7 -4.0 -2.2 -3.1 -2.7 -3.1 -3.0 -2.6 -3.1 -2.8
Length of working week for main job 0.2 0.2 1.7 -0.4 0.3 -0.0 0.6 0.4 0.1 0.3 -0.7 0.2 0.1 -0.4 0.0 -1.3 -0.2 -1.2 -0.1 0.1 0.5 0.1 -0.4 -0.4 -0.5 -0.1 0.0 -0.2 0.1 -0.4 0.6 0.3 0.1 0.0 0.4 -0.4 -0.0 -0.1 -0.5 -0.1 -0.4 -0.4 -1.1 -0.3 -0.5 -0.3 -0.6 -0.4 -0.3 -0.5 -0.4
Exposure to tobacco smoke at home 0.2 0.2 5.1 0.1 -2.3 -0.7 -0.1 0.1 -0.1 -0.1 -0.0 0.1 -0.1 -0.1 -0.0 -1.0 -0.6 -0.6 -0.2 -0.1 -0.7 -0.0 -0.3 -0.2 0.5 0.5 0.0 -0.3 -0.4 -0.0 -0.5 0.3 0.1 0.0 -0.1 -0.1 -0.0 0.2 -0.1 -0.2 -0.0 -0.2 0.1 0.1 -0.1 -0.3 0.1 0.1 0.0 0.1 0.1
Breastfed as a baby 0.2 0.2 1.7 -0.1 1.3 0.9 -0.0 -0.6 -0.2 -0.4 0.5 -0.1 -0.4 -0.0 0.1 0.6 0.6 0.4 0.1 -0.4 0.5 -0.1 0.1 -0.7 -0.5 -0.3 0.0 -0.2 0.1 -0.2 -0.7 -0.4 -0.3 0.0 -0.2 0.0 -0.2 -0.3 0.1 -0.0 0.2 0.3 0.0 0.6 0.2 -1.3 0.0 -0.1 0.4 0.0 0.3
Tense / ‘highly strung’ 0.3 0.4 3.8 -0.2 -1.6 0.0 -0.3 -0.7 -0.7 -0.8 -0.7 -0.5 -0.5 -0.7 -0.5 -0.7 -0.0 -1.9 -0.8 -0.5 -1.2 -0.7 -0.7 -0.3 -1.2 -1.6 0.0 -0.4 -0.8 -0.5 -0.6 -0.0 -0.2 0.0 -0.2 -0.0 -0.1 -0.3 -0.1 -0.6 -0.5 -0.6 0.3 -0.2 -0.4 -0.3 -0.3 -0.3 -0.4 -0.1 -0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.4 2.7 1.3 0.2 1.0 -1.3 0.6 1.2 0.8 1.4 1.4 1.3 0.8 -0.3 1.3 0.8 0.7 0.5 1.3 1.4 1.3 1.1 0.7 1.0 0.4 0.0 1.4 0.6 1.3 -1.2 -0.1 1.2 0.0 1.1 1.4 1.5 1.5 1.6 1.2 1.4 1.6 1.1 1.6 1.6 0.2 1.5 1.5 1.5 1.5 1.6
Hair/balding pattern: Pattern 4 0.6 1.5 7.5 -0.6 -0.8 -0.3 0.5 -1.4 -1.9 -2.2 -1.4 -1.8 -1.6 -0.7 -0.2 -1.7 -2.7 1.0 -1.5 -1.6 -1.1 -1.8 -1.2 -0.4 -0.8 -0.7 0.0 -2.1 -1.0 -0.9 -0.4 -0.9 -1.1 0.0 -1.1 -0.7 -1.2 -1.3 -0.8 -1.8 -1.2 -0.8 1.0 -0.2 -0.6 -1.3 -0.8 -1.0 -1.0 -0.8 -0.8
Birth weight of first child 0.4 0.7 2.7 -0.7 -1.6 -1.0 0.3 -0.5 -0.9 -0.8 -0.6 -0.4 -0.8 -0.6 0.4 -0.5 -0.0 0.6 0.2 -0.8 -0.9 -1.0 -0.5 -0.8 -1.4 -0.5 0.0 -0.9 -1.0 -1.4 0.1 0.3 -1.1 0.0 -1.1 -1.0 -1.0 -0.8 -1.1 -0.9 -1.0 -1.0 -0.4 -1.3 -1.2 0.4 -0.6 -0.8 -1.2 -0.7 -1.1
Peak expiratory flow (PEF) 0.6 1.5 5.2 -1.0 0.2 -0.3 1.8 -0.9 -0.7 -0.4 -1.4 -1.0 -1.0 -1.9 -1.7 -0.7 -0.4 1.1 -1.1 -1.0 0.1 -1.0 -1.6 -1.5 1.2 -1.2 0.0 -1.0 -0.7 -1.4 2.3 0.1 -1.0 0.0 -0.5 -1.3 -1.0 -1.2 -1.5 -1.1 -1.3 -1.4 -1.7 -1.6 -1.6 -0.1 -1.6 -1.4 -1.4 -1.6 -1.6
Pulse wave reflection index 1.3 1.6 8.2 1.3 1.6 2.9 -1.0 0.6 0.9 0.6 0.7 1.1 0.9 0.7 -0.1 0.8 0.3 -0.1 -0.0 0.8 2.1 1.0 1.1 -0.1 0.8 -0.0 0.0 0.8 2.1 1.4 -1.4 -0.3 1.9 0.0 2.3 1.6 1.3 1.1 1.1 0.7 0.9 1.2 0.2 2.2 1.7 -2.1 0.9 0.9 1.5 0.9 1.6
Ever highly irritable/argumentative for 2 days 0.5 0.7 3.2 1.0 0.5 0.9 -1.2 0.2 0.0 -0.3 0.7 0.5 0.2 0.7 0.6 0.8 0.1 -0.0 0.7 0.2 0.7 0.3 1.1 -0.7 -0.6 0.4 0.0 0.3 0.7 0.8 -1.8 0.4 0.5 0.0 0.1 0.9 0.6 0.7 1.1 0.3 0.7 0.8 1.5 1.6 1.4 -1.1 1.1 0.9 1.0 1.1 1.2
Loud music exposure frequency 1.0 1.1 2.7 -1.0 -1.0 -0.5 0.2 -1.6 -1.1 -1.4 -0.8 -1.2 -1.2 -1.3 -1.4 -1.0 -1.0 -1.1 -1.2 -1.2 -1.6 -1.1 -1.0 -0.6 1.0 -1.5 0.0 -1.2 -0.6 -0.8 -0.4 -1.6 -1.0 0.0 -1.1 -0.9 -1.1 -0.8 -0.9 -1.1 -1.1 -1.1 -1.0 -0.4 -0.9 -1.6 -1.1 -1.1 -0.8 -1.1 -0.8
Qualifications: O levels/GCSEs or equivalent 0.6 1.0 4.8 -0.1 0.9 -1.2 1.5 1.6 1.5 1.8 0.9 0.8 1.0 1.2 1.9 -1.1 -0.2 -0.3 -0.0 1.0 0.7 1.3 0.7 2.0 0.9 2.2 0.0 1.0 0.9 0.6 1.3 0.4 -0.8 0.0 -0.3 -0.5 0.2 0.5 -0.1 1.4 0.7 0.4 -1.1 -0.5 -0.3 1.6 0.2 0.5 0.4 0.3 0.1
Mouth/teeth dental problems: Bleeding gums 0.7 1.0 2.6 -0.5 -1.5 -1.2 0.1 -1.1 -1.1 -1.0 -0.7 -0.5 -1.0 -1.1 -1.4 -1.1 -1.3 -0.7 -0.3 -1.0 -1.6 -0.9 -1.0 0.5 0.9 -1.3 0.0 -1.3 -1.3 -0.9 0.2 0.5 -0.9 0.0 -0.9 -0.7 -0.7 -0.6 -1.3 -1.2 -1.1 -1.4 -0.4 -1.3 -1.2 0.2 -0.8 -0.9 -1.3 -0.9 -1.1
Blood clot in the leg (DVT) 0.6 0.8 6.8 0.1 -1.1 -0.6 -0.3 -0.1 1.0 0.8 0.2 0.1 0.7 -0.2 -0.3 -2.1 -1.3 -1.3 -0.6 0.7 -0.0 0.8 -0.6 -0.9 -0.2 -0.8 0.0 0.6 0.5 0.9 -1.0 -2.6 0.2 0.0 0.2 0.1 0.5 -0.1 0.4 0.9 0.8 0.9 -1.4 1.5 1.0 -1.9 0.1 0.2 1.2 0.0 0.9
Medication: Paracetamol 1.0 1.7 7.4 1.6 0.3 1.7 0.2 1.1 0.9 1.1 0.6 1.5 1.2 0.9 -0.8 1.3 1.2 1.9 2.2 1.2 0.9 1.0 1.2 0.5 0.3 0.8 0.0 0.9 0.8 1.2 0.9 1.9 2.3 0.0 2.6 1.9 1.9 1.6 1.1 0.8 0.8 0.6 2.0 -0.1 0.8 2.7 1.3 1.2 0.4 1.3 0.6
Headache pain in last month 0.3 0.5 2.0 0.7 1.0 0.9 -0.2 0.1 0.8 0.8 0.6 1.0 0.8 0.6 -0.9 0.1 -0.5 0.3 1.2 0.8 -0.3 0.6 0.2 0.8 0.4 -0.3 0.0 0.5 0.5 0.9 -0.2 -0.5 1.2 0.0 1.4 1.2 1.3 0.9 0.4 0.7 0.7 0.5 0.7 0.6 0.9 0.5 0.7 0.8 0.7 0.8 0.7
Medication for cholesterol, blood pressure or diabetes 0.3 0.4 4.2 0.4 -1.1 0.6 -0.3 -0.2 0.5 0.6 0.4 0.5 0.5 -0.5 -0.6 -1.8 -0.6 -2.0 -1.1 0.5 -0.4 0.2 -0.4 -1.1 -0.7 -1.1 0.0 0.4 -0.3 0.0 -0.9 -0.8 0.1 0.0 0.1 -0.3 0.2 0.1 0.2 0.4 0.2 0.2 -0.9 0.4 0.0 -0.5 -0.1 0.1 0.4 -0.0 0.3
Glaucoma (self-reported) 0.2 0.3 0.9 0.6 0.4 0.8 -0.4 0.2 0.5 0.5 0.5 0.5 0.5 0.4 -0.5 0.3 0.1 -0.2 0.1 0.5 0.5 0.5 0.6 0.1 -0.1 0.9 0.0 0.5 -0.3 0.6 -0.2 0.7 0.5 0.0 0.6 0.6 0.7 0.7 0.4 0.5 0.6 0.8 1.0 0.5 0.7 0.5 0.7 0.7 0.5 0.7 0.6
Gout (self-reported) 0.2 0.2 1.1 -0.4 -0.7 -0.5 0.1 0.5 -0.3 -0.2 -1.0 -0.2 -0.2 0.2 0.6 -0.3 0.3 -0.4 0.5 -0.2 -0.6 -0.1 -0.6 0.9 0.5 0.5 0.0 -0.4 0.3 -0.2 0.5 0.7 -0.5 0.0 -0.4 -0.4 -0.4 -0.2 -0.6 -0.4 -0.4 -0.9 -0.1 -0.7 -0.7 0.7 -0.4 -0.3 -0.6 -0.4 -0.6
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 1.8 -0.2 -0.3 0.2 -0.5 -1.0 -0.8 -0.9 -0.3 -0.5 -0.8 -0.2 -0.4 0.1 -0.0 -0.4 0.3 -0.8 -1.3 -0.9 -0.7 1.4 -0.2 -0.8 0.0 -0.7 -0.3 -0.2 -0.4 0.2 0.1 0.0 -0.0 0.3 -0.1 -0.5 -0.5 -0.6 -0.3 -0.5 0.7 -0.1 -0.0 -0.1 -0.1 -0.2 -0.3 -0.1 -0.2
