Hub : Genes

KCNIP3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0450 0.0190 2.1e-08 0.070 0.068 0.070 0.068 0.071 7.4e-09 9.8e-09 6.3e-09 1.2e-08 5.9e-09
2 GTEx Brain Cerebellar Hemisphere 0.1570 0.1180 3.2e-03 0.081 NA 0.037 NA 0.042 4.1e-03 NA 4.1e-02 NA 3.1e-02
3 GTEx Brain Cerebellum 0.0940 0.0580 5.1e-03 0.030 NA 0.064 NA 0.040 4.6e-02 NA 5.9e-03 NA 2.4e-02
4 GTEx Brain Frontal Cortex BA9 0.0716 0.0395 3.2e-03 0.084 NA 0.029 NA 0.069 3.1e-03 NA 5.8e-02 NA 6.8e-03
5 GTEx Colon Transverse 0.0670 0.0380 1.4e-03 0.087 NA 0.076 NA 0.082 6.4e-05 NA 1.8e-04 NA 1.0e-04
6 GTEx Nerve Tibial 0.1197 0.0604 3.3e-03 0.001 NA 0.017 NA 0.000 2.9e-01 NA 2.0e-02 NA 3.0e-01
7 GTEx Pituitary 0.1220 0.0600 3.8e-04 0.021 NA -0.006 NA 0.027 9.7e-02 NA 4.7e-01 NA 6.9e-02
8 GTEx Thyroid 0.0920 0.0330 6.6e-11 0.167 NA 0.174 NA 0.172 9.2e-13 NA 2.5e-13 NA 3.4e-13
9 TCGA Breast Invasive Carcinoma 0.0075 0.0053 7.7e-03 0.008 0.007 0.003 NA 0.005 6.8e-03 8.9e-03 8.3e-02 NA 3.2e-02
10 TCGA Cervical Squamous Cell Carcinoma 0.0590 0.0440 4.3e-03 0.044 0.054 0.042 NA 0.040 3.3e-03 1.2e-03 4.0e-03 NA 4.8e-03
11 TCGA Head and Neck Squamous Cell Carcinoma 0.2804 0.0944 3.4e-12 0.063 0.097 0.103 NA 0.104 1.3e-07 4.8e-11 1.2e-11 NA 1.1e-11
12 TCGA Prostate Adenocarcinoma 0.0344 0.0187 3.3e-05 0.049 0.046 0.044 NA 0.045 7.4e-06 1.2e-05 1.8e-05 NA 1.6e-05
13 TCGA Soft Tissue Sarcoma 0.0770 0.0490 2.4e-03 0.031 0.035 0.001 NA 0.014 5.9e-03 3.6e-03 2.8e-01 NA 4.5e-02
14 TCGA Thyroid Carcinoma 0.0820 0.0370 1.4e-11 0.099 0.114 0.096 NA 0.107 7.9e-10 3.6e-11 1.2e-09 NA 1.4e-10

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.1 0.2 1.1 0.1 0.4 0.0 0.9 -0.3 -0.4 0.6 -0.3 -0.3 0.1 -0.2 -0.1 -1.1 -0.3
Bipolar Disorder or Schizophrenia 0.2 0.4 1.8 -0.5 -0.1 0.0 0.4 0.1 -1.4 -0.1 -0.0 0.2 0.6 1.0 0.5 -1.3 -0.0
Depressed Affect (Nagel 2018) 0.0 0.1 0.3 0.1 -0.2 0.0 -0.5 0.2 0.5 -0.2 0.3 0.2 0.1 0.2 0.2 -0.4 0.3
Depression (Nagel 2018) 0.3 0.5 1.9 1.2 0.3 0.0 0.5 -0.7 0.1 0.6 -0.5 -0.5 -0.5 -0.8 -0.8 -1.4 -0.2
Intelligence (Savage-Jansen 2018) 1.4 4.4 9.5 1.9 1.8 0.0 3.1 -1.5 -2.9 2.3 -1.9 -1.8 -1.3 -2.7 -1.6 -2.9 -1.6
Neuroticism (Nagel 2018) 0.2 0.5 1.7 -0.3 -0.9 0.0 -1.0 0.7 1.3 -0.8 0.9 0.7 0.6 0.3 0.7 0.0 0.8
Schizophrenia (2018) 0.2 0.5 2.0 -0.7 -0.4 0.0 -0.2 0.3 -1.3 -0.6 0.2 0.6 0.7 1.4 0.6 -0.8 0.3
Schizophrenia vs Biploar Disorder 1.9 2.5 4.2 -1.6 -1.8 0.0 -1.6 1.5 0.9 -1.9 1.6 1.6 1.5 2.0 1.5 1.8 1.6
Worry (Nagel 2018) 0.1 0.2 1.7 0.2 -0.3 0.0 -0.2 0.4 1.3 -0.2 0.6 0.3 0.1 -0.6 0.2 -0.2 0.6
Alzheimer’s Disease (in mother) 1.5 1.7 4.4 1.5 1.4 0.0 1.6 -1.2 -0.2 1.9 -1.2 -1.2 -1.1 -2.1 -1.3 -1.0 -1.1
Alzheimer’s Disease (in father) 2.0 2.1 3.8 1.8 0.6 0.0 0.8 -1.9 -1.2 1.1 -1.9 -1.6 -1.8 -0.8 -1.9 -1.9 -1.6
Alzheimer’s Disease (including proxy) 3.1 4.5 6.4 2.5 1.5 0.0 2.0 -2.4 -1.4 2.4 -2.4 -2.3 -2.3 -2.3 -2.4 -2.3 -2.1
Crohns Disease (2017) 0.2 0.5 2.2 0.3 0.3 0.0 1.5 0.1 -1.1 0.6 -0.0 -0.2 0.2 -1.1 0.2 -1.3 0.2
Irritable Bowel Disease (IBD) 0.7 1.6 5.0 1.1 1.6 0.0 2.2 -0.8 0.0 1.4 -1.1 -1.4 -1.1 -1.8 -1.0 -1.1 -1.1
Ulcerative Colitis (UC) 1.2 2.2 4.2 1.4 2.0 0.0 1.8 -1.3 1.2 1.5 -1.3 -1.7 -1.7 -1.8 -1.5 -0.6 -1.6
Major Depression (MDD) 0.2 0.2 1.1 0.1 -0.2 0.0 -1.1 -0.3 -0.8 0.2 -0.4 0.1 0.2 0.3 0.0 -0.9 -0.0
Reaction Time 0.3 0.5 1.0 -0.3 -0.2 0.0 -0.8 0.7 0.5 -0.6 0.9 0.9 0.8 1.0 0.9 -0.8 1.0
Verbal and Numeric Reasoning (VNR) 0.2 0.5 2.0 0.8 0.4 0.0 1.1 -0.4 -1.4 0.7 -0.4 -0.5 -0.2 -0.7 -0.4 -1.2 -0.2
Breast Cancer 0.1 0.3 1.6 -0.1 0.1 0.0 -1.3 0.4 -0.3 -0.9 0.3 0.5 0.1 0.7 0.1 0.0 0.4
Ovarian Cancer 0.2 0.2 0.6 -0.5 -0.4 0.0 -0.2 0.5 -0.1 0.1 0.5 0.7 0.8 0.2 0.8 -0.5 0.6
Prostate Cancer 0.1 0.2 0.8 -0.2 -0.1 0.0 -0.5 -0.2 0.0 -0.3 -0.4 -0.2 -0.2 0.8 -0.3 0.9 -0.5
Age at First Birth 0.2 0.3 1.7 -0.2 -1.1 0.0 -0.3 0.0 0.4 -0.3 -0.4 -0.2 -0.3 0.2 -0.4 1.3 -0.5
Bipolar Disorder (2011) 0.3 0.3 0.9 -0.7 -0.3 0.0 -0.4 0.5 0.5 -0.7 0.5 0.6 0.5 0.9 0.6 0.5 0.5
Body Mass Index (BMI) (2010) 0.5 0.6 1.5 -0.9 -0.7 0.0 -0.6 0.7 0.5 -0.4 1.1 0.9 1.1 0.4 1.2 -0.1 1.2
Coronary Artery Disease (CAD) 0.8 0.9 2.4 0.8 1.3 0.0 1.0 -0.3 -1.5 0.8 -1.0 -1.0 -1.0 -0.9 -0.9 -1.1 -1.0
Crohns Disease (2012) 0.7 1.2 2.2 -1.0 -1.2 0.0 -0.1 1.4 -0.5 -1.1 1.4 1.2 1.4 1.0 1.4 0.2 1.5
Mean Putamen Volume 0.2 0.3 0.6 0.5 -0.7 0.0 0.3 -0.5 0.3 0.5 -0.5 -0.5 -0.4 -0.7 -0.4 -0.7 -0.6
Fasting Glucose 3.9 4.6 7.0 2.5 1.4 0.0 2.2 -2.6 -0.8 2.5 -2.5 -2.6 -2.5 -1.5 -2.5 -2.0 -2.5
HbA1C 0.2 0.2 1.4 0.2 0.2 0.0 0.5 -0.1 1.0 0.5 0.0 -0.3 -0.4 -1.2 -0.2 0.2 -0.1
HDL Cholesterol 1.5 2.6 3.9 -1.8 -1.8 0.0 -1.9 1.6 0.5 -1.9 1.6 1.6 1.5 2.0 1.5 1.9 1.5
LDL Cholesterol 0.7 1.1 2.0 1.2 0.9 0.0 0.8 -1.4 0.1 0.9 -1.2 -1.2 -1.4 -1.3 -1.3 -0.8 -1.1
