TWAS hub - IPO9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2090	0.0430	4.2e-08	0.086	0.063	0.128	0.093	0.098	1.3e-10	3.8e-08	2.3e-15	2.3e-11	5.9e-12
2	YFS	Blood	0.0482	0.0126	7.3e-07	0.040	0.022	0.037	0.041	0.043	4.4e-13	5.5e-08	3.2e-12	2.2e-13	5.5e-14

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Number of incorrect matches in round	7.6	12.7	24.4	-1.0	-4.9
Qualifications: nursing, teaching	7.3	11.3	13.2	3.6	3.1
BMI	7.0	40.5	43.8	-6.1	-6.6
Wheeze or whistling in the chest in last year	6.8	12.2	20.8	-4.6	-1.9
Body mass index (BMI)	6.6	28.0	28.1	-5.3	-5.3
Pulse rate, automated reading	6.6	21.2	40.3	-1.4	-6.3
Pulse rate	6.4	10.8	18.9	-1.7	-4.3
Arm fat mass (right)	6.2	25.4	28.3	-5.3	-4.7
Medication: Metformin	5.6	7.9	12.1	-3.5	-1.9
Health satisfaction	5.4	7.1	8.2	-2.4	-2.9
Arm fat mass (left)	5.4	22.2	24.5	-4.9	-4.5
Arm fat percentage (right)	5.2	20.5	24.6	-5.0	-4.1
Leg fat mass (right)	5.1	19.9	20.3	-4.4	-4.5
Leg fat mass (left)	5.0	19.4	21.5	-4.2	-4.6
Shortness of breath walking on level ground	4.9	5.8	6.8	-2.6	-2.2
Impedance of leg (left)	4.8	23.2	37.1	6.1	3.1
Schizophrenia vs Biploar Disorder	4.7	6.3	7.1	-2.7	-2.3
Overall health rating	4.7	10.0	10.7	-3.0	-3.3
Medication: Aspirin	4.7	6.1	8.6	-2.9	-1.9
Impedance of whole body	4.6	23.4	32.3	5.7	3.8
Medication: Lisinopril	4.5	5.9	5.9	-2.4	-2.4
Waist circumference	4.4	16.1	19.4	-4.4	-3.6
Weight	4.4	21.6	26.2	-5.1	-4.1
Whole body fat mass	4.4	18.5	19.3	-4.4	-4.2
Arm fat percentage (left)	4.3	17.1	19.5	-4.4	-3.8
Impedance of leg (right)	3.9	18.7	27.4	5.2	3.2
Had menopause	3.9	4.9	7.0	-2.6	-1.6
Noisy workplace	3.9	4.9	5.2	-2.1	-2.3
Impedance of arm (left)	3.9	17.9	18.1	4.2	4.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.9	4.6	8.4	-0.9	-2.9
Alzheimer’s Disease (in mother)	3.7	4.4	6.6	1.5	2.6
Ever had hysterectomy (womb removed)	3.7	4.2	8.2	-0.4	-2.9
Trunk fat mass	3.7	15.7	16.9	-4.1	-3.8
Heart attack/myocardial infarction (self-reported)	3.7	4.8	9.3	-3.0	-0.6
Age at First Birth	3.6	5.2	5.2	2.3	2.3
Tinnitus: Yes, but not now, but have in the past	3.6	3.8	7.0	-2.6	-0.8
Medication: Levothyroxine sodium	3.6	6.0	6.7	-2.6	-2.3
Leg fat percentage (right)	3.6	13.0	16.1	-3.1	-4.0
Body fat percentage	3.5	14.0	14.1	-3.7	-3.8
Leg fat-free mass (left)	3.4	17.9	27.1	-5.2	-2.9
Number of live births	3.4	4.8	6.1	-2.5	-1.9
Leg fat percentage (left)	3.4	12.3	17.5	-2.7	-4.2
Coronary Artery Disease (CAD)	3.3	4.0	4.3	-2.1	-1.9
Hypothyroidism/myxoedema (self-reported)	3.3	6.4	6.7	-2.6	-2.5
Leg predicted mass (left)	3.2	17.1	25.9	-5.1	-2.9