Medication: Amlodipine 1.2 1.7 6.3 -2.1 0.9 -2.4 1.9 -0.7 -1.1 -0.9 -1.5 -1.2 -1.3 -0.3 0.4 -0.6 -0.4 -0.5 -0.3 -1.3 -1.4 -1.2 -1.7 2.5 0.9 -0.5 0.0 -1.3 -0.5 -1.5 1.9 -0.4 -1.4 0.0 -1.1 -1.1 -1.3 -1.4 -2.0 -1.3 -1.5 -1.6 -0.8 -1.8 -1.4 0.7 -1.4 -1.4 -1.7 -1.4 -1.6
Medication: Ventolin 100micrograms inhaler 0.8 1.0 3.7 -1.1 -1.8 -0.8 0.8 -0.3 -0.4 -0.2 -0.5 -0.1 -0.3 -0.8 -0.5 -1.3 -1.0 1.4 -1.7 -0.3 -0.5 -0.7 -1.4 -1.9 -0.8 -0.1 0.0 -0.6 -1.7 -1.6 1.4 0.3 -1.0 0.0 -0.7 -1.3 -0.9 -0.9 -1.7 -0.7 -0.9 -0.9 -1.1 -1.3 -1.3 0.2 -0.9 -0.8 -1.0 -1.0 -1.1
Birth weight 0.2 0.4 1.6 -0.7 -0.5 -0.2 0.0 -1.0 -0.7 -0.7 -0.4 -0.4 -0.8 -0.6 -0.7 -0.3 -0.5 -0.4 -0.0 -0.8 -1.0 -0.8 -0.4 -0.8 -0.5 -1.2 0.0 -0.8 -0.8 -0.8 -0.1 -0.1 -1.0 0.0 -0.8 -0.8 -0.7 -0.7 -0.9 -0.6 -0.6 -0.7 -0.5 -0.5 -0.7 -0.3 -0.6 -0.6 -0.6 -0.6 -0.6
Chronic bronchitis/emphysema (mother) 1.0 1.2 5.4 -0.5 -2.3 -1.0 -0.0 -0.7 -1.3 -1.5 -1.0 -1.1 -1.0 -0.8 -0.7 0.4 -0.2 0.1 1.1 -1.0 -2.1 -1.0 -0.9 -1.2 -0.7 -1.0 0.0 -1.2 -0.9 -1.4 0.7 -0.2 -0.6 0.0 -0.8 -0.5 -1.0 -0.6 -0.6 -1.3 -1.3 -1.4 0.7 -2.0 -1.2 1.9 -0.7 -0.9 -1.7 -0.7 -1.5
High blood pressure (siblings) 0.1 0.2 1.6 -0.3 0.4 0.1 0.2 -0.3 0.3 0.4 -0.5 -0.1 0.1 -0.2 -1.0 0.4 0.9 0.4 -0.9 0.1 0.6 0.3 0.3 0.4 0.9 -0.1 0.0 0.3 0.2 0.5 0.5 -0.6 -0.3 0.0 -0.1 -0.4 -0.1 -0.1 0.2 0.1 -0.0 0.1 -1.3 -0.1 -0.2 -0.4 -0.3 -0.3 0.1 -0.4 -0.2
Forced vital capacity (FVC), Best measure 0.1 0.3 1.7 0.5 0.1 0.4 0.5 1.0 0.8 0.8 0.0 0.5 0.6 0.3 0.8 0.1 0.1 -1.3 0.3 0.6 0.7 0.7 0.4 0.4 0.9 0.2 0.0 0.6 1.1 0.5 0.3 0.3 0.4 0.0 0.4 0.2 0.2 0.4 0.2 0.6 0.4 0.5 -0.4 0.3 0.3 0.4 0.1 0.3 0.4 0.2 0.3
Body fat percentage 0.3 1.3 5.8 -0.5 -2.0 -1.1 -2.1 -1.2 -1.8 -2.4 -0.7 -1.0 -1.4 -0.1 0.1 0.0 -1.7 0.2 0.6 -1.4 -2.3 -1.4 -0.3 -0.1 -1.7 -0.2 0.0 -1.7 -1.4 -0.6 -1.9 -0.2 -0.7 0.0 -1.5 -0.2 -1.0 -0.7 -0.5 -1.6 -1.0 -1.1 1.6 0.2 0.1 -0.9 -0.1 -0.5 -0.8 -0.2 -0.2
Leg fat percentage (right) 0.2 0.7 5.3 0.0 -2.3 -0.1 -1.8 -0.6 -1.3 -1.7 -0.4 -0.5 -0.9 0.0 -0.2 0.0 -1.5 0.6 0.6 -0.9 -1.7 -0.8 0.0 -1.0 -1.5 0.0 0.0 -1.2 -0.8 -0.3 -1.5 -0.2 0.1 0.0 -0.5 0.2 -0.4 -0.2 -0.0 -1.1 -0.6 -0.7 1.4 0.1 0.1 -0.3 0.1 -0.2 -0.6 0.0 -0.1
Arm fat-free mass (right) 0.7 3.7 13.1 -1.9 -3.3 -0.8 1.2 -1.5 -1.2 -1.1 -0.9 -1.3 -1.4 -2.3 -2.0 -3.6 -3.4 -1.1 -2.3 -1.4 -1.2 -1.0 -1.6 -2.6 1.4 -1.5 0.0 -1.9 -1.4 -1.8 0.6 -2.7 -2.5 0.0 -2.4 -2.6 -2.2 -1.6 -1.8 -1.4 -1.8 -1.8 -3.3 -1.1 -1.8 -2.3 -2.1 -1.9 -1.4 -2.1 -1.6
Exposure to tobacco smoke outside home 0.6 0.8 9.6 -0.1 -3.1 -1.2 0.1 -0.4 -0.4 -0.3 -0.4 -0.6 -0.3 -1.1 -1.2 -1.5 -1.1 -0.4 -1.0 -0.3 -1.1 -0.3 -1.0 -2.1 0.7 -1.2 0.0 -0.5 -0.6 -0.8 -0.2 -1.0 -0.6 0.0 -0.7 -0.7 -0.4 -0.4 -0.1 -0.5 -0.6 -0.9 -1.0 -0.9 -0.9 -0.2 -0.5 -0.5 -0.7 -0.5 -0.7
Comparative body size at age 10 0.2 0.7 4.2 -0.9 -0.6 -0.8 1.6 0.2 0.0 0.4 -0.3 -0.4 -0.3 -0.8 -0.4 -0.9 -0.5 0.8 -0.8 -0.3 0.3 -0.0 -0.5 -0.2 1.8 0.8 0.0 -0.3 -0.2 -0.4 2.0 -0.7 -1.1 0.0 -0.8 -1.3 -0.9 -0.5 -0.6 -0.2 -0.5 -0.6 -1.6 -1.3 -1.2 0.3 -1.1 -0.8 -0.7 -1.0 -1.0
Number of full brothers 0.3 0.3 1.4 0.4 -0.4 0.5 -0.1 0.7 0.7 0.8 0.1 0.7 0.5 0.1 0.3 -1.2 -1.0 -0.3 -0.9 0.5 0.8 0.6 -0.2 -1.2 -0.9 -0.4 0.0 0.4 0.4 0.3 -0.2 -0.0 0.7 0.0 1.1 0.3 0.5 0.6 0.5 0.6 0.4 0.5 -0.7 0.8 0.4 -0.6 0.2 0.3 0.7 0.2 0.5
Worry too long after embarrassment 0.3 0.5 4.9 0.1 -1.4 -1.1 -0.7 -1.1 -0.5 -0.8 0.1 -0.2 -0.4 -1.1 -1.2 -0.2 -0.2 -0.1 -1.0 -0.4 0.4 -0.6 0.0 -1.1 1.3 -1.3 0.0 -0.3 -0.5 -0.1 -1.3 -0.6 -0.8 0.0 -1.0 -0.5 -0.4 -0.3 0.2 -0.5 -0.3 0.1 -0.3 0.8 0.1 -2.2 -0.3 -0.4 0.2 -0.3 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 2.0 0.6 -0.1 0.7 -0.4 0.8 -0.0 -0.4 0.3 0.5 0.3 0.9 0.9 0.9 -0.2 0.3 0.1 0.3 0.9 0.7 0.4 1.3 1.2 0.9 0.0 0.2 0.9 0.5 -0.6 0.4 0.7 0.0 0.5 0.9 0.5 1.0 0.7 0.1 0.5 0.4 1.4 0.9 0.7 -0.1 0.8 0.7 0.6 0.9 0.8
Wheeze or whistling in the chest in last year 0.3 0.5 6.4 -0.1 -2.5 -0.3 -1.1 -0.6 -0.4 -0.5 -0.6 -0.2 -0.2 -0.7 -1.3 -1.3 -1.2 -1.1 -0.5 -0.2 -1.4 -0.4 -0.7 -1.5 -0.4 -1.0 0.0 -0.5 -1.1 -0.4 -0.6 -0.1 -0.3 0.0 -0.4 -0.2 -0.0 -0.1 -0.2 -0.5 -0.4 -0.4 0.4 -0.2 -0.0 0.0 -0.1 -0.1 -0.4 -0.1 -0.2
Number of children fathered 1.7 1.9 5.2 1.5 1.6 0.6 -0.6 2.1 1.8 1.8 1.4 1.7 1.6 1.9 2.3 0.3 0.0 -0.4 0.3 1.6 1.1 1.9 1.3 1.0 -0.2 1.2 0.0 1.6 2.2 1.6 -0.5 -0.2 1.7 0.0 1.6 1.4 1.4 1.5 1.3 1.8 1.6 1.7 0.7 1.0 1.4 1.1 1.4 1.6 1.5 1.4 1.4
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 2.4 -1.2 0.4 -0.8 -0.0 -1.0 -1.5 -1.4 -1.0 -1.4 -1.2 -0.5 -0.1 0.4 -0.3 0.7 -0.6 -1.2 -0.9 -1.3 -0.5 1.1 0.3 0.2 0.0 -1.1 -1.0 -1.0 0.3 0.7 -1.2 0.0 -1.6 -0.8 -1.2 -1.1 -0.9 -1.2 -1.0 -1.1 0.5 -0.6 -0.6 -0.2 -0.6 -0.9 -1.0 -0.6 -0.8
Age at first live birth 1.0 1.7 3.2 1.7 1.2 0.2 -0.8 1.4 1.6 1.5 1.5 1.8 1.6 1.6 1.5 -0.1 0.7 -1.3 1.2 1.6 1.2 1.4 1.1 0.1 -0.4 0.9 0.0 1.5 1.2 1.6 -1.0 1.2 1.2 0.0 0.9 1.3 1.3 1.4 1.4 1.6 1.8 1.5 1.1 1.5 1.4 0.3 1.6 1.7 1.8 1.7 1.7
Pulse wave peak to peak time 0.2 0.2 1.4 -0.2 -0.6 -0.9 -0.4 -0.5 -0.1 0.0 -0.1 -0.3 0.1 -0.5 -0.3 -0.8 -0.4 -0.7 -0.2 0.1 -0.2 -0.4 -0.5 -0.2 -0.3 0.2 0.0 0.1 -1.2 -0.1 -0.3 0.7 -0.8 0.0 -0.9 -0.5 -0.3 -0.4 -0.4 -0.1 -0.0 0.1 -0.3 0.4 0.1 -0.7 -0.0 -0.0 0.2 -0.0 0.1
Health satisfaction 1.1 1.4 5.1 -1.3 -1.9 -1.6 0.8 -0.6 -1.3 -1.4 -0.9 -1.3 -1.1 -0.6 -0.1 -1.3 -1.6 1.6 -1.1 -1.1 -1.4 -1.1 -0.6 0.1 0.5 0.6 0.0 -1.4 -1.5 -1.0 0.8 -0.8 -2.1 0.0 -2.3 -1.5 -1.6 -0.8 -1.1 -1.5 -1.3 -1.4 0.1 -1.3 -1.2 0.3 -1.0 -1.1 -1.4 -1.1 -1.3
Shortness of breath walking on level ground 0.8 1.0 6.5 1.3 -1.3 0.6 -2.5 -0.1 -0.6 -1.1 0.6 0.1 0.1 0.4 -0.0 1.1 -0.2 0.9 1.3 0.1 -0.7 -0.2 0.5 -1.9 -1.9 -0.4 0.0 -0.1 -0.3 0.3 -2.1 -0.3 0.9 0.0 0.3 1.4 0.7 0.7 1.1 -0.3 0.3 0.4 2.5 0.9 1.0 -0.0 1.1 0.8 0.4 1.1 0.8
