Hub : Genes

KIAA1967

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 NTR Blood 0.0336 0.0099 1.7e-05 0.026 0.021 0.034 0.030 0.033 5.1e-09 1.2e-07 4.3e-11 3.4e-10 6.8e-11
2 YFS Blood 0.0511 0.0137 1.8e-09 0.038 0.035 0.031 0.037 0.036 2.1e-12 9.6e-12 1.8e-10 2.5e-12 4.8e-12

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 3.4 5.4 10.0 -0.9 3.2
Bipolar Disorder or Schizophrenia 1.0 2.3 3.8 -0.9 2.0
Depressed Affect (Nagel 2018) 3.5 7.4 10.8 2.0 -3.3
Depression (Nagel 2018) 1.6 2.4 4.2 0.8 -2.0
Intelligence (Savage-Jansen 2018) 0.2 0.7 1.3 -1.2 -0.3
Neuroticism (Nagel 2018) 1.0 2.3 4.4 0.4 -2.1
Schizophrenia (2018) 0.0 0.1 0.2 -0.4 -0.1
Schizophrenia vs Biploar Disorder 0.8 1.1 1.9 0.5 -1.4
Worry (Nagel 2018) 0.1 0.3 0.6 -0.8 0.1
Alzheimer’s Disease (in mother) 0.8 1.0 1.9 1.4 0.1
Alzheimer’s Disease (in father) 2.2 2.4 2.5 -1.6 1.5
Alzheimer’s Disease (including proxy) 0.1 0.2 0.4 0.1 0.6
Crohns Disease (2017) 0.2 0.5 0.9 -0.9 0.3
Irritable Bowel Disease (IBD) 0.2 0.4 0.6 -0.8 -0.3
Ulcerative Colitis (UC) 0.0 0.0 0.1 -0.0 -0.2
Major Depression (MDD) 0.5 0.6 1.1 -1.1 0.4
Reaction Time 0.1 0.2 0.4 -0.0 -0.7
Verbal and Numeric Reasoning (VNR) 0.4 1.0 2.0 -1.4 -0.1
Breast Cancer 2.4 5.9 11.7 -3.4 0.1
Ovarian Cancer 0.4 0.5 1.0 1.0 0.3
Prostate Cancer 0.5 0.7 1.1 1.1 -0.5
Age at First Birth 1.2 1.8 3.1 -1.7 0.7
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.4 0.5 0.9 0.3 0.9
Coronary Artery Disease (CAD) 0.6 0.8 1.0 -1.0 0.8
Crohns Disease (2012) 0.5 0.8 1.4 -1.2 0.5
Mean Putamen Volume 0.2 0.2 0.4 -0.1 -0.7
Fasting Glucose 0.2 0.2 0.2 0.5 -0.4
HbA1C 0.6 0.7 1.3 0.1 1.1
HDL Cholesterol 0.1 0.1 0.3 -0.5 -0.0
LDL Cholesterol 1.6 2.5 5.0 2.2 0.3
Lupus 0.1 0.1 0.2 -0.2 0.4
Neuroticism (2016) 0.4 0.6 0.9 -1.0 -0.5
Primary Biliary Cirrhosis 0.2 0.3 0.4 0.5 -0.7
Rheumatoid Arthritis 0.1 0.2 0.3 -0.2 -0.6
Schizophrenia (2014) 0.0 0.1 0.1 0.1 -0.3
Triglycerides 1.1 1.8 3.4 -0.3 1.8
Type 2 Diabetes (T2D) (2012) 1.1 1.2 2.5 -1.6 -0.2
Ulcerative Colitis 0.3 0.4 0.6 0.8 -0.3
Blood Eosinophil Count 0.2 1.6 1.7 -1.3 1.2
Blood Platelet Count 2.7 31.0 40.4 -4.7 6.4
Blood Red Count 1.3 12.6 17.7 4.2 -2.8
Blood White Count 0.7 5.5 10.4 0.7 3.2
Heel T-Score 0.3 2.5 2.7 -1.6 1.5
BMI 0.1 0.6 0.6 0.8 -0.7
Height 0.8 14.7 18.6 3.3 -4.3
Waist Hip Ratio (WHR) 0.3 1.4 2.7 0.4 1.6
Systolic Blood Pressure 0.8 4.2 6.6 1.3 2.6
Smoking Status 2.5 5.9 6.8 2.6 -2.2
Allergy or Eczema 0.4 1.2 1.5 -1.2 0.9
Cardiovascular Disease 0.5 1.5 3.0 0.3 1.7
Hypothyroidism (self reported) 0.2 0.6 0.7 0.7 -0.8
