TWAS hub - JAG2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Pancreas	0.188	0.070	0.0016	0.219	NA	0.166	NA	0.186	1.2e-09	NA	1.6e-07	NA	2.6e-08
2	TCGA	Glioblastoma Multiforme	0.139	0.068	0.0054	-0.009	0.017	-0.009	NA	-0.009	7.4e-01	0.097	7.9e-01	NA	8.4e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood clot in the leg (DVT)	8.1	10.5	20.3	-4.5	-0.8
Deep venous thrombosis (DVT) (self-reported)	7.2	9.3	18.2	-4.3	-0.6
Ever highly irritable/argumentative for 2 days	5.7	6.9	13.7	-3.7	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	4.2	4.9	9.0	-3.0	-0.8
Family relationship satisfaction	3.9	4.8	7.8	1.3	2.8
Blood White Count	3.8	28.4	55.6	-7.5	1.1
Breast Cancer	3.1	7.4	12.7	-3.6	-1.4
Blood Platelet Count	3.0	34.4	43.2	-5.1	6.6
Bilateral oophorectomy (both ovaries removed)	2.8	3.2	5.4	2.3	1.0
Back pain experienced in last month	2.8	4.0	8.1	2.8	-0.2
Medication: Lisinopril	2.8	3.7	6.0	2.4	1.2
Loneliness, isolation	2.7	3.7	7.2	0.4	2.7
Ovarian Cancer	2.6	3.4	6.8	2.6	-0.2
Eye problems/disorders: Cataract	2.5	2.9	4.6	2.1	1.1
Irritable Bowel Disease (IBD)	2.1	5.0	6.1	2.0	2.5
Body Mass Index (BMI) (2010)	2.1	2.8	5.7	0.0	-2.4
Medication: Atorvastatin	2.0	2.5	5.0	-0.3	-2.2
Chronotype (morning person)	1.9	4.4	5.9	-1.7	-2.4
Medication for cholesterol, blood pressure or diabetes	1.9	3.1	5.2	2.3	1.0
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	5.7	-2.4	0.3
Medication: Omeprazole	1.8	2.1	3.8	-1.9	-0.7
Number of full brothers	1.7	2.2	4.3	0.0	-2.1
Primary Biliary Cirrhosis	1.6	2.2	3.0	1.7	-1.2
Past tobacco smoking	1.6	2.9	5.7	-2.4	0.2
Commuting to job workplace: Walk	1.5	1.6	2.3	-0.9	-1.5
Wears glasses or contact lenses	1.5	1.8	3.4	1.9	-0.4
Fractured/broken bones in last 5 years	1.5	1.9	3.7	-0.4	-1.9
Schizophrenia (2018)	1.4	2.9	5.2	2.3	0.7
Multivitamins +/- minerals	1.4	1.8	3.5	0.2	1.9
Waist circumference	1.4	5.1	9.9	-3.2	0.5
Time employed in main current job	1.4	1.6	2.8	1.7	-0.7
Mouth/teeth dental problems: Dentures	1.4	2.3	2.8	1.3	-1.7
Mouth/teeth dental problems: Bleeding gums	1.4	1.9	2.0	1.4	1.3
Heart disease (mother)	1.4	1.8	3.4	0.4	1.8
Smoking status: Previous	1.4	2.1	4.2	2.0	-0.3
Heart disease (siblings)	1.4	1.7	3.0	1.7	-0.6
Crohns Disease (2017)	1.3	2.8	3.4	1.9	1.5
Verbal and Numeric Reasoning (VNR)	1.3	3.2	4.5	-2.1	1.4
HDL Cholesterol	1.3	2.2	4.4	0.0	-2.1
Pack years adult smoking proportion	1.3	2.0	2.6	-1.6	1.2
Townsend deprivation index at recruitment	1.3	1.8	3.2	1.8	0.6
Medication: Cholesterol lowering	1.3	2.1	3.3	-1.8	-0.9
Exposure to tobacco smoke outside home	1.3	1.7	2.5	-1.6	-1.0
Age started oral contraceptive pill	1.3	1.6	2.1	1.5	1.1
Depression (Nagel 2018)	1.2	1.8	1.8	-1.3	1.4
Ulcerative Colitis (UC)	1.2	2.3	4.2	0.7	2.1
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	2.4	-1.5	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	2.4	-1.5	0.9
Qualifications: CSEs or equivalent	1.2	1.6	1.9	-1.1	-1.4
