TWAS hub - ITFG3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1420	0.0530	1.2e-03	0.022	NA	0.029	NA	0.037	6.4e-03	NA	1.9e-03	NA	4.8e-04
2	GTEx	Artery Aorta	0.1980	0.0530	6.4e-06	0.082	NA	0.127	NA	0.101	2.7e-05	NA	1.7e-07	NA	3.5e-06
3	GTEx	Artery Tibial	0.1057	0.0369	1.1e-03	0.093	NA	0.072	NA	0.090	1.0e-07	NA	2.7e-06	NA	1.6e-07
4	GTEx	Colon Sigmoid	0.2120	0.0790	3.5e-03	0.000	NA	0.048	NA	0.017	3.2e-01	NA	8.3e-03	NA	7.9e-02
5	GTEx	Esophagus Mucosa	0.0930	0.0400	7.1e-03	0.003	NA	0.004	NA	-0.004	2.0e-01	NA	1.6e-01	NA	8.0e-01
6	GTEx	Muscle Skeletal	0.1090	0.0354	4.2e-04	0.053	NA	0.056	NA	0.057	6.5e-06	NA	3.3e-06	NA	3.0e-06
7	GTEx	Nerve Tibial	0.1994	0.0551	6.6e-06	0.056	NA	0.077	NA	0.099	8.4e-05	NA	4.3e-06	NA	1.8e-07
8	GTEx	Skin Sun Exposed Lower leg	0.1550	0.0470	2.5e-05	0.090	NA	0.109	NA	0.093	6.4e-08	NA	2.9e-09	NA	4.1e-08
9	GTEx	Thyroid	0.0910	0.0350	1.9e-03	0.029	NA	0.007	NA	0.023	2.7e-03	NA	9.1e-02	NA	6.3e-03
10	GTEx	Whole Blood	0.0680	0.0280	8.4e-03	0.043	NA	0.016	NA	0.026	7.8e-05	NA	1.2e-02	NA	1.6e-03
11	METSIM	Adipose	0.1082	0.0410	1.8e-04	0.032	0.027	0.072	0.055	0.047	1.2e-05	4.8e-05	6.9e-11	1.2e-08	1.3e-07
12	YFS	Blood	0.1557	0.0329	0.0e+00	0.076	0.096	0.108	0.117	0.102	9.4e-24	1.3e-29	2.3e-33	4.7e-36	1.1e-31
13	TCGA	Breast Invasive Carcinoma	0.0248	0.0150	5.5e-03	0.010	0.008	0.007	NA	0.002	3.2e-03	7.7e-03	1.2e-02	NA	9.0e-02
14	TCGA	Colon Adenocarcinoma	0.1190	0.0460	3.2e-05	0.067	0.070	0.074	NA	0.068	1.0e-04	7.2e-05	4.3e-05	NA	8.9e-05
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0372	0.0202	5.3e-03	0.009	0.012	0.002	NA	0.009	3.2e-02	1.3e-02	1.7e-01	NA	3.3e-02
16	TCGA	Soft Tissue Sarcoma	0.0760	0.0400	6.7e-03	0.065	0.053	0.051	NA	0.060	1.1e-04	4.2e-04	5.6e-04	NA	1.8e-04
17	TCGA	Thyroid Carcinoma	0.0620	0.0260	1.0e-04	0.053	0.033	0.023	NA	0.026	7.0e-06	3.6e-04	2.2e-03	NA	1.3e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Illnesses of father: None of the above (group 1)	8.4	10.4	19.6	-3.9	-3.2	-3.1	-1.7	-4.2	-0.2	-3.8	-3.2	-3.1	-3.5	-1.8	-2.5	-3.5	-4.4	-4.2	-2.5	-3.1
Diabetes (father)	6.9	8.6	18.8	3.8	2.7	3.4	0.6	3.6	0.3	3.9	2.2	0.1	4.0	1.3	2.8	4.3	3.6	3.3	3.0	1.3
Diabetes diagnosed by doctor	6.7	11.1	18.4	4.1	3.9	4.3	2.4	3.8	-0.6	4.2	3.1	0.9	4.0	2.7	2.9	3.6	3.6	3.9	3.9	1.3
Type 2 Diabetes (T2D) (2018)	6.3	11.8	19.6	4.1	4.0	4.4	3.3	3.5	-1.4	4.0	3.1	1.1	3.9	2.4	2.8	3.9	3.5	4.3	4.3	1.3
Blood Red Count	5.0	48.8	204.5	6.1	1.4	8.6	7.7	1.2	-13.0	7.6	5.5	0.5	6.0	7.8	5.3	3.5	3.5	5.7	14.3	-3.5
Diabetes (self-reported)	4.5	7.0	11.9	3.2	3.0	3.4	2.1	2.8	-1.2	3.3	2.5	0.7	3.1	2.0	2.3	2.9	2.8	3.1	3.2	0.8
Medication: Gliclazide	4.5	5.1	11.1	2.5	1.8	2.8	2.4	2.4	-2.0	2.4	1.6	0.5	2.9	2.0	1.6	2.5	2.3	2.8	3.3	-0.1
Illnesses of father: High blood pressure	4.3	5.3	10.8	2.6	2.2	1.9	1.2	3.2	1.2	2.5	2.0	2.6	2.4	0.5	1.7	2.8	3.3	3.1	1.4	2.3
Medication: Metformin	4.0	5.7	10.2	3.0	2.4	2.9	0.2	2.3	-0.9	3.0	2.5	-0.3	3.2	2.5	2.2	2.7	2.4	2.5	3.2	0.2
Qualifications: O levels/GCSEs or equivalent	3.8	6.0	11.5	-3.4	-2.7	-3.3	-2.4	-3.3	0.9	-3.2	-1.8	0.4	-2.5	-1.9	-2.2	-1.9	-3.1	-2.4	-2.9	0.2
Medication: Lisinopril	3.6	4.7	13.0	2.8	2.3	2.4	1.0	3.6	0.4	2.8	2.6	0.7	2.4	1.2	2.0	1.7	2.9	2.2	1.8	1.3
Ever had prostate specific antigen (PSA) test	3.4	3.9	7.7	2.7	2.8	2.6	0.8	1.9	1.4	2.7	1.8	1.1	1.7	2.1	1.2	1.2	2.3	1.9	0.7	2.4
Pain experienced in last month	3.0	5.0	9.3	-3.0	-1.6	-2.8	-2.0	-2.4	1.9	-3.0	-1.8	-0.4	-2.3	-1.2	-1.5	-2.5	-2.9	-2.5	-3.0	0.3
Fasting Glucose	2.9	3.5	6.7	1.9	2.0	1.5	0.1	2.1	1.1	1.9	1.4	2.5	1.6	1.5	1.1	2.6	2.4	2.6	0.8	2.5
Medication: Co-codamol	2.7	3.1	7.1	1.9	1.8	1.8	1.4	2.7	-1.6	2.1	1.0	0.2	2.4	1.7	1.8	1.2	2.2	1.9	2.0	-0.3
Medication for cholesterol	2.7	4.1	7.9	-2.5	-1.6	-2.3	-1.7	-2.8	0.4	-2.7	-2.2	-0.6	-2.8	-1.7	-1.6	-2.2	-2.3	-1.9	-2.2	-0.2
Back pain experienced in last month	2.7	4.0	7.3	2.7	1.9	2.4	1.8	2.3	-1.1	2.6	1.0	0.8	2.3	0.3	1.5	2.7	2.5	2.4	2.3	0.6
Diabetes (mother)	2.5	3.2	6.6	2.5	1.5	2.5	0.6	1.9	0.5	2.6	1.7	0.2	2.3	0.7	1.6	1.7	2.3	2.2	2.1	0.6
Stomach or abdominal pain in last month	2.5	3.1	7.8	2.6	0.5	1.9	-0.3	2.4	0.1	2.6	1.4	-1.2	2.8	2.4	1.3	0.7	2.2	1.7	1.5	-0.2
Neck or shoulder pain in last month	2.5	3.5	8.3	2.7	1.8	2.2	1.6	2.1	0.1	2.9	1.2	0.5	2.4	0.4	1.8	1.8	2.7	2.3	1.6	0.6
Illnesses of siblings: Diabetes	2.5	3.1	6.5	2.1	1.5	2.4	2.0	2.0	-2.3	2.3	0.4	-1.0	1.8	0.4	1.2	1.6	1.7	1.5	2.5	-1.0
Pulse rate	2.4	4.0	9.3	-1.5	-2.5	-2.0	-0.9	-1.1	0.6	-1.7	-3.1	-2.4	-1.7	-3.0	-1.3	-2.1	-1.6	-2.3	-1.3	-2.6
Number of full brothers	2.4	3.1	6.7	2.5	1.1	2.3	1.5	1.1	-0.8	2.6	1.6	-0.5	1.7	2.2	2.0	1.5	2.0	1.7	2.3	-0.4
Mean Putamen Volume	2.3	2.6	7.1	1.9	2.3	1.7	-0.6	1.2	2.0	1.9	1.3	1.4	1.7	1.0	0.9	1.0	1.6	2.0	0.7	2.7
HbA1C	2.3	2.5	9.2	1.7	1.0	2.3	1.4	0.0	-2.4	2.0	1.3	-0.2	0.8	1.6	1.3	1.5	1.2	1.5	3.0	-0.2
Ulcerative Colitis	2.3	3.3	7.4	-2.3	-1.0	-1.9	0.0	-2.3	0.7	-2.0	-1.6	-1.2	-2.0	-0.7	-1.4	-2.3	-2.7	-2.5	-2.2	-1.3
Alcohol usually taken with meals	2.2	3.5	6.7	1.5	1.7	1.8	1.6	1.5	0.1	1.4	2.1	2.0	2.5	2.3	1.2	2.2	1.5	2.6	1.6	2.6
Pulse rate, automated reading	2.2	7.1	14.0	-2.6	-2.8	-2.7	-1.8	-2.6	0.0	-2.8	-3.7	-2.8	-2.8	-2.2	-2.1	-2.9	-2.9	-3.3	-2.2	-3.0
Medication: Atorvastatin	2.1	2.6	5.5	1.7	1.4	1.3	1.2	2.1	0.7	1.7	2.0	0.7	2.0	1.7	1.3	2.4	2.1	1.7	0.9	1.0
