Hub : Genes

KALRN

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Mucosa	0.2950	0.0630	1.3e-06	0.186	NA	0.214	NA	0.222	1.7e-12	NA	2.4e-14	NA	7.3e-15
2	GTEx	Muscle Skeletal	0.1003	0.0333	8.8e-04	0.084	NA	0.062	NA	0.058	1.2e-08	NA	9.9e-07	NA	2.3e-06
3	GTEx	Pancreas	0.2220	0.0610	2.2e-04	0.099	NA	0.101	NA	0.107	5.9e-05	NA	4.7e-05	NA	2.9e-05
4	GTEx	Thyroid	0.3090	0.0590	1.1e-06	0.161	NA	0.221	NA	0.172	2.5e-12	NA	7.4e-17	NA	3.8e-13
5	TCGA	Colon Adenocarcinoma	0.1120	0.0510	7.2e-03	0.033	0.014	0.012	NA	0.020	5.4e-03	5.1e-02	6.7e-02	NA	2.5e-02
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0871	0.0309	6.5e-05	-0.002	0.024	0.014	NA	0.000	5.9e-01	8.1e-04	8.3e-03	NA	3.3e-01
7	TCGA	Prostate Adenocarcinoma	0.1524	0.0441	1.2e-05	0.052	0.071	0.069	NA	0.083	3.5e-06	6.2e-08	1.1e-07	NA	4.7e-09
8	TCGA	Stomach Adenocarcinoma	0.1190	0.0490	1.1e-03	0.032	0.067	0.037	NA	0.045	2.1e-03	1.5e-05	1.1e-03	NA	3.3e-04
9	TCGA	Thyroid Carcinoma	0.4720	0.0640	2.2e-16	0.186	0.194	0.207	NA	0.224	7.2e-18	1.3e-18	7.6e-20	NA	1.5e-21

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.3	0.5	1.9	-0.0	-0.3	-1.4	-0.6	0.0	-0.1	-0.7	0.2	-1.3
Bipolar Disorder or Schizophrenia	0.6	1.6	6.2	-0.1	-1.2	0.1	-0.5	0.7	-2.5	-1.1	2.2	0.2
Depressed Affect (Nagel 2018)	0.3	0.7	1.8	0.5	-1.1	0.4	1.1	0.1	-0.2	-0.8	-1.3	0.8
Depression (Nagel 2018)	0.5	0.7	2.5	0.2	-0.3	0.4	1.6	-0.0	0.4	-0.3	-1.0	1.5
Intelligence (Savage-Jansen 2018)	1.2	3.8	11.3	1.9	3.0	0.2	-0.3	-3.4	2.1	0.0	-2.2	-1.1
Neuroticism (Nagel 2018)	0.3	0.8	2.1	0.7	-0.6	1.0	0.9	0.3	0.6	-1.2	-1.4	0.8
Schizophrenia (2018)	1.2	2.6	9.6	-0.2	-1.3	1.3	-0.2	0.9	-3.1	-0.8	2.6	1.4
Schizophrenia vs Biploar Disorder	0.5	0.6	1.4	-1.0	-1.2	0.1	-0.2	0.9	-1.2	0.3	0.6	0.6
Worry (Nagel 2018)	0.3	0.7	2.4	0.0	-1.3	-0.6	-0.1	1.5	0.8	-1.2	0.2	-0.0
Alzheimer’s Disease (in mother)	1.0	1.1	2.5	-1.1	0.5	-1.1	-1.5	-0.6	1.6	0.1	-1.0	-1.1
Alzheimer’s Disease (in father)	0.7	0.8	2.6	0.3	0.7	-1.4	-0.4	0.3	1.6	0.3	-0.7	-1.1
Alzheimer’s Disease (including proxy)	1.2	1.7	6.3	-1.3	-0.3	-2.5	-1.4	0.5	1.4	0.5	-0.9	-1.5
Crohns Disease (2017)	1.8	4.0	11.2	2.4	3.3	1.9	0.2	-2.8	2.2	-0.3	-1.8	-0.5
Irritable Bowel Disease (IBD)	1.8	4.2	13.2	3.3	3.6	2.0	-0.2	-2.3	1.3	-0.6	-1.4	-0.6
Ulcerative Colitis (UC)	1.2	2.3	9.7	3.1	2.9	1.0	-0.2	-0.7	0.4	-0.7	-1.0	-0.3
Major Depression (MDD)	1.2	1.5	4.3	-1.2	-2.1	-1.1	0.7	0.2	-1.4	0.9	-1.6	0.0
Reaction Time	1.1	2.1	6.0	-0.5	-0.3	-2.1	-1.1	1.2	2.5	1.1	1.5	-1.3
Verbal and Numeric Reasoning (VNR)	1.1	2.7	8.1	1.9	1.9	0.3	0.5	-2.9	1.3	-1.4	-2.2	-0.2
Breast Cancer	0.3	0.7	2.1	-0.3	0.2	-1.1	0.2	-1.1	-0.2	-0.7	-1.4	-1.2
Ovarian Cancer	0.8	1.1	3.0	-0.8	-0.4	-0.0	1.3	1.7	-1.1	1.0	0.3	1.5
Prostate Cancer	1.4	2.0	8.8	1.9	1.1	0.4	0.5	-0.7	1.7	0.3	-3.0	-0.1
Age at First Birth	0.6	0.9	2.7	1.0	1.6	0.6	0.0	-1.0	-1.0	-0.4	-1.3	0.0
Bipolar Disorder (2011)	0.6	0.6	2.7	-0.1	0.2	-0.4	-0.9	-0.1	-0.2	-1.6	1.2	-0.6
Body Mass Index (BMI) (2010)	1.3	1.8	4.4	1.4	2.1	-0.7	-0.9	-0.8	1.7	0.8	-1.6	-1.2
Coronary Artery Disease (CAD)	1.2	1.4	2.9	-1.5	-1.5	-1.7	0.6	1.7	0.3	-0.2	-1.1	0.7
Crohns Disease (2012)	2.7	4.3	7.3	2.1	2.7	2.4	2.7	-1.6	0.9	0.2	-2.6	1.9
Mean Putamen Volume	2.0	2.3	5.5	-0.6	0.3	-2.3	-1.8	-0.4	-1.6	-1.8	0.7	-2.3
Fasting Glucose	1.1	1.4	4.1	-0.0	0.3	1.9	0.9	0.8	-1.0	-0.7	1.2	2.0
HbA1C	0.6	0.7	1.8	1.1	0.1	1.4	0.9	-1.3	0.3	0.3	-0.2	0.5
HDL Cholesterol	1.1	1.9	3.9	-0.1	-0.8	1.7	2.0	1.5	-1.6	-1.1	0.3	1.7
LDL Cholesterol	1.1	1.7	7.8	-0.9	-2.8	-1.5	-1.5	-0.0	-0.3	-0.7	0.1	-1.4
Lupus	0.1	0.1	0.2	0.5	0.1	-0.4	-0.4	0.1	0.0	-0.0	0.2	-0.3
Neuroticism (2016)	0.4	0.5	2.2	0.7	-0.7	-0.0	0.2	0.7	-0.7	-1.5	-0.0	0.7
Primary Biliary Cirrhosis	0.2	0.3	1.0	0.8	0.2	1.0	-0.5	0.6	0.2	-0.2	0.7	-0.1