Qualifications: College or University degree 0.1 0.3 2.5 0.4 0.8 0.3 0.0 -0.2 0.6 0.4 0.2 0.3 0.3 -0.7 -0.8 -0.3 0.8 -0.7 -0.9 0.3 0.9 0.3 0.0 -0.5 1.6 -0.9 0.0 0.6 0.7 0.3 -0.2 -0.4 -0.1 0.0 0.0 -0.1 0.2 0.1 0.4 0.5 0.4 0.5 -0.9 0.6 0.1 -1.1 0.0 0.1 0.5 0.1 0.4
Eye problems/disorders: None of the above 0.6 0.7 4.5 -0.8 -0.8 -2.1 0.7 -0.1 -0.0 -0.1 -0.8 -0.7 -0.4 -0.6 0.6 -1.7 -1.6 0.2 -1.7 -0.4 -0.1 -0.4 -1.0 -0.2 0.1 -0.5 0.0 -0.4 0.0 -0.6 0.5 -1.2 -0.9 0.0 -1.0 -1.0 -0.8 -0.9 -0.6 -0.2 -0.5 -0.7 -1.8 -0.2 -0.7 -0.8 -0.9 -0.7 -0.3 -0.8 -0.4
Mouth/teeth dental problems: Loose teeth 0.5 0.5 5.5 -1.0 0.0 0.8 0.6 -0.3 -0.4 -0.6 -0.7 -0.9 -0.5 -0.6 -0.8 0.3 -0.5 1.2 -0.7 -0.5 0.0 -0.2 -0.7 -0.3 0.7 0.3 0.0 -0.6 -0.0 -0.3 0.8 -2.4 -0.5 0.0 -0.4 -0.6 -0.8 -0.4 -0.2 -0.6 -0.8 -0.7 -1.3 -0.7 -0.8 -0.6 -1.1 -0.9 -0.7 -1.0 -0.9
Emphysema/chronic bronchitis 0.6 0.7 3.3 0.4 1.0 0.3 -0.6 1.2 0.3 0.1 0.2 0.2 0.5 1.4 1.3 1.3 -0.0 0.9 0.6 0.5 0.7 0.8 0.4 1.8 0.5 1.8 0.0 0.5 0.7 0.7 -0.1 0.6 0.8 0.0 0.6 1.0 0.5 0.9 0.6 0.5 0.8 0.7 1.7 0.7 0.9 0.9 1.0 0.9 0.7 1.0 0.8
Medication for pain relief, constipation, heartburn 1.3 2.3 7.6 -1.9 -0.9 -2.4 0.8 -0.8 -0.8 -0.9 -0.8 -1.3 -1.2 -1.1 1.0 -2.4 -1.6 -2.5 -2.1 -1.2 -0.9 -0.9 -1.3 -0.6 0.1 -1.2 0.0 -1.1 -0.4 -1.6 0.1 -2.6 -2.4 0.0 -2.6 -2.2 -2.1 -1.7 -1.5 -0.8 -1.1 -1.1 -2.8 -0.7 -1.4 -2.0 -1.7 -1.6 -0.9 -1.7 -1.2
Neck or shoulder pain in last month 0.2 0.3 2.1 0.2 0.0 1.1 -0.7 -0.6 -0.5 -0.5 -0.2 -0.3 -0.3 -0.2 -1.2 -0.7 -1.5 -0.1 0.2 -0.3 -0.7 -0.3 0.1 -1.0 -0.7 -0.5 0.0 -0.6 -0.2 0.5 -0.7 0.3 0.6 0.0 0.4 0.5 0.3 0.2 0.4 -0.4 -0.1 0.0 1.1 0.6 0.4 -0.8 0.2 0.1 0.1 0.3 0.2
Medication: Blood pressure 0.5 0.9 4.6 0.0 1.9 -0.4 0.7 1.1 0.6 0.6 0.3 0.3 0.4 1.2 1.4 2.1 1.4 1.4 1.4 0.4 1.2 0.7 1.4 1.6 1.1 1.7 0.0 0.6 1.4 0.9 1.2 0.6 0.2 0.0 0.4 0.6 0.3 0.6 0.9 0.5 0.5 0.7 0.7 -0.4 0.1 1.3 0.5 0.5 0.2 0.5 0.1
Angina (self-reported) 0.2 0.3 1.5 0.1 1.2 0.1 -0.7 -0.6 -0.7 -1.1 0.0 0.0 -0.7 0.2 -0.1 1.0 0.0 -0.1 -0.2 -0.7 0.3 -0.4 0.5 1.0 0.7 -0.1 0.0 -0.5 0.3 0.1 -1.0 0.3 0.2 0.0 -0.1 0.4 -0.2 0.0 0.2 -0.4 -0.1 0.2 1.2 0.7 0.5 -0.8 0.2 -0.0 0.1 0.2 0.2
Migraine (self-reported) 0.6 0.8 4.8 0.6 2.2 0.1 -0.7 0.7 0.8 0.5 0.4 0.8 0.6 1.4 1.4 0.8 0.4 -1.1 0.3 0.6 0.6 0.6 0.8 2.0 -0.1 1.0 0.0 0.8 0.8 0.9 -0.8 1.0 0.7 0.0 0.7 0.7 0.7 0.6 0.4 0.7 0.8 1.1 1.0 1.4 1.5 -0.1 0.9 0.9 1.0 0.9 1.1
Medication: Ibuprofen 0.6 0.7 6.5 0.9 -0.6 1.7 -1.2 -0.6 -0.3 -0.3 0.3 0.3 -0.0 -0.1 -1.3 0.0 -0.2 -0.3 1.1 -0.0 -1.6 -0.3 -0.0 -0.8 -2.5 -1.3 0.0 -0.3 -0.8 0.3 -0.8 0.6 1.5 0.0 1.6 1.1 0.9 0.3 0.4 -0.2 -0.0 -0.0 1.7 -0.4 0.2 1.4 0.6 0.3 -0.3 0.5 -0.1
Medication: Allopurinol 0.3 0.4 1.2 0.4 -0.4 0.5 -0.9 1.0 0.7 0.6 0.2 0.9 0.7 0.9 0.9 0.1 0.8 -0.9 0.8 0.7 0.1 0.9 0.4 0.7 0.5 0.7 0.0 0.6 1.1 0.7 -0.6 0.0 0.5 0.0 0.4 0.6 0.7 0.7 0.8 0.7 0.8 0.5 0.6 0.6 0.6 0.5 0.6 0.7 0.7 0.7 0.7
Medication: Omeprazole 0.4 0.5 5.5 0.2 -1.1 -1.4 -0.1 1.0 0.5 0.5 0.4 0.5 0.4 1.1 2.1 0.2 0.5 -0.3 0.5 0.4 -1.0 0.3 0.6 0.3 -1.5 0.3 0.0 0.5 0.3 -0.2 0.7 0.4 0.3 0.0 -0.0 0.3 0.2 0.3 0.5 0.6 0.4 0.0 0.6 -0.8 -0.4 2.3 0.5 0.4 -0.0 0.5 -0.1
Medication: Seretide 50 evohaler 1.3 1.5 4.7 -1.1 -1.2 0.1 0.7 -0.8 -1.1 -0.6 -1.0 -1.0 -1.1 -1.8 -1.6 -0.9 -0.9 0.9 -1.2 -1.1 -0.6 -1.2 -1.9 -2.2 -0.0 -0.5 0.0 -1.3 -2.0 -1.9 1.9 0.5 -0.8 0.0 -0.6 -1.1 -1.0 -1.2 -1.6 -1.2 -1.4 -1.5 -1.1 -1.6 -1.5 0.3 -1.4 -1.3 -1.5 -1.4 -1.5
Mean time to correctly identify matches 0.5 0.9 3.4 1.1 0.1 1.7 -1.3 0.8 0.4 0.2 0.7 0.3 0.9 0.7 -0.2 1.9 1.1 1.7 1.0 0.9 0.6 0.8 0.8 -0.6 0.3 1.1 0.0 0.9 0.4 0.7 -0.4 0.4 1.3 0.0 1.1 1.5 1.0 1.2 1.3 0.6 0.8 0.9 1.8 0.6 1.1 0.8 1.2 1.1 0.7 1.2 0.8
Heart disease (mother) 0.6 0.7 4.9 0.9 1.1 -0.4 -1.2 0.2 0.9 0.6 0.7 0.9 0.6 0.7 0.0 0.5 -0.5 2.2 -0.1 0.6 0.5 0.5 1.2 0.9 -0.6 0.7 0.0 0.6 0.1 1.4 -1.0 -0.7 0.6 0.0 0.4 0.7 0.9 0.9 1.2 1.0 1.0 1.0 0.9 0.9 1.1 0.3 0.8 0.9 1.0 0.9 0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 4.8 5.7 10.0 -2.6 -1.8 -1.3 1.5 -2.8 -2.4 -2.0 -2.2 -2.6 -2.6 -3.2 -2.8 -2.0 -1.7 0.7 -1.8 -2.6 -2.3 -2.7 -2.7 -2.4 -1.4 -2.5 0.0 -2.6 -3.0 -3.1 2.1 -1.5 -2.3 0.0 -2.1 -2.5 -2.4 -2.9 -2.5 -2.4 -2.8 -2.8 -2.1 -3.1 -2.9 -0.1 -2.8 -2.9 -3.0 -2.8 -3.1
Whole body fat mass 0.6 2.3 7.9 -1.3 -2.8 -1.5 -1.3 -1.7 -2.2 -2.7 -1.1 -1.4 -1.9 -1.0 -0.6 -1.3 -2.8 -0.5 -0.5 -1.9 -2.5 -1.8 -1.0 -1.0 -1.1 -0.7 0.0 -2.3 -1.9 -1.4 -1.4 -0.9 -1.7 0.0 -2.3 -1.2 -1.8 -1.3 -1.2 -2.1 -1.7 -1.6 0.2 -0.3 -0.7 -1.8 -0.9 -1.3 -1.3 -1.0 -0.9
Leg fat mass (right) 0.5 1.9 9.0 -1.0 -3.0 -0.8 -1.3 -1.4 -2.0 -2.3 -0.9 -1.2 -1.7 -1.0 -0.9 -1.3 -2.6 -0.4 -0.4 -1.7 -2.3 -1.4 -0.8 -1.6 -0.9 -0.6 0.0 -2.1 -1.5 -1.2 -1.3 -0.9 -1.2 0.0 -1.8 -1.0 -1.5 -1.1 -1.0 -1.8 -1.5 -1.4 0.2 -0.4 -0.7 -1.5 -0.8 -1.1 -1.2 -0.9 -0.9
Arm predicted mass (right) 0.8 4.3 13.8 -2.2 -3.5 -0.9 1.3 -1.6 -1.5 -1.4 -1.1 -1.6 -1.6 -2.5 -2.0 -3.7 -3.5 -0.9 -2.5 -1.6 -1.3 -1.2 -1.9 -2.9 1.2 -1.6 0.0 -2.1 -1.5 -2.1 0.6 -3.0 -2.7 0.0 -2.6 -2.7 -2.4 -1.8 -2.0 -1.6 -2.0 -2.0 -3.4 -1.2 -1.9 -2.5 -2.3 -2.1 -1.6 -2.3 -1.8
Pulse rate, automated reading 0.3 1.1 4.6 -1.1 -0.6 -2.1 1.0 -0.6 -1.2 -1.1 -0.6 -1.0 -1.0 -0.4 0.3 -0.2 -0.2 0.4 -0.3 -1.0 -1.9 -1.2 -0.9 1.2 -0.2 -0.2 0.0 -1.1 -1.2 -1.5 1.1 0.1 -1.2 0.0 -1.5 -1.0 -1.1 -1.1 -1.5 -1.0 -1.1 -1.4 0.2 -1.9 -1.1 1.4 -0.9 -0.9 -1.6 -0.8 -1.4
Alcohol intake frequency. 0.5 1.1 5.4 0.6 1.9 0.5 -0.4 1.1 0.8 0.4 0.2 0.6 0.8 1.5 2.0 -0.1 -1.1 -1.1 -0.6 0.8 0.9 0.9 0.3 0.9 -0.4 1.4 0.0 0.7 1.6 1.2 -1.1 -0.4 1.0 0.0 0.7 0.9 0.6 0.6 0.8 0.8 1.1 1.3 0.8 2.3 1.6 -1.6 1.0 1.0 1.6 1.0 1.6