Illnesses of siblings	2.0	2.8	6.3	-1.5	-1.6	-1.7	-2.0	-2.2	1.6	-1.7	-1.2	1.5	-1.0	-0.4	-2.0	-1.6	-1.4	-0.7	-2.2	2.5
Mean time to correctly identify matches	2.0	3.8	7.2	2.1	1.0	2.1	1.8	2.7	-1.4	2.3	2.6	1.9	1.8	0.8	1.1	1.8	2.7	2.4	1.9	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.0	2.4	6.5	2.0	1.4	1.4	2.0	1.7	0.6	2.1	1.4	0.6	0.9	-0.4	1.2	2.5	2.4	1.8	0.7	0.1
Reaction Time	1.9	3.6	6.6	2.1	0.9	2.1	1.3	2.6	-1.1	2.3	2.3	2.2	1.9	1.3	1.0	1.6	2.5	2.6	1.9	1.3
Townsend deprivation index at recruitment	1.9	2.6	5.8	2.3	1.9	2.2	0.6	1.7	-0.3	2.4	-0.1	0.4	1.5	-0.3	1.6	2.0	2.3	1.9	1.7	0.5
Migraine (self-reported)	1.8	2.2	8.0	1.3	1.6	1.0	0.1	1.9	0.3	1.2	2.8	-0.1	2.3	2.0	1.3	1.0	1.5	1.7	0.8	0.9
Gout (self-reported)	1.7	2.3	7.6	-1.8	-1.3	-2.2	-0.3	-1.0	-0.2	-2.1	-0.7	0.4	-2.8	-1.3	-1.7	-1.5	-1.2	-1.7	-1.9	-1.1
Mineral and other dietary supplements	1.7	2.3	4.0	-1.6	-1.4	-1.6	-1.4	-1.9	1.4	-1.6	-1.7	-0.2	-1.6	-1.0	-1.5	-2.0	-2.0	-1.7	-1.6	-0.6
Cholesterol lowering medication	1.7	2.5	4.8	1.9	1.0	1.6	1.9	2.2	-0.3	1.7	1.7	0.9	2.2	1.7	1.5	1.6	1.8	1.6	1.5	0.3
Exposure to tobacco smoke outside home	1.6	2.2	5.2	1.9	2.3	2.0	-0.3	1.8	0.9	1.8	1.6	0.3	1.6	0.7	1.0	1.2	1.6	1.7	1.4	1.2
Age at first live birth	1.6	2.9	7.1	-2.4	-1.7	-2.7	-1.7	-2.1	1.5	-2.6	-0.3	0.9	-2.1	-0.1	-0.6	-0.9	-1.7	-1.3	-2.5	0.5
Supplements: Fish oil (including cod liver oil)	1.6	2.1	4.9	1.5	1.2	1.7	1.8	0.9	-1.4	1.5	1.1	0.0	1.5	1.6	1.5	2.2	1.5	1.7	1.9	0.2
Pain type(s) experienced in last month: Hip pain	1.5	1.9	5.0	1.3	0.8	1.4	2.2	1.3	-1.9	1.4	-0.4	0.5	0.9	1.3	1.3	1.0	1.7	1.4	2.1	-0.7
Medication: Seretide 50 evohaler	1.4	1.6	3.2	-1.7	-1.7	-1.5	-0.5	-1.7	-0.8	-1.8	-1.0	-0.6	-0.8	0.5	-0.5	-1.6	-1.6	-1.5	-0.9	-1.4
Medication: Aspirin	1.4	1.8	4.5	2.1	0.9	1.2	0.8	2.1	1.2	1.9	1.2	-0.1	1.5	0.8	1.2	2.0	1.9	0.9	0.2	0.3
Medication: Blood pressure	1.4	2.6	7.5	2.2	1.6	1.9	1.2	2.7	0.6	2.1	1.5	0.8	2.0	0.7	1.1	1.8	2.0	1.6	1.4	0.5
Alzheimer’s Disease (in father)	1.3	1.4	5.0	1.5	0.2	0.8	1.2	1.9	0.3	1.1	0.3	1.0	0.7	-0.8	1.6	1.8	2.2	1.4	0.7	0.3
Number of treatments/medications taken	1.3	2.3	6.2	2.1	1.1	1.5	0.7	2.5	0.9	1.9	1.3	-0.9	1.8	1.4	1.9	1.6	2.0	1.0	1.0	-0.5
Current tobacco smoking	1.3	2.1	4.4	2.1	0.5	1.7	-0.4	1.6	-0.6	2.0	0.9	-0.7	2.1	1.1	1.6	1.4	1.7	1.2	2.1	-0.8
Smoking status: Previous	1.3	1.9	12.8	-1.6	-0.4	-0.4	0.3	-3.6	-1.1	-1.7	-1.7	0.1	-1.7	0.2	-1.0	-0.4	-2.3	-0.7	-0.0	-0.5
Friendships satisfaction	1.3	1.6	3.1	1.7	1.4	1.7	0.2	0.6	-0.7	1.8	1.6	0.1	0.9	1.3	0.7	1.5	1.4	1.4	1.7	1.0
Smoking status: Current	1.3	2.0	4.1	2.0	0.7	1.7	-0.4	1.8	-0.7	2.0	1.2	-0.5	2.0	1.1	1.5	1.1	1.8	1.2	1.9	-0.4
Ulcerative Colitis (UC)	1.2	2.2	4.9	-2.0	-0.7	-1.8	-1.3	-1.7	1.4	-1.7	-1.6	-0.4	-1.8	-0.1	-1.2	-1.5	-1.8	-1.6	-2.2	-0.6
Frequency of depressed mood in last 2 weeks	1.2	1.7	3.1	-1.5	-1.6	-1.8	0.2	-1.1	0.6	-1.6	-1.1	-1.0	-1.3	-1.2	-0.9	-1.4	-1.4	-1.5	-1.5	-1.6
Depression (self-reported)	1.2	1.4	3.4	-1.0	-0.8	-1.4	-1.1	-0.9	0.8	-1.0	-1.1	-1.2	-1.9	-0.9	-0.8	-0.8	-1.1	-1.6	-1.3	-1.8
Length of working week for main job	1.2	1.4	5.7	1.2	0.7	0.9	2.4	1.2	0.2	0.8	-0.6	1.8	0.2	1.2	0.3	0.6	1.5	1.7	0.6	1.4
Medication: Ventolin 100micrograms inhaler	1.2	1.5	5.9	1.5	0.6	1.6	-0.4	0.1	0.4	1.6	0.2	1.4	1.4	2.4	0.8	0.6	0.8	1.5	1.0	1.5
Chronic bronchitis/emphysema (mother)	1.2	1.4	3.6	-1.5	-1.0	-1.4	-0.9	-1.9	0.1	-1.6	-1.1	-0.2	-1.9	-0.8	-0.6	-1.0	-1.3	-1.4	-1.1	-0.8
Heart disease (siblings)	1.2	1.4	4.3	1.5	1.1	0.8	1.5	2.1	0.1	1.4	0.5	-0.3	1.1	0.3	1.4	1.6	2.0	0.6	0.5	-1.2
Primary Biliary Cirrhosis	1.1	1.5	3.9	1.4	2.0	1.6	1.0	1.6	0.5	1.6	0.6	0.3	1.8	1.0	1.3	1.2	1.1	1.3	0.9	0.4
Heel T-Score	1.1	8.6	31.9	-0.6	4.2	-0.7	3.2	0.7	1.0	-0.7	-2.6	5.7	-1.2	-3.6	-1.3	5.1	1.3	2.7	-1.9	4.7
Impedance of leg (right)	1.1	5.3	17.1	1.7	3.1	1.8	-1.1	1.8	1.4	1.7	3.2	2.8	2.8	1.1	1.1	3.0	1.8	2.7	0.9	4.1
Hayfever, allergic rhinitis or eczema	1.1	2.3	6.6	1.7	1.2	1.8	0.4	0.9	1.1	1.9	1.4	0.7	2.6	1.8	1.7	1.3	1.4	1.9	1.4	1.3
Supplements: Glucosamine	1.1	1.4	3.6	1.1	1.1	0.8	1.5	1.7	-0.4	1.0	0.9	0.1	1.7	0.6	0.8	1.9	1.7	1.4	0.8	0.4
Breastfed as a baby	1.1	1.3	4.4	1.1	0.1	1.5	0.9	1.4	-1.8	1.2	1.2	0.2	1.4	0.9	1.0	0.7	1.0	0.8	2.1	-0.3
Angina (self-reported)	1.1	1.4	3.3	-1.3	-0.9	-1.2	-0.3	-1.3	0.2	-1.5	-0.5	-1.3	-1.8	-1.2	-0.4	-0.6	-1.4	-1.8	-0.8	-1.7
Medication: Ibuprofen	1.1	1.3	10.0	0.9	1.3	1.2	3.2	1.2	-0.7	0.9	-0.2	0.5	0.5	0.7	0.9	-0.1	1.0	1.1	1.2	-0.1
Medication: Aspirin	1.1	1.5	3.8	2.0	0.7	1.4	1.0	1.7	0.6	1.9	1.0	-0.4	1.2	0.6	1.2	1.8	1.6	0.7	0.6	-0.0
Mother’s age at death	1.1	1.4	5.7	1.2	1.3	0.9	-0.5	1.5	1.1	1.3	0.9	1.3	1.2	0.8	0.1	0.9	1.5	1.3	-0.3	2.4
Ever depressed for a whole week	1.1	1.3	6.0	-0.6	-1.4	-0.9	-0.6	-0.5	-1.0	-0.8	-0.6	-2.5	-1.3	-0.5	0.0	-0.9	-0.6	-1.2	-0.3	-2.4
Respiratory disease	1.0	2.3	5.3	2.2	1.0	1.9	-0.7	1.8	0.0	1.9	0.3	0.4	2.3	1.6	1.6	1.6	2.0	1.7	1.5	0.5
Angina	1.0	1.3	3.2	-1.3	-0.9	-1.1	-0.3	-1.2	0.0	-1.5	-0.3	-1.3	-1.7	-1.0	-0.4	-0.5	-1.4	-1.8	-0.6	-1.7
Number of incorrect matches in round	1.0	1.7	5.6	1.4	1.0	1.2	0.1	2.2	0.3	1.3	1.9	0.5	1.5	2.4	1.1	-0.4	1.3	1.2	1.0	1.2
Time employed in main current job	1.0	1.1	5.5	-0.3	-0.9	-0.8	-0.7	0.3	2.3	-0.4	-0.6	-2.2	-0.2	0.4	-0.1	-0.8	-0.6	-1.3	-1.3	-1.3
Worrier / anxious feelings	1.0	1.9	4.5	1.7	1.6	1.0	-0.1	1.4	1.6	1.6	1.8	0.8	0.6	-1.2	0.2	2.1	2.0	1.2	-0.0	1.6
Happiness	1.0	1.2	4.2	1.2	0.9	1.1	-0.1	0.9	-0.9	1.3	2.1	0.7	0.8	1.2	0.7	1.3	1.2	1.0	1.0	1.1