Rheumatoid Arthritis	1.2	1.6	6.0	0.8	-0.3	1.6	1.7	0.5	0.6	-0.9	-0.9	2.5
Schizophrenia (2014)	1.4	3.0	9.9	-0.4	-1.7	0.3	-0.6	1.8	-3.0	-0.1	3.1	1.2
Triglycerides	0.8	1.2	3.2	1.2	0.3	-1.4	-1.1	-0.9	1.0	0.4	-1.2	-1.8
Type 2 Diabetes (T2D) (2012)	0.9	1.1	3.4	0.0	1.2	-0.5	-1.0	-0.3	1.8	1.5	0.7	-0.9
Ulcerative Colitis	2.6	3.7	13.3	3.6	3.7	1.7	-0.1	-1.5	-0.2	-0.2	-1.5	-0.6
Blood Eosinophil Count	0.3	2.3	6.8	-1.1	-0.8	-2.6	-1.9	0.8	-0.2	-1.0	-0.5	-2.6
Blood Platelet Count	2.0	23.0	47.6	-5.0	-6.9	-6.0	-4.9	6.3	-3.1	0.9	4.6	-1.7
Blood Red Count	0.4	3.5	8.4	0.4	0.4	-2.9	-1.8	-0.6	2.3	2.2	-0.9	-2.9
Blood White Count	0.2	1.2	6.1	0.1	-1.1	-1.8	-0.1	2.5	-0.5	-0.2	0.3	-0.6
Heel T-Score	0.2	1.8	6.3	1.2	0.1	-0.4	0.1	-2.1	1.8	0.2	-2.5	-1.1
BMI	0.2	0.9	3.3	1.8	1.1	1.1	0.8	-0.8	0.1	0.8	0.1	0.3
Height	0.2	3.2	10.7	-1.3	-1.7	-2.1	-1.5	-1.6	1.4	-3.3	-0.1	-1.4
Waist Hip Ratio (WHR)	0.2	0.9	4.2	0.1	0.3	0.7	0.8	0.2	-1.5	-2.0	0.7	0.7
Systolic Blood Pressure	0.6	3.0	5.9	-2.2	-1.6	-2.4	-2.4	-1.6	-0.2	0.8	-1.7	-1.4
Smoking Status	0.8	1.9	4.8	-0.6	-1.9	1.1	-0.6	0.9	-2.2	-2.0	1.1	1.1
Allergy or Eczema	0.4	1.0	5.9	0.3	-1.0	-0.8	0.6	-0.5	2.4	0.9	-0.5	0.1
Cardiovascular Disease	0.9	2.9	10.2	-3.2	-2.3	-2.7	-1.0	0.0	-0.8	0.9	0.4	0.4
Hypothyroidism (self reported)	1.0	2.2	11.7	-0.4	-0.3	-0.5	-3.4	-0.1	-0.3	1.5	0.9	-2.1
Respiratory disease	0.4	0.9	3.0	1.3	0.7	-1.7	-0.8	0.4	0.2	-1.3	0.2	-0.8
Type 2 Diabetes (T2D) (2018)	1.2	2.2	8.3	-1.3	0.9	1.3	2.9	-1.2	0.2	1.0	-1.3	1.9
Lung FEV1/FVC ratio	0.3	1.5	4.7	-0.7	0.4	1.0	1.1	-1.2	1.1	2.2	-1.7	0.8
Lung FVC	0.7	3.6	14.0	0.0	1.8	3.7	1.9	-0.8	-1.5	1.0	1.1	2.5
Neuroticism	0.3	0.6	2.8	1.7	0.0	0.6	-0.1	-0.0	0.3	-1.4	-0.9	-0.2
Chronotype (morning person)	0.2	0.5	1.4	1.1	0.1	-1.2	-0.6	0.5	0.3	0.9	0.4	-0.6
Hair Pigment	0.2	4.3	11.0	-0.3	0.8	3.3	3.3	-0.9	1.4	-0.4	-2.3	2.8
Tanning	0.1	0.8	3.0	0.8	-0.3	-0.8	-0.5	0.1	-1.7	0.4	-0.2	-1.5
Hand grip strength (left)	0.7	1.8	7.7	-0.6	-2.0	-0.2	-0.4	1.7	-2.8	-0.0	0.9	-0.1
Number of treatments/medications taken	0.3	0.5	2.3	0.6	-0.1	-1.5	0.6	0.4	-0.2	0.2	-1.0	-0.1
Average weekly spirits intake	1.4	1.7	5.2	-1.7	0.5	-0.1	1.5	-0.9	1.3	-1.1	-2.3	0.9
Sensitivity / hurt feelings	0.5	0.9	4.1	-0.5	-1.2	0.7	-0.1	1.0	-0.4	2.0	-0.5	0.8
Frequency of depressed mood in last 2 weeks	0.9	1.2	3.3	-0.6	-1.4	-0.5	1.1	1.3	0.5	-0.6	-1.4	1.8
Hearing difficulty/problems: Yes	0.7	1.0	4.0	0.4	-2.0	0.2	0.7	0.4	-2.0	0.6	0.1	0.5
Relative age of first facial hair	0.8	1.7	6.1	0.3	-0.4	0.1	-1.2	-2.5	-1.4	-0.2	-1.6	-1.6
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.8	1.4	0.4	0.5	-0.3	-0.2	-0.6	0.7	0.8	-0.7
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.5	1.2	1.2	1.1	-0.4	-0.4	1.2	-0.2	0.6	0.0
Ever had hysterectomy (womb removed)	0.5	0.6	1.3	0.6	0.8	1.1	0.9	-0.6	0.4	1.0	0.5	0.4
Systolic blood pressure, automated reading	0.5	1.6	6.2	-0.2	-0.7	-1.8	-2.5	-1.1	0.0	-0.5	-0.5	-1.6
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.1	-1.1	-0.5	-0.6	-0.9	0.4	0.3	-1.0	0.7	-0.8
Angina	0.7	0.9	3.6	-0.3	-0.4	0.3	1.7	1.9	0.1	-0.6	0.2	1.1
Medication for hormone replacement therapy	0.8	0.8	3.4	0.2	-1.4	0.1	0.6	0.6	-1.8	1.0	0.8	0.2
Vitamin and mineral supplements	1.0	1.4	3.5	-1.2	-0.4	1.2	0.6	-0.1	-1.2	-1.9	0.8	1.8
Supplements: Zinc	2.2	2.4	7.5	-2.7	-2.7	-1.1	0.7	0.4	-1.8	-0.2	1.1	0.7
Medication: Co-codamol	1.0	1.2	5.1	2.3	1.4	-0.5	0.5	0.7	0.5	0.1	-1.3	-0.4
Medication: Metformin	0.9	1.2	4.6	-0.2	0.3	0.4	1.7	-0.0	0.4	0.3	-2.1	1.7
Diabetes (father)	2.6	3.2	7.2	1.0	2.4	2.7	-0.1	-2.4	2.3	0.1	-2.0	-0.5
Diabetes (mother)	0.4	0.6	1.7	-0.0	0.6	-0.4	-0.8	0.5	1.3	1.0	0.8	-0.3
Severe depression (siblings)	0.2	0.2	0.7	-0.1	-0.7	0.1	-0.3	0.9	-0.2	0.5	0.5	-0.5
