Hub : Genes

IRF7

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Pancreas	0.2830	0.1020	3.1e-03	0.025	NA	-0.002	NA	0.020	3.0e-02	NA	4.1e-01	NA	4.7e-02
2	GTEx	Thyroid	0.1050	0.0460	8.6e-03	0.011	NA	0.000	NA	0.002	4.4e-02	NA	2.9e-01	NA	2.3e-01
3	METSIM	Adipose	0.0706	0.0269	8.7e-04	0.021	0.017	0.026	0.028	0.019	3.2e-04	1.0e-03	7.9e-05	4.3e-05	6.8e-04
4	YFS	Blood	0.0515	0.0131	1.8e-09	0.041	0.033	0.045	0.041	0.050	3.1e-13	6.4e-11	1.3e-14	2.2e-13	4.5e-16
5	TCGA	Breast Invasive Carcinoma	0.0340	0.0162	3.0e-06	0.027	0.029	0.024	NA	0.021	2.5e-06	9.9e-07	9.1e-06	NA	3.5e-05
6	TCGA	Cervical Squamous Cell Carcinoma	0.1890	0.0890	7.4e-03	-0.005	0.002	0.007	NA	0.003	6.5e-01	2.5e-01	1.4e-01	NA	2.1e-01
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0524	0.0235	1.0e-05	0.051	0.041	0.031	NA	0.037	2.0e-06	1.9e-05	1.8e-04	NA	4.8e-05
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1500	0.0620	4.3e-05	0.008	0.058	0.070	NA	0.037	1.1e-01	3.1e-04	8.2e-05	NA	3.5e-03
9	TCGA	Brain Lower Grade Glioma	0.1022	0.0415	2.6e-08	0.053	0.075	0.063	NA	0.063	1.1e-06	7.6e-09	1.2e-07	NA	1.1e-07
10	TCGA	Lung Adenocarcinoma	0.0325	0.0195	3.6e-03	0.006	0.021	0.038	NA	0.022	5.8e-02	1.5e-03	2.5e-05	NA	1.1e-03
11	TCGA	Lung Squamous Cell Carcinoma	0.0460	0.0253	2.6e-04	0.031	0.039	0.017	NA	0.025	1.6e-04	2.5e-05	4.4e-03	NA	6.8e-04
12	TCGA	Pheochromocytoma and Paraganglioma	0.1700	0.0720	2.1e-04	0.068	0.069	0.090	NA	0.106	1.1e-03	1.0e-03	1.9e-04	NA	5.3e-05
13	TCGA	Prostate Adenocarcinoma	0.0598	0.0261	2.8e-06	0.043	0.055	0.059	NA	0.051	2.7e-05	1.8e-06	8.8e-07	NA	4.8e-06
14	TCGA	Skin Cutaneous Melanoma	0.2370	0.1160	3.2e-03	0.017	0.139	0.077	NA	0.069	1.1e-01	1.5e-04	4.4e-03	NA	6.5e-03
15	TCGA	Thyroid Carcinoma	0.0750	0.0280	1.8e-09	0.100	0.086	0.091	NA	0.091	5.8e-10	1.0e-08	3.9e-09	NA	3.5e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	0.3	0.5	1.8	0.0	0.1	-1.1	-1.2	-0.1	-1.2	0.5	-1.4	0.1	0.1	-0.0	-0.9	0.1	0.8	0.5
Bipolar Disorder or Schizophrenia	0.2	0.4	1.7	0.0	-0.7	-0.1	1.3	-0.0	0.5	0.5	0.9	0.1	1.2	0.3	0.9	-0.4	-0.7	-0.2
Depressed Affect (Nagel 2018)	0.2	0.5	3.1	-0.1	-1.8	0.5	0.5	-0.6	-0.1	0.1	-0.4	-0.4	-0.7	-0.5	-0.1	-0.8	1.0	-0.7
Depression (Nagel 2018)	0.4	0.6	1.7	1.1	-1.3	-0.5	0.4	-0.6	-0.0	-0.1	-0.6	-0.1	-1.1	-0.5	-0.4	-0.9	1.0	-1.0
Intelligence (Savage-Jansen 2018)	0.6	1.9	3.9	-1.5	-1.7	1.5	-0.5	-1.8	0.9	-1.6	-0.7	-1.7	-1.0	-1.5	-0.1	-1.4	0.8	-2.0
Neuroticism (Nagel 2018)	0.1	0.2	0.9	0.6	-0.8	0.9	0.7	0.3	-0.1	0.7	-0.1	0.1	0.4	0.0	0.2	0.4	0.4	-0.0
Schizophrenia (2018)	1.0	2.0	6.9	-2.3	-1.0	0.3	2.6	0.2	1.6	0.3	2.4	0.0	1.4	0.4	1.9	-0.3	-1.5	-0.6
Schizophrenia vs Biploar Disorder	1.3	1.7	5.3	0.0	0.3	0.0	2.3	1.2	0.4	1.1	2.2	1.1	1.2	1.4	2.2	0.7	-1.4	0.8
Worry (Nagel 2018)	0.4	0.9	2.3	1.5	0.4	0.1	1.1	1.2	0.5	1.0	0.7	0.7	1.4	0.8	0.8	1.3	-0.2	0.5
Alzheimer’s Disease (in mother)	0.5	0.6	3.8	-0.4	-2.0	0.1	0.8	-0.5	0.6	-0.5	0.3	-0.3	0.0	-0.3	0.6	-0.7	0.6	-1.2
Alzheimer’s Disease (in father)	0.4	0.5	1.5	-0.4	-0.4	0.2	0.9	0.6	-1.0	1.2	0.4	0.8	0.2	0.8	0.6	0.8	-0.2	0.7
Alzheimer’s Disease (including proxy)	0.3	0.5	3.0	-0.5	-1.7	0.4	1.2	-0.1	-0.1	0.3	0.6	0.4	0.0	0.3	0.9	-0.1	0.1	-0.6
Crohns Disease (2017)	0.8	1.7	5.9	-0.4	-1.9	-1.1	-0.6	-2.2	-0.2	-1.5	0.2	-1.4	-1.0	-1.4	-0.6	-2.4	-0.2	-1.4
Irritable Bowel Disease (IBD)	0.5	1.1	4.4	0.4	-1.2	-0.5	-0.8	-1.7	-1.3	-0.6	0.3	-1.0	-0.5	-1.1	-0.6	-2.1	-1.1	-0.7
Ulcerative Colitis (UC)	0.2	0.4	2.3	1.0	0.5	-0.2	-0.3	0.0	-1.4	0.6	0.3	0.1	0.3	-0.1	-0.2	-0.4	-1.5	0.6
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Reaction Time	0.3	0.5	1.7	0.6	-1.2	0.2	-1.0	-0.4	-0.6	0.6	-1.3	-1.0	-0.4	-0.1	-0.7	0.1	0.9	0.1
Verbal and Numeric Reasoning (VNR)	0.3	0.8	2.5	-1.3	-1.0	1.6	-0.2	-1.0	-0.4	-0.9	-0.2	-0.8	-1.2	-0.8	0.2	-0.7	-0.1	-1.3
Breast Cancer	0.6	1.6	18.1	-0.3	-0.6	4.3	1.0	0.3	0.9	0.2	0.2	-0.4	0.5	-0.5	0.1	1.1	0.5	-0.7
Ovarian Cancer	0.4	0.6	3.7	1.1	-0.1	-1.9	0.6	0.0	1.2	0.4	0.5	-0.2	0.7	-0.0	0.5	-0.0	-0.6	0.0
Prostate Cancer	0.7	1.0	5.6	1.5	-0.5	0.6	-0.0	0.1	-2.4	1.4	0.4	0.2	1.5	0.4	0.4	-0.0	-1.0	0.9
Age at First Birth	1.8	2.6	6.8	-0.7	1.6	-2.2	1.4	1.4	-0.5	0.9	2.3	0.9	2.2	1.3	1.6	1.4	-2.6	1.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.6	0.8	7.8	-1.6	-2.8	0.3	-1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.3	0.5	1.4	0.0	-0.2	-1.1	-0.7	-1.0	-0.5	-0.8	0.5	-0.8	0.0	-0.9	-0.5	-1.2	-0.9	-0.3
Mean Putamen Volume	1.0	1.1	3.8	1.6	-0.2	0.5	1.5	0.6	-0.4	0.5	2.0	0.5	0.7	0.8	1.6	0.4	-1.7	0.4
Fasting Glucose	1.5	1.8	7.4	-2.7	-1.5	-0.1	-0.6	-1.5	-0.6	-1.4	-0.3	-2.0	-0.4	-1.7	-0.2	-1.4	-0.5	-1.6
HbA1C	4.1	4.6	7.9	-2.6	-1.4	0.7	-2.5	-2.7	-0.4	-1.8	-2.8	-2.1	-1.9	-2.4	-2.7	-2.2	1.9	-2.3
HDL Cholesterol	0.7	1.2	14.7	3.8	1.8	-0.1	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.1	0.2	1.5	-0.7	-0.5	-0.5	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lupus	12.5	18.9	42.9	-1.5	-5.9	0.0	-1.4	-5.5	4.6	-5.1	-2.6	-5.7	-4.0	-5.0	-2.3	-4.8	4.0	-6.5