Qualifications: A levels/AS levels or equivalent	1.0	2.1	4.5	-2.0	-1.5	-2.1	-1.0	-1.0	0.0	-2.1	-1.7	-0.1	-1.6	-2.0	-1.1	-1.1	-1.4	-1.5	-1.7	-0.0
Peak expiratory flow (PEF)	1.0	2.2	6.9	1.2	2.6	1.6	2.6	0.8	-0.4	1.2	1.6	0.8	1.1	0.6	0.7	1.8	0.7	1.9	1.4	1.8
Shortness of breath walking on level ground	1.0	1.2	4.5	1.1	0.8	1.3	-0.4	1.1	-1.6	1.1	-0.3	0.5	1.2	2.1	1.1	-0.0	1.1	1.1	1.6	0.0
Qualifications: nursing, teaching	1.0	1.5	3.3	-1.4	-1.3	-1.4	-1.4	-1.1	-0.9	-1.5	-1.8	0.3	-1.5	-0.8	-1.4	-0.9	-1.2	-1.0	-1.3	0.3
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	5.9	-1.1	-2.4	-1.7	-0.8	0.1	-0.3	-1.2	-1.1	-1.5	-0.4	-0.6	-0.5	-1.1	-0.4	-1.6	-0.9	-2.3
Tinnitus: Yes, now most or all of the time	1.0	1.2	3.3	1.6	0.4	1.5	1.3	0.7	0.5	1.8	0.4	-0.0	1.7	0.7	0.2	1.7	1.0	1.1	1.0	0.1
Eye problems/disorders: Glaucoma	1.0	1.2	4.9	-1.0	-0.9	-1.1	-2.2	-0.9	0.7	-1.0	-1.2	-0.5	-1.1	-1.1	-0.5	-1.3	-1.2	-1.4	-1.2	-0.4
Medication: Paracetamol	1.0	1.5	5.2	1.6	1.0	1.3	0.8	1.5	2.3	1.7	1.8	-0.3	1.1	0.1	1.0	0.4	1.2	1.0	0.2	1.0
Alcohol drinker status: Previous	1.0	1.1	3.2	-0.9	-0.8	-1.0	-1.8	-0.4	0.8	-0.9	-0.8	-1.7	-0.7	-1.4	-0.8	-0.5	-1.0	-1.4	-1.0	-0.8
Waist Hip Ratio (WHR)	0.9	4.0	8.5	2.6	1.8	2.5	-0.4	2.7	-0.1	2.4	2.3	-0.2	2.9	1.2	2.1	1.9	2.0	2.1	2.5	0.8
Serious illness, injury or assault to yourself	0.9	1.0	3.6	1.0	1.2	0.8	0.4	1.9	0.4	0.8	0.7	-1.8	0.9	-0.2	1.1	1.0	0.9	0.2	0.7	-1.5
High blood pressure (mother)	0.9	1.3	3.1	1.4	1.8	1.5	1.3	1.2	0.3	1.5	0.8	1.0	0.9	-0.9	1.0	0.7	1.3	1.2	1.0	0.7
Waist circumference	0.9	3.3	13.2	2.0	0.8	2.2	3.6	1.5	-2.1	1.9	-0.4	-0.6	0.9	1.9	1.2	1.1	1.7	1.4	2.5	-2.1
Past tobacco smoking	0.9	1.6	10.2	1.2	0.9	0.4	0.2	3.2	1.1	1.3	1.7	0.5	1.6	0.0	0.6	0.7	1.9	0.8	-0.0	1.0
Had menopause	0.9	1.2	3.8	-0.8	-1.4	-0.6	-0.0	0.3	-2.0	-1.1	-0.2	-0.8	-1.3	-1.6	-0.7	-1.1	-0.6	-1.2	0.3	-1.9
Financial difficulties in last 2 years	0.9	1.2	5.5	-0.3	-0.9	-0.2	-0.8	-0.6	-1.6	-0.4	-2.1	-1.5	-0.8	-0.1	-0.0	-0.7	-0.4	-0.8	0.8	-2.4
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	3.1	1.4	1.2	1.0	-1.7	1.4	0.4	1.3	0.9	-0.4	0.8	-0.2	0.7	1.8	1.3	0.5	0.3	0.4
Leg pain on walking	0.9	1.1	5.3	1.0	0.2	0.9	0.5	1.0	-1.3	1.1	-0.1	-2.3	0.6	-0.3	0.6	0.4	0.6	-0.1	1.2	-2.2
Hypertension (Self-reported)	0.9	2.5	6.7	1.6	1.5	1.7	2.5	2.6	-0.5	1.5	0.6	-0.5	1.4	0.9	1.4	1.8	1.6	0.7	1.8	-2.0
Average weekly champagne plus white wine intake	0.9	1.2	4.3	0.6	0.6	0.2	0.9	1.6	0.5	0.6	2.1	1.3	1.3	1.2	0.9	0.3	1.1	1.3	-0.1	1.6
Irritability	0.9	1.6	5.5	-1.4	-0.5	-1.8	-1.7	-1.0	0.5	-1.6	-0.6	-1.0	-1.3	-2.3	-0.8	0.0	-1.1	-1.3	-1.4	-0.8
Commuting to job workplace: Cycle	0.9	1.0	5.5	0.1	-0.1	-0.5	-0.2	1.4	0.4	0.1	0.6	2.3	0.8	-1.0	0.2	-0.1	1.0	1.1	-0.9	2.1
Cardiovascular Disease	0.8	2.8	11.4	1.8	2.0	1.6	2.3	2.1	1.0	1.6	1.1	-0.2	1.3	0.9	1.4	3.4	1.7	1.2	1.2	-0.9
Supplements: Zinc	0.8	0.9	4.9	0.2	-0.8	-0.5	-2.2	0.8	0.2	0.2	-1.3	-1.4	0.4	-0.2	0.4	-0.1	0.6	-0.9	-0.3	-1.8
High blood pressure	0.8	2.3	7.8	1.3	1.2	1.5	2.8	2.4	-1.0	1.3	0.4	-0.6	1.2	0.9	1.1	1.4	1.4	0.5	1.8	-2.4
Number of live births	0.8	1.2	5.6	0.8	-0.2	1.1	1.4	0.7	-2.4	0.9	0.7	-0.2	1.0	0.6	0.9	0.6	0.7	0.6	1.9	-1.1
Financial situation satisfaction	0.8	1.0	2.3	-1.0	-0.5	-0.8	-1.4	-1.1	-0.3	-1.1	-0.6	-1.3	-1.3	-0.8	-0.9	-0.7	-1.3	-1.5	-0.7	-1.1
High cholesterol (Self-reported)	0.8	1.4	5.0	1.4	0.5	1.0	2.2	1.1	0.6	1.0	1.1	1.3	0.3	0.5	0.6	2.2	1.6	1.2	0.4	0.7
Vascular/heart problems diagnosed by doctor	0.8	2.2	7.4	-1.4	-1.1	-1.5	-2.7	-2.2	0.9	-1.4	-0.4	0.8	-1.0	-0.7	-1.2	-1.5	-1.4	-0.3	-1.6	2.6
Basal cell carcinoma (self-reported)	0.8	0.9	3.1	-0.9	-0.8	-0.7	-1.6	-1.2	-1.8	-0.8	-0.5	-1.0	-0.9	0.1	-0.5	-0.9	-1.2	-1.0	0.2	-0.5
Prostate Cancer	0.7	0.9	7.0	-0.6	-0.4	-0.6	-2.6	0.5	0.1	-0.7	0.2	0.7	-0.7	-0.5	-0.8	-1.7	-0.6	-0.5	-0.4	1.1
Lupus	0.7	1.0	2.8	1.1	1.4	1.2	-0.2	1.3	0.6	1.3	1.7	0.6	1.2	0.4	-0.4	0.6	0.8	1.0	0.3	1.4
Hearing difficulty/problems: Yes	0.7	1.1	6.6	0.8	0.7	1.1	2.6	0.7	-1.9	0.8	-0.5	0.5	0.0	-0.9	0.1	0.0	0.9	1.0	1.5	-0.5
Qualifications: CSEs or equivalent	0.7	0.9	2.3	1.4	0.4	1.2	-0.0	0.9	0.2	1.2	1.2	-0.8	1.0	-0.5	0.8	0.9	1.2	0.9	1.5	-0.8
Impedance of leg (left)	0.7	3.5	14.1	1.0	2.7	1.1	-1.7	1.1	1.9	1.0	2.4	2.4	2.1	0.3	0.4	2.6	1.0	1.9	0.2	3.8
Had other major operations	0.7	0.9	3.7	-0.5	-1.1	-0.9	-1.6	0.3	-0.3	-0.5	-1.9	-0.9	-0.2	-1.1	0.0	-0.6	-0.2	-0.7	-0.8	-1.4
Heart attack	0.7	0.9	4.2	-0.4	-0.4	-0.5	-0.2	-1.3	2.1	-0.3	-1.3	-1.3	-0.8	-0.2	-0.7	0.3	-0.7	-0.9	-1.4	-0.4
Allergy	0.7	1.7	5.4	-1.6	-0.6	-1.4	-0.2	-1.4	-0.4	-1.6	-0.2	-0.8	-2.3	-1.8	-1.2	-0.8	-1.5	-1.7	-1.3	-0.6
Pain all over the body in last month	0.7	0.7	5.1	0.1	0.4	1.1	1.1	-1.0	-2.3	0.1	0.1	0.5	-0.2	0.6	-0.3	0.5	-0.5	0.4	1.6	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	7.8	-0.1	0.2	0.1	2.8	0.5	-1.1	-0.2	-1.5	-0.2	-0.6	0.1	0.6	-0.9	0.3	0.1	0.5	-1.2
Tense / ‘highly strung’	0.7	1.2	4.7	-0.3	-0.6	-0.8	-2.2	-0.2	1.6	-0.4	1.6	-1.5	-1.0	-1.3	-0.2	-0.4	-0.5	-1.4	-0.9	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	4.4	-0.8	-0.6	-0.9	-2.1	-1.4	1.4	-0.9	-0.9	-0.7	-1.1	-0.9	-0.5	-0.1	-1.0	-1.0	-1.1	-0.9
High blood pressure (siblings)	0.7	1.1	6.9	0.3	0.1	0.4	1.4	0.4	-0.9	0.6	-0.2	-1.8	-0.2	-0.4	1.1	1.4	0.2	-0.3	1.2	-2.6
Worry too long after embarrassment	0.7	1.2	4.2	-1.3	0.1	-1.2	1.6	-0.6	0.8	-1.2	-0.5	-0.1	-1.1	-2.0	-1.2	-0.3	-1.2	-1.0	-1.2	-0.1