Lupus 0.1 0.2 2.2 0.2 -0.4 0.0 -0.2 0.0 -0.5 -0.1 0.1 0.0 0.1 1.5 0.0 -0.1 -0.0
Neuroticism (2016) 0.6 0.9 2.5 0.6 0.6 0.0 0.6 -0.8 -1.6 1.1 -1.2 -0.9 -0.7 -1.1 -1.0 -0.9 -1.3
Primary Biliary Cirrhosis 0.3 0.5 1.4 0.4 0.8 0.0 1.2 -0.4 -0.7 0.5 -0.6 -0.7 -0.6 -0.9 -0.3 -0.9 -0.7
Rheumatoid Arthritis 0.2 0.2 0.7 0.2 0.7 0.0 0.8 0.0 -0.1 0.8 -0.1 -0.3 -0.1 -0.6 0.1 -0.8 -0.2
Schizophrenia (2014) 0.1 0.2 0.8 -0.3 0.2 0.0 0.0 -0.0 -0.2 -0.8 0.2 0.3 0.3 0.6 0.3 -0.9 0.4
Triglycerides 1.0 1.7 2.9 1.6 1.2 0.0 1.0 -1.7 -0.2 1.1 -1.4 -1.4 -1.7 -1.5 -1.5 -1.3 -1.2
Type 2 Diabetes (T2D) (2012) 0.6 0.6 3.1 0.2 0.4 0.0 0.4 -0.5 -1.8 0.6 -1.1 -0.8 -0.6 0.1 -0.2 -1.1 -1.1
Ulcerative Colitis 0.5 0.7 2.8 0.5 1.7 0.0 1.2 -0.6 0.7 0.7 -0.7 -0.9 -1.0 -0.7 -0.8 -0.1 -0.9
Blood Eosinophil Count 0.5 4.0 29.1 -0.3 -0.8 0.0 -0.5 -0.1 3.1 -0.3 -1.4 -1.4 -1.9 0.2 -1.5 5.4 -2.6
Blood Platelet Count 0.0 0.1 0.5 0.6 0.1 0.0 0.4 0.1 0.5 0.0 0.2 -0.0 -0.2 -0.7 -0.2 -0.2 0.4
Blood Red Count 0.0 0.4 5.3 -0.0 -0.2 0.0 0.2 0.1 -2.3 0.1 -0.4 -0.1 0.1 -0.5 -0.2 -0.2 -0.1
Blood White Count 0.1 0.5 4.2 -0.2 0.3 0.0 0.4 0.5 -2.1 0.9 -0.1 0.1 0.4 -0.6 0.6 -1.0 -0.1
Heel T-Score 0.1 0.5 1.6 0.0 0.2 0.0 0.4 -0.2 0.3 -0.3 -1.2 -1.0 -1.1 0.1 -0.7 0.9 -1.3
BMI 0.9 5.2 12.7 -2.3 -1.7 0.0 -3.6 2.2 0.4 -2.4 2.7 2.8 2.6 2.0 2.5 1.2 2.7
Height 0.0 0.7 2.1 -1.0 -1.4 0.0 -0.4 0.6 -1.3 -0.2 0.2 0.8 1.4 1.3 0.4 0.5 0.3
Waist Hip Ratio (WHR) 0.1 0.3 1.6 0.6 0.9 0.0 0.3 -0.2 1.2 0.3 0.0 -0.2 -0.3 -0.8 -0.3 0.1 0.0
Systolic Blood Pressure 0.1 0.7 2.0 0.2 0.8 0.0 0.6 -0.6 -1.4 0.6 -1.0 -1.0 -1.2 -0.8 -0.8 -0.1 -1.1
Smoking Status 0.1 0.2 0.9 0.2 0.9 0.0 0.3 0.5 0.5 0.1 0.9 0.4 0.4 -0.3 0.2 0.3 0.8
Allergy or Eczema 0.5 1.2 2.5 -1.2 -0.4 0.0 -0.6 1.4 -1.2 -1.1 1.2 1.4 1.6 1.1 1.3 0.3 1.2
Cardiovascular Disease 0.3 1.0 4.1 -1.0 -0.2 0.0 -1.6 0.5 1.4 -1.4 0.5 0.4 -0.2 0.9 0.3 2.0 0.2
Hypothyroidism (self reported) 2.2 5.2 12.2 2.3 3.5 0.0 2.6 -2.1 -1.1 2.1 -2.4 -2.5 -2.4 -2.3 -2.6 -1.3 -2.6
Respiratory disease 0.1 0.2 1.0 0.3 0.4 0.0 0.4 0.5 -0.8 0.5 0.3 -0.0 0.1 -0.4 0.3 -1.0 0.0
Type 2 Diabetes (T2D) (2018) 0.2 0.3 1.4 0.5 0.8 0.0 0.8 -0.6 1.2 0.1 -0.3 -0.5 -0.8 -0.3 -0.6 -0.2 -0.3
Lung FEV1/FVC ratio 0.0 0.2 1.1 0.0 -0.5 0.0 -0.7 -0.2 1.0 -0.3 -0.3 -0.2 -0.5 0.4 -0.1 0.3 -0.1
Lung FVC 0.1 0.3 1.3 0.4 0.1 0.0 0.5 -0.2 0.3 1.1 -0.5 -0.6 -0.4 -0.5 -0.4 0.7 -0.7
Neuroticism 0.1 0.3 0.9 -0.3 -0.9 0.0 -0.6 0.6 0.5 -0.5 0.6 0.6 0.7 -0.2 0.5 -0.3 0.8
Chronotype (morning person) 0.4 0.8 3.2 -1.1 -0.8 0.0 -1.7 0.6 0.9 -0.8 0.2 0.4 0.2 1.0 0.7 1.8 0.1
Hair Pigment 0.0 0.8 2.2 -1.3 0.1 0.0 -0.7 1.1 -0.7 -0.5 0.8 1.0 1.2 0.8 1.5 -0.1 0.9
Tanning 0.0 0.5 2.7 0.6 -0.2 0.0 -0.8 0.6 1.6 -0.0 0.9 0.7 0.5 0.4 -0.2 0.7 0.9
Hand grip strength (left) 0.3 0.7 1.8 0.6 0.2 0.0 0.7 -1.0 -0.3 1.1 -1.0 -1.1 -1.1 -0.1 -1.1 0.2 -1.4
Number of treatments/medications taken 0.2 0.4 1.0 0.9 1.0 0.0 0.1 -0.5 0.5 -0.2 -0.2 -0.4 -0.7 -1.0 -0.7 -0.6 -0.1
Average weekly spirits intake 0.4 0.5 1.5 -0.2 0.1 0.0 -0.3 0.6 -0.4 -0.9 1.0 0.9 1.0 1.0 0.6 -0.3 1.2
Sensitivity / hurt feelings 0.4 0.6 1.6 0.9 0.7 0.0 0.2 -0.9 -0.3 0.2 -1.1 -0.8 -0.9 -0.7 -1.1 -1.3 -0.8
Frequency of depressed mood in last 2 weeks 0.2 0.2 0.6 -0.2 -0.2 0.0 -0.5 0.3 0.0 -0.5 0.6 0.6 0.6 0.8 0.4 -0.4 0.8
Hearing difficulty/problems: Yes 0.1 0.1 0.3 0.1 0.2 0.0 0.0 -0.3 0.2 -0.0 -0.4 -0.3 -0.3 -0.6 -0.5 -0.1 -0.3
Relative age of first facial hair 0.3 0.7 1.2 -1.1 -0.9 0.0 -0.9 0.7 1.0 -0.7 0.7 0.8 0.9 0.5 1.0 1.0 0.7
Other serious medical condition/disability diagnosed by doctor 0.1 0.2 0.7 0.1 -0.4 0.0 -0.7 0.2 0.8 -0.4 0.4 0.4 0.3 -0.4 -0.1 -0.1 0.5
Ever used hormone-replacement therapy (HRT) 0.5 0.7 1.6 1.3 0.7 0.0 0.5 -1.2 0.4 1.1 -0.6 -0.9 -0.9 -0.4 -1.3 -0.4 -0.9
Ever had hysterectomy (womb removed) 0.2 0.2 0.7 -0.4 -0.9 0.0 0.4 0.6 -0.6 0.0 0.3 0.3 0.6 0.3 0.6 0.4 0.2
Systolic blood pressure, automated reading 0.2 0.5 1.3 0.7 0.2 0.0 0.4 -0.7 -1.1 0.5 -0.8 -0.8 -1.0 -0.4 -0.7 -0.5 -0.8
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 1.6 1.0 -0.4 0.0 0.1 -1.2 0.3 0.7 -0.7 -0.7 -0.9 0.1 -0.9 -1.2 -0.7
Angina 1.1 1.5 3.0 1.4 1.5 0.0 1.2 -1.7 -0.1 0.6 -1.4 -1.3 -1.4 -0.9 -1.4 -1.7 -0.9
Medication for hormone replacement therapy 0.7 0.7 2.9 0.1 -1.0 0.0 -1.4 0.4 1.7 -0.7 1.0 0.8 0.5 0.5 0.3 0.9 1.0
Vitamin and mineral supplements 2.2 3.0 6.0 1.6 1.2 0.0 1.3 -1.8 -1.1 1.1 -2.5 -2.1 -2.3 -2.0 -2.3 -0.7 -2.2
Supplements: Zinc 0.2 0.2 0.9 -0.3 0.1 0.0 0.3 0.1 0.9 0.1 0.5 0.5 0.6 0.6 0.4 -0.2 0.5
Medication: Co-codamol 0.2 0.3 0.9 0.3 0.4 0.0 -0.0 -0.6 -0.4 0.6 -0.7 -0.5 -0.4 -0.9 -0.6 -0.3 -0.5
Medication: Metformin 0.5 0.7 2.3 0.8 1.5 0.0 1.0 -0.5 -0.3 1.3 -0.4 -0.7 -0.9 -0.8 -0.5 -0.9 -0.6