Respiratory disease 0.5 1.0 2.0 -0.2 -1.4
Type 2 Diabetes (T2D) (2018) 4.3 8.0 9.1 -2.6 3.0
Lung FEV1/FVC ratio 3.0 15.1 26.8 -1.8 5.2
Lung FVC 3.0 15.2 16.7 4.1 -3.7
Neuroticism 1.6 3.9 6.7 1.0 -2.6
Chronotype (morning person) 0.3 0.6 0.8 0.7 -0.9
Hair Pigment 0.0 0.6 0.9 -0.6 -0.9
Tanning 0.1 0.8 1.4 -0.3 1.2
Hand grip strength (left) 0.0 0.1 0.1 0.4 -0.1
Number of treatments/medications taken 1.5 2.7 4.6 -0.9 2.1
Average weekly spirits intake 0.2 0.3 0.3 -0.5 0.5
Sensitivity / hurt feelings 0.8 1.4 1.6 -1.1 1.3
Frequency of depressed mood in last 2 weeks 2.1 3.0 4.9 1.0 -2.2
Hearing difficulty/problems: Yes 0.3 0.4 0.7 0.4 -0.8
Relative age of first facial hair 0.1 0.2 0.3 -0.5 0.4
Other serious medical condition/disability diagnosed by doctor 0.6 0.7 1.4 0.2 -1.2
Ever used hormone-replacement therapy (HRT) 0.2 0.2 0.3 -0.6 -0.4
Ever had hysterectomy (womb removed) 0.8 0.8 0.9 -1.0 0.9
Systolic blood pressure, automated reading 0.2 0.6 1.2 -0.0 1.1
Eye problems/disorders: Diabetes related eye disease 2.7 2.9 5.3 -0.8 2.3
Angina 1.3 1.7 3.4 0.1 1.9
Medication for hormone replacement therapy 0.1 0.1 0.2 -0.1 0.4
Vitamin and mineral supplements 1.0 1.4 2.7 1.7 -0.2
Supplements: Zinc 0.5 0.5 0.9 1.0 0.2
Medication: Co-codamol 1.6 1.8 3.6 0.3 1.9
Medication: Metformin 4.3 6.1 6.8 -2.6 2.3
Diabetes (father) 0.7 0.8 0.9 0.9 0.9
Diabetes (mother) 2.3 3.0 4.5 -1.2 2.1
Severe depression (siblings) 0.1 0.1 0.2 0.1 0.4
Pack years adult smoking proportion 0.4 0.6 0.9 -0.9 0.5
Impedance of leg (right) 0.6 2.7 4.0 -1.2 2.0
Leg fat-free mass (left) 0.9 4.6 6.3 1.7 -2.5
Trunk fat percentage 0.0 0.1 0.1 0.3 -0.1
Hand grip strength (right) 0.3 0.9 1.0 0.9 -1.0
Townsend deprivation index at recruitment 0.4 0.5 0.9 -0.5 -0.9
Current tobacco smoking 2.0 3.3 6.7 2.6 0.1
Average weekly fortified wine intake 0.5 0.6 0.9 -0.9 -0.5
Maternal smoking around birth 0.8 1.1 1.8 -1.4 0.6
Fed-up feelings 2.2 4.0 6.8 1.1 -2.6
Frequency of unenthusiasm / disinterest in last 2 weeks 2.7 3.7 6.5 0.9 -2.5
Relative age voice broke 0.3 0.4 0.8 -0.3 0.9
Taking other prescription medications 0.3 0.4 0.8 -0.9 0.2
Age when periods started (menarche) 0.4 0.9 1.3 -0.6 -1.2
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 0.9 1.0 0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.7 1.8 -1.3 1.3
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.3 0.5 -0.2
Qualifications: CSEs or equivalent 0.6 0.7 1.3 -1.1 -0.4
Serious illness, injury or assault to yourself 0.6 0.7 1.2 0.4 -1.1