Heart disease (mother)	0.7	0.9	2.5	-1.1	-1.4	-1.2	-0.7	0.6	-1.3	-1.3	-0.3	-0.3	-1.0	-0.6	-0.3	-0.6	-0.4	-1.0	-0.2	-1.6
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.4	-1.2	-0.8	-0.9	-0.4	0.1	0.2	-1.1	0.0	-1.0	-0.8	-0.4	-1.0	-1.5	-1.0	-1.0	-0.6	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	4.2	1.1	1.6	1.1	0.7	1.5	-0.1	1.1	1.7	0.6	1.1	-0.2	0.4	1.8	1.2	2.0	1.0	1.1
Loneliness, isolation	0.7	1.0	3.2	-0.3	-1.6	-0.9	-0.5	-0.5	1.8	-0.5	-1.5	-0.4	-0.7	-1.2	-1.0	-1.3	-0.4	-0.5	-1.3	-0.1
Osteoarthritis (self-reported)	0.7	0.8	4.3	-0.4	-0.9	-0.6	-0.0	-0.4	-0.4	-0.2	-2.1	-1.1	-0.2	-1.1	-0.2	-1.0	-0.2	-1.1	-0.8	-1.8
Guilty feelings	0.7	1.0	4.1	-0.8	-0.6	-1.1	-0.5	-0.5	0.1	-0.8	-0.9	-1.1	-1.3	-2.0	-0.9	-0.1	-0.6	-1.2	-0.9	-1.7
Hearing aid user	0.7	0.8	2.1	-0.8	-1.1	-0.4	0.8	-1.3	-0.5	-0.6	-1.3	-0.9	-0.9	0.1	-0.3	-1.5	-1.2	-1.0	-0.1	-1.0
Diastolic blood pressure, automated reading	0.7	2.1	5.4	1.6	1.3	1.7	1.1	2.3	-0.2	1.6	1.6	-0.6	1.8	0.2	1.2	2.3	1.7	1.1	1.4	-1.1
HDL Cholesterol	0.6	1.0	5.1	-0.2	-0.5	-0.4	-1.6	-0.1	1.8	-0.1	0.9	-2.2	0.2	-1.3	-0.1	-0.5	-0.6	-1.2	-0.4	-0.4
Maternal smoking around birth	0.6	0.9	3.8	-0.3	-0.1	0.6	0.7	-1.9	-0.2	0.0	-0.5	-1.4	-1.1	-1.2	-0.5	-0.2	-1.5	-0.5	0.8	-1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	4.8	-0.2	-0.2	-0.9	1.4	1.4	-0.5	-0.5	-1.7	2.1	-0.1	-2.2	0.1	2.0	1.2	1.0	-0.7	0.1
Nervous feelings	0.6	1.1	7.3	0.3	1.0	-0.2	-0.8	0.8	2.7	0.2	1.6	0.9	0.3	-1.0	0.5	0.7	0.6	0.4	-1.0	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	2.4	1.2	1.2	1.0	1.6	1.3	0.1	1.2	-0.2	0.3	1.1	0.4	0.6	1.3	1.5	1.2	0.8	-0.6
Birth weight of first child	0.6	1.0	4.4	-0.9	-1.6	-0.7	-1.0	-1.5	-2.1	-0.7	0.3	-0.0	-0.5	1.4	-0.1	-0.8	-1.1	-0.8	0.4	-0.5
Leg fat percentage (right)	0.6	2.2	13.9	1.7	1.4	1.8	3.7	1.1	0.3	1.5	-0.4	0.4	0.6	0.9	0.8	1.8	1.6	1.4	1.4	-0.6
Comparative body size at age 10	0.6	1.5	16.0	0.9	1.0	1.0	4.0	-0.7	0.2	0.8	-1.4	-0.1	-0.3	-0.4	0.1	1.6	0.4	0.6	0.5	-0.5
Wheeze or whistling in the chest in last year	0.6	1.1	2.7	1.1	0.7	0.7	0.7	1.1	1.1	1.2	-0.1	1.4	1.4	-0.0	0.7	1.5	1.4	1.6	0.1	0.7
Medication for pain relief, constipation, heartburn	0.6	1.1	3.5	-1.4	-0.3	-0.8	-1.9	-1.6	-0.9	-1.3	-0.2	0.5	-1.0	-0.7	-1.3	-0.6	-1.3	-0.7	-0.5	0.5
Chest pain or discomfort	0.6	0.9	3.0	1.0	0.5	0.6	-0.6	1.7	-0.5	0.8	-0.6	0.6	1.3	1.0	0.9	0.7	1.5	1.2	0.6	0.3
Illnesses of father: Heart disease	0.6	0.9	2.8	0.6	0.8	0.2	1.4	0.4	-0.6	0.5	1.7	0.5	0.4	0.9	0.8	1.7	1.2	1.1	0.6	0.3
Commuting to job workplace: Walk	0.6	0.7	4.1	0.5	0.3	0.3	-0.4	-0.2	-0.9	0.2	-0.2	1.6	0.2	-0.1	0.3	0.7	0.8	1.4	0.5	2.0
Asthma (self-reported)	0.6	1.3	3.2	1.4	0.7	1.5	0.0	1.1	0.0	1.4	0.2	0.8	1.8	1.7	1.0	1.3	1.1	1.3	1.0	0.5
Wears glasses or contact lenses	0.6	0.7	2.7	0.6	-0.5	0.4	-1.6	0.7	0.4	0.7	0.9	-1.4	0.8	1.6	0.9	0.2	0.4	-0.2	0.4	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	4.4	-0.1	-0.9	-0.3	-0.2	-0.3	0.0	-0.1	-0.8	-2.1	0.3	0.7	0.2	-0.9	-0.3	-0.5	0.2	-1.8
Impedance of whole body	0.6	3.1	13.7	0.7	2.1	0.7	-1.7	1.4	1.8	0.7	2.5	2.7	2.1	0.0	0.3	2.0	0.9	1.7	-0.2	3.7
Worry (Nagel 2018)	0.5	1.0	3.3	1.3	0.9	0.7	-1.2	0.8	1.8	1.2	1.4	-0.4	0.3	-1.3	0.5	1.2	1.0	0.3	0.1	0.3
Alzheimer’s Disease (in mother)	0.5	0.6	1.8	-0.5	-1.0	-1.1	-1.3	-0.4	0.9	-0.8	-1.0	1.1	-0.6	-0.9	-0.3	0.4	0.1	0.1	-0.9	0.7
Alzheimer’s Disease (including proxy)	0.5	0.8	4.0	0.0	-0.3	-0.8	0.1	0.7	0.6	-0.4	-0.7	2.0	0.0	-1.0	0.2	1.6	1.2	0.8	-0.7	1.2
Age at First Birth	0.5	0.7	2.1	-1.0	-0.4	-0.8	-1.4	-1.2	0.3	-1.1	-0.3	-0.4	-1.0	-0.2	-0.2	-0.5	-1.1	-0.9	-1.0	-0.1
Crohns Disease (2012)	0.5	0.7	2.5	0.8	1.0	0.9	-0.0	0.2	-0.5	0.9	0.6	0.4	0.8	1.2	1.6	1.3	0.8	0.9	0.8	0.5
Sensitivity / hurt feelings	0.5	0.8	1.9	-0.8	0.4	-0.4	-0.4	-1.0	0.6	-0.8	0.0	-0.7	-1.2	-0.9	-1.4	-1.2	-1.3	-1.1	-0.9	-1.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	3.1	0.1	-0.9	-0.6	-1.2	0.8	-0.2	-0.0	-0.6	-1.4	-0.4	-1.4	-0.3	-0.1	0.3	-0.8	-0.3	-1.8
Systolic blood pressure, automated reading	0.5	1.3	7.8	0.5	-0.1	0.6	1.8	1.6	-0.3	0.6	0.6	-2.0	0.8	0.1	1.2	0.6	0.6	-0.4	0.8	-2.8
Average weekly fortified wine intake	0.5	0.6	2.9	0.8	0.7	0.6	0.5	1.4	-0.2	1.0	1.7	-0.5	1.3	0.3	0.5	0.1	0.7	0.1	0.2	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.5	1.0	1.0	0.7	0.7	1.2	0.9	1.0	0.3	0.2	1.1	-0.4	0.6	1.1	1.1	1.1	0.6	0.2
Taking other prescription medications	0.5	0.8	3.6	-0.6	-0.8	-0.4	-1.1	-0.7	-0.2	-0.5	-0.8	-1.2	-0.4	1.9	-0.2	-1.0	-1.1	-1.1	-0.2	-1.3
Body mass index (BMI)	0.5	1.9	15.7	0.7	-0.1	0.8	4.0	-0.1	-0.9	0.5	-1.7	-1.4	-0.7	0.4	0.1	0.2	0.4	-0.2	1.1	-2.9
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	4.8	-0.1	0.2	-0.5	1.1	1.0	-0.5	-0.3	-1.4	1.9	-0.3	-2.2	0.1	2.0	1.1	1.0	-0.6	0.4
Qualifications: None of the above	0.5	1.0	3.1	1.4	0.8	1.6	1.3	0.6	-0.1	1.5	0.1	-1.8	0.9	-0.2	0.3	0.1	0.6	0.2	1.4	-0.8
Fluid intelligence score	0.5	0.9	4.1	-1.2	-1.1	-1.4	-0.9	-0.4	0.3	-1.5	-0.4	2.0	-0.9	0.1	-0.5	-0.7	-0.5	0.0	-1.0	1.0
Hip circumference	0.5	2.0	16.5	0.6	0.3	0.9	4.1	0.3	-1.7	0.7	-1.2	-0.9	-0.3	1.3	0.3	0.3	0.7	0.4	1.4	-2.4
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	5.2	0.9	2.1	0.9	1.7	0.5	-0.1	0.9	1.7	1.0	0.8	-0.8	0.7	1.3	0.9	1.9	0.5	2.3
Noisy workplace	0.5	0.6	3.2	-0.5	-0.9	-0.1	0.0	-0.4	-0.4	-0.3	-0.7	-1.8	-0.1	0.5	-0.4	-0.0	-0.7	-0.8	0.3	-1.8