Diabetes (father) 1.2 1.5 3.2 -1.6 -1.8 0.0 -1.0 1.3 -0.3 -1.3 1.2 1.4 1.4 1.1 1.5 1.0 1.3
Diabetes (mother) 0.4 0.6 2.2 0.6 1.0 0.0 1.5 -0.6 -0.8 1.1 -0.3 -0.6 -0.2 -0.3 -0.3 -1.1 -0.5
Severe depression (siblings) 0.5 0.6 1.9 -0.5 -0.1 0.0 -0.4 0.5 1.4 -1.0 1.1 0.8 0.8 0.3 0.6 0.4 1.2
Pack years adult smoking proportion 0.3 0.5 1.0 -0.8 -0.1 0.0 0.2 1.0 0.2 -0.6 1.0 0.9 1.0 0.4 0.9 0.2 0.9
Impedance of leg (right) 0.5 2.4 5.1 1.7 1.2 0.0 1.1 -1.8 0.4 0.8 -1.9 -1.9 -2.1 -1.9 -2.3 -0.1 -1.8
Leg fat-free mass (left) 0.2 1.1 2.4 -0.9 -1.1 0.0 -1.6 0.9 0.4 -1.1 1.2 1.4 1.4 1.1 1.0 0.3 1.3
Trunk fat percentage 0.3 1.3 4.1 1.4 1.1 0.0 0.5 -1.3 -0.7 0.6 -1.2 -1.1 -1.1 -2.0 -1.3 -1.6 -0.8
Hand grip strength (right) 0.3 0.7 1.4 0.8 0.3 0.0 0.6 -1.1 -0.5 1.0 -1.0 -1.1 -1.1 -0.6 -1.2 -0.1 -1.2
Townsend deprivation index at recruitment 0.5 0.7 3.5 1.1 1.1 0.0 1.1 -0.8 -0.1 0.8 -0.4 -0.6 -0.7 -0.3 -0.8 -1.9 -0.4
Current tobacco smoking 0.2 0.3 1.4 0.6 0.5 0.0 0.6 0.1 -0.6 0.3 0.4 0.2 0.3 -0.7 0.1 -1.2 0.7
Average weekly fortified wine intake 0.9 1.0 2.2 1.3 0.9 0.0 0.8 -1.5 1.1 0.9 -0.9 -1.0 -1.0 -0.8 -1.3 -1.3 -0.8
Maternal smoking around birth 0.1 0.1 0.2 0.2 0.3 0.0 -0.2 -0.3 -0.3 -0.2 -0.4 -0.3 -0.5 0.1 -0.4 -0.4 -0.3
Fed-up feelings 0.6 1.1 1.8 -1.1 -1.3 0.0 -1.2 1.0 0.7 -1.1 1.2 1.3 1.2 0.9 1.2 0.4 1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 1.2 0.7 0.6 0.0 1.0 -0.3 0.2 0.5 -0.0 -0.2 -0.2 -0.8 -0.3 -1.1 0.2
Relative age voice broke 0.2 0.3 1.4 -0.4 -0.7 0.0 -0.1 0.1 1.2 -0.5 0.5 0.5 0.5 0.4 0.5 0.5 0.6
Taking other prescription medications 0.6 0.9 1.5 1.0 1.2 0.0 0.5 -0.9 -0.2 0.8 -1.0 -1.1 -1.2 -1.2 -1.2 -0.5 -1.1
Age when periods started (menarche) 0.5 1.2 3.9 -1.6 -0.4 0.0 -0.2 1.3 -0.4 -1.5 0.7 0.8 0.8 2.0 1.1 1.7 0.4
Bilateral oophorectomy (both ovaries removed) 3.8 4.4 7.7 -2.0 -2.8 0.0 -1.6 2.0 2.4 -2.2 2.2 2.2 2.2 2.2 2.1 2.1 2.1
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.9 3.4 1.3 1.4 0.0 1.0 -1.5 0.4 1.4 -1.5 -1.7 -1.7 -1.8 -1.6 -0.6 -1.7
Tinnitus: Yes, but not now, but have in the past 0.7 0.8 1.9 -0.4 -0.8 0.0 -0.6 0.6 1.4 -0.6 1.3 1.0 1.0 0.8 0.7 0.2 1.3
Qualifications: CSEs or equivalent 0.6 0.8 2.2 -1.3 -1.5 0.0 -0.8 0.9 0.5 -0.2 0.8 0.9 1.0 0.1 1.1 1.1 0.7
Serious illness, injury or assault to yourself 0.6 0.7 2.4 -0.3 0.2 0.0 -0.2 1.1 -0.2 -0.5 1.5 1.1 1.3 0.2 1.0 -0.4 1.5
High blood pressure 0.3 0.7 2.8 -0.5 -0.8 0.0 -1.1 0.2 1.7 -1.3 0.3 0.2 -0.2 0.6 0.0 1.6 0.3
Hayfever, allergic rhinitis or eczema 0.5 1.1 2.0 -1.2 -0.5 0.0 -1.1 1.2 -0.4 -1.3 1.1 1.3 1.2 1.4 1.1 0.8 1.1
Multivitamins +/- minerals 4.2 5.3 9.1 -2.3 -1.8 0.0 -2.1 2.5 1.6 -1.9 2.9 2.6 2.6 3.0 2.9 1.6 2.6
Stomach or abdominal pain in last month 0.8 1.0 2.3 -0.9 -1.4 0.0 -0.9 1.0 1.3 -1.5 0.9 0.9 0.7 1.2 0.7 1.2 0.8
Supplements: Glucosamine 0.1 0.1 0.3 0.4 0.1 0.0 0.3 -0.0 0.1 0.5 0.1 0.0 0.3 -0.4 -0.4 0.5 -0.2
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 1.7 -1.2 -0.2 0.0 0.6 1.2 -0.3 -0.9 0.9 0.9 1.1 0.9 1.3 0.8 0.9
Medication: Atenolol 0.7 0.9 2.1 1.2 0.8 0.0 0.3 -1.4 -1.0 -0.4 -1.1 -0.9 -1.2 -0.2 -1.5 -1.0 -0.5
Medication: Levothyroxine sodium 0.1 0.1 0.5 -0.5 -0.1 0.0 -0.3 0.4 -0.4 -0.4 0.2 0.3 0.4 0.2 0.3 0.7 0.1
Sitting height 0.1 0.5 2.9 -0.7 -0.7 0.0 -0.6 0.5 0.8 -0.5 0.4 0.5 0.7 0.9 0.2 1.7 0.1
Chronic bronchitis/emphysema (father) 0.1 0.1 0.4 -0.1 0.6 0.0 0.6 0.2 -0.0 -0.5 0.0 0.2 0.2 0.1 0.1 -0.2 0.2
High blood pressure (mother) 0.2 0.3 0.5 -0.7 -0.6 0.0 -0.0 0.6 0.5 -0.4 0.6 0.6 0.6 -0.2 0.6 0.1 0.7
Body mass index (BMI) 0.1 0.2 0.9 -0.0 -0.0 0.0 -0.8 0.1 -0.2 -0.2 0.5 0.5 0.5 -0.6 0.4 -1.0 0.8
Impedance of leg (left) 0.4 2.1 4.2 1.5 1.2 0.0 1.2 -1.7 0.2 0.8 -1.9 -1.9 -2.0 -1.5 -2.0 -0.1 -1.8
Leg predicted mass (left) 0.2 1.1 2.5 -0.9 -1.1 0.0 -1.6 0.9 0.4 -1.1 1.1 1.4 1.4 1.0 1.0 0.3 1.2
Trunk fat mass 0.1 0.4 1.4 0.8 0.5 0.0 -0.2 -0.8 -0.3 0.0 -0.5 -0.4 -0.4 -1.2 -0.7 -1.0 -0.3
Waist circumference 0.1 0.2 1.6 0.5 0.3 0.0 -0.4 -0.3 0.4 -0.1 0.1 0.2 0.1 -0.8 -0.1 -1.3 0.5
Number of incorrect matches in round 0.1 0.2 1.6 -0.1 -0.2 0.0 -0.1 0.1 0.2 -0.5 -0.3 -0.1 -0.4 1.3 -0.1 0.6 -0.5
Past tobacco smoking 0.2 0.3 2.7 -0.8 -1.6 0.0 -0.2 0.4 -0.4 -0.2 -0.2 0.1 0.3 0.5 0.6 0.1 -0.3
Alcohol usually taken with meals 1.1 1.7 3.6 -1.2 -1.2 0.0 -1.6 1.2 0.7 -1.9 1.4 1.5 1.3 1.4 1.3 1.0 1.6
Nervous feelings 0.2 0.3 3.2 -0.1 -0.1 0.0 -0.2 0.4 1.8 -0.4 0.4 0.2 -0.0 -0.3 0.1 0.8 0.2
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.1 0.7 0.2 -0.1 0.0 -0.8 -0.4 0.8 0.0 -0.1 0.0 -0.1 -0.2 -0.3 -0.3 0.1
Hearing difficulty/problems with background noise 0.7 1.2 2.2 1.4 1.4 0.0 0.4 -1.4 0.8 0.1 -1.1 -1.0 -1.3 -1.2 -1.4 -1.5 -0.7
