Hub : Genes

KIAA0930

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.167	0.0380	1.2e-07	0.136	0.069	0.147	0.141	0.145	3.3e-16	8.6e-09	1.8e-17	9.1e-17	2.6e-17
2	GTEx	Artery Tibial	0.335	0.0609	1.6e-07	0.213	NA	0.184	NA	0.231	1.3e-16	NA	2.4e-14	NA	5.1e-18
3	GTEx	Cells Transformed fibroblasts	0.238	0.0610	1.7e-04	0.157	NA	0.111	NA	0.143	7.8e-12	NA	1.1e-08	NA	7.8e-11
4	GTEx	Esophagus Mucosa	0.179	0.0600	3.1e-03	0.077	NA	0.052	NA	0.071	7.4e-06	NA	2.1e-04	NA	1.7e-05
5	GTEx	Esophagus Muscularis	0.299	0.0580	7.6e-07	0.186	NA	0.219	NA	0.217	1.7e-11	NA	2.1e-13	NA	2.8e-13
6	GTEx	Heart Atrial Appendage	0.216	0.0700	3.3e-03	0.025	NA	0.049	NA	0.044	2.7e-02	NA	2.9e-03	NA	4.7e-03
7	GTEx	Muscle Skeletal	0.408	0.0447	0.0e+00	0.356	NA	0.330	NA	0.341	2.3e-36	NA	3.7e-33	NA	1.5e-34
8	GTEx	Small Intestine Terminal Ileum	0.495	0.1400	6.7e-03	-0.002	NA	0.018	NA	-0.004	3.5e-01	NA	1.3e-01	NA	4.0e-01
9	GTEx	Whole Blood	0.166	0.0580	3.6e-03	-0.002	NA	0.015	NA	0.002	6.4e-01	NA	1.4e-02	NA	2.0e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.6	0.9	6.9	0.2	0.1	-2.6	-0.0	-0.2	0.8	0.4	0.4	0.6
Bipolar Disorder or Schizophrenia	0.8	1.8	4.0	-1.1	1.7	-0.3	0.9	1.3	1.5	1.9	-2.0	-0.5
Depressed Affect (Nagel 2018)	1.4	2.9	5.4	2.1	-2.3	0.7	-1.9	-2.1	-1.0	-2.2	-1.3	-0.7
Depression (Nagel 2018)	1.3	2.0	3.3	1.2	-1.8	0.4	-1.5	-1.6	-0.8	-1.7	-1.8	-1.2
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.7	0.6	-0.6	-0.3	-0.4	-0.3	0.1	-0.6	1.3	-0.7
Neuroticism (Nagel 2018)	1.0	2.3	4.3	2.0	-2.1	0.8	-1.8	-1.9	0.4	-1.8	-1.3	0.1
Schizophrenia (2018)	1.6	3.4	8.3	-1.7	2.1	1.7	1.1	1.8	1.3	2.1	-2.9	-1.4
Schizophrenia vs Biploar Disorder	0.4	0.6	2.1	-0.7	0.4	1.4	-0.0	0.3	-0.5	0.4	-0.8	-1.1
Worry (Nagel 2018)	0.8	1.7	2.1	1.4	-1.5	0.7	-1.3	-1.4	1.3	-1.2	-1.2	1.4
Alzheimer’s Disease (in mother)	0.9	1.1	2.5	-1.3	1.0	-0.6	1.1	1.1	1.6	0.7	1.1	-0.2
Alzheimer’s Disease (in father)	0.7	0.7	5.5	-0.5	0.4	-0.5	0.2	0.4	0.0	0.2	-2.4	-0.5
Alzheimer’s Disease (including proxy)	1.0	1.5	2.7	-1.6	1.1	-1.2	1.3	1.4	1.6	0.9	-0.6	-0.9
Crohns Disease (2017)	0.1	0.3	0.7	-0.2	0.4	-0.8	0.8	0.5	-0.4	0.4	-0.8	-0.4
Irritable Bowel Disease (IBD)	0.2	0.5	2.4	-0.3	0.4	-1.0	0.7	0.5	0.5	0.3	-1.5	-0.3
Ulcerative Colitis (UC)	0.3	0.5	1.4	-0.3	0.3	-1.1	0.5	0.5	1.2	0.1	-0.9	-0.1
Major Depression (MDD)	0.6	0.7	2.0	1.4	-0.7	-0.3	-0.5	-0.8	0.9	-0.9	-0.9	0.8
Reaction Time	0.2	0.4	0.7	-0.8	0.9	0.9	0.2	0.5	-0.5	0.7	-0.1	0.4
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.4	-0.6	0.5	-0.2	0.7	0.7	0.3	0.5	1.2	-0.0
Breast Cancer	0.9	2.1	6.4	-1.2	1.2	-2.5	1.8	1.3	-0.8	1.1	1.6	0.4
Ovarian Cancer	1.2	1.5	5.3	0.7	-1.1	2.3	-1.1	-0.8	-1.0	-0.9	1.7	0.6
Prostate Cancer	0.6	0.9	6.2	-0.4	-0.0	2.5	-0.3	-0.1	-0.4	0.0	-0.5	-1.1
Age at First Birth	0.6	0.9	2.5	-0.2	0.9	-1.1	1.2	0.9	1.6	1.0	0.2	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.4	0.5	3.1	0.3	-0.2	-1.8	-0.4	-0.3	-0.9	-0.4	-0.3	-0.4
Coronary Artery Disease (CAD)	0.7	0.9	1.5	-0.9	1.1	1.2	0.9	1.0	0.7	1.1	0.8	0.3
Crohns Disease (2012)	0.1	0.2	0.5	-0.3	0.3	-0.1	0.4	0.3	-0.7	0.1	0.7	-0.6
Mean Putamen Volume	1.3	1.5	2.8	-1.4	1.5	0.8	1.6	1.2	-1.0	1.7	-0.9	0.4
Fasting Glucose	0.8	0.9	3.3	-0.2	0.3	-1.8	0.2	0.3	-0.1	0.3	1.5	-1.5
HbA1C	1.1	1.2	4.2	2.1	-0.9	-0.1	-1.4	-1.5	0.5	-0.6	0.0	-0.8
HDL Cholesterol	0.3	0.5	2.4	1.1	-0.1	0.7	0.1	-0.3	0.2	-0.0	0.1	1.6
LDL Cholesterol	1.9	2.9	6.2	2.1	-2.2	0.7	-2.5	-2.3	-0.8	-2.1	-0.1	-0.5
Lupus	0.4	0.6	1.7	-1.0	0.4	-0.9	0.5	0.5	1.1	0.3	-1.3	0.4
Neuroticism (2016)	1.7	2.4	3.8	-1.7	1.8	-0.6	1.7	1.8	1.9	1.9	-0.1	1.4
Primary Biliary Cirrhosis	0.5	0.7	1.5	1.0	-0.6	0.6	-0.7	-0.7	-0.4	-0.8	-0.9	-1.2
Rheumatoid Arthritis	2.9	3.9	7.1	2.5	-2.5	1.5	-2.4	-2.7	-1.1	-2.4	-0.1	-0.9
