Hub : Genes

KANK1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0790	0.0290	3.9e-03	0.001	0.005	0.002	0.012	0.001	2.0e-01	7.8e-02	1.7e-01	0.0100	0.22000
2	GTEx	Esophagus Mucosa	0.2210	0.0680	9.5e-05	0.065	NA	0.062	NA	0.050	3.9e-05	NA	5.5e-05	NA	0.00028
3	GTEx	Nerve Tibial	0.1411	0.0519	3.6e-03	0.038	NA	0.022	NA	0.024	1.0e-03	NA	9.5e-03	NA	0.00730
4	GTEx	Testis	0.2620	0.0750	3.0e-04	0.034	NA	0.013	NA	0.041	1.2e-02	NA	8.5e-02	NA	0.00620
5	NTR	Blood	0.0349	0.0126	3.4e-03	0.000	0.004	0.007	0.007	0.004	4.0e-01	2.0e-02	1.7e-03	0.0014	0.01900
6	TCGA	Head and Neck Squamous Cell Carcinoma	0.0648	0.0236	1.8e-04	0.018	0.047	0.024	NA	0.022	3.9e-03	5.5e-06	8.6e-04	NA	0.00140
7	TCGA	Lung Adenocarcinoma	0.1396	0.0471	2.2e-04	-0.002	0.027	0.002	NA	-0.001	6.6e-01	3.5e-04	1.6e-01	NA	0.50000
8	TCGA	Lung Squamous Cell Carcinoma	0.0986	0.0397	4.7e-05	0.002	0.035	0.010	NA	0.015	1.7e-01	6.5e-05	2.1e-02	NA	0.00680
9	TCGA	Testicular Germ Cell Tumors	0.2030	0.0750	2.4e-04	0.024	0.078	0.043	NA	0.051	4.7e-02	1.1e-03	1.2e-02	NA	0.00710
10	TCGA	Thyroid Carcinoma	0.0750	0.0370	2.8e-03	-0.002	0.014	0.001	NA	-0.002	7.2e-01	1.4e-02	2.2e-01	NA	0.55000

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	0.9	1.4	4.3	2.1	-0.8	1.6	0.6	1.1	-0.6	-1.3	-0.2	0.6	1.5
Bipolar Disorder or Schizophrenia	0.4	1.0	2.9	0.6	-1.1	1.6	0.9	0.6	0.4	-1.7	-1.2	0.8	-0.1
Depressed Affect (Nagel 2018)	1.7	3.6	18.9	-0.8	0.9	-4.3	-1.6	-0.7	1.8	1.8	1.9	0.4	-1.6
Depression (Nagel 2018)	1.0	1.5	6.2	0.2	0.9	-2.5	-0.6	0.9	0.2	-0.8	2.1	1.2	-0.2
Intelligence (Savage-Jansen 2018)	0.4	1.3	3.3	-0.9	1.5	-1.4	-1.4	-1.1	-0.3	0.2	0.8	-1.8	-0.6
Neuroticism (Nagel 2018)	0.7	1.6	10.1	-0.1	1.1	-3.2	-0.6	-0.8	0.7	0.2	1.3	0.0	-1.0
Schizophrenia (2018)	0.4	0.9	2.0	-0.9	-0.9	0.7	0.6	-0.1	1.0	-1.1	-1.4	0.6	-1.2
Schizophrenia vs Biploar Disorder	0.6	0.8	2.7	-1.6	1.5	-0.5	-0.9	-0.6	0.8	-0.0	0.3	0.1	-1.2
Worry (Nagel 2018)	0.5	1.0	5.8	-0.8	1.4	-2.4	-0.4	-0.9	-0.0	-0.2	0.9	-0.1	0.3
Alzheimer’s Disease (in mother)	0.5	0.5	1.8	0.6	-0.1	-1.0	-0.3	0.7	-0.8	-1.4	0.5	-0.9	-0.2
Alzheimer’s Disease (in father)	1.4	1.5	5.2	-0.6	0.2	-1.0	-1.0	0.4	2.3	1.1	2.1	1.1	0.7
Alzheimer’s Disease (including proxy)	0.4	0.6	1.7	-0.2	0.7	-1.3	-0.9	0.3	0.1	0.1	1.3	-0.5	0.8
Crohns Disease (2017)	0.8	1.8	6.2	-2.5	2.0	0.5	-1.4	-0.3	-0.5	-0.5	0.9	-1.4	1.5
Irritable Bowel Disease (IBD)	0.3	0.8	2.9	-0.8	0.2	1.2	0.9	0.6	-0.8	-1.7	-0.6	-1.0	0.3
Ulcerative Colitis (UC)	1.0	1.9	5.3	1.5	-0.9	1.5	2.3	0.9	-0.6	-2.1	-1.6	-0.6	-0.4
Major Depression (MDD)	0.4	0.5	1.7	-1.3	0.8	0.3	0.3	0.9	-0.9	-0.9	0.0	0.1	0.0
Reaction Time	1.0	1.8	5.1	1.9	-1.0	-1.2	2.3	0.9	-1.0	-0.8	-1.0	1.0	-1.7
Verbal and Numeric Reasoning (VNR)	0.5	1.3	5.8	0.1	1.0	-0.8	0.1	-1.1	-1.5	-1.1	-0.8	-2.4	-0.3
Breast Cancer	0.4	0.9	2.8	1.2	-0.9	0.1	1.7	-0.9	-1.2	0.4	-1.0	-0.3	0.6
Ovarian Cancer	1.1	1.5	5.8	0.9	0.2	0.5	2.4	0.3	-1.8	-1.4	-1.5	-0.2	0.2
Prostate Cancer	1.3	1.8	6.4	-1.9	-2.5	1.4	0.0	-0.4	-0.1	0.8	-2.1	-0.2	-0.7
Age at First Birth	1.0	1.4	5.7	1.3	1.7	0.6	-0.4	2.4	1.1	-0.3	0.3	0.1	1.3
Bipolar Disorder (2011)	0.5	0.5	2.6	0.1	-0.0	1.6	-0.1	1.3	0.7	0.1	-0.1	0.5	0.1
Body Mass Index (BMI) (2010)	0.6	0.8	2.6	-0.6	0.3	-1.2	-1.6	0.7	1.2	0.2	1.2	0.6	-0.3
Coronary Artery Disease (CAD)	0.6	0.7	1.8	-1.2	1.0	-1.4	-1.2	-0.5	0.1	0.3	1.0	0.4	0.2
Crohns Disease (2012)	1.3	2.2	12.4	-1.4	3.5	-0.6	-1.0	-0.2	-0.3	0.8	0.9	-0.6	2.0
Mean Putamen Volume	1.3	1.5	10.8	0.6	-0.9	-0.8	-0.7	-0.7	1.1	-0.3	-0.2	0.4	-3.3
Fasting Glucose	1.0	1.2	6.3	0.8	-0.1	-2.5	-0.6	0.3	0.9	1.4	-0.1	0.3	-1.2
HbA1C	0.6	0.7	3.8	0.5	-0.6	0.1	-2.0	-0.1	1.4	0.3	0.2	0.6	-0.1
HDL Cholesterol	0.3	0.5	1.7	-0.9	-0.3	0.3	-0.4	-1.3	-1.1	-0.1	0.2	-1.0	-0.1
LDL Cholesterol	0.4	0.7	2.8	0.4	0.3	0.9	-1.7	-0.4	0.3	0.4	1.0	-1.1	0.2
Lupus	1.8	2.8	5.8	1.3	-1.0	0.9	1.6	1.1	-2.3	-2.0	-2.4	-2.4	-0.2
Neuroticism (2016)	1.2	1.8	9.5	-0.8	-0.3	-3.1	0.0	-0.9	0.7	2.2	0.3	0.1	-1.1
