TWAS hub - KIAA0174

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0597	0.0226	1.4e-06	0.018	0.014	0.011	0.014	0.008	1.5e-06	2.3e-05	1.1e-04	1.4e-05	7.3e-04
2	TCGA	Brain Lower Grade Glioma	0.0555	0.0300	2.4e-06	0.063	0.054	0.052	NA	0.057	1.2e-07	8.0e-07	1.4e-06	NA	4.0e-07
3	TCGA	Thyroid Carcinoma	0.0380	0.0210	4.0e-04	0.048	0.041	0.043	NA	0.046	1.6e-05	7.0e-05	4.4e-05	NA	2.7e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Ever taken oral contraceptive pill	8.3	9.2	10.0	-3.2	-2.9	-3.0
Alcohol intake frequency.	8.0	18.5	22.6	3.2	4.8	4.8
Falls in the last year	7.6	10.3	13.0	-2.3	-3.6	-3.6
Ever smoked	7.3	12.7	16.3	-2.5	-3.9	-4.0
Financial difficulties in last 2 years	6.4	8.7	8.9	-2.9	-3.0	-3.0
Fasting Glucose	6.0	7.2	12.4	3.5	1.9	2.4
Qualifications: College or University degree	6.0	19.0	25.4	-2.5	-5.0	-5.0
Heart disease (siblings)	5.8	7.2	12.3	3.5	2.1	2.1
Alcohol intake versus 10 years previously	5.4	8.0	9.5	2.3	3.1	3.1
Mineral and other dietary supplements	5.2	6.9	8.5	-2.1	-2.8	-2.9
Medication: Levothyroxine sodium	4.8	8.1	9.1	-2.5	-3.0	-3.0
Ever unenthusiastic/disinterested for a whole week	4.8	5.9	7.0	-2.6	-2.3	-2.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.8	10.2	11.4	3.1	3.1	3.4
Supplements: Fish oil (including cod liver oil)	4.7	6.1	7.0	2.4	2.4	2.6
Smoking Status	4.6	10.9	15.2	-3.9	-2.9	-3.0
Past tobacco smoking	4.5	8.3	10.3	2.2	3.1	3.2
Ever used hormone-replacement therapy (HRT)	4.3	5.5	7.5	-2.7	-2.1	-2.1
Lung FVC	4.2	21.5	29.2	5.4	4.2	4.2
High cholesterol (Self-reported)	4.2	7.5	11.2	3.4	2.4	2.4
Length of working week for main job	4.0	4.4	5.9	-1.2	-2.4	-2.4
Gout (self-reported)	4.0	5.4	6.5	-1.9	-2.5	-2.5
Ever depressed for a whole week	4.0	4.9	9.8	-3.1	-1.6	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	3.9	9.0	10.9	2.7	3.0	3.3
Smoking status: Current	3.9	6.2	11.4	-3.4	-1.9	-1.9
Forced vital capacity (FVC), Best measure	3.8	13.8	15.5	3.4	3.8	3.9
Medication: Ibuprofen (e.g. Nurofen)	3.6	4.6	7.9	-2.8	-1.8	-1.6
Mouth/teeth dental problems: Bleeding gums	3.6	4.7	5.0	-2.0	-2.2	-2.2
Bipolar Disorder (2018)	3.5	5.6	6.5	-2.0	-2.6	-2.5
Commuting to job workplace: Public transport	3.5	4.2	5.7	-2.4	-1.9	-1.8
Risk taking	3.5	5.1	6.8	-1.6	-2.6	-2.4
LDL Cholesterol	3.4	5.5	8.1	2.9	2.0	2.0
Serious illness, injury or assault to yourself	3.4	4.1	4.2	-2.0	-2.0	-2.0
Average weekly red wine intake	3.4	5.1	5.9	-1.9	-2.4	-2.4
Forced vital capacity (FVC)	3.3	12.5	13.2	3.5	3.5	3.6
