Hub : Genes

KCNK17

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.1371	0.0325	2.2e-09	0.075	0.078	0.087	NA	0.077	2.7e-11	1.1e-11	5.0e-13	NA	1.1e-11
2	TCGA	Cervical Squamous Cell Carcinoma	0.2210	0.0880	3.8e-03	0.001	0.029	0.066	NA	0.016	2.9e-01	1.3e-02	3.6e-04	NA	5.3e-02
3	TCGA	Head and Neck Squamous Cell Carcinoma	0.2059	0.0555	3.2e-06	0.005	0.035	0.013	NA	0.000	9.1e-02	8.2e-05	1.3e-02	NA	3.1e-01
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0647	0.0288	7.3e-04	0.044	0.024	0.038	NA	0.038	8.6e-06	9.3e-04	3.7e-05	NA	4.0e-05
5	TCGA	Brain Lower Grade Glioma	0.0470	0.0262	5.7e-03	-0.001	0.005	0.008	NA	0.001	4.3e-01	8.4e-02	4.0e-02	NA	2.2e-01
6	TCGA	Lung Adenocarcinoma	0.0432	0.0207	3.3e-03	0.009	0.005	0.000	NA	0.001	2.8e-02	6.6e-02	3.1e-01	NA	2.3e-01
7	TCGA	Lung Squamous Cell Carcinoma	0.0526	0.0269	7.3e-03	-0.002	0.020	0.007	NA	0.000	5.8e-01	2.3e-03	4.6e-02	NA	3.4e-01
8	TCGA	Ovarian Serous Cystadenocarcinoma	0.2480	0.0660	2.1e-10	0.164	0.154	0.181	NA	0.192	3.0e-11	1.3e-10	2.7e-12	NA	5.0e-13
9	TCGA	Pancreatic Adenocarcinoma	0.1660	0.0680	1.8e-03	0.118	0.070	0.048	NA	0.056	1.2e-05	7.1e-04	4.3e-03	NA	2.2e-03
10	TCGA	Pheochromocytoma and Paraganglioma	0.0930	0.0460	8.2e-03	0.057	0.054	0.017	NA	0.053	2.7e-03	3.5e-03	6.6e-02	NA	3.8e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	0.6	1.0	3.4	1.8	0.6	1.3	0.9	0.3	0.2	0.9	-0.5	-1.1	1.1
Bipolar Disorder or Schizophrenia	0.2	0.4	0.9	-0.3	0.9	0.9	-0.9	0.3	0.5	0.3	0.9	-0.2	0.1
Depressed Affect (Nagel 2018)	1.1	2.3	5.8	1.8	-1.8	-0.9	2.4	-1.6	-1.2	-1.3	-1.6	-1.2	0.4
Depression (Nagel 2018)	0.5	0.7	2.6	1.6	0.9	0.6	1.3	-0.4	-0.0	1.2	-0.2	-0.6	0.3
Intelligence (Savage-Jansen 2018)	0.4	1.3	4.2	-1.5	0.2	-0.1	-0.7	0.2	2.1	0.1	1.8	0.9	-1.2
Neuroticism (Nagel 2018)	0.9	2.2	4.8	1.0	-2.2	-1.4	1.8	-2.1	-1.2	-0.9	-1.6	-1.1	0.4
Schizophrenia (2018)	0.5	1.1	3.5	-1.9	0.4	-0.0	-1.9	0.0	0.6	-0.4	1.6	0.6	-0.8
Schizophrenia vs Biploar Disorder	0.6	0.8	1.8	-0.3	-1.0	-0.3	-0.6	-0.8	1.3	-1.1	0.6	0.7	-1.2
Worry (Nagel 2018)	0.5	1.1	3.1	0.3	-1.8	-1.4	1.4	-1.0	-0.3	-0.7	-1.3	-1.0	0.3
Alzheimer’s Disease (in mother)	2.0	2.3	6.2	-1.2	0.4	1.7	-2.3	-0.7	1.1	1.1	2.5	1.8	-1.1
Alzheimer’s Disease (in father)	0.6	0.6	3.1	-1.8	0.8	0.3	-0.7	-0.9	-0.7	0.3	0.5	-0.2	0.3
Alzheimer’s Disease (including proxy)	1.1	1.6	4.9	-1.9	0.1	1.2	-2.2	-1.0	0.5	0.3	1.6	1.2	-0.8
Crohns Disease (2017)	0.3	0.7	2.6	-0.1	0.1	-1.0	-0.5	-0.5	1.6	-0.5	0.9	0.3	-1.2
Irritable Bowel Disease (IBD)	0.3	0.8	4.2	0.4	-0.8	-2.1	0.4	-1.0	0.1	-0.9	-0.3	-0.6	-0.6
Ulcerative Colitis (UC)	0.8	1.5	4.0	0.6	-1.0	-2.0	1.1	-1.1	-1.5	-0.6	-1.1	-1.5	0.5
Major Depression (MDD)	1.5	1.9	5.6	-0.1	-1.6	-1.6	-0.1	0.3	-1.1	-2.4	0.3	-1.1	-2.3
Reaction Time	1.0	1.9	5.7	1.5	0.1	-0.1	1.3	-1.4	-2.4	1.2	-1.4	-1.1	1.7
Verbal and Numeric Reasoning (VNR)	0.4	1.0	4.5	0.2	1.5	1.1	0.2	0.4	2.1	1.0	0.4	0.0	0.2
Breast Cancer	0.1	0.3	1.0	0.3	-0.6	-0.3	0.8	0.3	-0.6	-0.4	-1.0	-0.5	-0.2
Ovarian Cancer	0.3	0.4	2.3	0.2	0.7	-0.2	-0.0	-0.1	1.5	0.7	-0.3	-0.1	0.5
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.1	0.2	0.7	0.0	0.1	0.1	-0.5	-0.7	0.6	-0.8	0.2	0.4	0.0
Bipolar Disorder (2011)	0.3	0.3	1.2	0.6	-1.1	-0.6	0.2	-0.3	0.5	0.5	-0.3	-0.4	0.2
Body Mass Index (BMI) (2010)	1.3	1.8	5.6	2.1	2.1	0.7	0.3	0.3	-2.4	1.5	0.1	-0.2	0.9
Coronary Artery Disease (CAD)	0.6	0.7	2.2	-0.4	-0.9	0.8	-0.3	0.6	1.5	1.1	0.7	0.6	0.6
Crohns Disease (2012)	0.6	1.0	3.0	-0.9	-0.4	-1.3	-0.8	-0.3	1.3	-1.7	0.4	-0.1	-1.2
Mean Putamen Volume	1.8	2.0	4.8	-1.1	-0.6	0.6	-1.3	0.4	2.0	1.0	2.1	2.2	-1.5
Fasting Glucose	0.7	0.8	4.1	-1.3	-2.0	-1.0	0.5	0.2	0.1	-0.1	-0.6	0.8	0.4
HbA1C	0.6	0.7	2.2	0.4	-0.7	-0.3	1.2	-0.4	-1.2	0.5	-1.5	-0.3	0.9
HDL Cholesterol	0.7	1.2	4.0	0.3	-2.0	1.9	-0.1	-0.1	1.8	-0.6	0.5	0.3	-0.6
LDL Cholesterol	0.6	1.0	2.9	-0.8	0.4	-0.3	-1.2	1.1	1.7	1.1	0.8	0.9	-0.5
Lupus	1.6	2.4	14.1	-0.3	-3.8	-1.9	-0.0	-0.8	-0.9	-1.7	-0.1	0.9	-1.2