Financial difficulties in last 2 years	1.2	1.6	2.6	1.6	-0.8
Medication: Amlodipine	1.2	1.7	2.8	0.7	-1.7
Worry too long after embarrassment	1.2	2.0	2.1	1.4	1.4
Number of children fathered	1.2	1.4	2.0	1.4	0.9
Mean time to correctly identify matches	1.2	2.4	4.7	-2.2	0.1
Chest pain or discomfort	1.2	1.8	3.1	0.7	1.8
Guilty feelings	1.2	1.8	2.4	1.6	1.1
Average weekly beer plus cider intake	1.2	1.7	1.8	1.3	-1.3
Medication: Omeprazole (e.g. Zanprol)	1.2	1.5	2.2	-1.5	-0.9
Pack years of smoking	1.2	1.8	2.4	-1.5	1.1
Blood Eosinophil Count	1.1	8.4	16.3	-4.0	0.7
Sensitivity / hurt feelings	1.1	1.9	2.2	1.5	1.2
Systolic blood pressure, automated reading	1.1	3.1	6.3	-2.5	-0.0
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	2.2	-1.5	0.8
Hair/balding pattern: Pattern 3	1.1	1.6	2.4	-0.9	-1.6
Loud music exposure frequency	1.1	1.2	1.7	0.8	-1.3
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	2.4	-0.5	1.6
Friendships satisfaction	1.1	1.4	2.8	0.2	1.7
Reaction Time	1.0	1.8	3.6	-1.9	-0.1
Neuroticism (2016)	1.0	1.4	1.6	-1.3	1.1
Ulcerative Colitis	1.0	1.4	2.9	0.0	1.7
Hypothyroidism (self reported)	1.0	2.4	4.6	-0.4	-2.1
Lung FVC	1.0	4.9	9.7	3.1	0.0
Average weekly spirits intake	1.0	1.3	2.4	1.6	-0.4
Stomach or abdominal pain in last month	1.0	1.3	2.5	0.1	1.6
Hip circumference	1.0	4.2	8.4	-2.9	0.0
Lung cancer (father)	1.0	1.2	2.2	-0.5	1.5
High blood pressure (siblings)	1.0	1.5	1.8	1.1	1.3
Tinnitus: Yes, now most or all of the time	1.0	1.2	1.5	1.2	0.9
Eye problems/disorders: Glaucoma	1.0	1.2	1.7	-1.3	0.9
Alcohol drinker status: Never	1.0	1.3	2.5	-0.2	1.6
Diastolic blood pressure, automated reading	1.0	3.2	4.4	-2.1	-1.4
Alzheimer’s Disease (in mother)	0.9	1.1	1.1	1.0	1.0
Systolic Blood Pressure	0.9	4.3	7.7	-2.8	-0.9
Smoking Status	0.9	2.2	4.4	2.1	-0.1
Hair/balding pattern: Pattern 2	0.9	1.2	1.3	1.0	1.1
Pulse wave Arterial Stiffness index	0.9	1.1	2.1	-1.5	0.0
Hair/balding pattern: Pattern 4	0.9	2.1	4.1	2.0	-0.2
Headache pain in last month	0.9	1.5	1.8	1.1	1.3
Health satisfaction	0.9	1.1	2.3	-1.5	0.1
Qualifications: College or University degree	0.9	2.8	5.0	0.8	2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	2.0	1.4	-0.2
Leg fat percentage (left)	0.9	3.3	6.3	-2.5	-0.5
Irritability	0.9	1.6	2.9	-1.7	0.5
Bipolar Disorder (2018)	0.8	1.3	1.5	-1.2	1.1
Intelligence (Savage-Jansen 2018)	0.8	2.4	2.4	-1.6	1.6
Schizophrenia (2014)	0.8	1.7	3.1	1.8	0.5
Medication for hormone replacement therapy	0.8	0.9	0.9	0.9	-0.9
Number of incorrect matches in round	0.8	1.3	1.4	1.2	-1.1
Pain all over the body in last month	0.8	0.9	1.6	-0.4	1.3
Fluid intelligence score	0.8	1.6	2.6	-1.6	0.7
Breastfed as a baby	0.8	1.0	1.9	-1.4	0.0
Leg fat percentage (right)	0.8	3.0	5.7	-2.4	-0.6
Pulse wave peak to peak time	0.8	0.9	1.8	1.4	0.1
Medication: Blood pressure	0.8	1.5	1.9	-1.4	-1.0
Depressed Affect (Nagel 2018)	0.7	1.4	1.8	-1.0	1.4
Alzheimer’s Disease (in father)	0.7	0.8	1.0	-1.0	-0.7
