TWAS hub - KCNRG

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0520	0.0220	1.4e-03	0.011	0.015	0.008	0.018	0.011	6.6e-03	2.2e-03	1.7e-02	0.00082	7.0e-03
2	TCGA	Brain Lower Grade Glioma	0.0296	0.0152	9.1e-06	0.041	0.048	0.045	NA	0.043	1.8e-05	3.5e-06	7.2e-06	NA	1.1e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Commuting to job workplace: Car/motor vehicle	12.3	14.1	19.2	-3.0	-4.4
Leg fat percentage (right)	6.3	22.7	29.1	-4.0	-5.4
Diabetes (father)	5.5	6.8	12.2	-1.1	-3.5
Leg fat percentage (left)	5.1	18.3	21.8	-3.8	-4.7
Mouth/teeth dental problems: Mouth ulcers	5.0	7.9	12.5	-3.5	-1.8
Leg fat mass (right)	4.6	17.7	21.8	-3.7	-4.7
Body fat percentage	4.4	17.5	18.9	-4.0	-4.3
Commuting to job workplace: Walk	4.4	4.7	6.5	1.7	2.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.1	4.8	5.0	2.2	2.2
Lupus	3.8	5.7	7.1	-2.1	-2.7
Leg fat mass (left)	3.8	15.0	17.8	-3.5	-4.2
Number of incorrect matches in round	3.6	6.1	8.8	-1.8	-3.0
Noisy workplace	3.6	4.5	7.2	-1.3	-2.7
Whole body fat mass	3.6	15.2	16.0	-3.8	-4.0
Trunk fat percentage	3.5	13.9	13.9	-3.7	-3.7
Trunk fat mass	3.3	14.0	14.7	-3.6	-3.8
Schizophrenia vs Biploar Disorder	3.1	4.1	5.2	-1.7	-2.3
Impedance of leg (right)	2.8	13.6	21.4	-2.4	-4.6
Family relationship satisfaction	2.8	3.5	6.5	-0.6	-2.6
Body Mass Index (BMI) (2010)	2.6	3.6	3.9	-2.0	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	2.6	3.4	5.2	-1.2	-2.3
Supplements: Vitamin C	2.6	3.1	5.9	-0.5	-2.4
Comparative body size at age 10	2.5	6.8	12.2	-3.5	-1.2
Mouth/teeth dental problems	2.4	3.7	5.8	2.4	1.3
Illnesses of siblings	2.4	3.4	6.7	2.6	0.4
Number of live births	2.4	3.3	5.9	0.9	2.4
Stomach or abdominal pain in last month	2.3	2.8	4.0	-2.0	-1.3
Had other major operations	2.3	2.8	3.0	-1.7	-1.6
Father’s age at death	2.3	3.1	3.4	-1.8	-1.7
Commuting to job workplace: Public transport	2.3	2.8	4.3	1.1	2.1
Medication: Lisinopril	2.3	3.0	4.7	1.1	2.2
High blood pressure	2.2	6.1	12.2	0.1	3.5
Arm fat percentage (right)	2.2	8.5	9.8	-2.7	-3.1
Neuroticism (2016)	2.1	3.0	3.3	-1.7	-1.8
Tinnitus: Yes, but not now, but have in the past	2.1	2.3	4.6	-2.1	-0.1
Arm fat mass (left)	2.1	8.8	9.4	-2.8	-3.1
Vascular/heart problems diagnosed by doctor	2.1	5.7	11.1	-0.5	-3.3
Coronary Artery Disease (CAD)	2.0	2.4	4.4	-2.1	-0.6
Arm fat mass (right)	2.0	8.4	9.1	-2.8	-3.0
Hypertension (Self-reported)	2.0	5.7	11.3	-0.2	3.4
Arm fat percentage (left)	2.0	8.0	8.8	-2.7	-3.0
Eye problems/disorders: Cataract	2.0	2.3	3.2	-1.8	-1.2
Mother’s age at death	2.0	2.5	2.6	-1.5	-1.6