Heart attack	3.2	4.1	8.1	-2.9	-0.4
Emphysema/chronic bronchitis	3.2	3.6	7.0	-2.6	-0.3
Intelligence (Savage-Jansen 2018)	3.1	9.4	11.6	2.7	3.4
Current tobacco smoking	3.1	5.1	7.2	-2.7	-1.7
Mother’s age at death	3.1	3.9	4.6	2.1	1.8
Trunk fat percentage	3.0	11.9	12.4	-3.5	-3.4
Alcohol usually taken with meals	3.0	4.8	4.8	2.2	2.2
Hip circumference	3.0	13.0	16.6	-4.1	-3.1
Smoking status: Current	2.9	4.6	5.3	-2.3	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.8	3.2	6.3	2.5	-0.4
Illnesses of father: Heart disease	2.8	3.9	5.9	1.4	-2.4
Diabetes diagnosed by doctor	2.8	4.7	8.8	-3.0	-0.8
Commuting to job workplace: Walk	2.8	3.0	5.6	2.4	0.7
Basal metabolic rate	2.8	15.7	21.3	-4.6	-3.2
Type 2 Diabetes (T2D) (2018)	2.7	5.1	8.9	-3.0	-1.1
Fluid intelligence score	2.7	5.7	6.4	2.2	2.5
Qualifications: O levels/GCSEs or equivalent	2.7	4.2	4.5	2.1	2.0
Medication: Aspirin	2.7	3.6	4.8	-2.2	-1.5
Leg fat-free mass (right)	2.7	14.2	21.8	-4.7	-2.6
Leg predicted mass (right)	2.7	14.2	21.4	-4.6	-2.6
Arm fat-free mass (left)	2.7	13.8	15.1	-3.9	-3.5
Arm predicted mass (left)	2.7	13.6	16.6	-4.1	-3.2
Qualifications: None of the above	2.6	5.7	7.9	-2.8	-1.9
Fasting Glucose	2.5	3.0	5.4	-0.8	2.3
Maternal smoking around birth	2.5	3.6	6.5	-2.5	-0.9
Impedance of arm (right)	2.5	11.4	12.2	3.5	3.3
Financial situation satisfaction	2.5	3.1	5.3	-2.3	-1.0
Body Mass Index (BMI) (2010)	2.4	3.3	4.9	-2.2	-1.3
Gout (self-reported)	2.4	3.3	4.5	-2.1	-1.4
Mean time to correctly identify matches	2.4	4.6	7.2	-1.4	-2.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.3	2.7	4.8	-2.2	-0.8
Verbal and Numeric Reasoning (VNR)	2.2	5.4	10.0	0.9	3.2
Diverticular disease/diverticulitis (self-reported)	2.2	2.6	3.8	1.2	2.0
Hair/balding pattern: Pattern 2	2.2	2.8	5.3	2.3	-0.5
Whole body fat-free mass	2.2	12.8	17.9	-4.2	-2.8
Whole body water mass	2.2	12.8	18.1	-4.2	-2.7
Medication for pain relief, constipation, heartburn	2.1	3.6	4.7	1.6	2.2
Supplements: Fish oil (including cod liver oil)	2.1	2.7	4.4	1.0	-2.1
HDL Cholesterol	2.0	3.3	6.5	2.6	0.3
Hypothyroidism (self reported)	2.0	4.7	4.8	-2.2	-2.1
Multivitamins +/- minerals	2.0	2.6	2.6	1.6	-1.6
Diabetes (self-reported)	2.0	3.1	5.0	-2.2	-1.1
Arm predicted mass (right)	2.0	10.2	11.5	-3.4	-3.0
Worry (Nagel 2018)	1.9	4.0	7.6	2.8	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.9	2.5	3.2	-1.3	-1.8
Nervous feelings	1.9	3.5	6.3	2.5	0.8
Financial difficulties in last 2 years	1.9	2.6	3.7	-1.2	-1.9
Pain all over the body in last month	1.9	2.0	4.0	-2.0	-0.1