Mouth/teeth dental problems: Dentures	0.5	0.8	3.2	0.7	-0.6	0.7	0.8	0.6	-1.3	0.6	0.5	-1.3	0.4	1.7	0.8	0.1	0.4	-0.1	1.2	-1.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	4.2	1.2	2.0	1.2	1.7	0.7	-0.5	1.2	1.4	0.7	1.0	-0.2	1.0	1.1	1.1	2.1	0.9	2.0
Hair/balding pattern: Pattern 4	0.5	1.1	4.9	0.8	2.2	0.7	-0.0	1.1	1.8	1.0	0.4	1.4	0.3	-0.7	0.2	1.4	1.0	0.5	-0.6	1.3
Blood clot in the leg (DVT)	0.5	0.6	2.0	-0.4	-1.4	-0.5	-1.2	-0.5	-0.1	-0.6	-1.4	0.2	-0.7	-0.6	-0.6	-1.0	-0.2	-0.6	-0.6	-0.8
Headache pain in last month	0.5	0.9	3.2	1.2	0.3	0.7	-0.6	1.8	0.8	1.1	1.2	-0.1	1.4	0.3	0.3	0.2	1.2	1.0	0.6	0.8
Birth weight	0.5	1.0	3.2	-1.1	0.2	-1.0	-1.8	-1.0	0.9	-0.8	-1.3	0.5	-0.4	-0.5	-1.0	-0.6	-1.0	-0.6	-1.4	1.5
Health satisfaction	0.5	0.6	2.1	0.7	-0.7	-0.2	-1.3	1.1	0.6	0.7	0.7	-1.4	0.7	-0.3	0.5	-1.0	0.7	-0.4	-0.5	-0.9
Leg fat mass (right)	0.5	1.9	17.2	1.1	1.2	1.4	4.2	0.5	-0.9	0.9	-1.0	-0.1	-0.1	1.0	0.5	0.8	0.9	1.0	1.4	-1.3
Suffer from ‘nerves’	0.5	0.8	3.9	0.0	0.4	-0.2	-0.9	-0.5	2.0	-0.2	0.1	1.0	-1.0	-1.8	-0.5	0.2	-0.2	0.2	-0.8	1.1
Age at last live birth	0.5	0.7	2.7	-0.9	-1.0	-1.0	0.6	-1.3	-0.1	-1.0	0.6	1.6	-1.0	1.0	0.4	0.2	-0.4	-0.0	-0.8	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.8	0.4	0.9	0.9	0.2	-0.2	-1.1	0.6	0.4	0.2	0.4	1.7	0.5	1.1	0.4	0.4	1.1	-0.3
Knee pain experienced in last month	0.5	0.8	1.8	1.0	0.2	0.9	1.0	1.0	-1.3	1.1	-0.5	0.0	0.5	-0.3	0.4	0.9	1.2	0.5	1.2	-1.4
Leg fat-free mass (right)	0.5	2.6	8.4	-1.1	-1.3	-0.7	2.5	-1.0	-2.8	-1.1	-2.1	-1.4	-2.0	-0.2	-0.7	-1.8	-1.1	-0.9	0.5	-2.9
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.7	-0.3	-0.5	-0.7	1.0	-0.2	-0.1	-0.4	-1.4	1.6	-0.5	-0.6	-0.3	-0.9	-0.0	0.1	-1.0	0.2
Leg predicted mass (right)	0.5	2.5	8.1	-1.1	-1.2	-0.7	2.5	-1.0	-2.8	-1.1	-2.1	-1.3	-2.0	-0.1	-0.7	-1.7	-1.1	-0.8	0.5	-2.8
Arm fat mass (left)	0.5	1.9	19.7	0.7	0.4	0.9	4.4	0.1	-1.1	0.6	-1.6	-0.3	-0.5	0.7	0.3	0.3	0.6	0.5	1.1	-2.0
Number of self-reported non-cancer illnesses	0.5	0.9	2.9	1.4	0.4	0.8	-1.0	1.2	0.5	1.3	-0.5	-0.5	0.5	-0.2	0.9	1.7	1.6	0.5	-0.1	-0.5
Miserableness	0.5	0.9	3.2	-0.8	0.1	-1.1	1.8	-0.9	1.6	-0.9	-0.4	0.1	-1.0	-1.1	-1.1	0.4	-0.5	-0.1	-1.5	-0.2
Risk taking	0.5	0.7	3.5	0.0	-1.3	-0.2	-0.3	0.5	-1.9	-0.1	-1.1	-0.1	0.2	1.1	0.5	-1.4	0.3	-0.1	0.7	-1.0
Age started oral contraceptive pill	0.5	0.7	1.5	-1.1	-0.9	-0.8	1.1	-0.7	-1.2	-1.1	-0.1	-0.3	-0.8	-0.2	-0.5	-0.5	-1.1	-0.9	-0.5	-0.5
Unable to work because of sickness or disability	0.5	0.6	2.8	1.0	0.0	0.6	-0.0	1.7	0.2	0.9	-0.3	-0.9	1.2	-0.6	0.2	-0.4	0.7	0.2	0.5	-1.3
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.9	-0.3	-0.4	-0.4	-0.1	-1.0	1.7	-0.2	-1.2	-1.4	-0.7	-0.0	-0.5	0.1	-0.6	-0.8	-1.1	-0.6
Bipolar Disorder (2018)	0.4	0.6	2.0	-0.4	0.3	-0.9	-0.1	1.2	1.1	-0.6	-0.5	0.8	-0.4	-0.9	-1.4	-0.7	0.1	-0.1	-1.2	0.7
Body Mass Index (BMI) (2010)	0.4	0.6	4.8	0.5	0.4	0.5	2.2	-0.2	-0.5	0.5	-0.3	-1.2	-0.1	0.5	0.2	0.7	0.0	0.0	0.4	-1.4
Rheumatoid Arthritis	0.4	0.6	3.6	0.2	-0.5	0.1	0.7	-0.4	-1.9	0.3	0.2	-0.9	0.1	-0.6	0.4	1.3	0.3	0.1	0.9	-1.1
Type 2 Diabetes (T2D) (2012)	0.4	0.5	3.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.8	1.0	1.3	1.2	0.6
Blood Platelet Count	0.4	5.1	16.6	2.4	0.1	2.7	-0.9	1.0	-3.9	2.5	-2.3	-0.7	2.8	2.6	1.2	2.2	1.6	1.8	4.1	-1.2
Smoking Status	0.4	1.0	4.3	0.9	1.0	1.3	0.6	-0.5	-1.7	0.7	-0.1	-0.4	0.7	1.1	0.9	0.8	0.3	0.7	2.1	-1.0
Lung FEV1/FVC ratio	0.4	1.9	7.2	1.5	2.7	1.7	1.5	0.8	0.3	1.2	2.1	1.2	0.4	-0.3	0.1	1.3	1.2	1.7	0.9	1.7
Lung FVC	0.4	2.0	3.9	-1.3	-1.7	-1.7	-1.5	-1.8	-0.3	-1.4	-1.0	-2.0	-1.3	-2.0	-0.4	-0.5	-1.3	-1.9	-1.2	-1.2
Ever had hysterectomy (womb removed)	0.4	0.4	1.6	0.7	0.6	0.6	0.8	1.3	0.2	0.7	0.2	-0.2	0.8	-0.5	0.5	0.7	0.8	0.4	0.3	-0.5
Severe depression (siblings)	0.4	0.4	1.6	0.1	-1.3	0.0	-1.2	-0.7	-1.1	0.1	-0.9	-0.7	-0.3	0.6	-0.0	0.1	-0.1	-0.2	0.2	-1.0
Leg fat-free mass (left)	0.4	2.1	10.0	-0.7	-0.8	-0.3	3.2	-0.6	-3.0	-0.7	-1.7	-0.9	-1.6	0.3	-0.3	-1.3	-0.6	-0.3	0.9	-2.5
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	3.7	0.0	-0.3	0.3	-0.9	-0.6	-1.0	0.0	-0.2	0.8	0.8	1.9	0.2	0.1	-0.4	0.4	0.5	0.8
Chronic bronchitis/emphysema (father)	0.4	0.4	1.5	1.1	0.2	0.7	-1.0	1.2	0.1	1.1	0.1	-0.2	0.7	0.2	0.6	-0.5	0.9	0.2	0.4	0.2
Leg predicted mass (left)	0.4	2.1	9.8	-0.7	-0.7	-0.3	3.1	-0.6	-3.0	-0.6	-1.7	-1.0	-1.5	0.3	-0.3	-1.3	-0.6	-0.3	0.9	-2.5
Trunk fat mass	0.4	1.6	17.8	0.6	1.0	0.9	4.2	0.5	-1.0	0.4	-1.0	0.4	-0.5	0.3	-0.1	0.7	0.6	0.7	0.9	-1.2
Mouth/teeth dental problems	0.4	0.6	2.5	-0.2	1.2	0.3	-1.0	-0.7	1.3	-0.1	0.4	0.3	-0.4	-0.6	-1.0	-0.3	-0.8	0.2	-0.6	1.6
Neuroticism score	0.4	0.9	3.8	-0.6	-0.2	-1.1	-0.5	-0.5	2.0	-0.7	-0.1	-0.6	-1.0	-1.9	-0.7	0.2	-0.4	-0.7	-1.5	-0.6
Weight	0.4	2.1	16.5	0.3	0.4	0.8	4.1	0.1	-2.5	0.3	-1.4	-0.7	-0.7	0.9	0.1	0.1	0.2	0.5	1.6	-2.2
Arm fat percentage (right)	0.4	1.5	15.4	0.8	0.1	0.8	3.9	0.2	-0.3	0.5	-1.5	-0.2	-0.3	0.2	0.4	0.4	0.6	0.3	0.8	-1.9
Father’s age at death	0.4	0.5	3.2	-0.5	0.6	-0.1	0.5	-0.5	0.6	-0.3	0.1	1.2	0.3	1.4	-0.2	0.0	-0.5	0.3	-0.8	1.8
Prospective memory result	0.4	0.5	3.2	0.3	0.7	0.2	-0.1	-0.2	0.3	0.4	1.1	1.8	-0.3	-0.8	-0.3	-0.2	0.2	0.3	-0.1	1.7
Lung cancer (father)	0.4	0.4	1.9	0.5	0.0	0.8	-0.2	0.3	-1.4	0.3	0.4	-0.2	0.2	-0.0	0.8	-0.7	0.2	0.3	1.4	-1.0
Pulse wave Arterial Stiffness index	0.4	0.5	2.8	0.2	0.5	0.5	-0.6	0.3	-0.2	0.4	-0.2	-1.6	-0.1	-0.2	-0.5	-0.8	-0.3	-0.6	0.5	-1.7
