Hub : Genes

KDM5A

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1011	0.0326	1.1e-04	0.059	NA	0.046	NA	0.048	2.2e-05	NA	1.7e-04	NA	1.2e-04
2	GTEx	Brain Nucleus accumbens basal ganglia	0.2420	0.0900	4.0e-03	0.005	NA	0.004	NA	0.009	2.3e-01	NA	2.5e-01	NA	1.8e-01
3	GTEx	Cells EBV-transformed lymphocytes	0.2530	0.1000	2.1e-03	0.155	NA	0.125	NA	0.139	9.2e-06	NA	7.0e-05	NA	2.9e-05
4	GTEx	Esophagus Muscularis	0.1020	0.0410	1.5e-03	0.055	NA	0.036	NA	0.043	3.1e-04	NA	3.0e-03	NA	1.2e-03
5	GTEx	Nerve Tibial	0.1176	0.0475	4.9e-03	0.003	NA	-0.004	NA	-0.003	1.8e-01	NA	9.6e-01	NA	7.1e-01
6	GTEx	Whole Blood	0.0690	0.0250	4.2e-04	0.077	NA	0.048	NA	0.069	1.2e-07	NA	3.0e-05	NA	6.2e-07
7	METSIM	Adipose	0.0453	0.0191	4.4e-03	-0.001	0.016	0.008	0.016	0.000	4.9e-01	1.4e-03	1.7e-02	1.7e-03	2.9e-01
8	NTR	Blood	0.0407	0.0106	5.1e-10	0.031	0.030	0.024	0.029	0.028	2.7e-10	4.4e-10	1.8e-08	9.0e-10	1.3e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.6	1.0	2.5	1.6	0.6	-0.7	1.1	-0.4	1.2	0.9	1.0
Bipolar Disorder or Schizophrenia	0.7	1.6	2.8	1.6	0.9	-1.1	1.4	1.1	1.7	1.1	1.1
Depressed Affect (Nagel 2018)	0.3	0.7	1.3	-0.6	-0.3	1.0	-0.9	0.7	-0.9	-1.1	-0.9
Depression (Nagel 2018)	0.6	0.9	1.9	-0.7	-1.4	0.9	-1.2	0.2	-1.1	0.2	-1.1
Intelligence (Savage-Jansen 2018)	0.8	2.4	4.6	-2.1	0.6	1.9	-1.9	-0.4	-1.6	0.6	-1.8
Neuroticism (Nagel 2018)	0.6	1.4	2.9	-0.6	-1.7	1.3	-1.3	-0.5	-1.2	-1.3	-1.3
Schizophrenia (2018)	0.5	1.0	3.2	0.8	0.7	-0.9	0.9	1.8	1.2	0.7	0.6
Schizophrenia vs Biploar Disorder	0.2	0.2	1.1	-0.2	0.0	0.0	0.2	-0.6	-0.2	-1.1	-0.4
Worry (Nagel 2018)	0.9	1.8	5.1	-0.8	-2.2	1.4	-1.3	-0.3	-1.2	-1.2	-1.6
Alzheimer’s Disease (in mother)	1.3	1.5	3.6	1.3	0.5	-1.4	1.6	1.9	1.2	0.6	-0.4
Alzheimer’s Disease (in father)	0.5	0.5	2.4	0.3	-1.6	-0.3	0.1	-1.0	-0.1	-0.7	-0.3
Alzheimer’s Disease (including proxy)	0.7	1.0	3.0	1.0	0.2	-1.5	1.7	0.4	0.9	-0.2	-0.4
Crohns Disease (2017)	0.6	1.4	8.5	0.4	2.9	0.1	0.4	-0.6	0.9	1.1	-0.1
Irritable Bowel Disease (IBD)	0.6	1.4	2.9	1.2	1.5	-0.6	1.1	-0.5	1.6	1.7	0.6
Ulcerative Colitis (UC)	0.5	1.0	1.8	1.0	-0.6	-0.7	1.1	-0.1	1.2	1.3	1.2
Major Depression (MDD)	0.7	0.9	4.6	-0.3	-0.5	-0.3	0.4	-2.1	0.0	-1.4	0.4
Reaction Time	1.8	3.5	6.0	2.5	1.6	-2.3	2.0	0.0	2.0	1.0	2.2
Verbal and Numeric Reasoning (VNR)	1.2	2.8	6.1	-2.5	0.0	1.8	-1.8	-1.0	-2.1	-0.7	-1.9
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	1.3	1.7	4.9	2.2	-0.1	-1.1	1.1	1.0	2.2	-0.2	0.9
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.6	0.9	3.6	0.7	1.3	-0.2	0.3	1.9	0.8	0.8	0.5
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.7	1.0	1.5	1.2	0.3	-1.1	1.2	1.1	1.0	1.2	0.4
Coronary Artery Disease (CAD)	1.9	2.2	3.3	1.8	1.2	-1.3	1.6	0.9	1.7	1.5	1.8
Crohns Disease (2012)	0.5	0.8	4.8	0.1	2.2	0.4	0.3	0.2	0.7	0.4	-0.5
Mean Putamen Volume	0.3	0.3	1.6	0.4	-0.1	-0.4	0.5	1.3	0.5	-0.6	0.1
Fasting Glucose	0.1	0.1	0.5	-0.4	-0.4	0.3	0.2	-0.3	-0.2	0.7	0.0
HbA1C	2.2	2.4	4.8	-1.4	0.5	1.9	-1.8	-1.6	-1.5	-0.8	-2.2
HDL Cholesterol	0.5	0.9	5.3	-0.0	0.5	-0.2	-0.1	-2.3	0.0	-0.9	-0.7
LDL Cholesterol	0.3	0.4	1.3	-0.6	0.3	1.1	-1.0	-0.1	-0.5	0.7	-0.4
Lupus	0.7	1.0	4.1	0.3	-1.2	-1.2	0.8	-0.4	-0.0	-2.0	0.1
Neuroticism (2016)	0.6	0.9	1.3	-0.8	-0.3	1.1	-1.0	-0.9	-1.0	1.2	-0.9
Primary Biliary Cirrhosis	0.8	1.2	2.5	1.4	-0.6	-1.0	1.2	0.3	1.4	-1.6	0.6
Rheumatoid Arthritis	0.3	0.4	1.5	0.2	1.2	0.3	-0.3	0.3	0.1	1.1	-0.0
Schizophrenia (2014)	0.5	1.2	3.1	1.4	0.8	-1.0	0.8	1.7	1.4	-0.0	0.5
Triglycerides	2.1	3.5	6.4	-2.3	-0.1	2.5	-2.0	0.3	-2.2	-1.2	-2.3