Neuroticism (2016)	0.5	0.7	2.9	0.3	0.0	-0.4	1.0	0.0	-0.6	-0.7	-1.4	-1.7	0.6
Primary Biliary Cirrhosis	1.2	1.8	7.2	-2.7	0.7	0.2	-1.3	0.8	0.9	-0.6	1.5	1.6	-1.2
Rheumatoid Arthritis	0.7	0.9	5.7	-2.4	0.6	0.8	-1.1	-0.3	0.5	-0.1	1.0	0.2	-0.3
Schizophrenia (2014)	0.3	0.6	1.8	-1.3	0.3	0.4	-1.3	-0.7	0.5	-0.0	1.1	0.7	-0.4
Triglycerides	0.7	1.1	2.5	-1.6	0.9	-1.6	-0.7	0.0	-1.1	1.4	0.7	1.1	0.2
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.7	-0.9	-1.1	-1.6	-0.0	1.1	-0.9	-0.8	-0.4	0.2	-0.8
Ulcerative Colitis	0.8	1.1	5.3	-0.4	-2.3	-1.5	-0.2	-0.9	-0.6	-1.3	-0.6	-0.4	-0.0
Blood Eosinophil Count	0.1	0.7	3.3	-0.0	-0.5	0.8	1.0	-1.8	-0.6	1.0	0.4	-0.2	0.5
Blood Platelet Count	0.4	4.8	17.8	-4.2	-1.3	0.3	-2.0	0.2	2.9	-0.0	2.4	2.6	-1.8
Blood Red Count	0.1	1.4	2.7	1.4	0.7	1.0	0.2	1.5	1.6	-0.9	1.6	0.3	-1.4
Blood White Count	0.3	1.9	5.9	-0.3	1.5	1.2	-0.1	2.4	1.8	-0.6	1.5	0.3	-1.8
Heel T-Score	0.4	3.4	12.7	3.6	-0.6	2.1	2.5	-0.8	1.0	0.5	-1.5	-1.9	1.6
BMI	0.6	3.8	13.0	3.3	1.8	-0.9	1.5	-0.3	-3.6	1.0	-0.9	-2.1	0.9
Height	0.2	3.6	9.7	-1.2	0.1	-2.5	3.1	-2.5	-1.8	-0.6	-1.6	0.4	2.6
Waist Hip Ratio (WHR)	1.2	5.3	11.0	-3.0	-3.3	-1.7	-1.9	0.9	2.6	-1.3	2.2	1.1	-3.3
Systolic Blood Pressure	0.7	3.4	10.3	-2.1	1.7	1.7	0.3	1.6	3.2	2.9	0.4	1.2	1.3
Smoking Status	0.2	0.5	1.6	1.0	0.3	1.3	1.2	-0.0	0.1	-0.5	0.2	-0.8	0.1
Allergy or Eczema	0.2	0.6	1.9	-0.2	-1.1	-1.4	0.3	0.3	-0.5	-1.2	-0.2	-0.3	-1.0
Cardiovascular Disease	2.1	6.8	11.4	-3.3	1.7	0.0	-2.6	2.7	2.5	3.3	3.1	3.4	-1.7
Hypothyroidism (self reported)	0.7	1.7	4.7	-1.6	-0.1	-0.6	-2.2	-1.2	0.0	0.9	1.5	2.1	-0.6
Respiratory disease	0.4	0.8	5.0	0.0	-1.1	-0.7	-0.3	-0.7	-2.2	-0.3	-0.1	-0.7	-0.4
Type 2 Diabetes (T2D) (2018)	2.0	3.8	22.3	-2.5	-4.7	-2.1	-0.1	0.3	-0.0	-1.2	0.1	1.5	-1.2
Lung FEV1/FVC ratio	0.3	1.3	5.0	-0.7	-0.4	-1.5	-1.4	0.5	0.9	-0.8	1.1	0.9	-2.2
Lung FVC	0.3	1.5	3.8	0.6	1.8	1.2	1.6	0.7	-0.6	1.2	-1.3	-0.1	2.0
Neuroticism	0.9	2.1	8.0	0.7	-2.8	-2.0	1.4	-1.3	-1.3	-1.0	-1.3	-1.0	-0.4
Chronotype (morning person)	0.5	1.2	5.3	1.3	0.8	0.8	0.1	1.3	0.5	-2.3	0.6	0.2	-1.2
Hair Pigment	0.0	0.9	3.2	0.1	-0.4	-0.6	0.5	1.2	1.8	0.1	1.1	0.7	-1.2
Tanning	0.1	0.9	5.3	0.5	-1.0	2.3	-0.3	0.9	-0.5	-0.5	-0.2	0.4	0.6
Hand grip strength (left)	0.2	0.5	2.6	-1.0	0.5	0.3	-0.4	0.9	0.4	0.5	0.4	1.6	-0.0
Number of treatments/medications taken	1.2	2.2	8.5	-2.9	-1.1	-1.6	-1.2	-0.4	0.9	0.2	1.7	1.1	-1.9
Average weekly spirits intake	1.4	1.7	5.9	1.1	1.5	-1.0	1.1	0.7	-1.4	0.6	-1.5	-2.4	0.8
Sensitivity / hurt feelings	0.5	0.9	2.3	0.2	-1.5	-0.9	-0.6	-1.3	-1.5	0.3	-0.1	0.0	-0.9
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.7	1.3	0.6	0.3	1.0	-0.3	0.2	1.0	0.1	-0.7	0.0
Hearing difficulty/problems: Yes	0.3	0.5	1.0	-1.0	0.9	-0.4	-1.0	0.1	-0.7	-0.2	0.8	0.1	-0.6
Relative age of first facial hair	0.7	1.4	4.0	0.9	1.6	1.3	-0.4	-0.9	0.6	2.0	-0.4	-0.2	1.9
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.3	-0.5	1.1	0.6	0.4	-0.2	-0.4	0.3	0.1	0.6	0.6
Ever used hormone-replacement therapy (HRT)	0.5	0.6	3.1	0.3	0.0	0.1	-0.9	-0.2	-0.0	-1.7	0.3	-0.9	-0.9
Ever had hysterectomy (womb removed)	0.8	0.9	2.9	-0.4	-1.2	-1.2	-0.6	-0.1	0.7	-1.7	-0.3	-0.9	-1.1
Systolic blood pressure, automated reading	0.4	1.2	3.6	-1.0	1.8	0.7	0.4	0.6	0.8	1.9	-0.4	-0.2	1.6
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	8.5	-0.3	0.2	1.4	0.5	2.9	1.7	1.6	1.0	2.1	0.0
Angina	3.6	4.8	12.1	-3.5	1.1	0.2	-2.4	0.9	1.3	1.9	3.3	2.9	-1.8
Medication for hormone replacement therapy	0.6	0.7	2.1	-0.4	1.1	0.1	-0.5	1.4	0.5	-1.0	0.4	-0.2	-1.4
Vitamin and mineral supplements	0.2	0.3	1.5	-0.2	-0.6	-0.6	-0.3	-0.5	0.3	-1.2	0.2	0.1	-0.8
Supplements: Zinc	0.4	0.4	1.1	0.3	0.3	0.6	-0.3	-1.0	-0.8	0.9	0.0	-0.0	1.1
Medication: Co-codamol	0.9	1.1	2.5	-0.2	-0.1	0.9	-1.2	-1.0	1.6	1.3	1.6	0.7	-0.7
Medication: Metformin	2.2	3.1	8.8	-2.2	-3.0	-2.2	-0.5	2.0	0.8	-1.2	0.8	1.3	-2.1
Diabetes (father)	0.9	1.1	3.5	-0.0	-1.9	0.5	0.2	0.5	1.5	-1.5	0.1	1.1	-1.1
Diabetes (mother)	2.0	2.5	7.2	-1.0	-2.7	-1.2	-1.2	1.1	1.3	-2.2	0.3	0.3	-2.4