Pack years adult smoking proportion	0.8	1.3	5.9	-1.1	-2.4	-0.3	-0.4	1.8	-0.4	0.4	0.7	0.3
Impedance of leg (right)	0.4	2.1	8.4	-0.7	-0.7	-2.9	-1.0	2.2	0.9	-0.4	1.3	-1.1
Leg fat-free mass (left)	0.2	0.9	2.9	0.1	-0.1	1.7	0.3	-1.5	-1.5	-0.2	0.1	0.5
Trunk fat percentage	0.1	0.4	1.1	1.0	0.1	-0.3	0.1	0.4	0.9	-1.0	0.4	-0.0
Hand grip strength (right)	0.9	2.5	6.6	-1.3	-2.5	0.8	0.8	1.5	-2.6	-1.3	1.1	1.3
Townsend deprivation index at recruitment	0.5	0.6	1.8	0.6	0.1	1.2	0.5	-0.0	0.6	1.4	-1.2	-0.3
Current tobacco smoking	0.6	1.0	3.9	-0.8	-2.0	1.2	0.7	0.4	-0.9	-0.3	-0.4	1.0
Average weekly fortified wine intake	0.8	0.9	3.9	0.5	0.5	-0.4	-2.0	-0.4	1.0	0.4	0.8	-1.2
Maternal smoking around birth	1.5	2.1	9.9	0.7	0.1	3.1	1.6	-0.7	-1.2	0.3	1.0	1.8
Fed-up feelings	1.0	1.9	3.6	1.0	0.2	1.1	1.9	0.9	1.2	1.6	-1.7	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.1	0.0	-0.6	-0.0	1.0	-0.4	0.5	-0.3	-0.9	0.8
Relative age voice broke	0.5	0.8	1.8	-0.4	-0.8	-0.8	-1.3	-0.5	-1.2	-0.3	-0.8	-1.3
Taking other prescription medications	0.5	0.8	2.3	0.4	0.9	-0.8	-1.4	0.1	0.6	1.0	-0.4	-1.5
Age when periods started (menarche)	2.6	6.2	13.5	1.4	2.9	2.5	1.9	-3.7	3.0	0.9	-3.2	1.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.9	-0.0	-0.0	1.0	1.4	0.7	0.3	0.0	0.1	1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.7	7.0	0.8	0.8	-0.8	-0.6	-1.4	2.6	0.3	-2.0	-0.5
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	7.1	0.1	-0.2	-0.4	0.4	0.5	1.3	2.7	0.0	-0.3
Qualifications: CSEs or equivalent	1.0	1.3	3.6	0.6	0.5	0.6	1.5	-1.2	-0.6	1.9	-0.1	1.8
Serious illness, injury or assault to yourself	0.8	1.0	2.7	1.1	-0.7	-1.4	-0.5	-1.1	-0.5	-0.2	-0.7	-1.7
High blood pressure	0.4	1.1	3.9	-1.2	-2.0	-1.6	-0.8	0.4	-0.9	-0.1	0.4	-0.1
Hayfever, allergic rhinitis or eczema	0.5	1.0	3.8	0.9	-0.5	-0.1	0.5	0.4	2.0	1.9	0.3	0.4
Multivitamins +/- minerals	1.5	1.9	4.6	1.1	1.1	-0.4	-0.3	-1.3	2.1	1.5	-2.0	-1.3
Stomach or abdominal pain in last month	1.3	1.7	4.2	0.4	-0.2	-1.9	-2.0	0.4	1.6	-0.3	-0.3	-2.0
Supplements: Glucosamine	0.5	0.7	2.5	-1.1	-1.0	-0.6	-0.8	0.4	0.1	-1.6	-0.0	0.0
Diverticular disease/diverticulitis (self-reported)	3.7	4.4	10.0	-1.0	-1.0	-2.6	-2.6	0.8	-2.3	0.4	2.9	-3.2
Medication: Atenolol	2.5	3.2	8.7	-2.5	-3.0	-2.2	-1.0	1.7	-1.2	-1.3	1.1	0.3
Medication: Levothyroxine sodium	1.0	1.7	4.9	-0.0	-0.8	-1.0	-2.2	-0.2	0.6	1.9	0.2	-2.2
Sitting height	0.7	4.8	12.5	-2.1	-2.5	-0.4	-2.3	0.9	-2.6	-2.6	3.5	-0.7
Chronic bronchitis/emphysema (father)	1.3	1.6	6.6	-0.9	-2.6	0.4	1.0	1.4	-1.1	0.4	0.5	1.3
High blood pressure (mother)	1.2	1.7	4.4	-1.9	-1.8	-2.1	-0.6	1.5	-0.8	1.1	0.5	0.0
Body mass index (BMI)	0.1	0.6	1.4	1.1	0.2	1.2	0.7	0.5	-0.7	0.7	0.5	0.7
Impedance of leg (left)	0.5	2.2	7.7	-0.9	-1.1	-2.8	-0.8	2.2	1.2	-0.8	1.2	-1.0
Leg predicted mass (left)	0.2	0.8	2.8	0.3	-0.0	1.7	0.2	-1.6	-1.4	-0.2	0.0	0.4
Trunk fat mass	0.1	0.2	1.1	0.9	-0.1	0.2	0.2	0.1	0.2	-1.1	0.5	0.0
Waist circumference	0.1	0.4	2.1	1.5	0.2	0.6	0.8	0.2	-0.7	-0.3	-0.1	0.1
Number of incorrect matches in round	1.5	2.5	5.8	-0.8	-1.5	0.9	1.7	1.9	-1.5	-1.4	1.3	2.4
Past tobacco smoking	0.5	0.8	3.7	1.0	1.3	-0.2	0.4	0.2	0.5	1.9	0.1	-0.8
Alcohol usually taken with meals	0.6	1.0	3.3	-1.4	-0.8	-0.7	-0.8	1.1	-0.2	-1.0	1.8	-0.3
Nervous feelings	1.3	2.4	6.4	-1.0	-1.9	0.0	-1.5	2.3	-0.3	-1.5	2.5	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	2.4	-0.9	-1.3	0.5	-0.5	1.5	1.4	1.2	0.7	0.2
Hearing difficulty/problems with background noise	1.0	1.6	6.5	-0.1	-1.4	1.4	-0.0	0.4	-2.5	-0.8	1.3	1.1
Hair/balding pattern: Pattern 2	0.6	0.8	4.7	0.1	0.1	0.7	-0.5	-0.2	-0.9	2.2	1.0	-0.3
Had menopause	0.2	0.2	0.7	0.8	0.9	0.0	-0.2	-0.6	0.5	0.2	0.2	0.2