Type 2 Diabetes (T2D) (2012)	5.3	6.1	11.2	-3.3	0.0	2.6	-2.8	-1.9	-3.1	-1.2	-3.0
Ulcerative Colitis	0.2	0.3	1.8	-0.1	-0.7	0.3	0.1	-0.5	-0.1	1.3	-0.2
Blood Eosinophil Count	0.8	6.4	14.5	-2.4	0.9	3.2	-3.4	-0.9	-2.8	-0.7	-3.8
Blood Platelet Count	1.1	12.2	22.1	-3.6	-2.5	3.8	-4.5	-1.6	-4.2	-1.6	-4.7
Blood Red Count	0.3	2.8	4.8	2.0	1.8	-1.1	1.1	1.3	2.2	-1.6	2.0
Blood White Count	0.9	7.0	20.2	-2.8	-0.5	2.8	-2.9	-0.2	-2.8	-2.0	-4.5
Heel T-Score	1.4	10.9	20.6	3.6	1.4	-3.0	3.6	2.9	4.0	2.4	4.5
BMI	0.2	1.0	4.2	-1.2	0.8	0.5	-0.2	-0.3	-0.8	-2.0	-0.8
Height	1.2	22.5	143.6	3.4	12.0	-1.6	1.9	2.1	3.8	-0.1	0.6
Waist Hip Ratio (WHR)	1.5	6.8	8.6	-2.6	2.1	2.9	-2.9	-2.5	-2.5	-2.6	-2.7
Systolic Blood Pressure	2.3	11.6	17.4	-3.9	0.6	4.0	-4.2	-2.6	-3.9	-2.8	-3.7
Smoking Status	0.2	0.5	2.6	-0.2	0.7	0.3	-0.3	-0.4	-0.4	-1.6	-0.4
Allergy or Eczema	0.3	0.9	2.7	0.1	1.6	0.4	-0.5	-0.9	-0.4	1.0	-1.4
Cardiovascular Disease	1.6	5.2	7.8	-2.0	1.9	2.3	-2.1	-2.8	-1.7	-2.8	-2.3
Hypothyroidism (self reported)	1.0	2.2	4.5	1.2	1.2	-1.3	1.8	1.8	1.2	2.1	0.9
Respiratory disease	1.3	2.8	6.2	-1.5	0.6	2.3	-2.0	-1.0	-1.8	-0.9	-2.5
Type 2 Diabetes (T2D) (2018)	3.2	6.1	12.5	-3.1	1.1	2.1	-2.4	-1.1	-2.7	-3.5	-2.6
Lung FEV1/FVC ratio	2.8	14.0	24.7	-4.4	-0.7	3.1	-3.6	-1.8	-4.5	-5.0	-4.7
Lung FVC	0.9	4.7	8.7	3.0	-2.5	-2.1	2.1	0.5	2.5	0.7	2.6
Neuroticism	1.2	2.8	4.3	-1.4	-1.7	1.9	-1.7	-1.0	-2.1	-1.3	-2.0
Chronotype (morning person)	5.4	12.5	23.7	4.1	0.8	-3.8	3.9	4.9	4.0	1.8	3.2
Hair Pigment	0.0	0.6	1.6	0.6	-0.7	-0.8	0.9	-1.3	0.4	0.6	0.9
Tanning	0.0	0.6	1.3	0.9	-0.8	-1.1	1.0	0.5	0.6	0.5	0.5
Hand grip strength (left)	0.3	0.9	3.7	0.4	1.9	-0.4	0.2	-1.2	0.1	-0.9	-0.9
Number of treatments/medications taken	0.8	1.4	1.8	1.0	1.3	-0.6	1.2	1.3	1.2	1.3	1.1
Average weekly spirits intake	1.2	1.5	3.9	-1.5	0.6	2.0	-1.5	-1.1	-0.8	-0.2	-1.2
Sensitivity / hurt feelings	0.4	0.6	1.8	-0.6	-1.2	-0.0	0.1	-0.7	-0.8	-0.5	-1.4
Frequency of depressed mood in last 2 weeks	0.3	0.4	2.1	-0.3	-1.4	0.5	-0.3	-0.1	-0.3	0.8	-0.4
Hearing difficulty/problems: Yes	0.7	1.0	1.7	0.8	-0.7	-1.0	1.2	1.3	0.8	1.2	1.0
Relative age of first facial hair	0.6	1.3	2.7	-0.7	1.2	1.2	-1.1	-0.5	-0.9	-1.6	-1.3
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	1.9	1.3	-1.0	-0.7	1.1	0.8	1.4	1.0	0.8
Ever used hormone-replacement therapy (HRT)	1.3	1.7	5.2	0.8	1.1	-1.5	1.3	2.3	0.7	1.0	1.0
Ever had hysterectomy (womb removed)	0.6	0.7	3.6	0.4	-0.5	-0.8	0.5	1.9	0.0	0.3	-0.6
Systolic blood pressure, automated reading	2.9	8.3	13.6	-3.5	-0.1	3.6	-3.7	-1.1	-3.5	-2.0	-3.3
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	1.5	0.8	-0.7	-1.2	1.1	1.2	0.8	-0.1	0.5
Angina	0.9	1.2	2.3	1.5	-0.9	-1.2	1.5	-1.0	1.5	0.2	-0.1
Medication for hormone replacement therapy	2.0	2.2	6.2	-2.0	-0.6	1.2	-1.2	-0.6	-1.8	-0.8	-2.5
Vitamin and mineral supplements	0.6	0.9	3.5	0.6	1.9	-0.5	0.3	-1.0	0.6	-1.2	0.1
Supplements: Zinc	2.8	3.1	5.7	-1.3	-1.9	1.4	-1.6	-1.9	-1.7	-1.7	-2.4
Medication: Co-codamol	0.1	0.1	0.7	0.1	0.1	0.4	-0.1	0.0	0.1	0.8	0.3
Medication: Metformin	0.9	1.3	6.1	-1.4	-0.5	0.0	-0.1	-0.7	-1.0	-2.5	-0.7
Diabetes (father)	0.5	0.7	1.5	0.4	1.2	1.0	-0.4	-0.7	-0.1	-0.9	-1.0
Diabetes (mother)	0.4	0.5	1.4	-0.5	0.3	0.6	-0.3	-1.2	-0.6	-0.9	-0.6
Severe depression (siblings)	0.3	0.3	0.6	-0.6	0.2	0.5	-0.7	-0.7	-0.5	-0.5	-0.6
Pack years adult smoking proportion	1.4	2.1	4.7	-1.9	-0.4	1.6	-1.4	-2.2	-1.5	-1.4	-0.0
Impedance of leg (right)	1.0	4.7	10.5	-1.8	-0.1	3.2	-3.2	-1.3	-1.8	-1.5	-2.6