Primary Biliary Cirrhosis	0.4	0.6	1.4	0.3	-0.3	0.2	-0.3	1.2	1.0	-0.9	1.2	0.6	-0.8
Rheumatoid Arthritis	1.8	2.5	5.8	-1.4	0.7	-0.1	-1.5	2.3	2.2	-0.9	2.4	1.3	1.4
Schizophrenia (2014)	0.3	0.7	3.7	-0.5	-0.1	0.4	0.2	-0.0	1.1	-1.9	-0.5	0.3	-1.2
Triglycerides	0.5	0.8	2.4	0.4	0.2	0.6	-1.4	0.2	1.1	0.1	1.6	1.3	0.3
Type 2 Diabetes (T2D) (2012)	1.1	1.2	4.0	-1.5	-0.4	1.0	-0.5	2.0	-0.2	-0.7	1.5	-1.2	0.6
Ulcerative Colitis	0.7	1.0	3.5	0.9	-1.3	0.1	1.9	0.7	-0.1	-1.0	-1.5	0.2	-0.7
Blood Eosinophil Count	0.1	0.5	1.3	0.2	0.1	0.3	1.1	1.1	-0.4	-1.1	0.2	1.0	-0.0
Blood Platelet Count	0.4	4.9	24.7	4.1	-0.1	-5.0	0.9	-0.5	2.0	0.7	-0.4	1.3	0.2
Blood Red Count	0.2	1.6	7.5	-2.7	0.3	-0.3	-0.8	-0.6	-1.5	-0.7	0.9	-0.3	1.9
Blood White Count	0.7	5.0	15.2	0.6	0.4	3.9	-0.5	2.7	3.3	0.3	1.7	2.3	2.8
Heel T-Score	1.2	9.4	21.9	-0.2	3.4	-4.4	-1.7	1.2	4.0	4.7	3.6	2.0	2.1
BMI	0.4	2.3	8.5	2.8	-0.5	0.3	2.9	1.9	-1.1	0.3	-1.1	0.1	0.2
Height	0.6	11.2	31.1	1.7	-2.4	0.4	1.8	-1.3	-2.7	-3.6	-5.0	-5.6	-4.7
Waist Hip Ratio (WHR)	0.5	2.2	8.0	1.3	0.0	1.7	0.9	2.8	-0.4	-1.4	1.2	1.9	1.3
Systolic Blood Pressure	0.6	2.9	20.6	-0.4	0.9	1.0	-0.9	0.4	0.3	-0.4	1.2	1.9	4.5
Smoking Status	0.3	0.6	3.6	-0.4	0.6	-0.6	0.1	1.9	-0.2	0.9	0.1	0.5	0.7
Allergy or Eczema	1.2	3.0	8.5	-2.9	2.5	0.9	-2.4	1.1	-0.3	-1.0	1.6	-2.0	-0.2
Cardiovascular Disease	0.8	2.5	8.7	2.2	0.3	1.9	0.4	2.4	0.1	-1.2	-0.8	0.0	3.0
Hypothyroidism (self reported)	0.4	0.8	2.7	-1.4	0.7	1.6	0.4	0.6	-0.3	-1.1	0.4	-0.8	0.7
Respiratory disease	0.6	1.2	5.0	-2.2	1.4	1.2	-0.1	-0.1	0.4	-0.2	1.5	0.9	0.8
Type 2 Diabetes (T2D) (2018)	1.3	2.4	6.5	1.1	-2.4	1.2	2.4	0.5	-0.9	-1.3	-2.5	0.5	-1.0
Lung FEV1/FVC ratio	1.9	9.7	19.2	3.6	-1.1	4.4	2.9	1.7	-3.9	-2.4	-3.7	-4.1	0.3
Lung FVC	0.1	0.5	2.4	-0.2	1.0	0.5	-0.6	-0.6	-0.1	-0.4	0.0	0.7	1.6
Neuroticism	0.7	1.6	10.0	-1.0	0.2	-3.2	-0.6	-0.0	1.4	0.5	1.2	1.0	-0.5
Chronotype (morning person)	0.4	1.0	2.8	0.0	-0.6	1.7	0.8	1.1	-0.7	-0.9	-1.6	-0.7	-0.8
Hair Pigment	0.2	5.5	21.9	-4.7	0.1	2.9	0.4	-1.7	-3.1	-0.2	-0.5	-1.8	2.9
Tanning	0.1	0.7	2.8	-0.0	1.4	1.7	-0.1	-0.5	-0.5	-1.0	0.7	-0.5	-0.2
Hand grip strength (left)	0.5	1.2	3.5	1.5	0.5	1.9	1.1	0.3	-0.4	-1.7	-0.3	-0.8	1.0
Number of treatments/medications taken	0.8	1.4	3.7	0.2	1.9	0.5	-0.2	1.0	1.0	-1.8	1.4	0.6	1.6
Average weekly spirits intake	0.6	0.8	4.1	-0.9	-2.0	1.1	-0.1	0.7	0.5	-0.6	0.2	0.7	0.2
Sensitivity / hurt feelings	0.4	0.8	2.2	-0.5	0.5	-1.5	-1.1	-0.9	-0.1	1.5	0.5	-0.6	0.3
Frequency of depressed mood in last 2 weeks	1.2	1.6	4.5	-1.0	0.6	-2.1	-1.5	-1.5	-0.3	0.4	2.0	1.2	-0.3
Hearing difficulty/problems: Yes	2.0	3.1	9.9	-2.0	0.5	1.4	0.3	-2.0	-2.9	-1.1	-0.8	-3.1	0.9
Relative age of first facial hair	1.4	2.8	11.4	-1.2	0.5	-0.6	0.6	-2.1	-3.4	1.5	-1.1	-2.3	0.7
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.3	-0.2	0.6	-0.1	0.3	1.2	0.5	0.5	0.4	0.4	0.5
Ever used hormone-replacement therapy (HRT)	1.7	2.2	5.4	2.3	-2.1	0.5	1.7	1.2	-0.7	-1.6	-1.7	0.7	-1.2
Ever had hysterectomy (womb removed)	0.9	1.0	2.8	-1.2	-0.7	0.3	-0.6	-1.1	-1.7	0.6	-1.0	-1.5	-0.4
Systolic blood pressure, automated reading	0.7	2.2	10.2	0.7	-0.2	1.7	0.2	0.6	1.0	0.2	0.8	2.5	3.2
Eye problems/disorders: Diabetes related eye disease	1.7	1.9	7.3	-0.3	-1.8	-2.7	-0.0	-1.6	-0.7	2.0	-1.0	-0.5	-0.3
Angina	1.9	2.5	10.3	-1.2	-0.7	0.8	-1.7	0.2	3.2	1.7	2.1	1.4	0.5
Medication for hormone replacement therapy	0.6	0.7	2.2	0.7	-0.8	-1.5	0.1	0.6	0.8	0.3	0.3	1.5	-0.7
Vitamin and mineral supplements	0.3	0.4	1.3	-0.2	-1.0	-0.1	0.0	-0.3	-1.2	-0.3	-0.8	-1.0	0.0
Supplements: Zinc	2.5	2.7	9.4	-0.0	3.1	-2.4	-2.0	-0.1	1.7	1.0	2.0	0.2	0.3
Medication: Co-codamol	1.0	1.1	5.2	-0.6	-0.3	1.7	0.0	-0.7	-0.1	-2.3	-0.6	-0.8	-1.1
Medication: Metformin	1.4	1.9	7.1	1.2	-0.9	0.6	1.8	-0.3	-1.8	-0.5	-2.7	-1.6	-0.4
Diabetes (father)	1.1	1.3	6.9	-2.6	-0.5	-0.7	-0.5	-1.5	-0.1	0.8	0.1	-0.2	-1.5
Diabetes (mother)	0.3	0.4	1.3	-0.6	0.2	0.5	-0.3	0.2	-0.6	0.6	-0.6	-1.1	-1.1