Respiratory disease	0.7	1.6	2.0	1.1	-1.4
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.0	-0.0	1.4
Medication: Ramipril	0.7	0.9	1.6	-1.3	-0.3
Worrier / anxious feelings	0.7	1.3	2.5	1.6	0.3
Happiness	0.7	0.8	1.6	-0.3	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	1.6	-1.3	-0.5
Supplements: Vitamin C	0.7	0.8	1.4	-0.3	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	2.5	-1.6	-0.7
Arm fat percentage (left)	0.7	2.9	5.6	-2.4	-0.4
Medication: Aspirin	0.7	0.9	1.9	-1.4	0.0
Ever smoked	0.7	1.2	2.4	1.5	0.3
Bipolar Disorder or Schizophrenia	0.6	1.5	1.7	1.1	1.3
Prostate Cancer	0.6	0.8	1.1	-1.0	-0.8
Lung FEV1/FVC ratio	0.6	3.0	5.8	-0.3	2.4
Tanning	0.6	6.9	12.6	-1.1	-3.5
Hearing difficulty/problems: Yes	0.6	0.9	1.4	1.2	-0.7
Medication: Co-codamol	0.6	0.7	1.2	-0.4	-1.1
Medication: Metformin	0.6	0.8	1.6	-0.2	-1.3
Diverticular disease/diverticulitis (self-reported)	0.6	0.8	1.3	1.1	-0.5
Medication: Levothyroxine sodium	0.6	1.1	1.8	1.3	0.6
Trunk fat mass	0.6	2.5	4.9	-2.2	-0.2
Weight	0.6	2.9	5.9	-2.4	-0.0
Arm fat percentage (right)	0.6	2.2	4.2	-2.1	-0.5
Falls in the last year	0.6	0.8	1.7	-1.3	-0.0
Medication: Lansoprazole	0.6	0.7	1.3	-1.2	0.3
Glaucoma (self-reported)	0.6	0.7	1.3	-1.1	-0.3
Body fat percentage	0.6	2.4	4.7	-2.2	-0.2
Leg fat mass (right)	0.6	2.3	4.2	-2.0	-0.6
Number of full sisters	0.6	0.7	1.3	1.1	0.2
Medication: Aspirin	0.6	0.9	1.7	-1.3	-0.1
Knee pain experienced in last month	0.6	1.0	1.8	0.4	-1.4
Breast cancer (self-reported)	0.6	0.7	0.8	0.8	0.9
Ever taken oral contraceptive pill	0.6	0.6	0.9	0.7	0.9
Leg fat mass (left)	0.6	2.4	4.8	-2.2	-0.3
Lupus	0.5	0.8	1.3	0.6	-1.1
Blood Red Count	0.5	5.3	9.8	-3.1	-0.9
Waist Hip Ratio (WHR)	0.5	2.2	3.6	-0.9	1.9
Vitamin and mineral supplements	0.5	0.6	1.3	0.0	-1.1
Supplements: Zinc	0.5	0.5	1.1	-1.0	0.0
Relative age voice broke	0.5	0.7	1.1	-1.1	-0.6
High blood pressure (mother)	0.5	0.8	0.8	0.8	-0.9
Body mass index (BMI)	0.5	2.2	4.1	-2.0	-0.6
Alcohol usually taken with meals	0.5	0.7	1.4	1.2	0.3
Nervous feelings	0.5	0.9	1.7	-1.3	0.0
Illnesses of siblings	0.5	0.6	1.0	-1.0	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	0.8	-0.5	-0.9
Illnesses of mother	0.5	0.7	1.1	-0.5	-1.1
Arm fat mass (right)	0.5	2.2	4.3	-2.1	-0.1
Exposure to tobacco smoke at home	0.5	0.6	0.8	-0.9	-0.6
Gout (self-reported)	0.5	0.7	0.7	-0.8	-0.8
Birth weight	0.5	1.2	2.3	-0.1	-1.5
Forced vital capacity (FVC), Best measure	0.5	1.6	2.2	1.5	1.1
Medication for pain relief, constipation, heartburn	0.5	0.9	1.7	1.3	-0.1
Whole body fat mass	0.5	2.2	4.5	-2.1	-0.1
Hypertension (Self-reported)	0.5	1.3	1.8	-1.3	-0.9
Handedness (chirality/laterality): Left-handed	0.5	0.7	1.3	-1.1	0.2
Osteoporosis (self-reported)	0.5	0.6	0.6	0.7	-0.8
Arm fat mass (left)	0.5	2.2	4.3	-2.1	-0.2
Medication: Blood pressure	0.5	0.9	1.2	0.7	-1.1
Medication: Bendroflumethiazide	0.5	0.7	0.9	-0.9	-0.7
Ever had prostate specific antigen (PSA) test	0.5	0.6	0.7	0.9	0.7