Neuroticism (2016)	2.7	3.9	7.4	1.0	2.3	0.8	2.0	2.7	0.1	2.2	1.8	2.5	1.5	2.7	1.5	2.4	-1.4	2.3
Primary Biliary Cirrhosis	4.0	5.7	12.6	-1.5	-3.5	-1.0	-1.4	-2.7	1.3	-2.1	-2.4	-3.1	-2.6	-2.8	-1.6	-2.3	2.5	-3.0
Rheumatoid Arthritis	0.8	1.2	2.7	-1.1	-0.5	-1.1	-0.9	-0.8	1.6	-0.7	-1.0	-1.6	0.6	-1.5	-1.3	-0.1	1.2	-0.8
Schizophrenia (2014)	0.8	1.8	4.5	-1.5	-0.0	0.0	2.1	0.9	-0.4	1.0	1.9	1.1	1.9	1.1	2.1	0.4	-2.0	0.5
Triglycerides	0.3	0.5	5.1	-2.2	-0.9	0.5	-1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.1	0.2	2.3	0.0	0.0	0.0	-1.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	1.8	2.6	12.5	0.0	0.8	-0.4	0.8	0.8	-3.3	1.2	2.1	1.2	0.3	1.2	1.7	0.1	-3.5	1.2
Blood Eosinophil Count	0.2	1.7	6.9	-1.9	-2.6	-0.3	1.0	-1.3	0.2	-0.9	-0.3	-0.3	-1.6	-0.9	0.3	-2.1	0.8	-1.8
Blood Platelet Count	0.2	2.6	8.2	1.2	-1.6	1.6	-2.9	-1.3	-1.9	-0.7	-2.2	-2.0	-0.1	-1.9	-1.8	-1.3	0.6	-0.6
Blood Red Count	0.1	1.0	3.6	0.7	1.9	0.4	-1.8	0.4	-1.5	-0.4	-1.2	-0.5	-0.1	-0.8	-1.3	0.7	-0.4	0.6
Blood White Count	0.3	2.4	14.7	0.2	-0.9	3.8	-1.4	-1.1	1.2	-1.2	-2.0	-1.9	-1.2	-1.2	-0.7	-0.3	1.2	-1.3
Heel T-Score	0.1	0.7	2.3	-1.2	0.5	1.1	-0.8	-0.4	-0.4	-1.3	-0.4	-0.3	-1.5	-0.7	-0.8	-0.5	0.3	-0.6
BMI	0.4	2.1	7.0	-0.9	-2.1	0.9	-1.1	-2.4	-0.6	-0.7	-1.1	-1.6	-1.5	-1.5	-1.0	-2.6	-0.0	-1.2
Height	0.3	5.7	10.9	-0.5	-2.7	-1.5	-0.8	-3.0	2.8	-2.5	-2.0	-3.3	-2.9	-2.6	-0.8	-2.4	2.0	-3.3
Waist Hip Ratio (WHR)	0.4	1.6	6.2	-0.6	-2.5	1.8	0.9	-1.0	1.3	-1.2	0.1	-1.1	-0.3	-1.3	0.5	-0.8	0.7	-2.2
Systolic Blood Pressure	0.4	1.9	4.0	2.0	1.5	0.8	1.4	1.9	0.7	0.9	1.6	1.0	2.0	1.4	0.9	1.6	-0.6	1.2
Smoking Status	0.6	1.4	4.6	-0.3	2.1	0.9	0.1	1.8	1.3	0.7	0.0	1.1	1.3	0.8	0.1	2.1	0.4	1.2
Allergy or Eczema	1.4	3.8	12.1	-0.1	-1.1	1.7	3.5	1.4	-0.3	2.7	2.2	2.1	1.6	2.5	3.0	0.4	-1.1	1.6
Cardiovascular Disease	0.5	1.7	8.5	-0.6	0.6	2.9	2.2	1.1	1.8	0.7	1.2	0.5	1.6	0.4	1.0	0.9	-0.6	0.2
Hypothyroidism (self reported)	7.4	17.1	34.7	-3.3	-4.7	-2.1	-2.5	-5.3	1.5	-5.5	-2.9	-4.6	-3.6	-5.4	-3.2	-5.1	3.2	-5.9
Respiratory disease	1.2	2.6	6.1	-0.0	2.5	0.8	1.2	2.0	0.3	1.5	1.2	2.2	0.4	2.2	1.8	1.3	-2.0	2.1
Type 2 Diabetes (T2D) (2018)	0.1	0.2	1.9	0.0	-0.4	1.4	0.4	0.3	0.3	0.3	0.0	0.2	0.5	0.6	0.6	-0.1	0.3	0.3
Lung FEV1/FVC ratio	0.1	0.7	4.2	-1.5	-0.3	-0.5	-0.0	0.3	-2.1	0.8	0.1	1.1	-0.0	0.7	-0.3	-0.2	-0.0	0.8
Lung FVC	0.4	1.8	6.4	-2.5	-0.9	-0.7	-0.4	-1.2	1.5	-1.5	-1.0	-0.5	-1.2	-1.3	-1.4	-1.2	1.9	-1.4
Neuroticism	0.3	0.7	2.8	1.0	-1.3	0.9	1.7	0.6	-0.0	1.0	0.7	0.8	0.4	0.9	1.1	0.3	0.3	-0.0
Chronotype (morning person)	0.8	1.9	3.3	0.2	-0.4	1.5	-1.5	-1.6	1.3	-1.8	-1.6	-1.8	-1.8	-1.5	-1.1	-1.1	0.8	-1.4
Hair Pigment	0.0	1.3	2.3	-0.6	-0.8	-1.3	-0.7	-1.1	1.1	-1.2	-1.1	-1.4	0.0	-1.4	-1.5	-0.9	1.3	-1.3
Tanning	0.0	0.4	3.0	1.7	0.9	0.2	-0.5	0.7	0.4	0.5	-0.4	0.1	-0.3	-0.1	-0.4	0.7	-0.3	0.7
Hand grip strength (left)	1.1	2.8	6.5	-1.0	-1.4	-2.0	-1.5	-1.9	-1.3	-1.6	-1.2	-1.9	-1.4	-2.6	-1.8	-2.0	0.4	-2.1
Number of treatments/medications taken	1.2	2.1	4.4	-1.8	-2.0	2.1	-0.0	-1.7	2.1	-0.9	-1.0	-1.4	-1.5	-1.1	-0.3	-1.3	1.1	-1.5
Average weekly spirits intake	0.7	0.8	1.8	1.3	-1.1	1.1	-0.5	-0.9	1.4	-0.5	-0.5	-1.1	-0.1	-0.8	-0.6	-0.6	1.3	-0.6
Sensitivity / hurt feelings	0.2	0.3	1.0	-0.3	-0.5	0.7	-0.7	0.0	-0.1	0.1	-1.0	-0.4	0.4	-0.4	-0.8	0.6	0.9	-0.0
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.0	0.6	-1.4	-0.8	0.2	-0.7	0.7	0.3	-0.9	-0.1	-1.0	-0.1	-0.6	-0.9	1.2	-0.5
Hearing difficulty/problems: Yes	1.8	2.7	7.9	0.5	-2.8	-2.5	-0.9	-2.1	-1.3	-1.2	-0.5	-2.0	-1.7	-1.6	-0.5	-2.2	0.2	-1.7
Relative age of first facial hair	0.2	0.3	1.3	0.5	-0.3	-1.1	-0.3	-0.1	0.4	-0.3	-0.7	-0.4	-0.1	-0.5	-0.7	-0.0	1.1	-0.6
Other serious medical condition/disability diagnosed by doctor	1.3	1.6	5.5	-1.5	0.5	-1.5	1.8	0.6	-0.7	0.6	2.3	0.9	0.8	1.1	1.6	0.3	-2.0	0.7
Ever used hormone-replacement therapy (HRT)	0.4	0.6	2.2	-0.1	-1.5	1.4	1.1	-0.4	0.5	0.1	0.2	-0.6	-0.7	-0.0	1.1	-0.6	0.0	-0.5
Ever had hysterectomy (womb removed)	1.1	1.2	4.4	2.1	0.1	1.4	1.3	0.9	1.6	1.5	-0.1	0.7	0.9	0.9	0.4	1.0	0.5	0.9
Systolic blood pressure, automated reading	0.2	0.6	4.0	2.0	-0.6	0.4	-0.0	-0.6	1.2	0.0	0.0	-0.4	-0.2	-0.1	-0.9	-0.7	1.0	-0.1
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.3	0.9	0.7	0.7	0.5	0.9	-0.2	0.8	1.0	0.5	1.5	0.9	0.3	1.0	-0.9	0.9
Angina	1.3	1.8	5.2	-2.2	-0.3	0.4	-1.2	-1.1	1.2	-1.7	-0.9	-2.3	0.9	-1.9	-1.1	-0.1	0.4	-1.5
Medication for hormone replacement therapy	0.4	0.5	2.0	-0.8	-1.4	1.2	0.7	-0.2	0.1	0.5	0.3	0.2	-0.9	0.5	0.8	-0.8	0.3	-0.0
Vitamin and mineral supplements	0.5	0.7	2.2	-0.9	1.5	0.2	0.2	0.9	-0.3	0.7	0.4	0.8	0.3	1.0	0.8	1.0	-0.8	1.2
Supplements: Zinc	0.7	0.8	2.2	0.9	-0.0	0.7	1.3	1.2	-0.5	0.9	0.6	1.5	1.0	1.0	0.8	0.9	0.3	0.4
Medication: Co-codamol	0.8	0.9	5.0	-0.7	-0.7	0.7	2.2	0.6	0.5	0.8	1.0	1.2	-0.6	1.0	1.5	-0.0	-0.4	-0.1
Medication: Metformin	0.3	0.4	2.4	-0.3	-0.1	1.6	-0.0	0.1	1.4	-0.2	-0.2	-0.2	0.3	0.2	0.0	0.1	0.8	0.0
Diabetes (father)	1.5	1.9	5.7	0.8	0.3	0.4	-2.2	-1.4	1.3	-1.4	-2.4	-0.9	-1.6	-1.1	-1.9	-0.8	1.4	-0.8