Comparative height size at age 10 1.8 9.7 17.5 -3.3 -3.1 -1.7 2.5 -3.0 -2.9 -2.6 -2.7 -2.9 -3.1 -3.9 -2.9 -3.5 -1.7 -1.9 -2.2 -3.1 -3.2 -2.8 -2.6 -3.5 0.3 -3.4 0.0 -3.2 -2.9 -3.8 2.2 -2.3 -4.1 0.0 -4.1 -4.2 -3.8 -3.3 -3.2 -3.0 -3.6 -3.6 -3.8 -3.8 -4.0 -1.0 -3.7 -3.6 -3.7 -3.7 -3.8
Number of full sisters 0.2 0.3 1.4 -0.4 1.1 -0.1 1.0 -0.5 -0.6 -0.3 -0.4 -0.4 -1.0 0.2 0.3 -0.2 -0.6 0.8 -0.3 -1.0 -0.1 -0.4 -0.5 1.1 0.0 -0.0 0.0 -0.8 -0.0 -0.5 0.8 1.2 -0.0 0.0 0.1 0.0 -0.3 -0.6 -1.0 -0.4 -0.3 -0.4 0.4 -0.3 -0.3 0.2 -0.1 -0.4 -0.4 -0.2 -0.3
Suffer from ‘nerves’ 0.7 1.1 5.0 1.1 1.3 1.4 0.2 0.8 0.5 0.6 0.9 0.8 0.8 0.5 -0.3 2.2 2.2 0.5 1.5 0.8 1.7 0.8 1.0 0.6 1.7 1.7 0.0 1.0 0.6 0.8 0.2 2.0 0.8 0.0 0.8 1.1 1.0 1.2 1.1 0.6 0.8 0.7 1.1 0.6 0.7 0.8 1.0 1.0 0.7 1.0 0.8
Overall health rating 0.3 0.7 3.8 -0.6 -1.9 0.4 -0.4 -0.6 -1.3 -1.5 -0.8 -0.8 -0.9 -0.3 -0.7 0.2 -1.4 0.9 0.6 -0.9 -1.9 -0.7 -0.9 0.1 -0.3 -0.5 0.0 -1.2 -0.6 -0.9 -0.1 -0.7 0.1 0.0 -0.2 0.4 -0.3 -0.3 -0.6 -1.1 -0.9 -1.2 1.1 -0.9 -0.4 0.7 -0.2 -0.5 -1.1 -0.2 -0.7
Chest pain or discomfort 2.0 2.9 6.5 2.2 -0.8 1.1 -2.4 1.3 1.8 1.0 2.2 2.2 1.8 1.6 0.7 1.4 -0.2 0.3 1.0 1.8 0.2 1.9 1.5 -0.8 -0.0 -0.2 0.0 1.7 2.1 1.8 -2.2 -2.0 2.5 0.0 1.9 2.5 2.1 2.2 2.4 1.8 1.9 1.8 1.4 2.0 2.2 0.3 2.0 2.0 2.0 2.0 2.1
Had major operations 1.4 1.7 3.8 -1.3 -0.2 -0.2 0.8 -1.8 -1.6 -1.5 -1.5 -1.6 -1.5 -1.5 -1.4 -1.3 -1.4 0.2 -0.1 -1.5 -2.0 -1.5 -1.8 -1.5 -0.9 -1.4 0.0 -1.6 -1.8 -1.6 0.5 -0.5 -1.2 0.0 -1.5 -1.2 -1.4 -1.6 -1.4 -1.4 -1.4 -1.7 -0.7 -1.1 -1.1 -0.8 -1.2 -1.4 -1.4 -1.2 -1.2
Age at last live birth 0.2 0.3 2.2 0.3 0.1 -0.5 -0.9 -0.1 -0.3 -0.4 0.4 0.1 -0.1 0.4 1.1 -1.2 -0.6 -1.5 0.1 -0.1 -0.7 -0.5 -0.2 -0.4 -1.0 0.3 0.0 -0.3 -0.3 -0.0 -1.2 0.9 -0.4 0.0 -0.8 0.1 -0.2 -0.1 0.2 -0.1 0.2 0.1 1.0 0.6 0.3 -0.5 0.5 0.4 0.3 0.6 0.5
Family relationship satisfaction 0.8 1.0 6.3 -1.0 -0.1 -2.5 0.5 -0.7 -1.0 -1.0 -1.4 -1.3 -1.0 -0.9 -0.0 -0.4 -0.4 1.2 -1.6 -1.0 0.6 -1.0 -0.9 -0.1 0.1 0.1 0.0 -0.9 -1.5 -0.7 0.4 0.3 -2.0 0.0 -2.0 -1.5 -1.2 -1.1 -0.7 -1.0 -0.9 -0.8 -0.2 -0.5 -0.9 -0.9 -0.8 -0.9 -0.8 -0.8 -0.8
Leg pain on walking 0.4 0.6 3.0 0.8 -0.3 0.6 0.2 0.9 0.9 1.0 0.6 0.8 0.8 0.3 -0.1 0.8 1.2 1.7 1.6 0.9 0.5 0.7 0.5 -0.9 -0.5 0.5 0.0 0.8 0.3 0.4 0.7 0.7 0.8 0.0 0.8 0.8 0.9 1.0 0.5 0.7 0.6 0.1 0.2 -0.5 -0.0 1.7 0.5 0.6 0.3 0.5 0.2
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 3.3 -0.8 0.2 0.4 1.0 0.2 0.4 1.0 -0.5 -0.0 0.1 -0.5 -0.8 -0.5 0.3 -0.6 -0.4 0.1 0.2 0.2 -0.1 -0.8 0.1 0.1 0.0 0.2 -0.4 -0.1 1.8 0.3 -0.7 0.0 -0.2 -0.9 -0.4 -0.3 -0.7 0.1 -0.2 -0.3 -1.3 -1.1 -1.1 0.9 -0.7 -0.5 -0.4 -0.8 -0.8
Commuting to job workplace: Car/motor vehicle 0.4 0.4 3.2 -0.2 1.0 1.3 0.6 0.9 0.2 0.3 -0.1 0.2 0.2 0.6 0.7 1.5 1.5 0.7 0.1 0.2 0.6 0.4 0.8 -0.4 -0.9 0.3 0.0 0.4 1.0 -0.1 1.1 -0.3 0.3 0.0 0.6 0.3 0.3 0.3 0.5 0.2 0.1 -0.3 0.1 -0.7 -0.2 1.8 0.0 0.1 -0.3 0.1 -0.2
Illness, injury, bereavement, stress in last 2 years 0.8 1.0 2.6 0.6 1.4 1.3 0.8 1.4 1.2 1.3 1.4 0.9 1.1 1.2 1.5 1.1 1.4 0.8 1.3 1.1 1.0 1.3 0.8 0.8 0.0 1.4 0.0 1.2 1.4 0.6 0.5 -0.3 0.6 0.0 0.8 0.8 0.8 0.8 0.9 1.3 1.2 1.0 0.6 -0.0 0.3 1.6 0.9 1.0 0.8 0.9 0.6
Medication: Aspirin 0.3 0.4 2.7 0.4 1.3 -0.5 -0.9 0.1 -0.2 -0.4 -0.1 0.2 -0.0 0.7 0.4 1.6 1.3 1.3 0.4 -0.0 0.5 -0.1 0.5 1.0 0.2 1.0 0.0 0.2 -0.0 0.4 -0.6 0.8 0.4 0.0 0.2 0.6 0.4 0.3 0.5 -0.0 0.3 0.5 1.6 0.6 0.6 -0.2 0.7 0.5 0.3 0.7 0.5
Supplements: Vitamin C 0.7 0.8 7.1 0.3 1.0 1.1 1.6 0.4 0.6 0.8 0.4 0.5 0.4 0.3 -0.6 1.3 1.0 2.7 1.6 0.4 1.3 0.4 1.7 -0.3 0.7 0.6 0.0 0.4 0.9 0.4 1.9 0.7 0.7 0.0 1.1 0.5 0.5 0.6 0.5 0.5 0.3 0.2 0.4 -0.9 -0.2 2.0 0.2 0.3 -0.1 0.2 -0.2
Knee pain experienced in last month 0.5 0.8 5.0 -0.7 -1.9 0.5 1.4 -0.1 -0.2 0.5 -0.0 0.1 -0.4 -0.7 -1.5 -1.7 -1.0 0.7 0.4 -0.4 -0.8 -0.1 -0.5 -1.2 0.5 -0.6 0.0 -0.8 -0.9 -1.0 2.2 0.6 -0.2 0.0 0.3 -0.4 -0.0 -0.3 -0.9 -0.3 -0.6 -0.9 -0.7 -1.6 -1.0 1.6 -0.6 -0.5 -1.0 -0.6 -1.0
Hypertension (Self-reported) 0.3 0.8 4.2 0.1 1.1 -0.6 0.5 1.2 0.5 0.8 0.4 0.6 0.5 1.2 1.0 1.4 1.3 1.3 1.1 0.5 0.9 0.8 1.1 2.0 1.3 1.9 0.0 0.6 0.9 0.7 0.9 0.8 0.4 0.0 0.6 0.7 0.6 0.8 0.8 0.5 0.6 0.4 0.9 -0.3 0.2 1.7 0.7 0.6 0.2 0.6 0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.3 1.5 7.1 0.7 0.8 0.0 0.9 2.0 1.3 1.4 0.8 1.1 1.2 1.7 1.8 1.0 0.7 2.1 0.8 1.2 0.7 1.5 1.6 0.7 0.5 2.7 0.0 1.2 1.6 1.2 1.2 0.5 1.1 0.0 1.0 1.0 1.0 1.5 1.4 1.3 1.2 0.7 1.0 -0.1 0.6 2.4 1.1 1.1 0.7 1.1 0.7
Illnesses of father: Heart disease 0.4 0.6 5.4 -0.8 0.3 -0.0 0.8 -0.7 -0.6 -0.6 -0.6 -0.7 -0.6 -0.6 -1.1 -0.0 -0.3 2.3 -1.0 -0.6 -0.5 -0.5 -0.2 0.4 -0.0 0.6 0.0 -0.8 -1.0 -0.5 1.2 -0.5 -0.6 0.0 -0.3 -0.6 -0.6 -0.4 -0.7 -0.8 -0.9 -0.8 -0.5 -1.3 -1.2 0.7 -0.8 -0.8 -1.1 -0.8 -1.1
Illnesses of siblings: Diabetes 0.3 0.3 2.2 -0.7 -0.9 0.3 0.0 0.2 -0.6 -0.6 -1.0 -0.4 -0.5 0.3 1.0 -0.6 -0.9 -1.5 -0.6 -0.5 -0.9 -0.1 -0.4 -0.1 -0.9 -0.3 0.0 -0.7 0.6 -0.5 0.2 -0.5 0.1 0.0 -0.0 -0.2 -0.6 -0.4 -0.3 -0.6 -0.5 -0.5 -0.3 -0.2 -0.3 -0.5 -0.3 -0.5 -0.4 -0.5 -0.3
Smoking status: Previous 0.7 1.1 7.4 -0.7 -2.1 0.3 -0.2 -0.7 -1.6 -1.6 -0.3 -0.6 -1.3 -0.4 -0.3 -1.0 -2.7 0.4 0.9 -1.3 -2.2 -1.0 -0.7 -1.4 -1.2 -0.1 0.0 -1.8 -1.2 -1.1 -0.2 0.4 -0.9 0.0 -1.0 -0.3 -0.8 -0.4 -0.8 -1.3 -1.0 -1.0 1.1 -0.9 -0.7 0.3 -0.5 -0.7 -1.2 -0.4 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 1.9 3.9 7.0 -2.1 -1.8 -1.0 1.0 -2.4 -2.3 -2.0 -2.0 -2.1 -2.3 -2.6 -2.1 -1.6 -1.3 -1.5 -1.6 -2.3 -2.0 -2.1 -2.2 -0.7 0.5 -2.1 0.0 -2.3 -2.0 -2.3 1.2 -1.0 -2.4 0.0 -2.4 -2.4 -2.2 -2.3 -2.2 -2.2 -2.4 -2.5 -2.1 -1.9 -2.0 -1.2 -2.3 -2.4 -2.3 -2.3 -2.2