High blood pressure 0.4 1.0 2.1 0.1 1.4
Hayfever, allergic rhinitis or eczema 1.5 3.2 4.8 -2.2 1.2
Multivitamins +/- minerals 2.7 3.5 6.9 -2.6 0.3
Stomach or abdominal pain in last month 1.1 1.4 2.7 -0.2 -1.7
Supplements: Glucosamine 1.0 1.3 2.7 0.1 -1.6
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 0.7 -0.9 0.5
Medication: Atenolol 0.2 0.3 0.5 0.7 -0.0
Medication: Levothyroxine sodium 0.5 0.9 1.1 0.9 -1.0
Sitting height 0.4 2.9 4.8 1.0 -2.2
Chronic bronchitis/emphysema (father) 0.5 0.6 1.1 -1.1 0.3
High blood pressure (mother) 0.4 0.6 1.1 1.1 0.2
Body mass index (BMI) 0.0 0.1 0.2 0.4 -0.1
Impedance of leg (left) 0.5 2.6 3.5 -1.3 1.9
Leg predicted mass (left) 0.9 4.7 6.4 1.7 -2.5
Trunk fat mass 0.1 0.5 0.9 0.5 -0.9
Waist circumference 0.0 0.1 0.2 0.3 -0.4
Number of incorrect matches in round 0.7 1.2 1.9 -0.7 1.4
Past tobacco smoking 0.9 1.6 1.9 -1.2 1.4
Alcohol usually taken with meals 0.3 0.5 0.7 0.9 -0.6
Nervous feelings 0.1 0.3 0.5 -0.7 0.2
Frequency of tenseness / restlessness in last 2 weeks 2.2 3.4 6.6 -0.5 -2.6
Hearing difficulty/problems with background noise 1.9 3.0 3.2 1.8 -1.7
Hair/balding pattern: Pattern 2 2.2 2.8 5.5 0.2 -2.3
Had menopause 0.4 0.5 0.5 -0.7 0.7
Had other major operations 0.5 0.6 1.0 -0.5 1.0
Forced vital capacity (FVC) 1.7 6.5 7.5 2.3 -2.7
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 1.8 -1.3 0.7
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 0.6 0.8 -0.8
Qualifications: None of the above 0.8 1.6 2.8 1.7 -0.7
Financial difficulties in last 2 years 1.7 2.3 4.5 -2.1 -0.2
Mouth/teeth dental problems 0.2 0.3 0.3 0.4 -0.6
Heart attack 0.8 1.0 1.1 -1.0 -1.0
Allergy 1.5 3.4 6.4 2.5 -0.7
Pain all over the body in last month 0.2 0.2 0.3 -0.3 -0.5
Diabetes (self-reported) 3.1 4.7 7.7 -1.3 2.8
Hayfever/allergic rhinitis (self-reported) 0.8 1.1 1.1 -1.1 -1.0
Medication: Ramipril 1.7 2.1 4.2 -0.3 2.0
Medication: Simvastatin 4.7 6.9 9.0 -2.2 3.0
Fluid intelligence score 0.1 0.2 0.2 -0.4 -0.5
Illnesses of siblings 0.3 0.4 0.5 0.7 -0.6
Neuroticism score 1.1 2.4 4.2 0.8 -2.0
Weight 0.5 2.3 3.1 1.3 -1.8
Impedance of arm (right) 0.1 0.3 0.3 -0.6 0.5
Arm fat percentage (right) 0.0 0.1 0.2 -0.4 0.3
Trunk fat-free mass 0.8 4.4 7.2 1.3 -2.7
Hip circumference 0.3 1.3 2.7 0.1 -1.6
Time employed in main current job 0.4 0.4 0.8 0.9 0.1
Alcohol intake versus 10 years previously 0.1 0.2 0.3 -0.2 0.6
Father’s age at death 0.3 0.4 0.8 0.9 0.3
Worrier / anxious feelings 0.3 0.5 0.8 -0.6 0.9
Frequency of tiredness / lethargy in last 2 weeks 2.0 3.3 6.5 0.2 -2.5