Qualifications: None of the above	3.3	7.0	10.3	0.7	3.2	3.2
Illness, injury, bereavement, stress in last 2 years	3.3	4.0	4.8	2.2	1.9	1.9
Heel bone mineral density (BMD) T-score, automated (left)	3.2	7.3	7.9	2.8	2.5	2.8
Eye problems/disorders: Glaucoma	3.2	3.8	5.9	0.5	2.3	2.4
Current tobacco smoking	3.1	5.1	9.9	-3.1	-1.7	-1.7
Basal cell carcinoma (self-reported)	3.1	3.7	5.3	2.3	1.6	1.8
Medication for hormone replacement therapy	3.0	3.4	3.7	-1.8	-1.9	-1.8
Birth weight of first child	3.0	5.5	13.1	-3.6	-1.3	-1.3
Medication for pain relief, constipation, heartburn	3.0	5.1	11.9	3.4	1.3	1.3
Medication: Ibuprofen	3.0	3.5	5.2	-2.3	-1.7	-1.6
Fractured/broken bones in last 5 years	3.0	3.9	4.5	-1.7	-2.1	-2.1
Chronotype (morning person)	2.9	6.8	8.8	1.8	3.0	2.9
Medication: Allopurinol	2.9	3.8	4.4	-1.7	-2.0	-2.1
Ulcerative Colitis	2.8	4.1	5.0	-1.7	-2.1	-2.2
Birth weight	2.7	5.9	6.9	-2.1	-2.6	-2.5
Blood Red Count	2.6	25.0	54.9	7.4	3.1	3.2
Cholesterol lowering medication	2.6	3.8	6.7	2.6	1.6	1.5
Chronic bronchitis/emphysema (father)	2.5	3.0	4.2	0.9	2.1	2.0
Depression (self-reported)	2.5	3.0	3.1	-1.7	-1.8	-1.7
Mother’s age at death	2.5	3.2	4.2	1.3	2.0	1.9
Age when periods started (menarche)	2.4	5.9	6.3	2.4	2.4	2.5
Medication: Omeprazole	2.4	2.9	6.3	-2.5	-1.1	-1.1
Ulcerative Colitis (UC)	2.3	4.3	4.5	-2.1	-2.0	-2.1
Severe depression (siblings)	2.3	2.5	5.0	-2.2	-1.2	-1.1
Medication: Aspirin	2.3	3.1	3.5	-1.6	-1.9	-1.8
Hearing aid user	2.3	2.6	3.1	1.3	1.7	1.8
Hearing difficulty/problems: Yes	2.2	3.4	3.7	1.9	1.8	1.8
Supplements: Zinc	2.2	2.4	2.6	1.5	1.6	1.6
Ever had prostate specific antigen (PSA) test	2.2	2.5	5.3	2.3	1.0	1.0
Alzheimer’s Disease (including proxy)	2.1	3.1	3.8	1.5	1.9	1.8
HDL Cholesterol	2.1	3.4	5.2	0.1	-2.3	-2.3
Health satisfaction	2.1	2.8	3.9	-0.8	-1.9	-2.0
Emphysema/chronic bronchitis	2.1	2.4	3.8	0.5	2.0	1.8
Heel T-Score	2.0	16.1	22.4	4.7	3.4	3.8
Qualifications: A levels/AS levels or equivalent	2.0	4.5	6.4	-1.1	-2.5	-2.5
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.3	2.5	1.4	1.5	1.6
Wears glasses or contact lenses	2.0	2.3	3.0	-1.0	-1.7	-1.7
Prostate Cancer	1.9	2.6	3.3	1.2	1.8	1.8
Mouth/teeth dental problems: Dentures	1.9	3.2	4.1	1.4	2.0	1.9
Back pain experienced in last month	1.9	2.7	3.5	1.3	1.8	1.9
Bipolar Disorder or Schizophrenia	1.8	4.3	5.8	-1.3	-2.4	-2.4
Lung FEV1/FVC ratio	1.8	9.3	11.1	-3.3	-3.0	-2.8
Vitamin and mineral supplements	1.8	2.4	3.0	-1.2	-1.7	-1.7