Whole body fat-free mass 0.8 4.5 16.6 -2.0 -3.9 -1.1 1.2 -1.6 -1.4 -1.4 -1.3 -1.4 -1.6 -2.7 -2.1 -4.1 -3.7 -1.6 -2.5 -1.6 -1.5 -1.2 -1.9 -3.5 1.2 -1.8 0.0 -2.1 -1.6 -2.1 0.5 -2.4 -2.8 0.0 -2.6 -2.8 -2.4 -1.8 -1.9 -1.6 -2.0 -1.9 -3.4 -1.2 -2.0 -2.7 -2.2 -2.1 -1.6 -2.3 -1.8
Leg fat-free mass (right) 0.8 4.4 14.9 -2.1 -3.6 -1.7 0.5 -1.6 -1.9 -2.0 -1.5 -1.6 -1.9 -2.3 -1.3 -3.8 -3.9 -1.3 -2.2 -1.8 -1.7 -1.6 -1.8 -2.3 1.3 -1.1 0.0 -2.4 -1.6 -2.1 -0.1 -1.9 -3.1 0.0 -3.2 -2.8 -2.6 -1.9 -2.0 -2.1 -2.1 -2.0 -2.4 -0.9 -1.8 -3.0 -2.0 -2.0 -1.7 -2.1 -1.6
Arm fat percentage (left) 0.2 0.7 4.6 0.2 -1.6 -0.8 -2.1 -0.5 -1.2 -1.7 -0.2 -0.2 -0.7 0.2 0.2 0.2 -1.4 0.5 0.7 -0.7 -1.4 -0.8 0.2 -0.2 -1.1 0.5 0.0 -1.0 -0.9 -0.1 -2.0 0.5 -0.1 0.0 -0.7 0.3 -0.3 -0.1 0.1 -1.0 -0.4 -0.4 2.0 0.7 0.7 -0.7 0.6 0.1 -0.2 0.5 0.4
Average weekly red wine intake 1.5 2.2 8.7 -1.0 -1.0 0.3 0.4 -2.1 -1.7 -1.7 -1.5 -1.2 -1.4 -2.2 -3.0 -1.9 -1.9 -0.9 -2.0 -1.4 -1.0 -1.4 -1.6 -1.9 0.8 -2.4 0.0 -1.8 -1.4 -1.1 0.0 -1.4 -1.0 0.0 -1.0 -1.2 -1.2 -1.4 -1.3 -1.7 -1.7 -1.6 -1.2 -0.3 -0.8 -2.6 -1.5 -1.5 -1.2 -1.6 -1.0
Handedness (chirality/laterality): Left-handed 0.6 0.7 2.4 -0.9 -1.5 -0.6 0.4 -0.5 -0.4 -0.4 -0.7 -0.7 -0.3 -1.3 -1.2 -1.2 -0.7 0.0 -1.5 -0.3 -0.1 -0.4 -0.7 -1.4 0.9 -1.0 0.0 -0.4 -0.7 -0.8 0.5 -1.3 -1.2 0.0 -0.9 -1.2 -0.7 -0.6 -0.3 -0.6 -0.8 -0.7 -1.6 -0.7 -1.1 -0.7 -0.9 -0.8 -0.7 -1.0 -0.8
Mood swings 0.6 1.0 4.1 1.5 -1.4 0.2 -0.7 0.8 0.8 0.6 0.9 1.3 0.9 0.8 -0.2 0.6 -0.6 0.4 0.8 0.9 -0.2 1.0 1.1 0.1 -0.4 -0.3 0.0 0.6 0.2 1.2 -0.5 0.4 1.8 0.0 1.6 1.6 1.5 1.5 1.4 0.8 1.0 0.7 1.8 0.2 0.8 2.0 1.3 1.2 0.7 1.3 0.8
Loneliness, isolation 0.2 0.3 2.0 -0.0 -1.0 -1.2 -0.0 -0.1 -0.4 -0.5 -1.0 -0.2 -0.3 -0.7 0.1 -1.2 -1.2 -0.1 -1.4 -0.3 0.6 -0.3 -0.7 -0.5 0.3 -0.6 0.0 -0.4 -0.2 -0.1 -0.4 0.5 -0.4 0.0 -0.5 -0.3 -0.3 -0.2 -0.1 -0.5 -0.3 -0.3 -0.1 0.5 0.0 -1.4 -0.2 -0.3 -0.0 -0.2 0.1
Long-standing illness, disability or infirmity 2.3 3.4 7.7 1.9 1.6 2.3 -2.2 1.5 1.4 1.0 1.7 1.8 1.8 2.0 0.6 2.2 0.8 1.7 2.2 1.8 0.9 1.8 1.7 1.6 0.4 2.1 0.0 1.7 1.1 2.1 -1.6 1.1 2.0 0.0 1.9 2.7 2.3 2.3 1.9 1.6 2.0 1.9 2.7 2.4 2.8 0.5 2.4 2.2 2.1 2.4 2.4
Ever had bowel cancer screening 1.4 1.7 4.9 1.6 -2.2 -0.3 -2.1 0.8 1.2 1.0 0.9 1.1 1.5 0.8 0.4 -0.7 -0.1 -0.7 1.3 1.5 -0.8 1.2 0.0 -1.0 -1.6 -1.2 0.0 1.2 0.3 1.2 -2.0 -1.0 1.4 0.0 1.1 1.7 1.8 1.3 1.8 1.5 1.7 1.7 1.5 1.4 1.5 0.4 1.6 1.6 1.7 1.6 1.6
Diabetes diagnosed by doctor 0.3 0.5 3.6 0.1 0.8 -0.1 -0.9 -0.1 -0.6 -0.7 -0.5 -0.3 -0.3 0.7 0.3 1.4 1.3 0.7 1.9 -0.3 -0.3 -0.4 0.3 1.2 -0.4 1.0 0.0 -0.2 -0.1 -0.0 -0.3 1.5 0.2 0.0 0.1 0.7 0.3 0.2 -0.2 -0.4 -0.0 -0.2 1.8 0.1 0.5 0.8 0.7 0.3 -0.1 0.5 0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.7 3.3 -0.8 -0.2 -0.3 1.3 -0.1 -0.3 -0.3 -1.0 -0.1 -0.3 -0.8 -0.7 -0.5 -0.7 -1.2 -1.7 -0.3 0.5 -0.1 -0.9 -1.0 1.5 -0.6 0.0 -0.4 0.7 -0.6 0.8 -1.5 -0.3 0.0 -0.1 -0.8 -0.7 -0.4 -0.5 -0.7 -0.9 -0.7 -1.8 -0.1 -0.6 -1.6 -1.1 -0.9 -0.5 -1.1 -0.6
Friendships satisfaction 1.1 1.4 3.4 0.8 1.8 -0.2 -0.6 1.5 1.5 1.3 0.9 0.8 1.5 1.5 1.8 1.5 1.6 -0.1 0.5 1.5 1.4 1.4 0.5 1.8 -0.4 1.4 0.0 1.8 0.5 1.3 -0.9 0.4 0.3 0.0 0.4 0.8 1.1 1.1 1.0 1.5 1.5 1.6 0.8 1.5 1.3 0.1 1.3 1.4 1.6 1.3 1.4
Qualifications: nursing, teaching 0.1 0.1 1.6 0.3 0.9 -0.3 0.3 0.3 0.1 0.3 0.2 0.3 0.1 -0.2 -0.0 0.4 0.4 0.2 -0.1 0.1 0.9 0.3 0.3 -0.1 0.9 0.3 0.0 0.2 0.1 -0.2 0.1 1.3 -0.2 0.0 -0.2 0.1 0.3 0.2 0.3 0.1 0.1 0.2 0.3 0.1 0.3 0.2 0.3 0.2 0.1 0.3 0.2
Commuting to job workplace: Walk 0.4 0.5 2.6 1.2 0.1 0.6 -0.3 0.0 0.5 0.6 1.0 0.8 0.4 0.1 -0.7 0.7 0.3 -0.8 1.3 0.4 -0.3 0.3 0.6 1.1 0.9 0.1 0.0 0.4 -0.0 0.8 -0.3 1.6 1.2 0.0 1.1 1.0 0.9 0.7 0.4 0.5 0.5 0.4 0.7 0.4 0.7 0.6 0.7 0.7 0.4 0.7 0.6
Eye problems/disorders: Cataract 1.0 1.2 7.2 1.0 0.2 1.8 -0.1 0.6 0.7 1.1 1.5 1.2 0.9 0.7 -0.6 2.1 2.0 -0.1 2.2 0.9 -0.1 0.9 2.0 -0.4 -0.1 1.0 0.0 1.0 0.0 0.9 0.4 1.4 0.7 0.0 0.7 0.8 0.9 1.4 1.1 0.8 0.7 0.4 1.1 -0.9 0.2 2.7 1.0 1.0 0.1 1.0 0.2
Mouth/teeth dental problems: Mouth ulcers 0.2 0.4 4.2 0.0 -0.2 -0.2 -0.4 -0.7 -0.1 -0.1 -0.1 -0.3 0.1 -0.9 -1.2 -0.5 -0.4 0.3 -1.8 0.1 0.9 -0.2 -0.4 -0.2 1.0 -0.3 0.0 0.1 -0.6 0.2 -0.7 -0.8 -0.7 0.0 -0.7 -0.5 -0.1 -0.2 0.1 -0.1 0.0 0.2 -0.7 0.8 0.2 -2.0 -0.3 -0.2 0.4 -0.2 0.3
Medication for cholesterol 0.1 0.2 1.1 -0.0 -0.1 -0.8 0.2 -1.1 -0.2 -0.2 0.3 -0.2 -0.4 -0.4 -0.5 -0.8 -0.2 -0.1 -0.3 -0.4 -0.8 -0.8 -0.3 -0.4 -0.6 -0.9 0.0 -0.3 -1.1 -0.2 -0.2 -0.2 -0.4 0.0 -0.7 -0.5 -0.4 -0.5 -0.3 -0.1 -0.2 -0.4 -0.4 -0.1 -0.4 -0.4 -0.3 -0.2 -0.1 -0.2 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 9.0 0.5 -1.1 1.1 -1.6 -0.3 -0.3 -0.3 0.2 -0.2 0.1 0.0 -0.8 1.7 1.7 3.0 2.0 0.1 -0.3 -0.2 -0.1 -1.2 -1.5 0.5 0.0 0.1 -1.0 -0.1 -0.6 0.7 0.4 0.0 0.4 0.9 0.6 0.2 0.0 -0.1 0.2 0.0 1.3 -0.1 0.2 0.8 0.6 0.3 0.0 0.5 0.2
Back pain experienced in last month 2.2 3.2 7.9 2.2 0.9 1.7 -1.6 1.8 1.3 1.2 1.5 1.9 1.8 2.0 1.3 1.4 1.3 -0.7 2.2 1.8 1.2 1.5 2.2 0.6 -1.3 1.5 0.0 1.6 1.8 2.2 -1.4 2.1 2.8 0.0 2.7 2.5 2.3 2.1 2.4 1.4 1.8 1.6 2.5 2.0 2.2 0.7 2.1 2.0 1.8 2.1 2.1
Mineral and other dietary supplements 0.2 0.3 1.6 0.5 0.1 -0.5 -0.8 -0.4 -0.6 -0.6 -0.4 0.1 -0.4 -0.4 -0.2 -0.4 -0.0 -1.1 -0.9 -0.4 0.1 -0.6 -0.7 1.3 0.9 -0.2 0.0 -0.4 -0.4 -0.2 -0.9 1.2 0.1 0.0 0.0 0.0 -0.1 -0.2 -0.6 -0.6 -0.4 -0.1 0.3 0.5 0.3 -0.8 0.0 -0.1 -0.2 0.0 0.1