Schizophrenia (2014)	1.0	2.1	8.8	-1.2	1.5	0.8	0.5	1.0	1.3	1.7	-3.0	-0.4
Triglycerides	0.1	0.2	0.6	0.3	-0.6	-0.0	-0.3	-0.3	-0.0	-0.5	-0.8	-0.7
Type 2 Diabetes (T2D) (2012)	1.5	1.8	5.1	1.3	-1.2	1.1	-1.2	-1.3	-2.3	-1.2	0.7	-1.3
Ulcerative Colitis	0.4	0.5	2.3	-0.7	0.6	-0.5	0.7	0.8	1.5	0.4	-0.2	0.0
Blood Eosinophil Count	0.1	0.6	2.4	-0.3	-0.1	-0.9	-0.2	0.1	0.8	-0.3	-1.5	-1.1
Blood Platelet Count	0.5	5.4	8.4	2.5	-2.6	1.5	-2.9	-2.6	-1.9	-2.6	-1.8	-2.1
Blood Red Count	0.1	1.3	3.6	1.4	-0.8	0.5	-0.5	-0.7	1.7	-1.0	0.7	1.9
Blood White Count	0.4	3.2	6.8	1.3	-1.9	-0.3	-1.9	-1.9	-1.9	-1.8	-1.6	-2.6
Heel T-Score	0.6	4.4	7.3	2.7	-2.4	-0.2	-2.2	-2.3	0.2	-2.4	-1.8	-2.7
BMI	0.2	1.4	6.4	1.0	-1.1	-0.3	-0.7	-0.7	-0.9	-1.2	-1.1	-2.5
Height	0.4	7.9	16.1	-3.4	3.8	-1.0	4.0	3.6	0.4	3.7	0.5	1.1
Waist Hip Ratio (WHR)	0.4	1.9	6.6	-1.7	1.0	1.3	1.1	1.3	1.1	1.0	-2.6	0.4
Systolic Blood Pressure	0.1	0.7	4.2	0.2	-0.5	2.1	-0.9	-0.2	0.6	-0.4	-0.1	-0.5
Smoking Status	0.0	0.0	0.2	0.1	-0.3	-0.0	-0.4	0.0	-0.2	-0.1	-0.1	-0.1
Allergy or Eczema	0.3	0.8	3.5	0.6	-0.6	-0.2	-1.0	-0.7	0.8	-0.5	-1.9	-0.6
Cardiovascular Disease	0.3	0.9	2.8	-0.8	0.5	1.5	0.0	0.7	0.8	0.5	-1.7	-0.7
Hypothyroidism (self reported)	0.5	1.1	4.8	-0.2	0.3	-0.9	0.5	0.3	0.1	0.2	-2.0	-2.2
Respiratory disease	1.0	2.2	4.9	1.8	-1.9	1.3	-1.7	-1.7	-0.6	-2.2	-0.0	0.4
Type 2 Diabetes (T2D) (2018)	0.5	0.8	5.5	0.0	-0.1	1.1	-0.5	-0.1	0.4	0.1	-2.4	-0.7
Lung FEV1/FVC ratio	0.5	2.6	10.3	1.2	-1.1	-1.2	-0.7	-1.2	-2.2	-1.2	-1.0	-3.2
Lung FVC	0.7	3.5	6.8	-1.7	2.5	-1.1	2.4	2.2	1.9	2.6	-0.1	0.9
Neuroticism	0.1	0.3	1.2	0.6	-0.5	-0.3	-0.3	-0.3	0.6	-0.4	-0.4	1.1
Chronotype (morning person)	0.6	1.4	2.5	0.9	-1.2	1.6	-1.2	-1.5	-1.1	-1.3	-0.7	-0.9
Hair Pigment	0.0	0.9	6.8	-0.0	-0.1	-0.9	-0.2	0.4	2.6	-0.1	-0.2	0.7
Tanning	1.0	12.0	40.4	1.9	-2.2	0.4	-1.9	-2.8	-6.4	-2.9	1.4	-6.1
Hand grip strength (left)	0.7	1.7	10.7	-0.0	0.2	-3.3	0.3	0.4	1.3	0.2	-0.4	1.7
Number of treatments/medications taken	2.0	3.7	6.1	1.8	-2.5	1.8	-2.4	-2.2	-1.2	-2.4	-0.5	-1.6
Average weekly spirits intake	0.3	0.3	1.0	0.6	-0.4	0.6	-0.3	-0.5	0.1	-0.4	1.0	0.8
Sensitivity / hurt feelings	0.7	1.2	5.4	0.8	-1.0	0.6	-1.1	-1.0	-2.3	-0.8	-0.3	-0.9
Frequency of depressed mood in last 2 weeks	4.8	6.7	10.3	3.1	-3.2	-0.4	-3.0	-3.2	-1.3	-3.2	-3.1	-0.4
Hearing difficulty/problems: Yes	0.9	1.3	2.4	-1.3	1.2	-1.5	1.5	1.2	0.3	1.1	-1.0	0.3
Relative age of first facial hair	0.8	1.6	10.1	-0.2	0.7	-0.6	0.8	0.8	-0.1	0.8	1.0	3.2
Other serious medical condition/disability diagnosed by doctor	2.0	2.6	8.9	1.8	-1.3	3.0	-1.5	-1.2	-1.1	-1.1	-1.0	-1.6
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.5	0.5	-0.5	0.8	-0.4	-0.6	-0.4	-0.7	1.0	-1.6
Ever had hysterectomy (womb removed)	0.6	0.7	2.2	-1.5	0.8	0.7	0.7	0.8	0.0	0.8	-0.1	-1.1
Systolic blood pressure, automated reading	0.5	1.3	3.2	-0.9	0.8	1.3	0.7	1.1	1.2	0.8	1.8	-1.2
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.1	-1.3	1.4	0.7	1.1	1.1	0.6	1.4	0.8	0.7
Angina	0.2	0.3	1.7	-0.6	0.3	1.3	0.1	0.6	0.1	0.1	-0.6	0.2
Medication for hormone replacement therapy	0.7	0.7	1.5	-0.8	0.8	-1.1	0.7	0.6	1.2	0.9	0.8	-0.6
Vitamin and mineral supplements	1.1	1.5	3.0	1.0	-1.2	1.7	-1.6	-1.2	-0.9	-1.1	-0.9	1.3
Supplements: Zinc	0.1	0.1	0.2	0.0	-0.4	-0.4	0.1	-0.2	-0.1	-0.3	-0.4	-0.0
Medication: Co-codamol	0.3	0.3	2.0	0.2	-0.4	-0.1	0.1	-0.1	-0.6	-0.7	-0.0	-1.4
Medication: Metformin	1.1	1.5	4.3	1.3	-1.0	1.2	-1.4	-1.3	0.7	-1.0	-2.1	0.0
Diabetes (father)	0.3	0.4	1.9	0.0	0.3	0.0	0.7	0.2	-0.2	-0.0	-0.7	-1.4
Diabetes (mother)	1.1	1.4	2.6	-1.6	1.2	-1.3	1.4	1.4	0.7	1.1	-0.6	0.8
Severe depression (siblings)	0.5	0.5	1.6	0.7	-0.2	1.2	-0.4	-0.3	-0.7	0.0	-1.3	-0.8
Pack years adult smoking proportion	0.5	0.8	4.6	-0.2	0.0	-0.1	-0.1	0.3	-0.4	0.1	-2.1	1.6