Unable to work because of sickness or disability	0.5	0.6	1.3	1.1	0.0
Myopia	0.5	0.7	1.0	1.0	0.7
Neuroticism (Nagel 2018)	0.4	1.0	1.0	-1.0	1.0
Mean Putamen Volume	0.4	0.5	0.5	0.7	0.7
Rheumatoid Arthritis	0.4	0.6	1.1	1.0	-0.4
BMI	0.4	2.3	4.6	-2.2	0.0
Allergy or Eczema	0.4	1.1	2.2	1.5	0.1
Trunk fat percentage	0.4	1.8	3.5	-1.9	-0.0
Fed-up feelings	0.4	0.8	1.2	-0.6	1.1
Age when periods started (menarche)	0.4	1.0	1.9	-1.4	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	1.8	-1.4	0.4
Chronic bronchitis/emphysema (father)	0.4	0.4	0.9	-0.0	-0.9
Qualifications: None of the above	0.4	0.8	1.5	1.2	-0.4
Depression (self-reported)	0.4	0.5	0.6	0.7	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	1.5	1.2	1.1
Birth weight of first child	0.4	0.8	1.4	0.3	-1.2
Pulse wave reflection index	0.4	0.5	0.5	-0.7	-0.6
Eye problems/disorders: None of the above	0.4	0.5	0.9	0.3	-1.0
Angina (self-reported)	0.4	0.6	0.9	1.0	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.1	-0.6	-1.0
Medication for cholesterol	0.4	0.6	1.0	-0.4	1.0
Mineral and other dietary supplements	0.4	0.5	1.0	-1.0	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	1.4	1.2	0.6
Number of self-reported non-cancer illnesses	0.4	0.8	1.3	-1.1	-0.5
Average weekly champagne plus white wine intake	0.4	0.5	0.7	0.6	-0.8
Risk taking	0.4	0.6	1.1	1.0	0.2
Alcohol drinker status: Previous	0.4	0.4	0.8	0.9	-0.3
Worry (Nagel 2018)	0.3	0.6	0.7	-0.8	-0.8
Crohns Disease (2012)	0.3	0.5	1.0	0.0	1.0
Triglycerides	0.3	0.4	0.9	0.0	0.9
Ever used hormone-replacement therapy (HRT)	0.3	0.4	0.6	0.7	-0.4
Angina	0.3	0.4	0.6	0.7	-0.5
Diabetes (mother)	0.3	0.4	0.8	-0.9	0.1
Severe depression (siblings)	0.3	0.3	0.6	0.8	-0.3
High blood pressure	0.3	0.8	0.8	-0.9	-0.8
Forced vital capacity (FVC)	0.3	1.3	2.6	1.6	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	1.6	-1.2	0.0
Mouth/teeth dental problems	0.3	0.5	0.6	-0.6	0.8
Neuroticism score	0.3	0.6	1.2	0.3	1.1
Father’s age at death	0.3	0.4	0.8	0.9	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.8	-0.3	0.9
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	1.1	1.0	0.9
Pulse rate	0.3	0.5	0.9	-0.3	0.9
Length of working week for main job	0.3	0.4	0.4	0.6	-0.6
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.5	0.5	0.7
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.4	-0.6	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.5	-0.7	0.4
Migraine (self-reported)	0.3	0.4	0.4	0.6	-0.6
Alcohol intake frequency.	0.3	0.6	0.8	-0.9	0.7
Average weekly red wine intake	0.3	0.5	0.7	0.9	0.5
Long-standing illness, disability or infirmity	0.3	0.5	0.5	-0.6	0.7
Asthma (self-reported)	0.3	0.6	0.6	0.8	-0.8
Illnesses of father: None of the above (group 1)	0.3	0.3	0.6	-0.3	0.8
Miserableness	0.3	0.6	0.6	-0.8	0.8
Pain type(s) experienced in last month: Hip pain	0.3	0.3	0.6	0.8	0.1
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.8	-0.1	0.9
Number of operations (self-reported)	0.3	0.5	0.9	-0.2	0.9