Breast cancer (self-reported) 0.9 1.1 3.8 -1.4 -0.1 -1.9 1.1 -0.5 -0.8 -0.8 -1.3 -0.9 -0.9 -0.7 0.3 -1.2 -0.6 0.8 -1.9 -0.9 -0.1 -0.7 -1.2 0.3 0.4 0.7 0.0 -1.0 -0.7 -0.9 0.9 -0.9 -1.4 0.0 -1.4 -1.5 -1.4 -1.1 -1.3 -0.9 -0.9 -1.0 -1.7 -0.6 -1.3 -1.3 -1.3 -1.2 -0.8 -1.3 -1.0
Asthma (self-reported) 0.1 0.3 1.7 0.4 -1.0 0.9 -0.7 0.3 -0.0 0.1 -0.1 0.3 0.1 0.0 -0.1 -0.1 -0.7 -0.2 -0.3 0.1 -0.5 0.0 -0.6 -0.7 -1.1 -0.8 0.0 -0.1 -0.4 -0.3 0.2 1.3 0.5 0.0 0.8 0.5 0.4 0.2 -0.1 -0.1 0.1 -0.2 0.9 -0.4 -0.2 1.3 0.3 0.2 -0.2 0.3 -0.1
Osteoporosis (self-reported) 0.4 0.5 3.7 0.6 0.7 -0.7 -1.6 -0.1 0.0 -0.3 0.6 0.1 0.2 1.0 1.2 0.9 0.2 0.1 0.9 0.2 -1.1 -0.3 0.3 0.8 -1.9 -0.3 0.0 0.3 -0.1 0.3 -1.2 0.6 0.2 0.0 -0.1 0.8 0.5 0.1 0.3 0.2 0.5 0.3 1.9 0.3 0.7 0.8 1.0 0.7 0.3 0.9 0.6
Osteoarthritis (self-reported) 0.3 0.3 2.7 -0.4 -0.6 0.4 1.1 0.1 -0.2 0.2 0.5 -0.2 -0.3 -0.4 -0.5 0.2 -0.6 1.7 0.2 -0.3 0.1 0.1 0.8 -0.8 -0.0 0.4 0.0 -0.3 -0.2 -0.3 1.1 0.1 -0.4 0.0 -0.2 -0.4 -0.3 -0.1 0.1 -0.1 -0.3 -0.6 -0.4 -1.3 -0.9 1.4 -0.4 -0.5 -0.7 -0.4 -0.8
Medication: Aspirin 0.3 0.3 2.8 0.1 1.2 -0.2 -0.9 -0.5 -0.7 -1.0 -0.4 -0.3 -0.5 0.4 0.0 1.3 1.0 1.3 0.3 -0.5 -0.0 -0.6 0.2 1.0 -0.1 0.7 0.0 -0.3 -0.5 0.0 -0.7 0.7 0.1 0.0 -0.1 0.4 -0.0 -0.1 0.1 -0.5 -0.1 0.2 1.7 0.4 0.4 -0.4 0.4 0.1 -0.1 0.4 0.2
Medication: Gliclazide 0.3 0.3 2.2 0.6 0.6 -0.6 -0.8 -0.0 0.4 0.5 0.6 0.4 0.5 0.3 -0.4 0.6 0.9 1.5 1.2 0.5 0.3 0.3 0.8 0.3 0.3 0.3 0.0 0.6 -0.1 0.7 -0.1 0.3 -0.0 0.0 -0.1 0.5 0.6 0.5 0.8 0.6 0.7 0.3 0.9 -0.1 0.3 1.0 0.7 0.6 0.4 0.7 0.4
Illnesses of father: None of the above (group 1) 1.1 1.3 6.3 -1.1 -2.5 -0.8 0.6 -0.9 -1.1 -0.9 -1.2 -1.2 -1.2 -1.4 -0.6 -1.8 -1.3 -2.0 -0.5 -1.2 -1.2 -1.1 -1.4 -0.8 0.4 -1.5 0.0 -1.3 -0.6 -1.1 0.3 -0.5 -1.3 0.0 -1.3 -1.3 -1.2 -1.2 -1.0 -1.1 -1.1 -1.2 -1.1 -0.7 -0.9 -1.1 -1.3 -1.2 -1.0 -1.3 -1.0
Smoking status: Current 0.9 1.4 2.9 1.5 0.3 1.4 -0.4 1.3 1.4 1.5 1.2 1.2 1.6 0.6 0.3 0.6 1.3 -0.5 0.9 1.6 1.7 1.4 0.8 -0.3 0.7 0.6 0.0 1.6 1.3 1.3 -0.5 0.8 1.3 0.0 1.5 1.3 1.7 1.4 1.3 1.5 1.3 1.2 0.4 1.4 1.4 0.0 1.4 1.5 1.4 1.4 1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.8 1.7 5.1 1.4 1.1 1.8 -0.9 1.6 1.0 0.9 0.8 1.3 1.3 1.5 1.5 2.3 1.6 0.1 1.1 1.3 1.4 1.1 1.6 0.7 -0.4 1.5 0.0 1.4 1.7 1.5 -0.6 1.4 1.7 0.0 1.6 1.7 1.3 1.4 1.1 0.9 1.2 1.3 1.6 1.1 1.4 0.8 1.3 1.4 1.1 1.4 1.2
Whole body water mass 0.8 4.4 16.6 -1.9 -3.9 -1.0 1.2 -1.5 -1.4 -1.3 -1.2 -1.3 -1.5 -2.7 -2.1 -4.1 -3.7 -1.5 -2.4 -1.5 -1.4 -1.2 -1.8 -3.5 1.2 -1.8 0.0 -2.1 -1.5 -2.1 0.5 -2.4 -2.7 0.0 -2.6 -2.8 -2.3 -1.7 -1.9 -1.6 -2.0 -1.9 -3.3 -1.2 -2.0 -2.6 -2.2 -2.1 -1.6 -2.2 -1.8
Leg predicted mass (right) 0.8 4.3 14.8 -2.1 -3.5 -1.7 0.4 -1.6 -1.9 -2.0 -1.5 -1.6 -1.8 -2.3 -1.3 -3.8 -3.9 -1.3 -2.2 -1.8 -1.7 -1.6 -1.7 -2.2 1.3 -1.1 0.0 -2.4 -1.6 -2.0 -0.2 -1.9 -3.1 0.0 -3.2 -2.7 -2.6 -1.8 -1.9 -2.0 -2.1 -2.0 -2.4 -0.9 -1.7 -3.0 -2.0 -2.0 -1.7 -2.1 -1.6
Arm fat mass (left) 0.2 0.8 5.3 -0.1 -2.3 -0.9 -1.8 -0.6 -1.2 -1.6 -0.3 -0.3 -0.8 -0.2 -0.1 -0.9 -2.2 -0.0 -0.1 -0.8 -1.3 -0.8 -0.1 -0.9 -0.7 0.1 0.0 -1.2 -0.9 -0.3 -1.8 -0.3 -0.6 0.0 -1.1 -0.3 -0.7 -0.3 -0.1 -1.1 -0.6 -0.6 0.9 0.5 0.3 -1.3 0.1 -0.2 -0.3 0.0 0.1
Number of self-reported non-cancer illnesses 0.6 1.0 12.6 0.4 0.8 -0.5 -0.8 1.2 0.1 -0.1 0.2 0.1 0.4 1.4 1.4 1.5 -0.1 3.5 1.0 0.4 0.7 0.5 1.0 1.4 -0.0 2.3 0.0 0.1 0.3 0.7 0.1 0.6 0.6 0.0 0.4 1.1 0.6 0.8 1.1 0.2 0.6 0.4 2.1 0.4 0.9 1.2 1.2 0.9 0.4 1.1 0.7
Average weekly champagne plus white wine intake 1.3 1.8 6.2 1.8 0.1 1.7 -1.4 0.7 1.2 0.6 0.8 1.3 1.0 0.8 0.5 0.9 0.8 -1.8 1.1 1.0 1.0 1.3 0.7 -0.7 0.6 -1.0 0.0 1.2 2.3 1.4 -2.1 -0.8 2.0 0.0 1.8 1.8 1.4 1.1 1.6 1.1 1.3 1.5 0.5 2.5 2.0 -1.9 1.2 1.2 1.9 1.2 1.9
Miserableness 0.2 0.4 2.5 0.0 -1.4 -0.2 -0.8 -1.0 -0.6 -1.0 -0.1 -0.1 -0.8 -1.0 -1.2 -0.5 -1.4 -0.4 -1.2 -0.8 -0.6 -0.5 -0.5 -0.7 0.1 -1.6 0.0 -0.8 -0.8 -0.4 -0.8 -0.7 0.1 0.0 -0.1 0.1 0.0 -0.2 0.1 -0.6 -0.4 -0.5 0.1 0.3 0.1 -1.0 -0.1 -0.3 -0.2 -0.2 0.0
Guilty feelings 0.1 0.2 1.7 0.1 -0.5 -0.1 0.0 -0.1 0.2 -0.2 -0.1 0.4 0.0 0.3 0.4 -0.0 -0.2 -0.4 -0.8 0.0 0.4 0.0 0.4 1.3 0.3 -0.0 0.0 0.1 0.3 0.9 -0.6 -0.4 0.2 0.0 0.0 0.1 0.1 0.2 0.4 0.1 0.3 0.6 0.1 1.1 0.5 -1.2 0.2 0.2 0.6 0.2 0.6
Wears glasses or contact lenses 1.6 1.9 4.3 1.9 1.0 0.4 -1.5 0.9 1.1 0.7 1.3 1.8 1.3 1.4 1.0 1.2 1.1 0.9 0.9 1.3 1.2 0.7 1.9 0.0 -0.9 0.9 0.0 1.4 0.9 1.5 -2.1 1.2 1.2 0.0 1.0 1.6 1.6 1.6 1.6 1.2 1.5 1.6 1.8 2.0 2.0 -0.2 1.9 1.8 1.7 1.9 1.9
Ever taken oral contraceptive pill 0.5 0.6 1.7 1.1 -0.0 1.0 -0.1 0.5 0.7 0.6 0.6 1.1 0.9 0.4 -0.2 1.1 0.6 0.2 1.0 0.9 0.8 0.7 0.6 0.1 -0.2 0.1 0.0 0.9 0.9 0.7 -0.3 0.3 1.2 0.0 1.3 1.1 1.2 1.0 0.5 0.7 0.6 0.7 0.6 0.5 0.9 0.9 0.8 0.8 0.5 0.8 0.7
Hearing aid user 0.8 0.9 6.4 0.5 2.1 0.8 -0.1 -0.0 0.1 0.3 0.8 0.1 0.4 0.6 -0.6 2.0 2.1 2.2 2.5 0.4 0.2 0.0 0.7 0.8 0.1 0.8 0.0 0.5 0.0 0.2 0.8 1.6 0.6 0.0 0.7 1.0 0.9 0.4 0.3 0.3 0.5 0.3 1.7 -0.3 0.5 1.9 0.8 0.6 0.1 0.8 0.3
Mother’s age at death 0.3 0.4 5.2 -0.8 0.8 1.5 0.8 -0.0 0.1 -0.1 -0.1 -0.3 -0.2 -0.2 -0.0 0.4 -0.7 -0.0 -0.6 -0.2 0.7 0.2 -0.2 -0.9 0.9 0.1 0.0 -0.2 0.7 0.0 0.1 -1.0 -0.1 0.0 0.0 -0.4 -0.5 -0.2 -0.6 -0.2 -0.1 0.4 -1.2 0.9 0.3 -2.3 -0.6 -0.4 0.3 -0.5 0.2
Financial situation satisfaction 0.5 0.6 5.6 -0.3 -0.2 -1.1 0.0 0.2 -0.7 -0.9 -0.6 -0.8 -0.5 0.6 1.3 0.5 0.1 2.4 0.3 -0.5 -0.7 -0.6 0.1 0.8 -1.4 1.1 0.0 -0.5 -0.7 -0.5 0.6 0.4 -0.4 0.0 -0.6 0.0 -0.5 -0.1 -0.5 -0.6 -0.4 -0.5 1.5 -1.2 -0.7 1.8 0.1 -0.1 -0.8 0.0 -0.7
Tinnitus: Yes, now most or all of the time 1.5 1.7 5.1 1.6 1.5 2.2 -2.2 -0.1 0.8 0.5 1.1 0.5 0.9 0.6 -0.7 0.8 0.3 1.4 1.2 0.9 0.9 0.9 1.1 0.4 -0.5 0.1 0.0 0.9 0.4 1.6 -2.2 0.1 1.3 0.0 1.1 1.9 1.7 1.1 1.6 1.1 1.6 1.6 1.9 2.1 2.0 -0.6 1.7 1.4 1.8 1.7 1.9