Diabetes (mother)	0.8	1.0	4.4	-2.1	-0.3	0.7	1.0	-0.6	-0.8	-1.1	0.9	0.4	-0.8	-0.3	0.6	-1.7	-0.8	-1.3
Severe depression (siblings)	0.3	0.3	0.9	0.9	0.0	-1.0	0.3	0.3	-0.1	0.6	0.4	0.5	0.7	0.6	0.4	-0.1	-0.2	0.6
Pack years adult smoking proportion	0.4	0.7	2.8	-0.9	0.6	-0.2	-1.7	-0.3	0.1	-0.3	-1.4	-0.9	-0.5	-0.5	-1.2	0.5	0.9	0.2
Impedance of leg (right)	0.2	0.8	4.1	-0.1	0.6	-0.7	1.0	0.8	-1.1	-0.5	2.0	0.5	0.8	0.2	1.0	0.2	-1.6	0.2
Leg fat-free mass (left)	0.5	2.6	5.9	-0.5	-1.8	-0.9	-1.6	-2.2	1.3	-0.8	-2.4	-2.0	-1.9	-1.5	-1.3	-1.8	1.6	-1.5
Trunk fat percentage	0.2	0.7	2.7	-0.4	-1.6	0.8	1.4	-0.7	0.4	0.6	0.5	0.1	-1.1	0.2	1.1	-1.2	-0.3	-0.2
Hand grip strength (right)	1.3	3.6	8.1	-0.4	-1.0	-1.5	-1.9	-2.2	0.1	-2.4	-1.8	-2.3	-2.2	-2.9	-2.1	-2.0	1.0	-2.4
Townsend deprivation index at recruitment	0.8	1.1	2.9	-1.0	1.0	0.1	0.7	1.0	0.1	1.4	0.9	1.4	1.1	1.7	0.7	1.2	-0.6	1.5
Current tobacco smoking	1.7	2.8	7.3	-1.2	2.7	-0.6	0.8	2.6	0.3	1.4	1.1	1.8	2.3	1.5	0.7	2.7	-0.8	1.9
Average weekly fortified wine intake	0.9	1.1	5.4	1.3	0.1	0.0	1.6	0.8	-0.5	0.4	2.3	0.6	0.9	0.7	1.4	0.1	-1.4	0.3
Maternal smoking around birth	1.5	2.2	5.2	1.4	0.0	0.8	2.3	1.3	0.1	1.9	1.8	1.8	0.3	2.3	2.0	1.2	-0.8	1.3
Fed-up feelings	0.2	0.4	1.2	0.3	-0.8	0.9	1.0	0.3	0.9	0.7	-0.4	0.2	0.4	0.1	0.0	0.3	1.1	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.1	0.8	-0.5	-0.6	0.2	-0.2	1.1	0.2	-0.2	-0.3	-0.0	-0.1	-0.3	-0.1	0.6	-0.2
Relative age voice broke	2.8	4.2	8.8	0.9	2.3	-0.3	2.1	2.4	-0.1	2.2	2.0	1.7	3.0	2.2	2.2	2.6	-2.2	2.2
Taking other prescription medications	0.9	1.4	6.7	-1.8	-1.6	1.2	1.6	-0.8	2.6	-0.3	0.5	-0.5	-0.1	-0.1	1.0	-0.6	0.5	-1.1
Age when periods started (menarche)	0.2	0.5	1.0	1.0	1.0	-0.4	-0.4	0.9	-0.9	0.4	0.2	0.8	0.8	0.6	-0.2	0.6	-0.1	0.8
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	5.2	2.3	-0.9	-0.3	0.7	0.0	1.3	0.4	-0.3	-0.3	0.5	-0.3	0.4	0.3	0.3	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	3.0	-1.1	-1.6	-0.0	-0.2	-1.3	1.6	-1.2	-1.0	-1.2	-1.0	-1.1	-0.6	-1.0	1.4	-1.7
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	3.6	0.9	-0.3	0.8	1.3	0.5	-0.7	0.4	1.9	0.2	-0.4	0.8	1.7	-0.0	-1.5	0.4
Qualifications: CSEs or equivalent	0.6	0.8	2.9	0.0	-0.5	-0.7	-0.6	-1.1	0.8	-1.7	-0.6	-0.6	-1.1	-0.8	-0.6	-1.0	0.8	-1.5
Serious illness, injury or assault to yourself	0.3	0.4	1.1	0.3	-0.4	-0.6	-0.2	-0.9	-0.6	-0.6	0.4	-0.6	0.6	-0.5	0.1	-0.9	-1.0	-0.6
High blood pressure	0.3	0.9	7.3	1.1	0.3	2.7	1.2	0.6	1.1	0.8	0.6	0.1	0.9	0.2	0.2	0.5	-0.4	0.3
Hayfever, allergic rhinitis or eczema	1.3	2.8	7.4	0.4	-0.3	1.0	2.7	1.6	-0.1	2.4	1.8	2.2	1.3	2.5	2.4	0.6	-0.8	1.8
Multivitamins +/- minerals	0.8	1.0	2.0	0.7	-1.0	0.2	-0.5	-0.9	1.4	-0.8	-1.3	-0.9	-1.0	-1.1	-1.1	-0.8	1.4	-1.2
Stomach or abdominal pain in last month	1.2	1.4	5.6	0.8	0.1	-0.3	1.9	1.2	-0.3	1.1	2.0	0.9	2.4	0.6	1.1	0.7	-1.3	0.6
Supplements: Glucosamine	2.0	2.6	4.7	-0.2	-1.7	-1.0	-1.5	-1.9	0.7	-1.5	-2.1	-1.3	-1.3	-1.7	-2.1	-1.8	2.2	-2.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	2.0	0.3	-1.4	-0.0	1.1	-0.2	-0.0	0.4	0.3	0.0	0.1	-0.3	0.3	-0.5	0.4	-0.3
Medication: Atenolol	2.0	2.5	6.2	-0.4	-1.5	0.8	-1.7	-1.8	0.7	-1.5	-1.9	-2.5	-1.0	-2.3	-1.7	-1.1	1.8	-1.6
Medication: Levothyroxine sodium	5.8	9.8	18.5	-2.1	-4.3	-1.0	-1.4	-4.1	1.6	-3.6	-2.7	-3.1	-3.2	-3.4	-2.0	-3.9	3.7	-4.3
Sitting height	2.0	14.4	24.8	-2.1	-4.0	-2.8	-2.8	-5.0	2.2	-4.4	-3.3	-4.9	-3.5	-4.8	-3.0	-4.4	3.1	-4.9
Chronic bronchitis/emphysema (father)	2.8	3.3	11.0	-0.1	-2.3	0.0	-1.4	-1.9	1.0	-1.7	-2.2	-1.5	-1.8	-1.6	-1.9	-1.5	3.3	-2.1
High blood pressure (mother)	0.4	0.6	2.1	0.7	-1.2	-0.9	0.9	-0.8	-0.7	-0.0	0.6	-0.3	-0.8	-0.0	0.8	-1.4	-0.6	-0.6
Body mass index (BMI)	0.2	0.7	3.6	-0.4	-1.9	0.8	0.2	-1.3	-0.0	0.5	-0.6	-0.5	-1.2	-0.4	-0.0	-1.5	0.2	-0.5
Impedance of leg (left)	0.2	0.8	4.7	-0.5	0.2	-0.1	1.2	0.6	-0.8	-0.6	2.2	0.4	0.6	0.2	1.2	-0.0	-1.7	0.0
Leg predicted mass (left)	0.5	2.7	5.9	-0.5	-1.9	-0.8	-1.6	-2.3	1.2	-0.8	-2.4	-2.1	-1.9	-1.6	-1.3	-1.9	1.5	-1.5
Trunk fat mass	0.2	1.0	4.5	-0.8	-2.1	0.2	0.7	-1.4	0.7	0.2	-0.3	-0.7	-1.6	-0.5	0.4	-1.7	0.2	-0.7
Waist circumference	0.3	0.9	6.1	0.1	-2.5	0.7	1.0	-1.3	0.1	0.5	0.1	-0.4	-0.8	-0.3	0.7	-1.6	-0.2	-0.7
Number of incorrect matches in round	0.5	0.8	2.9	0.6	-1.7	0.3	-0.0	-1.1	0.6	-0.6	-1.0	-0.8	-1.4	-0.7	-0.0	-1.2	0.9	-1.0
Past tobacco smoking	0.6	1.2	3.2	-0.4	0.1	0.5	1.3	0.7	-1.7	0.6	1.7	1.2	0.3	1.2	1.7	0.3	-1.8	0.7
Alcohol usually taken with meals	0.8	1.4	3.2	1.0	-0.7	-0.1	-1.8	-1.5	-0.8	-0.7	-1.2	-1.5	-1.2	-1.5	-1.3	-1.6	-0.4	-0.5
Nervous feelings	0.2	0.3	1.7	0.4	-0.1	-0.2	-0.1	0.3	1.3	0.2	-1.0	-0.1	0.7	-0.1	-0.3	0.7	1.1	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.2	0.8	-0.1	0.9	0.3	-0.4	0.5	0.3	0.4	-0.6	0.5	0.3	0.3	-0.5	0.8	0.2	0.6
Hearing difficulty/problems with background noise	0.1	0.1	0.6	-0.8	-0.4	-0.4	-0.2	-0.0	0.6	-0.2	-0.5	-0.3	0.0	-0.3	-0.1	-0.1	0.4	-0.1