Financial difficulties in last 2 years	1.9	2.6	2.9	-1.5	-1.7
Number of full sisters	1.9	2.3	2.4	1.5	1.5
Hearing aid user	1.9	2.2	3.8	-0.8	-1.9
Fractured/broken bones in last 5 years	1.9	2.4	3.4	1.2	1.8
Respiratory disease	1.8	3.9	7.5	-0.6	-2.7
Impedance of leg (left)	1.8	8.9	12.8	-2.2	-3.6
Medication: Lansoprazole	1.8	2.0	3.3	-0.9	-1.8
Illnesses of mother	1.8	2.2	2.9	1.7	1.3
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	4.1	-2.0	-0.2
Friendships satisfaction	1.8	2.2	3.8	-0.8	-1.9
Diastolic blood pressure, automated reading	1.8	5.6	10.7	-0.6	3.3
Cardiovascular Disease	1.7	5.6	11.3	-0.0	3.4
Angina	1.7	2.2	2.7	1.6	1.3
Hair/balding pattern: Pattern 4	1.7	4.0	6.4	1.3	2.5
Medication: Paracetamol	1.7	2.8	4.5	-1.1	-2.1
Worry too long after embarrassment	1.7	2.9	4.3	1.2	2.1
Smoking status: Current	1.7	2.6	5.2	0.3	2.3
Tinnitus: Yes, now most or all of the time	1.7	2.0	2.8	1.7	1.1
Eye problems/disorders: Diabetes related eye disease	1.6	1.8	2.3	-1.1	-1.5
Current tobacco smoking	1.6	2.6	5.0	-0.3	2.2
Waist circumference	1.6	6.0	6.9	-2.3	-2.6
Average weekly red wine intake	1.6	2.4	3.2	1.8	1.3
Illnesses of father: High blood pressure	1.6	2.0	4.0	-2.0	-0.1
Alzheimer’s Disease (in father)	1.5	1.6	2.0	1.1	1.4
Supplements: Zinc	1.5	1.7	2.5	-0.9	-1.6
Medication: Co-codamol	1.5	1.7	3.1	0.6	1.7
Pack years adult smoking proportion	1.5	2.3	3.1	1.2	1.8
Had menopause	1.5	1.9	3.7	-0.0	1.9
Forced vital capacity (FVC), Best measure	1.5	5.6	7.7	-1.9	-2.8
Angina (self-reported)	1.5	2.0	2.9	1.7	1.1
Chronic bronchitis/emphysema (father)	1.4	1.6	2.2	1.0	-1.5
Weight	1.4	7.0	7.9	-2.5	-2.8
Hip circumference	1.4	6.0	6.3	-2.5	-2.4
Mouth/teeth dental problems: Bleeding gums	1.4	1.9	3.1	-0.7	-1.8
Illness, injury, bereavement, stress in last 2 years	1.4	1.7	3.3	0.2	1.8
Ever taken oral contraceptive pill	1.4	1.6	1.8	1.3	1.2
Hypothyroidism (self reported)	1.3	3.1	4.6	1.3	-2.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.0	5.4	-1.6	-2.3
Pulse wave Arterial Stiffness index	1.3	1.5	2.7	-1.7	0.6
Mouth/teeth dental problems: Loose teeth	1.3	1.5	1.8	1.4	1.1
Average weekly champagne plus white wine intake	1.3	1.8	2.6	-1.6	-1.0
Pulse wave peak to peak time	1.2	1.4	2.1	1.4	-0.8
Eye problems/disorders: None of the above	1.2	1.4	1.8	1.0	1.3
Guilty feelings	1.2	1.8	3.6	1.9	0.2
Primary Biliary Cirrhosis	1.1	1.6	3.3	-0.1	-1.8
Allergy or Eczema	1.1	2.8	4.2	-1.2	-2.1
Lung FVC	1.1	5.6	6.1	-2.5	-2.2
Age when periods started (menarche)	1.1	2.7	3.6	1.3	1.9
Body mass index (BMI)	1.1	4.8	4.9	-2.1	-2.2