Arm fat-free mass (right)	1.9	9.8	11.9	-3.5	-2.8
Medication: Seretide 50 evohaler	1.9	2.2	4.3	-2.1	0.4
Diastolic blood pressure, automated reading	1.9	5.9	9.1	-1.6	-3.0
Vascular/heart problems diagnosed by doctor	1.9	5.2	8.0	2.8	1.6
Smoking Status	1.8	4.2	4.7	-2.2	-1.9
Average weekly spirits intake	1.8	2.2	3.8	-1.9	-0.8
Ever had bowel cancer screening	1.8	2.1	4.0	0.3	-2.0
Pack years of smoking	1.8	2.7	3.3	-1.4	-1.8
Heel T-Score	1.7	13.8	16.9	3.3	4.1
Ever used hormone-replacement therapy (HRT)	1.7	2.2	3.7	-0.8	-1.9
Trunk fat-free mass	1.7	9.6	12.5	-3.5	-2.6
Chronic bronchitis/emphysema (mother)	1.7	2.0	3.0	-1.7	-1.0
Mineral and other dietary supplements	1.7	2.3	2.9	-1.7	1.3
Ever taken oral contraceptive pill	1.7	1.9	3.4	0.6	1.8
Schizophrenia (2014)	1.6	3.5	7.0	-0.2	-2.6
Pack years adult smoking proportion	1.6	2.4	3.1	-1.3	-1.8
Trunk predicted mass	1.6	9.3	12.3	-3.5	-2.5
Mouth/teeth dental problems: Bleeding gums	1.6	2.1	4.2	2.1	-0.0
Age at first live birth	1.6	2.9	4.2	1.3	2.1
Supplements: Vitamin C	1.6	1.9	2.1	-1.5	-1.3
Average weekly beer plus cider intake	1.6	2.4	3.3	-1.8	-1.2
Suffer from ‘nerves’	1.5	2.3	4.5	2.1	-0.2
Commuting to job workplace: Car/motor vehicle	1.5	1.8	3.2	0.6	1.8
Illnesses of father: None of the above (group 1)	1.5	1.8	3.6	-0.1	1.9
Pain experienced in last month	1.5	2.5	3.6	1.9	1.2
Heart disease (siblings)	1.5	1.9	3.1	-1.8	-0.8
Depression (Nagel 2018)	1.4	2.1	3.9	-0.5	-2.0
Schizophrenia (2018)	1.4	2.9	5.8	-0.1	-2.4
Prostate Cancer	1.4	2.0	2.0	-1.4	-1.4
Primary Biliary Cirrhosis	1.4	2.1	3.4	0.8	1.9
Lung FEV1/FVC ratio	1.4	7.0	13.5	3.7	0.6
Hypertension (Self-reported)	1.4	3.8	6.4	-2.5	-1.1
Pain type(s) experienced in last month: Hip pain	1.4	1.7	2.8	-1.7	-0.8
Ever had prostate specific antigen (PSA) test	1.4	1.6	3.2	0.1	1.8
Alcohol drinker status: Previous	1.4	1.6	2.8	-1.7	0.6
Townsend deprivation index at recruitment	1.3	1.8	1.9	-1.4	-1.3
High blood pressure	1.3	3.7	5.6	-2.4	-1.3
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.2	3.8	-0.8	-1.9
Prospective memory result	1.3	1.6	3.1	-0.4	-1.8
Tense / ‘highly strung’	1.3	2.2	4.0	2.0	0.6
Peak expiratory flow (PEF)	1.3	3.0	4.2	2.0	1.3
Comparative body size at age 10	1.3	3.6	6.1	-1.0	-2.5
Average weekly red wine intake	1.3	2.0	2.2	1.5	1.3
Eye problems/disorders: Glaucoma	1.3	1.6	2.9	-1.7	0.5
Illnesses of father: High blood pressure	1.3	1.6	3.2	-0.2	-1.8
Reaction Time	1.2	2.3	4.5	-0.2	-2.1
Medication: Atenolol	1.2	1.5	2.5	-0.7	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.8	4.0	1.3	2.0
Loud music exposure frequency	1.2	1.3	1.9	-0.9	-1.4