Severe depression (siblings)	0.8	0.9	2.5	1.2	0.3	-0.5	1.3	-0.3	1.3	-0.9	-0.6	-1.6	-0.5
Pack years adult smoking proportion	0.4	0.6	2.1	-0.4	1.4	0.8	0.2	1.0	-0.7	0.2	-0.8	-0.7	0.8
Impedance of leg (right)	2.3	11.2	42.7	-3.7	-0.3	1.7	-3.0	3.5	6.5	-0.2	2.9	3.6	-3.2
Leg fat-free mass (left)	1.0	5.1	19.3	2.5	0.0	-1.0	2.9	-2.1	-4.4	0.3	-1.7	-1.7	2.4
Trunk fat percentage	0.1	0.4	1.4	0.9	0.6	0.4	1.2	0.7	-0.5	-0.3	-0.1	-0.0	0.3
Hand grip strength (right)	1.0	2.8	5.3	-1.9	1.2	0.7	-1.7	2.0	1.8	1.0	2.1	2.3	-1.3
Townsend deprivation index at recruitment	0.2	0.2	0.7	-0.0	-0.9	-0.2	-0.6	0.2	0.2	-0.3	0.8	0.1	-0.6
Current tobacco smoking	0.2	0.4	1.2	0.3	-0.7	0.9	0.8	-0.2	-0.3	-0.5	-0.0	-1.1	-0.1
Average weekly fortified wine intake	1.8	2.1	6.4	0.6	-1.3	-1.5	0.3	-1.4	-2.5	-0.7	-1.8	-2.1	0.8
Maternal smoking around birth	1.8	2.7	8.2	-1.3	0.0	1.2	-1.3	0.3	1.6	2.2	2.9	2.4	-0.7
Fed-up feelings	2.0	3.6	7.6	1.3	-2.1	-0.9	2.8	-2.0	-2.3	-0.3	-2.5	-1.8	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	3.8	0.1	0.9	0.6	1.3	-0.3	-1.0	2.0	-0.7	-0.3	1.4
Relative age voice broke	0.3	0.5	1.6	1.3	1.1	0.1	-0.3	0.2	0.2	1.2	-0.4	-0.6	0.1
Taking other prescription medications	1.0	1.6	6.5	-2.5	-0.8	-1.4	-0.2	-0.3	1.0	-0.9	0.8	0.9	-1.7
Age when periods started (menarche)	0.4	1.0	5.9	-1.0	-2.4	0.0	0.2	-0.5	-1.0	-1.0	-0.7	0.4	-0.1
Bilateral oophorectomy (both ovaries removed)	2.8	3.2	5.5	-2.1	-1.6	-1.8	-1.0	2.3	2.3	-1.7	0.9	1.1	-2.3
Heel bone mineral density (BMD) T-score, automated (left)	2.5	5.6	16.9	2.6	0.9	1.1	4.1	-1.5	-0.7	-0.9	-3.1	-2.9	2.9
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.9	-0.9	-0.5	-0.3	-0.4	-0.6	-1.4	0.4	-0.1	0.0	-0.0
Qualifications: CSEs or equivalent	1.2	1.6	4.3	-0.9	0.9	-0.3	-1.0	1.9	0.0	0.6	1.8	2.1	-1.1
Serious illness, injury or assault to yourself	0.9	1.1	2.5	-1.1	-1.6	-0.8	-0.6	0.7	0.6	-1.5	0.4	1.1	-1.4
High blood pressure	0.7	2.0	6.0	-2.4	1.6	-0.2	-1.3	0.4	0.5	2.4	1.3	1.3	-0.1
Hayfever, allergic rhinitis or eczema	0.8	1.8	3.5	0.6	-1.8	-1.8	1.2	-0.2	-1.0	-1.9	-1.3	-1.6	-0.7
Multivitamins +/- minerals	0.6	0.7	2.5	1.3	-0.3	0.3	1.6	0.5	0.1	-0.4	-1.3	-0.7	0.4
Stomach or abdominal pain in last month	0.7	0.8	2.5	-1.1	0.9	0.9	-1.0	-0.9	0.5	0.3	1.6	0.4	-1.0
Supplements: Glucosamine	0.7	0.9	1.7	0.9	-0.1	-0.4	0.6	-1.1	-1.2	0.5	-1.3	-1.3	1.0
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.5	0.0	1.2	0.1	-0.8	-0.1	-1.2	0.8	0.8	0.5	-0.7
Medication: Atenolol	1.3	1.6	5.0	-1.9	-0.6	0.3	-0.7	1.4	2.2	0.4	1.0	1.7	-0.5
Medication: Levothyroxine sodium	0.5	0.9	2.5	-0.8	0.5	0.3	-0.9	-1.4	0.0	1.6	0.9	1.3	0.1
Sitting height	0.5	3.7	11.4	2.2	-0.5	0.0	3.4	-1.0	-2.3	-0.7	-1.8	-2.3	2.2
Chronic bronchitis/emphysema (father)	0.6	0.7	3.0	-0.3	0.7	1.7	0.2	-0.8	0.3	0.6	-0.7	-0.1	1.3
High blood pressure (mother)	0.3	0.4	1.5	0.3	-0.8	1.2	-0.5	-0.4	0.8	-0.1	0.7	0.1	-0.3
Body mass index (BMI)	0.5	2.0	7.4	2.2	1.6	-0.2	1.4	-0.1	-2.7	0.7	-0.7	-1.4	0.8
Impedance of leg (left)	1.9	9.3	35.7	-3.8	-0.5	1.2	-2.7	3.1	6.0	-0.1	2.5	3.3	-2.7
Leg predicted mass (left)	0.9	4.9	19.3	2.5	0.1	-1.0	2.8	-2.1	-4.4	0.4	-1.6	-1.6	2.4
Trunk fat mass	0.3	1.2	3.6	1.6	0.5	0.0	1.9	-0.1	-1.8	-0.1	-0.6	-0.7	1.1
Waist circumference	0.2	0.6	3.1	0.5	-0.2	-1.2	0.6	0.2	-1.8	-0.1	0.1	-0.8	-0.4
Number of incorrect matches in round	0.7	1.1	2.3	-0.2	-0.8	1.5	-1.3	0.6	1.1	-0.9	1.2	1.3	-1.1
Past tobacco smoking	0.3	0.5	1.4	-0.4	-1.2	-0.7	-0.2	-0.3	-0.2	-1.0	-1.0	-0.5	0.3
Alcohol usually taken with meals	0.3	0.5	2.2	-0.0	-1.5	0.6	-0.6	-1.1	-0.4	0.2	0.3	-0.4	0.3
Nervous feelings	0.7	1.4	4.3	-0.8	-2.1	-1.7	-0.3	-1.7	-0.6	-0.2	-1.0	-1.2	0.3
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.8	7.5	1.3	-0.0	-2.0	2.7	-0.8	-2.1	-0.1	-2.1	-2.1	0.9
Hearing difficulty/problems with background noise	0.9	1.4	4.7	0.5	0.7	-1.6	0.6	-1.0	-2.2	-0.9	-1.2	-1.4	0.6
Hair/balding pattern: Pattern 2	0.9	1.1	3.1	-1.4	0.5	1.1	-1.1	0.2	0.9	0.5	1.2	1.8	-0.9
