Hub : Genes

KIF1C

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Esophagus Mucosa 0.1030 0.0440 7.5e-03 -0.004 NA 0.017 NA -0.004 8.1e-01 NA 2.4e-02 NA 7.3e-01
2 GTEx Skin Sun Exposed Lower leg 0.1250 0.0480 2.0e-03 0.015 NA 0.008 NA 0.004 1.9e-02 NA 6.4e-02 NA 1.3e-01
3 GTEx Thyroid 0.1520 0.0490 1.6e-04 0.066 NA 0.077 NA 0.064 8.3e-06 NA 1.8e-06 NA 1.1e-05
4 YFS Blood 0.0114 0.0060 1.5e-02 0.006 0.003 0.001 0.003 0.002 2.8e-03 2.2e-02 1.3e-01 0.024 5.3e-02
5 TCGA Kidney Renal Clear Cell Carcinoma 0.0365 0.0191 8.5e-04 0.004 0.026 0.031 NA 0.011 9.1e-02 5.8e-04 1.8e-04 NA 1.8e-02
6 TCGA Prostate Adenocarcinoma 0.0799 0.0377 3.4e-06 0.068 0.068 0.058 NA 0.062 1.1e-07 1.2e-07 1.1e-06 NA 4.4e-07
7 TCGA Stomach Adenocarcinoma 0.0720 0.0500 9.6e-03 0.016 0.026 0.028 NA 0.031 2.3e-02 5.1e-03 3.9e-03 NA 2.5e-03
8 TCGA Thyroid Carcinoma 0.0570 0.0350 1.1e-03 0.036 0.032 0.040 NA 0.037 2.0e-04 4.4e-04 7.7e-05 NA 1.6e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.7 1.0 4.4 0.7 -0.1 2.1 -1.3 0.6 0.2 -1.1 0.5
Bipolar Disorder or Schizophrenia 0.2 0.6 1.5 1.2 -1.2 0.9 0.0 -0.4 0.7 -0.4 -0.3
Depressed Affect (Nagel 2018) 0.5 1.1 4.5 -0.5 -0.6 1.5 -2.1 -0.2 -0.8 -0.2 0.8
Depression (Nagel 2018) 2.0 3.0 7.9 -0.6 -2.8 1.7 -2.7 -1.2 -1.8 -0.7 -0.0
Intelligence (Savage-Jansen 2018) 0.4 1.4 5.5 0.0 -0.3 -2.3 -0.2 -1.4 -0.1 0.3 -1.8
Neuroticism (Nagel 2018) 0.5 1.2 5.6 -0.9 -0.6 1.2 -2.4 0.1 -0.5 -0.4 1.0
Schizophrenia (2018) 0.4 0.9 2.4 0.7 -1.5 -0.5 1.2 -1.0 0.7 0.3 -0.8
Schizophrenia vs Biploar Disorder 0.7 0.9 3.3 0.3 -1.8 1.3 -0.7 0.0 -0.3 0.2 1.2
Worry (Nagel 2018) 0.8 1.8 4.9 -0.8 -0.7 1.8 -2.2 0.9 -0.4 -0.5 1.9
Alzheimer’s Disease (in mother) 1.3 1.5 5.6 0.7 -0.2 -0.5 1.7 0.4 1.6 2.4 0.1
Alzheimer’s Disease (in father) 2.1 2.2 8.8 0.9 -1.4 0.0 -0.4 0.9 2.0 3.0 1.2
Alzheimer’s Disease (including proxy) 4.0 5.8 21.6 2.0 -0.7 -0.0 2.2 1.2 3.5 4.6 1.3
Crohns Disease (2017) 0.6 1.4 4.7 0.6 1.6 0.4 0.8 0.7 1.4 2.2 0.5
Irritable Bowel Disease (IBD) 0.5 1.1 3.2 0.7 1.1 1.8 -0.5 0.8 0.7 0.9 1.3
Ulcerative Colitis (UC) 1.0 1.8 6.9 0.0 0.2 2.6 -1.7 0.9 -0.2 -0.6 1.9