Severe depression (siblings)	0.3	0.3	1.0	-0.0	-0.9	0.5	-0.5	0.2	1.0	-0.3	-0.0	0.0	-0.6
Pack years adult smoking proportion	1.4	2.2	9.6	2.1	-1.4	-0.6	3.1	-0.6	-0.2	-1.0	-1.1	1.6	0.1
Impedance of leg (right)	0.3	1.4	5.6	-0.4	-0.0	1.0	1.3	-0.2	-1.6	-2.4	-1.1	-1.4	-0.2
Leg fat-free mass (left)	0.2	0.9	2.4	1.6	-0.2	-0.5	1.4	0.8	0.2	0.6	-1.5	-0.3	-0.8
Trunk fat percentage	0.3	1.4	6.8	2.1	0.5	-0.1	2.6	1.2	0.0	-0.4	-0.5	0.3	-0.2
Hand grip strength (right)	0.6	1.7	4.0	1.6	1.0	1.6	1.0	0.0	-1.4	-1.5	-0.7	-1.3	2.0
Townsend deprivation index at recruitment	1.2	1.7	5.3	0.8	-0.6	1.1	1.5	2.3	-0.3	-0.7	-0.7	2.0	1.5
Current tobacco smoking	0.3	0.5	2.4	-0.3	0.8	-0.5	-0.3	1.0	-0.4	0.3	0.4	0.1	1.5
Average weekly fortified wine intake	0.7	0.8	4.1	-0.7	-1.0	2.0	0.5	1.2	0.1	-0.7	-0.4	-0.0	-0.7
Maternal smoking around birth	0.6	0.8	3.2	0.0	-0.7	1.0	0.8	-0.1	0.7	-1.8	-1.2	-0.4	-0.9
Fed-up feelings	2.2	4.0	14.1	-1.8	0.4	-3.8	-1.2	-0.2	1.7	2.3	1.6	1.3	-3.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	3.0	0.5	0.8	-1.5	-0.2	0.4	-0.0	0.2	1.7	1.6	-0.9
Relative age voice broke	0.7	1.1	4.4	-2.1	0.5	-1.2	-0.3	-0.2	-1.6	0.1	0.8	-0.2	1.3
Taking other prescription medications	0.5	0.7	2.9	-1.7	0.7	-0.8	0.0	-1.1	-0.3	-0.9	-0.4	-0.9	-0.6
Age when periods started (menarche)	0.3	0.8	3.4	0.2	-1.1	0.4	1.8	-0.0	-0.2	-1.5	-0.4	0.4	0.2
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	3.0	-1.1	-0.7	0.6	-0.4	-1.7	-0.9	0.9	-0.7	-0.2	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	3.9	-0.6	1.5	-1.8	-0.3	0.8	2.0	1.6	0.2	0.4	0.2
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.5	0.6	-0.4	-0.8	0.6	-0.8	-1.1	1.1	-0.1	-1.0	1.2
Qualifications: CSEs or equivalent	1.1	1.4	4.7	-1.6	0.4	0.8	-0.2	-0.4	-1.4	0.7	-0.7	-2.2	-1.6
Serious illness, injury or assault to yourself	0.7	0.8	2.3	-1.4	-0.1	1.5	-0.4	0.5	1.1	0.3	-0.3	-1.1	-0.8
High blood pressure	1.5	4.2	26.5	1.6	2.1	0.6	-0.1	2.0	1.0	1.1	0.9	1.2	5.1
Hayfever, allergic rhinitis or eczema	1.5	3.3	14.8	-3.8	1.9	0.8	-2.8	0.9	0.3	-0.9	2.0	-1.1	-0.2
Multivitamins +/- minerals	0.3	0.3	1.0	0.1	0.6	-0.1	-0.6	-0.3	1.0	-0.2	1.0	0.6	-0.5
Stomach or abdominal pain in last month	1.2	1.5	3.6	1.4	0.0	-0.9	1.3	0.8	-1.9	-1.3	-0.8	-1.8	0.7
Supplements: Glucosamine	1.0	1.4	4.3	0.8	1.8	-2.1	-0.3	-0.6	0.4	-1.5	0.0	-0.6	-1.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.5	-1.2	0.7	-0.2	-1.0	-0.5	-0.4	0.4	-0.4	-0.5	-1.1
Medication: Atenolol	2.4	3.0	6.1	2.3	-1.2	2.2	0.9	2.1	2.5	1.3	-1.2	1.6	1.4
Medication: Levothyroxine sodium	0.4	0.7	2.6	-1.6	1.1	-0.3	0.2	-1.0	0.3	0.0	1.3	0.1	0.8
Sitting height	0.4	2.6	7.9	1.9	-1.0	1.1	0.7	0.3	-0.8	-2.3	-2.8	-2.2	-1.0
Chronic bronchitis/emphysema (father)	0.8	1.0	3.1	1.7	0.8	-1.8	0.3	0.2	-0.6	1.3	0.3	-0.2	1.0
High blood pressure (mother)	1.8	2.5	11.1	0.1	1.6	-0.5	-1.4	-0.6	1.8	3.3	0.9	1.8	1.3
Body mass index (BMI)	0.3	1.1	4.3	1.6	0.3	-0.4	2.1	0.9	0.3	1.2	-0.4	1.0	0.2
Impedance of leg (left)	0.3	1.3	6.9	0.3	0.5	0.6	0.9	0.2	-1.5	-2.6	-0.6	-1.5	-0.1
Leg predicted mass (left)	0.2	0.9	2.6	1.6	-0.3	-0.5	1.4	0.8	0.2	0.7	-1.5	-0.2	-0.8
Trunk fat mass	0.4	1.7	7.7	2.4	0.3	-0.3	2.8	1.4	-0.1	-0.4	-1.2	0.2	-0.3
Waist circumference	0.3	1.1	2.4	1.5	0.3	-0.1	1.2	1.6	0.7	0.9	0.5	1.5	-0.0
Number of incorrect matches in round	0.4	0.6	2.2	0.6	-0.6	0.3	0.7	0.5	-1.1	-1.5	-0.0	-0.3	-1.0
Past tobacco smoking	0.4	0.7	4.5	0.3	-0.7	-0.2	-0.8	-2.1	1.0	-0.0	0.1	-0.2	-0.2
Alcohol usually taken with meals	1.6	2.5	10.1	-2.1	-3.2	2.0	-0.2	-0.1	-0.0	-1.6	-0.2	0.4	-2.0
Nervous feelings	0.8	1.5	6.7	0.0	1.3	-2.6	-0.6	-1.5	-0.5	1.5	0.8	-0.2	0.8
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.5	5.2	-2.3	1.1	-1.0	-1.2	-1.6	-1.1	1.3	0.9	0.4	0.5
Hearing difficulty/problems with background noise	1.5	2.5	5.6	-1.1	-1.8	1.9	1.7	1.0	-2.3	-2.4	-0.7	-0.6	-0.6
Hair/balding pattern: Pattern 2	0.9	1.2	4.2	0.0	0.2	-1.8	0.0	-0.8	-0.5	1.4	0.2	1.1	2.1
Had menopause	3.1	3.8	13.6	0.9	-0.3	1.3	0.8	-1.2	-3.3	-1.5	-2.5	-3.7	-0.6