Leg fat-free mass (left)	0.8	4.1	18.1	1.4	4.3	-1.8	2.0	0.5	1.7	-1.4	0.8
Trunk fat percentage	0.7	3.0	6.8	-1.7	2.6	1.9	-1.7	-0.2	-1.4	-1.7	-1.7
Hand grip strength (right)	0.4	1.1	3.5	-0.1	1.7	-0.3	-0.1	-1.9	-0.3	-0.9	-1.1
Townsend deprivation index at recruitment	2.7	3.8	6.9	-2.1	-0.9	2.6	-2.1	-2.5	-1.9	-0.8	-2.0
Current tobacco smoking	1.2	2.0	5.1	-0.7	1.4	1.8	-1.6	0.9	-0.8	-2.3	-1.3
Average weekly fortified wine intake	0.4	0.5	1.6	0.4	0.9	-0.6	0.7	0.7	0.2	1.3	-0.2
Maternal smoking around birth	1.4	2.0	4.8	-1.1	2.2	1.4	-1.5	-0.2	-1.2	-0.3	-2.0
Fed-up feelings	0.2	0.4	0.7	-0.5	0.6	0.9	-0.6	0.4	-0.6	-0.9	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.0	-0.5	-0.6	0.5	-0.4	-0.1	-1.0	-0.4	-0.5
Relative age voice broke	0.3	0.5	1.1	-0.9	0.1	0.4	-0.7	-0.4	-1.0	-0.3	-1.1
Taking other prescription medications	1.0	1.5	3.1	1.2	0.4	-1.7	1.8	0.7	1.5	0.8	0.9
Age when periods started (menarche)	0.2	0.4	1.2	1.1	-0.5	-0.7	0.3	-0.5	0.5	-0.1	0.8
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.6	1.6	-0.2	-1.1	1.1	1.3	1.4	0.9	1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	4.7	1.5	-0.5	-1.7	2.0	0.0	1.7	0.1	2.2
Tinnitus: Yes, but not now, but have in the past	1.5	1.5	3.2	1.3	1.8	-1.0	1.3	1.0	1.2	0.7	1.3
Qualifications: CSEs or equivalent	0.1	0.1	0.5	-0.7	-0.7	0.1	0.1	0.0	-0.3	-0.2	0.1
Serious illness, injury or assault to yourself	2.3	2.8	5.2	2.3	0.3	-1.8	1.7	1.9	2.1	0.3	1.7
High blood pressure	0.5	1.4	3.1	-1.3	1.4	1.8	-1.3	-1.3	-0.8	-0.6	-0.7
Hayfever, allergic rhinitis or eczema	0.5	1.2	4.6	0.1	2.2	0.2	-0.3	-0.6	-0.1	1.7	-1.1
Multivitamins +/- minerals	1.0	1.3	2.5	-1.6	-1.0	1.2	-1.2	0.7	-1.5	0.5	-1.1
Stomach or abdominal pain in last month	0.6	0.8	2.3	-1.3	-0.4	0.7	-0.4	0.2	-0.7	-0.8	-1.5
Supplements: Glucosamine	1.2	1.6	2.9	-1.1	1.7	1.1	-1.2	-1.4	-1.3	0.7	-1.3
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	2.6	-1.0	-1.4	1.6	-1.2	-1.6	-1.1	0.2	-0.6
Medication: Atenolol	0.4	0.5	1.3	0.6	-0.6	-0.2	0.5	-0.8	0.9	1.1	0.3
Medication: Levothyroxine sodium	1.2	2.0	4.4	1.2	1.4	-1.3	1.5	2.1	1.1	1.4	1.1
Sitting height	0.4	2.6	12.2	0.1	2.3	0.4	-0.1	-0.1	0.5	-3.5	-1.8
Chronic bronchitis/emphysema (father)	0.1	0.2	0.4	-0.1	-0.0	0.4	-0.2	0.6	-0.3	0.6	-0.6
High blood pressure (mother)	0.2	0.2	0.8	-0.9	-0.0	0.5	-0.4	-0.2	-0.6	-0.4	-0.3
Body mass index (BMI)	0.2	0.9	2.9	-1.3	0.5	0.4	-0.2	-0.4	-1.0	-1.7	-0.8
Impedance of leg (left)	0.9	4.5	10.4	-1.9	-0.2	3.1	-3.2	-1.0	-1.8	-1.5	-2.5
Leg predicted mass (left)	0.7	4.0	17.3	1.4	4.2	-1.8	2.0	0.5	1.6	-1.5	0.7
Trunk fat mass	0.6	2.6	9.3	-1.2	3.0	1.3	-1.1	-0.1	-0.8	-2.1	-1.4
Waist circumference	0.8	2.8	7.6	-1.6	2.0	1.3	-1.0	-0.9	-1.4	-2.7	-1.8
Number of incorrect matches in round	0.1	0.2	0.7	0.4	-0.8	-0.5	0.6	-0.3	0.3	-0.1	0.2
Past tobacco smoking	0.2	0.5	1.0	-1.0	-0.3	0.8	-0.8	0.8	-0.4	-0.5	-0.4
Alcohol usually taken with meals	1.3	2.0	9.4	1.2	-0.5	-1.5	1.0	3.1	1.1	0.4	0.7
Nervous feelings	1.1	2.0	5.5	-1.0	-2.4	1.6	-1.7	0.5	-1.1	-0.4	-1.5
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.6	-0.5	-0.1	1.1	-0.8	-1.6	-0.9	-0.8	-0.7
Hearing difficulty/problems with background noise	0.1	0.2	1.5	0.4	-1.2	-0.2	0.0	0.0	-0.0	0.2	-0.1
Hair/balding pattern: Pattern 2	0.2	0.3	1.5	0.4	-0.1	-0.1	0.0	0.8	-0.0	1.2	0.3
Had menopause	0.7	0.9	3.9	0.3	-0.4	-0.2	0.1	2.0	-0.4	-1.6	-0.4
Had other major operations	0.2	0.2	0.5	-0.2	0.7	0.2	-0.3	0.3	0.3	0.6	0.7