Had menopause	0.3	0.3	2.0	0.7	-0.3	0.1	-0.1	-1.4	0.7	0.1	0.4	-0.4	0.3
Had other major operations	1.4	1.7	4.3	-0.7	-1.3	-0.7	-1.6	0.5	0.5	-0.9	1.9	1.5	-2.1
Forced vital capacity (FVC)	0.3	1.2	6.0	0.7	-0.8	-0.4	2.4	-0.2	-0.6	-0.2	-1.2	-0.1	1.6
Heel bone mineral density (BMD) T-score, automated (right)	1.8	4.1	11.1	2.6	1.1	1.5	3.3	-0.9	-0.5	-0.1	-2.5	-2.1	2.8
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	2.4	1.5	1.6	0.4	0.7	0.3	0.0	1.4	0.1	0.0	-0.0
Qualifications: None of the above	0.1	0.3	1.1	-0.3	1.1	0.2	0.2	-0.0	0.1	0.4	0.9	0.5	-0.1
Financial difficulties in last 2 years	0.9	1.3	4.5	-0.4	-1.2	-1.8	0.6	-0.3	-0.4	-2.1	-0.1	-0.6	-1.6
Mouth/teeth dental problems	2.4	3.7	15.1	-1.6	-0.1	0.3	-0.3	3.9	3.5	-1.0	0.4	1.5	-2.0
Heart attack	0.6	0.8	2.5	-1.1	-0.6	0.1	-1.6	-0.5	-0.3	0.7	1.4	1.1	-0.5
Allergy	0.8	1.9	4.5	0.9	2.1	1.9	-0.7	1.1	1.0	1.8	0.8	1.6	1.0
Pain all over the body in last month	1.1	1.1	3.4	-1.8	-1.4	0.9	-0.5	1.3	0.7	-1.3	-0.4	0.1	-0.8
Diabetes (self-reported)	1.0	1.6	9.7	-1.6	-3.1	-1.1	0.6	0.2	0.2	-0.9	0.3	0.7	-0.7
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	3.0	-0.8	-1.7	-0.0	0.1	0.3	0.0	-0.1	0.5	0.8	-0.1
Medication: Ramipril	1.0	1.3	4.2	-1.2	-0.8	-0.7	-1.5	0.8	0.8	0.2	1.5	0.9	-2.0
Medication: Simvastatin	2.1	3.1	6.5	-2.6	-1.8	-2.2	-2.3	0.2	0.2	-0.3	1.9	1.9	-2.0
Fluid intelligence score	0.7	1.4	4.7	-1.2	2.2	0.3	-1.3	0.0	1.4	1.1	1.2	0.9	-0.3
Illnesses of siblings	0.2	0.3	0.9	0.2	-0.8	0.1	-0.7	-0.2	0.8	0.1	-1.0	0.4	-0.1
Neuroticism score	0.9	1.9	4.3	0.1	-1.5	-1.7	1.7	-1.4	-2.1	-0.3	-1.6	-1.1	0.5
Weight	0.5	2.6	9.5	2.1	0.6	-0.6	2.3	-0.9	-3.1	0.2	-1.0	-1.3	1.4
Impedance of arm (right)	1.2	5.5	20.8	-2.2	-2.4	0.8	-1.4	1.6	4.6	-2.2	1.7	2.4	-2.3
Arm fat percentage (right)	0.2	0.6	2.5	1.6	0.8	0.4	1.2	0.6	-0.8	0.1	-0.2	-0.6	0.1
Trunk fat-free mass	1.1	6.1	17.1	2.9	0.5	-0.7	3.2	-2.1	-4.1	0.8	-2.2	-2.4	3.0
Hip circumference	0.4	1.6	7.5	1.5	0.6	-1.0	1.6	-0.1	-2.7	0.3	-0.9	-1.1	0.7
Time employed in main current job	0.8	0.9	2.6	-0.4	1.3	-0.8	-0.7	0.7	-1.4	1.6	0.6	0.8	0.6
Alcohol intake versus 10 years previously	0.3	0.4	1.3	0.3	-0.0	-1.1	0.1	0.1	-0.3	-1.1	-0.5	-1.0	-0.4
Father’s age at death	1.2	1.6	4.5	2.1	0.1	1.1	0.4	-1.8	-1.3	-0.5	-1.0	-2.0	0.3
Worrier / anxious feelings	0.8	1.4	4.6	-0.3	-1.3	-1.4	0.8	-1.5	-2.1	-0.6	-1.0	-1.3	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	7.1	-1.3	-2.7	-1.2	0.4	0.2	-1.8	-0.6	0.1	0.3	-1.0
Falls in the last year	0.4	0.6	2.3	-0.2	0.7	0.5	-0.2	-0.8	-1.5	0.5	-0.5	-0.4	1.3
Hair/balding pattern: Pattern 3	1.7	2.5	5.9	2.4	0.5	-0.8	2.4	0.2	-1.5	-0.3	-2.1	-1.8	1.6
Number of live births	0.6	0.8	3.2	0.3	-0.7	-0.1	-0.6	-0.0	0.3	-1.6	1.0	-0.6	-1.8
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.3	0.5	-1.0	-1.0	1.1	-0.0	-0.6	-0.3	-0.5	0.4	0.5
Pulse rate	0.9	1.6	4.9	1.1	0.7	-2.2	1.8	1.2	-0.9	-1.1	-0.8	-1.3	-0.3
Happiness	0.5	0.6	2.0	1.4	0.3	1.2	0.3	-1.2	-0.3	0.4	0.8	-0.5	0.4
Noisy workplace	0.2	0.2	1.0	1.0	0.3	-0.2	0.6	0.5	-0.3	0.2	-0.6	-0.1	-0.2
Qualifications: A levels/AS levels or equivalent	0.4	0.9	4.7	-0.3	-2.2	-0.2	-1.1	-0.6	0.8	0.6	0.9	1.0	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.0	-0.4	-1.4	-1.2	-0.1	-0.7	-0.9	0.7	-0.4	-0.2	0.7
Mouth/teeth dental problems: Dentures	0.9	1.5	6.3	0.7	0.7	0.2	-0.9	-2.5	-1.7	1.3	1.0	-1.0	0.8
Asthma	0.6	1.3	3.0	-1.7	-1.7	-0.8	-1.0	-1.5	-1.1	-0.0	0.7	-0.3	-1.0
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.2	4.8	1.9	-2.2	-1.4	2.1	1.0	0.1	-1.2	-1.8	-1.4	-0.2
Medication: Cholesterol lowering	2.1	3.3	15.5	-3.9	-1.3	-1.2	-2.1	-0.3	0.8	1.1	1.4	2.3	-0.4
Depression (self-reported)	0.4	0.5	1.7	-0.4	0.3	0.3	1.0	-0.7	-1.3	0.7	-0.0	-0.5	0.6
Medication: Lansoprazole	0.5	0.5	1.7	-1.0	-0.4	-0.0	-0.4	0.3	1.3	-0.0	0.1	1.1	-1.0
Prospective memory result	0.4	0.5	3.2	0.7	-1.8	-0.4	0.2	-0.4	0.0	0.5	-0.4	0.1	-0.4
Lung cancer (father)	0.2	0.2	0.7	-0.7	-0.0	0.7	-0.1	-0.3	0.2	0.8	0.1	0.5	0.5