Impedance of leg (right)	0.6	2.7	8.0	-1.4	1.4	-0.2	0.9	1.3	2.1	1.5	-1.8	2.8
Leg fat-free mass (left)	0.4	2.0	3.5	1.6	-1.6	-0.1	-1.0	-1.4	-1.9	-1.9	-0.6	-1.5
Trunk fat percentage	0.5	2.0	5.9	1.4	-1.5	1.4	-1.5	-1.4	-0.5	-1.5	-2.4	0.1
Hand grip strength (right)	0.6	1.5	9.2	0.2	-0.2	-3.0	-0.2	-0.0	0.9	-0.1	-0.2	1.9
Townsend deprivation index at recruitment	1.2	1.7	3.0	1.4	-1.4	0.9	-1.5	-1.4	-0.7	-1.5	-1.7	0.7
Current tobacco smoking	0.4	0.7	1.4	0.6	-0.8	0.2	-1.1	-0.5	-1.0	-0.7	-1.0	-1.2
Average weekly fortified wine intake	0.6	0.8	2.4	0.8	-0.7	1.5	-0.8	-0.4	0.8	-0.7	1.1	0.4
Maternal smoking around birth	1.8	2.6	4.5	2.1	-1.9	-1.0	-2.1	-2.0	-1.7	-1.8	-0.5	-0.3
Fed-up feelings	1.8	3.3	6.2	2.3	-2.5	0.2	-2.0	-2.2	-1.4	-2.4	-1.1	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.8	4.7	1.8	-2.2	-0.2	-1.8	-2.1	-1.9	-2.1	-0.6	-1.1
Relative age voice broke	0.1	0.2	1.0	0.3	0.1	-0.7	0.4	0.0	-1.0	0.1	0.1	0.5
Taking other prescription medications	0.2	0.2	0.7	0.4	-0.6	0.2	-0.3	-0.3	0.4	-0.7	-0.1	-0.8
Age when periods started (menarche)	0.6	1.4	4.0	1.4	-1.3	0.1	-0.9	-1.4	-2.0	-1.5	-0.2	0.4
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.7	0.5	-0.8	0.8	-1.0	-1.1	-1.0	-0.7	-0.3	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	2.6	1.6	-1.3	-0.8	-1.5	-1.3	0.0	-1.2	-1.4	-1.0
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	1.8	-1.2	1.1	-1.0	0.7	0.8	-0.0	1.4	-0.1	-0.8
Qualifications: CSEs or equivalent	0.9	1.2	3.5	0.8	-1.0	-0.1	-1.3	-1.5	-1.9	-0.9	0.7	0.5
Serious illness, injury or assault to yourself	0.8	0.9	3.9	0.4	-0.4	1.6	-0.6	-0.6	-2.0	-0.6	-0.2	0.2
High blood pressure	0.7	1.8	5.7	0.7	-1.1	2.4	-1.4	-1.0	-1.2	-1.1	-1.2	-1.4
Hayfever, allergic rhinitis or eczema	0.5	1.1	6.5	-0.2	0.2	-1.6	-0.0	0.1	0.4	0.3	-2.5	-0.0
Multivitamins +/- minerals	0.3	0.4	2.3	-0.0	0.2	-1.5	0.6	0.1	0.0	0.0	0.3	-1.1
Stomach or abdominal pain in last month	0.5	0.7	4.6	0.8	-0.4	0.4	0.1	-0.4	-0.2	-0.4	-2.1	-0.4
Supplements: Glucosamine	1.1	1.5	2.9	-0.7	1.6	-0.6	1.7	1.4	1.7	1.5	-0.2	-0.2
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	1.6	-0.3	0.2	-0.3	0.2	0.1	-0.0	0.1	-1.3	0.6
Medication: Atenolol	1.5	1.9	4.8	1.0	-1.3	2.2	-1.4	-1.1	-2.1	-1.4	-0.1	0.2
Medication: Levothyroxine sodium	0.9	1.4	3.0	1.5	-1.2	0.7	-1.0	-1.0	-0.1	-1.3	-1.7	-1.4
Sitting height	0.1	0.8	3.3	1.1	-0.5	0.1	-0.1	-0.7	-1.1	-0.4	-0.5	1.8
Chronic bronchitis/emphysema (father)	1.1	1.3	1.9	-1.2	1.2	-1.4	1.3	1.2	0.0	1.3	0.3	1.4
High blood pressure (mother)	0.4	0.5	1.4	-0.7	0.6	-0.3	0.9	0.8	1.2	0.5	0.2	1.0
Body mass index (BMI)	0.7	3.0	4.8	1.8	-2.0	0.7	-1.7	-1.8	-1.6	-2.1	-1.5	-2.2
Impedance of leg (left)	0.7	3.2	10.1	-1.4	1.6	-0.3	1.0	1.4	2.3	1.7	-1.8	3.2
Leg predicted mass (left)	0.4	1.9	3.4	1.5	-1.6	-0.0	-1.0	-1.3	-1.9	-1.8	-0.6	-1.5
Trunk fat mass	0.5	2.1	5.5	1.5	-1.6	1.2	-1.5	-1.4	-1.0	-1.6	-2.3	-0.3
Waist circumference	1.0	3.5	11.0	1.6	-1.8	1.4	-1.4	-1.6	-1.5	-2.0	-3.3	-1.6
Number of incorrect matches in round	0.4	0.7	4.1	0.5	-0.3	2.0	-0.5	-0.2	0.4	-0.5	0.2	-1.1
Past tobacco smoking	0.7	1.3	2.5	1.3	-1.1	0.4	-1.0	-1.2	-1.6	-1.3	-1.3	0.1
Alcohol usually taken with meals	2.3	3.7	7.1	-2.6	2.7	0.5	2.3	2.5	1.0	2.6	0.4	-0.1
Nervous feelings	0.2	0.4	0.8	0.7	-0.9	-0.3	-0.7	-0.9	0.4	-0.6	-0.3	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	2.4	1.4	-1.4	-0.1	-1.4	-1.5	-0.5	-1.3	-0.1	-0.1
Hearing difficulty/problems with background noise	0.7	1.1	3.8	-0.9	0.8	-0.8	1.1	0.9	-1.4	0.7	-0.2	-1.9
Hair/balding pattern: Pattern 2	0.1	0.2	0.7	0.5	-0.2	0.8	-0.4	-0.4	0.1	-0.3	0.2	0.5
Had menopause	0.7	0.9	3.9	0.1	-0.4	0.2	-0.7	-0.4	-0.0	-0.2	1.7	2.0
Had other major operations	0.7	0.9	6.0	0.2	-0.4	2.4	-0.2	-0.3	-0.5	-0.5	-0.4	-1.0