Forced vital capacity (FVC)	0.3	1.2	3.3	1.8	0.7	-0.9	0.9	-0.1	1.5	-0.7	1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	3.8	1.2	-0.5	-1.6	2.0	0.3	1.6	-0.6	2.0
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	3.3	-1.3	-1.1	1.8	-1.3	-0.2	-1.1	-1.0	-1.1
Qualifications: None of the above	0.5	1.2	3.7	1.1	-1.1	-0.7	0.9	1.9	0.8	-0.3	1.1
Financial difficulties in last 2 years	0.9	1.2	3.9	-0.5	-1.0	0.9	-0.5	-0.5	-0.8	-2.0	-1.6
Mouth/teeth dental problems	0.5	0.8	1.7	-1.1	-1.0	1.1	-0.7	-1.3	-0.7	-0.1	-0.4
Heart attack	0.7	0.9	2.0	1.0	-0.4	-1.1	1.2	0.1	1.4	0.9	0.8
Allergy	0.4	1.0	4.7	-0.2	-2.2	0.1	-0.1	-0.5	-0.2	-1.5	0.9
Pain all over the body in last month	2.5	2.6	5.2	1.8	-0.4	-1.8	2.2	0.6	1.5	1.4	2.3
Diabetes (self-reported)	3.0	4.6	15.3	-2.7	-0.0	1.4	-1.7	-0.7	-2.3	-3.9	-1.9
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.7	0.6	1.3	0.1	-0.0	-0.5	0.5	0.9	0.1
Medication: Ramipril	0.3	0.4	1.3	-0.3	1.2	1.0	-0.7	0.0	-0.1	-0.6	-0.5
Medication: Simvastatin	0.3	0.5	3.4	-0.0	0.6	0.4	-0.0	-1.8	0.2	-0.4	-0.1
Fluid intelligence score	1.1	2.2	4.3	-1.3	0.9	2.1	-2.0	-0.6	-1.2	-1.0	-2.0
Illnesses of siblings	0.1	0.1	0.5	0.2	-0.1	0.2	-0.2	0.7	0.0	0.7	0.1
Neuroticism score	0.8	1.7	2.9	-1.2	-1.5	1.7	-1.4	-0.4	-1.5	-0.5	-1.5
Weight	0.5	2.3	12.4	0.1	3.5	-0.5	0.7	0.4	0.6	-2.1	-0.2
Impedance of arm (right)	0.5	2.2	5.0	-0.7	2.2	2.0	-2.2	-1.1	-0.9	0.7	-0.7
Arm fat percentage (right)	0.7	2.9	4.4	-2.0	1.0	2.1	-1.8	-1.3	-1.9	-1.7	-1.6
Trunk fat-free mass	0.5	3.0	11.5	1.2	3.4	-1.5	1.9	0.3	1.6	-1.7	0.3
Hip circumference	0.3	1.2	5.6	-0.0	2.4	-0.6	0.7	0.2	0.2	-1.7	-0.2
Time employed in main current job	0.4	0.4	2.4	-0.1	-1.6	0.5	-0.4	-0.6	-0.3	-0.4	0.1
Alcohol intake versus 10 years previously	6.0	8.9	16.1	-3.3	-0.6	4.0	-3.8	-0.6	-3.1	-2.8	-3.4
Father’s age at death	1.3	1.7	7.4	-0.8	-1.6	0.6	-0.4	1.4	-0.5	2.7	-0.4
Worrier / anxious feelings	0.4	0.8	2.6	0.8	-1.6	-0.4	0.5	1.5	0.4	0.8	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	3.7	-0.6	-0.7	0.6	-0.3	-1.9	-0.7	-1.1	-0.6
Falls in the last year	1.7	2.3	5.0	2.2	0.4	-1.4	2.0	0.8	2.1	0.3	1.6
Hair/balding pattern: Pattern 3	0.3	0.5	1.2	0.4	1.1	-0.5	0.7	-0.7	0.7	0.4	0.5
Number of live births	0.7	0.9	2.1	0.8	0.2	-1.5	1.2	1.2	0.8	-0.1	1.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	4.7	0.2	0.1	0.2	-0.3	-1.0	0.1	-2.2	-0.2
Pulse rate	0.6	0.9	2.0	1.2	-1.4	-0.7	0.5	1.2	1.0	-0.7	0.4
Happiness	1.4	1.7	3.8	-1.3	-0.3	1.1	-1.2	-1.6	-1.4	1.9	-1.0
Noisy workplace	0.4	0.5	2.1	0.1	-0.3	0.9	-0.3	1.4	0.2	-1.0	0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.8	-0.5	0.3	0.1	-0.2	-1.4	-0.4	0.7	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.4	0.0	-0.1	0.4	0.0	0.3	0.3	-0.3	-1.2
Mouth/teeth dental problems: Dentures	0.3	0.4	1.1	0.5	1.0	-0.8	0.5	1.0	0.1	0.4	-0.3
Asthma	1.1	2.1	5.8	-1.2	1.2	1.9	-1.6	-0.3	-1.3	-0.5	-2.4
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.3	0.1	1.1	1.1	-0.7	0.4	0.2	-0.9	-0.3
Medication: Cholesterol lowering	0.1	0.2	0.6	-0.3	0.2	0.3	0.0	-0.8	-0.0	-0.4	-0.5
Depression (self-reported)	1.1	1.3	3.6	0.9	-1.9	-0.9	1.2	1.0	1.1	-0.8	1.0
Medication: Lansoprazole	0.7	0.8	2.3	-0.8	-1.5	0.9	-0.6	-0.9	-1.0	-0.3	-0.7
Prospective memory result	1.7	2.1	3.8	1.8	0.7	-1.3	1.6	1.8	1.9	0.9	1.1
Lung cancer (father)	0.6	0.7	2.2	-0.9	-0.3	0.5	-0.4	-0.7	-0.9	-1.5	-0.8
Illnesses of mother	0.2	0.2	0.5	-0.4	-0.7	0.3	-0.7	-0.6	-0.1	-0.1	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.8	0.8	0.2	-0.3	0.2	0.3	0.6	-1.3	0.3
Pulse wave Arterial Stiffness index	1.6	1.8	3.5	-1.6	0.6	1.7	-1.9	-0.4	-1.5	-0.9	-1.5