Had other major operations	0.8	0.9	4.6	0.7	0.5	0.9	0.9	0.9	0.1	2.1	-1.0	0.1	-0.5
Forced vital capacity (FVC)	0.3	1.0	3.7	0.7	-0.9	1.1	0.9	0.2	0.1	-1.9	-1.6	0.7	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	6.2	-0.6	2.4	-1.9	-0.3	0.3	2.3	2.5	0.1	0.9	0.8
Ever unenthusiastic/disinterested for a whole week	1.7	2.1	7.7	0.7	1.6	-2.8	-0.6	-0.1	-0.5	1.7	0.9	-0.4	2.4
Qualifications: None of the above	0.6	1.3	6.8	0.2	0.4	-1.2	2.6	0.8	0.9	0.2	-0.6	1.5	0.3
Financial difficulties in last 2 years	1.8	2.4	6.2	-0.9	2.2	-2.2	-1.6	-0.4	0.6	0.9	1.8	0.5	2.5
Mouth/teeth dental problems	1.9	2.9	7.9	-0.8	0.9	-2.1	-2.1	-1.8	-2.4	-0.6	0.1	-2.8	-1.0
Heart attack	1.3	1.7	4.4	-0.3	0.8	-1.0	-2.1	-1.2	1.2	1.4	1.7	1.2	1.2
Allergy	1.3	3.1	15.8	4.0	-2.1	-1.1	2.1	0.1	-0.4	0.9	-1.9	0.8	0.4
Pain all over the body in last month	0.8	0.8	3.9	-0.3	-0.1	-1.1	-0.2	0.5	0.9	2.0	0.3	0.9	1.0
Diabetes (self-reported)	1.1	1.6	4.6	1.3	-1.2	1.2	2.1	1.4	-0.5	-1.0	-1.7	0.8	0.8
Hayfever/allergic rhinitis (self-reported)	1.9	2.5	10.6	-3.2	0.9	1.2	-2.6	-0.8	1.4	1.4	0.8	-0.1	-0.3
Medication: Ramipril	1.4	1.7	4.9	0.3	1.2	-0.1	-2.0	0.7	1.2	1.6	1.3	0.9	2.2
Medication: Simvastatin	0.8	1.1	6.0	0.4	-0.7	0.8	-0.8	1.3	2.5	-0.6	0.1	0.8	0.8
Fluid intelligence score	0.2	0.3	0.8	-0.5	0.7	-0.6	0.2	-0.5	-0.9	-0.8	-0.4	-0.7	-0.2
Illnesses of siblings	0.3	0.5	1.1	0.1	-1.0	0.1	1.0	-1.0	-0.6	-0.4	-0.7	0.5	-0.2
Neuroticism score	1.2	2.5	14.4	-1.3	0.3	-3.8	-0.8	-0.6	1.1	1.1	1.7	1.5	-0.9
Weight	0.3	1.5	5.6	2.0	-0.3	-0.2	2.4	1.1	-0.3	0.1	-1.7	-0.3	-0.7
Impedance of arm (right)	0.1	0.6	2.1	-1.4	-0.3	0.5	-0.7	0.3	0.9	-0.5	1.1	0.8	-0.3
Arm fat percentage (right)	0.3	1.2	4.4	1.5	-0.1	-0.6	2.1	1.3	0.7	0.8	-0.2	1.4	0.0
Trunk fat-free mass	0.3	1.5	6.5	1.5	-1.0	-0.4	1.5	0.6	-0.7	-0.3	-2.5	-0.9	-1.0
Hip circumference	0.2	0.8	2.0	1.3	-0.8	-0.7	0.9	-0.0	0.6	0.9	-0.8	0.6	-1.4
Time employed in main current job	0.9	1.0	5.7	0.3	-0.3	-0.6	0.3	-2.4	-1.3	-0.8	-1.0	-0.7	0.3
Alcohol intake versus 10 years previously	0.6	0.9	2.8	-1.7	1.7	-0.7	-1.0	-0.3	0.8	0.1	0.5	-0.8	0.1
Father’s age at death	0.9	1.1	3.6	-1.0	-0.9	1.3	0.4	-0.7	-0.7	-0.8	-1.9	-1.6	0.1
Worrier / anxious feelings	0.2	0.4	1.4	0.1	-0.7	-0.8	-0.0	-0.6	0.2	0.1	0.7	1.2	-0.8
Frequency of tiredness / lethargy in last 2 weeks	2.4	3.8	8.6	-2.0	0.4	-2.9	-1.4	-1.4	2.7	2.7	2.0	1.7	-0.3
Falls in the last year	1.5	2.0	4.4	-2.1	1.0	-2.0	-0.8	-0.9	1.9	0.9	1.7	1.3	0.0
Hair/balding pattern: Pattern 3	0.2	0.3	0.6	0.8	0.4	0.8	0.3	0.7	0.6	0.3	-0.6	0.3	-0.0
Number of live births	0.7	0.9	3.7	-1.9	0.2	0.1	0.5	-1.4	-0.8	1.0	0.3	0.9	-0.7
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	3.8	1.1	-1.0	1.7	1.1	0.4	-0.6	-1.8	-1.9	-0.3	-0.4
Pulse rate	0.2	0.3	1.1	-0.2	-0.7	-0.8	1.1	-0.2	0.3	0.1	-0.8	0.2	-0.1
Happiness	0.6	0.8	2.8	0.2	-1.7	-0.3	1.2	-0.4	-0.6	0.2	0.0	1.5	-0.9
Noisy workplace	0.4	0.5	1.1	-0.8	0.9	0.2	0.3	0.1	-1.0	-0.0	-1.0	-0.8	0.8
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.7	-0.4	-0.4	1.6	-0.3	-0.3	1.6	0.6	0.3	0.8	0.1
Serious illness, injury or assault of a close relative in last 2 years	1.9	2.2	7.0	1.5	1.0	0.1	1.2	-0.8	-2.6	-1.3	-1.0	-2.6	-0.5
Mouth/teeth dental problems: Dentures	1.9	3.1	5.5	1.5	-2.3	2.0	1.5	1.9	2.1	0.2	-1.3	2.3	-1.4
Asthma	0.6	1.1	6.3	-2.5	1.3	0.5	-0.1	-1.2	-0.7	0.0	1.0	-0.1	0.5
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	5.6	-0.5	-0.1	-1.3	1.1	1.7	-0.4	-2.4	0.5	0.6	0.7
Medication: Cholesterol lowering	2.1	3.3	9.9	0.3	0.6	0.0	-2.6	1.5	3.1	1.0	2.1	2.0	2.1
Depression (self-reported)	0.4	0.5	1.8	0.6	-0.6	-1.3	0.6	-0.8	-0.5	-0.3	0.4	-0.3	-1.0
Medication: Lansoprazole	0.8	0.9	3.9	-0.0	-0.7	0.1	0.0	-1.0	0.0	-0.2	-1.3	-2.0	-1.5
Prospective memory result	0.9	1.1	3.3	-1.2	0.0	0.1	-1.5	0.9	1.8	0.1	1.0	0.4	-1.6
Lung cancer (father)	1.3	1.5	7.0	1.1	2.6	-1.8	-0.9	-0.4	0.5	0.8	0.4	-0.9	1.0