Alcohol drinker status: Never	1.2	1.5	2.6	0.6	1.6
Allergy or Eczema	1.1	3.0	4.8	2.2	1.1
Chronotype (morning person)	1.1	2.4	3.1	1.3	1.8
Hand grip strength (left)	1.1	3.0	3.0	-1.7	-1.7
Sensitivity / hurt feelings	1.1	1.9	2.6	1.6	-1.1
Supplements: Zinc	1.1	1.2	1.8	-0.8	-1.3
Taking other prescription medications	1.1	1.7	2.5	-1.6	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.6	3.5	1.3	1.9
Neuroticism score	1.1	2.2	3.9	2.0	-0.7
Qualifications: College or University degree	1.1	3.4	3.6	1.8	1.9
Chest pain or discomfort	1.1	1.6	3.2	-1.8	-0.0
Loneliness, isolation	1.1	1.5	2.0	1.0	-1.4
Bipolar Disorder or Schizophrenia	1.0	2.3	4.3	0.6	-2.1
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.1	-1.5	0.4
Severe depression (siblings)	1.0	1.1	2.3	-0.1	-1.5
Illnesses of siblings	1.0	1.5	2.9	1.7	0.2
Qualifications: A levels/AS levels or equivalent	1.0	2.3	3.3	1.1	1.8
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.0	0.6	1.4
Ever highly irritable/argumentative for 2 days	1.0	1.2	2.2	-1.5	0.3
Blood clot in the leg (DVT)	1.0	1.2	2.1	-1.4	0.6
Eye problems/disorders: Cataract	1.0	1.1	2.1	-1.5	-0.4
Number of self-reported non-cancer illnesses	1.0	1.7	3.4	-1.8	-0.2
Alzheimer’s Disease (including proxy)	0.9	1.4	2.7	0.1	1.6
Bipolar Disorder (2011)	0.9	0.8	1.0	1.0	0.8
Rheumatoid Arthritis	0.9	1.2	2.4	0.3	-1.6
Lung FVC	0.9	4.7	8.5	-0.9	-2.9
Neuroticism	0.9	2.2	3.2	1.8	-1.1
Hand grip strength (right)	0.9	2.4	4.5	-0.7	-2.1
High blood pressure (mother)	0.9	1.2	1.3	-1.0	1.2
Ever unenthusiastic/disinterested for a whole week	0.9	1.2	1.6	-1.2	-0.9
Medication: Ramipril	0.9	1.1	1.8	-1.4	0.6
Exposure to tobacco smoke at home	0.9	1.0	1.8	1.4	-0.3
Hair/balding pattern: Pattern 4	0.9	2.1	3.0	-1.7	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	1.7	1.3	0.7
Medication: Blood pressure	0.9	1.6	2.7	-1.7	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	3.0	0.9	1.7
Ever depressed for a whole week	0.9	1.1	2.2	0.2	-1.5
Myopia	0.9	1.3	1.4	1.2	1.1
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	1.9	-1.4	0.6
Triglycerides	0.8	1.2	1.3	-1.1	1.1
Ulcerative Colitis	0.8	1.2	2.4	-0.1	-1.5
Stomach or abdominal pain in last month	0.8	1.0	1.2	-0.9	-1.1
Falls in the last year	0.8	1.1	1.4	0.9	1.2
Illnesses of mother	0.8	0.9	1.5	0.6	-1.2
Birth weight	0.8	1.7	1.8	-1.3	1.2
Mouth/teeth dental problems: Loose teeth	0.8	0.9	1.8	-0.2	-1.4
Neck or shoulder pain in last month	0.8	1.1	2.1	0.1	-1.5
Medication: Blood pressure	0.8	1.5	1.7	-1.3	-1.1
Ever smoked	0.8	1.4	2.2	-1.5	-0.8