Glaucoma (self-reported)	1.8	2.1	3.3	-0.4	1.7	1.8
Schizophrenia vs Biploar Disorder	1.7	2.3	3.3	1.8	1.3	1.3
Primary Biliary Cirrhosis	1.7	2.4	3.0	-1.7	-1.4	-1.5
Time employed in main current job	1.7	2.0	2.7	0.9	1.6	1.6
Forced expiratory volume in 1-second (FEV1)	1.7	5.6	6.5	2.5	2.2	2.4
Hypothyroidism/myxoedema (self-reported)	1.7	3.3	3.7	-1.9	-1.7	-1.8
Miserableness	1.7	2.9	3.4	-1.8	-1.6	-1.7
Intelligence (Savage-Jansen 2018)	1.6	4.9	7.5	-0.5	-2.6	-2.7
Average weekly fortified wine intake	1.6	1.8	2.4	-1.5	-1.3	-1.2
Exposure to tobacco smoke outside home	1.6	2.2	2.4	-1.5	-1.5	-1.4
Chest pain or discomfort	1.6	2.3	2.9	-1.1	-1.7	-1.7
Guilty feelings	1.6	2.4	3.3	0.9	1.8	1.8
Medication: Bendroflumethiazide	1.6	2.5	3.5	-1.1	-1.7	-1.9
Crohns Disease (2017)	1.5	3.3	4.9	0.8	2.1	2.2
Major Depression (MDD)	1.5	1.8	2.0	-1.2	-1.4	-1.4
Pack years adult smoking proportion	1.5	2.4	5.4	-2.3	-1.0	-0.8
Sitting height	1.5	10.4	11.1	3.2	3.1	3.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.8	5.5	2.1	2.1	2.3
Pulse wave peak to peak time	1.5	1.7	2.2	0.9	1.5	1.5
Long-standing illness, disability or infirmity	1.5	2.3	2.5	-1.5	-1.5	-1.6
Medication: Lisinopril	1.5	2.0	3.4	-1.9	-1.0	-1.2
Multivitamins +/- minerals	1.4	1.7	2.0	1.2	1.3	1.4
Alcohol usually taken with meals	1.4	2.3	3.5	-1.9	-1.3	-1.3
Pain all over the body in last month	1.4	1.5	1.7	1.2	1.2	1.3
Neck or shoulder pain in last month	1.4	2.0	3.2	0.1	1.7	1.8
Alcohol drinker status: Never	1.4	1.6	2.4	0.7	1.5	1.4
Neuroticism (2016)	1.3	1.9	2.7	-1.6	-1.1	-1.3
Rheumatoid Arthritis	1.3	1.7	5.2	2.3	-0.1	-0.1
Tinnitus: Yes, but not now, but have in the past	1.3	1.3	1.7	-1.3	-1.1	-1.1
Headache pain in last month	1.3	2.2	5.9	-2.4	-0.5	-0.7
Pain type(s) experienced in last month: Hip pain	1.3	1.6	1.9	1.2	1.4	1.2
Number of operations (self-reported)	1.3	2.0	4.0	-2.0	-1.1	-0.9
Heart attack/myocardial infarction (self-reported)	1.3	1.7	2.0	-1.4	-1.3	-1.2
Pack years of smoking	1.3	1.9	4.2	-2.1	-0.9	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	2.4	0.5	1.6	1.4
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	1.8	-0.9	-1.4	-1.2
Pulse wave Arterial Stiffness index	1.2	1.4	1.7	-1.0	-1.3	-1.3
Illnesses of siblings: Diabetes	1.2	1.4	2.5	0.1	-1.6	-1.4
Ever had bowel cancer screening	1.2	1.5	2.3	0.3	1.5	1.4
Bipolar Disorder (2011)	1.1	1.1	1.6	0.4	1.2	1.3
Maternal smoking around birth	1.1	1.6	2.6	0.4	1.5	1.6
Had menopause	1.1	1.4	1.6	1.0	1.3	1.2