Illnesses of mother	0.7	0.9	4.1	0.3	0.3	-0.1	1.4	0.6	-1.1	-2.0	0.2	-0.8	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	5.5	2.4	-0.8	1.8	1.9	0.8	-1.4	-1.5	-2.3	-0.5	0.4
Pulse wave Arterial Stiffness index	0.9	1.0	3.6	1.9	-0.7	0.8	0.9	1.3	-0.3	-1.3	-0.4	-0.5	-0.9
Impedance of arm (left)	0.1	0.7	2.2	-1.3	0.0	0.5	-1.0	-0.1	0.9	-0.5	1.5	0.5	-0.6
Arm fat mass (right)	0.3	1.2	6.1	1.6	-0.2	-0.2	2.5	1.0	0.0	0.3	-1.0	0.6	-0.5
Trunk predicted mass	0.2	1.4	6.1	1.5	-1.0	-0.5	1.4	0.6	-0.7	-0.3	-2.5	-0.8	-0.9
Standing height	0.4	3.9	10.2	1.1	-1.4	0.6	1.1	0.7	-1.2	-2.7	-3.2	-2.9	-2.5
Length of working week for main job	0.9	1.0	2.8	1.7	-0.8	-1.3	0.8	-1.0	-0.7	0.3	-1.1	0.2	-1.2
Exposure to tobacco smoke at home	1.4	1.5	4.8	1.1	1.4	-1.4	0.2	-0.9	-2.2	1.2	-1.6	-0.7	-0.0
Breastfed as a baby	0.7	0.9	3.2	-0.5	-0.8	1.4	0.2	-0.9	-0.4	-1.8	-0.1	0.1	-1.3
Tense / ‘highly strung’	0.3	0.4	1.9	0.7	0.3	-1.4	0.8	0.4	-0.7	-0.2	-0.2	0.7	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	6.9	0.8	0.0	-2.6	0.3	-0.3	-1.2	-0.9	0.2	-0.8	-0.5
Hair/balding pattern: Pattern 4	0.8	1.9	8.5	0.8	-0.4	-0.4	0.2	-0.5	-1.0	0.3	-2.0	-2.9	-2.1
Birth weight of first child	1.0	1.9	8.1	-2.8	1.1	-0.5	-1.3	-1.3	0.1	-0.6	0.7	-1.3	-1.9
Peak expiratory flow (PEF)	0.7	1.6	4.9	2.1	-1.4	0.7	1.3	-0.2	-0.6	-1.1	-2.2	-0.1	-0.9
Pulse wave reflection index	0.5	0.6	2.3	0.4	1.5	0.2	-0.5	0.8	-0.2	-1.0	1.3	-0.4	0.3
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.1	-0.2	0.0	-1.4	-0.4	0.6	0.9	0.9	0.2	0.5	0.2
Loud music exposure frequency	0.4	0.4	1.3	-0.1	-0.9	0.9	-0.5	-0.3	0.3	1.1	-0.2	0.9	0.3
Qualifications: O levels/GCSEs or equivalent	1.0	1.5	5.3	-0.7	1.4	-0.4	-1.2	-1.6	-0.4	1.1	-0.9	-2.3	1.1
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	4.4	-0.1	-0.1	1.6	1.9	1.2	0.4	0.0	-0.1	1.4	2.1
Blood clot in the leg (DVT)	1.7	2.2	4.7	0.3	-1.6	2.2	1.3	-0.3	1.4	-2.0	0.7	1.9	-1.5
Medication: Paracetamol	0.2	0.3	0.8	-0.9	-0.3	0.3	-0.0	-0.6	-0.0	-0.5	-0.1	0.7	-0.7
Headache pain in last month	0.3	0.4	0.8	-0.4	0.8	-0.9	0.9	-0.0	-0.8	-0.4	-0.7	-0.3	-0.9
Medication for cholesterol, blood pressure or diabetes	2.1	3.6	10.0	-0.4	-0.7	0.3	3.1	-1.3	-3.2	-1.4	-2.3	-1.6	-2.0
Glaucoma (self-reported)	0.8	0.9	4.4	0.5	0.3	-2.1	0.5	-1.8	-0.4	0.3	-0.4	-0.1	-0.7
Gout (self-reported)	1.9	2.6	5.9	1.4	-1.8	1.6	2.4	1.5	-0.7	-1.4	-2.2	-1.1	-1.2
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.8	-1.1	0.9	0.9	0.6	0.8	-0.2	-1.7	1.0	-0.6	1.0
Medication: Amlodipine	0.5	0.7	3.5	0.4	-0.6	0.8	0.6	0.8	1.9	-0.4	0.7	1.0	-0.0
Medication: Ventolin 100micrograms inhaler	2.2	2.8	7.4	-2.7	0.7	-0.5	-2.6	-1.2	1.4	1.6	2.6	-0.1	-0.8
Birth weight	0.7	1.4	3.6	0.4	-0.1	1.4	1.9	0.7	-1.8	-1.0	-1.3	-1.4	0.2
Chronic bronchitis/emphysema (mother)	1.0	1.2	3.4	-1.3	-1.1	-1.1	-0.1	-0.3	0.4	1.1	-1.2	1.1	-1.9
High blood pressure (siblings)	2.0	2.9	9.2	-1.6	1.3	-0.9	-3.0	0.7	1.6	1.9	2.1	1.1	1.7
Forced vital capacity (FVC), Best measure	0.3	1.0	3.1	1.8	-0.4	0.6	1.1	0.0	-0.5	-1.5	-1.6	0.3	0.2
Body fat percentage	0.4	1.6	8.0	2.3	0.6	-0.5	2.8	1.3	-0.3	-0.2	-0.6	0.4	0.2
Leg fat percentage (right)	0.6	2.2	11.7	2.3	0.3	-0.5	3.4	1.2	-0.9	0.4	-1.2	-0.0	0.7
Arm fat-free mass (right)	0.5	2.4	6.5	2.3	-0.1	-0.1	2.1	0.4	-1.8	-0.9	-2.6	-1.8	-0.6
Exposure to tobacco smoke outside home	0.6	0.8	4.0	0.8	2.0	0.4	0.0	0.2	-0.8	-0.0	0.2	-0.8	1.3
Comparative body size at age 10	0.5	1.3	3.4	1.8	-0.9	1.9	0.8	1.3	0.8	0.7	-0.1	1.1	-0.5
Number of full brothers	0.3	0.4	1.8	1.3	0.7	-0.8	0.3	0.7	-0.3	0.2	-0.7	0.4	0.4
Worry too long after embarrassment	0.4	0.7	2.8	-0.0	-0.4	-1.2	-0.5	-0.5	0.7	1.1	0.2	0.5	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	4.6	2.2	-0.1	-1.8	0.7	0.8	-1.0	-1.0	-1.0	-1.1	-1.4
Wheeze or whistling in the chest in last year	1.8	3.3	9.3	-2.5	2.0	-1.2	-1.7	-1.9	0.1	3.0	1.8	-0.2	1.6
Number of children fathered	0.7	0.8	1.8	-0.4	1.0	-1.3	0.2	-0.6	-1.0	-0.5	-1.2	-1.3	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.4	6.7	-0.4	1.6	-0.0	-2.6	1.5	2.0	1.2	2.4	0.5	0.6