Hair/balding pattern: Pattern 2 0.1 0.1 0.4 -0.5 -0.0 0.0 0.0 0.6 0.3 0.0 0.3 0.4 0.6 -0.4 0.4 0.4 0.2
Had menopause 3.1 3.9 7.3 2.1 1.7 0.0 2.3 -1.7 -2.7 2.4 -1.8 -1.8 -1.3 -2.4 -1.6 -2.5 -1.7
Had other major operations 0.5 0.7 1.3 -0.8 -0.6 0.0 -0.6 1.0 0.1 -1.0 0.9 1.0 1.1 1.1 0.7 0.4 0.9
Forced vital capacity (FVC) 0.2 0.6 3.8 -0.7 -1.3 0.0 -0.7 0.4 1.0 -0.3 0.2 0.3 0.4 0.8 0.1 1.9 -0.2
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.7 1.4 0.6 0.1 0.0 -0.1 -1.0 0.9 0.5 -1.1 -1.0 -1.2 -1.1 -1.1 -0.0 -1.2
Ever unenthusiastic/disinterested for a whole week 1.1 1.4 7.2 1.6 1.0 0.0 1.5 -1.3 -0.5 1.1 -0.5 -0.7 -0.5 -1.2 -0.8 -2.7 0.0
Qualifications: None of the above 2.2 4.6 9.7 2.4 2.8 0.0 1.6 -2.5 0.1 1.4 -2.6 -2.6 -3.1 -1.2 -2.8 -1.0 -2.5
Financial difficulties in last 2 years 0.6 0.9 1.6 1.3 1.0 0.0 0.5 -1.1 1.2 0.3 -0.6 -0.9 -1.3 -0.7 -1.2 -1.1 -0.7
Mouth/teeth dental problems 0.2 0.3 1.5 -0.2 -0.6 0.0 -0.2 0.5 -1.2 -0.2 0.4 0.5 0.7 0.0 0.4 -0.4 0.5
Heart attack 0.4 0.5 1.9 1.0 0.5 0.0 0.2 -1.1 1.4 0.3 -0.5 -0.6 -0.8 -0.6 -0.9 -0.5 -0.3
Allergy 0.2 0.5 1.1 0.7 0.1 0.0 0.8 -0.8 -0.1 0.7 -0.9 -0.8 -0.7 -1.0 -0.8 -0.2 -0.7
Pain all over the body in last month 0.4 0.5 0.9 0.8 0.7 0.0 0.3 -0.6 -0.8 -0.0 -1.0 -0.6 -0.6 -1.0 -0.8 -0.8 -0.5
Diabetes (self-reported) 0.2 0.4 1.1 0.4 0.9 0.0 0.7 -0.6 1.0 0.1 -0.5 -0.5 -0.9 -0.7 -0.7 0.0 -0.4
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.0 -0.4 -0.9 0.0 -0.9 0.6 1.0 -0.7 0.7 0.7 0.5 0.6 0.5 0.9 0.6
Medication: Ramipril 0.3 0.4 1.2 0.3 0.7 0.0 1.1 -0.3 -0.4 0.4 -0.7 -0.8 -0.8 -1.0 -0.6 -0.1 -0.8
Medication: Simvastatin 1.0 1.4 3.4 1.2 1.0 0.0 0.3 -1.6 1.2 0.4 -1.5 -1.4 -1.8 -1.3 -1.6 -0.3 -1.4
Fluid intelligence score 0.4 0.9 5.0 0.3 0.9 0.0 1.6 0.0 -2.2 0.8 -0.5 -0.4 0.1 -1.3 -0.1 -0.9 -0.4
Illnesses of siblings 1.8 2.5 4.1 -1.5 -1.7 0.0 -1.7 1.7 1.7 -2.0 1.9 1.8 1.5 0.9 1.5 1.3 2.0
Neuroticism score 0.2 0.4 1.1 -0.2 -0.8 0.0 -0.6 0.6 0.9 -0.3 0.8 0.8 0.8 -0.1 0.7 -0.4 1.0
Weight 0.1 0.5 1.2 -0.5 -0.7 0.0 -1.1 0.6 0.4 -0.8 0.8 1.0 1.0 0.2 0.7 -0.0 1.0
Impedance of arm (right) 0.1 0.6 1.1 0.5 0.9 0.0 0.9 -0.7 -0.6 0.4 -1.0 -1.0 -1.0 -1.1 -0.9 0.0 -1.1
Arm fat percentage (right) 0.0 0.2 1.0 0.2 0.3 0.0 -0.4 -0.1 -0.5 -0.2 -0.0 0.1 0.0 -1.0 0.1 -1.0 0.3
Trunk fat-free mass 0.2 1.1 1.9 -0.8 -1.4 0.0 -1.3 0.8 1.0 -1.1 1.1 1.2 1.2 1.4 0.8 0.8 1.1
Hip circumference 0.1 0.2 0.6 -0.1 -0.5 0.0 -0.7 0.2 -0.2 -0.6 0.4 0.6 0.6 0.0 0.3 -0.7 0.7
Time employed in main current job 0.3 0.4 1.4 0.2 0.3 0.0 0.2 -0.4 -1.2 0.7 -0.8 -0.7 -0.6 -0.2 -0.4 -0.8 -1.0
Alcohol intake versus 10 years previously 0.9 1.4 2.8 -1.6 -1.2 0.0 -1.7 0.9 0.8 -1.1 1.0 1.2 1.2 1.4 1.2 1.3 0.9
Father’s age at death 0.3 0.4 1.3 0.9 0.1 0.0 0.2 -0.6 1.1 0.0 -0.3 -0.8 -1.0 0.1 -0.8 0.3 -0.6
Worrier / anxious feelings 0.5 1.0 3.0 -0.6 -1.7 0.0 -1.0 1.1 0.7 -0.8 1.2 1.2 1.2 0.0 1.0 -0.2 1.4
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 1.2 -0.2 0.1 0.0 -0.2 0.6 0.3 -0.5 0.8 0.8 0.8 -0.3 0.6 -0.4 1.1
Falls in the last year 0.3 0.4 0.9 -0.7 -0.3 0.0 -0.7 0.7 0.2 -0.3 0.8 0.8 0.9 0.1 0.8 0.1 0.8
Hair/balding pattern: Pattern 3 0.2 0.3 0.7 0.5 0.5 0.0 0.6 -0.7 -0.3 0.3 -0.7 -0.8 -0.9 -0.3 -0.8 0.0 -0.8
Number of live births 3.9 5.5 8.7 3.0 1.9 0.0 2.9 -2.4 -1.1 1.9 -2.6 -2.5 -2.7 -2.3 -2.8 -2.8 -2.2
Forced expiratory volume in 1-second (FEV1) 0.2 0.8 4.0 -0.9 -1.4 0.0 -1.1 0.5 0.9 -0.5 0.2 0.4 0.4 1.0 0.2 2.0 -0.0
Pulse rate 0.1 0.2 0.8 0.3 -0.1 0.0 -0.4 -0.5 0.9 0.3 -0.0 -0.3 -0.4 0.1 -0.4 0.5 -0.4
Happiness 0.3 0.3 1.5 -0.1 0.1 0.0 1.2 0.4 -0.7 0.9 0.3 0.1 0.6 -0.6 0.4 -0.8 0.3
Noisy workplace 2.7 3.3 6.1 1.8 1.3 0.0 0.9 -2.4 -1.4 1.5 -2.5 -2.1 -2.3 -1.3 -2.2 -1.7 -2.3
Qualifications: A levels/AS levels or equivalent 0.1 0.3 1.1 -0.7 -0.3 0.0 0.1 1.0 -0.7 -0.3 0.5 0.5 0.7 -0.1 0.6 0.6 0.3
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 1.4 0.4 0.6 0.0 0.4 -0.2 1.2 0.5 0.2 0.0 0.1 0.2 -0.1 -0.1 0.2
Mouth/teeth dental problems: Dentures 1.3 2.2 3.5 1.4 1.6 0.0 1.7 -1.9 0.8 1.3 -1.9 -1.8 -1.8 -1.0 -1.9 -0.1 -1.9
Asthma 0.4 0.7 2.0 0.8 1.1 0.0 0.8 -0.4 -0.7 1.3 -0.5 -0.7 -0.7 -1.1 -0.4 -1.4 -0.7
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 1.8 -0.6 0.2 0.0 -0.9 1.0 -0.1 -0.4 1.2 1.1 1.2 0.5 1.0 -0.2 1.3
Medication: Cholesterol lowering 0.9 1.4 2.8 1.3 1.6 0.0 0.7 -1.3 0.7 0.5 -1.1 -1.2 -1.7 -1.5 -1.6 -0.4 -1.1
Depression (self-reported) 0.1 0.2 1.4 0.6 -0.0 0.0 0.0 -0.0 -0.0 0.2 -0.1 -0.2 -0.3 -1.2 -0.3 -0.6 0.1
Medication: Lansoprazole 3.5 3.9 6.1 2.0 2.0 0.0 2.3 -2.1 -1.2 2.1 -2.4 -2.3 -2.2 -1.6 -2.2 -1.4 -2.5
Prospective memory result 0.4 0.6 1.5 1.0 1.2 0.0 -0.1 -1.0 0.3 0.6 -0.6 -0.7 -0.9 -0.2 -0.9 -0.9 -0.6