Forced vital capacity (FVC)	0.8	3.1	6.7	-1.4	2.1	-2.6	2.5	1.9	1.0	2.0	0.4	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	1.7	1.3	-1.1	-1.2	-1.0	-1.1	0.4	-1.1	-0.5	-1.0
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	2.8	-0.3	0.9	0.6	0.5	0.5	1.4	1.0	-1.7	0.6
Qualifications: None of the above	0.2	0.5	2.0	-0.3	0.2	1.0	-0.1	0.3	0.1	0.0	-0.9	-1.4
Financial difficulties in last 2 years	1.4	1.8	2.6	1.6	-1.4	1.1	-1.5	-1.5	-1.6	-1.5	-1.2	-0.3
Mouth/teeth dental problems	0.8	1.3	2.2	1.1	-1.2	-0.7	-1.2	-1.4	-1.5	-1.0	0.4	-1.1
Heart attack	1.4	1.8	3.0	1.4	-1.7	1.0	-1.7	-1.7	-1.3	-1.5	-0.4	0.7
Allergy	0.6	1.3	4.1	-1.1	1.2	0.6	1.2	1.2	0.1	1.2	2.0	0.4
Pain all over the body in last month	2.1	2.2	5.3	1.1	-1.3	2.3	-1.3	-1.5	-1.9	-1.3	0.2	-1.6
Diabetes (self-reported)	0.6	0.9	2.8	0.6	-0.7	1.5	-0.9	-0.6	0.9	-0.6	-1.7	-0.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.6	-0.3	0.2	-0.6	0.6	0.2	-1.0	0.2	-0.2	-1.3
Medication: Ramipril	0.7	0.9	2.4	-0.7	0.9	-0.9	0.8	1.0	0.6	1.0	-0.4	-1.5
Medication: Simvastatin	0.3	0.5	1.9	-0.7	0.2	0.2	0.3	0.4	1.4	0.2	1.0	0.7
Fluid intelligence score	0.4	0.8	1.7	-0.7	0.9	-1.2	0.8	0.9	0.8	0.8	1.3	0.1
Illnesses of siblings	0.2	0.3	1.2	0.3	-0.3	-1.1	-0.5	-0.6	-0.1	-0.3	0.4	0.8
Neuroticism score	0.6	1.2	2.2	1.4	-1.3	-0.3	-1.1	-1.2	-0.8	-1.3	-1.5	-0.6
Weight	0.4	1.9	3.1	1.5	-1.6	0.3	-1.1	-1.4	-1.5	-1.8	-1.6	-1.2
Impedance of arm (right)	0.5	2.4	8.6	-1.4	1.3	0.3	0.9	1.1	2.2	1.4	0.4	2.9
Arm fat percentage (right)	0.5	2.1	3.1	1.3	-1.7	1.7	-1.7	-1.5	-0.9	-1.8	-1.3	-0.8
Trunk fat-free mass	0.2	1.0	2.1	1.3	-1.2	-0.1	-0.6	-0.9	-1.4	-1.4	-0.3	-0.8
Hip circumference	0.9	3.9	9.0	2.2	-2.0	0.5	-1.6	-1.8	-1.9	-2.3	-3.0	-1.5
Time employed in main current job	0.4	0.5	1.8	-0.3	0.1	1.2	0.2	0.4	0.7	-0.0	-1.3	-0.4
Alcohol intake versus 10 years previously	0.8	1.2	3.0	-1.7	1.4	1.3	0.8	1.2	-0.3	1.4	-0.2	-0.6
Father’s age at death	1.8	2.4	3.2	-1.8	1.5	-1.4	1.8	1.7	1.7	1.4	1.1	1.3
Worrier / anxious feelings	0.4	0.8	1.5	1.1	-1.2	0.9	-1.2	-1.0	0.1	-1.0	-0.6	0.5
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.4	4.7	1.9	-2.1	0.1	-2.0	-2.2	-1.3	-2.1	-2.1	-1.7
Falls in the last year	0.7	0.9	1.4	-0.9	1.1	-0.4	1.1	1.1	-1.2	1.1	0.6	-0.7
Hair/balding pattern: Pattern 3	0.4	0.6	1.5	-1.2	0.9	0.7	0.8	1.0	0.2	0.8	0.6	-0.2
Number of live births	0.3	0.4	1.1	-0.6	0.6	1.0	0.3	0.3	-0.2	0.5	-0.5	0.9
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	5.8	-0.7	1.1	-2.4	1.6	0.9	-0.4	1.1	0.1	-0.0
Pulse rate	1.1	1.8	3.6	1.2	-1.4	1.9	-1.5	-1.5	0.4	-1.2	-0.9	1.4
Happiness	2.0	2.4	4.6	2.2	-1.8	-0.2	-1.7	-1.9	-0.9	-1.7	-1.8	-0.1
Noisy workplace	2.5	3.0	5.1	-1.9	1.9	-0.4	2.2	2.0	1.6	2.1	-1.9	0.5
Qualifications: A levels/AS levels or equivalent	0.6	1.3	3.0	-0.9	1.2	-0.2	1.4	1.3	0.9	1.3	0.2	1.7
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.5	0.2	-0.4	-0.6	-0.3	-0.3	-0.7	-0.4	-0.7	-0.2
Mouth/teeth dental problems: Dentures	0.6	1.0	4.1	-0.7	0.7	2.0	0.6	1.1	0.7	0.6	0.9	0.4
Asthma	0.7	1.5	3.5	1.7	-1.7	0.4	-1.2	-1.4	0.0	-1.9	0.6	-0.3
Medication: Ibuprofen (e.g. Nurofen)	3.1	3.9	15.5	1.6	-1.6	0.8	-1.4	-1.6	-3.9	-1.5	0.1	-2.7
Medication: Cholesterol lowering	0.2	0.3	1.7	-0.1	-0.4	1.3	-1.0	-0.4	-0.1	-0.3	-0.1	0.1
Depression (self-reported)	0.5	0.6	2.5	-0.1	0.2	1.5	0.3	0.4	0.3	0.1	-0.4	1.6
Medication: Lansoprazole	0.3	0.3	1.3	-0.7	0.2	-0.3	0.2	0.4	0.6	0.1	0.6	1.1
Prospective memory result	0.2	0.2	1.0	-0.1	-0.2	-1.0	0.2	-0.3	-0.2	-0.4	0.7	0.2
Lung cancer (father)	1.4	1.7	6.5	1.1	-1.1	0.3	-1.0	-1.2	-1.0	-1.2	-2.5	-1.2
Illnesses of mother	0.5	0.7	2.1	0.2	0.1	-0.5	-0.2	-0.3	-1.4	0.0	-1.4	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	4.1	-0.6	0.9	-2.0	1.4	0.7	-0.7	0.8	0.3	-0.6