Hair/balding pattern: Pattern 2	0.4	0.5	2.9	-1.7	-0.5	0.3	-0.2	-0.7	1.1	-0.7	-0.1	-0.7	-0.4	-0.7	-0.4	-0.2	0.4	-0.5
Had menopause	0.9	1.1	2.2	0.0	0.7	-0.1	1.5	1.0	1.2	1.3	1.3	0.2	1.3	1.0	1.3	1.2	-1.1	1.1
Had other major operations	1.1	1.4	6.0	-2.4	-1.6	0.3	-0.1	-1.3	1.2	-0.5	-0.9	-1.2	-1.3	-0.9	-0.4	-1.0	1.4	-1.2
Forced vital capacity (FVC)	0.9	3.3	4.8	-1.4	-1.4	-2.2	-1.4	-2.0	1.8	-2.2	-1.4	-1.8	-1.9	-1.9	-2.0	-1.6	2.1	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	2.6	-1.1	-1.5	1.6	-0.3	-1.5	1.5	-1.3	-1.1	-1.4	-1.2	-1.2	-0.3	-1.0	1.0	-1.6
Ever unenthusiastic/disinterested for a whole week	3.9	4.8	8.9	-1.3	-1.2	-0.7	-2.1	-2.3	1.8	-2.6	-2.5	-2.7	-1.1	-2.9	-3.0	-1.5	2.5	-2.8
Qualifications: None of the above	0.1	0.3	1.1	-0.5	0.4	1.0	-0.6	-0.0	-0.2	-0.8	0.0	-0.7	-0.1	-0.6	-0.4	0.0	-0.7	-0.2
Financial difficulties in last 2 years	0.1	0.2	0.8	-0.8	0.0	0.2	-0.2	0.1	-0.9	0.4	-0.4	0.1	0.6	0.1	-0.0	-0.2	-0.3	0.1
Mouth/teeth dental problems	0.3	0.5	1.8	0.8	-0.2	1.1	0.9	0.1	1.4	-0.3	0.2	0.2	-0.8	0.5	0.8	0.1	1.0	-0.4
Heart attack	0.7	1.0	2.8	-0.7	1.0	0.9	-1.7	-0.7	-0.4	-1.4	-0.8	-1.1	-0.5	-1.2	-1.5	-0.1	-0.2	-0.7
Allergy	0.8	1.8	4.8	-0.2	0.1	-0.6	-1.9	-1.4	-0.7	-2.2	-0.9	-1.7	-1.2	-2.0	-1.6	-0.9	0.0	-1.6
Pain all over the body in last month	0.4	0.4	2.7	-0.4	-1.6	-0.8	0.8	-0.5	-0.3	0.5	-0.0	0.5	-0.1	0.1	0.4	-1.1	0.1	-0.1
Diabetes (self-reported)	0.3	0.5	3.9	-0.4	0.0	2.0	0.4	0.5	0.4	0.3	0.5	0.1	0.9	0.6	0.6	0.7	0.1	0.6
Hayfever/allergic rhinitis (self-reported)	3.4	4.5	10.4	0.8	0.7	0.1	3.2	2.4	-0.9	2.6	2.6	2.5	2.5	2.6	2.7	1.7	-1.7	1.9
Medication: Ramipril	0.7	0.9	5.3	0.3	-0.3	0.1	0.5	0.3	2.1	-0.2	-1.1	0.1	-0.6	0.2	-0.2	0.5	2.3	-0.8
Medication: Simvastatin	0.4	0.6	4.7	-0.9	-0.5	2.2	0.7	-0.1	0.7	-0.3	-0.1	-0.2	0.7	-0.3	0.6	0.2	0.4	-0.8
Fluid intelligence score	0.8	1.6	3.7	-1.8	-1.4	1.2	-0.6	-1.5	-0.1	-1.8	-0.6	-1.3	-1.4	-1.5	-0.1	-1.5	0.5	-1.9
Illnesses of siblings	0.6	0.9	5.2	0.5	-0.9	-1.4	-0.6	-0.9	-2.3	-0.2	0.8	-0.6	-0.1	-0.4	-0.2	-1.2	-1.0	-0.0
Neuroticism score	0.3	0.6	4.0	0.5	-2.0	-0.1	0.3	-0.7	0.7	-0.0	-0.7	-0.9	0.3	-0.7	-0.3	-0.4	1.0	-0.9
Weight	0.4	2.0	6.6	-0.6	-2.6	-0.4	-0.4	-2.2	1.0	-0.4	-1.4	-1.6	-1.9	-1.2	-0.5	-2.1	0.9	-1.4
Impedance of arm (right)	0.4	1.7	3.3	1.2	1.8	-0.9	1.1	1.8	-0.3	0.5	1.6	1.3	1.5	1.2	1.3	1.6	-1.1	1.1
Arm fat percentage (right)	0.1	0.5	2.2	-0.3	-1.5	0.5	0.9	-0.6	0.0	0.9	0.0	0.1	-0.9	0.2	0.6	-1.0	-0.1	-0.0
Trunk fat-free mass	0.9	5.1	10.7	-0.8	-3.1	-1.7	-2.1	-3.3	0.7	-1.6	-2.5	-3.0	-2.3	-2.4	-1.8	-3.0	1.5	-2.3
Hip circumference	0.1	0.5	1.7	0.8	-1.3	-0.1	0.5	-1.0	0.2	0.7	-0.2	-0.4	-0.9	0.2	0.5	-1.1	-0.2	0.0
Time employed in main current job	1.1	1.3	7.4	-0.8	-0.6	-0.2	0.7	0.0	2.7	-0.3	-1.3	-0.1	-0.9	-0.2	-0.4	0.4	2.6	-1.0
Alcohol intake versus 10 years previously	1.1	1.7	5.0	1.2	2.2	0.1	0.2	1.8	0.2	1.4	0.7	0.7	1.9	1.0	-0.1	2.2	-0.8	1.6
Father’s age at death	1.8	2.5	5.6	-1.2	0.7	-0.3	1.4	1.3	-2.4	1.2	2.2	1.3	1.0	1.6	2.3	0.8	-2.4	1.6
Worrier / anxious feelings	0.4	0.7	4.0	2.0	1.0	-0.0	-0.4	0.9	0.1	0.8	-0.5	0.2	1.3	0.1	-0.6	1.1	-0.2	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.2	1.1	-0.1	-0.6	1.0	0.4	-0.0	-0.6	1.1	-0.1	0.4	0.1	0.5	0.2	-0.0	-0.2	0.4
Falls in the last year	0.6	0.8	1.9	-1.0	-1.4	-1.2	0.9	-0.4	-0.9	0.7	0.8	0.6	-0.9	1.0	0.9	-1.0	-0.5	0.2
Hair/balding pattern: Pattern 3	0.4	0.6	1.9	0.3	0.6	0.6	0.3	1.0	-0.0	0.6	-0.1	1.3	-1.0	1.4	0.8	0.5	0.6	0.9
Number of live births	1.1	1.5	3.9	0.5	1.7	-1.2	1.2	1.5	0.9	1.4	1.0	1.1	2.0	0.7	0.2	1.6	-0.8	1.4
Forced expiratory volume in 1-second (FEV1)	0.7	2.2	5.4	-1.2	-1.4	-2.3	-1.0	-1.6	0.7	-1.4	-1.2	-1.0	-1.8	-1.3	-1.8	-1.6	1.8	-1.3
Pulse rate	0.2	0.3	0.7	0.6	-0.7	0.4	0.8	0.0	-0.5	0.4	0.7	0.5	0.4	0.6	0.5	-0.5	-0.7	0.2
Happiness	0.3	0.4	1.7	0.4	-1.1	-0.8	0.3	-0.7	1.3	0.1	0.2	-0.7	0.2	-0.5	-0.6	-0.6	0.3	-0.4
Noisy workplace	0.7	0.8	2.8	0.1	0.4	0.9	-1.1	-0.4	1.2	-0.2	-1.3	-0.0	-1.4	-0.2	-1.4	0.0	1.7	0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.6	0.2	0.8	1.3	0.7	0.9	0.5	0.2	0.2	0.7	0.3	0.4	0.2	0.9	0.6	0.2
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.1	1.4	1.6	-0.9	0.9	1.3	1.5	0.8	1.0	1.3	0.1	1.8	1.1	1.1	-0.6	1.3
Mouth/teeth dental problems: Dentures	0.3	0.5	2.1	-1.4	0.2	0.0	-1.0	-0.5	-0.3	-0.3	-0.0	-0.3	0.5	-0.8	-1.0	-0.6	-0.9	0.2
Asthma	1.1	2.1	3.8	-0.1	1.1	1.2	1.9	1.7	1.1	1.6	1.4	1.9	0.5	2.0	1.9	1.2	-1.3	1.6
Medication: Ibuprofen (e.g. Nurofen)	6.7	8.5	16.9	0.6	-3.8	-1.0	-3.1	-4.1	0.6	-2.3	-3.4	-3.5	-3.9	-2.7	-2.4	-3.4	2.9	-2.7
Medication: Cholesterol lowering	0.5	0.8	4.7	-2.2	0.8	1.5	0.7	0.5	1.4	0.1	0.2	0.6	0.5	0.3	0.2	0.8	0.3	0.1
Depression (self-reported)	0.8	1.0	4.6	-0.2	1.6	-0.7	-0.3	0.8	2.1	0.1	-0.4	0.0	1.3	-0.3	-1.2	1.5	0.7	0.5
Medication: Lansoprazole	1.5	1.8	7.1	-2.7	-2.2	0.5	0.4	-1.9	0.8	-0.6	-0.2	-1.4	-0.6	-1.3	-0.2	-1.7	-0.0	-1.6
Prospective memory result	0.8	1.0	3.8	-0.5	1.1	0.9	0.6	0.8	-0.3	0.7	1.5	0.4	1.9	0.9	0.5	0.6	-1.5	1.0
Lung cancer (father)	3.3	3.8	7.3	1.2	2.4	1.5	1.7	2.6	0.3	2.7	1.7	2.1	0.4	2.5	1.6	2.7	-1.2	2.5