Commuting to job workplace: Public transport 0.2 0.2 1.3 0.4 -0.2 -1.2 -0.3 0.1 0.2 0.0 0.1 -0.1 0.0 0.0 0.7 -0.1 -0.2 0.4 -0.7 0.0 0.6 0.1 0.1 1.0 1.0 -0.0 0.0 0.1 0.6 0.5 -0.6 -0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.4 0.5 0.2 0.5 0.5 -0.9 0.3 0.2 0.4 0.3 0.4
Eye problems/disorders: Glaucoma 0.1 0.1 1.6 -0.1 0.4 1.0 0.2 -0.1 0.1 0.4 -0.1 -0.0 0.3 0.0 -0.5 -0.2 -0.0 -0.6 -0.0 0.3 -0.1 -0.0 -0.3 -0.0 -1.3 0.3 0.0 0.2 -0.8 -0.1 0.3 1.0 0.2 0.0 0.5 0.1 0.3 0.1 -0.6 0.1 0.1 0.2 0.2 0.0 0.2 0.3 0.1 0.2 0.1 0.1 0.1
Medication: Blood pressure 0.1 0.3 1.5 -0.1 -1.0 0.3 -0.9 0.7 -0.5 -0.7 -0.2 -0.1 -0.1 0.7 1.0 0.4 -0.4 0.3 0.7 -0.1 -0.6 0.3 0.3 1.0 -0.1 0.9 0.0 -0.3 0.5 -0.0 -0.7 -0.4 0.4 0.0 0.3 0.6 0.1 0.4 0.2 -0.3 -0.0 -0.1 1.2 -0.0 0.2 0.5 0.3 0.2 -0.2 0.4 0.1
Pain type(s) experienced in last month: Hip pain 0.5 0.6 6.1 0.9 0.5 -0.2 -0.9 0.1 -0.1 0.0 -0.1 0.3 0.1 0.4 0.3 0.8 -0.2 1.0 0.7 0.1 0.3 -0.2 -0.1 1.3 -0.6 0.6 0.0 0.1 -0.2 0.5 -0.8 2.5 0.9 0.0 0.7 1.3 1.0 0.3 0.4 0.1 0.6 0.2 1.8 0.7 0.9 0.6 1.0 0.8 0.5 1.1 0.8
Supplements: Fish oil (including cod liver oil) 0.4 0.6 1.6 0.3 0.3 1.2 0.4 0.9 1.0 1.0 0.6 0.5 0.9 0.7 0.3 1.2 1.0 0.1 1.1 0.9 0.2 1.1 1.2 -0.6 -0.3 0.6 0.0 1.0 1.2 0.7 0.6 -0.1 0.5 0.0 0.7 0.7 0.8 0.8 1.1 1.0 0.8 0.4 0.0 -0.2 0.2 1.2 0.6 0.6 0.5 0.5 0.4
High cholesterol (Self-reported) 0.5 1.0 7.9 0.5 0.4 0.3 -0.1 1.1 0.1 0.3 0.3 0.3 0.3 1.1 1.2 1.8 1.1 2.1 1.7 0.3 0.1 0.4 0.9 1.1 -0.7 1.7 0.0 0.3 -0.3 0.2 0.8 2.2 0.6 0.0 0.6 0.9 0.6 0.7 0.4 0.1 0.4 0.2 2.1 -0.7 0.2 2.8 0.9 0.7 -0.2 0.9 0.0
Medication: Bendroflumethiazide 0.4 0.6 3.4 -0.6 -0.1 -0.6 0.8 0.2 -0.9 -0.6 -0.5 -0.6 -0.8 0.1 0.5 0.4 -0.1 1.8 1.3 -0.8 -0.7 -0.5 -0.1 0.8 -0.3 1.1 0.0 -0.9 -0.7 -0.8 1.2 1.5 -0.4 0.0 -0.3 -0.2 -0.4 -0.4 -0.7 -0.8 -0.6 -0.7 1.1 -1.4 -0.7 1.8 -0.2 -0.4 -1.1 -0.2 -0.9
Medication: Paracetamol 0.7 1.1 7.6 1.3 -0.1 1.5 0.1 0.8 0.6 0.9 0.5 1.2 0.9 0.5 -1.1 1.0 1.0 1.1 1.9 0.9 0.5 0.8 1.0 0.2 0.4 0.3 0.0 0.6 0.6 0.9 1.1 1.6 1.9 0.0 2.2 1.5 1.6 1.3 0.9 0.5 0.5 0.4 1.6 -0.7 0.3 2.8 0.9 0.9 -0.0 0.9 0.1
Medication: Lisinopril 0.3 0.5 2.4 0.3 0.6 0.8 -0.9 0.1 0.6 0.3 0.9 0.5 0.5 0.5 -0.1 1.5 0.0 0.7 0.5 0.5 0.5 0.6 1.1 0.8 1.0 0.6 0.0 0.6 0.9 1.0 -0.7 -0.8 0.4 0.0 0.5 0.7 0.5 0.7 0.6 0.6 0.7 0.8 0.3 0.8 0.8 -0.4 0.6 0.6 0.8 0.6 0.7
Medication: Atorvastatin 0.4 0.5 2.8 -0.6 1.3 0.4 0.5 -0.8 -0.9 -1.0 -0.8 -1.0 -0.8 -0.4 -1.2 1.2 -0.4 1.7 0.1 -0.8 -0.2 -0.8 -0.5 0.3 1.4 0.8 0.0 -0.8 -0.1 -0.5 0.3 0.1 -0.4 0.0 -0.4 0.1 -0.4 -0.3 -0.7 -0.8 -0.7 -0.6 0.5 -0.0 0.1 -0.2 -0.4 -0.4 -0.6 -0.3 -0.3
Illnesses of father: High blood pressure 0.0 0.1 0.4 -0.1 0.2 -0.4 -0.3 0.4 -0.1 -0.2 -0.2 0.0 0.1 0.2 0.6 0.6 0.4 0.4 -0.3 0.1 0.4 0.1 -0.1 -0.0 -0.4 -0.1 0.0 0.2 0.1 -0.5 -0.0 -0.1 -0.1 0.0 -0.1 0.1 -0.1 0.1 -0.2 -0.0 -0.1 -0.1 -0.2 -0.3 -0.2 0.2 0.1 0.1 -0.1 0.1 -0.1
Alcohol drinker status: Never 0.7 0.9 3.0 1.2 1.5 0.1 -1.2 0.2 0.6 0.1 0.8 0.4 0.8 1.1 1.1 0.2 0.3 -1.0 0.5 0.8 0.1 0.3 0.4 1.4 -1.3 0.6 0.0 0.8 0.2 1.3 -1.5 -0.2 1.0 0.0 0.5 1.1 0.8 0.4 0.9 0.7 1.1 1.3 1.7 1.6 1.6 -0.3 1.2 1.1 1.2 1.2 1.4
Ever smoked 2.0 3.4 6.6 2.3 -0.5 1.7 -1.5 2.0 2.1 2.0 2.6 2.3 2.2 1.8 1.1 0.7 -0.0 0.2 1.8 2.2 1.3 2.2 2.4 -0.5 0.2 1.6 0.0 2.0 1.7 2.3 -1.8 1.3 1.5 0.0 1.5 2.0 2.2 2.6 2.5 2.3 2.2 2.3 1.6 1.9 2.1 0.9 2.4 2.4 2.2 2.4 2.3
Basal metabolic rate 0.8 4.3 15.7 -1.9 -4.0 -1.3 0.7 -1.6 -1.6 -1.6 -1.3 -1.4 -1.7 -2.5 -1.9 -3.8 -3.7 -1.5 -2.1 -1.7 -1.8 -1.3 -1.8 -3.1 0.9 -1.7 0.0 -2.2 -1.7 -2.0 0.1 -2.3 -2.7 0.0 -2.7 -2.6 -2.3 -1.8 -1.9 -1.8 -2.1 -1.9 -2.8 -1.1 -1.8 -2.6 -2.1 -2.0 -1.7 -2.1 -1.7
Leg fat percentage (left) 0.2 0.7 3.7 -0.2 -1.9 -0.3 -1.6 -0.6 -1.2 -1.7 -0.4 -0.6 -0.9 0.1 0.0 0.1 -1.6 1.1 0.4 -0.9 -1.4 -0.8 0.0 -0.7 -1.3 0.4 0.0 -1.2 -0.8 -0.4 -1.3 -0.6 -0.2 0.0 -0.7 0.1 -0.6 -0.3 -0.2 -1.1 -0.7 -0.8 1.1 0.1 0.0 -0.4 0.0 -0.3 -0.6 -0.1 -0.2
Arm fat-free mass (left) 0.9 4.6 15.4 -2.0 -3.7 -0.8 1.1 -1.8 -1.6 -1.6 -1.2 -1.4 -1.7 -2.7 -2.1 -3.9 -3.7 -1.3 -2.7 -1.7 -1.5 -1.3 -1.9 -3.4 0.8 -1.9 0.0 -2.2 -1.6 -2.1 0.4 -2.7 -2.7 0.0 -2.6 -2.7 -2.4 -1.9 -1.9 -1.7 -2.1 -1.9 -3.2 -1.2 -2.0 -2.7 -2.3 -2.2 -1.7 -2.3 -1.8
Number of operations (self-reported) 2.6 3.9 7.0 -2.2 -0.3 -1.5 0.8 -2.6 -2.4 -2.6 -2.4 -2.4 -2.4 -2.3 -1.8 -1.7 -2.3 2.3 -1.8 -2.4 -1.2 -2.6 -2.2 -1.9 -0.1 -1.2 0.0 -2.7 -2.3 -2.2 0.6 -1.1 -2.1 0.0 -2.3 -2.0 -2.3 -2.3 -1.9 -2.5 -2.2 -2.1 -1.0 -0.9 -1.6 -2.6 -1.9 -2.1 -1.8 -2.0 -1.7
Average weekly beer plus cider intake 0.9 1.3 6.6 1.3 -0.2 0.6 -2.6 1.4 0.2 -0.0 0.4 0.9 0.7 1.6 2.1 0.9 0.3 -1.2 1.2 0.7 0.0 0.6 1.1 0.9 -1.7 1.1 0.0 0.6 1.0 0.8 -1.8 1.5 1.4 0.0 0.9 1.5 1.0 1.2 1.1 0.4 0.8 1.0 2.3 0.9 1.3 0.8 1.4 1.2 0.7 1.4 1.1
Irritability 0.3 0.5 2.4 0.6 -0.3 1.0 -0.4 0.6 0.1 -0.1 0.2 1.0 0.2 0.7 1.1 0.7 0.3 -1.3 0.5 0.3 0.7 0.3 0.3 -0.5 -0.5 0.2 0.0 0.3 0.7 0.4 -1.0 1.5 0.8 0.0 0.7 0.9 0.6 0.7 0.6 0.2 0.5 0.7 1.2 1.2 0.7 -0.9 0.7 0.6 0.8 0.8 0.9
Risk taking 1.3 1.8 7.7 -1.4 -2.8 -1.7 0.2 -1.0 -1.1 -1.4 -1.1 -0.7 -1.3 -0.8 -0.3 -2.0 -2.1 -1.4 -1.2 -1.3 -2.8 -1.0 -1.2 -0.7 -1.1 -2.0 0.0 -1.6 -1.0 -1.6 0.2 -2.1 -0.9 0.0 -1.0 -1.1 -1.2 -1.1 -1.1 -1.3 -1.4 -1.3 -0.8 -1.7 -1.3 0.4 -1.3 -1.3 -1.6 -1.3 -1.5
Ever had prostate specific antigen (PSA) test 0.2 0.2 2.0 -0.1 -0.1 1.4 0.8 0.3 0.2 0.1 -0.7 -0.3 -0.0 -0.2 -0.3 0.0 0.0 -0.5 -0.1 -0.0 0.4 0.3 -0.2 -0.8 0.8 -0.3 0.0 -0.0 1.2 0.4 0.8 -0.9 0.3 0.0 0.4 -0.0 -0.2 -0.0 0.1 0.0 -0.2 -0.2 -1.0 -0.3 -0.6 -0.5 -0.5 -0.3 -0.2 -0.4 -0.3