Unable to work because of sickness or disability	0.8	1.1	2.0	-0.4	-1.4
Alzheimer’s Disease (in father)	0.7	0.8	1.4	-1.2	-0.4
Mean Putamen Volume	0.7	0.8	1.4	-1.2	0.5
Hearing difficulty/problems: Yes	0.7	1.0	2.1	0.1	1.4
Vitamin and mineral supplements	0.7	0.9	1.1	-0.9	1.1
Had other major operations	0.7	0.8	1.6	-0.3	-1.3
Happiness	0.7	0.8	0.9	-1.0	-0.9
Asthma	0.7	1.4	2.4	-1.6	0.5
Breastfed as a baby	0.7	0.9	1.7	1.3	0.4
Pulse wave reflection index	0.7	0.8	1.4	-0.5	1.2
Knee pain experienced in last month	0.7	1.0	1.7	-1.3	-0.6
Medication: Atorvastatin	0.7	0.8	1.6	0.2	1.3
Ulcerative Colitis (UC)	0.6	1.1	2.2	0.3	-1.5
Blood Red Count	0.6	6.2	10.9	-3.3	-1.2
Cardiovascular Disease	0.6	2.0	4.0	-2.0	-0.1
Respiratory disease	0.6	1.3	2.6	0.1	1.6
Relative age of first facial hair	0.6	1.3	2.6	-0.0	1.6
Mouth/teeth dental problems: Dentures	0.6	1.0	1.7	-1.3	-0.5
Angina (self-reported)	0.6	0.8	1.1	-1.1	-0.6
Asthma (self-reported)	0.6	1.2	2.4	-1.5	0.3
Miserableness	0.6	1.0	1.6	-0.6	-1.3
Bipolar Disorder (2018)	0.5	0.8	1.5	1.2	-0.3
Lupus	0.5	0.7	1.4	-0.1	1.2
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.4	0.1	-1.2
Hayfever, allergic rhinitis or eczema	0.5	1.1	1.3	1.1	0.9
Alcohol intake versus 10 years previously	0.5	0.7	1.3	-0.4	-1.1
Worrier / anxious feelings	0.5	0.9	1.1	1.0	0.9
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.2	-1.1	-0.2
Medication: Allopurinol	0.5	0.7	1.3	-1.2	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.0	1.0	0.5
Long-standing illness, disability or infirmity	0.5	0.7	1.5	-1.2	0.0
Back pain experienced in last month	0.5	0.7	0.7	-0.9	-0.8
Osteoporosis (self-reported)	0.5	0.6	0.6	-0.8	-0.7
Irritability	0.5	0.8	1.6	1.3	0.2
Fractured/broken bones in last 5 years	0.5	0.6	1.1	-1.0	-0.3
Depressed Affect (Nagel 2018)	0.4	0.9	1.6	0.4	-1.3
Major Depression (MDD)	0.4	0.5	0.6	-0.6	-0.8
Systolic blood pressure, automated reading	0.4	1.2	2.0	-1.4	-0.6
Angina	0.4	0.5	0.9	-1.0	-0.4
Medication for hormone replacement therapy	0.4	0.5	0.8	-0.4	0.9
Diabetes (mother)	0.4	0.5	0.8	-0.5	-0.9
Past tobacco smoking	0.4	0.8	1.3	1.2	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	0.7	0.7	0.8
Hearing difficulty/problems with background noise	0.4	0.7	1.3	0.2	1.2
Allergy	0.4	1.0	1.5	0.7	-1.2
Father’s age at death	0.4	0.6	0.7	0.8	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	1.1	-0.2	1.1
Worry too long after embarrassment	0.4	0.7	1.0	1.0	0.6
Eye problems/disorders: None of the above	0.4	0.5	0.9	0.9	0.3
Medication: Omeprazole	0.4	0.5	1.0	0.2	-1.0
Alcohol intake frequency.	0.4	0.9	1.5	0.6	-1.2