Falls in the last year 0.3 0.4 0.7 -0.8 0.3
Hair/balding pattern: Pattern 3 0.5 0.7 1.1 0.5 1.1
Number of live births 1.2 1.7 3.5 -0.1 1.9
Forced expiratory volume in 1-second (FEV1) 0.5 1.8 2.8 1.7 -0.9
Pulse rate 0.3 0.4 0.5 0.6 0.7
Happiness 3.0 3.6 6.8 0.7 -2.6
Noisy workplace 1.4 1.7 2.5 0.9 1.6
Qualifications: A levels/AS levels or equivalent 0.1 0.1 0.3 -0.5 -0.1
Serious illness, injury or assault of a close relative in last 2 years 1.5 1.7 3.4 -1.8 -0.1
Mouth/teeth dental problems: Dentures 0.4 0.6 0.9 0.6 -1.0
Asthma 1.0 2.0 4.0 -2.0 -0.2
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.1 2.0 0.4 -1.4
Medication: Cholesterol lowering 1.5 2.3 3.3 -1.2 1.8
Depression (self-reported) 0.5 0.6 1.1 -1.1 -0.3
Medication: Lansoprazole 0.8 0.9 1.8 -1.3 -0.3
Prospective memory result 1.1 1.4 2.4 0.6 1.6
Lung cancer (father) 0.3 0.3 0.5 0.3 -0.7
Illnesses of mother 1.0 1.3 2.5 -1.6 0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.6 3.0 1.7 -0.3
Pulse wave Arterial Stiffness index 0.4 0.5 0.7 0.6 -0.8
Impedance of arm (left) 0.0 0.2 0.3 -0.0 0.6
Arm fat mass (right) 0.1 0.4 0.8 0.2 -0.9
Trunk predicted mass 0.8 4.4 7.1 1.3 -2.7
Standing height 0.8 8.2 12.9 1.9 -3.6
Length of working week for main job 0.6 0.7 0.7 0.8 0.9
Exposure to tobacco smoke at home 0.6 0.7 1.2 -0.4 1.1
Breastfed as a baby 0.7 0.9 1.8 -0.2 -1.3
Tense / ‘highly strung’ 0.8 1.4 2.7 -1.6 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 0.5 -0.7 -0.7
Hair/balding pattern: Pattern 4 0.1 0.3 0.5 -0.3 -0.7
Birth weight of first child 0.1 0.2 0.3 -0.6 0.0
Peak expiratory flow (PEF) 0.5 1.1 1.4 1.2 0.9
Pulse wave reflection index 0.4 0.4 0.6 -0.7 -0.6
Ever highly irritable/argumentative for 2 days 2.9 3.5 5.0 2.2 -1.4
Loud music exposure frequency 0.1 0.1 0.2 0.4 -0.0
Qualifications: O levels/GCSEs or equivalent 0.8 1.2 2.1 0.6 -1.4
Mouth/teeth dental problems: Bleeding gums 2.3 3.0 4.2 -1.4 2.0
Blood clot in the leg (DVT) 0.1 0.2 0.3 -0.0 0.6
Medication: Paracetamol 0.2 0.4 0.5 -0.7 0.5
Headache pain in last month 0.3 0.5 0.7 0.5 0.9
Medication for cholesterol, blood pressure or diabetes 2.0 3.3 5.3 1.2 -2.3
Glaucoma (self-reported) 0.4 0.4 0.8 0.9 0.2
Gout (self-reported) 0.5 0.7 0.7 0.8 0.8
Hypothyroidism/myxoedema (self-reported) 0.5 0.9 1.0 1.0 -0.9
Medication: Amlodipine 0.6 0.8 1.7 -0.1 1.3
Medication: Ventolin 100micrograms inhaler 2.1 2.7 5.2 -2.3 0.4
Birth weight 1.3 2.9 5.7 -0.2 2.4
Chronic bronchitis/emphysema (mother) 0.4 0.4 0.6 -0.8 -0.6