Illnesses of mother	2.4	3.0	7.2	1.5	0.5	-0.1	2.1	-0.4	-2.3	0.6	-2.4	-1.8	2.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	2.1	0.2	-1.4	-0.4	1.2	0.1	-0.3	-0.9	-0.6	0.8	0.3
Pulse wave Arterial Stiffness index	0.5	0.6	1.8	-0.4	1.3	0.1	-0.1	-1.0	0.1	1.1	0.0	-0.3	1.3
Impedance of arm (left)	1.4	6.6	22.9	-2.8	-2.2	0.9	-1.9	1.5	4.8	-2.1	2.2	3.0	-2.3
Arm fat mass (right)	0.4	1.5	4.4	2.1	0.7	0.0	1.9	-0.3	-2.0	0.2	-0.7	-1.1	0.8
Trunk predicted mass	1.1	6.1	17.2	2.9	0.5	-0.8	3.2	-2.1	-4.2	0.7	-2.2	-2.4	2.9
Standing height	0.2	2.3	6.7	0.2	-1.7	-1.1	2.6	-1.9	-1.3	-1.1	-1.2	-0.4	2.0
Length of working week for main job	1.1	1.2	2.7	1.1	1.1	0.7	1.0	-0.3	-0.8	1.5	-1.4	0.2	1.6
Exposure to tobacco smoke at home	1.3	1.5	5.3	1.0	-0.3	-2.3	1.3	0.1	-1.0	-1.1	-1.0	-1.8	-0.2
Breastfed as a baby	1.6	2.0	6.6	0.3	0.5	1.0	0.8	-1.8	-1.7	2.0	-1.0	-0.6	2.6
Tense / ‘highly strung’	0.5	0.8	2.3	-1.3	0.9	-0.1	0.4	-0.6	-0.4	1.4	-0.6	0.8	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	1.8	0.3	-1.0	-0.7	-0.3	-1.1	-1.1	-0.7	1.0	-1.3	-1.3
Hair/balding pattern: Pattern 4	0.3	0.7	1.4	1.1	0.1	0.1	0.7	-0.9	-1.1	0.2	-0.6	-1.2	1.1
Birth weight of first child	0.3	0.6	2.7	-0.8	-0.8	-1.6	0.8	-0.5	0.6	-0.2	-0.3	0.3	-0.4
Peak expiratory flow (PEF)	0.3	0.7	1.5	-0.2	-1.1	-0.8	-0.9	-0.6	-0.7	-1.2	0.8	0.7	-1.0
Pulse wave reflection index	0.4	0.6	2.0	0.4	1.4	0.2	0.3	-0.4	0.8	1.2	-0.7	-0.3	0.8
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.1	1.0	0.5	-0.8	1.2	1.4	-0.1	-0.7	-0.5	0.3	-0.7
Loud music exposure frequency	0.3	0.3	0.9	0.1	0.6	-0.5	-0.2	-0.9	-0.8	0.3	-0.6	0.5	0.0
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	9.5	-1.6	-3.1	-0.6	-1.4	-1.6	0.8	-0.1	1.1	1.6	-0.9
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	8.7	0.7	-0.4	-1.3	0.1	-1.0	-2.9	-0.1	-0.3	-1.0	0.6
Blood clot in the leg (DVT)	0.6	0.8	2.5	0.7	1.1	0.2	0.9	-1.0	-0.1	-0.4	-0.7	-1.6	1.1
Medication: Paracetamol	0.5	0.8	2.8	-0.3	-1.7	-0.9	1.1	-0.5	-1.1	-1.0	-0.7	-0.7	-0.4
Headache pain in last month	0.2	0.3	1.2	0.3	0.8	0.0	1.1	0.6	-0.1	0.4	0.3	-0.0	0.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	7.6	2.8	0.7	0.8	0.9	0.6	-0.2	-1.3	-1.0	-1.0	-0.1
Glaucoma (self-reported)	2.5	2.9	11.8	1.6	-1.7	-1.0	1.8	0.3	1.1	-3.4	-2.0	-1.1	-1.0
Gout (self-reported)	0.8	1.1	2.6	-0.6	1.6	1.4	-0.2	0.4	1.2	1.3	0.7	1.1	0.8
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	5.9	-1.2	1.5	0.4	-1.8	-0.4	0.8	2.0	1.9	2.4	-0.7
Medication: Amlodipine	0.5	0.7	2.0	-1.4	0.2	-0.2	-1.2	-0.5	0.8	0.2	1.2	0.9	-0.6
Medication: Ventolin 100micrograms inhaler	2.2	2.8	5.7	1.8	0.0	-0.2	1.4	-1.9	-2.4	1.3	-2.1	-2.0	2.0
Birth weight	0.3	0.7	2.0	0.7	-0.3	-0.8	0.9	-0.6	-0.5	-0.7	-1.4	-1.0	0.8
Chronic bronchitis/emphysema (mother)	0.4	0.4	2.4	-1.6	0.2	-0.2	0.2	-0.1	0.3	-0.7	0.8	0.4	-0.4
High blood pressure (siblings)	0.4	0.6	2.5	-0.1	-0.2	-0.5	1.1	-0.3	-1.3	-1.6	-0.3	-0.5	0.1
Forced vital capacity (FVC), Best measure	0.2	0.7	3.3	0.1	-0.9	0.4	1.8	0.0	-0.5	-0.4	-0.7	0.5	1.2
Body fat percentage	0.1	0.4	1.3	0.7	1.0	0.4	0.8	1.1	-0.3	0.1	0.3	0.2	-0.1
Leg fat percentage (right)	0.3	1.0	3.5	0.4	1.9	0.6	-0.1	1.7	0.2	0.8	1.0	0.6	-0.8
Arm fat-free mass (right)	1.0	5.3	17.3	2.5	0.7	-0.7	3.0	-1.9	-4.2	1.0	-1.8	-1.9	2.8
Exposure to tobacco smoke outside home	3.8	5.1	11.2	1.9	0.8	-2.3	3.1	-0.2	-2.9	-1.2	-3.4	-2.8	1.7
Comparative body size at age 10	0.3	0.8	3.6	-1.0	-1.2	-1.2	-0.4	0.5	-1.9	-0.1	-0.1	0.6	-0.4
Number of full brothers	0.9	1.1	2.8	-1.6	-0.4	0.3	-0.9	0.0	0.6	0.7	1.7	1.3	-1.3
Worry too long after embarrassment	0.5	0.9	3.2	-1.1	-1.8	-1.1	0.5	-1.4	-0.6	-0.7	0.4	-0.0	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.7	0.5	-0.2	0.6	1.4	-1.1	-0.5	0.3	-0.7	-1.6	1.1
Wheeze or whistling in the chest in last year	0.3	0.5	1.7	-0.8	-0.1	-0.5	0.3	-0.5	-1.3	0.0	-0.0	-1.1	-0.7
Number of children fathered	0.7	0.8	2.8	-0.7	1.7	-0.0	0.7	1.7	0.4	0.5	0.5	0.9	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	4.5	-2.1	0.2	-0.1	-0.6	0.7	0.3	0.1	0.6	0.9	-0.3