Impedance of arm (left)	0.4	1.7	7.0	0.7	1.2	0.5	-1.3	1.4	0.9	0.6	1.7	2.3	1.7	-0.0	0.5	1.2	0.9	1.4	0.1	2.6
Arm fat mass (right)	0.4	1.8	17.1	0.7	0.3	1.0	4.1	0.1	-1.2	0.6	-1.5	-0.4	-0.4	0.6	0.4	0.3	0.5	0.5	1.2	-2.1
Exposure to tobacco smoke at home	0.4	0.5	3.9	0.3	0.2	-0.2	-1.1	1.0	2.0	0.3	-0.7	-0.2	0.2	0.0	0.3	-0.1	0.6	-0.3	-0.6	-0.2
Pulse wave reflection index	0.4	0.5	1.0	0.7	1.0	1.0	0.1	1.0	-0.3	0.8	1.0	-0.0	0.7	0.8	0.1	0.6	0.5	0.5	0.9	-0.5
Loud music exposure frequency	0.4	0.4	1.5	-0.7	-0.1	-0.8	-0.5	-0.1	-1.2	-0.8	-1.2	0.7	-0.3	-1.1	0.1	0.4	-0.1	-0.3	0.0	-0.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.9	0.5	0.2	0.6	1.3	-0.4	-0.7	0.5	0.1	1.4	-0.3	-0.3	0.3	0.5	0.8	0.8	0.8	0.9
Body fat percentage	0.4	1.6	16.8	1.0	1.1	1.1	4.1	0.8	-0.1	0.7	-1.1	0.5	-0.1	0.2	0.2	1.1	0.9	0.8	0.9	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.9	-0.6	-1.4	-0.9	-0.6	-0.5	0.3	-0.6	-0.6	-0.9	-0.4	0.5	-0.7	-0.2	-0.6	-0.9	-0.5	-1.1
Qualifications: College or University degree	0.4	1.1	3.5	-1.4	-1.7	-1.9	-1.0	-0.1	-0.0	-1.5	-0.1	1.4	-0.5	-0.5	-0.1	-0.9	-0.5	-0.1	-1.5	1.3
Medication: Blood pressure	0.4	0.7	3.0	-0.3	0.7	-0.1	1.3	0.6	-0.9	-0.4	-1.0	-0.8	-1.1	-1.2	0.2	-0.3	-0.2	-0.7	0.0	-1.7
Whole body fat mass	0.4	1.8	19.4	0.8	0.9	1.1	4.4	0.5	-1.1	0.6	-1.3	0.1	-0.3	0.6	0.2	0.6	0.7	0.7	1.2	-1.6
Had major operations	0.4	0.4	1.8	-0.1	-0.6	-0.3	-0.9	0.2	-0.9	-0.3	-1.3	-0.6	-0.6	-0.7	-0.2	-0.7	-0.1	-0.6	0.2	-1.2
Arm fat percentage (left)	0.4	1.6	17.5	1.0	0.4	1.0	4.2	0.5	-0.1	0.7	-1.4	0.0	-0.3	0.2	0.4	0.6	0.9	0.5	0.8	-1.8
Average weekly red wine intake	0.4	0.6	2.9	-0.1	0.1	0.7	1.3	-0.8	-1.1	0.1	-1.7	-0.5	0.3	1.5	-0.1	0.4	-0.5	0.3	0.7	-0.4
Eye problems/disorders: Cataract	0.4	0.5	2.1	-0.1	1.3	0.4	0.5	0.3	-1.5	0.3	1.0	-1.2	0.3	0.1	-0.4	0.5	-0.4	-0.1	0.6	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.5	-0.4	-0.1	-0.7	-0.9	0.2	0.8	-0.6	-1.2	1.1	0.1	-0.0	-0.6	-0.4	-0.1	0.2	-1.2	1.1
Osteoporosis (self-reported)	0.4	0.5	1.7	0.1	-0.6	0.1	-1.2	-0.3	-0.2	0.1	0.1	-1.3	0.5	0.8	1.1	-1.0	-0.2	-0.8	0.4	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.2	-0.7	-1.1	-0.8	-0.3	-1.3	-1.0	-0.9	-0.2	-1.3	-1.1	-1.5	-0.5	-1.3	-0.9	-0.9	-0.4	-0.8
Whole body water mass	0.4	2.0	11.4	-0.5	-0.5	0.1	2.8	-0.6	-3.4	-0.4	-1.4	-1.1	-1.1	1.0	-0.2	-1.0	-0.5	-0.0	1.4	-2.3
Basal metabolic rate	0.4	2.0	10.1	-0.3	-0.4	0.2	3.1	-0.5	-3.2	-0.3	-1.5	-1.0	-1.1	0.9	-0.1	-0.8	-0.4	0.0	1.4	-2.4
Leg fat percentage (left)	0.4	1.3	11.2	1.1	1.1	1.2	3.3	0.6	0.5	0.9	-0.9	0.2	-0.1	0.3	0.3	1.3	1.0	0.8	0.8	-1.0
Number of operations (self-reported)	0.4	0.6	3.2	-0.3	-0.2	-0.4	0.3	-0.1	-1.3	-0.3	-1.8	-0.3	-0.4	-1.3	-0.1	0.3	-0.2	-0.6	-0.1	-1.4
Average weekly beer plus cider intake	0.4	0.6	1.9	-0.8	-1.4	-0.8	0.5	-1.4	0.1	-0.7	-0.2	-0.3	-0.7	0.0	-0.4	-0.9	-1.0	-0.8	-0.6	-0.7
Fractured/broken bones in last 5 years	0.4	0.6	1.9	0.9	0.3	0.4	1.4	0.6	0.1	1.1	1.3	1.0	0.8	0.3	0.6	-0.0	1.0	0.7	0.0	0.4
Pack years of smoking	0.4	0.6	4.0	0.4	-0.0	0.3	-0.3	0.8	0.3	0.6	-0.5	-1.9	0.1	-0.1	-0.0	-0.5	-0.2	-1.0	0.2	-2.0
Leg fat mass (left)	0.4	1.5	15.5	0.7	1.0	1.0	3.9	0.3	-0.7	0.5	-1.1	-0.1	-0.5	0.6	0.2	0.7	0.5	0.6	1.1	-1.4
Arm predicted mass (left)	0.4	1.8	10.3	-0.1	0.0	0.5	2.9	-0.4	-3.2	0.1	-1.2	-1.1	-0.8	1.1	-0.2	-0.4	-0.3	0.2	1.6	-2.1
Intelligence (Savage-Jansen 2018)	0.3	0.9	2.9	-1.1	-1.1	-1.4	-0.0	-0.6	-0.1	-1.4	-0.5	1.7	-0.5	1.0	-0.5	0.4	-0.4	-0.2	-1.4	1.2
Schizophrenia (2018)	0.3	0.7	4.0	0.4	0.8	0.9	-1.1	0.1	0.5	0.5	0.8	0.4	0.6	2.0	1.3	-0.1	0.1	0.3	0.8	0.4
Irritable Bowel Disease (IBD)	0.3	0.8	2.3	-0.9	0.0	-1.0	-1.3	-1.2	1.2	-0.7	-1.0	-0.5	-1.2	-0.1	-0.2	-0.2	-0.6	-0.9	-1.5	-0.4
Ovarian Cancer	0.3	0.4	2.8	-0.3	-0.6	0.0	-0.7	-0.7	-0.4	-0.1	0.2	-1.7	-0.1	0.8	0.1	-0.5	-0.6	-0.7	0.4	-0.9
Triglycerides	0.3	0.5	3.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.2	1.7	1.5	1.5	0.0	1.2
BMI	0.3	2.0	16.5	0.4	0.3	0.8	4.1	-0.6	-1.2	0.3	-1.3	-1.5	-1.0	-0.1	0.1	0.1	-0.2	0.1	1.3	-2.8
Hypothyroidism (self reported)	0.3	0.8	4.1	0.8	0.3	0.3	-1.8	-0.1	2.0	0.8	-0.0	-0.5	-0.1	-0.6	0.1	1.6	0.7	-0.1	-0.6	0.4
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.2	1.1	0.1	0.7	-0.0	1.1	-0.1	1.0	0.8	-0.1	0.8	0.2	0.4	0.0	0.9	0.6	0.6	-0.2
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.7	-0.1	-0.3	0.1	-1.0	0.8	-1.3	0.1	0.5	-0.8	0.3	0.3	0.1	-0.3	-0.3	-0.3	0.6	-0.8
Medication for hormone replacement therapy	0.3	0.4	1.2	0.4	0.1	0.4	0.8	0.6	0.0	0.4	1.0	0.9	0.7	1.1	-0.2	0.2	0.4	0.7	0.4	0.8
Vitamin and mineral supplements	0.3	0.4	1.1	0.7	0.8	0.8	0.1	-0.5	0.2	0.5	0.8	0.7	0.4	0.9	0.4	0.1	0.3	0.6	0.5	1.1
Pack years adult smoking proportion	0.3	0.5	2.9	0.6	0.2	0.5	-0.1	0.9	0.2	0.8	-0.2	-1.5	0.4	0.1	0.1	-0.2	-0.1	-0.6	0.6	-1.7
Trunk fat percentage	0.3	1.3	15.0	0.7	0.9	0.8	3.9	0.7	-0.1	0.4	-1.0	0.5	-0.4	-0.1	-0.1	0.8	0.6	0.5	0.6	-1.1
Fed-up feelings	0.3	0.5	4.5	-0.3	-0.0	-0.3	0.1	-0.6	2.1	-0.2	-0.6	-0.2	-0.1	-1.3	-0.2	-0.1	-0.4	0.1	-0.7	0.2
Relative age voice broke	0.3	0.5	2.5	0.7	0.6	0.5	-1.6	0.7	-0.4	0.6	0.2	0.4	0.9	0.3	0.4	0.4	0.6	0.8	0.4	0.9
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	2.0	0.0	0.0	0.3	-0.0	0.4	-1.4	-0.1	-0.7	0.0	0.1	0.4	0.2	-1.1	0.3	0.0	0.8	-1.0
Multivitamins +/- minerals	0.3	0.3	2.0	0.3	-0.1	0.1	0.5	1.4	-0.0	0.4	0.5	-0.3	0.8	1.0	0.3	0.7	0.5	0.4	0.3	-0.3