High blood pressure (siblings) 0.2 0.2 0.4 0.2 -0.6
Forced vital capacity (FVC), Best measure 1.3 4.8 5.7 2.4 -2.0
Body fat percentage 0.0 0.0 0.0 -0.1 0.1
Leg fat percentage (right) 0.0 0.0 0.1 -0.2 0.3
Arm fat-free mass (right) 0.8 3.9 5.6 1.5 -2.4
Exposure to tobacco smoke outside home 1.2 1.6 2.8 -1.7 0.6
Comparative body size at age 10 0.6 1.6 2.1 1.4 1.1
Number of full brothers 0.3 0.4 0.7 -0.8 0.4
Worry too long after embarrassment 0.8 1.4 2.7 -0.3 -1.6
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 1.9 3.8 -1.9 0.1
Wheeze or whistling in the chest in last year 2.1 3.8 7.4 -2.7 -0.3
Number of children fathered 1.2 1.3 2.2 -0.7 1.5
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 0.3 0.2 -0.6
Age at first live birth 0.0 0.0 0.0 -0.2 -0.1
Pulse wave peak to peak time 0.2 0.3 0.4 -0.6 0.5
Health satisfaction 0.6 0.8 1.1 1.1 -0.7
Shortness of breath walking on level ground 0.8 1.0 1.5 1.2 -0.7
Qualifications: College or University degree 0.0 0.1 0.1 0.3 -0.1
Eye problems/disorders: None of the above 2.1 2.4 3.0 -1.4 1.7
Mouth/teeth dental problems: Loose teeth 0.1 0.1 0.1 0.2 0.3
Emphysema/chronic bronchitis 0.4 0.5 0.6 -0.6 -0.8
Medication for pain relief, constipation, heartburn 0.2 0.3 0.7 0.8 0.0
Neck or shoulder pain in last month 0.6 0.9 1.8 -1.4 0.0
Medication: Blood pressure 1.9 3.4 6.3 -0.7 2.5
Angina (self-reported) 1.2 1.6 3.3 -0.1 1.8
Migraine (self-reported) 0.8 1.0 2.0 0.0 1.4
Medication: Ibuprofen 0.4 0.5 1.0 -0.3 -1.0
Medication: Allopurinol 0.4 0.6 1.2 0.1 1.1
Medication: Omeprazole 0.2 0.3 0.6 0.8 0.1
Medication: Seretide 50 evohaler 1.6 1.9 3.0 -1.7 0.8
Mean time to correctly identify matches 0.2 0.3 0.6 -0.3 -0.7
Heart disease (mother) 0.0 0.0 0.0 -0.0 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 0.3 -0.0 -0.5
Whole body fat mass 0.2 0.7 0.9 0.6 -0.9
Leg fat mass (right) 0.1 0.4 0.7 0.3 -0.9
Arm predicted mass (right) 0.8 4.3 5.8 1.7 -2.4
Pulse rate, automated reading 1.1 3.5 6.9 -0.2 2.6
Alcohol intake frequency. 0.5 1.1 2.1 -0.0 -1.5
Comparative height size at age 10 0.1 0.4 0.6 0.4 -0.8
Number of full sisters 0.8 1.0 1.1 1.0 -1.0
Suffer from ‘nerves’ 1.9 3.0 5.6 -2.4 -0.7
Overall health rating 0.0 0.1 0.1 0.2 -0.3
Chest pain or discomfort 1.7 2.5 3.0 -1.7 -1.4
Had major operations 0.6 0.7 1.0 1.0 -0.6
Age at last live birth 0.2 0.3 0.4 -0.3 0.7
Family relationship satisfaction 2.5 3.0 5.4 0.8 -2.3
Leg pain on walking 3.1 3.9 4.1 2.0 -1.9
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.9 1.7 0.2 -1.3