Major Depression (MDD) 0.5 0.6 1.3 1.2 0.7 1.2 -0.6 0.7 -0.3 -0.7 0.4
Reaction Time 0.9 1.7 4.5 2.1 -0.2 1.4 -0.5 1.6 0.2 1.3 1.4
Verbal and Numeric Reasoning (VNR) 1.0 2.5 7.7 0.4 1.2 -2.8 2.0 -0.9 0.5 1.2 -2.0
Breast Cancer 0.4 1.0 3.9 0.6 1.7 -0.4 0.2 0.1 -0.9 -2.0 -0.2
Ovarian Cancer 2.2 3.0 6.7 1.2 1.6 1.6 1.4 2.6 1.9 1.2 1.9
Prostate Cancer 1.0 1.5 3.4 -0.2 -1.8 0.5 1.5 -0.1 1.8 1.5 0.6
Age at First Birth 0.7 1.0 3.2 0.6 0.6 1.4 -0.3 1.1 0.7 0.4 1.8
Bipolar Disorder (2011) 0.5 0.5 1.9 0.0 0.0 0.0 0.0 -1.4 0.5 0.6 -1.2
Body Mass Index (BMI) (2010) 1.7 2.3 5.4 0.4 2.3 -1.4 1.9 1.2 1.8 1.6 0.1
Coronary Artery Disease (CAD) 0.5 0.5 1.5 -1.1 0.3 -0.3 -0.3 0.8 0.1 -0.8 1.2
Crohns Disease (2012) 1.0 1.6 4.6 1.0 0.2 0.6 0.8 1.1 2.1 2.1 0.7
Mean Putamen Volume 0.3 0.3 1.0 -0.6 0.0 -0.4 -0.3 -0.4 -0.5 -1.0 -0.7
Fasting Glucose 0.5 0.6 1.8 0.6 -1.4 0.1 0.1 -0.0 1.0 1.1 -0.2
HbA1C 3.7 4.1 10.9 -1.8 -0.8 -3.3 0.7 -2.6 -0.5 -0.2 -3.2
HDL Cholesterol 0.3 0.5 1.4 -0.0 0.7 1.2 0.5 0.9 0.5 0.7 0.5
LDL Cholesterol 0.2 0.4 0.9 -0.2 0.2 -0.8 -1.0 0.3 -0.0 -0.9 0.8
Lupus 2.1 3.2 6.8 -0.9 0.6 -2.5 1.9 -2.2 -1.5 0.1 -2.6
Neuroticism (2016) 2.1 3.0 9.1 0.2 0.4 3.0 -1.5 1.9 -0.6 -0.7 2.8
Primary Biliary Cirrhosis 1.0 1.5 5.4 -0.5 -0.8 -0.0 -1.0 -1.0 -1.8 -2.3 -0.5
Rheumatoid Arthritis 2.6 3.6 9.6 1.0 -0.3 -2.4 2.2 -2.5 -0.8 -0.9 -3.1
Schizophrenia (2014) 0.3 0.6 3.7 0.0 -1.9 0.6 -0.4 -0.6 0.2 -0.3 0.5
Triglycerides 0.2 0.3 1.2 -0.3 -0.9 -1.1 -0.2 -0.4 -0.0 0.1 0.2
Type 2 Diabetes (T2D) (2012) 0.3 0.3 1.0 -0.7 -0.4 -0.8 0.3 0.0 0.1 1.0 0.0
Ulcerative Colitis 1.7 2.4 9.9 1.2 -0.6 3.1 -1.6 0.8 -0.0 -0.5 2.1
Blood Eosinophil Count 1.4 10.6 48.2 -6.9 -2.5 -4.5 2.1 -0.8 0.9 1.3 -1.5
Blood Platelet Count 1.3 15.1 44.9 4.5 -0.7 6.7 -4.3 4.6 -2.3 -0.9 3.1
Blood Red Count 1.3 12.6 26.9 4.0 1.8 1.9 3.4 4.1 5.2 3.0 3.6
Blood White Count 2.8 20.4 62.6 4.1 3.5 -1.9 7.9 1.9 4.1 6.9 -0.9
Heel T-Score 0.5 3.6 11.7 1.8 -1.4 -0.5 3.4 0.0 2.4 2.5 0.3
BMI 1.5 8.8 20.8 3.1 0.7 -1.6 3.8 1.4 4.5 4.6 -0.2
Height 0.4 7.7 17.6 -1.8 1.9 3.3 -2.9 3.4 -0.6 -2.4 4.2
Waist Hip Ratio (WHR) 0.2 0.8 2.8 0.1 0.1 0.3 1.0 0.7 1.7 0.8 1.0