Pulse wave Arterial Stiffness index	2.6	3.0	6.0	2.0	-2.3	0.4	-2.1	-2.3	-0.3	-2.5	0.7	1.2
Impedance of arm (left)	0.5	2.1	5.9	-1.4	1.4	0.1	0.8	1.1	2.3	1.5	-0.1	2.4
Arm fat mass (right)	0.6	2.3	3.7	1.5	-1.8	1.3	-1.6	-1.6	-1.2	-1.9	-1.3	-1.4
Trunk predicted mass	0.2	1.0	1.9	1.3	-1.2	-0.1	-0.6	-0.9	-1.4	-1.4	-0.3	-0.9
Standing height	0.1	1.0	4.3	-0.7	0.8	-1.1	1.2	0.9	0.1	0.7	-0.3	2.1
Length of working week for main job	1.3	1.4	3.8	-1.2	0.7	-2.0	1.3	0.9	0.6	0.8	-1.8	0.4
Exposure to tobacco smoke at home	0.3	0.4	2.0	-0.5	0.1	0.4	0.2	0.1	1.4	-0.0	-0.2	0.9
Breastfed as a baby	0.4	0.5	0.8	-0.2	0.8	0.8	0.7	0.8	0.9	0.9	0.7	-0.1
Tense / ‘highly strung’	0.4	0.7	3.0	0.1	0.1	0.7	0.3	0.0	1.3	0.2	-1.2	1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	3.7	0.5	-0.1	1.9	-0.3	-0.8	-0.2	-0.0	-1.6	-0.3
Hair/balding pattern: Pattern 4	0.2	0.6	1.3	0.4	-0.6	1.0	-0.7	-0.5	-0.4	-0.6	-1.0	-1.2
Birth weight of first child	0.2	0.5	2.0	0.3	-0.1	-1.4	-0.1	0.0	0.6	-0.2	1.3	0.2
Peak expiratory flow (PEF)	0.2	0.5	1.4	-0.4	0.8	-0.2	1.2	0.6	-1.2	0.7	0.5	-0.4
Pulse wave reflection index	0.5	0.6	3.1	0.0	-0.3	-1.8	-0.0	-0.3	0.2	-0.5	-1.0	0.9
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.0	0.5	0.0	1.4	-0.3	-0.3	0.2	0.1	-1.4	1.3
Loud music exposure frequency	1.2	1.3	10.6	-0.1	0.2	-0.0	0.3	0.2	0.9	0.2	-3.3	0.5
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.0	-0.7	0.7	-0.8	0.9	0.9	0.4	0.8	0.9	1.4
Mouth/teeth dental problems: Bleeding gums	1.6	2.1	3.9	-2.0	1.7	-0.1	1.7	1.5	1.9	1.4	-0.0	1.2
Blood clot in the leg (DVT)	1.6	2.1	3.9	1.3	-2.0	0.4	-1.8	-1.9	-1.3	-2.0	-0.7	0.1
Medication: Paracetamol	2.7	4.4	8.0	2.5	-2.6	0.4	-2.5	-2.8	-1.7	-2.6	-1.1	-0.9
Headache pain in last month	0.2	0.3	0.9	0.3	-0.2	-0.3	0.1	-0.3	-0.8	-0.1	-0.7	-1.0
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	4.2	-0.5	0.8	-2.0	1.3	0.8	0.8	0.7	-0.3	1.3
Glaucoma (self-reported)	0.7	0.9	3.2	0.1	-0.6	-1.8	-0.4	-0.4	0.0	-0.6	1.4	-1.3
Gout (self-reported)	1.0	1.3	2.2	-1.5	1.1	-0.1	1.2	1.3	0.6	1.1	1.4	-1.3
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	4.8	0.4	-0.4	-0.9	0.0	-0.4	0.2	-0.5	-2.2	-1.6
Medication: Amlodipine	0.9	1.2	9.8	0.0	-0.1	0.4	-0.7	-0.2	-0.2	-0.2	-3.1	-0.6
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.5	0.7	-1.1	0.8	-1.1	-1.0	-0.2	-1.2	-0.5	-0.3
Birth weight	0.1	0.3	1.6	-0.3	-0.0	-0.0	-0.2	-0.3	-0.7	0.1	1.3	0.2
Chronic bronchitis/emphysema (mother)	1.2	1.4	3.9	1.2	-0.9	1.7	-1.0	-1.0	-1.0	-0.9	2.0	-0.3
High blood pressure (siblings)	0.3	0.5	2.2	-0.3	0.4	0.3	0.5	0.5	0.2	0.5	-1.5	-1.0
Forced vital capacity (FVC), Best measure	0.5	1.6	4.0	-1.0	1.5	-2.0	1.8	1.3	0.1	1.3	0.9	0.1
Body fat percentage	0.6	2.2	6.2	1.3	-1.5	1.5	-1.5	-1.4	-0.6	-1.5	-2.5	-0.3
Leg fat percentage (right)	0.6	2.2	7.8	1.2	-1.4	1.6	-1.4	-1.2	-0.6	-1.5	-2.8	-0.6
Arm fat-free mass (right)	0.5	2.4	4.8	1.8	-1.7	-0.6	-1.1	-1.4	-2.2	-1.9	-1.0	-1.5
Exposure to tobacco smoke outside home	0.1	0.2	0.6	-0.1	0.3	-0.3	0.3	0.2	0.5	0.3	-0.8	-0.4
Comparative body size at age 10	0.6	1.7	6.8	1.0	-1.3	-0.1	-0.5	-0.9	-1.8	-1.0	2.6	-0.7
Number of full brothers	0.3	0.4	1.4	0.6	-0.3	0.9	-0.6	-0.8	-1.2	-0.1	-0.1	-0.5
Worry too long after embarrassment	0.3	0.6	1.6	0.8	-0.7	-0.5	-0.7	-0.6	-0.2	-0.8	-0.8	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	3.8	0.6	-0.7	2.0	-0.7	-0.8	-0.1	-0.7	-0.2	-0.3
Wheeze or whistling in the chest in last year	0.2	0.4	1.8	-0.4	-0.2	0.8	-0.1	0.3	-0.2	-0.4	-1.3	-0.6
Number of children fathered	3.7	4.1	7.1	-2.7	2.2	-2.0	2.5	2.4	1.8	2.2	0.8	0.7
Reason for reducing amount of alcohol drunk: Health precaution	5.6	6.6	12.1	3.4	-3.3	-1.5	-2.9	-3.5	-1.8	-3.3	-0.5	-0.7