Age at first live birth	0.8	1.5	3.8	0.7	0.0	-1.3	1.9	0.8	-1.1	0.1	-1.9	-1.3	1.3
Pulse wave peak to peak time	0.5	0.6	1.8	0.7	-1.4	0.1	0.3	1.0	-0.0	-1.0	-0.0	0.4	-1.1
Health satisfaction	0.6	0.8	3.5	-0.2	-0.4	-1.9	-0.9	-0.4	-0.6	-0.1	0.8	0.0	-1.4
Shortness of breath walking on level ground	0.8	0.9	2.8	-1.7	0.9	0.2	-0.9	0.4	-0.9	0.8	1.2	1.2	-0.5
Qualifications: College or University degree	0.3	0.9	3.3	1.5	-1.8	0.1	0.1	-0.5	0.7	-1.1	-0.6	-0.9	-0.2
Eye problems/disorders: None of the above	1.0	1.1	3.2	-1.8	-0.8	0.7	-0.9	-1.3	-0.6	1.4	0.5	0.2	1.3
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.9	-0.8	-0.4	-1.6	-0.2	-0.4	-1.7	-0.6	-0.3	0.2	0.5
Emphysema/chronic bronchitis	1.0	1.1	3.6	-0.8	1.9	1.0	0.3	1.4	-0.1	1.8	-0.0	0.2	0.9
Medication for pain relief, constipation, heartburn	1.2	2.1	7.5	1.9	2.7	1.7	0.5	-0.2	0.3	0.9	-1.1	-0.3	2.2
Neck or shoulder pain in last month	0.5	0.6	2.0	-1.3	0.1	-0.2	-0.9	0.9	0.2	-0.4	1.4	0.1	-0.9
Medication: Blood pressure	0.3	0.5	1.9	-1.4	-0.2	-0.2	-0.8	-0.8	-0.3	0.9	0.5	0.2	0.1
Angina (self-reported)	3.6	4.8	13.4	-3.7	0.9	0.3	-2.4	0.7	1.0	2.1	3.3	2.9	-1.6
Migraine (self-reported)	1.0	1.2	3.0	-0.0	-1.7	-1.6	1.1	-1.0	-0.7	0.7	-1.0	-1.4	0.3
Medication: Ibuprofen	1.3	1.5	6.3	0.7	-2.5	-1.7	1.1	0.4	0.1	-1.3	-0.9	-0.8	-0.9
Medication: Allopurinol	0.3	0.4	0.7	0.2	0.9	0.4	0.6	0.5	0.7	0.7	-0.4	0.7	0.7
Medication: Omeprazole	0.6	0.7	2.6	-1.0	-0.3	0.3	-0.7	-0.6	-0.2	-1.3	1.0	-0.2	-1.6
Medication: Seretide 50 evohaler	0.4	0.4	2.4	0.7	-0.0	-0.2	0.3	0.0	-1.6	0.7	-0.2	-0.8	0.4
Mean time to correctly identify matches	1.3	2.6	7.1	1.2	0.3	-0.4	1.4	-1.9	-2.7	1.3	-1.5	-1.7	2.1
Heart disease (mother)	0.4	0.5	2.9	0.2	0.2	0.7	0.7	0.3	1.7	-0.8	0.1	0.4	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	4.6	-0.9	-2.1	-1.4	-0.5	-0.9	-0.1	0.2	0.3	0.3	-0.7
Whole body fat mass	0.2	0.9	3.3	1.3	0.8	-0.3	1.5	-0.0	-1.8	0.4	-0.3	-0.6	0.7
Leg fat mass (right)	0.3	1.0	2.6	1.5	1.4	-0.2	1.4	0.1	-1.6	0.7	-0.2	-0.5	0.4
Arm predicted mass (right)	1.1	5.6	17.6	2.5	0.9	-0.8	3.1	-1.9	-4.2	1.0	-2.0	-2.1	3.0
Pulse rate, automated reading	0.2	0.7	2.2	0.5	0.7	-0.5	1.5	0.8	-0.8	-1.0	-0.5	-1.2	0.5
Alcohol intake frequency.	0.3	0.7	2.3	1.2	-0.3	-0.4	0.2	-0.1	-1.5	-1.4	-0.5	-0.8	-0.6
Comparative height size at age 10	0.3	1.4	6.2	1.1	1.2	0.1	2.5	-0.7	-0.4	-1.0	-0.7	-0.0	1.8
Number of full sisters	0.9	1.1	2.8	-1.7	-0.8	-0.8	-1.4	-0.3	0.1	0.2	1.4	1.3	-1.2
Suffer from ‘nerves’	0.2	0.3	0.9	0.1	-0.0	-0.9	0.9	0.3	-0.3	-0.1	-1.0	-0.8	0.4
Overall health rating	0.2	0.4	1.5	-0.3	-0.4	-0.6	0.1	-1.2	-1.0	-0.2	-0.6	-0.9	0.2
Chest pain or discomfort	0.6	0.8	3.4	-0.1	-1.1	0.0	0.3	-1.9	-1.5	-1.0	0.2	-0.4	0.1
Had major operations	0.6	0.7	2.4	-1.0	-0.1	1.0	-0.8	-0.5	-0.0	0.8	1.2	1.5	0.4
Age at last live birth	0.4	0.6	2.5	-0.5	-0.5	-1.6	0.7	0.5	-0.9	0.0	-0.6	-0.9	0.5
Family relationship satisfaction	0.7	0.8	3.1	1.8	1.3	1.2	1.1	-0.6	0.4	-0.4	-0.3	-0.5	0.3
Leg pain on walking	0.9	1.1	5.2	-0.3	-0.4	-1.6	-1.1	0.1	-2.3	0.2	-0.0	-0.1	-1.2
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	6.7	-1.8	-0.8	0.2	-2.1	1.4	-0.3	0.3	1.6	2.6	-1.8
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.5	-0.4	-0.6	-0.1	-0.3	1.6	-0.0	-0.4	1.0	0.9	-0.7
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.9	-0.1	1.4	-0.0	-0.7	-0.6	-0.2	1.1	0.3	-0.3	0.7
Medication: Aspirin	3.9	5.2	13.4	-3.7	-2.1	-1.2	-2.9	0.4	0.6	0.5	3.3	2.6	-2.5
Supplements: Vitamin C	0.5	0.6	1.5	-1.0	0.3	0.9	-0.7	0.1	0.1	1.2	0.9	0.6	0.5
Knee pain experienced in last month	1.1	1.7	8.0	0.0	-0.4	-1.6	-0.8	-2.2	-2.8	-0.0	-0.2	-0.8	-0.0
Hypertension (Self-reported)	1.0	2.7	7.6	-2.8	1.8	-0.4	-1.6	0.7	0.4	2.6	1.6	1.6	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	3.0	1.4	1.1	1.4	0.1	-0.4	0.7	1.7	0.2	-0.6	0.2
Illnesses of father: Heart disease	0.5	0.7	3.1	-1.8	-1.3	-0.7	-0.7	-0.2	0.1	0.1	0.6	0.6	-0.5