Number of full sisters	0.4	0.5	1.0	1.0	0.0
Average weekly champagne plus white wine intake	0.4	0.5	1.0	0.2	1.0
Supplements: Calcium	0.4	0.4	0.5	-0.6	-0.7
Number of treatments/medications taken	0.3	0.6	0.7	-0.8	-0.6
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.7	0.2	0.9
Relative age voice broke	0.3	0.4	0.6	0.7	0.5
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.5	0.4	-0.7
Serious illness, injury or assault to yourself	0.3	0.4	0.6	-0.8	0.4
Mouth/teeth dental problems	0.3	0.5	1.0	0.2	1.0
Time employed in main current job	0.3	0.4	0.6	0.8	0.5
Medication: Paracetamol	0.3	0.5	0.8	-0.9	-0.5
Headache pain in last month	0.3	0.5	1.1	-0.0	-1.0
Glaucoma (self-reported)	0.3	0.3	0.6	-0.4	0.7
High blood pressure (siblings)	0.3	0.5	0.8	-0.9	0.4
Number of full brothers	0.3	0.3	0.4	0.7	-0.5
Number of children fathered	0.3	0.4	0.4	-0.6	-0.6
Pulse wave peak to peak time	0.3	0.4	0.8	0.9	-0.2
Migraine (self-reported)	0.3	0.4	0.5	0.5	0.7
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.6	-0.7	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.6	-0.7	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.9	0.2	-0.9
Osteoarthritis (self-reported)	0.3	0.4	0.8	-0.9	0.1
Medication: Gliclazide	0.3	0.3	0.6	-0.8	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.1	1.1	0.1
Hearing aid user	0.3	0.3	0.4	0.6	-0.5
Medication: Bendroflumethiazide	0.3	0.5	0.9	-0.9	0.3
Neuroticism (Nagel 2018)	0.2	0.6	1.1	1.1	-0.2
Irritable Bowel Disease (IBD)	0.2	0.4	0.7	0.3	-0.8
LDL Cholesterol	0.2	0.4	0.6	0.4	0.7
Blood White Count	0.2	1.1	1.8	-1.3	0.7
Height	0.2	4.1	4.9	-2.2	1.8
Waist Hip Ratio (WHR)	0.2	0.9	1.3	0.7	1.1
Hair Pigment	0.2	4.7	7.4	-1.4	-2.7
Fed-up feelings	0.2	0.3	0.5	-0.7	0.3
Chronic bronchitis/emphysema (father)	0.2	0.3	0.5	0.1	0.7
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.4	0.1	0.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	1.0	1.0	-0.3
Lung cancer (father)	0.2	0.2	0.3	0.4	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.0	1.0	0.3
Pulse wave Arterial Stiffness index	0.2	0.3	0.4	-0.7	0.4
Length of working week for main job	0.2	0.2	0.2	0.4	-0.5
Birth weight of first child	0.2	0.4	0.4	0.7	-0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.3	0.6	0.5
Heart disease (mother)	0.2	0.2	0.3	0.5	0.4
Leg pain on walking	0.2	0.2	0.2	-0.5	-0.4
Friendships satisfaction	0.2	0.2	0.5	-0.7	0.0
Medication for cholesterol	0.2	0.2	0.4	0.7	0.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.5	0.1	0.7
Medication: Paracetamol	0.2	0.3	0.6	-0.8	0.2