Commuting to job workplace: Car/motor vehicle 0.6 0.7 0.8 0.9 0.8
Illness, injury, bereavement, stress in last 2 years 1.1 1.3 1.9 1.4 0.8
Medication: Aspirin 1.7 2.3 2.9 -1.3 1.7
Supplements: Vitamin C 1.0 1.1 2.3 1.5 0.1
Knee pain experienced in last month 0.6 1.0 1.3 0.8 -1.2
Hypertension (Self-reported) 0.4 1.0 1.9 0.4 1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.1 0.2 -0.2 0.5
Illnesses of father: Heart disease 0.9 1.2 2.1 1.5 -0.6
Illnesses of siblings: Diabetes 1.1 1.4 2.6 -0.4 1.6
Smoking status: Previous 0.7 1.1 1.7 0.7 -1.3
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.1 4.2 0.1 -2.0
Whole body fat-free mass 0.8 4.6 7.0 1.5 -2.6
Leg fat-free mass (right) 0.9 5.1 7.1 1.7 -2.7
Arm fat percentage (left) 0.0 0.0 0.0 -0.2 0.1
Average weekly red wine intake 1.1 1.6 2.8 1.7 -0.7
Handedness (chirality/laterality): Left-handed 1.2 1.5 2.7 -1.6 -0.5
Mood swings 1.5 2.7 4.2 1.1 -2.1
Loneliness, isolation 3.3 4.6 8.5 0.8 -2.9
Long-standing illness, disability or infirmity 0.3 0.5 0.9 1.0 0.2
Ever had bowel cancer screening 0.9 1.0 2.0 0.3 -1.4
Diabetes diagnosed by doctor 4.7 7.7 11.7 -1.9 3.4
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.1 2.0 0.5 1.4
Friendships satisfaction 1.5 1.9 3.7 -0.3 -1.9
Qualifications: nursing, teaching 2.0 3.1 3.3 -1.8 1.7
Commuting to job workplace: Walk 0.9 0.9 1.7 -1.3 0.4
Eye problems/disorders: Cataract 7.9 9.2 10.6 2.8 -3.3
Mouth/teeth dental problems: Mouth ulcers 0.8 1.3 2.3 -1.5 0.4
Medication for cholesterol 0.2 0.2 0.5 -0.7 0.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 0.4 0.3 0.6
Back pain experienced in last month 1.7 2.6 2.8 1.5 -1.7
Mineral and other dietary supplements 1.8 2.4 4.4 0.7 2.1
Breast cancer (self-reported) 0.9 1.1 1.8 1.3 0.6
Asthma (self-reported) 0.9 1.9 3.7 -1.9 0.0
Osteoporosis (self-reported) 1.1 1.4 2.1 -0.8 1.5
Osteoarthritis (self-reported) 0.1 0.1 0.2 0.1 0.5
Medication: Aspirin 1.6 2.1 2.8 -1.2 1.7
Medication: Gliclazide 0.1 0.1 0.2 0.4 -0.4
Illnesses of father: None of the above (group 1) 0.0 0.0 0.1 -0.1 0.3
Smoking status: Current 1.9 2.9 5.8 2.4 0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.0 1.9 1.4 -0.2
Whole body water mass 0.9 5.2 8.1 1.5 -2.9
Leg predicted mass (right) 0.9 5.0 7.2 1.7 -2.7
Arm fat mass (left) 0.1 0.3 0.5 0.4 -0.7
Number of self-reported non-cancer illnesses 0.7 1.1 1.8 -0.7 1.3
Average weekly champagne plus white wine intake 0.7 1.0 2.0 0.2 -1.4
Miserableness 3.5 6.1 8.4 1.9 -2.9
Guilty feelings 0.6 0.9 1.6 0.3 -1.3