Commuting to job workplace: Cycle	0.3	0.3	0.4	0.5	-0.6
Cholesterol lowering medication	0.3	0.4	0.7	0.8	-0.5
Supplements: Calcium	0.3	0.4	0.5	0.5	0.7
Basal cell carcinoma (self-reported)	0.3	0.3	0.5	-0.7	-0.3
HbA1C	0.2	0.3	0.5	-0.1	0.7
Heel T-Score	0.2	1.7	3.4	-1.8	0.1
Cardiovascular Disease	0.2	0.6	1.0	-0.5	-1.0
Neuroticism	0.2	0.5	0.6	-0.5	0.8
Hand grip strength (left)	0.2	0.5	0.5	0.7	-0.7
Diabetes (father)	0.2	0.2	0.5	0.0	0.7
Leg fat-free mass (left)	0.2	1.0	1.9	-1.4	-0.1
Hand grip strength (right)	0.2	0.7	1.2	0.3	-1.1
Average weekly fortified wine intake	0.2	0.2	0.3	0.4	0.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.3	0.5	-0.2	0.7
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.8	0.9	0.2
Supplements: Glucosamine	0.2	0.3	0.4	0.6	0.5
Leg predicted mass (left)	0.2	0.9	1.9	-1.4	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.4	-0.7	-0.3
Hearing difficulty/problems with background noise	0.2	0.4	0.6	0.8	0.3
Had menopause	0.2	0.2	0.3	-0.3	0.5
Medication: Simvastatin	0.2	0.3	0.4	-0.5	-0.6
Impedance of arm (right)	0.2	0.9	1.4	1.2	0.6
Trunk fat-free mass	0.2	1.0	1.9	-1.4	-0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.5	0.6	0.7	0.8
Trunk predicted mass	0.2	1.0	1.9	-1.4	-0.3
Tense / ‘highly strung’	0.2	0.3	0.4	-0.7	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.7	0.2	-0.9
Arm fat-free mass (right)	0.2	1.0	1.9	-1.4	-0.1
Shortness of breath walking on level ground	0.2	0.3	0.6	-0.8	-0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.3	0.3	-0.5
Emphysema/chronic bronchitis	0.2	0.2	0.2	-0.5	0.4
Neck or shoulder pain in last month	0.2	0.3	0.5	0.7	-0.3
Arm predicted mass (right)	0.2	0.8	1.7	-1.3	-0.2
Pulse rate, automated reading	0.2	0.6	0.7	-0.8	-0.7
Comparative height size at age 10	0.2	1.1	2.1	1.5	0.0
Suffer from ‘nerves’	0.2	0.4	0.7	-0.8	-0.2
Age at last live birth	0.2	0.3	0.4	-0.7	-0.4
Leg pain on walking	0.2	0.2	0.4	0.6	-0.1
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.2	0.4	0.5
Illnesses of father: Heart disease	0.2	0.3	0.4	0.6	-0.4
Whole body fat-free mass	0.2	0.9	1.8	-1.3	-0.3
Leg fat-free mass (right)	0.2	1.2	2.3	-1.5	0.2
Qualifications: nursing, teaching	0.2	0.3	0.5	-0.3	0.7
Whole body water mass	0.2	1.0	1.9	-1.4	-0.2
Leg predicted mass (right)	0.2	1.3	2.6	-1.6	0.1
Hearing aid user	0.2	0.2	0.3	-0.1	-0.6
Commuting to job workplace: Public transport	0.2	0.3	0.4	0.6	-0.4
High cholesterol (Self-reported)	0.2	0.4	0.5	-0.7	-0.6
Basal metabolic rate	0.2	1.3	2.5	-1.6	-0.2
Arm fat-free mass (left)	0.2	1.2	2.4	-1.5	-0.2
Pain experienced in last month	0.2	0.3	0.5	-0.7	0.2
Alzheimer’s Disease (including proxy)	0.1	0.2	0.3	-0.6	0.2
Fasting Glucose	0.1	0.2	0.3	-0.5	0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.3	0.0	-0.6
Hair Pigment	0.1	3.6	4.3	2.1	-1.7
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.3	-0.5	0.3
Impedance of leg (right)	0.1	0.7	1.4	1.2	0.3