Systolic Blood Pressure 0.2 1.1 3.3 0.2 1.6 -0.3 1.8 0.5 1.3 0.7 -0.1
Smoking Status 2.5 6.0 18.5 -1.6 -0.8 -4.3 1.2 -3.2 0.0 0.6 -3.8
Allergy or Eczema 0.2 0.5 1.9 -1.0 -1.4 -0.6 -0.6 -0.0 0.3 0.6 -0.1
Cardiovascular Disease 0.6 2.1 4.0 -0.5 1.4 -2.0 1.9 -0.0 1.7 1.5 -1.4
Hypothyroidism (self reported) 0.9 2.0 11.2 -0.7 3.3 -1.2 1.3 0.4 -0.3 0.4 -0.9
Respiratory disease 0.6 1.4 2.9 -1.7 0.4 -0.5 -1.1 -0.6 -1.4 -1.6 -1.2
Type 2 Diabetes (T2D) (2018) 1.5 2.7 6.5 -0.2 0.0 -2.0 2.1 -0.3 2.1 2.5 -1.4
Lung FEV1/FVC ratio 0.8 4.1 14.8 2.1 -3.9 0.3 1.9 -0.7 2.5 1.6 -0.5
Lung FVC 0.1 0.6 1.8 0.5 0.8 -0.6 1.4 -0.7 -0.2 -0.1 -1.2
Neuroticism 0.2 0.5 2.4 -0.6 -0.9 0.3 -1.5 -0.2 -0.2 -0.2 0.3
Chronotype (morning person) 2.6 6.1 10.2 -3.0 -3.1 -0.1 -3.2 -2.1 -2.5 -2.6 -1.3
Hair Pigment 0.0 0.3 0.6 -0.5 0.7 -0.5 -0.0 -0.8 0.2 -0.7 -0.6
Tanning 0.0 0.3 0.8 -0.4 0.2 -0.7 0.2 0.3 0.9 0.8 -0.3
Hand grip strength (left) 0.2 0.5 1.5 0.6 1.2 0.4 1.2 0.5 0.7 0.5 0.1
Number of treatments/medications taken 0.9 1.6 4.1 0.1 2.0 -1.3 1.1 -0.4 -1.4 -0.6 -1.8
Average weekly spirits intake 0.3 0.4 1.3 0.1 -0.3 -1.2 -1.1 -0.3 -0.2 -0.5 -0.3
Sensitivity / hurt feelings 0.4 0.7 2.4 -1.4 -0.2 -0.0 -1.6 -0.7 -0.7 -0.5 -0.5
Frequency of depressed mood in last 2 weeks 0.6 0.8 3.2 -1.0 -1.0 0.2 -1.8 -0.8 -0.8 -0.2 -0.2
Hearing difficulty/problems: Yes 1.3 2.0 5.6 -2.0 -1.5 -0.3 -2.4 -0.7 -1.1 -1.5 -0.1
Relative age of first facial hair 0.1 0.2 0.9 0.7 0.3 -0.5 0.9 -0.2 0.0 -0.1 -0.2
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 1.5 0.6 0.1 -0.8 0.4 -0.2 -0.2 1.2 -0.4
Ever used hormone-replacement therapy (HRT) 3.2 4.1 7.4 -0.5 -1.8 -2.0 -1.3 -2.7 -1.8 -2.6 -2.4
Ever had hysterectomy (womb removed) 1.3 1.4 4.0 0.2 -0.5 1.7 -1.7 0.3 -0.9 -2.0 0.7
Systolic blood pressure, automated reading 0.5 1.4 3.3 0.3 -0.4 -1.8 1.8 -1.2 0.4 0.5 -1.7
Eye problems/disorders: Diabetes related eye disease 3.0 3.3 6.6 2.5 2.1 0.3 1.4 1.7 2.6 2.0 0.8
Angina 0.3 0.4 1.8 0.5 0.1 1.3 -0.4 -0.0 -0.2 -0.8 -0.2
Medication for hormone replacement therapy 0.8 0.9 1.6 1.2 1.3 -1.0 1.0 -0.6 0.2 -0.1 -1.2