Illnesses of mother	0.6	0.8	2.0	0.8	0.6	1.2	-1.3	0.4	0.4	0.1	-1.1	-0.9	1.3	-0.5	-0.7	1.4	0.2	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	3.8	0.3	-0.7	-2.0	-0.6	-0.8	0.3	-0.4	-0.8	-0.0	-1.4	-0.3	-1.2	-0.9	1.3	-0.3
Pulse wave Arterial Stiffness index	0.7	0.8	3.6	1.9	-1.3	0.8	1.1	-0.3	0.4	-0.2	0.5	0.0	-1.5	0.5	0.9	-0.3	0.5	-0.4
Impedance of arm (left)	0.7	3.0	6.2	1.4	2.3	-0.6	1.5	2.5	-0.5	1.2	2.0	2.0	1.6	1.9	1.7	2.2	-1.3	1.8
Arm fat mass (right)	0.2	1.0	4.4	-0.4	-2.1	0.3	0.1	-1.5	0.5	0.2	-0.8	-0.8	-1.5	-0.6	-0.2	-1.7	0.6	-0.7
Trunk predicted mass	1.0	5.5	11.2	-0.8	-3.1	-1.7	-2.2	-3.4	0.7	-1.7	-2.6	-3.1	-2.4	-2.5	-1.9	-3.0	1.6	-2.4
Standing height	0.5	4.5	8.7	-0.6	-2.0	-2.9	-1.5	-2.5	2.2	-2.4	-1.8	-3.0	-2.0	-2.3	-1.3	-2.0	1.7	-2.5
Length of working week for main job	2.2	2.5	6.8	-1.6	-0.8	0.4	-2.1	-1.5	0.8	-1.4	-2.6	-1.4	-1.9	-1.6	-1.9	-0.8	1.8	-1.4
Exposure to tobacco smoke at home	0.4	0.4	1.7	0.2	-0.8	-0.5	-0.2	-0.3	-1.2	0.6	0.4	-0.7	0.8	-0.3	0.3	-0.1	-1.3	0.1
Breastfed as a baby	0.5	0.7	2.3	-0.6	-1.5	-0.8	0.8	-0.7	0.2	-0.1	0.9	-1.1	0.3	-0.8	0.7	-0.8	-0.8	-1.0
Tense / ‘highly strung’	0.7	1.2	3.9	0.6	0.7	0.3	1.2	1.4	1.4	1.6	-0.1	0.6	1.9	0.7	0.7	2.0	-0.1	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	7.7	-1.0	-0.9	-2.8	-0.7	-1.0	1.2	-0.4	-0.6	-1.0	0.1	-1.0	-1.6	-1.0	0.8	-0.8
Hair/balding pattern: Pattern 4	0.3	0.8	2.7	0.4	-0.1	-1.2	-0.5	-0.3	0.3	-0.8	-0.4	-1.6	1.4	-1.6	-0.7	0.1	-0.2	-1.0
Birth weight of first child	0.8	1.5	3.5	0.6	-1.9	-0.3	0.1	-1.5	1.7	-1.1	-1.0	-1.1	-0.8	-1.1	-0.4	-1.5	1.9	-1.7
Peak expiratory flow (PEF)	1.0	2.2	4.0	-0.4	-1.0	-1.9	-1.8	-2.0	-0.7	-1.2	-1.7	-1.2	-1.9	-1.6	-2.0	-1.7	0.5	-1.1
Pulse wave reflection index	0.4	0.5	1.4	0.4	-0.8	0.9	1.0	-0.2	1.2	-0.5	0.4	-0.1	-1.1	0.2	0.7	-0.0	0.7	-0.7
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.2	-0.8	-0.7	-0.3	-0.4	-0.4	-1.1	-0.0	-0.9	-0.1	0.3	-0.7	-1.1	-0.9	0.8	-0.4
Loud music exposure frequency	2.2	2.4	4.8	-0.8	-2.2	0.3	-0.8	-1.9	1.5	-1.7	-0.6	-2.2	-1.3	-1.7	-1.1	-1.6	1.6	-2.2
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	5.1	0.6	-0.3	0.8	2.2	0.9	0.1	0.9	1.7	1.3	0.3	1.6	2.3	0.4	-0.6	0.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.6	0.5	0.4	-0.3	-0.6	-0.1	-0.3	0.3	-0.1	-0.3	0.8	0.2	-0.4	0.3	-0.2	0.4
Blood clot in the leg (DVT)	0.9	1.2	4.1	0.6	-0.1	-0.5	-1.8	-0.6	0.5	-0.0	-1.6	-2.0	0.6	-1.4	-1.7	0.8	0.9	-0.2
Medication: Paracetamol	2.7	4.4	8.1	1.6	2.3	0.3	1.5	2.6	-0.5	2.7	1.8	2.2	2.2	2.4	1.7	2.2	-2.5	2.8
Headache pain in last month	0.7	1.1	6.2	-1.1	-0.7	-0.6	0.4	-0.6	2.5	-1.1	-0.1	-1.4	0.3	-1.3	-0.4	-0.9	0.5	-1.3
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	5.0	1.0	-0.3	-2.2	-0.6	-0.1	-1.5	0.3	0.2	-0.3	0.0	0.1	0.3	-0.0	-0.8	0.5
Glaucoma (self-reported)	0.5	0.6	4.2	-1.0	-0.4	2.0	0.3	-0.3	1.1	-0.3	-0.3	-0.7	0.3	-0.2	0.1	0.4	0.6	-0.7
Gout (self-reported)	1.5	2.1	3.6	1.4	1.3	0.0	1.8	1.9	0.0	1.7	1.5	1.8	1.3	1.7	1.6	1.4	-0.8	1.7
Hypothyroidism/myxoedema (self-reported)	6.4	12.6	23.6	-2.6	-4.2	-1.8	-2.0	-4.4	1.8	-4.5	-3.1	-4.0	-3.2	-4.4	-2.6	-4.0	3.7	-4.9
Medication: Amlodipine	0.2	0.3	2.0	-0.1	0.0	1.4	0.5	0.3	0.2	-0.3	-0.5	-0.0	-0.1	-0.3	0.1	0.4	0.4	-0.9
Medication: Ventolin 100micrograms inhaler	0.8	1.0	3.8	0.1	0.8	0.2	0.9	1.5	0.6	1.5	-0.1	1.0	1.1	1.2	0.3	1.9	0.2	0.9
Birth weight	0.2	0.3	2.7	-0.6	0.1	-1.6	-0.5	0.0	-0.5	-0.0	-0.4	0.4	-0.9	0.4	0.4	-0.1	0.4	0.3
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.3	0.8	0.0	-1.5	1.3	0.5	-0.2	0.4	0.7	1.1	-0.8	1.3	1.3	0.2	-0.4	0.2
High blood pressure (siblings)	0.3	0.4	2.6	0.8	-0.1	0.9	1.0	0.1	1.6	-0.2	0.3	0.3	-0.3	0.3	0.8	0.2	0.2	-0.5
Forced vital capacity (FVC), Best measure	0.4	1.4	3.9	-0.4	-1.1	-2.0	-1.0	-1.3	1.1	-1.0	-1.1	-1.0	-1.5	-1.0	-1.3	-1.1	1.4	-0.8
Body fat percentage	0.2	0.8	3.3	-0.7	-1.8	0.7	1.4	-0.7	0.1	0.9	0.4	0.1	-1.1	0.2	1.1	-1.2	-0.4	-0.1
Leg fat percentage (right)	0.2	0.7	2.9	-1.0	-1.7	0.4	1.2	-0.7	-0.5	0.9	0.5	0.1	-0.7	0.1	0.9	-1.3	-0.7	0.0
Arm fat-free mass (right)	0.8	4.2	8.9	-0.9	-2.9	-0.7	-1.7	-3.0	1.0	-1.3	-2.4	-2.6	-2.4	-2.1	-1.7	-2.6	1.7	-2.0
Exposure to tobacco smoke outside home	0.2	0.2	0.7	-0.8	0.1	0.2	-0.1	0.4	-0.7	0.6	-0.2	0.1	-0.3	0.6	0.0	0.9	0.2	0.5
Comparative body size at age 10	0.3	0.8	2.4	-1.6	-0.8	-0.7	-0.4	-1.1	0.9	-0.6	-1.1	-1.0	-1.3	-0.7	-0.0	-0.8	0.4	-0.8
Number of full brothers	0.4	0.5	1.4	0.3	0.8	0.2	1.0	0.7	0.8	0.2	0.6	1.2	-0.4	1.0	0.9	0.3	-0.4	0.2
Worry too long after embarrassment	0.4	0.6	1.9	0.9	-1.4	-0.4	-0.2	-1.0	-0.2	-0.7	-0.2	-1.2	0.5	-1.1	-0.5	-0.6	-0.1	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.4	-1.5	-0.0	-1.5	-0.6	-0.5	1.4	-0.5	-0.4	-0.8	0.7	-0.7	-1.1	0.0	0.3	-0.4
Wheeze or whistling in the chest in last year	0.3	0.5	1.7	-1.3	-1.0	1.2	0.1	-0.8	-0.0	0.2	-0.6	-0.3	-1.1	-0.2	-0.1	-0.5	0.0	-0.5
Number of children fathered	3.0	3.4	7.0	-1.0	-2.5	-0.4	-1.6	-2.5	0.7	-1.4	-1.5	-2.5	-2.7	-1.8	-1.5	-2.3	1.3	-1.8