Hearing difficulty/problems with background noise	1.1	1.8	1.8	-1.3	1.4
Fluid intelligence score	1.1	2.4	4.6	-2.2	-0.3
Lung cancer (father)	1.1	1.3	2.5	-1.6	0.0
Number of children fathered	1.1	1.2	2.5	-1.6	-0.1
Worry (Nagel 2018)	1.0	2.2	3.8	0.8	1.9
Ever had hysterectomy (womb removed)	1.0	1.1	1.4	0.9	1.2
Taking other prescription medications	1.0	1.6	2.5	-0.9	-1.6
Ulcerative Colitis	0.9	1.4	2.3	0.7	-1.5
Exposure to tobacco smoke at home	0.9	1.1	1.3	-1.1	-0.9
Medication: Allopurinol	0.9	1.2	2.0	-1.4	-0.6
Alcohol intake frequency.	0.9	2.1	2.9	1.7	1.1
Medication: Aspirin	0.9	1.2	1.7	0.8	1.3
Ever had bowel cancer screening	0.9	1.1	1.5	-0.8	-1.2
Breast cancer (self-reported)	0.9	1.1	1.8	-1.3	-0.7
Osteoporosis (self-reported)	0.9	1.1	2.2	-1.5	-0.1
Wears glasses or contact lenses	0.9	1.1	2.0	1.4	-0.3
Eye problems/disorders: Glaucoma	0.9	1.0	1.4	-0.8	-1.2
Medication: Blood pressure	0.9	1.6	3.3	0.1	1.8
Alcohol drinker status: Never	0.9	1.0	2.0	-0.1	1.4
Ulcerative Colitis (UC)	0.8	1.6	2.9	0.5	-1.7
Fasting Glucose	0.8	0.9	1.7	0.3	1.3
BMI	0.8	4.5	4.7	-2.2	-2.1
Average weekly spirits intake	0.8	1.0	1.3	-1.2	0.7
Frequency of depressed mood in last 2 weeks	0.8	1.1	1.2	-1.0	-1.1
Medication: Levothyroxine sodium	0.8	1.3	2.2	0.6	-1.5
Forced vital capacity (FVC)	0.8	3.0	4.1	-1.4	-2.0
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	2.0	0.2	1.4
Hair/balding pattern: Pattern 3	0.8	1.3	1.6	1.2	-1.0
Pulse rate	0.8	1.3	2.6	-1.6	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	1.1	1.1	-0.8
Depression (self-reported)	0.8	0.9	1.6	1.3	-0.4
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	2.5	0.8	-1.6
Chronic bronchitis/emphysema (mother)	0.8	0.9	1.6	1.3	0.4
Leg pain on walking	0.8	1.0	1.5	-1.2	-0.7
Osteoarthritis (self-reported)	0.8	1.0	1.2	-1.1	-0.9
High cholesterol (Self-reported)	0.8	1.4	2.6	0.3	1.6
Alzheimer’s Disease (in mother)	0.7	0.8	1.1	-1.1	-0.6
Reaction Time	0.7	1.3	2.6	-0.0	-1.6
Ever used hormone-replacement therapy (HRT)	0.7	0.8	1.0	1.0	0.8
Medication: Metformin	0.7	1.0	1.7	-1.3	-0.6
Allergy	0.7	1.5	2.8	0.5	1.7
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	1.9	0.2	-1.4
Worrier / anxious feelings	0.7	1.4	1.8	1.0	1.3
Mouth/teeth dental problems: Dentures	0.7	1.1	2.2	-1.5	-0.2
Birth weight	0.7	1.5	3.0	0.2	1.7
Number of full brothers	0.7	0.8	1.6	-0.3	1.3
Had major operations	0.7	0.8	1.2	1.1	0.7
Medication: Gliclazide	0.7	0.8	0.8	0.9	0.9
Illnesses of father: None of the above (group 1)	0.7	0.9	1.3	0.8	1.1
Arm fat-free mass (left)	0.7	3.4	3.6	-1.8	-1.9
Pain experienced in last month	0.7	1.2	1.6	-0.9	1.3