Risk taking	0.2	0.3	0.6	0.8	0.2
Commuting to job workplace: Cycle	0.2	0.2	0.3	-0.4	0.6
Cholesterol lowering medication	0.2	0.4	0.5	-0.7	-0.4
Breast Cancer	0.1	0.3	0.6	0.1	-0.8
Crohns Disease (2012)	0.1	0.2	0.2	-0.5	0.5
HbA1C	0.1	0.1	0.1	0.1	-0.3
Neuroticism (2016)	0.1	0.1	0.2	0.5	0.2
Blood Eosinophil Count	0.1	0.5	0.6	-0.8	-0.6
Blood Platelet Count	0.1	0.9	1.4	-0.5	-1.2
Systolic Blood Pressure	0.1	0.4	0.9	-0.9	0.1
Tanning	0.1	0.8	1.5	-0.0	1.2
Medication: Co-codamol	0.1	0.1	0.2	-0.4	0.0
Average weekly fortified wine intake	0.1	0.1	0.3	0.5	0.0
Qualifications: CSEs or equivalent	0.1	0.1	0.2	0.4	-0.2
Supplements: Glucosamine	0.1	0.2	0.3	0.6	-0.1
Sitting height	0.1	0.9	1.6	-1.2	-0.5
Forced vital capacity (FVC)	0.1	0.3	0.6	-0.1	-0.8
Medication: Simvastatin	0.1	0.1	0.2	-0.5	0.1
Hair/balding pattern: Pattern 3	0.1	0.1	0.2	-0.2	0.4
Depression (self-reported)	0.1	0.1	0.1	-0.2	-0.3
Standing height	0.1	1.5	3.0	-0.1	1.7
Had major operations	0.1	0.1	0.1	-0.4	0.2
Age at last live birth	0.1	0.1	0.2	-0.4	-0.3
Smoking status: Previous	0.1	0.2	0.2	-0.5	0.3
Breast cancer (self-reported)	0.1	0.1	0.2	-0.5	-0.0
Guilty feelings	0.1	0.2	0.4	0.6	0.1
Wears glasses or contact lenses	0.1	0.1	0.1	-0.2	-0.3
High cholesterol (Self-reported)	0.1	0.2	0.2	0.5	0.3
Number of operations (self-reported)	0.1	0.2	0.3	-0.5	0.1
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.2	0.3	-0.4
Basal cell carcinoma (self-reported)	0.1	0.2	0.3	-0.5	-0.2
Crohns Disease (2017)	0.0	0.0	0.0	0.1	0.1
Ovarian Cancer	0.0	0.0	0.0	-0.2	0.2
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	-0.1	0.0
Diabetes (father)	0.0	0.0	0.0	-0.1	0.0
Age when periods started (menarche)	0.0	0.0	0.0	-0.1	-0.0
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.0	0.1	0.2
Medication: Cholesterol lowering	0.0	0.1	0.1	-0.1	0.4
Medication: Lansoprazole	0.0	0.0	0.1	-0.2	-0.1
Medication: Amlodipine	0.0	0.0	0.0	0.1	-0.1
Forced vital capacity (FVC), Best measure	0.0	0.0	0.0	0.2	0.0
Exposure to tobacco smoke outside home	0.0	0.0	0.0	0.2	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.1	0.1	0.3
Medication: Ibuprofen	0.0	0.1	0.1	-0.2	-0.3
Comparative height size at age 10	0.0	0.1	0.1	-0.2	0.3
Family relationship satisfaction	0.0	0.1	0.1	-0.0	0.3
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.0	0.1	0.1
Illnesses of siblings: Diabetes	0.0	0.0	0.0	0.2	-0.0
Mood swings	0.0	0.1	0.1	0.2	0.2
Commuting to job workplace: Public transport	0.0	0.0	0.1	0.0	-0.3
Age started oral contraceptive pill	0.0	0.1	0.1	-0.0	0.3

Hub : Genes

IPO9

Models

Trait associations