Impedance of arm (left)	0.3	1.5	7.5	0.5	2.7	0.7	-1.1	0.1	0.4	1.4	0.1
Arm fat mass (right)	0.6	2.5	6.8	-1.6	1.8	1.3	-1.0	-0.7	-1.3	-2.6	-1.4
Trunk predicted mass	0.5	2.9	11.2	1.2	3.4	-1.5	1.8	0.4	1.6	-1.6	0.3
Standing height	1.0	10.0	49.1	2.9	7.0	-1.8	1.8	1.8	3.2	-1.4	0.9
Length of working week for main job	1.8	2.0	3.5	1.9	1.6	-1.5	1.7	0.7	1.8	-0.4	0.9
Exposure to tobacco smoke at home	0.2	0.3	1.8	-0.0	-0.3	0.1	0.0	-0.1	-0.2	-1.4	-0.5
Breastfed as a baby	2.1	2.6	5.3	1.6	-1.2	-1.4	1.9	0.7	2.0	1.2	2.3
Tense / ‘highly strung’	0.1	0.2	0.4	0.6	0.5	-0.1	0.1	-0.5	0.5	0.1	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	0.9	-0.9	-0.6	0.9	-0.5	-0.3	-0.6	0.2	0.2
Hair/balding pattern: Pattern 4	1.6	3.9	6.8	-2.2	0.8	2.1	-2.2	-0.4	-2.4	-1.9	-2.6
Birth weight of first child	0.2	0.4	0.9	0.3	0.6	-0.8	0.9	0.0	0.5	0.8	0.8
Peak expiratory flow (PEF)	0.5	1.3	5.6	-0.5	-0.9	0.3	-0.8	-0.4	-0.7	-2.4	-1.4
Pulse wave reflection index	2.1	2.6	5.2	-2.3	1.1	1.8	-2.0	-1.4	-1.9	-0.1	-1.3
Ever highly irritable/argumentative for 2 days	2.1	2.5	5.0	-1.6	1.5	1.5	-1.6	-0.7	-1.7	-1.5	-2.2
Loud music exposure frequency	0.8	0.9	3.0	-0.7	-0.5	0.8	-0.4	-0.9	-0.5	-1.7	-1.3
Qualifications: O levels/GCSEs or equivalent	2.7	4.2	7.3	-2.1	1.0	1.8	-2.0	-2.7	-2.0	-1.6	-2.7
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	2.9	-1.0	0.1	1.7	-1.6	-0.7	-1.1	-1.2	-1.6
Blood clot in the leg (DVT)	0.6	0.8	1.5	1.0	0.0	-1.0	0.9	0.6	1.2	0.7	1.0
Medication: Paracetamol	0.7	1.2	6.6	-0.0	1.1	1.1	-0.8	2.6	0.3	0.4	-0.1
Headache pain in last month	0.2	0.3	0.8	-0.4	0.8	0.8	-0.5	-0.1	-0.4	-0.9	-0.3
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.9	0.2	-0.3	-0.2	-0.2	0.9	-0.2	0.9	0.4
Glaucoma (self-reported)	0.3	0.4	0.8	-0.3	0.1	0.7	-0.8	-0.7	-0.3	0.9	-0.6
Gout (self-reported)	0.1	0.1	0.3	-0.1	-0.4	-0.6	0.5	-0.1	0.2	-0.2	0.1
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	2.4	0.9	1.5	-1.1	1.6	0.5	1.0	1.2	1.2
Medication: Amlodipine	0.5	0.7	1.1	-0.8	-0.7	1.0	-1.0	0.5	-0.6	-1.0	-0.7
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.6	-0.7	1.3	0.1	-0.2	-1.1	-0.5	0.5	-0.6
Birth weight	0.1	0.3	1.3	-0.0	1.1	-0.6	0.5	-0.2	-0.1	0.7	-0.1
Chronic bronchitis/emphysema (mother)	1.2	1.4	6.8	-0.6	2.6	0.5	-0.5	-0.7	-1.0	-0.9	-0.9
High blood pressure (siblings)	0.1	0.2	0.9	-0.2	0.0	0.2	0.0	-0.9	0.2	0.6	0.6
Forced vital capacity (FVC), Best measure	0.7	2.4	5.3	2.3	1.2	-1.5	1.5	1.0	2.0	0.2	1.8
Body fat percentage	0.8	3.1	4.3	-2.0	1.6	2.1	-1.9	-0.5	-1.7	-2.0	-1.8
Leg fat percentage (right)	1.0	3.6	5.8	-2.4	0.1	2.2	-2.0	-1.0	-2.0	-2.3	-2.1
Arm fat-free mass (right)	0.8	3.9	9.8	1.5	3.1	-2.0	2.4	1.5	1.9	-1.9	0.6
Exposure to tobacco smoke outside home	0.2	0.3	1.6	-0.3	-0.2	0.5	-0.4	-0.1	-0.3	-1.3	-0.7
Comparative body size at age 10	3.0	8.2	15.6	2.5	0.6	-3.0	3.3	1.8	2.5	4.0	3.8
Number of full brothers	0.4	0.5	1.5	0.5	-1.2	-0.0	-0.1	0.9	-0.0	-0.9	0.6
Worry too long after embarrassment	0.6	1.1	5.3	0.4	-2.3	-0.7	0.8	0.3	0.2	0.7	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	4.3	1.9	-1.8	-1.2	1.4	1.3	1.7	0.6	2.1
Wheeze or whistling in the chest in last year	0.4	0.8	4.5	0.4	2.1	0.5	-0.3	0.8	0.5	0.4	-0.3
Number of children fathered	0.1	0.1	0.3	0.2	-0.1	-0.2	0.5	-0.1	0.3	0.4	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	3.8	-0.0	-0.0	0.0	0.0	1.9	-0.1	0.4	0.4
Age at first live birth	0.8	1.4	6.0	-0.6	-2.5	1.3	-1.1	-0.7	-0.4	0.9	-0.1
Pulse wave peak to peak time	1.3	1.6	3.1	1.6	-0.3	-1.6	1.8	0.2	1.5	0.4	1.4