Had other major operations	0.4	0.5	2.2	1.5	0.5	0.2	0.1	-0.2	0.2	-0.1	-1.4	0.2
Forced vital capacity (FVC)	0.4	1.6	4.5	-0.5	0.8	2.1	1.4	-1.8	-1.5	-0.1	0.1	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	2.6	-0.7	-0.5	-0.9	-0.2	-0.1	1.6	0.7	-1.0	0.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.6	1.2	0.0	0.0	-0.8	0.6	0.1	-0.3	-0.7	-0.4
Qualifications: None of the above	0.1	0.3	0.7	0.5	-0.6	0.1	-0.7	0.8	0.5	0.6	0.1	-0.3
Financial difficulties in last 2 years	0.4	0.5	3.1	0.1	-0.1	0.3	0.3	-0.1	0.8	1.8	-0.9	0.2
Mouth/teeth dental problems	0.5	0.8	2.7	-1.6	0.8	1.0	-0.4	0.9	0.8	-0.9	0.5	0.3
Heart attack	1.0	1.2	7.8	-0.9	-0.4	-2.8	-0.4	0.3	1.2	-0.2	0.2	-0.8
Allergy	0.6	1.3	5.1	-0.5	0.1	0.3	-0.7	-0.9	-1.9	-2.3	-0.7	-1.0
Pain all over the body in last month	1.0	1.1	3.6	1.5	0.3	-1.2	-0.4	-0.1	-0.5	-1.0	-1.0	-1.9
Diabetes (self-reported)	1.5	2.2	7.5	-0.4	0.9	1.7	2.7	-0.7	-0.3	1.6	-0.8	2.2
Hayfever/allergic rhinitis (self-reported)	2.3	3.0	10.4	3.2	2.3	0.9	0.7	-1.2	2.1	0.2	-2.1	-0.0
Medication: Ramipril	1.2	1.5	6.2	-2.5	-1.9	-1.2	0.3	1.1	-0.4	-0.1	0.7	0.5
Medication: Simvastatin	0.9	1.3	4.8	-2.0	-1.3	-2.2	0.7	0.7	0.7	-0.1	0.2	0.2
Fluid intelligence score	0.4	0.8	2.0	0.2	0.1	0.4	1.4	-0.8	-0.4	-1.3	-1.0	1.3
Illnesses of siblings	0.4	0.6	2.4	-0.7	-0.1	0.5	0.2	-1.5	0.8	-1.1	-0.7	0.0
Neuroticism score	0.3	0.6	1.4	0.6	-1.0	0.8	-0.3	1.1	-0.8	-1.2	0.4	0.5
Weight	0.1	0.3	1.0	0.6	-0.4	1.0	0.1	-0.0	-0.8	-0.5	0.6	0.2
Impedance of arm (right)	0.4	1.7	4.4	0.4	1.3	-1.5	-0.5	-0.5	2.1	-2.1	-1.1	-1.1
Arm fat percentage (right)	0.1	0.6	2.8	1.7	0.9	0.7	0.6	0.2	0.1	-0.6	-0.1	0.2
Trunk fat-free mass	0.2	1.1	4.2	-0.5	-0.7	2.1	0.1	-0.6	-1.8	-0.5	0.9	0.6
Hip circumference	0.1	0.5	1.5	0.9	-0.4	-0.2	-0.3	0.6	-1.1	0.4	1.2	-0.6
Time employed in main current job	0.5	0.6	2.1	0.7	-0.5	-0.2	-1.4	-0.1	-0.7	-0.4	0.9	-0.8
Alcohol intake versus 10 years previously	0.2	0.3	0.8	0.3	0.2	-0.1	-0.6	-0.8	0.9	-0.4	0.7	0.2
Father’s age at death	0.1	0.2	0.7	0.4	-0.2	-0.6	-0.3	-0.0	-0.1	-0.2	-0.4	-0.8
Worrier / anxious feelings	0.2	0.4	0.9	1.0	0.0	0.2	0.8	-0.3	0.7	-0.9	-0.5	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.6	0.2	-1.1	-0.8	1.3	1.0	0.2	0.1	-0.6	-0.1
Falls in the last year	1.1	1.5	5.4	1.2	0.1	0.5	1.0	-0.8	0.1	-1.9	-2.3	1.2
Hair/balding pattern: Pattern 3	0.1	0.2	0.7	0.2	0.0	0.2	0.7	-0.1	-0.2	-0.2	-0.9	-0.5
Number of live births	0.8	1.1	2.6	1.5	1.0	-0.2	-1.6	-0.7	0.6	1.4	0.8	-0.7
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	3.5	-0.7	0.9	1.8	0.9	-1.9	-1.0	0.7	-0.5	1.0
Pulse rate	0.9	1.5	4.0	-0.0	-0.6	0.7	1.9	1.6	-0.6	-1.3	-0.0	2.0
Happiness	0.9	1.0	2.5	-1.0	-1.5	-1.6	0.0	-0.7	0.7	0.2	-1.4	-0.7
Noisy workplace	1.2	1.4	4.8	0.5	-0.0	1.4	1.6	0.1	-0.9	2.2	-0.6	1.6
Qualifications: A levels/AS levels or equivalent	0.4	1.0	3.3	-1.1	0.3	-1.2	-0.6	-0.6	-0.3	-1.8	0.7	-1.1
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	3.5	1.9	1.2	0.1	-1.6	-0.3	-0.1	-1.0	0.2	-1.4
Mouth/teeth dental problems: Dentures	0.5	0.8	2.2	0.7	-1.0	-1.1	0.5	0.9	-1.5	1.0	-0.5	-0.2
Asthma	0.5	1.0	3.3	1.4	1.8	-1.0	-0.1	-0.2	1.4	0.0	-0.2	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.8	0.5	0.3	0.9	0.7	-0.3	0.2	0.7	-0.9	0.2
Medication: Cholesterol lowering	0.8	1.2	2.7	-1.4	-0.8	-1.1	1.6	1.4	-0.2	-0.9	0.8	1.0
Depression (self-reported)	0.6	0.7	2.2	0.8	-1.0	-0.2	0.4	0.2	1.0	0.1	-1.5	1.1
Medication: Lansoprazole	0.5	0.6	4.0	-0.6	-2.0	-0.5	-0.0	0.7	-0.0	-0.2	0.3	0.0
Prospective memory result	1.5	1.8	4.5	-1.9	-1.4	0.0	0.7	2.1	0.1	1.7	1.4	1.1
Lung cancer (father)	0.7	0.8	3.3	0.2	-0.2	0.7	0.1	-1.8	-0.6	-1.2	-1.2	0.4
Illnesses of mother	0.7	0.9	4.1	2.0	0.5	0.6	0.7	-1.0	-0.0	0.0	-0.9	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	2.5	-0.3	0.4	1.6	0.3	-1.4	-1.0	0.3	0.2	0.6