Arm fat percentage (right)	1.1	4.3	6.2	-2.5	-1.8	-1.9
Happiness	1.1	1.3	2.1	-1.4	-1.0	-1.0
Family relationship satisfaction	1.1	1.4	2.0	0.5	1.4	1.4
Smoking status: Previous	1.1	1.6	2.2	-0.9	-1.4	-1.5
Osteoporosis (self-reported)	1.1	1.4	1.8	-1.0	-1.1	-1.4
Diastolic blood pressure, automated reading	1.1	3.4	5.4	-0.5	-2.1	-2.3
Type 2 Diabetes (T2D) (2012)	1.0	1.2	2.1	-1.4	-0.9	-0.8
Number of treatments/medications taken	1.0	1.8	3.6	-1.9	-0.9	-1.0
Relative age of first facial hair	1.0	2.0	3.6	-1.9	-1.0	-1.2
Fluid intelligence score	1.0	2.0	4.6	2.1	-0.9	-0.9
Prospective memory result	1.0	1.2	1.8	0.1	1.3	1.3
Number of full brothers	1.0	1.3	1.5	1.0	1.2	1.1
Leg pain on walking	1.0	1.3	2.1	0.2	-1.4	-1.4
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	2.3	0.5	1.5	1.5
Illnesses of father: None of the above (group 1)	1.0	1.2	1.9	-0.3	-1.4	-1.2
Hand grip strength (left)	0.9	2.4	3.1	1.2	1.8	1.7
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	1.9	-0.2	-1.3	-1.4
Arm fat mass (right)	0.9	3.6	5.2	-2.3	-1.6	-1.7
Arm fat percentage (left)	0.9	3.4	4.6	-2.1	-1.6	-1.8
Loneliness, isolation	0.9	1.2	1.3	1.1	1.2	0.9
Osteoarthritis (self-reported)	0.9	1.1	1.7	1.3	0.8	1.0
Illnesses of father: High blood pressure	0.9	1.2	1.9	-0.3	-1.2	-1.4
Triglycerides	0.8	1.4	2.1	-0.1	1.4	1.4
Tanning	0.8	9.5	12.7	1.8	3.6	3.5
Diabetes (father)	0.8	1.0	1.1	-1.0	-1.1	-1.0
Waist circumference	0.8	2.8	2.9	-1.7	-1.6	-1.7
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	2.0	-0.4	1.4	1.3
Illnesses of siblings	0.8	1.1	2.3	-1.5	-0.6	-0.7
Worrier / anxious feelings	0.8	1.4	1.9	0.8	1.4	1.3
Tense / ‘highly strung’	0.8	1.4	2.7	-1.6	-0.7	-1.0
Mean time to correctly identify matches	0.8	1.6	3.6	1.9	0.8	0.7
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.0	1.4	-0.5	-0.7
Vascular/heart problems diagnosed by doctor	0.8	2.1	2.4	1.2	1.6	1.5
Ovarian Cancer	0.7	0.9	1.2	-0.6	-1.1	-1.1
Impedance of leg (right)	0.7	3.3	4.5	1.5	2.1	1.8
Hayfever, allergic rhinitis or eczema	0.7	1.4	2.1	1.4	1.1	0.9
Heart attack	0.7	0.9	1.4	-1.2	-0.9	-0.8
Medication: Ramipril	0.7	0.9	1.3	-1.2	-0.9	-0.7
Number of children fathered	0.7	0.7	1.7	1.3	0.6	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.2	1.5	0.3	0.4
Diabetes diagnosed by doctor	0.7	1.1	1.7	0.6	-1.2	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.0	-0.5	-1.0	-0.9
Medication for cholesterol	0.7	1.1	2.4	1.6	0.6	0.6
Medication: Aspirin	0.7	0.9	1.3	-0.6	-1.1	-1.1