Age at first live birth	0.4	0.8	3.5	-0.1	0.2	-1.9	1.1	0.5	1.1	0.2	0.6	0.5
Pulse wave peak to peak time	2.9	3.5	6.9	-2.2	2.5	-0.3	2.3	2.4	0.5	2.6	-0.6	-1.0
Health satisfaction	0.8	1.0	2.1	1.4	-1.3	-0.3	-1.0	-1.3	0.4	-1.2	-1.0	-0.3
Shortness of breath walking on level ground	0.4	0.4	1.4	0.6	-0.3	1.2	-0.8	-0.6	-0.2	-0.1	-1.0	0.3
Qualifications: College or University degree	0.8	2.6	9.6	-0.8	1.1	-1.9	1.7	1.2	1.7	1.1	0.6	3.1
Eye problems/disorders: None of the above	1.8	2.1	5.1	1.4	-1.3	2.3	-1.5	-1.2	-0.6	-1.2	-1.7	0.9
Mouth/teeth dental problems: Loose teeth	1.3	1.5	4.3	-1.0	1.0	-1.5	1.0	1.2	2.1	1.2	-0.7	0.8
Emphysema/chronic bronchitis	0.1	0.1	0.4	-0.2	-0.3	0.6	-0.7	-0.2	-0.5	-0.1	0.0	-0.2
Medication for pain relief, constipation, heartburn	1.9	3.3	4.7	-1.7	2.2	-1.2	2.1	2.1	1.9	2.1	1.2	1.6
Neck or shoulder pain in last month	0.6	0.8	3.5	1.2	-0.6	-0.5	-0.4	-0.6	-0.2	-0.7	1.9	0.6
Medication: Blood pressure	0.8	1.3	3.8	0.6	-0.9	1.9	-1.0	-0.7	-0.8	-0.9	0.3	-2.0
Angina (self-reported)	0.3	0.3	2.0	-0.5	0.2	1.4	-0.1	0.4	0.2	-0.1	-0.8	0.3
Migraine (self-reported)	0.9	1.1	5.8	0.4	-0.5	2.4	-0.5	-0.6	-1.7	-0.5	-0.0	0.6
Medication: Ibuprofen	1.7	2.0	6.7	1.3	-1.2	-0.3	-0.9	-1.2	-2.6	-1.2	0.1	-2.1
Medication: Allopurinol	2.2	3.0	4.9	-2.0	2.0	0.6	2.1	2.2	1.8	1.8	1.2	-0.9
Medication: Omeprazole	0.2	0.3	1.2	-0.3	-0.1	0.2	0.2	-0.0	-1.1	-0.1	0.9	0.6
Medication: Seretide 50 evohaler	0.6	0.7	1.4	0.9	-1.1	0.2	-1.1	-0.9	-0.1	-1.2	-0.2	0.7
Mean time to correctly identify matches	0.3	0.7	3.9	-0.8	0.8	2.0	0.2	0.4	-0.2	0.6	0.2	0.2
Heart disease (mother)	0.4	0.5	2.4	-0.1	0.0	0.2	0.5	0.3	1.5	-0.2	0.9	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.0	0.5	-0.1	0.4	-0.7	-0.4	-1.0	-0.1	-0.3	0.5
Whole body fat mass	0.5	2.0	4.8	1.3	-1.5	1.0	-1.3	-1.4	-0.9	-1.7	-2.2	-0.7
Leg fat mass (right)	0.6	2.4	5.3	1.4	-1.8	0.8	-1.5	-1.5	-1.3	-1.9	-2.3	-1.1
Arm predicted mass (right)	0.5	2.4	4.6	1.9	-1.8	-0.4	-1.3	-1.5	-2.2	-1.9	-0.9	-1.4
Pulse rate, automated reading	1.3	4.1	6.0	2.3	-2.2	2.5	-2.2	-2.0	0.8	-2.0	-1.6	2.1
Alcohol intake frequency.	0.7	1.7	4.8	0.5	-0.7	1.0	-1.0	-1.1	-2.0	-0.8	-2.2	-1.4
Comparative height size at age 10	0.1	0.4	1.3	-0.3	0.1	1.1	0.7	0.6	0.1	0.1	1.0	-0.5
Number of full sisters	1.3	1.6	7.6	0.2	0.0	-1.7	0.0	-0.5	-0.0	0.0	-1.8	-2.8
Suffer from ‘nerves’	0.6	0.9	1.9	1.1	-1.0	1.1	-0.7	-0.9	0.4	-0.9	-1.4	0.6
Overall health rating	3.1	6.6	15.1	2.8	-2.6	1.3	-2.6	-2.8	-2.1	-2.5	-3.9	-1.7
Chest pain or discomfort	0.1	0.2	0.4	-0.2	0.4	0.0	0.3	0.7	-0.4	0.4	-0.5	-0.3
Had major operations	0.4	0.4	2.2	-0.3	0.4	1.5	0.5	0.4	-0.7	0.3	-0.1	-0.6
Age at last live birth	0.0	0.1	0.2	-0.1	0.2	0.1	0.5	0.2	-0.1	0.2	-0.2	0.4
Family relationship satisfaction	2.4	2.9	5.4	1.7	-1.9	-0.3	-2.3	-2.0	-1.2	-1.9	-2.0	-0.9
Leg pain on walking	0.2	0.2	0.7	0.4	-0.3	-0.5	-0.4	-0.3	-0.1	-0.1	0.7	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.5	0.3	-0.1	1.1	-0.6	-0.4	0.5	-0.2	-1.2	-1.1
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.7	-0.6	0.7	-0.6	0.8	0.7	0.6	0.6	-1.6	1.1
Illness, injury, bereavement, stress in last 2 years	1.3	1.5	5.8	-0.7	0.8	-0.6	0.8	0.9	2.4	0.9	1.8	0.9
Medication: Aspirin	0.3	0.4	1.5	-0.3	0.0	-0.4	0.1	0.3	1.2	0.2	-0.7	1.2
Supplements: Vitamin C	3.3	3.9	7.2	-2.2	2.5	1.2	2.4	2.7	1.6	2.3	0.8	-1.0
Knee pain experienced in last month	0.4	0.7	1.3	-0.9	0.8	-0.7	1.1	0.9	0.4	0.7	-0.6	-0.9
Hypertension (Self-reported)	0.4	1.2	4.6	0.1	-0.5	2.2	-1.0	-0.5	-0.5	-0.5	-1.6	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.0	-0.7	0.8	-0.8	0.7	0.5	0.0	0.7	-1.2	1.4
Illnesses of father: Heart disease	0.1	0.1	0.8	0.1	0.3	0.0	0.0	0.2	0.0	0.4	0.9	0.5
Illnesses of siblings: Diabetes	0.3	0.4	1.1	-0.5	0.6	-0.1	1.0	0.7	-0.7	0.6	0.2	-0.3