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	4.7	1.6	-0.6	0.0	-1.4	-1.0	1.6	-2.0	-1.8	-1.1	-1.4	-1.5	-1.5	-0.4	2.2	-1.8
Age at first live birth	0.1	0.1	0.4	-0.5	0.3	-0.6	-0.1	0.1	-0.6	0.0	0.2	-0.3	0.1	-0.2	-0.2	-0.0	-0.4	0.3
Pulse wave peak to peak time	0.7	0.8	4.2	-2.0	0.8	-1.2	-1.3	-0.2	-0.3	-0.2	-0.8	-0.5	0.9	-0.9	-1.1	-0.2	-0.2	-0.1
Health satisfaction	0.7	1.0	4.9	-0.6	-2.2	-0.3	0.5	-1.6	0.3	-0.2	0.3	-0.5	-0.7	-0.3	-0.1	-2.2	0.3	-0.8
Shortness of breath walking on level ground	0.8	0.9	3.1	-0.1	-1.7	0.4	1.3	-0.7	-1.0	0.5	1.8	-0.3	0.2	0.1	0.8	-1.3	-1.4	-0.2
Qualifications: College or University degree	0.1	0.4	1.0	0.3	-0.7	-0.4	-0.4	-0.8	-0.1	-0.6	-0.4	-0.5	-1.0	-0.6	-0.8	-0.9	1.0	-0.8
Eye problems/disorders: None of the above	1.1	1.3	3.7	0.0	-0.1	-1.7	1.3	0.8	-1.0	1.9	1.1	1.4	0.1	1.4	1.3	0.1	-0.9	1.4
Mouth/teeth dental problems: Loose teeth	0.6	0.8	3.6	-1.3	1.0	-0.1	-0.9	-0.1	-1.9	0.6	0.4	0.4	-0.4	0.5	-0.3	-0.2	-1.3	1.1
Emphysema/chronic bronchitis	1.4	1.6	3.1	-1.2	1.2	0.2	1.4	1.4	0.0	1.5	1.2	1.1	0.9	1.7	1.4	1.8	-0.9	1.4
Medication for pain relief, constipation, heartburn	1.0	1.6	4.4	-0.5	-0.3	-1.0	-1.9	-1.0	-0.9	-1.6	-1.3	-1.0	-1.0	-1.5	-2.1	-0.7	1.8	-1.2
Neck or shoulder pain in last month	1.7	2.4	6.1	0.6	2.5	0.4	0.4	1.8	-1.4	1.9	1.0	1.5	1.5	1.4	0.4	1.8	-1.9	2.4
Medication: Blood pressure	0.4	0.7	8.0	0.5	-0.2	2.8	0.3	-0.1	0.7	-0.4	-0.2	-0.3	0.1	-0.4	-0.3	-0.1	0.4	-0.8
Angina (self-reported)	1.1	1.4	4.9	-2.2	-0.3	0.5	-0.8	-0.9	1.5	-1.5	-0.6	-2.0	0.8	-1.6	-0.6	0.0	0.4	-1.4
Migraine (self-reported)	1.2	1.5	7.4	-0.9	-0.4	1.1	-0.1	-0.8	2.7	-1.0	-1.1	-1.1	-1.0	-1.2	-0.8	-0.4	2.2	-1.2
Medication: Ibuprofen	5.5	6.5	14.3	0.4	-3.3	-0.9	-2.7	-3.8	0.1	-2.2	-2.7	-3.0	-3.7	-2.4	-1.8	-3.5	1.9	-2.4
Medication: Allopurinol	0.2	0.2	1.2	0.3	0.1	-0.3	1.0	0.4	1.1	0.7	0.3	0.5	0.4	0.4	0.2	0.3	0.2	0.2
Medication: Omeprazole	0.5	0.7	2.7	-1.2	-0.7	0.4	1.6	0.3	0.0	0.2	1.4	0.3	-0.3	0.4	1.3	-0.1	-0.9	-0.2
Medication: Seretide 50 evohaler	0.4	0.5	3.2	-1.2	-0.8	1.8	0.4	-0.0	0.3	-0.0	-0.3	-0.3	-0.7	0.1	0.8	0.2	-0.0	-0.3
Mean time to correctly identify matches	0.4	0.8	1.9	1.4	-1.2	0.6	-1.1	-0.4	-1.0	0.9	-1.4	-0.9	-0.8	0.0	-0.6	0.1	0.8	0.5
Heart disease (mother)	0.5	0.6	2.3	-1.1	0.8	0.8	0.5	0.4	-0.6	0.4	0.5	1.5	-1.2	1.2	0.3	0.1	0.0	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	6.2	-0.6	1.7	-0.9	0.1	0.5	-1.4	0.3	1.5	0.9	1.1	0.4	0.3	-0.0	-2.5	1.0
Whole body fat mass	0.2	1.0	5.0	-0.7	-2.2	0.1	0.5	-1.5	0.5	0.4	-0.4	-0.8	-1.5	-0.5	0.3	-1.7	0.2	-0.6
Leg fat mass (right)	0.3	1.1	4.8	-1.2	-2.2	0.1	0.3	-1.5	0.3	0.2	-0.6	-0.9	-1.5	-0.7	0.1	-1.9	0.1	-0.8
Arm predicted mass (right)	0.8	4.2	9.3	-1.0	-2.7	-1.0	-1.7	-3.0	1.1	-1.4	-2.3	-2.6	-2.4	-2.1	-1.7	-2.7	1.5	-2.0
Pulse rate, automated reading	0.1	0.3	0.9	0.9	-0.3	-0.4	0.6	-0.4	0.1	-0.2	0.8	0.3	-0.5	0.5	0.6	-0.6	-0.9	-0.2
Alcohol intake frequency.	0.6	1.3	3.8	-0.2	1.7	0.3	-0.0	1.4	-0.4	1.7	0.3	1.0	1.1	1.1	0.4	1.3	-1.6	2.0
Comparative height size at age 10	0.6	3.1	6.5	0.5	-1.8	-2.4	-1.1	-2.4	1.1	-2.0	-0.7	-2.5	-2.2	-1.7	-0.7	-2.3	0.4	-1.9
Number of full sisters	0.5	0.6	1.5	-0.6	0.2	0.9	1.2	0.9	-0.0	0.9	0.8	1.2	0.7	1.0	0.9	0.4	-0.6	0.6
Suffer from ‘nerves’	0.7	1.1	5.4	1.4	-0.5	1.2	-0.2	-0.1	2.3	-0.3	-1.2	-0.5	0.6	-0.3	-0.5	0.7	2.1	-0.7
Overall health rating	0.2	0.3	1.1	-0.7	-0.9	1.0	0.6	-0.2	-0.3	1.1	0.2	0.1	-0.2	0.5	0.3	-0.1	-0.3	0.5
Chest pain or discomfort	0.5	0.7	2.4	-1.6	-1.4	0.7	0.1	-0.5	1.4	-0.4	0.1	-1.3	0.1	-0.9	-0.3	-0.4	0.3	-0.9
Had major operations	0.4	0.5	2.6	-0.8	0.2	-0.2	-0.0	0.6	-0.7	1.0	0.5	0.1	1.6	0.4	0.3	0.7	-0.9	0.9
Age at last live birth	0.3	0.4	2.2	0.4	1.5	-0.3	-0.6	0.6	0.3	0.4	-0.1	0.2	0.4	0.5	-0.4	0.8	-0.1	1.0
Family relationship satisfaction	0.5	0.6	2.7	1.6	0.7	0.2	-0.6	0.7	-1.1	1.0	-0.1	0.3	0.8	0.5	-0.2	0.8	-0.7	1.1
Leg pain on walking	0.2	0.3	1.6	1.3	-0.1	0.1	0.7	0.3	-0.7	0.1	0.9	0.2	0.8	-0.0	0.3	-0.0	-0.3	0.0
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.8	-1.6	-1.1	-0.1	1.5	0.4	-1.0	1.6	1.0	0.4	1.7	0.5	1.5	0.3	-1.4	0.4
Commuting to job workplace: Car/motor vehicle	3.2	3.7	11.0	-1.0	1.2	0.9	0.7	2.0	-3.2	2.1	1.8	1.1	2.4	1.2	1.5	1.6	-3.3	2.2
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.0	0.6	-1.2	-0.5	0.5	-0.6	0.6	-0.4	-0.7	-0.2	-1.4	-0.2	-0.1	-0.5	1.4	-0.9
Medication: Aspirin	0.7	0.9	3.5	0.5	-0.8	1.9	0.8	-0.4	1.8	-0.9	-0.3	-0.5	-0.5	-0.4	0.5	-0.4	1.0	-1.3
Supplements: Vitamin C	0.6	0.7	3.1	0.9	0.4	0.6	0.8	1.1	-0.3	0.6	1.0	0.5	1.8	0.5	0.8	0.9	-0.5	0.5
Knee pain experienced in last month	0.7	1.1	5.7	-0.5	1.2	-0.3	-0.6	0.2	-2.1	0.7	0.6	0.1	0.8	0.4	0.3	0.0	-2.4	1.4
Hypertension (Self-reported)	0.3	0.9	7.9	1.2	-0.1	2.8	1.1	0.5	1.3	0.8	0.2	0.0	0.8	0.2	0.1	0.4	0.1	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	5.6	-0.8	-1.6	1.1	2.1	-0.1	2.4	-0.1	0.7	0.1	-0.5	0.2	1.6	-0.2	0.7	-0.9
Illnesses of father: Heart disease	2.6	3.6	15.3	-0.2	3.9	1.6	0.3	2.6	0.1	1.4	0.3	1.9	1.9	1.6	0.6	3.1	-1.4	2.3