Pulse wave Arterial Stiffness index	1.1	1.2	3.8	1.0	0.2	-0.4	-1.1	-2.0	1.1	0.2	-1.1	-1.6
Impedance of arm (left)	0.3	1.5	4.6	0.1	0.8	-2.1	-0.4	-0.2	1.8	-1.7	-1.0	-1.2
Arm fat mass (right)	0.1	0.4	1.3	0.9	0.2	1.1	0.7	0.2	-0.6	-0.6	0.4	0.6
Trunk predicted mass	0.2	1.3	4.8	-0.6	-0.7	2.2	0.2	-0.6	-1.9	-0.5	0.9	0.7
Standing height	0.2	1.7	7.8	-1.1	-1.3	0.0	-1.3	-0.9	-0.5	-2.8	0.7	-0.9
Length of working week for main job	0.5	0.6	2.1	0.1	-0.3	1.5	-0.4	-1.3	0.1	-0.0	1.1	-0.1
Exposure to tobacco smoke at home	0.8	0.8	2.5	-1.0	-0.5	0.7	0.1	1.6	-0.8	-0.1	1.4	1.0
Breastfed as a baby	0.2	0.2	0.7	-0.5	-0.4	-0.1	-0.2	-0.9	-0.6	-0.8	-0.4	0.1
Tense / ‘highly strung’	2.0	3.3	12.3	-0.6	-1.7	-1.9	-3.5	1.2	0.9	-0.5	1.9	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	2.2	-0.2	-0.4	1.0	-0.4	0.8	0.9	1.5	-1.1	0.7
Hair/balding pattern: Pattern 4	0.5	1.2	4.9	-0.6	-0.8	0.8	0.6	0.0	-0.9	-2.2	-1.2	1.2
Birth weight of first child	0.6	1.0	2.8	1.3	0.4	-0.3	0.7	-0.5	1.0	1.7	-0.8	-1.4
Peak expiratory flow (PEF)	0.2	0.5	2.3	-0.4	0.2	0.9	0.1	-1.5	-0.9	0.4	-0.3	0.5
Pulse wave reflection index	1.0	1.3	4.8	0.8	0.2	-1.4	-1.4	-0.8	-0.3	1.1	-0.4	-2.2
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.6	0.3	0.2	-0.2	-1.1	-1.6	-0.4	-0.6	-0.8	-1.0
Loud music exposure frequency	0.5	0.5	2.2	0.2	-0.1	0.5	-0.7	-1.5	0.6	0.8	-0.3	-0.8
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	3.6	-0.3	0.6	0.2	-1.1	0.2	-0.7	-1.9	0.9	-0.8
Mouth/teeth dental problems: Bleeding gums	1.5	1.9	7.1	1.8	0.8	-0.1	-1.4	-2.7	-0.2	-1.1	-0.3	-1.8
Blood clot in the leg (DVT)	0.6	0.8	2.2	-0.9	0.3	0.8	0.4	-1.5	-0.6	1.4	0.8	0.4
Medication: Paracetamol	0.4	0.7	2.7	0.6	-0.0	0.2	1.4	0.1	0.1	1.7	-0.9	-0.1
Headache pain in last month	1.0	1.8	5.9	-1.8	-1.3	-0.5	0.7	2.4	0.2	1.6	1.1	0.8
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	1.5	1.2	-0.2	0.4	-0.9	0.4	-1.1	0.1	-0.0	-0.3
Glaucoma (self-reported)	3.7	4.3	12.6	2.5	1.8	3.6	2.7	-1.4	1.2	-0.2	-2.2	1.2
Gout (self-reported)	1.2	1.6	3.5	-1.0	-1.9	-0.7	0.6	1.4	-1.3	1.6	1.6	0.4
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	7.6	0.5	0.2	-0.5	-2.8	-0.4	0.5	1.7	0.0	-2.0
Medication: Amlodipine	2.7	3.7	8.2	-1.8	-2.1	-0.0	1.4	1.2	-2.5	-2.9	0.4	2.9
Medication: Ventolin 100micrograms inhaler	0.5	0.7	3.3	-0.4	0.3	-0.2	-0.4	-0.3	-1.4	-1.8	-0.3	0.1
Birth weight	0.7	1.5	2.9	0.3	0.9	1.0	1.3	-1.5	1.2	1.7	-1.7	-0.7
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.4	-0.3	0.4	0.5	-1.2	-0.3	-0.7	-0.4	0.6	-0.4
High blood pressure (siblings)	0.6	0.8	3.7	0.2	-0.8	-0.1	0.2	1.9	-0.7	1.4	0.8	-0.0
Forced vital capacity (FVC), Best measure	0.3	1.0	3.3	-0.6	-0.0	1.5	0.6	-1.3	-1.8	-0.5	0.4	0.6
Body fat percentage	0.1	0.4	1.9	1.4	0.3	-0.1	0.4	0.6	0.5	-0.7	0.2	0.1
Leg fat percentage (right)	0.2	0.6	3.3	1.8	0.3	-0.2	0.5	1.1	-0.2	0.8	0.2	-0.1
Arm fat-free mass (right)	0.2	1.0	2.5	-0.7	-1.1	1.5	-0.0	-0.5	-1.6	-0.2	1.3	0.6
Exposure to tobacco smoke outside home	1.1	1.4	4.9	-0.9	-1.1	2.2	0.8	0.6	0.5	0.2	1.2	1.7
Comparative body size at age 10	1.1	3.1	7.2	1.5	2.7	2.3	1.7	-1.2	0.9	2.1	-1.8	0.6
Number of full brothers	0.8	1.0	2.7	1.3	0.7	-1.1	-1.2	-0.2	0.3	0.6	-1.1	-1.6
Worry too long after embarrassment	0.1	0.2	0.8	-0.1	-0.1	0.9	-0.5	-0.6	0.3	0.1	-0.6	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.9	1.0	1.3	0.3	-0.9	0.2	1.4	0.0	-0.7	-0.4
Wheeze or whistling in the chest in last year	0.2	0.4	1.5	1.2	0.3	0.1	0.1	1.2	0.6	-0.2	-0.7	0.0
Number of children fathered	0.2	0.3	1.0	0.4	0.2	1.0	0.0	-0.3	-0.1	-0.8	-0.7	0.1
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	4.3	-2.1	-1.4	-0.7	-0.2	0.4	1.0	-2.0	0.4	0.4