Deep venous thrombosis (DVT) (self-reported)	0.7	0.8	1.6	-0.3	-1.3
Rheumatoid Arthritis	0.6	0.8	1.1	1.1	0.7
Schizophrenia (2014)	0.6	1.4	2.2	-0.8	-1.5
Blood Eosinophil Count	0.6	4.7	5.6	-2.4	-1.9
Heel T-Score	0.6	5.1	5.9	2.4	2.1
Systolic Blood Pressure	0.6	2.8	5.6	-0.2	2.4
Lung FEV1/FVC ratio	0.6	3.2	5.8	0.8	2.4
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	1.0	0.7	-1.0
Systolic blood pressure, automated reading	0.6	1.8	3.1	-0.7	1.8
Serious illness, injury or assault to yourself	0.6	0.8	1.5	-0.2	-1.2
Time employed in main current job	0.6	0.7	1.0	-1.0	-0.6
Asthma	0.6	1.2	2.4	-0.3	-1.6
Peak expiratory flow (PEF)	0.6	1.4	2.5	1.6	0.5
Pulse wave reflection index	0.6	0.8	1.6	-0.1	1.3
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.3	1.1	0.4
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	1.6	-0.5	1.2
High blood pressure (siblings)	0.6	0.9	1.6	-1.2	0.5
Medication: Blood pressure	0.6	1.0	2.0	-0.1	1.4
Mean time to correctly identify matches	0.6	1.1	2.1	-0.0	-1.5
Illnesses of siblings: Diabetes	0.6	0.7	1.2	-1.1	-0.6
Smoking status: Previous	0.6	0.9	0.9	-0.9	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	2.5	1.6	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	0.9	0.6	1.0
Miserableness	0.6	1.0	1.9	1.4	0.1
Average weekly beer plus cider intake	0.6	0.9	1.0	0.9	1.0
Ever depressed for a whole week	0.6	0.8	0.8	0.8	0.9
Commuting to job workplace: Cycle	0.6	0.7	1.4	0.0	1.2
Heart disease (siblings)	0.6	0.7	1.3	-1.1	-0.3
Arm predicted mass (left)	0.6	2.9	3.0	-1.7	-1.7
Depression (Nagel 2018)	0.5	0.8	0.9	-1.0	-0.7
Breast Cancer	0.5	1.3	2.4	0.4	1.6
Blood Platelet Count	0.5	5.7	10.9	-0.7	-3.3
Smoking Status	0.5	1.2	2.3	-0.3	1.5
Multivitamins +/- minerals	0.5	0.6	1.2	1.1	0.2
Qualifications: None of the above	0.5	1.1	2.0	1.4	-0.4
Medication: Simvastatin	0.5	0.7	1.4	-0.0	1.2
Neuroticism score	0.5	1.1	1.7	0.8	1.3
Falls in the last year	0.5	0.6	1.2	0.0	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.1	-1.0	-0.3
Length of working week for main job	0.5	0.6	0.8	0.9	0.5
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	1.6	0.4	-1.3
Glaucoma (self-reported)	0.5	0.6	1.3	-0.0	-1.1
Medication: Amlodipine	0.5	0.7	1.4	-1.2	-0.2
Wheeze or whistling in the chest in last year	0.5	0.8	1.6	1.2	0.4
Heart disease (mother)	0.5	0.6	0.7	0.9	0.7
Suffer from ‘nerves’	0.5	0.8	1.2	0.6	1.1
Illnesses of father: Heart disease	0.5	0.7	1.4	-1.2	-0.2
Asthma (self-reported)	0.5	1.1	2.2	-0.1	-1.5
Medication: Aspirin	0.5	0.7	1.1	0.5	1.1
Pack years of smoking	0.5	0.7	0.9	0.7	1.0