Age at first live birth	0.4	0.6	1.9	0.5	0.1	-0.2	-1.2	0.7	1.4	0.9	-0.4	0.8	-0.8
Pulse wave peak to peak time	0.9	1.0	4.5	-2.1	0.6	-0.8	-0.8	-1.4	0.3	1.1	0.4	0.3	0.7
Health satisfaction	0.3	0.4	0.9	-0.8	0.1	-0.4	-0.3	-0.6	0.8	0.8	0.5	1.0	0.3
Shortness of breath walking on level ground	0.4	0.5	1.7	-0.6	-0.2	-1.3	-0.4	-0.5	1.2	1.1	-0.0	0.3	-0.0
Qualifications: College or University degree	0.1	0.4	2.3	0.0	-0.7	1.5	-0.3	0.1	0.4	-0.3	0.3	-0.1	-1.0
Eye problems/disorders: None of the above	1.1	1.3	3.7	1.2	1.0	1.9	0.8	1.0	-0.7	-1.7	-0.5	0.1	1.3
Mouth/teeth dental problems: Loose teeth	1.2	1.5	5.6	0.2	0.5	-0.4	0.4	1.3	2.0	1.0	1.0	2.4	1.0
Emphysema/chronic bronchitis	0.9	1.1	3.2	-1.6	0.6	-0.2	-1.5	-0.7	-0.2	0.8	1.8	-0.1	0.8
Medication for pain relief, constipation, heartburn	0.4	0.8	1.8	0.5	1.3	-0.5	-1.2	-0.9	-0.8	0.9	0.2	-1.3	-0.2
Neck or shoulder pain in last month	0.5	0.7	2.7	-0.4	0.4	-0.3	1.7	-0.3	-0.8	-1.3	-1.2	-0.6	0.1
Medication: Blood pressure	1.6	2.8	6.8	0.4	0.6	-0.6	-2.5	1.4	2.5	1.3	2.6	1.3	1.4
Angina (self-reported)	2.1	2.8	10.8	-1.4	-0.7	0.6	-2.1	-0.2	3.3	1.9	2.1	1.3	0.3
Migraine (self-reported)	0.4	0.5	2.2	-0.2	0.3	1.3	-0.0	1.5	0.5	-0.2	0.7	-0.5	-0.2
Medication: Ibuprofen	0.8	1.0	4.8	-1.0	0.7	-1.1	0.9	1.0	-0.5	-2.2	0.6	0.1	0.4
Medication: Allopurinol	2.4	3.2	8.4	0.2	-2.3	1.6	2.9	1.5	-1.2	-1.4	-2.7	-1.0	-1.2
Medication: Omeprazole	0.5	0.6	3.1	-0.3	0.1	-0.2	-0.5	-0.8	-0.1	0.4	-0.9	-1.8	-0.8
Medication: Seretide 50 evohaler	0.9	1.0	3.2	-1.1	0.8	0.2	0.1	-1.3	-1.8	1.1	-0.5	-1.2	-0.3
Mean time to correctly identify matches	0.9	1.7	5.7	2.4	-1.1	-1.6	1.7	0.9	-0.9	-0.3	-0.6	1.2	-0.9
Heart disease (mother)	1.1	1.3	4.7	1.1	-0.4	-0.4	1.6	-0.9	-0.5	0.0	-2.2	-1.7	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	2.3	1.2	1.2	0.2	0.9	1.5	1.0	1.2	0.3	0.9	1.5
Whole body fat mass	0.4	1.6	7.6	2.1	0.3	-0.5	2.8	1.2	-0.3	-0.4	-1.2	0.1	-0.3
Leg fat mass (right)	0.5	2.0	9.5	2.3	0.5	-0.4	3.1	1.1	-0.6	0.4	-1.6	-0.2	0.4
Arm predicted mass (right)	0.5	2.6	7.0	2.4	-0.4	-0.1	2.2	0.4	-1.7	-0.9	-2.6	-1.7	-1.0
Pulse rate, automated reading	0.3	1.1	2.2	1.2	0.9	-1.5	0.7	-1.2	-0.7	0.2	-1.2	-0.1	1.4
Alcohol intake frequency.	0.2	0.4	1.5	-0.0	0.3	0.4	0.7	-0.8	-1.2	1.0	-0.6	-0.0	0.4
Comparative height size at age 10	0.3	1.4	3.4	0.7	-1.8	0.1	0.7	-0.0	0.1	-1.4	-1.8	-1.2	-1.9
Number of full sisters	0.6	0.7	2.0	-0.2	0.0	0.8	1.0	1.4	0.4	1.3	-0.2	0.7	0.9
Suffer from ‘nerves’	0.4	0.7	3.7	-1.1	0.2	-1.9	-0.6	-0.6	-0.6	0.7	0.2	-0.6	0.1
Overall health rating	0.8	1.7	5.3	-0.4	1.3	-1.5	0.6	-0.5	1.3	1.2	0.7	1.9	2.3
Chest pain or discomfort	1.0	1.4	4.7	-0.4	0.8	0.0	-0.7	0.5	1.6	1.3	1.4	1.2	2.2
Had major operations	1.3	1.5	4.1	-0.8	2.0	-0.4	-1.4	0.2	1.2	-0.0	1.4	1.2	1.7
Age at last live birth	0.3	0.4	1.5	-0.9	0.3	0.0	-1.2	0.3	0.4	0.5	0.6	0.4	-0.7
Family relationship satisfaction	0.6	0.7	3.1	0.5	-1.5	-0.4	0.3	-0.2	-0.2	-0.9	0.2	1.8	-0.3
Leg pain on walking	1.5	1.8	7.2	-0.1	0.4	-2.5	-0.3	-1.5	-0.7	2.7	-1.1	-0.8	-0.4
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	5.9	0.7	1.6	-2.4	0.2	0.9	0.0	0.6	1.7	-0.0	1.7
Commuting to job workplace: Car/motor vehicle	2.1	2.4	5.1	1.0	-1.9	0.8	1.8	-1.3	-1.9	-0.6	-2.3	-1.8	-1.0
Illness, injury, bereavement, stress in last 2 years	1.6	2.0	3.3	1.8	-1.8	0.9	1.8	1.5	-0.3	-1.1	-1.4	1.2	-1.5
Medication: Aspirin	0.7	0.9	2.6	1.3	-1.4	1.6	0.8	-0.0	-0.1	-0.6	-0.9	0.5	0.9
Supplements: Vitamin C	1.6	1.8	8.2	2.9	2.0	0.5	0.5	1.4	0.4	0.7	0.2	0.1	1.8
Knee pain experienced in last month	0.5	0.8	2.2	0.6	0.8	-1.4	0.2	0.8	-1.5	-0.3	0.3	-0.4	-1.2
Hypertension (Self-reported)	1.4	4.0	24.8	1.5	1.8	1.0	-0.3	1.9	1.1	1.1	1.0	1.2	5.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.7	-0.2	-0.8	-0.2	-0.4	0.7	0.8	0.9	-1.0	-1.2	-1.6
Illnesses of father: Heart disease	0.8	1.2	4.6	0.9	0.1	1.3	-1.3	-0.1	-0.8	-1.2	-0.9	-2.2	-0.0
Illnesses of siblings: Diabetes	0.4	0.5	1.4	-0.3	0.1	0.7	0.4	1.2	0.7	-1.2	0.6	0.5	0.7