Wears glasses or contact lenses 0.4 0.5 0.8 0.4 -0.9
Ever taken oral contraceptive pill 0.6 0.6 1.0 -0.5 1.0
Hearing aid user 1.0 1.1 1.3 0.9 1.2
Mother’s age at death 4.0 5.0 5.7 2.4 -2.1
Financial situation satisfaction 1.3 1.6 2.2 1.1 -1.5
Tinnitus: Yes, now most or all of the time 0.5 0.6 1.2 0.2 -1.1
Commuting to job workplace: Public transport 0.7 0.8 1.6 1.3 -0.0
Eye problems/disorders: Glaucoma 1.0 1.2 2.5 1.6 0.1
Medication: Blood pressure 0.8 1.5 3.1 1.8 0.0
Pain type(s) experienced in last month: Hip pain 0.5 0.7 1.1 0.4 -1.1
Supplements: Fish oil (including cod liver oil) 0.9 1.1 1.7 -1.3 -0.8
High cholesterol (Self-reported) 0.5 0.9 1.8 -0.1 1.4
Medication: Bendroflumethiazide 1.5 2.3 4.1 2.0 0.7
Medication: Paracetamol 0.1 0.1 0.2 -0.4 0.4
Medication: Lisinopril 1.3 1.7 2.9 0.8 1.7
Medication: Atorvastatin 2.7 3.3 6.7 2.6 -0.1
Illnesses of father: High blood pressure 0.3 0.4 0.8 -0.1 0.9
Alcohol drinker status: Never 1.5 1.7 3.1 -1.8 0.6
Ever smoked 0.7 1.2 1.7 1.3 -0.8
Basal metabolic rate 0.8 4.3 6.5 1.4 -2.5
Leg fat percentage (left) 0.0 0.1 0.2 -0.4 0.3
Arm fat-free mass (left) 0.8 4.1 6.6 1.3 -2.6
Number of operations (self-reported) 1.0 1.5 2.4 0.8 -1.6
Average weekly beer plus cider intake 0.2 0.3 0.5 0.0 0.7
Irritability 1.2 2.1 3.9 0.5 -2.0
Risk taking 1.5 2.1 3.5 1.9 0.9
Ever had prostate specific antigen (PSA) test 0.2 0.2 0.2 0.5 0.4
Fractured/broken bones in last 5 years 0.8 1.0 1.1 0.9 1.1
Age started oral contraceptive pill 0.1 0.1 0.2 0.3 0.4
Diastolic blood pressure, automated reading 0.2 0.8 1.4 0.4 1.2
Ever depressed for a whole week 0.7 0.8 1.5 0.4 -1.2
Unable to work because of sickness or disability 0.4 0.5 0.8 0.9 -0.4
Commuting to job workplace: Cycle 0.7 0.9 1.1 1.1 0.8
Myopia 0.2 0.3 0.3 -0.6 0.5
Vascular/heart problems diagnosed by doctor 0.4 1.0 2.0 -0.2 -1.4
Cholesterol lowering medication 0.8 1.2 2.4 -0.2 1.5
Medication: Omeprazole (e.g. Zanprol) 0.7 0.8 1.5 1.2 -0.4
Pain experienced in last month 0.1 0.2 0.2 -0.4 0.5
Supplements: Calcium 1.7 1.9 3.8 -0.1 -2.0
Basal cell carcinoma (self-reported) 0.1 0.1 0.1 0.3 0.2
Heart attack/myocardial infarction (self-reported) 0.6 0.8 0.9 -1.0 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.2 0.2 0.5 -0.0 0.7
Heart disease (siblings) 1.2 1.5 2.9 -1.7 0.3
Alcohol drinker status: Previous 1.5 1.7 2.6 0.9 -1.6
Pack years of smoking 0.4 0.6 1.0 -1.0 0.3
Impedance of whole body 0.2 1.2 2.2 -0.3 1.5
Leg fat mass (left) 0.1 0.4 0.8 0.2 -0.9
Arm predicted mass (left) 0.9 4.7 7.1 1.5 -2.7