Impedance of whole body	0.5	2.6	3.7	-1.3	-1.9
Mean Putamen Volume	0.4	0.4	0.5	-0.6	0.7
Type 2 Diabetes (T2D) (2012)	0.4	0.4	0.8	0.9	0.2
Hand grip strength (left)	0.4	1.0	1.9	-0.1	1.4
Vitamin and mineral supplements	0.4	0.6	1.1	-0.3	1.0
Severe depression (siblings)	0.4	0.4	0.5	0.6	0.7
Qualifications: CSEs or equivalent	0.4	0.6	1.0	0.4	-1.0
Supplements: Glucosamine	0.4	0.5	1.1	1.0	-0.1
Medication: Atenolol	0.4	0.5	0.7	-0.5	0.8
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	2.0	-0.9	-1.4
Medication: Ventolin 100micrograms inhaler	0.4	0.6	1.0	-1.0	-0.3
Arm fat-free mass (right)	0.4	1.8	2.0	-1.3	-1.4
Medication: Ibuprofen	0.4	0.5	0.9	-0.9	-0.3
Medication: Seretide 50 evohaler	0.4	0.4	0.7	-0.5	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	0.4	-0.6	-0.6
Medication for cholesterol	0.4	0.6	1.1	-0.2	-1.1
Back pain experienced in last month	0.4	0.5	0.8	0.9	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	1.8	-0.1	-1.3
Supplements: Fish oil (including cod liver oil)	0.4	0.6	0.9	0.5	0.9
Medication: Paracetamol	0.4	0.7	1.1	-0.5	-1.1
Irritability	0.4	0.6	0.8	-0.6	-0.9
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.0	0.2	-1.0
Unable to work because of sickness or disability	0.4	0.5	1.1	0.1	-1.0
Cholesterol lowering medication	0.4	0.6	1.1	1.0	0.3
Bipolar Disorder (2018)	0.3	0.4	0.7	-0.3	0.9
Bipolar Disorder (2011)	0.3	0.3	0.4	0.6	-0.4
LDL Cholesterol	0.3	0.5	0.9	0.2	0.9
Sensitivity / hurt feelings	0.3	0.5	0.6	-0.8	0.6
Relative age of first facial hair	0.3	0.6	0.7	-0.8	-0.8
Hand grip strength (right)	0.3	0.8	1.5	0.3	1.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.4	-0.6	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	1.4	1.2	0.3
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.7	0.8	-0.2
Nervous feelings	0.3	0.6	1.2	0.0	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.4	1.2	0.3
Heart attack	0.3	0.4	0.8	0.3	-0.9
Pain all over the body in last month	0.3	0.4	0.6	-0.2	-0.8
Happiness	0.3	0.3	0.5	0.7	-0.4
Qualifications: A levels/AS levels or equivalent	0.3	0.6	0.9	-1.0	0.5
Medication: Cholesterol lowering	0.3	0.4	0.7	0.3	0.8
Prospective memory result	0.3	0.4	0.6	-0.8	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.7	-0.6	-0.8
Blood clot in the leg (DVT)	0.3	0.4	0.7	-0.2	-0.8
Shortness of breath walking on level ground	0.3	0.4	0.7	-0.2	-0.8
Medication: Omeprazole	0.3	0.3	0.6	0.2	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.7	0.0	0.9
Arm predicted mass (right)	0.3	1.7	1.8	-1.3	-1.3