Age at first live birth	1.7	3.0	7.8	-2.8	-2.0	-0.2	-0.9	0.5	-1.4	-2.2	2.5	0.7
Pulse wave peak to peak time	1.0	1.1	3.2	-0.9	-0.4	0.5	0.8	1.8	-1.2	-0.4	1.2	1.4
Health satisfaction	1.2	1.5	4.3	0.8	0.4	1.3	1.2	-1.2	0.7	1.2	-1.5	2.1
Shortness of breath walking on level ground	0.7	0.9	3.5	0.4	0.8	1.9	0.5	0.1	-1.1	0.4	1.0	0.9
Qualifications: College or University degree	0.4	1.2	3.5	-1.9	-1.8	-1.2	0.5	-0.9	-0.5	-1.0	0.5	-0.6
Eye problems/disorders: None of the above	1.2	1.4	3.1	-1.6	0.4	-0.8	-1.8	1.3	-0.5	1.1	1.6	0.1
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.8	0.2	-0.7	-0.2	-1.4	0.2	0.7	0.1	0.5	0.0
Emphysema/chronic bronchitis	0.9	1.0	2.4	-1.1	-1.6	-0.2	0.8	1.5	-0.8	0.4	-0.0	1.5
Medication for pain relief, constipation, heartburn	0.4	0.7	2.3	0.1	0.7	0.8	-1.1	-0.2	-0.1	-1.5	1.1	0.1
Neck or shoulder pain in last month	0.6	0.8	3.4	1.0	0.2	-1.1	-0.2	1.8	1.1	-0.3	0.3	0.5
Medication: Blood pressure	0.5	0.8	3.5	-1.9	-1.1	-0.7	1.0	-0.6	0.5	-0.7	0.0	0.5
Angina (self-reported)	0.8	1.1	3.8	-0.5	-0.7	0.1	1.9	1.9	0.0	-0.6	0.3	1.2
Migraine (self-reported)	0.6	0.8	3.1	-0.2	-1.0	-1.0	-1.8	0.2	0.7	0.3	0.4	-1.0
Medication: Ibuprofen	0.4	0.5	1.9	1.4	0.9	0.7	0.2	-0.4	-0.1	-0.6	-0.7	-0.5
Medication: Allopurinol	0.4	0.5	1.0	-0.7	-0.9	-0.8	0.5	0.3	-0.3	1.0	1.0	0.2
Medication: Omeprazole	1.6	1.9	4.9	1.3	0.6	-1.0	-1.5	-1.7	0.5	0.7	-1.8	-2.2
Medication: Seretide 50 evohaler	0.6	0.7	2.9	-0.4	-0.2	-0.7	-0.9	-0.0	-1.7	1.1	-0.0	-0.6
Mean time to correctly identify matches	0.7	1.3	6.3	0.4	0.6	-1.3	-0.9	-0.0	2.5	0.4	0.9	-1.2
Heart disease (mother)	1.3	1.6	4.4	-2.0	-0.9	-1.8	0.1	2.1	-0.1	1.3	0.8	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.3	2.8	7.7	-2.5	-2.8	-1.0	1.3	2.0	-1.6	0.4	0.5	1.3
Whole body fat mass	0.1	0.2	1.0	1.0	-0.1	0.4	0.5	0.2	-0.2	-0.7	0.3	0.2
Leg fat mass (right)	0.1	0.4	1.3	1.1	-0.2	0.5	0.8	0.5	-0.7	0.4	0.3	0.3
Arm predicted mass (right)	0.2	1.2	2.7	-0.9	-1.5	1.6	0.3	-0.2	-1.6	-0.2	1.4	0.9
Pulse rate, automated reading	0.8	2.6	8.2	0.7	1.0	1.7	2.9	0.3	1.2	0.3	-1.1	2.7
Alcohol intake frequency.	1.2	2.9	5.8	0.6	0.1	-2.4	-1.2	2.0	1.9	2.1	0.9	-2.3
Comparative height size at age 10	0.3	1.8	4.7	-1.2	-1.7	-1.0	-1.8	-0.3	-0.6	-2.2	1.0	-1.1
Number of full sisters	0.4	0.5	1.1	0.7	0.7	1.1	0.4	0.7	0.8	0.5	-0.8	0.7
Suffer from ‘nerves’	1.0	1.5	7.1	-0.4	-1.9	-0.6	-0.9	2.7	-0.5	-0.4	1.1	0.0
Overall health rating	0.5	1.1	2.8	1.6	0.3	-0.7	0.2	-0.2	1.0	1.2	-1.7	-1.0
Chest pain or discomfort	0.4	0.5	1.5	-0.0	-0.5	0.7	0.6	1.0	-0.3	1.0	0.2	1.2
Had major operations	1.0	1.1	4.9	-0.4	-0.2	-0.3	1.4	-0.4	0.0	1.6	-2.2	-0.3
Age at last live birth	1.0	1.5	6.6	-1.4	-1.1	-0.3	-1.0	0.6	-1.3	-0.3	2.6	0.6
Family relationship satisfaction	1.1	1.3	5.9	0.9	0.9	0.3	0.5	-1.8	0.8	0.2	-2.4	0.4
Leg pain on walking	0.5	0.6	1.8	1.1	0.6	-0.5	0.1	-0.4	1.0	0.2	-1.4	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	2.4	-0.3	0.3	-0.3	-0.3	0.6	1.0	-0.2	-1.6	0.1
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.4	0.1	-0.1	-0.3	-0.8	-0.5	-0.7	-1.2	-0.6	-0.5
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.9	-0.7	0.8	1.2	0.4	-0.1	-0.8	-0.7	0.8	1.4
Medication: Aspirin	0.5	0.6	1.5	-0.9	-0.9	-1.1	0.1	1.2	-1.0	-0.3	0.6	0.3
Supplements: Vitamin C	1.6	1.8	5.5	-0.9	-1.4	-0.3	1.8	2.3	-1.0	1.1	1.2	1.2
Knee pain experienced in last month	1.1	1.7	4.4	2.1	0.5	1.1	1.7	-0.5	0.0	-0.6	-1.7	1.7
Hypertension (Self-reported)	0.6	1.7	5.3	-1.6	-2.3	-1.7	-1.4	0.3	-1.1	-0.6	0.8	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	4.4	-0.1	-1.4	-0.6	-0.9	-0.6	-0.4	-2.1	0.5	-0.9
Illnesses of father: Heart disease	1.4	2.0	7.2	-1.9	-0.7	-0.9	-1.4	0.6	-1.4	-1.2	2.7	-0.1
Illnesses of siblings: Diabetes	0.7	0.9	2.7	0.5	1.6	1.3	-0.8	-1.3	0.8	0.3	-0.4	0.2