Health satisfaction	1.0	1.3	1.9	-1.2	0.5	1.3	-1.1	-1.4	-1.1	1.1	-1.3
Shortness of breath walking on level ground	1.5	1.8	4.0	1.7	0.1	-0.9	1.2	-0.7	1.6	2.0	1.6
Qualifications: College or University degree	0.1	0.3	1.3	0.2	0.8	-1.2	0.7	0.1	0.1	0.3	-0.0
Eye problems/disorders: None of the above	0.3	0.3	0.7	-0.5	0.7	0.7	-0.5	-0.9	-0.6	0.1	0.2
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.7	-0.8	-0.9	0.6	-1.3	0.7	-0.9	-1.1	-0.8
Emphysema/chronic bronchitis	3.6	4.1	8.4	2.6	0.1	-2.1	2.5	0.7	2.9	-0.1	2.6
Medication for pain relief, constipation, heartburn	0.4	0.7	2.5	0.1	-0.6	-1.2	0.8	-1.6	-0.1	0.8	0.5
Neck or shoulder pain in last month	0.3	0.4	1.2	-0.7	-0.7	0.5	-0.1	-0.6	-0.4	-1.1	-0.0
Medication: Blood pressure	0.1	0.2	0.5	0.1	0.4	-0.2	0.7	0.3	0.7	-0.7	0.2
Angina (self-reported)	0.9	1.1	1.9	1.4	-1.0	-1.2	1.4	-0.9	1.3	-0.1	-0.1
Migraine (self-reported)	0.2	0.3	0.9	0.1	-0.2	-0.4	0.6	0.1	0.9	-0.1	0.9
Medication: Ibuprofen	0.7	0.8	2.1	-0.5	1.3	1.4	-1.0	-0.5	-0.3	-0.9	-0.5
Medication: Allopurinol	0.7	1.0	2.0	0.6	0.1	-1.2	1.4	1.1	1.1	0.5	1.0
Medication: Omeprazole	0.2	0.2	0.7	-0.4	-0.8	0.0	0.2	0.4	-0.2	0.7	-0.2
Medication: Seretide 50 evohaler	0.5	0.6	2.9	0.8	0.8	0.0	0.3	0.2	0.6	1.7	0.4
Mean time to correctly identify matches	2.3	4.3	7.5	2.7	0.8	-2.4	2.3	1.4	2.1	1.7	2.4
Heart disease (mother)	0.2	0.3	1.3	-0.2	0.5	-0.3	0.2	-0.5	-0.2	1.1	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.8	3.7	-0.9	1.9	0.7	-0.4	0.7	-0.3	-0.3	-0.6
Whole body fat mass	0.7	2.8	7.1	-1.6	2.2	1.5	-1.3	-0.5	-1.2	-2.7	-1.7
Leg fat mass (right)	0.6	2.4	8.0	-1.5	1.6	1.3	-1.0	-0.4	-1.1	-2.8	-1.6
Arm predicted mass (right)	0.7	3.7	8.1	1.6	2.8	-2.0	2.4	1.2	2.0	-1.9	0.6
Pulse rate, automated reading	0.2	0.5	1.2	-0.6	0.2	0.8	-0.7	0.8	-0.5	-1.1	-0.9
Alcohol intake frequency.	0.5	1.1	4.0	-0.4	-0.4	0.1	0.1	2.0	-0.5	-1.9	-0.8
Comparative height size at age 10	1.4	7.6	20.9	3.2	4.6	-2.0	2.1	2.1	3.6	1.0	1.7
Number of full sisters	1.6	2.0	6.1	-1.7	-1.0	1.0	-1.1	-1.2	-1.6	-2.5	-0.4
Suffer from ‘nerves’	0.4	0.6	3.0	-0.4	-1.7	0.7	-0.5	0.4	-0.6	-0.1	0.1
Overall health rating	0.2	0.4	1.5	-0.1	1.2	-0.0	0.6	-0.7	0.4	-0.7	0.3
Chest pain or discomfort	0.3	0.4	1.5	0.8	0.4	-0.4	0.6	-0.2	1.2	-0.3	0.7
Had major operations	0.5	0.6	1.5	-0.9	0.3	0.6	-0.5	-0.3	-0.6	-1.2	-1.1
Age at last live birth	0.5	0.7	2.5	0.1	-1.6	-0.1	0.4	-0.7	0.5	1.1	0.8
Family relationship satisfaction	0.6	0.8	1.5	-1.0	-0.0	0.8	-0.7	-1.1	-1.1	0.5	-1.2
Leg pain on walking	2.3	2.9	6.8	-1.6	-2.6	1.4	-1.1	-2.3	-1.4	-1.2	-1.3
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	3.3	-0.9	0.1	0.6	-0.3	-1.8	-0.5	-0.8	-0.4
Commuting to job workplace: Car/motor vehicle	3.5	4.0	6.7	2.1	2.2	-2.6	2.4	0.5	2.2	0.3	2.2
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	1.8	-1.3	0.2	0.9	-1.3	-1.2	-1.0	0.2	-0.4
Medication: Aspirin	0.8	1.0	2.6	1.0	-1.0	-1.3	1.6	-0.0	1.0	-0.4	0.8
Supplements: Vitamin C	0.9	1.0	1.8	-1.3	-1.0	1.1	-0.5	-0.6	-1.1	-1.0	-1.3
Knee pain experienced in last month	0.4	0.6	1.9	-1.1	0.3	1.4	-0.6	-0.5	-0.6	-0.3	-0.6
Hypertension (Self-reported)	0.7	2.0	4.1	-1.6	1.1	2.0	-1.6	-1.7	-1.1	-1.0	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	2.3	-0.4	1.5	0.2	-0.1	-0.1	-0.0	1.0	-0.2
Illnesses of father: Heart disease	1.2	1.7	3.2	1.8	1.2	-1.4	1.5	1.0	1.5	0.2	1.3
Illnesses of siblings: Diabetes	0.6	0.7	3.8	-0.6	-0.5	0.2	-0.2	-1.9	-0.6	-0.7	-0.6
Smoking status: Previous	0.6	0.8	1.9	0.9	-0.0	-1.4	1.3	-0.9	0.4	0.9	0.8