Vitamin and mineral supplements 0.5 0.7 2.4 0.3 0.7 -0.6 1.4 0.4 1.5 0.7 0.0
Supplements: Zinc 0.6 0.6 1.2 -1.1 -0.8 0.4 -0.5 -0.6 -1.0 -0.6 -1.1
Medication: Co-codamol 1.6 1.8 7.7 -0.7 -1.6 -0.7 -2.8 -0.9 -1.4 -0.5 -0.5
Medication: Metformin 0.7 0.9 2.4 -0.6 0.2 -1.6 0.5 -0.2 0.8 1.4 -1.4
Diabetes (father) 0.7 0.9 5.3 -2.3 0.5 -0.3 0.2 0.7 0.8 0.5 0.3
Diabetes (mother) 0.4 0.5 1.4 -0.8 -0.1 -0.1 -1.1 -0.4 -1.2 -0.9 -0.3
Severe depression (siblings) 0.5 0.6 1.2 0.4 -1.0 0.3 -0.6 0.6 1.1 1.1 0.6
Pack years adult smoking proportion 0.2 0.3 0.8 -0.4 0.9 0.5 0.4 -0.2 0.6 -0.6 -0.6
Impedance of leg (right) 0.3 1.6 3.4 -1.7 -0.3 1.2 -1.4 -0.2 -1.8 -1.6 0.5
Leg fat-free mass (left) 0.9 4.5 12.7 1.5 1.5 -0.5 1.8 2.2 3.6 3.1 1.1
Trunk fat percentage 0.8 3.0 7.4 1.0 0.9 -1.5 2.3 0.9 2.5 2.7 -0.5
Hand grip strength (right) 0.7 1.9 3.6 1.4 0.2 1.1 1.2 1.3 1.9 1.7 1.4
Townsend deprivation index at recruitment 0.2 0.3 1.1 0.7 0.1 0.5 0.5 -0.0 1.0 -0.4 -0.2
Current tobacco smoking 2.1 3.5 9.6 -1.6 -1.2 -3.1 0.2 -2.1 -0.1 1.7 -2.6
Average weekly fortified wine intake 0.6 0.7 1.8 0.7 -0.6 1.3 -0.1 1.1 -0.1 0.9 1.0
Maternal smoking around birth 0.6 0.9 2.3 1.1 -0.5 -0.4 1.5 -0.2 1.4 0.9 -0.7
Fed-up feelings 0.5 0.9 3.5 -0.3 -0.1 1.9 -0.4 0.6 1.1 0.1 1.2
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.4 4.6 0.2 -2.1 1.0 -1.8 -1.0 -1.1 -0.4 -0.0
Relative age voice broke 0.2 0.3 0.5 -0.7 -0.6 0.1 0.5 -0.6 -0.4 -0.7 -0.3
Taking other prescription medications 2.3 3.6 7.1 -1.4 1.6 -2.5 0.4 -1.5 -2.7 -1.3 -2.5
Age when periods started (menarche) 1.4 3.3 12.0 -1.5 0.1 -0.7 -1.4 -1.7 -2.3 -3.5 -1.0
Bilateral oophorectomy (both ovaries removed) 0.9 1.0 1.6 1.1 -1.1 1.2 -0.5 0.5 1.0 1.0 1.2
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.6 2.9 0.8 -1.7 -1.4 1.5 -1.6 0.8 1.1 -1.0
Tinnitus: Yes, but not now, but have in the past 1.3 1.4 3.5 1.5 -0.1 0.2 1.0 1.9 1.5 0.9 1.3
Qualifications: CSEs or equivalent 1.7 2.3 4.8 1.2 1.8 -1.5 2.1 -0.0 0.6 2.2 -1.3
Serious illness, injury or assault to yourself 1.9 2.4 9.3 0.3 -1.1 -1.1 1.9 0.1 1.8 3.0 -0.4
High blood pressure 0.4 1.0 2.3 -1.0 0.7 -1.4 0.5 -0.7 -0.9 -0.8 -1.5