Lung cancer (father) 1.1 1.2 3.1 0.9 0.9 0.0 1.2 -1.0 -0.9 1.8 -1.3 -1.2 -1.0 -0.8 -1.1 -1.0 -1.6
Illnesses of mother 0.2 0.2 0.4 -0.1 0.6 0.0 -0.4 0.5 -0.3 -0.7 0.6 0.4 0.3 0.5 0.5 -0.0 0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.2 0.8 0.2 -0.5 0.0 -0.0 -0.3 -0.0 0.3 -0.6 -0.4 -0.3 -0.1 -0.6 0.9 -0.7
Pulse wave Arterial Stiffness index 0.7 0.8 1.4 1.2 0.6 0.0 0.3 -1.0 -0.4 0.8 -1.0 -1.0 -1.1 -1.1 -1.1 -0.8 -0.9
Impedance of arm (left) 0.4 1.8 3.2 1.2 1.4 0.0 1.7 -1.3 -0.3 1.1 -1.6 -1.6 -1.6 -1.8 -1.6 -0.4 -1.6
Arm fat mass (right) 0.0 0.2 0.5 -0.1 -0.1 0.0 -0.7 0.1 -0.2 -0.4 0.3 0.5 0.4 -0.5 0.3 -0.6 0.6
Trunk predicted mass 0.2 1.0 1.7 -0.8 -1.3 0.0 -1.2 0.8 0.9 -1.0 1.0 1.2 1.2 1.3 0.8 0.7 1.0
Standing height 0.1 0.9 3.5 -0.8 -1.2 0.0 -0.6 0.6 1.4 -1.0 0.5 0.7 0.9 1.5 0.2 1.9 0.3
Length of working week for main job 1.3 1.4 4.1 -1.5 -2.0 0.0 -1.9 0.7 0.2 -1.1 0.6 1.0 0.9 1.6 1.0 1.3 0.6
Exposure to tobacco smoke at home 0.3 0.3 2.2 -0.3 0.5 0.0 0.0 0.2 1.5 -0.6 0.5 0.2 0.0 0.2 0.1 0.8 0.3
Breastfed as a baby 1.3 1.6 3.2 -1.2 -1.7 0.0 0.0 1.6 0.9 -1.1 1.6 1.5 1.8 0.7 1.6 0.9 1.6
Tense / ‘highly strung’ 0.1 0.2 1.4 0.5 -0.2 0.0 -0.6 -0.0 1.2 -0.1 0.2 0.1 -0.1 -0.4 -0.1 0.1 0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 1.4 0.9 0.0 0.0 -0.3 -0.5 1.2 -0.2 0.2 0.0 -0.3 0.0 -0.3 -1.2 0.5
Hair/balding pattern: Pattern 4 0.3 0.7 2.0 -1.1 0.2 0.0 -0.7 1.0 -0.1 -0.5 1.2 1.1 1.2 0.3 1.4 0.3 1.1
Birth weight of first child 4.2 7.7 11.9 2.7 2.6 0.0 3.5 -3.1 -2.2 3.0 -3.2 -3.1 -2.8 -2.2 -2.9 -2.6 -3.2
Peak expiratory flow (PEF) 2.1 4.9 13.6 -2.4 -2.5 0.0 -2.5 1.9 3.3 -1.7 2.0 1.8 1.8 1.9 1.7 3.7 1.5
Pulse wave reflection index 0.1 0.1 0.2 0.2 0.0 0.0 -0.1 -0.1 0.1 0.4 -0.4 -0.3 -0.4 -0.4 -0.4 0.3 -0.4
Ever highly irritable/argumentative for 2 days 0.1 0.2 0.9 -0.3 -0.3 0.0 -0.6 -0.0 0.9 -0.8 0.1 0.3 0.1 0.2 0.2 0.2 0.3
Loud music exposure frequency 1.3 1.4 3.3 1.4 1.5 0.0 1.0 -1.8 -0.6 0.8 -1.1 -1.1 -1.2 -0.8 -1.5 -1.5 -0.9
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 4.2 0.3 0.6 0.0 1.2 -0.0 -2.1 1.3 -0.4 -0.3 0.3 -1.4 0.0 -1.7 -0.3
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 0.7 -0.7 -0.6 0.0 -0.5 0.1 0.8 -0.9 -0.0 0.1 -0.1 0.8 0.2 0.8 -0.1
Blood clot in the leg (DVT) 0.5 0.6 1.7 0.5 0.8 0.0 1.0 -1.0 1.3 0.8 -0.6 -0.8 -0.7 -0.6 -0.6 -0.5 -0.8
Medication: Paracetamol 0.1 0.2 0.7 0.6 0.6 0.0 -0.3 -0.2 0.5 -0.0 0.1 0.0 -0.2 -0.5 -0.2 -0.8 0.3
Headache pain in last month 0.3 0.6 3.4 0.5 0.5 0.0 0.5 -0.3 -1.9 0.4 -0.7 -0.6 -0.6 -0.4 -0.4 -1.2 -0.7
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.4 -0.7 -0.8 0.0 -0.1 0.9 -0.3 -0.1 0.8 0.8 1.2 0.6 1.0 0.1 0.9
Glaucoma (self-reported) 0.1 0.1 0.4 0.2 0.4 0.0 -0.0 -0.1 -0.6 0.2 -0.3 -0.2 -0.2 -0.6 -0.4 0.0 -0.2
Gout (self-reported) 0.3 0.4 1.7 0.5 -0.2 0.0 0.5 -0.7 -1.0 0.2 -0.6 -0.5 -0.4 -1.3 -0.7 -0.6 -0.2
Hypothyroidism/myxoedema (self-reported) 1.8 3.6 7.1 2.0 2.7 0.0 1.9 -1.9 -0.7 2.0 -2.0 -2.1 -2.0 -1.9 -2.3 -1.0 -2.2
Medication: Amlodipine 0.2 0.2 1.8 -0.1 -0.3 0.0 -0.6 -0.3 1.4 -0.0 -0.1 -0.0 -0.1 -0.1 -0.2 0.7 -0.1
Medication: Ventolin 100micrograms inhaler 0.4 0.6 3.7 -0.7 0.5 0.0 -0.1 0.9 -1.9 0.4 0.6 0.5 0.8 -0.2 0.9 -0.4 0.4
Birth weight 2.1 4.6 7.1 2.1 2.2 0.0 2.7 -2.1 -1.5 2.1 -2.5 -2.5 -2.3 -1.9 -2.4 -1.6 -2.5
Chronic bronchitis/emphysema (mother) 0.4 0.4 1.6 -0.6 -0.3 0.0 -1.0 0.1 1.3 -0.8 -0.2 0.1 -0.4 0.7 -0.2 1.2 -0.4
High blood pressure (siblings) 0.3 0.4 2.7 -0.1 0.2 0.0 0.8 -0.3 -1.6 0.6 -0.8 -0.6 -0.2 -0.5 -0.2 0.1 -1.0
Forced vital capacity (FVC), Best measure 0.1 0.4 1.2 0.5 0.1 0.0 0.7 -0.5 -0.0 0.8 -0.8 -0.8 -0.6 -0.3 -0.9 0.8 -1.1
Body fat percentage 0.3 1.2 4.2 1.3 1.1 0.0 0.3 -1.3 -0.5 0.5 -1.1 -1.0 -1.1 -2.0 -1.2 -1.6 -0.7
Leg fat percentage (right) 0.2 0.7 3.1 1.1 0.8 0.0 -0.4 -1.0 0.1 0.2 -0.6 -0.6 -0.8 -1.8 -0.9 -1.2 -0.2
Arm fat-free mass (right) 0.2 1.0 1.8 -0.8 -1.3 0.0 -1.3 0.8 0.8 -1.1 1.1 1.3 1.3 1.1 0.7 0.5 1.1
Exposure to tobacco smoke outside home 0.1 0.1 0.2 0.4 0.4 0.0 0.5 -0.2 -0.4 0.2 -0.2 -0.3 -0.3 -0.2 -0.3 0.1 -0.2
Comparative body size at age 10 0.3 0.8 1.7 -0.8 -0.8 0.0 -0.4 1.0 -0.9 0.2 1.1 1.1 1.3 0.4 1.3 -0.6 1.2
Number of full brothers 0.4 0.4 4.6 0.4 0.1 0.0 -0.4 -0.4 2.1 -0.4 -0.2 -0.2 -0.6 -0.3 -0.6 0.5 0.0
Worry too long after embarrassment 0.4 0.7 1.8 -0.8 -1.4 0.0 -1.0 0.8 1.1 -0.9 0.7 0.8 0.9 0.3 0.7 0.7 0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.3 1.9 0.3 -0.1 0.0 -0.9 0.1 0.7 -0.6 0.6 0.4 0.2 1.4 -0.0 0.1 0.5
Wheeze or whistling in the chest in last year 0.1 0.3 1.5 -0.2 0.0 0.0 -0.5 0.5 1.2 -0.4 0.7 0.5 0.2 0.1 0.4 -0.1 0.5
Number of children fathered 0.3 0.3 2.4 0.1 -0.7 0.0 -1.0 -0.1 1.6 -0.6 0.1 0.0 -0.2 0.4 -0.2 0.5 0.0