Forced expiratory volume in 1-second (FEV1), predicted	2.0	4.1	27.2	1.5	5.2	-0.9	0.2	0.2	1.6	-0.0	0.2
Whole body fat-free mass	0.7	3.8	13.9	1.4	3.7	-1.9	2.1	0.5	1.7	-1.8	0.5
Leg fat-free mass (right)	0.9	4.7	16.4	1.8	4.0	-2.2	2.4	0.6	1.9	-1.2	1.2
Arm fat percentage (left)	0.4	1.4	1.9	-1.4	1.2	1.3	-1.1	-0.8	-1.2	-1.4	-1.1
Average weekly red wine intake	0.2	0.2	1.0	0.2	-1.0	-0.4	0.1	-0.8	0.1	0.0	-0.3
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.2	-0.9	-0.2	0.7	-0.8	-1.1	-0.9	-0.2	-1.0
Mood swings	0.1	0.2	1.1	0.0	-0.5	0.3	0.2	1.0	0.2	-0.1	0.1
Loneliness, isolation	0.3	0.5	2.1	-0.1	-0.0	0.9	-0.8	-1.4	-0.4	0.2	0.2
Long-standing illness, disability or infirmity	0.0	0.1	0.2	-0.1	-0.3	-0.2	0.5	-0.2	0.2	-0.4	-0.1
Ever had bowel cancer screening	1.3	1.5	3.6	-1.4	-1.5	0.8	-0.7	-0.7	-1.6	1.9	-0.2
Diabetes diagnosed by doctor	2.3	3.8	11.1	-2.5	-0.1	1.5	-1.6	-1.3	-1.9	-3.3	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	7.5	1.4	2.7	-1.2	1.3	0.6	1.1	-0.0	0.8
Friendships satisfaction	1.0	1.3	2.2	1.5	1.0	-1.2	1.1	0.1	1.5	0.8	1.2
Qualifications: nursing, teaching	0.2	0.3	0.8	-0.4	0.9	-0.5	0.3	-0.8	-0.5	-0.7	0.0
Commuting to job workplace: Walk	0.3	0.3	1.3	0.6	-1.1	0.1	0.1	0.0	0.9	0.3	-0.0
Eye problems/disorders: Cataract	0.6	0.8	3.8	0.2	-1.9	-0.3	0.3	0.7	0.2	-1.2	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.4	0.3	-1.1	-0.5	0.5	-0.3	0.1	0.8	1.2
Medication for cholesterol	0.6	1.0	2.3	1.5	-0.6	-1.5	1.1	0.1	0.9	-0.0	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	2.2	-1.3	1.5	1.0	-1.0	-0.4	-0.7	-0.7	-1.1
Back pain experienced in last month	0.2	0.3	0.9	0.2	0.8	-0.4	0.5	0.9	0.5	-0.5	0.2
Mineral and other dietary supplements	3.3	4.4	9.8	2.4	0.9	-3.1	2.7	0.4	2.3	-0.3	2.5
Breast cancer (self-reported)	0.8	0.9	4.7	-0.2	-2.2	-0.3	0.3	0.7	0.2	0.9	1.0
Asthma (self-reported)	1.3	2.7	7.4	-1.4	1.0	2.0	-1.8	-0.8	-1.6	-0.6	-2.7
Osteoporosis (self-reported)	0.9	1.1	6.7	0.6	0.0	-0.0	0.2	2.6	0.6	1.2	0.1
Osteoarthritis (self-reported)	0.1	0.1	0.8	-0.3	0.9	0.1	0.1	0.2	-0.2	-0.0	-0.5
Medication: Aspirin	0.8	1.0	2.6	1.1	-0.7	-1.3	1.6	-0.3	1.2	-0.2	1.0
Medication: Gliclazide	0.8	0.9	3.1	-1.1	-0.3	0.6	-0.7	1.0	-0.7	-1.8	-0.8
Illnesses of father: None of the above (group 1)	0.3	0.4	0.9	-0.9	-0.9	-0.1	-0.2	-0.2	-0.5	-0.8	-0.8
Smoking status: Current	1.2	1.9	5.2	-0.8	0.9	1.9	-1.7	0.4	-0.9	-2.3	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.2	6.4	1.2	-2.5	-1.4	1.1	1.7	1.1	-0.4	1.4
Whole body water mass	0.7	4.0	13.8	1.5	3.7	-1.9	2.2	0.7	1.8	-1.7	0.6
Leg predicted mass (right)	0.8	4.5	16.1	1.7	4.0	-2.2	2.3	0.6	1.8	-1.2	1.2
Arm fat mass (left)	0.4	1.6	4.9	-1.2	1.8	0.9	-0.6	-0.3	-0.9	-2.2	-1.1
Number of self-reported non-cancer illnesses	0.5	0.8	4.5	-0.7	2.1	1.0	-0.7	-0.3	-0.0	0.1	-0.4
Average weekly champagne plus white wine intake	0.3	0.4	2.2	0.4	-0.0	0.1	-0.2	-1.5	-0.4	-0.1	-0.5
Miserableness	1.2	2.0	4.1	-2.0	-0.1	1.5	-1.5	-0.3	-2.0	-1.3	-1.4
Guilty feelings	1.1	1.6	3.6	-0.8	-1.2	1.8	-1.2	0.6	-1.1	1.9	-0.9
Wears glasses or contact lenses	0.5	0.6	2.4	-0.0	-1.5	-0.6	0.4	0.9	-0.5	0.7	-0.2
Ever taken oral contraceptive pill	4.6	5.1	12.2	-2.3	-0.2	2.6	-2.2	-3.5	-2.0	-1.6	-2.3
Hearing aid user	0.2	0.3	1.4	-0.5	-1.2	0.1	0.2	-0.3	-0.4	-0.3	0.4
Mother’s age at death	0.2	0.2	0.7	-0.2	0.2	-0.8	0.6	-0.1	-0.2	-0.7	-0.0
Financial situation satisfaction	5.0	6.2	9.3	-3.0	-0.7	2.5	-2.5	-3.0	-2.6	-2.2	-2.5
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.2	-1.0	1.5	0.6	-0.5	1.4	-0.4	-0.3	-0.7