Arm fat mass (left)	0.7	2.8	4.1	-2.0	-1.4	-1.4
Number of self-reported non-cancer illnesses	0.7	1.2	1.6	-0.8	-1.2	-1.3
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	2.7	-1.6	0.1	0.1
Alzheimer’s Disease (in father)	0.6	0.6	1.3	1.1	0.6	0.5
Verbal and Numeric Reasoning (VNR)	0.6	1.4	2.6	1.6	-0.9	-0.9
Schizophrenia (2014)	0.6	1.3	2.1	0.0	-1.4	-1.4
Hypothyroidism (self reported)	0.6	1.5	1.7	-1.3	-1.1	-1.3
Diabetes (mother)	0.6	0.8	2.4	1.5	0.2	0.1
Townsend deprivation index at recruitment	0.6	0.9	2.1	-1.4	-0.5	-0.6
Relative age voice broke	0.6	1.0	1.6	-1.3	0.9	0.7
Impedance of leg (left)	0.6	2.7	3.7	1.3	1.9	1.6
Diabetes (self-reported)	0.6	1.0	1.5	0.6	-1.0	-1.2
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	1.6	-0.1	1.3	1.2
Worry too long after embarrassment	0.6	1.1	1.3	0.9	1.2	1.1
Mouth/teeth dental problems: Loose teeth	0.6	0.7	0.8	-0.7	-0.9	-0.9
Heart disease (mother)	0.6	0.7	1.9	1.4	0.2	0.2
Leg fat-free mass (right)	0.6	3.2	4.2	-2.1	-1.8	-1.5
Leg predicted mass (right)	0.6	3.2	4.2	-2.1	-1.8	-1.5
Irritability	0.6	1.0	2.9	-1.7	0.1	0.1
Depression (Nagel 2018)	0.5	0.8	1.2	-0.1	1.1	1.1
Reaction Time	0.5	1.0	2.9	1.7	0.4	0.3
Crohns Disease (2012)	0.5	0.8	1.1	0.4	1.0	1.1
BMI	0.5	3.2	4.1	-2.0	-1.6	-1.6
Systolic Blood Pressure	0.5	2.3	6.8	2.6	0.2	-0.1
Leg fat-free mass (left)	0.5	2.8	4.2	-2.0	-1.6	-1.3
High blood pressure	0.5	1.4	1.6	-1.1	-1.3	-1.3
Body mass index (BMI)	0.5	2.2	2.2	-1.5	-1.4	-1.5
Leg predicted mass (left)	0.5	2.8	4.2	-2.0	-1.6	-1.4
Hip circumference	0.5	2.1	2.5	-1.6	-1.4	-1.3
Number of live births	0.5	0.7	0.9	0.6	1.0	0.9
Pulse rate	0.5	0.8	1.0	-0.6	-0.9	-1.0
Noisy workplace	0.5	0.6	1.6	-1.3	0.2	0.2
Lung cancer (father)	0.5	0.6	0.8	0.4	0.9	0.9
Exposure to tobacco smoke at home	0.5	0.5	0.8	-0.4	0.8	0.9
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.3	1.1	0.4	0.5
Medication: Ventolin 100micrograms inhaler	0.5	0.6	0.9	0.3	1.0	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	1.4	-1.2	-0.5	-0.4
Wheeze or whistling in the chest in last year	0.5	0.9	1.4	0.4	1.0	1.2
Migraine (self-reported)	0.5	0.6	1.0	-1.0	-0.6	-0.6
Comparative height size at age 10	0.5	2.9	8.7	-3.0	-0.0	0.2
Had major operations	0.5	0.6	1.3	-1.1	-0.6	-0.5
Mood swings	0.5	0.9	2.5	-1.6	-0.2	-0.2
Friendships satisfaction	0.5	0.7	0.9	0.5	-1.0	-0.9
Financial situation satisfaction	0.5	0.6	0.8	-0.6	-0.9	-0.8
Medication: Blood pressure	0.5	0.9	1.4	-1.2	-0.8	-0.9