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 3.0 -0.6 -1.0 0.0 -1.1 0.5 1.7 -0.7 0.9 0.7 0.6 1.0 0.5 1.2 0.7
Age at first live birth 3.1 5.4 9.4 -2.8 -2.4 0.0 -2.2 2.7 0.6 -1.6 2.7 2.7 2.9 1.5 3.1 2.4 2.6
Pulse wave peak to peak time 0.6 0.7 1.2 -1.0 -0.7 0.0 -0.3 0.9 0.5 -0.9 1.0 0.9 1.0 1.1 1.0 0.9 0.9
Health satisfaction 0.2 0.3 2.1 0.6 0.3 0.0 0.1 0.0 -0.3 0.3 0.5 0.3 0.4 -0.4 0.1 -1.4 0.7
Shortness of breath walking on level ground 0.5 0.6 3.2 1.1 1.1 0.0 0.2 -0.8 -0.4 0.8 -0.5 -0.6 -0.7 -0.0 -0.6 -1.8 -0.4
Qualifications: College or University degree 1.1 3.3 6.8 -1.9 -1.7 0.0 -0.1 2.4 -0.0 -1.5 2.4 2.1 2.6 1.4 2.4 1.4 2.3
Eye problems/disorders: None of the above 0.2 0.2 0.7 0.3 0.8 0.0 0.3 -0.1 0.3 0.8 -0.3 -0.3 -0.3 -0.7 -0.1 -0.2 -0.3
Mouth/teeth dental problems: Loose teeth 0.9 1.1 1.6 -1.1 -0.8 0.0 -1.1 1.3 0.2 -0.7 1.3 1.2 1.2 1.0 1.3 1.0 1.2
Emphysema/chronic bronchitis 2.8 3.2 5.3 -1.6 -1.3 0.0 -1.9 2.3 1.1 -1.9 2.1 1.9 1.7 2.1 2.0 1.6 2.0
Medication for pain relief, constipation, heartburn 1.2 2.1 5.3 -1.7 -2.3 0.0 -1.1 1.7 0.1 -1.2 1.2 1.3 1.5 1.6 1.5 2.1 1.0
Neck or shoulder pain in last month 0.0 0.1 0.3 0.3 0.1 0.0 -0.4 -0.2 0.2 -0.1 -0.1 -0.2 -0.4 0.5 -0.2 -0.0 -0.2
Medication: Blood pressure 0.1 0.2 0.5 0.3 0.4 0.0 0.3 -0.5 -0.1 -0.2 -0.5 -0.5 -0.7 -0.5 -0.5 -0.4 -0.5
Angina (self-reported) 1.4 1.8 3.5 1.6 1.6 0.0 1.4 -1.9 -0.1 0.8 -1.5 -1.4 -1.5 -1.0 -1.5 -1.8 -1.0
Migraine (self-reported) 0.2 0.2 0.6 -0.3 -0.1 0.0 0.5 0.5 -0.8 -0.0 0.6 0.4 0.6 -0.2 0.6 -0.4 0.7
Medication: Ibuprofen 1.5 1.8 3.7 -1.4 -0.1 0.0 -1.0 1.7 -0.1 -1.3 1.8 1.8 1.9 1.2 1.6 0.5 1.9
Medication: Allopurinol 0.3 0.3 1.6 0.7 -0.1 0.0 -0.2 -0.6 -0.4 0.1 -0.3 -0.3 -0.4 -1.3 -0.6 -1.1 0.1
Medication: Omeprazole 1.3 1.5 2.5 0.9 1.3 0.0 0.5 -1.4 -1.5 1.2 -1.6 -1.3 -1.2 -1.3 -1.3 -1.4 -1.5
Medication: Seretide 50 evohaler 0.5 0.6 1.4 -0.9 -0.8 0.0 -0.8 1.1 -0.1 -0.2 1.0 0.9 1.1 0.3 1.2 0.2 0.8
Mean time to correctly identify matches 0.3 0.6 2.3 1.1 1.4 0.0 0.8 -0.6 0.5 0.6 -0.2 -0.5 -0.6 -0.6 -0.6 -1.5 -0.3
Heart disease (mother) 1.6 1.9 3.8 1.3 0.6 0.0 1.1 -1.8 -0.8 1.6 -1.9 -1.7 -1.6 -0.7 -1.7 -0.8 -1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.8 2.7 1.6 0.5 0.0 0.2 -1.0 -0.9 0.8 -0.7 -0.8 -0.7 -0.9 -1.2 -1.6 -0.4
Whole body fat mass 0.1 0.3 1.1 0.7 0.4 0.0 -0.4 -0.7 -0.1 -0.1 -0.4 -0.3 -0.4 -1.1 -0.6 -0.9 -0.1
Leg fat mass (right) 0.1 0.3 0.9 0.7 0.3 0.0 -0.8 -0.6 0.1 -0.1 -0.2 -0.1 -0.3 -0.9 -0.5 -0.9 0.1
Arm predicted mass (right) 0.2 0.8 1.6 -0.7 -1.2 0.0 -1.2 0.7 0.6 -1.0 0.9 1.1 1.2 1.0 0.6 0.5 1.0
Pulse rate, automated reading 0.8 2.7 5.5 1.8 1.6 0.0 0.8 -2.0 1.6 1.4 -1.7 -2.0 -2.3 -1.2 -2.1 -0.3 -2.1
Alcohol intake frequency. 0.0 0.1 0.7 -0.2 0.1 0.0 -0.3 -0.1 -0.8 0.1 -0.4 -0.2 -0.2 0.1 0.2 -0.5 -0.2
Comparative height size at age 10 0.1 0.3 1.0 -0.3 -1.0 0.0 -0.7 0.4 0.6 -0.1 0.4 0.6 0.9 0.5 0.0 0.5 0.4
Number of full sisters 0.3 0.3 0.9 -0.1 -0.7 0.0 -1.0 0.3 1.0 -0.7 0.6 0.6 0.4 0.5 0.4 0.4 0.7
Suffer from ‘nerves’ 0.4 0.6 2.3 -0.3 -0.9 0.0 -0.9 0.6 1.5 -0.7 0.8 0.7 0.5 0.5 0.4 0.7 0.9
Overall health rating 0.3 0.6 2.4 1.2 1.0 0.0 0.4 -0.9 0.6 0.1 -0.4 -0.5 -0.8 -0.3 -0.9 -1.6 -0.2
Chest pain or discomfort 0.1 0.2 0.6 0.6 0.4 0.0 -0.1 -0.5 -0.1 -0.1 -0.4 -0.4 -0.8 -0.6 -0.5 -0.1 -0.4
Had major operations 0.3 0.3 1.4 0.0 0.3 0.0 -0.7 -0.4 1.0 -0.6 -0.3 -0.3 -0.4 0.5 -0.5 1.2 -0.4
Age at last live birth 0.5 0.8 1.7 -1.2 -0.5 0.0 -0.2 0.9 -0.5 -0.8 1.0 1.1 1.2 0.6 1.3 0.3 1.2
Family relationship satisfaction 0.4 0.5 2.2 0.5 0.7 0.0 1.2 -0.2 -1.1 0.6 -0.3 -0.3 -0.1 -0.7 -0.1 -1.5 -0.1
Leg pain on walking 0.2 0.3 1.1 0.7 -0.1 0.0 0.5 -0.3 0.5 1.0 -0.1 -0.3 -0.2 -0.8 -0.3 -1.0 -0.2
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 2.8 -0.5 -0.8 0.0 -1.7 0.0 -1.1 -0.5 -0.2 0.2 0.2 0.5 0.1 -0.2 -0.1
Commuting to job workplace: Car/motor vehicle 1.1 1.3 2.4 -1.3 -1.0 0.0 -1.5 1.0 1.4 -1.1 1.2 1.1 1.0 0.8 1.2 1.6 0.9
Illness, injury, bereavement, stress in last 2 years 0.4 0.4 2.2 0.1 -0.5 0.0 0.3 -0.3 -1.5 0.7 -0.7 -0.5 -0.3 -1.2 -0.4 -0.0 -0.7
Medication: Aspirin 1.1 1.5 3.6 1.3 1.9 0.0 1.6 -1.1 -0.3 0.8 -1.1 -1.1 -1.3 -1.4 -1.1 -1.6 -0.9
Supplements: Vitamin C 2.7 3.2 5.4 -1.8 -1.9 0.0 -1.1 1.7 1.7 -1.8 2.2 2.1 2.3 1.3 2.0 1.4 2.3
Knee pain experienced in last month 0.4 0.7 1.6 0.7 0.7 0.0 0.2 -1.0 0.1 0.6 -1.2 -1.0 -1.2 -0.5 -1.1 0.0 -1.3
Hypertension (Self-reported) 0.3 0.9 2.6 -0.8 -0.8 0.0 -1.3 0.5 1.5 -1.6 0.6 0.5 0.0 0.7 0.3 1.6 0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.2 2.6 5.5 1.6 0.6 0.0 0.8 -2.2 -1.6 1.2 -2.3 -1.9 -1.9 -0.5 -2.0 -1.9 -2.0
Illnesses of father: Heart disease 0.2 0.3 0.9 0.5 0.7 0.0 0.7 0.0 -0.7 0.7 0.3 0.1 0.4 -1.0 0.2 -1.0 0.3