Smoking status: Previous	0.7	1.1	3.5	-1.0	1.0	-0.6	1.2	1.1	1.9	1.1	0.6	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.6	0.4	0.1	-0.8	0.4	0.2	0.2	-0.1	-0.6	0.3
Whole body fat-free mass	0.3	1.7	3.2	1.6	-1.5	-0.1	-0.9	-1.2	-1.8	-1.7	-0.5	-1.3
Leg fat-free mass (right)	0.3	1.4	2.7	1.4	-1.4	-0.2	-0.7	-1.2	-1.6	-1.5	-0.2	-1.4
Arm fat percentage (left)	0.5	2.1	2.8	1.3	-1.6	1.5	-1.7	-1.5	-0.7	-1.7	-1.7	-0.9
Average weekly red wine intake	1.4	2.1	3.9	-1.9	1.8	-0.1	2.0	1.6	1.3	1.8	-0.1	0.7
Handedness (chirality/laterality): Left-handed	1.8	2.2	4.8	-1.7	1.7	-1.2	2.2	1.6	-1.3	1.6	-0.9	-0.3
Mood swings	0.3	0.6	1.3	1.1	-1.0	-0.3	-0.7	-0.9	-0.6	-1.1	-0.5	0.1
Loneliness, isolation	5.3	7.3	12.7	3.6	-3.3	-0.0	-2.9	-3.0	-2.3	-3.2	-2.3	-1.9
Long-standing illness, disability or infirmity	2.6	4.0	9.2	2.3	-2.2	3.0	-1.9	-1.9	-0.8	-2.4	-1.5	-1.1
Ever had bowel cancer screening	0.1	0.2	0.7	0.3	-0.3	-0.6	-0.1	-0.1	0.4	-0.2	-0.9	-0.1
Diabetes diagnosed by doctor	0.4	0.7	3.0	0.1	-0.1	1.7	-0.5	-0.1	0.7	-0.0	-1.5	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.0	0.8	-0.7	0.9	-0.8	-0.8	-0.2	-0.7	-0.1	1.4
Friendships satisfaction	4.3	5.4	9.4	2.8	-2.7	1.6	-2.8	-3.1	-2.2	-2.8	-0.2	-0.3
Qualifications: nursing, teaching	1.1	1.8	6.1	-0.8	0.8	-2.5	1.1	0.8	1.3	1.0	1.0	1.8
Commuting to job workplace: Walk	0.3	0.3	1.5	0.4	0.0	-0.1	-0.1	-0.1	-1.2	0.2	-0.1	-1.2
Eye problems/disorders: Cataract	1.3	1.5	3.5	-1.3	1.3	-1.9	1.6	1.2	1.0	1.2	-0.0	0.2
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.0	1.4	-1.3	-0.6	-1.3	-1.2	0.2	-1.3	-1.0	0.3
Medication for cholesterol	0.4	0.6	2.4	-0.1	0.3	-0.4	0.1	0.0	-1.2	0.4	1.5	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.3	-0.1	-0.1	1.1	-0.4	0.0	-0.6	-0.0	0.2	-1.1
Back pain experienced in last month	0.5	0.7	1.6	1.3	-1.1	-0.9	-0.6	-0.9	-0.5	-1.0	-0.4	0.7
Mineral and other dietary supplements	0.1	0.1	0.4	-0.2	-0.0	0.5	-0.1	0.1	0.7	-0.0	0.4	0.4
Breast cancer (self-reported)	1.0	1.2	2.0	1.4	-1.0	1.0	-1.4	-1.2	0.6	-1.0	1.1	0.6
Asthma (self-reported)	0.6	1.2	3.0	1.5	-1.5	-0.1	-1.0	-1.3	0.3	-1.7	0.7	-0.1
Osteoporosis (self-reported)	0.4	0.5	1.6	1.0	-0.5	0.9	-0.8	-0.4	-0.2	-0.5	-0.5	1.3
Osteoarthritis (self-reported)	0.4	0.5	1.0	-0.7	0.8	0.2	1.0	0.7	0.1	0.8	-0.9	-0.8
Medication: Aspirin	0.4	0.5	1.6	0.1	-0.3	-0.0	-0.4	-0.1	1.2	-0.1	-1.0	1.2
Medication: Gliclazide	0.3	0.4	2.0	0.4	0.0	-1.4	0.4	0.3	0.9	-0.2	-0.5	-0.2
Illnesses of father: None of the above (group 1)	0.7	0.8	1.4	0.6	-1.2	0.0	-0.9	-0.9	-1.2	-1.2	-1.0	-0.4
Smoking status: Current	0.2	0.3	0.9	0.3	-0.5	0.2	-0.8	-0.2	-1.0	-0.4	-0.1	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	3.6	-0.4	1.0	-0.8	1.0	0.7	-0.1	0.8	1.9	-0.3
Whole body water mass	0.3	2.0	3.8	1.7	-1.6	0.0	-1.0	-1.4	-2.0	-1.9	-0.5	-1.3
Leg predicted mass (right)	0.3	1.5	2.8	1.4	-1.4	-0.2	-0.8	-1.2	-1.7	-1.6	-0.3	-1.4
Arm fat mass (left)	0.5	1.9	3.3	1.3	-1.7	0.9	-1.4	-1.4	-1.1	-1.8	-1.3	-1.2
Number of self-reported non-cancer illnesses	2.0	3.4	7.8	1.5	-1.9	2.8	-2.2	-1.9	-1.4	-1.9	-1.5	-0.9
Average weekly champagne plus white wine intake	0.8	1.1	2.8	-0.3	0.9	-1.3	1.2	0.9	1.7	0.7	-1.3	0.4
Miserableness	1.7	3.0	4.3	1.8	-1.9	-0.1	-1.8	-2.1	-2.1	-1.7	-1.2	-1.9
Guilty feelings	0.6	0.8	2.0	-0.8	1.0	-0.3	1.4	1.1	0.3	1.0	-1.0	0.8
Wears glasses or contact lenses	1.3	1.5	4.0	-1.1	1.1	0.8	1.2	1.3	1.3	1.0	2.0	-0.2
Ever taken oral contraceptive pill	0.4	0.5	1.3	0.0	-0.2	0.9	-0.7	-0.4	-1.1	-0.1	1.1	-0.6
Hearing aid user	0.9	1.0	2.4	-1.6	1.1	-1.3	1.4	1.1	0.4	0.7	-0.5	0.3
Mother’s age at death	0.3	0.3	1.8	-0.4	0.1	1.3	0.3	0.2	-0.4	0.1	0.8	0.1
Financial situation satisfaction	1.8	2.2	4.0	-1.6	1.9	-1.3	1.7	1.6	0.4	2.0	-1.2	-0.8