Medication: Atenolol	0.3	0.4	1.0	1.0	-0.0	0.5	0.7	0.7	0.6	0.8	0.4	-0.7	0.6	0.2	0.9	0.3	0.9	0.5	0.7	-0.5
Medication: Levothyroxine sodium	0.3	0.5	2.8	0.5	-0.3	-0.0	-0.8	0.2	1.7	0.4	-0.2	-0.8	-0.5	-0.8	-0.5	1.1	0.6	-0.5	-0.8	-0.4
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	3.1	0.0	-0.2	-0.6	-0.3	0.1	0.3	-0.1	-0.3	-1.8	-0.3	0.5	0.4	-0.7	-0.1	-0.7	-0.4	-1.1
Impedance of arm (right)	0.3	1.2	6.5	0.1	0.6	0.2	-1.9	0.5	0.4	0.1	1.2	2.3	1.3	-0.1	0.5	0.6	0.3	1.2	0.0	2.5
Trunk fat-free mass	0.3	1.7	12.5	-0.2	-0.3	0.4	2.2	-0.5	-3.5	-0.1	-0.9	-1.0	-0.8	1.4	-0.0	-0.8	-0.4	0.3	1.6	-1.8
Alcohol intake versus 10 years previously	0.3	0.4	3.1	-0.2	0.9	-0.2	-1.8	-0.1	0.3	-0.2	-0.4	0.0	-0.5	-1.3	0.4	-0.5	0.1	-0.3	-0.3	0.3
Falls in the last year	0.3	0.4	2.1	0.4	-0.4	0.5	-0.2	0.0	-0.9	0.2	-0.3	-1.4	-0.4	0.2	0.2	-0.9	0.0	-0.3	0.8	-1.4
Asthma	0.3	0.5	1.8	0.8	0.2	0.9	-0.3	0.7	-0.0	0.8	-0.1	0.6	1.2	1.4	0.6	0.6	0.6	0.8	0.6	0.2
Medication: Lansoprazole	0.3	0.3	2.2	0.2	-0.6	0.1	0.6	-0.1	-0.0	0.3	0.2	-1.5	0.3	0.2	0.1	-0.7	-0.0	-0.6	-0.2	-1.1
Illnesses of mother	0.3	0.4	1.6	-0.2	0.1	0.1	1.0	-1.3	-1.0	-0.3	-0.2	-1.1	-0.5	0.2	0.1	0.1	-0.8	-0.3	0.4	-0.4
Trunk predicted mass	0.3	1.7	13.1	-0.2	-0.4	0.4	2.3	-0.5	-3.6	-0.1	-0.8	-0.9	-0.8	1.4	-0.0	-0.8	-0.3	0.3	1.6	-1.8
Medication: Paracetamol	0.3	0.5	3.3	0.8	0.1	0.5	0.7	1.0	1.8	0.9	0.6	-0.6	0.3	-0.5	0.4	-0.5	0.6	0.4	-0.3	0.2
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.4	0.1	-0.3	0.1	-1.3	-0.3	0.8	0.3	0.6	0.7	1.0	0.9	-0.5	-0.2	-0.1	0.6	-0.1	1.6
Medication: Amlodipine	0.3	0.4	2.2	0.0	0.2	0.1	0.8	0.4	-0.9	-0.0	-0.0	-1.2	-0.5	-0.3	-0.1	0.7	0.0	-0.5	0.3	-1.5
Arm fat-free mass (right)	0.3	1.5	9.5	-0.1	0.2	0.4	3.1	-0.3	-2.7	-0.0	-1.0	-0.9	-0.8	0.9	-0.3	-0.2	-0.2	0.2	1.2	-1.8
Number of children fathered	0.3	0.3	1.6	-0.2	0.4	0.2	0.4	-0.5	1.2	0.1	-0.9	-0.6	-0.1	1.1	-0.7	-0.5	-0.5	-0.1	-0.5	0.2
Pulse wave peak to peak time	0.3	0.4	1.7	-0.5	-0.5	-0.7	0.6	-0.4	-0.1	-0.6	0.2	1.3	-0.1	0.2	0.4	0.5	0.0	0.3	-0.5	1.3
Emphysema/chronic bronchitis	0.3	0.4	2.0	0.1	-0.0	-0.1	0.4	1.1	-1.4	-0.0	-0.8	1.2	-0.1	-0.1	-0.4	-0.3	0.9	0.4	0.2	-0.0
Medication: Omeprazole	0.3	0.3	2.1	0.6	0.0	0.6	-0.0	0.1	-0.0	0.6	-0.0	-1.5	0.6	0.6	0.3	-0.1	0.2	0.3	0.8	-0.8
Arm predicted mass (right)	0.3	1.4	8.0	-0.1	0.3	0.4	2.8	-0.1	-2.6	0.0	-1.0	-1.0	-0.8	1.1	-0.3	-0.3	-0.2	0.3	1.2	-1.8
Overall health rating	0.3	0.7	4.2	0.9	0.4	0.6	0.2	1.2	0.7	0.9	-0.3	-1.7	0.4	-0.3	0.0	0.4	0.6	-0.4	0.3	-2.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.7	-0.5	-0.9	-0.6	0.9	0.0	-0.4	-0.5	0.2	0.5	0.3	0.8	-0.4	-1.3	-0.4	-0.0	-0.2	0.3
Supplements: Vitamin C	0.3	0.3	1.5	0.5	-0.6	0.1	0.3	0.8	-0.7	0.3	-0.5	0.0	-0.3	-1.2	0.1	-0.1	0.8	-0.1	0.3	-1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.9	0.3	-0.9	0.4	-0.4	-0.5	-0.9	-0.0	0.1	-0.9	0.0	0.9	0.6	-0.3	-0.0	0.3	0.9	-0.9
Whole body fat-free mass	0.3	2.0	11.2	-0.5	-0.6	0.0	2.7	-0.6	-3.4	-0.4	-1.4	-1.2	-1.2	0.9	-0.3	-1.1	-0.6	-0.1	1.3	-2.3
Long-standing illness, disability or infirmity	0.3	0.5	2.2	0.4	-0.8	0.3	-0.9	0.1	-1.5	0.4	-1.2	-0.3	0.4	0.4	0.7	0.4	0.3	-0.1	0.9	-1.0
Breast cancer (self-reported)	0.3	0.3	0.9	-0.7	-0.5	-0.6	0.9	0.5	0.0	-0.8	-1.0	0.3	-0.4	-0.8	-0.7	0.1	-0.4	-0.3	-0.7	-0.3
Commuting to job workplace: Public transport	0.3	0.4	2.1	-0.6	0.3	-0.4	-1.5	-0.2	-0.2	-0.6	-0.7	-0.8	-0.3	-0.3	-0.2	0.3	-0.5	-1.0	-0.2	-0.4
Ever smoked	0.3	0.5	3.2	-0.3	-0.6	0.0	-0.6	-1.8	-0.8	-0.4	-1.2	-0.6	-0.6	0.0	0.1	0.0	-0.6	-0.1	0.4	-0.7
Arm fat-free mass (left)	0.3	1.7	9.1	-0.2	-0.1	0.4	3.0	-0.5	-2.8	-0.1	-1.3	-1.2	-0.8	1.1	-0.2	-0.4	-0.4	0.1	1.3	-2.1
Myopia	0.3	0.4	2.5	-0.4	1.6	0.2	0.6	-0.1	-1.0	-0.6	0.2	0.6	-0.1	-0.3	0.1	0.7	-0.2	0.3	0.9	0.2
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	1.6	0.1	-1.3	-0.2	-1.2	-0.3	0.3	-0.1	-1.0	0.3	-0.4	-0.5	-0.3	-0.6	0.1	-0.3	-0.5	-0.5
Bipolar Disorder or Schizophrenia	0.2	0.4	1.3	0.1	0.8	0.1	-0.9	0.9	1.1	-0.0	0.3	0.8	0.2	1.0	-0.0	-0.7	0.1	0.1	-0.2	0.7
Depressed Affect (Nagel 2018)	0.2	0.4	1.8	-0.4	-0.9	-0.9	-0.1	-0.5	0.9	-0.5	0.3	-1.4	-0.3	-0.7	-0.4	-0.2	-0.3	-0.6	-0.7	-0.9
Depression (Nagel 2018)	0.2	0.2	1.1	-0.2	-0.1	-0.6	0.8	0.7	1.0	-0.3	0.3	-0.4	0.4	-0.3	-0.1	-0.3	0.0	-0.2	-0.4	-0.7
Neuroticism (Nagel 2018)	0.2	0.4	2.2	0.1	0.2	-0.4	-0.7	0.1	1.1	-0.0	0.9	-1.0	-0.2	-1.5	-0.3	0.6	0.0	-0.4	-0.5	-0.5
Crohns Disease (2017)	0.2	0.5	2.2	0.6	0.9	0.3	-0.8	-0.0	0.6	0.7	0.3	-0.1	0.3	0.4	1.5	1.5	1.1	0.5	-0.2	0.2
Breast Cancer	0.2	0.4	2.9	0.2	-0.7	-0.3	-0.7	0.7	1.7	-0.2	-0.6	-0.0	0.2	0.0	-0.8	0.4	0.5	0.2	-0.8	0.2
Schizophrenia (2014)	0.2	0.4	1.6	-0.1	0.9	0.2	-0.9	0.9	0.7	-0.1	0.6	0.8	0.6	1.2	0.2	-1.0	-0.1	-0.1	0.1	0.2
Systolic Blood Pressure	0.2	0.8	3.1	0.3	0.4	0.5	1.3	1.8	-0.7	0.4	0.9	-0.4	0.6	0.2	1.0	1.0	0.6	0.2	1.1	-1.7
Allergy or Eczema	0.2	0.5	1.5	0.4	-0.1	0.8	-0.9	-0.6	0.6	0.6	0.1	-0.5	1.2	1.1	1.0	-0.3	-0.2	0.3	1.0	0.1
Neuroticism	0.2	0.6	2.5	0.5	0.3	-0.1	-0.4	0.4	1.5	0.4	0.6	-1.6	-0.0	-1.3	0.0	0.6	0.4	-0.2	-0.4	-1.0
Chronotype (morning person)	0.2	0.4	3.8	0.1	-0.4	-0.6	0.6	0.1	1.9	0.3	-0.3	-0.0	-0.0	0.3	-0.1	-0.3	0.1	-0.1	-1.2	-0.2
Hand grip strength (left)	0.2	0.4	1.5	-0.2	-0.5	-0.6	-1.2	-1.1	0.1	-0.3	-0.8	-0.1	-0.2	0.8	-0.2	1.1	0.1	0.4	-0.5	0.9
Average weekly spirits intake	0.2	0.2	0.8	0.4	0.7	0.3	0.3	0.5	0.9	0.5	0.3	-0.2	0.2	-0.0	0.4	0.9	0.4	-0.0	-0.1	-0.3