Alzheimer’s Disease (in mother)	0.4	0.5	0.8	-0.1	0.9	0.7
Mean Putamen Volume	0.4	0.4	0.5	0.7	0.6	0.6
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.3	1.1	-0.5	-0.7
Neuroticism	0.4	1.1	1.3	-1.1	-0.9	-1.1
Number of incorrect matches in round	0.4	0.6	1.4	-1.2	-0.4	-0.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	0.9	0.9	-0.5	-0.6
Weight	0.4	2.0	3.3	-1.8	-1.2	-1.1
Hair/balding pattern: Pattern 3	0.4	0.7	1.2	1.1	0.6	0.6
Comparative body size at age 10	0.4	1.2	1.4	-1.0	1.1	1.2
Hypertension (Self-reported)	0.4	1.1	1.3	-0.8	-1.1	-1.1
Illnesses of father: Heart disease	0.4	0.5	1.6	-1.2	0.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	2.3	-1.5	0.0	-0.1
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.3	1.1	-0.2	-0.3
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.3	-1.2	-0.2	-0.3
Schizophrenia (2018)	0.3	0.7	1.1	0.0	-1.0	-1.1
HbA1C	0.3	0.3	0.9	-0.0	0.9	0.1
Blood White Count	0.3	2.0	2.7	0.7	1.6	1.6
Waist Hip Ratio (WHR)	0.3	1.5	1.9	-0.9	-1.3	-1.4
Allergy or Eczema	0.3	0.7	0.9	0.7	0.9	0.8
Frequency of depressed mood in last 2 weeks	0.3	0.5	0.8	-0.9	0.6	0.5
Systolic blood pressure, automated reading	0.3	0.8	1.5	1.2	-0.4	-0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.5	0.7	-0.5	-0.5
Medication: Co-codamol	0.3	0.3	0.4	-0.6	0.5	0.5
Medication: Metformin	0.3	0.4	0.6	0.8	0.5	0.4
Mouth/teeth dental problems	0.3	0.4	0.7	0.1	-0.8	-0.8
Trunk predicted mass	0.3	1.5	3.5	-1.9	-0.8	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.8	-0.9	-0.6	-0.4
Pulse wave reflection index	0.3	0.3	0.5	-0.1	-0.7	-0.7
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.7	0.4	-0.9	-0.8
Medication: Amlodipine	0.3	0.4	1.1	-1.1	-0.3	-0.3
Eye problems/disorders: None of the above	0.3	0.3	0.7	0.8	0.4	0.4
Age at last live birth	0.3	0.5	0.6	-0.8	-0.6	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.4	0.4	-0.6	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.5	-0.7	0.5	0.5
Whole body fat-free mass	0.3	1.7	3.4	-1.8	-1.1	-0.7
Medication: Gliclazide	0.3	0.3	0.5	-0.7	-0.4	-0.5
Whole body water mass	0.3	1.7	3.2	-1.8	-1.1	-0.8
Medication: Atorvastatin	0.3	0.3	0.7	-0.0	-0.5	-0.9
Basal metabolic rate	0.3	1.9	3.5	-1.9	-1.1	-0.9
Age started oral contraceptive pill	0.3	0.4	0.7	-0.2	0.8	0.7
Pain experienced in last month	0.3	0.5	0.7	0.0	-0.9	-0.9
Supplements: Calcium	0.3	0.3	0.5	-0.1	-0.5	-0.7
Alcohol drinker status: Previous	0.3	0.4	0.6	-0.3	0.7	0.8
Impedance of whole body	0.3	1.4	1.9	1.0	1.4	1.1