Pulse rate, automated reading	0.3	1.0	1.7	-0.4	1.3
Loneliness, isolation	0.3	0.4	0.8	-0.9	0.2
Financial situation satisfaction	0.3	0.4	0.5	-0.7	-0.6
Ever smoked	0.3	0.6	0.6	-0.8	0.7
Basal metabolic rate	0.3	1.4	1.7	-1.1	-1.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.7	0.3	0.9
Supplements: Calcium	0.3	0.3	0.6	-0.8	0.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	0.7	0.4	-0.8
Alcohol drinker status: Previous	0.3	0.3	0.6	-0.8	-0.1
Alzheimer’s Disease (including proxy)	0.2	0.3	0.6	0.2	0.8
Irritable Bowel Disease (IBD)	0.2	0.5	1.0	0.2	-1.0
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.1	-1.0	0.1
Ovarian Cancer	0.2	0.3	0.5	-0.2	-0.7
Prostate Cancer	0.2	0.3	0.6	0.1	0.8
Height	0.2	3.4	3.5	-1.8	-1.9
Hearing difficulty/problems: Yes	0.2	0.2	0.4	-0.3	-0.7
Diabetes (mother)	0.2	0.3	0.5	-0.7	-0.2
Townsend deprivation index at recruitment	0.2	0.2	0.4	0.6	0.4
Average weekly fortified wine intake	0.2	0.2	0.4	-0.6	-0.1
Maternal smoking around birth	0.2	0.2	0.5	0.7	-0.1
Fed-up feelings	0.2	0.4	0.6	0.8	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.5	0.2	-0.7
Relative age voice broke	0.2	0.3	0.5	0.3	0.7
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.7	-0.4	-0.8
Sitting height	0.2	1.1	2.0	0.5	1.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.5	0.4	-0.7
Hair/balding pattern: Pattern 2	0.2	0.2	0.5	-0.2	0.7
Alcohol intake versus 10 years previously	0.2	0.3	0.5	0.5	-0.7
Tense / ‘highly strung’	0.2	0.3	0.5	-0.3	0.7
Birth weight of first child	0.2	0.5	0.8	-0.3	0.9
Exposure to tobacco smoke outside home	0.2	0.3	0.3	0.4	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.4	-0.7	-0.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.4	0.1	0.7
Mood swings	0.2	0.4	0.5	0.5	-0.7
Long-standing illness, disability or infirmity	0.2	0.3	0.5	0.3	-0.7
Mineral and other dietary supplements	0.2	0.2	0.4	-0.6	0.3
Medication: Bendroflumethiazide	0.2	0.4	0.5	-0.4	0.7
Medication: Atorvastatin	0.2	0.3	0.5	0.7	-0.1
Age started oral contraceptive pill	0.2	0.2	0.4	-0.2	0.6
Depressed Affect (Nagel 2018)	0.1	0.2	0.2	0.4	0.4
Intelligence (Savage-Jansen 2018)	0.1	0.5	0.7	-0.8	0.5
Neuroticism (Nagel 2018)	0.1	0.1	0.2	0.2	0.5
Schizophrenia (2018)	0.1	0.2	0.3	0.5	-0.4
Age at First Birth	0.1	0.1	0.2	-0.1	0.5
Crohns Disease (2012)	0.1	0.2	0.5	-0.0	-0.7
HbA1C	0.1	0.1	0.2	0.4	-0.1
HDL Cholesterol	0.1	0.2	0.4	0.6	-0.3
Triglycerides	0.1	0.2	0.3	0.3	0.6
Blood Red Count	0.1	1.4	1.6	-1.1	-1.3
Blood White Count	0.1	0.5	0.6	-0.8	0.6
Waist Hip Ratio (WHR)	0.1	0.3	0.6	0.1	-0.8