Illnesses of siblings: Diabetes	1.8	2.3	5.1	-1.7	-0.9	-1.1	-1.1	2.3	1.8	-1.1	1.1	1.1	-2.2
Smoking status: Previous	0.1	0.1	0.9	0.9	0.2	0.3	0.4	-0.1	-0.0	-0.2	0.3	-0.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	5.7	-2.1	-2.4	-1.1	0.2	-0.8	-0.8	-0.8	-0.4	0.8	-0.3
Whole body fat-free mass	1.1	6.2	20.4	2.8	0.5	-0.8	3.2	-2.2	-4.5	0.8	-2.0	-2.1	2.9
Leg fat-free mass (right)	1.2	6.2	22.3	2.6	-0.1	-1.2	3.2	-2.5	-4.7	0.2	-2.0	-1.9	2.8
Arm fat percentage (left)	0.1	0.5	2.1	1.4	0.7	0.3	1.2	0.4	-0.9	0.1	-0.0	-0.5	0.2
Average weekly red wine intake	0.5	0.8	1.9	1.2	0.4	0.2	0.4	-0.5	-0.4	1.1	-1.1	-1.1	1.4
Handedness (chirality/laterality): Left-handed	0.3	0.4	2.1	0.5	-0.2	-0.6	1.4	0.7	0.2	0.2	-0.0	0.7	0.3
Mood swings	0.9	1.6	7.2	0.3	-0.5	-0.6	1.2	-1.6	-2.7	0.3	-1.1	-0.8	1.3
Loneliness, isolation	1.5	2.1	5.0	1.5	-0.2	-0.7	1.7	-1.6	-2.2	-0.6	-1.2	-2.2	0.8
Long-standing illness, disability or infirmity	0.8	1.2	2.9	-0.0	-1.7	-1.3	0.7	-0.6	-1.2	-1.7	-1.1	-0.6	-0.8
Ever had bowel cancer screening	0.7	0.9	3.0	-1.7	0.5	-0.5	-1.7	-0.5	-0.6	0.2	1.1	-0.2	-0.8
Diabetes diagnosed by doctor	1.2	2.0	14.2	-1.2	-3.8	-1.3	0.8	-0.2	-0.1	-1.2	-0.3	0.2	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	10.7	3.3	0.3	0.6	1.5	0.6	0.5	-0.4	-0.6	-1.5	0.1
Friendships satisfaction	0.8	1.0	2.7	1.1	1.3	1.6	0.8	-1.3	0.1	-0.9	-0.8	-0.5	0.8
Qualifications: nursing, teaching	0.5	0.8	4.9	-0.3	-0.6	0.2	-0.9	-2.2	0.6	-0.9	0.6	0.5	-0.1
Commuting to job workplace: Walk	0.5	0.6	1.7	-0.6	-1.3	0.1	-0.6	-1.3	0.5	-0.8	0.5	-0.5	-0.5
Eye problems/disorders: Cataract	0.4	0.4	1.0	0.8	-0.3	-0.9	0.1	0.6	0.4	-0.9	-0.5	-0.0	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.2	0.2	1.4	0.2	0.2	0.6	-0.2	-1.2	-0.2	0.1	0.7	-0.0	0.3
Medication for cholesterol	3.2	4.8	10.5	3.0	-1.4	-0.5	3.0	-1.7	-1.4	-1.6	-3.2	-2.5	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	4.6	-1.7	0.4	-0.1	-1.9	0.9	0.5	-1.0	1.7	2.1	-1.7
Back pain experienced in last month	0.5	0.7	3.0	0.0	-0.7	-1.7	0.1	0.4	0.1	-0.6	0.4	-0.1	-1.6
Mineral and other dietary supplements	0.1	0.1	0.7	0.1	0.1	0.0	-0.1	-0.0	-0.1	-0.9	0.1	-0.2	-0.1
Breast cancer (self-reported)	1.5	1.8	5.1	-2.3	-1.0	-1.6	-0.3	0.8	0.8	-1.8	0.3	1.3	-1.7
Asthma (self-reported)	0.6	1.3	3.7	-1.4	-1.8	-0.8	-0.6	-1.9	-1.5	-0.1	0.3	-0.6	-0.5
Osteoporosis (self-reported)	0.2	0.3	1.2	0.0	-0.7	0.3	-0.2	0.4	-0.3	-0.5	0.8	0.2	-1.1
Osteoarthritis (self-reported)	1.7	2.2	5.8	-0.9	-2.0	-2.4	-0.7	-2.1	-2.3	-0.6	-0.7	-0.6	-0.3
Medication: Aspirin	4.7	6.1	15.6	-4.0	-1.9	-0.8	-3.4	0.8	0.8	0.5	3.5	2.9	-2.8
Medication: Gliclazide	0.6	0.7	2.9	-0.9	-1.4	-0.7	0.5	0.2	-0.1	-1.7	-0.9	0.1	-0.1
Illnesses of father: None of the above (group 1)	0.8	1.0	4.8	2.2	0.9	0.0	0.9	1.1	-0.5	-0.3	-0.9	-1.2	0.3
Smoking status: Current	0.2	0.4	1.1	0.3	-0.3	0.9	1.0	-0.3	-0.5	-0.1	-0.2	-1.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	2.9	1.7	-0.5	-0.4	1.3	0.1	-0.7	-1.4	-1.3	-1.2	0.2
Whole body water mass	1.1	6.1	19.9	2.9	0.5	-0.8	3.1	-2.1	-4.5	0.9	-2.0	-2.2	2.9
Leg predicted mass (right)	1.1	6.1	22.5	2.6	-0.1	-1.2	3.1	-2.4	-4.7	0.3	-2.0	-1.9	2.7
Arm fat mass (left)	0.3	1.4	4.1	1.9	0.6	-0.2	1.8	-0.2	-2.0	0.3	-0.6	-1.0	0.9
Number of self-reported non-cancer illnesses	1.2	2.0	5.5	-2.3	-2.1	-0.5	-1.1	-1.0	0.8	0.3	1.9	1.5	-1.1
Average weekly champagne plus white wine intake	1.7	2.4	9.2	1.5	-0.9	0.9	0.4	-3.0	-2.5	1.0	-0.6	-1.2	1.2
Miserableness	0.5	0.9	3.4	1.0	-1.0	0.2	1.8	-0.7	-1.2	-0.5	-0.9	0.0	0.8
Guilty feelings	0.6	0.9	2.6	0.2	-0.4	-0.7	1.3	-1.6	-0.6	0.0	-1.6	-0.6	1.0
Wears glasses or contact lenses	1.0	1.1	4.3	2.1	-0.4	0.6	1.7	-0.5	-0.3	-1.3	-0.7	-0.8	0.5
Ever taken oral contraceptive pill	1.4	1.5	5.0	2.0	1.0	1.8	0.5	2.2	0.9	0.3	0.3	0.7	-0.1
Hearing aid user	0.9	1.1	3.0	-0.2	0.9	0.2	-1.7	0.6	0.6	1.0	1.3	1.4	-1.2
Mother’s age at death	1.2	1.5	3.7	0.6	-0.5	-0.7	1.6	-0.9	-0.6	-0.6	-1.9	-1.9	1.5
Financial situation satisfaction	0.9	1.2	2.4	-1.1	1.0	-1.0	-1.1	-1.2	-0.3	1.5	1.5	0.8	-0.6