Smoking status: Previous	0.3	0.5	2.5	-0.3	-0.7	-0.5	-1.0	0.3	0.1	-1.6	0.4	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	6.2	-1.5	-0.6	-1.4	-1.2	-0.1	0.4	-2.5	0.9	-1.0
Whole body fat-free mass	0.2	1.0	3.9	-0.3	-0.5	2.0	0.1	-1.1	-1.7	-0.4	0.6	0.5
Leg fat-free mass (right)	0.2	0.9	3.6	0.0	-0.2	1.9	0.3	-1.7	-1.3	-0.2	-0.1	0.4
Arm fat percentage (left)	0.1	0.4	1.9	1.4	0.7	0.4	0.7	0.3	0.1	-0.4	0.1	0.2
Average weekly red wine intake	1.8	2.7	8.9	-1.6	-0.4	-0.8	-3.0	0.1	0.2	-1.2	2.4	-2.1
Handedness (chirality/laterality): Left-handed	1.4	1.7	3.9	0.1	-0.1	-0.9	-1.3	1.2	-1.9	1.5	2.0	-1.1
Mood swings	0.3	0.5	1.3	0.5	-0.7	1.1	0.5	0.1	-0.0	-0.8	-1.1	0.8
Loneliness, isolation	0.6	0.8	2.3	-0.5	-1.0	-1.2	0.5	1.5	0.1	1.3	-0.3	-0.1
Long-standing illness, disability or infirmity	0.7	1.0	2.0	1.0	-0.2	-1.2	-0.7	1.4	-1.3	1.1	0.1	-1.1
Ever had bowel cancer screening	0.5	0.5	1.2	1.1	0.2	-0.8	-1.1	-0.5	-0.4	-0.4	0.5	-1.1
Diabetes diagnosed by doctor	1.4	2.4	8.6	-0.3	0.8	1.6	2.9	-0.5	-0.0	1.4	-1.6	2.2
Ever had stillbirth, spontaneous miscarriage or termination	2.1	2.3	6.1	-1.7	-2.5	-0.6	-2.0	0.6	1.1	0.6	2.0	-1.1
Friendships satisfaction	1.8	2.3	5.2	0.6	1.4	-1.1	-0.6	-2.3	1.9	-1.2	-2.0	-1.5
Qualifications: nursing, teaching	1.9	3.0	16.1	-1.2	-1.4	-0.5	-0.7	1.5	-1.9	-0.5	4.0	0.3
Commuting to job workplace: Walk	0.6	0.6	2.5	0.5	0.9	0.7	0.2	-1.2	0.3	1.6	0.2	0.3
Eye problems/disorders: Cataract	0.6	0.7	1.8	0.5	-1.2	-1.1	-0.0	0.3	1.1	-0.7	-0.2	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	4.0	0.5	-0.2	0.4	-0.1	-0.3	0.4	2.0	0.4	-0.3
Medication for cholesterol	1.5	2.3	6.4	1.3	1.5	2.5	1.0	-2.4	1.3	0.2	-1.3	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.0	-1.4	-0.9	0.8	0.4	-0.8	-0.5	-0.1	-0.5	1.0
Back pain experienced in last month	0.9	1.3	4.0	1.9	-0.1	-1.1	0.5	0.1	2.0	0.7	-1.4	-0.2
Mineral and other dietary supplements	0.5	0.7	1.2	0.2	0.8	1.0	1.1	0.2	-1.1	1.0	0.3	0.9
Breast cancer (self-reported)	0.4	0.5	2.1	0.1	-0.3	-1.4	-0.6	0.5	0.7	0.2	-0.2	-1.0
Asthma (self-reported)	0.6	1.3	4.1	1.7	2.0	-0.9	-0.2	-0.3	1.7	-0.4	-0.6	-0.3
Osteoporosis (self-reported)	1.1	1.3	4.7	-0.1	1.3	0.2	-0.1	-2.2	1.9	-0.5	-1.2	0.2
Osteoarthritis (self-reported)	0.3	0.4	1.1	0.8	-1.0	-0.7	0.1	0.9	-0.5	0.3	-0.1	-0.5
Medication: Aspirin	0.4	0.5	1.4	-0.7	-1.0	-0.9	-0.0	0.9	-1.2	-0.3	0.5	0.1
Medication: Gliclazide	1.4	1.6	4.9	-2.2	-1.7	-0.9	0.6	0.7	-0.3	2.0	0.1	0.9
Illnesses of father: None of the above (group 1)	1.6	2.0	4.6	2.1	2.2	-0.1	-0.5	-1.1	1.5	1.2	-0.7	-1.8
Smoking status: Current	0.6	0.9	3.6	-0.8	-1.9	1.1	0.6	-0.1	-1.2	-0.3	-0.5	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	1.2	-1.1	-0.3	0.6	0.9	0.8	-1.1	0.7	0.5	1.0
Whole body water mass	0.2	1.1	3.9	-0.3	-0.6	2.0	0.0	-1.0	-1.8	-0.5	0.7	0.5
Leg predicted mass (right)	0.2	0.9	3.3	-0.0	-0.2	1.8	0.3	-1.6	-1.3	-0.3	-0.0	0.5
Arm fat mass (left)	0.1	0.4	1.1	1.0	0.1	1.0	0.7	0.2	-0.5	-0.4	0.4	0.5
Number of self-reported non-cancer illnesses	0.2	0.3	0.8	0.8	0.4	-0.4	0.5	-0.4	0.9	-0.4	-0.6	0.5
Average weekly champagne plus white wine intake	1.0	1.4	4.6	-0.4	-1.6	-0.7	1.5	1.2	-2.1	-0.7	0.2	0.9
Miserableness	0.2	0.3	1.2	0.7	0.0	1.1	0.4	0.2	0.0	0.1	0.0	0.9
Guilty feelings	1.1	1.7	7.0	1.1	0.9	2.6	1.0	-0.3	0.6	-1.0	-0.4	1.8
Wears glasses or contact lenses	0.8	0.9	4.9	-0.0	0.1	0.4	-1.4	0.0	2.2	-0.8	0.2	0.5
Ever taken oral contraceptive pill	0.9	1.0	2.0	-0.0	0.3	-0.9	-1.2	1.4	0.5	-0.8	1.4	-1.2
Hearing aid user	0.4	0.5	1.2	-1.1	-0.9	0.1	-0.4	0.5	-0.9	0.3	0.8	0.3
Mother’s age at death	1.0	1.2	3.7	-1.5	-1.0	0.6	0.3	0.8	1.4	-1.9	-0.3	0.9
Financial situation satisfaction	0.7	0.8	4.1	0.3	0.8	0.6	-0.5	-1.3	0.1	0.5	-2.0	-0.5