Illnesses of siblings: Diabetes 2.1 2.6 4.2 1.7 1.6 0.0 2.0 -1.5 -0.8 1.9 -1.8 -1.8 -1.7 -1.6 -1.7 -1.2 -1.7
Smoking status: Previous 0.1 0.2 2.1 0.5 1.4 0.0 0.4 -0.3 0.2 0.3 0.1 -0.1 -0.2 -0.2 -0.4 0.1 0.1
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 1.4 -1.1 -0.8 0.0 -0.4 0.8 0.1 -0.7 0.7 1.1 1.2 0.5 0.9 0.7 0.8
Whole body fat-free mass 0.2 1.3 2.2 -1.0 -1.4 0.0 -1.5 0.9 0.8 -1.2 1.2 1.4 1.4 1.4 1.0 0.6 1.3
Leg fat-free mass (right) 0.2 1.3 2.4 -1.1 -1.1 0.0 -1.4 1.1 0.2 -1.1 1.3 1.5 1.5 1.4 1.2 0.4 1.3
Arm fat percentage (left) 0.1 0.3 1.7 0.5 0.5 0.0 -0.2 -0.3 -0.4 -0.0 -0.2 -0.1 -0.2 -1.3 -0.2 -1.1 0.2
Average weekly red wine intake 1.3 1.9 5.7 -0.8 -1.2 0.0 -1.5 1.1 2.4 -1.7 1.3 1.3 0.9 0.6 0.8 2.4 1.4
Handedness (chirality/laterality): Left-handed 1.7 2.1 5.0 -0.8 -0.8 0.0 -1.6 1.1 2.2 -1.7 1.7 1.4 1.1 2.0 1.0 1.7 1.6
Mood swings 0.2 0.3 2.3 0.3 0.4 0.0 -0.5 -0.1 1.5 -0.1 0.4 0.2 0.0 -0.2 0.1 -0.9 0.7
Loneliness, isolation 0.2 0.2 1.0 0.7 1.0 0.0 0.4 -0.3 -0.2 0.9 0.1 -0.2 -0.0 -0.2 -0.2 -0.9 -0.0
Long-standing illness, disability or infirmity 0.2 0.4 3.1 0.5 0.5 0.0 -0.6 -0.4 1.8 -0.5 0.4 0.2 -0.2 -0.4 -0.3 -0.3 0.6
Ever had bowel cancer screening 0.1 0.1 0.3 0.0 -0.0 0.0 -0.4 0.0 -0.6 -0.1 0.2 0.3 0.4 0.0 0.1 -0.3 0.3
Diabetes diagnosed by doctor 0.6 1.0 3.3 0.9 1.8 0.0 1.2 -1.0 0.5 0.6 -0.8 -1.0 -1.3 -0.9 -1.0 -0.5 -0.7
Ever had stillbirth, spontaneous miscarriage or termination 2.5 2.7 4.5 2.1 1.6 0.0 2.1 -1.8 0.2 1.4 -1.5 -1.7 -1.7 -1.6 -1.9 -2.1 -1.5
Friendships satisfaction 0.3 0.4 1.9 0.4 0.1 0.0 1.0 0.5 -0.9 0.1 0.5 0.3 0.5 -0.7 0.3 -1.4 0.6
Qualifications: nursing, teaching 0.3 0.4 2.0 -0.2 -0.2 0.0 1.1 0.2 -0.5 0.2 0.2 0.3 0.6 -0.8 0.5 -1.4 0.7
Commuting to job workplace: Walk 0.3 0.3 3.2 -0.1 0.2 0.0 0.2 0.0 -1.8 -0.4 -0.4 -0.1 -0.1 0.1 -0.1 -0.7 -0.2
Eye problems/disorders: Cataract 0.2 0.2 0.6 -0.5 0.0 0.0 0.7 0.5 -0.3 -0.3 0.5 0.4 0.7 0.7 0.6 0.1 0.4
Mouth/teeth dental problems: Mouth ulcers 0.5 0.7 2.8 0.5 1.5 0.0 0.5 -0.5 -1.7 0.5 -0.5 -0.6 -0.6 -0.9 -0.6 -1.1 -0.6
Medication for cholesterol 0.3 0.5 2.6 0.1 0.7 0.0 1.1 0.2 -1.6 0.8 -0.0 -0.1 0.3 -0.4 0.2 -1.0 0.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 3.9 4.6 8.9 2.3 2.3 0.0 2.2 -2.2 -0.5 1.6 -2.5 -2.4 -2.5 -3.0 -2.5 -1.7 -2.2
Back pain experienced in last month 0.2 0.3 1.9 -0.1 -0.3 0.0 -1.4 0.4 0.9 -0.5 0.4 0.4 0.0 0.6 0.1 0.7 0.3
Mineral and other dietary supplements 0.5 0.6 1.6 0.7 0.3 0.0 0.7 -1.1 -0.4 0.3 -1.1 -1.0 -1.2 -0.5 -0.9 -0.8 -0.9
Breast cancer (self-reported) 0.6 0.7 1.2 -0.6 -1.0 0.0 -0.9 0.8 1.1 -1.0 0.8 0.9 0.9 -0.5 0.6 0.6 1.1
Asthma (self-reported) 0.3 0.6 1.8 0.6 1.0 0.0 0.6 -0.3 -0.9 1.2 -0.4 -0.6 -0.6 -0.9 -0.3 -1.3 -0.7
Osteoporosis (self-reported) 0.2 0.2 2.0 0.4 0.5 0.0 -0.1 -0.3 1.4 0.1 -0.1 -0.3 -0.4 -0.3 -0.3 0.1 -0.1
Osteoarthritis (self-reported) 0.5 0.6 1.5 1.2 1.1 0.0 0.1 -1.0 0.5 0.5 -0.7 -0.9 -1.0 -0.3 -1.2 -0.2 -0.9
Medication: Aspirin 1.5 1.9 5.2 1.4 2.3 0.0 1.7 -1.2 -0.9 1.0 -1.2 -1.3 -1.4 -1.6 -1.2 -1.8 -1.0
Medication: Gliclazide 0.1 0.1 0.7 -0.2 0.5 0.0 0.1 -0.0 -0.8 0.5 -0.2 -0.1 0.0 -0.1 0.1 0.1 -0.3
Illnesses of father: None of the above (group 1) 0.5 0.6 1.5 0.6 0.7 0.0 0.4 -0.9 -0.4 1.1 -1.1 -1.0 -1.0 -0.0 -1.0 -0.4 -1.2
Smoking status: Current 0.2 0.3 1.0 0.5 0.5 0.0 0.5 0.3 -0.7 0.2 0.5 0.3 0.3 -0.7 0.1 -1.0 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 1.3 0.9 0.3 0.0 0.8 -0.9 0.3 0.7 -1.0 -1.1 -1.1 -0.4 -0.9 0.4 -1.1
Whole body water mass 0.3 1.6 2.8 -1.1 -1.5 0.0 -1.7 1.1 0.8 -1.3 1.4 1.6 1.6 1.5 1.1 0.7 1.4
Leg predicted mass (right) 0.2 1.3 2.2 -1.1 -1.1 0.0 -1.4 1.0 0.2 -1.1 1.3 1.4 1.5 1.4 1.2 0.4 1.3
Arm fat mass (left) 0.1 0.2 0.8 -0.1 -0.3 0.0 -0.9 0.2 0.0 -0.6 0.5 0.6 0.6 -0.4 0.4 -0.5 0.8
Number of self-reported non-cancer illnesses 1.6 2.8 6.2 1.9 1.6 0.0 1.0 -2.0 0.5 1.3 -1.8 -2.1 -2.5 -1.9 -2.2 -0.7 -1.9
Average weekly champagne plus white wine intake 0.7 1.0 2.9 -1.1 -1.1 0.0 0.0 1.3 -0.1 -0.3 1.3 1.3 1.7 -0.2 1.4 -0.1 1.4
Miserableness 0.1 0.2 1.1 0.4 0.6 0.0 0.3 -0.3 -0.2 -0.0 -0.1 -0.2 -0.4 -0.8 -0.2 -1.0 0.1
Guilty feelings 1.0 1.4 2.2 -1.3 -1.5 0.0 -1.3 1.1 -0.1 -1.5 1.2 1.4 1.4 1.4 1.3 0.1 1.4
Wears glasses or contact lenses 1.2 1.3 2.4 1.2 1.6 0.0 0.8 -1.2 -0.5 1.2 -1.3 -1.4 -1.5 -1.0 -1.3 -0.6 -1.5
Ever taken oral contraceptive pill 0.2 0.2 0.9 0.2 0.1 0.0 -0.1 0.1 0.0 -0.5 0.6 0.5 0.5 -0.1 0.1 -0.6 0.9
Hearing aid user 0.4 0.4 1.1 0.7 0.7 0.0 0.6 -0.7 -0.2 0.7 -0.8 -0.7 -0.6 -0.4 -1.0 -0.1 -0.9
Mother’s age at death 0.2 0.2 0.6 0.4 0.2 0.0 -0.4 -0.6 0.6 -0.3 -0.4 -0.4 -0.6 -0.2 -0.8 0.8 -0.4
Financial situation satisfaction 0.4 0.5 1.3 -0.7 -1.0 0.0 -0.8 0.6 -0.1 -0.7 0.8 0.7 0.7 1.1 0.6 0.6 0.6