Tinnitus: Yes, now most or all of the time	1.5	1.8	4.5	-1.4	1.2	-0.8	1.7	1.5	0.9	1.1	-2.1	0.7
Commuting to job workplace: Public transport	0.4	0.5	1.9	0.3	-0.3	0.6	-0.9	-0.4	-0.5	-0.2	1.4	-1.1
Eye problems/disorders: Glaucoma	1.0	1.2	6.0	-0.4	0.3	-2.4	0.5	0.4	0.2	0.4	1.6	-1.3
Medication: Blood pressure	0.5	0.9	5.1	0.3	-0.4	1.1	-0.5	-0.3	-0.2	-0.4	-2.3	0.8
Pain type(s) experienced in last month: Hip pain	3.9	4.9	11.3	3.4	-2.7	-0.8	-2.5	-2.6	-2.1	-2.4	0.4	-1.1
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.1	0.3	0.1	-0.0	-0.1	-0.1	-0.3	-0.0	0.1	-0.1
High cholesterol (Self-reported)	0.2	0.3	0.6	-0.8	-0.0	0.4	-0.1	0.1	0.7	-0.0	-0.8	-0.7
Medication: Bendroflumethiazide	0.9	1.3	2.3	-1.4	1.4	0.1	1.4	1.5	1.2	1.5	-0.1	-0.3
Medication: Paracetamol	4.4	6.8	12.4	3.4	-3.4	0.3	-3.2	-3.5	-1.5	-3.4	-1.1	-0.7
Medication: Lisinopril	0.3	0.3	0.8	-0.7	0.6	0.3	0.7	0.9	0.6	0.5	0.2	-0.4
Medication: Atorvastatin	0.7	0.8	1.7	0.9	-1.3	0.6	-1.3	-0.9	-0.4	-1.2	-0.3	-0.6
Illnesses of father: High blood pressure	0.2	0.3	1.2	0.2	0.2	-0.1	0.3	0.1	1.1	0.2	-1.0	-0.4
Alcohol drinker status: Never	2.9	3.5	7.0	2.1	-2.3	1.2	-2.6	-2.4	-1.7	-2.1	-0.1	-0.4
Ever smoked	1.2	2.2	5.0	-2.2	1.8	-0.1	1.2	1.8	0.3	2.0	1.3	-0.9
Basal metabolic rate	0.3	1.9	3.5	1.6	-1.6	0.1	-1.0	-1.3	-1.9	-1.8	-0.8	-1.3
Leg fat percentage (left)	0.6	2.1	7.5	1.2	-1.3	1.5	-1.3	-1.2	-0.5	-1.4	-2.7	-0.6
Arm fat-free mass (left)	0.4	2.1	4.0	1.8	-1.8	-0.1	-1.1	-1.4	-2.0	-1.9	-0.8	-1.2
Number of operations (self-reported)	0.3	0.4	1.8	-0.4	0.3	1.4	0.5	0.3	-0.5	0.3	-0.1	-1.1
Average weekly beer plus cider intake	1.8	2.5	5.0	-1.6	1.8	-1.0	1.8	1.4	1.2	2.0	0.6	2.2
Irritability	0.5	0.8	2.0	1.4	-1.0	-0.1	-1.2	-0.9	0.1	-1.0	0.8	0.3
Risk taking	1.1	1.5	4.5	-0.7	0.8	-2.1	1.2	0.9	1.8	1.0	0.5	1.1
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.1	-0.1	-0.0	1.0	-0.4	-0.4	-1.0	-0.0	-0.1	-0.7
Fractured/broken bones in last 5 years	1.3	1.7	4.5	-2.1	1.5	0.7	1.2	1.5	-0.6	1.8	0.6	-0.4
Age started oral contraceptive pill	3.7	4.6	17.8	-1.8	1.9	-0.9	2.1	2.0	1.7	2.1	4.2	0.4
Diastolic blood pressure, automated reading	0.2	0.5	2.0	0.2	-0.4	1.1	-0.6	-0.3	-0.1	-0.3	-0.9	-1.4
Ever depressed for a whole week	0.3	0.4	1.5	0.0	0.2	0.5	0.4	0.0	-0.3	0.1	-1.2	-1.1
Unable to work because of sickness or disability	1.0	1.3	2.0	1.1	-0.9	1.4	-1.3	-1.0	-1.4	-0.8	-1.1	-1.0
Commuting to job workplace: Cycle	0.6	0.8	3.2	-0.0	0.2	-1.1	0.5	0.1	-1.1	0.2	-1.8	-1.1
Myopia	0.7	1.0	2.2	0.9	-1.2	-0.6	-1.1	-1.5	-0.1	-1.1	1.0	0.9
Vascular/heart problems diagnosed by doctor	0.7	1.9	5.5	-0.6	1.2	-2.3	1.6	1.1	1.3	1.1	1.0	1.4
Cholesterol lowering medication	0.7	1.0	5.0	-1.0	0.5	0.1	1.1	1.0	2.2	0.5	-0.8	0.1
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.4	0.1	-0.5	-0.5	0.1	-0.3	-0.3	-0.6	0.2	-0.2
Pain experienced in last month	0.5	0.9	2.6	-1.0	0.8	0.1	0.3	0.7	1.2	0.8	-0.9	1.6
Supplements: Calcium	0.8	0.9	3.4	0.8	-0.9	1.9	-0.8	-0.8	-0.4	-1.1	-0.4	0.6
Basal cell carcinoma (self-reported)	0.9	1.1	2.2	0.9	-1.4	-0.5	-1.2	-1.3	-1.1	-1.5	-0.4	-0.5
Heart attack/myocardial infarction (self-reported)	1.1	1.4	2.5	1.1	-1.5	0.7	-1.6	-1.5	-1.2	-1.4	-0.3	0.7
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	3.4	1.2	-1.8	0.3	-1.7	-1.8	-0.8	-1.8	-0.8	0.6
Heart disease (siblings)	0.6	0.7	1.6	0.8	-1.1	1.3	-0.7	-0.7	-0.4	-1.1	0.7	0.2
Alcohol drinker status: Previous	0.3	0.3	1.2	-0.2	-0.0	1.0	0.1	-0.1	-0.5	-0.0	0.5	-1.1
Pack years of smoking	0.3	0.5	1.9	-0.1	-0.1	0.4	-0.3	0.3	-0.4	-0.0	-1.3	1.4
Impedance of whole body	0.7	3.5	10.6	-1.7	1.9	-0.3	1.2	1.5	2.3	2.0	-0.8	3.3
Leg fat mass (left)	0.6	2.2	5.7	1.4	-1.6	0.8	-1.3	-1.4	-1.2	-1.7	-2.4	-1.0
Arm predicted mass (left)	0.4	1.8	4.1	1.6	-1.5	-0.1	-0.9	-1.2	-2.0	-1.7	-0.7	-1.3