Illnesses of siblings: Diabetes	0.3	0.4	2.5	-0.3	0.1	0.4	-0.0	-0.1	1.6	-0.8	-0.6	0.0	-0.2	-0.4	-0.5	-0.4	1.0	-0.6
Smoking status: Previous	0.7	1.0	2.8	0.4	0.4	-0.2	-1.4	-0.5	1.7	-0.6	-1.3	-1.3	0.4	-1.1	-1.7	0.0	1.2	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	3.5	0.3	-1.9	-1.3	0.0	-1.0	-1.2	-0.0	0.2	-0.8	0.2	-0.7	0.3	-1.2	-0.9	-0.9
Whole body fat-free mass	0.8	4.4	9.1	-0.7	-2.7	-1.2	-2.0	-3.0	1.0	-1.4	-2.6	-2.8	-2.2	-2.2	-1.7	-2.6	1.6	-2.0
Leg fat-free mass (right)	0.6	3.0	6.5	-0.6	-2.0	-0.6	-1.7	-2.4	1.3	-0.9	-2.5	-2.1	-2.0	-1.6	-1.4	-1.9	1.7	-1.6
Arm fat percentage (left)	0.2	0.7	2.1	-0.2	-1.2	0.8	1.4	-0.1	-0.1	1.4	0.4	0.7	-0.7	0.8	1.1	-0.6	-0.3	0.5
Average weekly red wine intake	0.4	0.5	2.7	1.3	0.0	1.6	0.8	0.5	0.2	0.5	0.3	0.6	0.3	0.8	0.6	0.7	0.5	0.1
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.6	1.6	0.2	-1.3	-0.5	0.5	0.6	0.7	-1.0	0.4	0.7	0.3	-0.5	0.5	0.4	0.7
Mood swings	0.5	0.9	3.5	-1.0	-1.9	0.8	0.2	-1.0	0.8	-0.6	-0.7	-0.7	-0.5	-0.8	-0.5	-1.4	1.0	-1.1
Loneliness, isolation	0.3	0.4	0.8	-0.4	-0.8	-0.9	0.4	-0.3	0.8	-0.5	-0.0	0.0	-0.6	-0.2	-0.5	-0.9	0.9	-0.8
Long-standing illness, disability or infirmity	0.4	0.7	3.0	-1.7	0.2	-0.0	1.3	0.1	0.6	0.4	1.3	0.2	0.2	0.3	0.7	-0.2	-1.6	0.3
Ever had bowel cancer screening	0.5	0.6	2.0	-1.4	0.1	0.9	-0.6	-0.4	1.4	-0.8	-0.4	-1.1	0.0	-0.9	-1.0	-0.0	0.6	-0.5
Diabetes diagnosed by doctor	0.3	0.5	3.0	-0.8	-0.2	1.7	0.8	0.5	1.0	0.1	0.5	0.4	0.3	0.7	0.8	0.4	0.5	0.3
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	3.9	0.1	-0.3	-2.0	-1.5	-1.2	0.6	-1.2	-1.3	-1.6	0.2	-1.7	-1.7	-0.7	0.9	-1.1
Friendships satisfaction	0.5	0.6	1.9	-1.0	-0.0	0.9	-0.8	-0.2	0.1	-0.7	-0.4	-1.1	1.4	-1.2	-0.7	0.2	-0.2	-0.6
Qualifications: nursing, teaching	0.3	0.5	1.8	0.1	0.3	0.1	0.8	0.6	0.1	1.3	0.7	0.0	1.0	0.6	0.8	0.9	-1.0	0.8
Commuting to job workplace: Walk	0.4	0.5	2.8	0.1	0.4	-0.0	-0.3	0.2	1.2	-0.9	-0.5	-0.1	0.1	-0.2	-0.5	0.5	1.7	-0.9
Eye problems/disorders: Cataract	1.0	1.1	2.9	0.1	1.4	1.4	-1.7	0.0	1.4	-0.7	-1.2	-1.1	0.5	-0.9	-1.5	1.2	0.7	0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	4.1	0.1	0.6	-2.0	0.4	0.9	-0.2	0.8	-0.4	0.7	1.2	0.2	-0.2	0.9	0.2	0.4
Medication for cholesterol	0.6	1.0	4.9	0.1	0.6	-2.2	-1.8	-0.3	-1.4	0.0	-1.2	-0.2	-0.8	-0.1	-1.1	0.2	0.4	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	2.8	-0.2	-1.6	1.1	-0.4	-1.7	1.3	-1.3	-0.7	-1.1	-0.8	-1.4	-1.2	-1.6	1.1	-1.5
Back pain experienced in last month	0.4	0.6	2.3	0.1	-1.1	1.5	0.9	0.1	-0.7	1.3	0.9	0.4	0.7	0.8	0.7	-0.2	-0.5	0.4
Mineral and other dietary supplements	0.5	0.7	3.2	-0.8	-0.2	-1.3	1.1	0.1	-0.8	0.5	1.8	0.3	-0.0	0.3	1.1	-0.5	-1.2	0.6
Breast cancer (self-reported)	0.9	1.1	9.5	-0.8	0.7	-3.1	-0.9	-0.5	1.0	-1.2	-0.6	-0.4	-0.4	-0.4	-0.8	-0.4	0.6	-0.6
Asthma (self-reported)	1.0	2.0	3.3	-0.3	1.4	1.1	1.5	1.8	1.2	1.5	1.1	1.8	0.7	1.8	1.7	1.4	-1.4	1.6
Osteoporosis (self-reported)	0.3	0.3	1.4	0.1	-0.2	-0.8	-0.5	-0.2	0.8	-0.1	-0.7	-0.5	0.0	-0.7	-1.2	0.1	0.8	-0.4
Osteoarthritis (self-reported)	1.4	1.8	9.8	-0.2	1.1	-1.4	0.8	0.6	-2.0	0.8	1.7	0.9	1.4	0.6	1.0	-0.2	-3.1	1.3
Medication: Aspirin	0.6	0.8	4.6	0.1	-0.5	2.1	1.3	-0.0	1.5	-0.5	0.2	0.2	-0.2	0.1	1.0	-0.1	0.5	-0.9
Medication: Gliclazide	0.3	0.4	2.3	0.1	0.1	1.5	0.1	0.3	-0.7	0.4	0.8	-0.2	0.7	-0.1	-0.0	-0.0	-1.0	0.4
Illnesses of father: None of the above (group 1)	0.7	0.8	2.8	1.5	-1.3	-1.7	0.7	-0.2	-1.4	0.7	0.7	0.4	-0.5	0.3	0.7	-1.1	-0.5	0.3
Smoking status: Current	1.0	1.6	4.3	-1.1	2.0	-0.5	0.7	2.1	0.2	1.0	0.8	1.6	1.4	1.1	0.5	2.0	-0.4	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	2.8	-0.2	-1.4	0.0	1.7	-0.2	0.2	0.1	1.0	0.6	0.0	0.3	0.5	-0.7	0.2	-0.5
Whole body water mass	0.8	4.4	9.0	-0.8	-2.8	-1.1	-2.0	-3.0	1.1	-1.3	-2.6	-2.8	-2.3	-2.2	-1.7	-2.6	1.7	-2.0
Leg predicted mass (right)	0.6	3.0	6.6	-0.7	-2.0	-0.5	-1.7	-2.4	1.4	-0.9	-2.6	-2.2	-2.0	-1.7	-1.5	-1.9	1.7	-1.6
Arm fat mass (left)	0.2	0.9	4.8	-0.4	-2.2	0.2	0.4	-1.4	0.2	0.5	-0.5	-0.5	-1.4	-0.4	0.2	-1.7	0.4	-0.6
Number of self-reported non-cancer illnesses	1.9	3.2	10.0	0.2	0.4	2.0	3.2	1.7	1.3	2.2	2.4	2.0	1.3	2.1	2.1	1.0	-0.6	1.7
Average weekly champagne plus white wine intake	0.6	0.8	2.9	-1.7	-1.3	-0.8	0.3	-1.0	0.4	-0.8	0.2	-0.9	-0.1	-0.9	-0.0	-1.3	0.1	-1.1
Miserableness	0.4	0.8	3.1	-0.6	-1.8	0.3	-0.1	-1.0	-0.1	-0.4	-0.8	-0.9	-0.0	-1.1	-0.7	-1.1	1.0	-1.2
Guilty feelings	0.4	0.6	1.7	-1.3	-0.7	-0.2	-1.1	-1.0	-0.3	-0.2	-1.1	-1.3	-0.4	-1.0	-0.7	-0.4	-0.2	-0.4
Wears glasses or contact lenses	0.8	0.9	1.9	0.7	-1.2	0.0	-0.4	-1.0	1.3	-0.9	-1.0	-1.4	-0.4	-1.3	-0.6	-0.8	1.1	-1.0
Ever taken oral contraceptive pill	1.4	1.5	7.5	-0.1	-1.4	-2.7	-0.9	-1.5	-0.1	-0.7	-1.4	-0.7	-1.8	-0.6	-0.6	-1.6	0.6	-0.8
Hearing aid user	0.6	0.7	3.2	-0.8	-0.5	-1.4	0.9	0.4	-0.5	0.3	1.8	0.1	1.2	-0.0	0.3	0.1	-1.1	0.1
Mother’s age at death	0.7	0.9	4.2	0.7	1.3	-2.1	-0.7	0.6	-0.8	0.5	0.4	-0.2	1.3	-0.1	-0.2	0.6	-1.5	1.1
Financial situation satisfaction	2.1	2.6	4.9	-1.6	-1.1	0.1	-2.1	-2.1	-0.1	-1.5	-1.6	-2.0	-1.3	-2.0	-2.2	-2.0	1.1	-1.4