Breast Cancer	0.2	0.4	0.7	-0.3	-0.8	-0.6
Age at First Birth	0.2	0.3	0.4	-0.3	-0.6	-0.6
Body Mass Index (BMI) (2010)	0.2	0.2	0.7	-0.8	0.0	-0.0
Coronary Artery Disease (CAD)	0.2	0.2	0.6	-0.8	0.2	0.4
Blood Eosinophil Count	0.2	1.5	2.0	0.8	1.4	1.4
Cardiovascular Disease	0.2	0.6	1.6	1.3	-0.4	-0.3
Respiratory disease	0.2	0.4	0.5	-0.7	0.5	0.7
Sensitivity / hurt feelings	0.2	0.3	0.6	-0.1	0.8	0.7
Ever had hysterectomy (womb removed)	0.2	0.2	0.3	0.5	0.4	0.4
Angina	0.2	0.3	0.4	-0.2	-0.5	-0.7
Trunk fat percentage	0.2	0.7	1.6	-1.3	-0.4	-0.5
Fed-up feelings	0.2	0.4	1.3	-1.1	-0.0	-0.1
Taking other prescription medications	0.2	0.3	0.4	-0.3	-0.6	-0.6
Trunk fat mass	0.2	0.8	1.9	-1.4	-0.4	-0.5
Had other major operations	0.2	0.2	0.6	0.8	0.1	0.3
Allergy	0.2	0.5	0.5	-0.7	-0.7	-0.6
Medication: Simvastatin	0.2	0.3	0.3	0.6	0.5	0.6
Neuroticism score	0.2	0.4	0.6	-0.8	0.7	0.4
Trunk fat-free mass	0.2	1.2	3.1	-1.8	-0.7	-0.4
Father’s age at death	0.2	0.2	0.2	-0.4	0.5	0.5
Peak expiratory flow (PEF)	0.2	0.5	1.4	1.2	0.2	0.4
Medication: Paracetamol	0.2	0.3	0.7	-0.9	0.3	0.2
Body fat percentage	0.2	0.8	1.6	-1.2	-0.5	-0.7
Leg fat percentage (right)	0.2	0.7	0.8	-0.9	-0.6	-0.9
Shortness of breath walking on level ground	0.2	0.2	0.4	-0.1	-0.4	-0.7
Whole body fat mass	0.2	1.0	2.1	-1.5	-0.6	-0.7
Leg fat mass (right)	0.2	0.9	1.4	-1.2	-0.8	-0.9
Pulse rate, automated reading	0.2	0.6	0.9	0.4	-0.9	-0.9
Overall health rating	0.2	0.5	0.6	-0.7	0.8	0.7
Knee pain experienced in last month	0.2	0.3	0.5	-0.7	0.3	0.4
Commuting to job workplace: Walk	0.2	0.2	0.6	-0.8	-0.3	0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.4	0.1	-0.5	-0.6
Leg fat percentage (left)	0.2	0.9	1.2	-1.1	-0.7	-0.9
Average weekly beer plus cider intake	0.2	0.2	0.3	-0.4	0.5	0.5
Leg fat mass (left)	0.2	0.9	1.5	-1.2	-0.8	-0.8
Depressed Affect (Nagel 2018)	0.1	0.3	0.5	-0.7	-0.3	-0.4
Neuroticism (Nagel 2018)	0.1	0.1	0.2	-0.5	-0.1	-0.4
Irritable Bowel Disease (IBD)	0.1	0.2	0.5	-0.7	-0.1	-0.0
Lupus	0.1	0.1	0.2	-0.3	0.3	0.4
Height	0.1	1.8	3.1	-0.6	1.4	1.8
Average weekly spirits intake	0.1	0.2	0.5	-0.7	-0.0	0.0
Stomach or abdominal pain in last month	0.1	0.1	0.3	-0.6	0.0	-0.1
Supplements: Glucosamine	0.1	0.1	0.2	0.4	-0.1	-0.0
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	-0.0	-0.4	-0.5
Medication: Atenolol	0.1	0.1	0.1	-0.0	-0.3	-0.4
High blood pressure (mother)	0.1	0.2	0.3	-0.5	-0.2	-0.4
Hearing difficulty/problems with background noise	0.1	0.2	0.3	-0.1	-0.5	-0.5