Fractured/broken bones in last 5 years 0.1 0.1 1.2 0.1 -0.4 0.1 -0.8 -0.3 -0.1 -0.4 -0.3 -0.1 -0.2 0.1 0.2 -0.5 -0.1 -0.5 -0.3 -0.2 -0.7 -0.3 -0.1 -0.2 -0.9 -0.2 0.0 -0.2 -0.1 0.1 -0.9 -0.7 0.3 0.0 0.1 0.2 0.0 -0.2 -0.0 -0.1 -0.1 -0.1 -0.1 0.5 0.2 -1.1 0.0 0.0 0.2 0.0 0.3
Age started oral contraceptive pill 1.8 2.3 5.4 1.6 -0.3 0.2 -1.4 1.9 1.4 0.9 2.1 1.4 1.6 2.0 2.1 0.6 -0.7 1.0 0.7 1.6 0.9 1.8 2.1 0.6 0.2 1.1 0.0 1.5 1.9 1.6 -1.9 -1.0 1.4 0.0 1.1 1.9 1.4 1.9 2.3 1.6 1.9 1.9 1.8 1.7 1.7 0.5 1.9 1.8 1.9 1.9 1.9
Diastolic blood pressure, automated reading 1.8 5.6 9.9 -2.4 -1.3 -2.7 0.5 -3.0 -3.1 -3.0 -2.3 -2.6 -3.1 -2.4 -1.6 -1.9 -1.9 -0.6 -2.1 -3.1 -3.0 -3.1 -2.7 0.1 -0.9 -2.0 0.0 -3.1 -3.1 -2.9 0.5 -0.8 -2.0 0.0 -2.6 -2.3 -2.8 -2.9 -3.0 -2.9 -2.9 -3.0 -1.6 -2.0 -2.3 -1.3 -2.6 -2.8 -2.8 -2.6 -2.5
Ever depressed for a whole week 1.0 1.3 3.7 -1.3 -0.5 -1.8 0.4 -1.7 -1.3 -1.3 -0.8 -1.4 -1.5 -1.0 -0.5 -0.5 -0.7 -0.3 -1.6 -1.5 -1.6 -1.5 -1.0 0.9 -0.5 0.0 0.0 -1.3 -1.9 -0.9 0.2 0.3 -1.5 0.0 -1.8 -1.3 -1.3 -1.3 -1.1 -1.2 -1.0 -1.2 -0.3 -1.0 -1.1 -0.2 -0.9 -1.1 -1.1 -0.9 -1.0
Unable to work because of sickness or disability 0.3 0.3 1.4 -1.0 0.5 -0.0 0.6 -0.5 -0.6 -0.5 -0.7 -0.7 -0.6 -0.4 -0.4 0.4 0.4 0.8 -0.0 -0.6 -0.1 -0.5 -0.8 1.2 0.3 0.0 0.0 -0.5 -0.3 -0.8 1.1 -0.3 -0.2 0.0 -0.1 -0.1 -0.4 -0.4 -1.0 -0.5 -0.6 -0.7 -0.6 -0.7 -0.6 0.3 -0.7 -0.7 -0.7 -0.7 -0.7
Commuting to job workplace: Cycle 0.3 0.4 3.5 0.6 0.2 0.1 -1.0 -0.1 0.1 0.1 0.4 0.6 0.2 0.2 0.3 -1.1 -0.5 -1.9 -0.3 0.2 0.0 -0.1 -0.5 0.4 0.1 0.5 0.0 0.1 -0.5 0.4 -1.4 1.0 0.2 0.0 -0.1 0.1 0.1 0.2 0.1 0.1 0.5 1.0 0.5 1.4 0.7 -1.5 0.6 0.5 0.8 0.5 0.8
Myopia 0.5 0.7 2.7 1.1 0.3 -0.4 -0.6 0.8 0.7 0.6 0.7 0.7 0.8 0.8 1.2 1.6 1.6 0.4 0.2 0.8 0.8 0.5 1.2 0.1 -0.1 0.8 0.0 1.1 0.6 0.8 -0.5 0.8 0.9 0.0 0.5 0.9 0.8 0.9 1.6 0.8 1.1 0.8 1.2 0.4 0.3 0.8 1.1 1.0 0.9 1.1 0.8
Vascular/heart problems diagnosed by doctor 0.3 0.9 6.7 -0.1 -1.7 0.2 0.3 -0.7 -0.1 0.0 -0.1 -0.4 -0.2 -1.3 -1.0 -2.3 -1.4 -1.8 -1.3 -0.2 -0.9 -0.4 -1.1 -2.6 -1.2 -2.0 0.0 -0.3 -0.9 -0.8 -0.2 -0.5 -0.4 0.0 -0.4 -0.9 -0.5 -0.7 -0.8 -0.2 -0.4 -0.4 -1.5 -0.3 -0.7 -0.9 -0.7 -0.5 -0.3 -0.7 -0.5
Cholesterol lowering medication 0.8 1.2 3.5 1.0 -0.0 1.6 -0.7 1.3 1.0 1.1 1.1 1.2 1.2 1.2 0.6 1.0 1.3 -0.6 1.9 1.2 -0.0 1.3 1.2 0.2 -0.7 1.1 0.0 1.1 0.8 0.9 -0.4 0.9 1.5 0.0 1.6 1.3 1.4 1.4 1.1 1.1 1.2 1.2 1.3 0.5 0.9 1.2 1.3 1.1 0.9 1.1 0.9
Medication: Omeprazole (e.g. Zanprol) 0.5 0.7 6.0 0.4 -1.6 -1.3 -0.1 1.2 0.8 0.7 0.8 0.7 0.7 1.2 2.1 0.3 0.2 -0.0 1.0 0.6 -1.2 0.5 0.9 0.1 -1.4 0.4 0.0 0.7 0.5 0.1 0.4 -0.1 0.5 0.0 0.1 0.4 0.3 0.5 0.6 0.9 0.6 0.0 0.4 -0.8 -0.3 2.5 0.5 0.6 0.1 0.6 0.1
Pain experienced in last month 0.4 0.7 3.0 -0.7 -0.3 -1.7 0.0 -0.5 -0.6 -0.7 -0.5 -0.8 -0.8 -0.2 1.0 0.6 0.8 0.8 -0.5 -0.8 -0.6 -0.9 -0.6 0.3 -0.9 -0.3 0.0 -0.4 -1.0 -1.3 0.2 -0.8 -1.4 0.0 -1.6 -1.1 -1.3 -1.1 -0.8 -0.6 -0.6 -0.7 -0.6 -1.2 -1.1 0.7 -0.7 -0.8 -0.9 -0.8 -1.0
Supplements: Calcium 1.9 2.1 4.8 1.6 0.1 2.2 -1.1 1.0 1.6 1.3 1.9 1.7 1.5 1.4 0.6 1.1 0.8 0.5 1.5 1.5 0.8 1.4 1.9 -0.8 -1.8 -0.0 0.0 1.6 1.5 1.5 -1.4 -0.8 1.9 0.0 1.9 1.8 1.8 1.7 2.1 1.7 1.8 1.8 1.3 1.3 1.6 1.0 1.5 1.6 1.7 1.6 1.5
Basal cell carcinoma (self-reported) 0.1 0.2 1.9 0.1 0.1 0.4 0.1 0.2 -0.3 -0.2 -0.1 -0.4 -0.1 0.5 0.3 -0.1 -0.2 -0.5 1.4 -0.1 -0.7 0.1 -0.4 0.9 -0.6 0.1 0.0 -0.3 0.5 -0.1 0.1 0.0 0.8 0.0 0.7 0.6 0.2 0.0 -0.4 -0.1 -0.2 -0.3 0.2 -0.4 -0.1 0.9 -0.1 -0.0 -0.3 -0.0 -0.2
Heart attack/myocardial infarction (self-reported) 0.9 1.1 12.5 0.6 2.5 1.6 -0.1 0.3 -0.4 -0.8 0.3 0.2 -0.2 1.0 0.5 3.5 1.1 2.3 1.0 -0.2 1.3 0.3 1.0 1.3 0.8 2.0 0.0 -0.0 1.3 0.7 0.0 0.7 1.2 0.0 1.1 1.3 0.3 0.8 0.4 -0.1 0.3 0.3 1.7 0.8 1.0 0.0 0.6 0.4 0.3 0.6 0.6
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 6.5 0.2 -1.0 -0.7 -0.4 0.1 1.2 1.0 0.2 0.2 0.9 -0.0 -0.1 -2.0 -1.3 -1.7 -0.6 0.9 0.0 1.0 -0.6 -0.7 -0.2 -0.8 0.0 0.8 0.7 1.1 -1.1 -2.5 0.3 0.0 0.4 0.2 0.6 0.1 0.5 1.0 0.9 1.0 -1.4 1.6 1.2 -1.9 0.2 0.4 1.3 0.1 1.1
Heart disease (siblings) 1.0 1.2 4.0 0.7 0.5 0.9 0.2 1.6 1.9 1.9 1.1 1.6 1.6 1.6 0.7 0.0 0.2 0.3 0.2 1.6 0.3 1.6 1.4 0.9 0.9 1.7 0.0 1.4 1.5 1.5 0.6 -0.4 0.6 0.0 0.8 0.8 1.1 1.4 1.1 1.6 1.3 1.1 -0.0 0.1 0.5 2.0 0.9 1.2 1.0 0.9 0.7
Alcohol drinker status: Previous 0.3 0.3 1.9 0.1 0.4 -0.0 0.6 1.1 0.6 0.6 0.6 0.7 0.6 0.9 1.1 0.4 0.1 1.0 -0.2 0.5 0.6 0.7 0.7 0.5 0.5 1.4 0.0 0.5 0.7 0.3 0.3 -0.2 -0.0 0.0 0.0 -0.0 0.2 0.7 0.5 0.5 0.4 0.2 -0.3 0.1 0.2 0.5 0.2 0.3 0.3 0.3 0.3
Pack years of smoking 0.9 1.4 3.3 1.4 0.5 0.2 0.2 1.8 1.3 1.5 0.9 1.4 1.4 1.2 1.3 0.0 0.4 -0.7 0.7 1.4 1.6 1.4 1.1 1.4 0.9 0.7 0.0 1.2 1.7 1.2 -0.1 1.7 1.4 0.0 1.7 1.2 1.5 1.4 1.1 1.2 1.2 1.3 1.2 0.9 1.2 1.1 1.2 1.3 1.1 1.3 1.1
Impedance of whole body 0.2 0.9 4.1 -0.0 1.1 -1.0 -1.2 -1.2 -1.1 -1.3 -0.5 -0.6 -0.8 0.3 0.3 2.0 2.0 -1.2 1.3 -0.8 -1.8 -1.3 -0.3 1.9 -2.0 -1.3 0.0 -0.4 -0.9 -0.4 -0.8 0.9 0.2 0.0 -0.4 0.4 -0.1 -0.5 -0.2 -0.7 -0.4 -0.4 1.7 -0.3 -0.1 0.9 0.1 -0.2 -0.5 0.1 -0.3
Leg fat mass (left) 0.5 2.1 8.8 -1.2 -3.0 -1.1 -1.0 -1.5 -2.0 -2.4 -1.0 -1.3 -1.8 -1.1 -0.9 -1.4 -2.7 -0.0 -0.6 -1.8 -2.3 -1.6 -0.9 -1.5 -0.7 -0.5 0.0 -2.2 -1.7 -1.3 -1.0 -1.0 -1.5 0.0 -2.0 -1.2 -1.7 -1.2 -1.2 -1.9 -1.6 -1.6 -0.0 -0.6 -0.9 -1.5 -1.0 -1.3 -1.4 -1.1 -1.0
Arm predicted mass (left) 0.9 4.7 13.8 -2.2 -3.6 -0.9 1.2 -1.8 -1.6 -1.6 -1.3 -1.5 -1.8 -2.6 -2.1 -3.7 -3.7 -1.1 -2.7 -1.8 -1.4 -1.3 -1.8 -3.3 1.0 -1.7 0.0 -2.2 -1.6 -2.1 0.6 -3.0 -2.8 0.0 -2.7 -2.9 -2.6 -1.9 -1.9 -1.7 -2.2 -2.0 -3.5 -1.3 -2.1 -2.8 -2.4 -2.3 -1.8 -2.5 -1.9