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.0	-1.0	-0.7	-0.8	0.7	0.2	-0.2	-0.3	0.2	-0.1	0.0	-0.4	0.3	-0.3	-0.1	-0.6
Commuting to job workplace: Public transport	0.3	0.3	1.1	0.5	-0.7	-0.8	0.4	-0.6	-0.5	-0.2	0.5	0.2	-1.0	0.2	0.7	-0.8	-0.2	-0.3
Eye problems/disorders: Glaucoma	0.5	0.6	2.9	-0.7	-0.0	1.7	1.2	0.3	1.3	0.0	0.7	-0.1	1.1	0.3	0.5	0.7	0.0	-0.5
Medication: Blood pressure	0.5	1.0	3.0	1.4	0.1	1.4	1.7	0.7	1.4	0.6	1.1	0.1	1.1	0.3	1.0	0.6	-0.9	0.1
Pain type(s) experienced in last month: Hip pain	1.5	1.9	5.2	0.6	1.7	-0.3	0.3	1.2	-1.5	1.8	1.3	1.1	1.1	1.7	0.9	1.2	-1.6	2.3
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.7	0.8	1.2	1.6	-0.5	1.1	0.4	0.6	-1.2	0.9	0.9	0.8	-0.2	1.3	0.7	0.7
High cholesterol (Self-reported)	0.6	1.0	7.1	-2.7	0.5	2.2	0.7	-0.0	1.0	-0.2	0.6	0.1	0.8	-0.2	0.3	0.5	-0.4	-0.3
Medication: Bendroflumethiazide	0.7	1.0	2.3	0.2	-1.2	1.1	-0.4	-1.2	0.8	-1.0	-0.6	-1.4	-0.6	-1.4	-0.8	-1.3	0.1	-1.5
Medication: Paracetamol	1.9	2.9	5.0	1.1	1.8	-0.2	1.3	2.0	-0.1	2.1	1.6	1.7	2.2	1.8	1.3	1.9	-2.2	2.2
Medication: Lisinopril	1.0	1.4	4.9	0.4	-0.2	0.5	1.8	0.8	0.9	0.8	2.2	-0.2	1.4	0.6	1.7	0.7	-1.8	0.5
Medication: Atorvastatin	0.5	0.6	4.6	-2.1	-0.7	0.5	0.6	-0.8	0.4	-0.6	0.8	-0.2	-0.3	-0.6	-0.2	-0.9	-0.2	-0.7
Illnesses of father: High blood pressure	0.6	0.7	1.4	0.8	0.4	1.2	1.1	0.8	0.4	0.8	0.9	0.5	0.2	0.9	1.0	0.9	-1.0	0.7
Alcohol drinker status: Never	0.2	0.2	1.3	0.8	-0.1	-0.0	-0.2	-0.1	-1.2	-0.2	-0.0	0.3	-0.8	0.3	0.4	-0.3	-0.3	0.0
Ever smoked	0.6	1.1	6.2	0.8	0.5	0.0	-0.5	0.4	2.5	0.3	-1.6	-0.2	0.0	-0.2	-1.0	0.9	2.0	0.0
Basal metabolic rate	0.7	3.8	8.2	-0.7	-2.8	-1.1	-1.6	-2.9	1.0	-1.2	-2.3	-2.5	-2.2	-2.0	-1.4	-2.6	1.5	-1.9
Leg fat percentage (left)	0.3	0.9	4.0	-1.2	-2.0	0.7	1.2	-1.0	-0.3	0.7	0.4	-0.2	-1.0	-0.1	0.8	-1.6	-0.7	-0.2
Arm fat-free mass (left)	1.0	5.1	11.3	-0.9	-3.3	-0.7	-1.7	-3.4	1.2	-1.6	-2.4	-2.9	-2.5	-2.4	-1.7	-3.0	1.7	-2.4
Number of operations (self-reported)	0.8	1.1	6.5	-2.3	0.2	-0.2	-0.1	0.2	2.6	0.2	-1.0	-0.5	0.3	-0.3	-0.6	0.5	1.6	0.1
Average weekly beer plus cider intake	1.9	2.8	5.7	-0.5	0.6	1.4	2.0	2.4	-0.1	2.2	1.6	1.7	2.2	1.8	1.9	2.2	-1.0	1.5
Irritability	0.2	0.4	2.1	0.5	-1.4	1.1	0.5	-0.1	-0.5	1.1	-0.5	0.1	0.6	0.2	0.1	0.1	0.3	0.1
Risk taking	0.7	1.0	2.8	-1.4	0.7	1.7	0.8	1.0	-0.5	1.1	0.7	0.8	1.5	0.8	0.7	1.0	-1.1	0.9
Ever had prostate specific antigen (PSA) test	0.9	1.0	3.2	-0.4	-1.5	-0.1	-0.9	-1.4	-0.0	-0.8	-0.3	-1.1	-1.5	-1.0	-0.8	-1.8	0.4	-0.7
Fractured/broken bones in last 5 years	0.4	0.5	1.8	0.5	0.0	-1.3	-1.2	-0.2	-0.1	0.6	-0.2	-0.3	1.3	-0.0	-1.2	0.2	0.1	0.8
Age started oral contraceptive pill	2.9	3.6	6.8	2.5	1.8	-1.1	2.1	2.1	-0.3	1.4	2.6	2.0	1.3	2.3	2.3	1.4	-1.9	1.9
Diastolic blood pressure, automated reading	0.4	1.1	4.0	2.0	0.1	1.3	1.3	0.6	1.9	0.9	0.6	0.9	-0.7	1.3	0.6	0.4	0.7	0.6
Ever depressed for a whole week	1.8	2.2	5.1	-0.4	-1.4	-0.8	-0.9	-1.4	1.4	-1.9	-1.3	-2.0	-0.4	-2.1	-1.6	-0.8	1.7	-2.2
Unable to work because of sickness or disability	0.4	0.5	2.7	-1.6	0.2	-1.2	-0.3	0.3	0.6	0.3	-0.3	-0.7	1.0	-0.4	-0.7	1.0	0.3	0.1
Commuting to job workplace: Cycle	0.4	0.4	1.7	1.3	-0.1	0.8	-0.8	-0.4	-0.8	-0.9	-0.2	-0.4	-0.8	-0.5	-0.3	-0.3	-0.1	-0.6
Myopia	1.8	2.6	8.4	0.1	-1.5	-1.2	-0.9	-1.2	2.9	-1.1	-2.3	-1.6	-1.7	-1.1	-1.1	-0.6	2.9	-1.5
Vascular/heart problems diagnosed by doctor	0.4	1.2	8.9	-0.6	-0.8	-3.0	-1.1	-1.0	-0.5	-0.9	-0.8	-0.3	-1.3	-0.4	-0.4	-0.9	0.9	-0.6
Cholesterol lowering medication	0.7	1.0	5.2	-1.6	-0.2	2.3	0.6	-0.6	0.3	-0.8	1.0	-0.8	0.9	-0.8	0.4	-0.3	-1.0	-0.8
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	4.1	-2.0	-0.8	0.7	1.9	0.3	0.3	0.2	1.7	0.3	-0.8	0.6	1.9	-0.2	-1.2	-0.1
Pain experienced in last month	0.3	0.6	2.6	0.3	-0.8	0.5	-0.2	-0.2	0.1	-0.8	-0.8	-0.0	-1.6	-0.1	0.3	0.1	1.5	-0.9
Supplements: Calcium	0.8	0.9	5.6	2.4	1.0	-1.5	-0.0	0.8	0.3	0.6	-0.5	0.8	-0.4	0.6	0.0	1.1	0.1	0.7
Basal cell carcinoma (self-reported)	0.7	0.8	3.1	1.7	-1.3	0.7	0.0	-0.3	1.0	-0.5	-0.9	-0.2	-1.1	0.0	0.1	-0.3	1.6	-0.9
Heart attack/myocardial infarction (self-reported)	0.8	1.1	3.4	-0.6	1.1	0.8	-1.8	-0.7	-0.4	-1.5	-1.1	-1.1	-0.6	-1.2	-1.7	0.0	0.0	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	3.8	0.7	-0.3	-0.6	-1.7	-0.6	0.1	0.1	-1.4	-1.9	0.9	-1.3	-1.6	0.6	0.7	-0.1
Heart disease (siblings)	1.0	1.2	6.0	-0.9	1.5	2.5	0.2	1.2	1.2	0.7	-1.0	0.7	-0.5	0.8	0.2	1.6	0.8	0.7
Alcohol drinker status: Previous	2.1	2.4	4.5	-0.2	1.7	-0.2	1.4	2.1	-0.6	1.9	1.4	1.8	1.9	1.6	1.0	1.8	-1.6	2.0
Pack years of smoking	0.4	0.6	2.2	-0.7	0.0	-0.5	-1.5	-0.6	-0.0	-0.6	-1.2	-1.2	-0.5	-0.7	-1.1	0.2	0.8	-0.2
Impedance of whole body	0.3	1.7	4.8	0.8	1.5	-0.5	1.6	1.7	-0.4	0.3	2.2	1.4	1.2	1.1	1.5	1.4	-1.4	1.0
Leg fat mass (left)	0.3	1.2	5.0	-1.2	-2.2	0.3	0.3	-1.6	0.3	0.2	-0.6	-0.9	-1.5	-0.7	0.2	-1.9	0.0	-0.7
Arm predicted mass (left)	1.0	5.2	11.2	-0.7	-3.1	-1.0	-1.9	-3.3	1.1	-1.6	-2.6	-2.9	-2.5	-2.4	-1.9	-3.0	1.8	-2.3