Smoking status: Previous	0.3	0.4	1.6	-0.3	-0.2	0.7	0.9	1.3	-1.0	-0.4	-0.4	0.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	1.0	1.0	-0.1	-0.5	0.3	0.4	0.3	-0.0	-0.3	0.3	-0.3
Whole body fat-free mass	0.2	1.3	4.8	1.7	-0.7	-0.5	1.5	0.6	-0.5	-0.1	-2.2	-0.8	-1.0
Leg fat-free mass (right)	0.1	0.8	3.0	1.7	-0.1	-0.9	0.9	0.8	0.2	0.5	-1.2	-0.3	-0.8
Arm fat percentage (left)	0.3	1.1	3.6	1.7	0.2	-0.6	1.9	1.0	0.6	0.9	0.1	1.3	-0.1
Average weekly red wine intake	1.1	1.7	3.2	-0.2	-1.7	1.8	0.4	-1.4	-1.5	0.2	-1.2	-1.7	-1.4
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.6	0.0	-0.3	-0.5	-0.7	-1.6	0.0	0.4	-0.5	-0.1	-0.8
Mood swings	2.1	3.8	12.7	-0.6	1.9	-3.6	-0.8	-1.1	2.3	2.7	2.0	1.7	-0.8
Loneliness, isolation	0.4	0.5	1.9	-0.9	-1.4	-0.8	0.3	0.3	-0.9	-0.2	0.7	0.3	-0.3
Long-standing illness, disability or infirmity	0.7	1.1	4.9	-0.6	0.8	-1.3	-0.2	0.6	0.1	-0.0	1.6	-0.7	2.2
Ever had bowel cancer screening	0.9	1.1	2.6	0.1	1.4	-0.0	-0.6	0.9	-0.5	-1.6	-0.1	-1.6	1.5
Diabetes diagnosed by doctor	0.6	0.9	2.6	0.6	-1.3	1.0	1.3	0.2	-1.0	-0.8	-1.6	-0.1	0.1
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	5.0	-1.5	0.4	-1.1	-2.2	-0.7	0.1	-0.5	0.7	-0.7	0.2
Friendships satisfaction	1.0	1.3	4.2	-0.9	-2.1	0.5	0.5	-0.9	-1.3	-1.4	-0.4	-0.2	-1.7
Qualifications: nursing, teaching	0.7	1.0	3.1	-0.6	1.4	1.8	-1.4	0.2	1.7	0.3	0.0	-0.4	0.3
Commuting to job workplace: Walk	1.0	1.0	3.1	0.3	1.8	-0.3	-0.7	0.5	0.8	0.0	1.4	1.5	1.2
Eye problems/disorders: Cataract	0.5	0.6	1.6	0.1	-0.9	-0.8	0.0	-1.3	-0.7	0.3	-0.7	-1.3	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.7	-0.2	0.0	-0.5	1.3	-0.3	-0.1	0.3	-0.2	0.8	1.0
Medication for cholesterol	0.7	1.0	3.2	-0.7	0.2	-1.4	-0.9	-0.7	-1.1	0.4	0.2	-1.4	-1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.7	-0.4	-0.1	0.4	-0.4	-1.3	-0.3	0.6	-0.2	-0.8	0.2
Back pain experienced in last month	1.1	1.7	5.9	1.3	-0.0	-0.6	1.0	-1.1	-2.4	-1.5	-0.5	-2.0	-0.2
Mineral and other dietary supplements	0.7	0.9	2.4	0.5	-0.8	1.2	0.4	1.3	-0.4	1.1	-0.7	0.1	1.6
Breast cancer (self-reported)	0.6	0.7	1.2	-0.6	-0.1	1.1	1.1	0.9	-0.6	-0.7	-1.0	-0.9	-1.0
Asthma (self-reported)	0.6	1.1	6.2	-2.5	1.3	0.4	-0.1	-1.0	-0.6	-0.1	1.1	-0.3	0.7
Osteoporosis (self-reported)	0.5	0.6	1.7	-0.6	1.0	-0.6	-0.8	-0.2	-1.3	0.2	0.3	-1.3	0.8
Osteoarthritis (self-reported)	0.4	0.6	1.0	-0.6	0.7	-1.0	-0.6	0.7	-0.8	0.8	0.8	-0.7	1.0
Medication: Aspirin	0.7	0.9	2.7	1.2	-1.2	1.7	0.6	0.3	0.6	-0.5	-0.5	1.1	0.9
Medication: Gliclazide	1.9	2.1	5.1	1.2	-0.2	1.5	1.2	-0.1	-2.2	-1.3	-1.7	-2.3	1.1
Illnesses of father: None of the above (group 1)	0.5	0.7	2.4	-1.0	-0.3	-0.5	-0.2	0.3	1.6	-0.1	1.0	0.9	-1.0
Smoking status: Current	0.4	0.7	2.3	-0.2	1.3	-0.5	-0.1	1.3	-0.6	-0.1	0.5	-0.2	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	5.7	2.4	-0.3	1.8	1.7	0.9	-0.1	-1.3	-1.1	1.2	1.1
Whole body water mass	0.2	1.3	5.0	1.6	-0.7	-0.5	1.6	0.5	-0.6	-0.0	-2.2	-0.8	-0.9
Leg predicted mass (right)	0.1	0.7	2.6	1.6	-0.2	-0.8	0.9	0.7	0.3	0.5	-1.1	-0.3	-0.9
Arm fat mass (left)	0.3	1.1	5.4	1.8	-0.1	-0.1	2.3	0.9	-0.0	0.4	-0.9	0.5	-0.4
Number of self-reported non-cancer illnesses	0.4	0.7	1.7	-0.9	1.3	-0.3	-1.0	-0.4	0.9	-0.2	0.8	-0.5	1.1
Average weekly champagne plus white wine intake	0.2	0.3	1.4	-0.3	-0.2	0.1	-0.1	-0.2	0.8	-1.2	0.8	0.5	0.6
Miserableness	2.1	3.6	9.7	-1.1	1.2	-3.1	-2.3	-0.2	2.1	2.2	2.9	0.9	-0.5
Guilty feelings	0.7	1.1	5.3	-2.3	0.2	-1.5	-0.3	-0.9	0.5	0.1	0.8	1.1	-0.7
Wears glasses or contact lenses	0.5	0.6	2.8	0.3	-1.7	-0.1	-0.1	-0.9	0.5	-0.2	-0.6	1.1	-0.8
Ever taken oral contraceptive pill	0.6	0.6	1.9	-0.9	0.2	-0.4	-1.0	0.1	1.4	0.7	0.3	1.0	-0.8
Hearing aid user	1.6	1.8	4.3	1.1	-0.9	1.9	1.6	0.3	-1.7	-2.1	-0.8	-1.3	0.3
Mother’s age at death	1.9	2.4	6.9	2.1	1.4	-0.2	-0.9	-2.3	0.2	2.6	-1.2	-1.6	0.7
Financial situation satisfaction	1.3	1.6	4.0	-0.5	0.6	-2.0	-1.3	1.2	0.6	1.7	1.6	1.0	1.2