Tinnitus: Yes, now most or all of the time	2.1	2.5	5.8	-2.0	-1.6	-2.4	-1.8	0.3	0.2	-1.6	0.9	0.2	-2.4
Commuting to job workplace: Public transport	0.6	0.7	2.0	-1.0	0.3	-1.1	-1.0	-1.4	-0.9	0.5	0.2	0.4	-0.6
Eye problems/disorders: Glaucoma	2.2	2.6	9.6	1.9	-1.3	-0.7	1.9	0.1	0.9	-3.1	-1.9	-1.5	-0.8
Medication: Blood pressure	1.0	1.8	3.2	-1.8	1.3	0.0	-1.5	1.1	1.1	1.3	1.8	1.7	-1.0
Pain type(s) experienced in last month: Hip pain	0.9	1.1	3.6	0.5	1.9	-1.0	-0.8	-0.2	-0.1	1.0	1.5	0.1	-1.6
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.7	0.2	0.5	-0.4	0.4	-0.8	-0.3	0.8	-0.2	-0.3	0.2
High cholesterol (Self-reported)	2.3	4.1	12.5	-3.5	-0.6	-0.5	-3.0	-0.1	1.6	1.9	2.6	2.2	-1.2
Medication: Bendroflumethiazide	0.4	0.6	1.6	-1.2	0.9	-0.4	-0.2	-0.5	1.3	0.4	0.5	1.2	0.1
Medication: Paracetamol	0.2	0.3	0.8	-0.5	-0.9	-0.8	0.7	-0.7	-0.3	-0.0	-0.3	-0.2	-0.5
Medication: Lisinopril	0.8	1.1	2.5	-1.6	0.9	0.4	-0.5	1.3	1.0	1.1	1.2	1.2	-0.4
Medication: Atorvastatin	1.6	2.0	5.7	-2.4	0.0	1.3	-1.0	-1.3	1.2	1.9	0.3	1.4	1.6
Illnesses of father: High blood pressure	0.9	1.1	3.1	-0.7	-0.8	-0.1	-1.2	0.2	1.4	0.1	1.7	0.6	-1.8
Alcohol drinker status: Never	1.4	1.6	7.5	1.4	0.6	-0.4	-0.0	-1.0	-2.7	-0.2	-0.9	-2.0	0.8
Ever smoked	0.4	0.8	2.8	0.6	1.7	1.0	0.1	0.7	0.1	1.2	1.1	0.1	-0.5
Basal metabolic rate	0.9	4.8	16.6	2.5	0.5	-0.8	2.9	-1.8	-4.1	0.7	-1.7	-1.8	2.5
Leg fat percentage (left)	0.1	0.5	2.3	0.4	1.5	0.3	0.2	1.2	-0.3	0.6	0.5	0.2	-0.5
Arm fat-free mass (left)	1.0	5.0	16.6	2.3	0.6	-1.0	2.9	-1.7	-4.1	0.9	-2.0	-2.1	2.5
Number of operations (self-reported)	1.8	2.7	6.2	-1.8	-2.5	-2.2	-0.9	-0.4	-0.4	-2.5	1.1	0.7	-1.8
Average weekly beer plus cider intake	0.9	1.3	3.5	-1.4	1.9	-0.0	-1.5	-0.1	0.5	1.8	0.9	1.2	-0.1
Irritability	0.3	0.5	2.1	-0.2	-0.0	-0.0	0.7	-0.7	-1.5	-0.2	-0.8	0.1	1.0
Risk taking	0.8	1.2	5.5	-0.1	-2.3	-0.9	0.9	-0.7	-1.3	-1.5	-0.7	-0.1	0.0
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.9	-0.9	0.8	-0.0	-0.2	0.4	-0.2	-0.0	0.1	0.2	-0.5
Fractured/broken bones in last 5 years	1.5	1.9	4.6	-2.0	0.2	-0.6	-2.0	0.1	1.2	0.3	2.1	1.7	-1.3
Age started oral contraceptive pill	0.5	0.6	2.7	-0.4	0.9	0.8	-0.7	0.2	1.6	-0.8	0.6	0.4	-0.3
Diastolic blood pressure, automated reading	0.9	2.9	9.1	1.0	3.0	1.5	1.8	0.8	-0.5	2.3	-0.9	-0.6	2.4
Ever depressed for a whole week	0.4	0.5	1.4	-0.4	0.4	-0.0	-0.9	-0.6	-1.0	1.2	0.6	-0.4	-0.5
Unable to work because of sickness or disability	1.2	1.5	5.0	-1.7	-2.2	-1.1	0.1	-1.6	-0.7	-1.1	-1.0	-0.8	0.6
Commuting to job workplace: Cycle	1.0	1.2	4.7	0.6	0.8	1.5	0.7	-1.0	2.2	0.0	-0.4	-0.2	1.6
Myopia	0.7	1.0	3.5	-0.4	-1.7	-0.9	-0.2	-0.8	-0.5	-1.9	-1.1	-0.1	-0.2
Vascular/heart problems diagnosed by doctor	0.8	2.1	6.4	2.2	-1.6	-0.0	1.5	-0.2	-0.5	-2.5	-1.7	-1.3	0.1
Cholesterol lowering medication	3.2	4.8	10.8	-3.0	-0.4	-0.1	-3.2	1.1	1.4	0.7	3.3	2.8	-2.4
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.5	-0.6	0.1	0.7	-0.4	-0.4	-0.1	-1.6	0.7	-0.7	-1.3
Pain experienced in last month	0.8	1.3	3.3	1.8	1.3	1.0	1.1	-0.3	0.4	0.8	-1.3	-0.3	1.7
Supplements: Calcium	1.4	1.6	7.4	-2.7	-0.7	-1.1	-1.7	0.9	0.3	-0.4	0.6	1.1	-1.1
Basal cell carcinoma (self-reported)	0.8	1.0	5.8	-0.1	-1.1	-0.1	-0.3	-0.8	-0.1	-2.4	0.8	-0.5	-1.1
Heart attack/myocardial infarction (self-reported)	0.9	1.1	3.1	-1.0	-0.7	0.5	-1.8	-0.6	0.0	0.8	1.7	1.3	-0.6
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	3.8	1.2	1.0	0.0	1.3	-1.1	-0.4	-0.6	-1.2	-2.0	1.3
Heart disease (siblings)	0.4	0.5	2.5	0.1	1.6	-0.7	0.8	-0.0	-0.7	-0.1	0.2	-0.6	0.2
Alcohol drinker status: Previous	1.0	1.2	4.0	-0.4	-1.5	1.0	-0.9	-0.0	1.1	-1.1	0.3	2.0	-0.8
Pack years of smoking	0.4	0.6	1.9	-0.2	1.4	1.0	0.1	0.5	-0.7	0.2	-0.8	-0.8	1.0
Impedance of whole body	1.8	9.0	32.6	-3.5	-1.8	0.9	-2.3	2.6	5.7	-1.4	2.5	3.5	-2.9
Leg fat mass (left)	0.2	0.9	3.4	1.2	1.1	-0.5	1.3	0.0	-1.9	0.6	-0.2	-0.6	0.4
Arm predicted mass (left)	0.8	4.3	14.1	2.3	0.5	-0.9	2.7	-1.5	-3.8	0.7	-1.8	-2.0	2.2