Tinnitus: Yes, now most or all of the time	1.3	1.6	5.3	-1.3	-2.3	-2.2	-0.4	1.0	-0.2	0.7	-0.1	-0.6
Commuting to job workplace: Public transport	0.8	0.9	2.2	0.1	0.7	1.1	1.5	0.9	0.9	0.8	0.0	1.4
Eye problems/disorders: Glaucoma	2.8	3.3	6.4	2.3	1.4	2.5	1.5	-2.1	1.7	-0.9	-2.3	0.5
Medication: Blood pressure	1.0	1.8	4.3	-1.2	-1.9	-2.1	-1.0	1.6	-1.4	-1.2	0.3	0.4
Pain type(s) experienced in last month: Hip pain	1.0	1.3	5.0	-0.2	-1.3	-1.3	0.1	2.2	0.1	1.3	1.2	0.2
Supplements: Fish oil (including cod liver oil)	1.4	1.8	4.3	-0.3	-1.6	-2.0	-2.1	0.8	0.7	-1.4	0.0	-1.5
High cholesterol (Self-reported)	0.9	1.6	6.4	-1.1	-0.2	-2.5	-0.3	0.1	0.4	-2.1	0.4	-1.4
Medication: Bendroflumethiazide	0.5	0.7	1.9	-0.6	-1.2	-1.4	-0.0	0.4	-1.3	-0.9	-0.5	0.3
Medication: Paracetamol	0.9	1.3	4.2	2.0	0.9	0.2	1.9	-0.1	0.2	0.8	-1.6	-0.4
Medication: Lisinopril	0.5	0.7	1.6	0.4	0.5	1.1	0.9	-1.3	-0.1	-0.9	-1.0	0.7
Medication: Atorvastatin	0.5	0.7	2.7	-0.2	0.6	-0.7	-0.3	-0.5	0.3	-1.3	-1.6	-0.5
Illnesses of father: High blood pressure	1.3	1.7	4.2	0.8	-0.5	-1.7	-2.0	-0.2	-0.7	-0.1	-1.6	-1.9
Alcohol drinker status: Never	1.9	2.2	6.2	0.4	-1.1	-0.2	1.4	2.1	-2.5	2.3	0.4	0.9
Ever smoked	0.8	1.4	3.5	-1.9	-1.8	0.6	-0.0	0.3	0.0	-1.6	-0.4	1.5
Basal metabolic rate	0.1	0.8	3.2	-0.1	-0.5	1.8	0.2	-0.8	-1.6	-0.4	0.6	0.5
Leg fat percentage (left)	0.1	0.5	3.1	1.8	0.2	-0.0	0.6	1.0	0.0	0.5	-0.0	-0.1
Arm fat-free mass (left)	0.2	1.1	4.5	-0.2	-0.8	2.1	-0.0	-0.4	-1.6	-0.4	1.2	0.6
Number of operations (self-reported)	0.2	0.3	2.5	0.2	-0.1	-0.3	0.5	-0.4	0.2	0.3	-1.6	0.0
Average weekly beer plus cider intake	0.7	1.1	3.1	0.5	-0.7	-1.5	-1.8	0.3	-0.5	-0.3	1.3	-1.2
Irritability	0.5	0.9	4.1	2.0	-0.1	0.8	-0.5	0.2	-0.2	-1.6	0.2	-0.4
Risk taking	0.6	0.9	5.0	0.2	-1.5	0.4	-0.0	-0.6	-2.2	0.3	0.1	-0.6
Ever had prostate specific antigen (PSA) test	0.5	0.6	5.0	-0.1	0.2	0.3	0.5	0.2	0.2	-2.2	0.1	0.5
Fractured/broken bones in last 5 years	0.8	1.1	3.0	-1.6	-1.4	0.1	1.2	0.3	-0.2	-0.7	-0.1	1.7
Age started oral contraceptive pill	0.8	1.0	4.6	-0.6	0.2	1.2	1.2	-0.2	0.8	-0.6	-0.0	2.1
Diastolic blood pressure, automated reading	0.5	1.6	7.0	-0.7	-0.7	-1.3	-2.6	-1.1	-0.8	-0.5	-0.5	-1.5
Ever depressed for a whole week	0.3	0.4	0.8	0.6	0.6	-0.9	-0.9	0.7	-0.4	-0.5	-0.2	-0.7
Unable to work because of sickness or disability	1.1	1.4	7.3	-0.2	-1.4	-0.9	0.1	0.9	-0.7	2.7	0.8	-0.1
Commuting to job workplace: Cycle	0.2	0.3	0.8	-0.4	0.5	-0.1	-0.8	-0.2	0.3	-0.4	0.3	-0.9
Myopia	2.0	2.8	8.3	2.1	2.9	1.2	0.9	-0.9	2.5	1.4	-1.2	0.1
Vascular/heart problems diagnosed by doctor	0.7	1.9	6.2	2.0	2.3	2.5	0.6	-1.0	0.5	0.2	-0.5	0.1
Cholesterol lowering medication	1.2	1.8	6.6	-0.1	0.6	-2.6	-1.7	0.9	1.1	0.0	-0.4	-2.0
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	3.2	0.7	0.4	-0.5	-1.3	-1.8	0.6	0.9	-1.2	-1.6
Pain experienced in last month	0.8	1.3	4.8	-2.2	-0.0	0.7	-0.8	-0.4	-1.0	-0.6	1.9	-0.3
Supplements: Calcium	0.2	0.3	0.9	-0.1	-0.9	0.1	-0.5	-0.4	0.9	0.5	-0.0	0.3
Basal cell carcinoma (self-reported)	0.7	0.8	2.8	-0.3	0.2	-0.2	-0.6	-0.7	1.7	1.5	-1.0	-0.8
Heart attack/myocardial infarction (self-reported)	0.7	0.9	5.9	-0.5	-0.2	-2.4	-0.3	0.2	1.3	-0.3	0.1	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	1.5	-0.7	0.5	1.1	0.5	-1.2	-0.9	1.2	1.1	0.7
Heart disease (siblings)	1.0	1.2	4.1	-0.1	-1.4	-0.9	0.4	2.0	-0.8	1.2	1.2	0.6
Alcohol drinker status: Previous	0.9	1.1	8.2	-0.1	0.3	-0.2	-0.1	-0.0	2.9	1.0	-0.4	-0.3
Pack years of smoking	0.8	1.2	5.5	-1.1	-2.3	-0.4	-0.5	1.7	-0.6	-0.2	0.4	0.2
Impedance of whole body	0.4	1.9	8.2	-0.6	-0.3	-2.9	-0.8	1.1	1.6	-1.5	0.2	-1.2
Leg fat mass (left)	0.1	0.4	1.4	1.2	-0.2	0.6	0.9	0.3	-0.6	0.2	0.1	0.3
Arm predicted mass (left)	0.2	0.9	3.7	-0.1	-0.9	1.9	-0.0	-0.4	-1.4	-0.5	1.2	0.6