Tinnitus: Yes, now most or all of the time 0.2 0.3 0.6 0.7 -0.8 0.0 -0.1 -0.7 -0.6 -0.3 -0.6 -0.3 -0.4 -0.3 -0.6 -0.7 -0.2
Commuting to job workplace: Public transport 2.9 3.5 6.0 2.1 1.4 0.0 2.2 -1.9 -0.4 2.5 -2.0 -2.0 -1.8 -2.1 -2.0 -2.2 -1.8
Eye problems/disorders: Glaucoma 0.3 0.4 1.2 1.1 0.3 0.0 0.3 -0.7 0.0 0.4 -0.5 -0.5 -0.7 -1.0 -1.0 -0.6 -0.3
Medication: Blood pressure 0.1 0.2 0.9 -0.3 -0.3 0.0 -0.4 -0.3 0.0 -0.3 -0.5 -0.4 -0.5 0.3 -0.2 1.0 -0.6
Pain type(s) experienced in last month: Hip pain 0.1 0.2 1.0 0.7 0.3 0.0 0.2 -0.1 -0.2 0.6 0.0 -0.0 -0.0 -0.8 -0.2 -1.0 0.2
Supplements: Fish oil (including cod liver oil) 0.4 0.5 0.9 -0.6 -0.5 0.0 -0.6 0.9 0.9 -0.4 0.9 0.8 1.0 0.8 0.7 0.6 0.7
High cholesterol (Self-reported) 1.8 3.1 5.9 1.8 1.9 0.0 1.1 -2.1 -0.0 1.2 -2.1 -2.1 -2.4 -2.1 -2.3 -0.4 -2.1
Medication: Bendroflumethiazide 0.4 0.7 1.1 0.8 1.0 0.0 0.8 -0.8 -0.6 0.5 -0.9 -1.0 -1.0 -1.0 -1.0 -0.3 -1.0
Medication: Paracetamol 0.5 0.8 2.0 -0.5 -0.2 0.0 -1.4 0.7 1.3 -1.3 1.0 1.0 0.7 0.5 0.6 0.5 1.1
Medication: Lisinopril 0.0 0.0 0.2 0.2 -0.3 0.0 0.1 -0.2 0.5 -0.0 0.0 -0.1 -0.1 0.2 -0.1 -0.1 -0.0
Medication: Atorvastatin 0.5 0.7 3.1 0.2 1.3 0.0 1.5 -0.2 -1.8 0.9 -0.5 -0.5 -0.3 -0.5 -0.4 -0.2 -0.7
Illnesses of father: High blood pressure 3.8 4.6 7.3 -2.5 -2.0 0.0 -2.1 2.5 1.0 -2.5 2.3 2.4 2.3 1.8 2.3 2.7 2.3
Alcohol drinker status: Never 0.2 0.3 0.7 0.2 0.4 0.0 0.0 -0.6 0.3 0.6 -0.7 -0.7 -0.8 -0.9 -0.2 -0.2 -0.7
Ever smoked 0.1 0.1 1.0 0.5 1.0 0.0 0.2 0.0 0.0 -0.1 0.3 0.2 0.2 -0.4 -0.2 -0.3 0.6
Basal metabolic rate 0.2 0.9 1.9 -0.8 -1.1 0.0 -1.4 0.8 0.7 -1.1 1.0 1.2 1.2 1.0 0.8 0.4 1.1
Leg fat percentage (left) 0.1 0.5 2.1 0.9 0.7 0.0 -0.4 -0.8 0.1 0.1 -0.5 -0.4 -0.6 -1.5 -0.7 -1.1 -0.1
Arm fat-free mass (left) 0.3 1.3 2.3 -0.9 -1.5 0.0 -1.5 0.9 0.8 -1.2 1.3 1.4 1.5 1.1 1.0 0.5 1.4
Number of operations (self-reported) 0.5 0.7 2.0 -0.6 -0.5 0.0 -0.7 0.6 1.4 -1.3 0.6 0.5 0.3 1.3 0.3 1.4 0.3
Average weekly beer plus cider intake 1.4 2.0 4.1 1.5 0.9 0.0 0.6 -1.6 0.4 1.2 -1.8 -1.7 -2.0 -1.7 -1.8 -0.9 -1.8
Irritability 1.0 1.6 3.8 -0.9 -1.8 0.0 -0.9 1.3 1.1 -1.0 1.6 1.5 1.6 0.1 1.6 0.2 1.9
Risk taking 0.4 0.6 2.6 -0.8 -0.4 0.0 -1.1 0.5 -0.0 -1.6 0.5 0.8 0.7 0.7 0.6 0.6 0.7
Ever had prostate specific antigen (PSA) test 1.9 2.2 4.6 1.7 0.9 0.0 0.9 -2.1 0.8 1.4 -1.7 -1.8 -2.0 -0.4 -1.9 -1.1 -1.8
Fractured/broken bones in last 5 years 0.3 0.4 1.1 0.8 0.7 0.0 0.1 -0.7 -0.1 0.3 -0.7 -0.7 -0.9 0.2 -1.0 -0.5 -0.9
Age started oral contraceptive pill 0.5 0.6 1.5 -1.1 -0.3 0.0 0.7 1.1 -0.5 -0.7 0.8 0.8 1.2 0.4 1.1 0.7 0.8
Diastolic blood pressure, automated reading 0.5 1.6 4.2 0.6 0.2 0.0 -0.5 -0.9 1.7 -0.1 -1.3 -1.4 -2.0 -0.3 -1.7 2.0 -1.8
Ever depressed for a whole week 1.3 1.7 3.0 -1.2 -1.5 0.0 -1.2 1.1 0.1 -1.3 1.5 1.6 1.7 1.5 1.6 0.1 1.7
Unable to work because of sickness or disability 0.8 1.0 3.0 1.6 0.8 0.0 0.4 -1.1 1.2 0.6 -0.4 -0.8 -1.1 -1.7 -1.1 -1.1 -0.1
Commuting to job workplace: Cycle 0.3 0.3 0.8 0.4 0.5 0.0 0.8 -0.4 -0.9 0.8 -0.5 -0.5 -0.4 0.0 -0.4 -0.7 -0.6
Myopia 0.5 0.7 1.4 -0.9 -0.0 0.0 -1.2 1.0 -0.3 -0.6 0.9 1.0 0.9 0.5 1.1 -0.4 1.1
Vascular/heart problems diagnosed by doctor 0.2 0.6 2.1 0.5 0.6 0.0 1.2 -0.1 -1.5 1.3 -0.3 -0.2 0.3 -0.7 -0.0 -1.3 -0.3
Cholesterol lowering medication 1.3 1.9 3.4 1.5 1.1 0.0 1.2 -1.8 -0.4 0.9 -1.8 -1.6 -1.6 -1.4 -1.6 -1.4 -1.5
Medication: Omeprazole (e.g. Zanprol) 0.9 1.1 2.4 0.6 1.4 0.0 0.6 -1.0 -1.6 0.9 -1.3 -1.1 -1.0 -1.0 -1.0 -1.2 -1.3
Pain experienced in last month 0.1 0.1 0.6 -0.2 0.2 0.0 0.6 0.1 -0.6 0.2 0.2 0.2 0.5 -0.1 0.4 -0.8 0.3
Supplements: Calcium 0.4 0.4 1.2 -0.2 -0.7 0.0 -0.6 0.8 0.4 -0.2 0.9 0.8 1.1 -0.4 0.6 -0.1 1.0
Basal cell carcinoma (self-reported) 0.2 0.2 0.8 0.4 0.0 0.0 -0.9 -0.8 0.5 -0.2 -0.3 -0.3 -0.5 0.6 -0.4 -0.6 -0.2
Heart attack/myocardial infarction (self-reported) 0.4 0.5 1.5 1.0 0.5 0.0 0.1 -1.1 1.2 0.3 -0.5 -0.6 -0.8 -0.8 -0.9 -0.7 -0.3
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 1.5 0.5 0.9 0.0 1.2 -0.9 1.2 0.8 -0.5 -0.8 -0.6 -0.6 -0.6 -0.4 -0.8
Heart disease (siblings) 2.3 2.8 5.7 2.2 1.4 0.0 1.8 -2.3 -0.7 1.5 -1.9 -1.7 -1.7 -1.0 -1.9 -2.4 -1.4
Alcohol drinker status: Previous 0.2 0.2 0.7 0.4 0.5 0.0 -0.3 -0.4 -0.4 -0.8 -0.4 -0.2 -0.6 0.6 -0.4 0.0 -0.1
Pack years of smoking 0.2 0.3 0.8 -0.6 0.2 0.0 0.5 0.9 0.1 -0.4 0.8 0.7 0.8 0.2 0.8 0.2 0.7
Impedance of whole body 0.4 2.0 3.4 1.3 1.3 0.0 1.3 -1.6 0.0 0.9 -1.8 -1.8 -1.8 -1.7 -1.8 -0.1 -1.8
Leg fat mass (left) 0.0 0.2 0.8 0.4 0.1 0.0 -0.9 -0.4 0.1 -0.3 -0.0 0.1 -0.0 -0.6 -0.2 -0.7 0.3
Arm predicted mass (left) 0.3 1.3 2.4 -0.9 -1.5 0.0 -1.5 0.9 0.7 -1.1 1.2 1.4 1.5 1.2 1.0 0.6 1.4