Tinnitus: Yes, now most or all of the time	1.6	1.9	6.1	-0.3	2.0	0.4	-0.3	0.2	-2.2	-1.6	-0.2	-2.5	0.9
Commuting to job workplace: Public transport	0.5	0.6	1.8	-1.4	0.8	0.2	-1.1	0.3	1.0	0.0	0.8	0.3	0.8
Eye problems/disorders: Glaucoma	1.1	1.3	5.2	-0.3	0.1	-2.2	-0.2	-2.3	0.5	0.6	0.5	0.4	-1.5
Medication: Blood pressure	1.1	2.1	14.2	0.7	-0.0	1.6	0.8	0.8	0.4	1.0	-0.6	1.0	3.8
Pain type(s) experienced in last month: Hip pain	1.8	2.3	4.8	2.1	-1.6	-0.0	1.9	0.9	-1.2	-0.6	-2.2	-1.6	-1.4
Supplements: Fish oil (including cod liver oil)	0.8	1.0	6.3	-0.2	-0.1	-0.4	-0.3	-0.6	0.2	-2.5	0.9	0.5	-1.5
High cholesterol (Self-reported)	0.2	0.4	2.2	-0.2	-1.5	0.8	0.0	0.1	0.8	-0.2	-0.2	0.6	0.5
Medication: Bendroflumethiazide	0.9	1.3	6.3	0.3	-0.4	0.3	-0.4	-0.2	-0.1	2.5	-0.2	0.2	2.5
Medication: Paracetamol	0.3	0.5	2.0	-0.0	0.3	0.1	1.0	-0.0	-0.0	-1.2	-0.1	1.4	0.3
Medication: Lisinopril	1.1	1.4	4.6	0.5	0.5	0.8	1.9	1.7	0.1	-0.8	-0.9	-0.3	2.1
Medication: Atorvastatin	1.4	1.8	6.6	1.5	-1.4	2.6	0.7	0.2	-1.5	-0.7	-1.6	-0.7	0.5
Illnesses of father: High blood pressure	0.5	0.7	2.4	-1.1	-0.0	0.5	-0.1	0.0	-0.9	1.6	0.2	-0.0	1.4
Alcohol drinker status: Never	0.8	1.0	4.0	0.0	-1.1	-0.4	0.9	-1.5	-2.0	-0.1	-0.4	-0.7	-0.6
Ever smoked	0.4	0.7	5.0	-0.4	0.5	0.6	0.9	2.2	-0.4	0.2	-0.0	0.4	0.1
Basal metabolic rate	0.2	1.3	4.4	1.8	-0.5	-0.5	1.8	0.6	-0.4	0.1	-2.1	-0.7	-1.1
Leg fat percentage (left)	0.6	2.1	8.9	2.6	0.6	-0.8	3.0	1.5	-0.6	0.3	-0.7	0.2	0.7
Arm fat-free mass (left)	0.4	1.9	5.5	1.9	-0.2	-0.5	2.0	0.4	-1.5	-0.6	-2.3	-1.7	-0.5
Number of operations (self-reported)	0.3	0.5	1.7	0.4	1.3	-0.7	-0.2	0.3	0.6	1.2	0.5	0.5	-0.0
Average weekly beer plus cider intake	0.2	0.3	1.3	0.1	0.5	-0.7	0.1	-0.3	0.4	0.9	-0.4	0.3	1.1
Irritability	0.7	1.2	2.9	-1.3	-1.0	-1.7	-0.6	-0.8	1.3	-0.3	1.4	0.5	-1.1
Risk taking	0.1	0.2	0.9	-0.1	0.1	-0.4	0.1	-0.3	0.5	0.1	-0.3	1.0	-0.0
Ever had prostate specific antigen (PSA) test	0.8	0.9	3.1	-0.0	0.2	1.0	-1.7	-0.9	1.6	0.7	0.7	-0.5	0.4
Fractured/broken bones in last 5 years	0.5	0.6	1.4	-1.2	-0.6	1.2	0.9	-0.1	-0.3	-0.7	-0.5	-1.0	-0.6
Age started oral contraceptive pill	1.4	1.7	6.9	0.2	-0.4	1.8	0.3	-0.8	-0.6	-2.6	-1.3	-1.1	-1.6
Diastolic blood pressure, automated reading	1.0	3.1	15.0	-0.9	1.5	0.9	-0.0	0.2	0.8	1.3	1.7	2.5	3.9
Ever depressed for a whole week	1.0	1.3	4.2	-0.7	1.1	-2.1	-0.6	-0.1	-0.7	2.0	0.1	-0.1	1.4
Unable to work because of sickness or disability	1.1	1.4	5.3	-1.8	0.9	-0.7	-1.3	-1.1	1.0	2.3	0.4	-0.2	0.7
Commuting to job workplace: Cycle	0.6	0.7	3.6	0.5	-0.4	-0.2	0.0	0.5	0.3	1.9	0.4	-0.1	-1.7
Myopia	1.1	1.7	4.8	-0.4	-0.7	-1.9	-1.3	0.1	1.2	0.6	2.1	2.2	-0.2
Vascular/heart problems diagnosed by doctor	1.6	4.4	22.7	-1.4	-2.4	-0.1	1.0	-1.8	-1.8	-1.3	-1.7	-1.4	-4.8
Cholesterol lowering medication	1.5	2.2	4.4	-0.4	-1.5	1.9	1.4	-1.8	-1.2	-1.7	-2.1	-1.2	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.9	0.3	-0.6	-0.3	-0.3	-0.8	0.1	0.4	-0.6	-1.0	-1.4
Pain experienced in last month	1.3	2.1	6.9	-2.0	-1.0	1.2	-2.6	-1.6	1.7	0.1	0.8	0.8	-0.7
Supplements: Calcium	0.9	1.0	3.8	0.4	0.4	-1.0	-0.5	-0.2	1.3	0.7	1.4	1.9	-0.6
Basal cell carcinoma (self-reported)	2.7	3.2	10.6	0.3	-1.8	0.4	1.7	-0.9	-3.2	-2.3	-1.8	-1.9	-1.5
Heart attack/myocardial infarction (self-reported)	1.2	1.5	4.2	-0.6	0.8	-0.7	-2.1	-1.2	1.2	1.2	1.5	1.1	1.2
Deep venous thrombosis (DVT) (self-reported)	1.6	2.1	6.2	0.5	-1.5	2.5	1.3	-0.3	1.5	-1.6	0.4	1.8	-1.5
Heart disease (siblings)	0.6	0.7	2.8	0.5	1.1	0.3	-0.5	-1.0	-0.4	1.0	-0.4	-1.7	-0.7
Alcohol drinker status: Previous	0.9	1.0	4.3	1.1	-2.1	0.8	0.8	-0.6	-1.3	-0.1	-0.6	0.9	0.1
Pack years of smoking	1.3	1.8	8.2	1.9	-1.3	-0.3	2.9	-0.7	-0.2	-1.2	-1.1	1.4	-0.1
Impedance of whole body	0.1	0.6	3.9	-0.8	0.5	0.8	-0.0	0.0	-0.5	-2.0	0.5	-0.8	-0.3
Leg fat mass (left)	0.5	2.1	8.9	2.7	0.5	-0.5	3.0	1.5	-0.4	0.3	-1.4	-0.0	0.3
Arm predicted mass (left)	0.4	1.9	6.6	1.8	-0.3	0.0	2.3	0.4	-1.3	-0.5	-2.6	-1.4	-0.5