Current tobacco smoking	0.1	0.2	0.4	-0.0	0.6
Taking other prescription medications	0.1	0.1	0.1	0.3	-0.3
Serious illness, injury or assault to yourself	0.1	0.2	0.2	0.2	0.5
Medication: Atenolol	0.1	0.1	0.2	-0.3	-0.4
Sitting height	0.1	0.4	0.6	-0.5	0.8
Impedance of leg (left)	0.1	0.4	0.6	0.8	0.4
Had other major operations	0.1	0.2	0.2	-0.3	0.4
Heart attack	0.1	0.2	0.3	-0.1	-0.6
Diabetes (self-reported)	0.1	0.2	0.4	0.6	-0.1
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.3	-0.1	0.5
Asthma	0.1	0.2	0.4	0.6	-0.2
Impedance of arm (left)	0.1	0.5	0.6	0.8	0.6
Standing height	0.1	0.9	0.9	-1.0	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.2	-0.3	-0.4
Medication: Paracetamol	0.1	0.2	0.2	0.4	0.4
Comparative body size at age 10	0.1	0.3	0.5	-0.5	-0.7
Wheeze or whistling in the chest in last year	0.1	0.2	0.2	-0.4	0.5
Age at first live birth	0.1	0.2	0.4	0.3	0.6
Medication: Seretide 50 evohaler	0.1	0.1	0.3	-0.0	-0.5
Illnesses of siblings: Diabetes	0.1	0.1	0.2	-0.3	0.4
Mood swings	0.1	0.2	0.3	0.2	0.6
Ever had bowel cancer screening	0.1	0.1	0.2	0.3	0.4
Diabetes diagnosed by doctor	0.1	0.2	0.4	-0.1	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.1	-0.1	0.3
Osteoarthritis (self-reported)	0.1	0.2	0.3	0.1	-0.6
Mother’s age at death	0.1	0.1	0.3	0.1	0.5
Financial situation satisfaction	0.1	0.1	0.1	-0.3	-0.3
Illnesses of father: High blood pressure	0.1	0.1	0.2	0.4	-0.0
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.2	0.5	0.4
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.3	-0.0	-0.5
Impedance of whole body	0.1	0.4	0.6	0.8	0.5
Arm predicted mass (left)	0.1	0.7	1.3	-1.2	-0.2
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.0	0.1	0.1	-0.1	-0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.2
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0
Height	0.0	0.2	0.3	0.4	0.5
Number of treatments/medications taken	0.0	0.0	0.0	0.1	-0.1
Relative age of first facial hair	0.0	0.0	0.0	0.1	-0.2
Ever had hysterectomy (womb removed)	0.0	0.1	0.1	-0.0	0.3
Maternal smoking around birth	0.0	0.0	0.0	0.0	-0.2
Allergy	0.0	0.1	0.1	0.1	0.4
Alcohol intake versus 10 years previously	0.0	0.1	0.1	0.3	0.2
Number of live births	0.0	0.0	0.1	0.3	0.1
Noisy workplace	0.0	0.1	0.1	-0.2	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.0	-0.2	-0.2
Prospective memory result	0.0	0.0	0.0	-0.1	-0.1
Peak expiratory flow (PEF)	0.0	0.1	0.1	-0.3	0.3
Medication: Ibuprofen	0.0	0.0	0.0	0.0	0.1
Medication: Allopurinol	0.0	0.0	0.1	0.3	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.1	-0.2	-0.2
Overall health rating	0.0	0.1	0.2	0.1	-0.4
Had major operations	0.0	0.0	0.0	0.1	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	0.1	-0.1
Medication: Gliclazide	0.0	0.0	0.0	0.1	0.1
Smoking status: Current	0.0	0.0	0.1	0.3	0.2
Medication: Paracetamol	0.0	0.0	0.0	0.2	0.2
Ever depressed for a whole week	0.0	0.0	0.1	0.3	0.1

Hub : Genes

JAG2

Models

Trait associations