Relative age of first facial hair	0.2	0.4	4.3	0.3	-0.3	0.3	-2.1	-0.1	-0.5	0.3	0.1	-0.5	0.7	0.8	0.3	-0.3	-0.1	0.1	0.3	0.3
Hand grip strength (right)	0.2	0.7	3.1	-0.0	-0.0	-0.3	-1.3	-0.8	-0.1	-0.0	-1.2	0.6	0.5	1.2	-0.1	1.8	0.3	0.8	-0.0	1.2
Age when periods started (menarche)	0.2	0.5	1.4	1.0	-0.3	0.5	0.1	0.3	0.9	1.0	1.0	0.9	0.5	-0.5	0.6	0.5	1.2	0.4	0.3	0.7
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	1.2	-0.5	0.1	-0.4	0.2	0.0	0.5	-0.4	0.2	1.1	0.1	0.4	0.0	-0.8	-0.5	0.0	-0.8	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	2.2	-0.1	-0.8	-0.5	0.5	0.0	0.2	-0.2	0.3	-0.9	-0.1	-0.1	0.2	-0.8	-0.1	-0.6	-0.0	-1.5
Hearing difficulty/problems with background noise	0.2	0.3	1.2	0.0	0.3	-0.0	0.9	0.1	-0.6	0.1	-0.4	1.1	0.1	-0.8	-0.0	0.6	0.5	0.7	0.4	0.4
Medication: Ramipril	0.2	0.3	1.3	-0.1	-0.1	-0.4	-0.4	0.9	-0.1	-0.5	-0.4	1.1	-0.3	-1.1	-0.6	-0.2	0.4	0.3	-0.3	0.1
Medication: Simvastatin	0.2	0.3	2.2	0.3	-0.0	-0.0	1.5	0.9	-0.0	-0.1	-0.7	0.9	-0.5	-0.6	0.1	0.2	0.6	0.3	-0.3	-0.3
Medication: Cholesterol lowering	0.2	0.3	1.7	0.3	0.0	0.2	1.3	0.2	-0.1	0.1	0.2	-0.6	-0.6	-0.4	0.6	0.9	0.3	-0.3	0.1	-1.2
Glaucoma (self-reported)	0.2	0.2	2.1	0.5	0.6	0.5	-1.4	0.2	0.2	0.5	-0.2	0.3	-0.2	-0.0	0.4	-0.3	0.2	-0.2	0.1	0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	2.7	0.3	-0.1	-0.0	-1.2	-0.4	1.6	0.3	-0.2	-0.0	-0.4	-0.7	-0.3	1.2	0.3	-0.2	-0.7	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.3	0.2	0.1	-0.2	-0.8	-0.0	1.2	0.1	-0.8	-0.8	-0.1	0.3	0.5	-0.4	0.1	-0.2	-0.6	-0.5
Eye problems/disorders: None of the above	0.2	0.2	1.0	0.2	-0.6	-0.1	0.8	-0.1	1.0	-0.0	0.3	0.7	0.3	0.1	0.4	0.2	0.2	0.6	-0.1	0.6
Mouth/teeth dental problems: Loose teeth	0.2	0.3	1.1	0.5	-0.6	0.3	0.3	0.6	0.8	0.5	-0.5	-0.6	0.4	-0.7	0.1	0.3	0.5	-0.2	-0.1	-1.0
Medication: Allopurinol	0.2	0.3	1.3	-0.5	0.1	-0.7	-0.8	-0.1	-0.0	-0.7	0.3	0.9	-1.1	-0.2	-0.7	-0.3	0.2	-0.2	-0.8	0.1
Alcohol intake frequency.	0.2	0.5	1.9	0.6	1.4	0.5	-0.5	0.5	1.4	0.7	-0.8	-0.8	0.4	-1.0	-0.2	0.9	0.3	-0.0	-0.3	0.0
Comparative height size at age 10	0.2	1.1	3.5	-1.6	0.6	-0.9	0.8	-0.9	-1.2	-1.3	0.3	-1.0	-1.1	0.7	-0.9	-1.1	-1.9	-0.9	-0.3	-0.8
Family relationship satisfaction	0.2	0.3	1.0	-0.1	0.9	0.2	-0.5	-0.6	-0.2	0.0	0.6	0.8	-0.3	0.7	-0.0	0.4	-0.1	0.1	0.1	1.0
Handedness (chirality/laterality): Left-handed	0.2	0.3	2.0	-0.6	-0.5	-0.4	-0.1	-1.4	-0.8	-0.4	0.2	0.1	0.0	0.2	0.2	-0.2	-0.8	-0.0	0.1	0.2
Mood swings	0.2	0.4	2.4	-0.2	-0.1	-0.3	-0.9	-0.5	1.1	-0.2	0.2	-1.5	-0.4	-0.1	-0.8	-0.2	-0.4	-0.6	-0.5	-0.9
Ever taken oral contraceptive pill	0.2	0.2	2.0	0.1	-0.2	-0.1	-1.4	-0.4	0.6	-0.1	-0.1	0.5	-0.1	0.1	0.1	0.9	0.3	0.1	-0.4	0.3
Alcohol drinker status: Never	0.2	0.2	0.8	0.0	0.3	0.0	-0.3	-0.5	0.8	0.1	-0.1	0.1	0.0	0.4	-0.6	-0.5	-0.2	0.1	-0.8	0.9
Supplements: Calcium	0.2	0.2	0.8	-0.5	0.1	-0.1	-0.9	-0.5	-0.6	-0.2	0.3	-0.2	-0.1	0.8	-0.7	-0.6	-0.7	-0.6	0.0	-0.2
Schizophrenia vs Biploar Disorder	0.1	0.1	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	-0.4	-0.2	-0.8	-0.6	0.3	-0.1
Verbal and Numeric Reasoning (VNR)	0.1	0.4	1.9	-0.4	-0.7	-0.7	-0.3	0.5	0.4	-0.7	-0.1	1.4	0.2	0.6	-0.3	0.3	0.3	0.4	-0.7	0.8
LDL Cholesterol	0.1	0.2	2.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.5	-0.1	0.2	-0.4	-0.7	-0.4	-1.6
Neuroticism (2016)	0.1	0.2	0.6	0.5	0.1	0.5	0.8	0.1	0.4	0.5	0.3	-0.2	0.4	-0.1	0.1	0.4	0.2	0.8	0.3	0.3
Blood Eosinophil Count	0.1	0.8	4.4	0.4	-0.8	0.4	-0.8	-0.4	-0.2	0.6	2.1	-1.0	1.0	1.7	0.2	-0.6	-0.5	0.1	1.0	-0.3
Blood White Count	0.1	0.4	2.7	0.9	-1.6	-0.1	-0.6	0.8	0.7	0.6	0.0	0.1	0.5	0.5	-0.1	-0.1	1.0	0.2	-0.2	-0.5
Height	0.1	2.1	15.6	-0.8	1.6	0.3	2.3	-0.1	-4.0	-0.4	2.2	-0.3	-0.3	1.5	-0.1	0.4	-0.8	1.2	1.7	-0.1
Hair Pigment	0.1	2.0	12.0	1.7	0.6	1.5	3.5	1.4	-1.1	1.8	1.4	-1.1	0.8	0.2	0.1	0.5	1.3	1.0	1.4	-1.2
Tanning	0.1	1.1	5.8	-1.0	-1.2	-0.9	-1.7	-0.7	-0.8	-1.1	0.1	-0.8	-0.7	1.0	0.3	-2.4	-1.0	-1.0	0.2	-0.9
Sitting height	0.1	1.0	9.7	-1.1	0.0	-0.5	-0.4	-0.1	-3.1	-0.9	0.3	-1.0	-0.5	0.1	-0.7	-0.7	-1.0	0.1	0.7	-0.5
Hair/balding pattern: Pattern 2	0.1	0.1	0.4	0.2	-0.4	-0.4	0.3	0.5	0.1	0.0	0.5	-0.3	0.4	0.6	0.4	-0.3	0.5	0.2	-0.1	-0.6
Forced vital capacity (FVC)	0.1	0.5	2.9	0.2	0.8	0.1	0.7	-0.2	-0.7	0.3	1.0	0.6	0.4	-0.6	0.4	0.3	0.1	1.1	0.1	1.7
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	1.1	0.3	0.3	0.0	-0.2	-0.0	1.0	0.3	0.1	0.0	0.2	-0.0	0.6	0.1	0.7	0.2	-0.3	0.1
Hair/balding pattern: Pattern 3	0.1	0.1	0.4	-0.1	-0.3	-0.1	-0.4	-0.4	-0.5	-0.4	-0.1	-0.2	-0.6	0.1	-0.7	0.4	-0.2	-0.4	0.3	-0.6
Standing height	0.1	1.4	14.7	-0.9	0.9	-0.0	0.6	0.2	-3.8	-0.7	0.6	1.1	-0.3	1.2	-0.3	-0.6	-0.5	1.1	1.1	1.0
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.6	0.5	-0.2	0.0	0.4	0.4	0.7	0.5	-0.1	-0.3	0.2	0.0	0.1	-0.6	0.3	-0.1	-0.4	-0.5
Forced vital capacity (FVC), Best measure	0.1	0.4	1.8	0.4	0.7	0.4	0.7	-0.2	-0.9	0.5	0.5	0.0	0.8	0.3	0.7	0.2	0.1	1.2	0.5	1.3
Number of full sisters	0.1	0.2	0.5	-0.7	-0.2	-0.7	-0.6	0.3	0.5	-0.7	0.0	0.1	0.0	-0.3	-0.3	-0.6	-0.2	-0.5	-0.4	-0.2
Ever had bowel cancer screening	0.1	0.2	0.9	-0.0	-0.0	-0.2	-0.9	-0.1	-0.8	-0.1	-0.4	0.5	-0.1	-0.3	-0.3	-0.2	0.2	0.4	0.0	0.6
Medication: Bendroflumethiazide	0.1	0.2	0.9	0.3	-0.1	0.1	0.8	0.6	-0.4	0.2	0.1	1.0	0.1	0.4	0.3	-0.0	0.5	0.3	-0.1	0.2
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

ITFG3

Models

Trait associations