Hair/balding pattern: Pattern 2	0.1	0.1	0.2	0.4	-0.1	-0.1
Impedance of arm (right)	0.1	0.4	0.8	-0.9	-0.2	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.2	-0.3	-0.4	-0.3
Asthma	0.1	0.1	0.4	-0.6	-0.1	0.0
Medication: Cholesterol lowering	0.1	0.2	0.5	-0.7	-0.1	0.0
Medication: Lansoprazole	0.1	0.1	0.1	-0.0	0.3	0.4
Illnesses of mother	0.1	0.1	0.2	-0.1	-0.5	-0.4
Standing height	0.1	0.8	1.0	-0.9	0.7	1.0
Loud music exposure frequency	0.1	0.1	0.2	-0.5	-0.2	-0.0
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.3	0.5	-0.2	-0.2
High blood pressure (siblings)	0.1	0.1	0.2	-0.2	-0.4	-0.5
Arm fat-free mass (right)	0.1	0.3	0.8	-0.9	-0.2	0.0
Age at first live birth	0.1	0.2	0.4	0.0	-0.6	-0.6
Medication: Blood pressure	0.1	0.3	0.6	-0.8	-0.3	-0.3
Angina (self-reported)	0.1	0.1	0.2	-0.1	-0.4	-0.5
Medication: Seretide 50 evohaler	0.1	0.1	0.2	-0.5	0.2	0.2
Arm predicted mass (right)	0.1	0.3	0.8	-0.9	-0.2	0.1
Number of full sisters	0.1	0.1	0.2	-0.0	-0.4	-0.4
Suffer from ‘nerves’	0.1	0.2	0.4	-0.6	0.5	0.2
Supplements: Vitamin C	0.1	0.1	0.1	-0.1	0.4	0.4
Qualifications: nursing, teaching	0.1	0.2	0.3	0.5	-0.4	-0.5
Breast cancer (self-reported)	0.1	0.1	0.2	0.4	0.3	0.3
Asthma (self-reported)	0.1	0.1	0.2	-0.4	0.3	0.5
Average weekly champagne plus white wine intake	0.1	0.2	0.3	0.1	-0.4	-0.5
Medication: Paracetamol	0.1	0.1	0.4	-0.6	-0.0	0.0
Arm fat-free mass (left)	0.1	0.7	1.6	-1.2	-0.6	-0.3
Unable to work because of sickness or disability	0.1	0.2	0.2	0.4	0.5	0.3
Commuting to job workplace: Cycle	0.1	0.1	0.2	-0.0	0.2	0.4
Myopia	0.1	0.1	0.2	-0.2	-0.4	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	0.2	0.4	0.4
Arm predicted mass (left)	0.1	0.6	1.3	-1.1	-0.6	-0.3
Worry (Nagel 2018)	0.0	0.0	0.1	0.1	-0.0	-0.3
Blood Platelet Count	0.0	0.5	1.3	-1.2	-0.1	-0.2
Hair Pigment	0.0	0.2	0.5	0.7	-0.2	-0.1
Hand grip strength (right)	0.0	0.1	0.1	0.1	0.3	0.3
Qualifications: CSEs or equivalent	0.0	0.1	0.1	0.4	-0.1	-0.1
Nervous feelings	0.0	0.0	0.1	0.3	-0.0	-0.2
Impedance of arm (left)	0.0	0.1	0.3	-0.6	0.0	-0.1
Breastfed as a baby	0.0	0.0	0.1	-0.3	0.1	0.1
Hair/balding pattern: Pattern 4	0.0	0.0	0.1	-0.3	0.1	0.2
Blood clot in the leg (DVT)	0.0	0.0	0.0	-0.0	-0.0	-0.0
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.2	0.1	-0.2	-0.4
Eye problems/disorders: Cataract	0.0	0.0	0.0	0.1	0.1	0.2

Hub : Genes

KIAA0174

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Trait associations