Commuting to job workplace: Public transport	1.3	1.6	2.8	-1.7	-0.9	1.0	-1.2	-0.9	-1.6	-1.6	-0.8
Eye problems/disorders: Glaucoma	0.1	0.2	0.4	0.0	0.5	-0.1	-0.3	-0.6	0.0	0.5	-0.5
Medication: Blood pressure	0.2	0.3	0.8	-0.9	0.2	0.9	-0.7	-0.5	-0.6	0.1	0.3
Pain type(s) experienced in last month: Hip pain	0.6	0.8	3.2	-0.6	0.3	1.4	-0.6	0.2	-0.3	-1.8	-0.2
Supplements: Fish oil (including cod liver oil)	2.8	3.7	9.4	-2.2	-0.3	3.1	-2.6	-0.2	-1.9	0.0	-2.1
High cholesterol (Self-reported)	0.5	1.0	2.0	-1.0	-0.7	1.4	-1.1	-1.0	-0.8	-0.4	-1.1
Medication: Bendroflumethiazide	0.2	0.2	0.5	0.2	0.7	0.4	-0.4	-0.6	0.5	-0.3	0.5
Medication: Paracetamol	1.4	2.1	7.2	1.5	1.1	-0.3	0.6	2.7	1.6	0.8	1.6
Medication: Lisinopril	0.6	0.8	1.9	0.8	-0.5	-0.9	1.2	-0.2	0.7	0.7	1.4
Medication: Atorvastatin	0.2	0.2	0.6	-0.4	-0.5	0.5	-0.3	0.7	-0.4	-0.3	-0.5
Illnesses of father: High blood pressure	1.1	1.4	5.1	1.0	2.3	-0.8	0.9	0.8	1.1	-0.2	1.2
Alcohol drinker status: Never	0.3	0.4	1.2	-0.4	-0.2	-1.1	1.1	-0.5	-0.2	0.7	-0.0
Ever smoked	0.4	0.6	1.6	1.2	0.5	-0.9	1.0	-0.2	0.7	0.5	0.8
Basal metabolic rate	0.6	3.3	14.0	1.0	3.7	-1.4	1.6	0.3	1.3	-2.1	0.2
Leg fat percentage (left)	1.0	3.5	6.1	-2.5	-0.0	2.2	-2.0	-0.8	-2.1	-2.1	-2.0
Arm fat-free mass (left)	0.4	2.0	6.8	0.2	2.6	-0.7	1.1	0.8	0.5	-2.6	-0.5
Number of operations (self-reported)	0.4	0.6	3.3	-0.9	-0.7	0.0	0.0	1.8	-0.4	-0.2	-0.3
Average weekly beer plus cider intake	0.1	0.2	0.5	-0.2	0.1	0.7	-0.5	-0.7	-0.0	-0.3	-0.0
Irritability	4.8	8.2	12.9	-2.7	-1.1	3.6	-3.6	-2.9	-2.9	-2.0	-3.2
Risk taking	0.6	0.9	3.0	0.6	0.1	-0.7	1.0	0.7	0.7	-1.7	1.0
Ever had prostate specific antigen (PSA) test	0.6	0.7	3.4	-0.5	-1.3	-0.2	-0.1	-1.9	-0.4	0.1	0.4
Fractured/broken bones in last 5 years	0.2	0.2	0.8	-0.5	-0.2	-0.0	-0.2	-0.7	-0.9	-0.5	-0.2
Age started oral contraceptive pill	0.4	0.5	2.6	-0.6	-0.3	-0.5	0.5	1.6	-0.2	-0.6	0.1
Diastolic blood pressure, automated reading	0.4	1.1	2.8	-0.9	-0.2	0.8	-0.8	-1.2	-1.1	-1.7	-1.0
Ever depressed for a whole week	1.7	2.0	5.4	-1.6	0.1	1.4	-1.6	0.4	-1.7	-1.0	-2.3
Unable to work because of sickness or disability	0.2	0.3	0.7	-0.5	-0.5	0.4	-0.6	0.0	-0.7	-0.8	-0.2
Commuting to job workplace: Cycle	0.5	0.6	1.5	1.2	0.1	-0.7	0.7	0.4	1.0	0.9	0.5
Myopia	0.4	0.5	0.8	0.9	0.9	-0.7	0.9	0.7	0.7	0.2	0.8
Vascular/heart problems diagnosed by doctor	0.1	0.4	1.1	0.4	-1.0	-0.8	0.3	1.1	-0.1	0.1	0.1
Cholesterol lowering medication	0.2	0.3	0.8	0.6	-0.7	-0.1	0.4	-0.7	0.5	0.3	0.9
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.2	-0.5	-0.8	-0.0	0.3	0.6	-0.1	1.1	-0.0
Pain experienced in last month	0.5	0.8	3.5	0.6	-1.4	-0.5	-0.0	-0.6	-0.1	1.9	0.6
Supplements: Calcium	0.8	0.8	3.5	-0.4	0.4	0.8	-0.9	1.9	-0.4	1.0	-0.5
Basal cell carcinoma (self-reported)	2.0	2.3	3.9	-2.0	-0.9	1.5	-1.6	-1.6	-1.8	-1.5	-0.8
Heart attack/myocardial infarction (self-reported)	0.7	1.0	2.5	1.1	-0.4	-1.1	1.3	0.1	1.6	0.6	0.7
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.0	0.7	-0.1	-0.7	0.7	0.4	1.0	0.9	0.9
Heart disease (siblings)	0.3	0.4	0.7	0.5	-0.6	-0.9	0.6	-0.7	0.2	-0.7	0.2
Alcohol drinker status: Previous	0.3	0.4	2.3	-0.0	-0.2	-0.3	0.3	1.5	-0.5	-0.3	-0.4
Pack years of smoking	0.8	1.2	3.9	-1.4	-0.3	1.1	-0.9	-2.0	-1.1	-0.7	0.3
Impedance of whole body	0.3	1.5	4.6	-0.6	1.5	1.9	-2.2	-0.1	-0.6	0.2	-1.0
Leg fat mass (left)	0.6	2.3	7.3	-1.5	1.6	1.3	-1.0	-0.3	-1.1	-2.7	-1.6
Arm predicted mass (left)	0.4	2.2	7.1	0.4	2.7	-0.8	1.2	0.7	0.8	-2.6	-0.4