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.4	0.0	0.6
Chronotype (morning person)	0.1	0.3	0.5	0.7	0.1
Tanning	0.1	0.8	1.0	0.7	1.0
Number of treatments/medications taken	0.1	0.1	0.2	-0.2	-0.5
Medication for hormone replacement therapy	0.1	0.1	0.1	-0.4	-0.0
Past tobacco smoking	0.1	0.2	0.5	0.7	0.0
Alcohol usually taken with meals	0.1	0.2	0.2	0.4	0.4
Medication: Ramipril	0.1	0.1	0.3	-0.5	0.1
Trunk fat-free mass	0.1	0.4	0.8	-0.3	-0.9
Trunk predicted mass	0.1	0.6	1.0	-0.4	-1.0
Standing height	0.1	1.5	2.1	-0.9	-1.5
Gout (self-reported)	0.1	0.1	0.2	-0.4	0.1
Age at first live birth	0.1	0.1	0.2	0.1	0.5
Medication for pain relief, constipation, heartburn	0.1	0.2	0.5	0.7	-0.1
Neck or shoulder pain in last month	0.1	0.1	0.2	-0.4	-0.3
Overall health rating	0.1	0.2	0.3	-0.6	-0.4
Chest pain or discomfort	0.1	0.1	0.2	0.2	-0.4
Knee pain experienced in last month	0.1	0.2	0.3	0.0	-0.6
Number of self-reported non-cancer illnesses	0.1	0.2	0.3	0.4	-0.5
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.3	-0.5	-0.2
Risk taking	0.1	0.2	0.3	-0.2	0.6
Myopia	0.1	0.1	0.2	-0.4	0.4
Basal cell carcinoma (self-reported)	0.1	0.1	0.2	-0.2	-0.4
Bipolar Disorder or Schizophrenia	0.0	0.1	0.1	0.3	0.2
Crohns Disease (2017)	0.0	0.1	0.2	-0.4	0.2
Major Depression (MDD)	0.0	0.0	0.0	0.2	0.1
Neuroticism	0.0	0.1	0.2	0.3	0.4
Hair Pigment	0.0	0.6	1.1	-0.4	-1.1
Leg fat-free mass (left)	0.0	0.1	0.1	-0.3	-0.3
High blood pressure (mother)	0.0	0.0	0.0	0.0	0.1
Leg predicted mass (left)	0.0	0.1	0.1	-0.4	-0.3
Diabetes (self-reported)	0.0	0.1	0.1	0.2	0.3
Impedance of arm (right)	0.0	0.1	0.2	0.0	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.1	0.1	-0.1	-0.3
Impedance of arm (left)	0.0	0.1	0.1	0.4	-0.2
Breastfed as a baby	0.0	0.0	0.0	0.0	-0.1
Loud music exposure frequency	0.0	0.0	0.1	-0.3	-0.1
Headache pain in last month	0.0	0.1	0.1	0.2	-0.2
Health satisfaction	0.0	0.0	0.1	-0.1	-0.2
Qualifications: College or University degree	0.0	0.0	0.1	0.1	-0.3
Emphysema/chronic bronchitis	0.0	0.0	0.1	0.2	-0.1
Migraine (self-reported)	0.0	0.0	0.0	0.2	0.0
Comparative height size at age 10	0.0	0.0	0.0	0.0	-0.1
Age at last live birth	0.0	0.1	0.1	-0.3	0.0
Whole body fat-free mass	0.0	0.2	0.3	-0.4	-0.6
Leg fat-free mass (right)	0.0	0.2	0.4	0.2	0.7
Diabetes diagnosed by doctor	0.0	0.0	0.1	0.3	0.1
Qualifications: nursing, teaching	0.0	0.1	0.1	-0.3	-0.1
Whole body water mass	0.0	0.2	0.3	-0.3	-0.6
Leg predicted mass (right)	0.0	0.2	0.4	0.2	0.6
Number of operations (self-reported)	0.0	0.0	0.1	-0.0	-0.3

Hub : Genes

KCNRG

Models

Trait associations