Hayfever, allergic rhinitis or eczema 0.2 0.5 2.1 -0.1 -1.4 0.2 -1.2 0.0 -0.1 0.4 0.2
Multivitamins +/- minerals 1.0 1.3 3.4 0.0 -0.9 1.7 -1.8 0.4 -1.4 -0.7 1.0
Stomach or abdominal pain in last month 0.1 0.1 0.3 -0.5 0.1 -0.6 -0.4 0.1 0.3 0.4 -0.2
Supplements: Glucosamine 0.6 0.8 2.4 1.5 0.2 1.1 -1.1 0.7 -0.4 0.0 1.1
Diverticular disease/diverticulitis (self-reported) 1.0 1.2 4.0 1.5 2.0 -0.0 1.6 0.3 0.0 -0.5 -0.5
Medication: Atenolol 1.1 1.3 4.5 -0.7 -1.2 1.3 -2.1 0.5 -0.8 -0.7 1.1
Medication: Levothyroxine sodium 1.2 2.0 9.5 -0.8 3.1 -1.6 0.9 0.3 -0.2 0.4 -1.4
Sitting height 0.3 2.1 6.0 -0.9 0.3 2.1 -0.4 1.9 1.3 0.2 2.5
Chronic bronchitis/emphysema (father) 0.2 0.2 0.7 0.1 -0.9 0.3 -0.0 -0.2 -0.9 -0.2 -0.3
High blood pressure (mother) 1.5 2.0 6.1 -1.2 -2.5 -1.5 -0.9 -1.7 -1.0 0.2 -1.3
Body mass index (BMI) 1.2 5.2 12.0 1.9 0.5 -2.1 3.0 0.5 3.4 3.5 -1.0
Impedance of leg (left) 0.4 1.7 3.7 -1.7 -0.6 1.5 -1.2 -0.4 -1.9 -1.6 0.6
Leg predicted mass (left) 0.9 4.5 12.9 1.4 1.5 -0.6 1.9 2.1 3.6 3.1 1.0
Trunk fat mass 0.9 3.7 9.1 0.9 1.3 -1.3 2.3 1.4 3.0 3.0 -0.0
Waist circumference 1.2 4.3 11.2 1.5 0.7 -1.3 2.7 1.0 3.3 3.2 -0.2
Number of incorrect matches in round 0.7 1.1 2.3 -0.7 -1.5 0.5 -1.5 -0.7 -1.3 -1.1 -0.0
Past tobacco smoking 2.7 4.9 12.0 1.3 -0.4 3.2 -1.2 2.8 1.0 2.0 3.5
Alcohol usually taken with meals 0.7 1.1 2.0 -0.9 0.6 1.1 -1.1 1.2 -0.8 -0.6 1.4
Nervous feelings 0.5 0.8 2.1 -0.3 0.3 1.3 -1.4 0.5 -0.9 -0.8 1.1
Frequency of tenseness / restlessness in last 2 weeks 1.9 2.9 7.7 0.4 -0.3 2.5 -2.5 1.7 -0.2 -0.4 2.8
Hearing difficulty/problems with background noise 0.2 0.4 1.4 0.4 -1.1 0.2 -1.2 -0.1 -0.0 0.3 0.4
Hair/balding pattern: Pattern 2 0.4 0.6 1.8 0.4 -1.4 0.1 0.7 -0.1 1.4 0.3 0.0
Had menopause 1.4 1.8 6.0 0.4 -1.1 0.4 -1.3 -0.9 -1.9 -2.5 -0.7
Had other major operations 0.7 0.8 1.7 -1.0 -0.9 -0.1 -1.0 -1.3 -1.1 -0.3 -0.8
Forced vital capacity (FVC) 0.4 1.4 3.2 -0.2 0.9 1.1 1.2 1.0 1.8 1.3 1.4
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.7 2.5 0.3 -1.6 -0.6 0.6 -1.4 0.5 0.4 -0.5
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 0.8 0.9 0.9 0.5 -0.8 0.9 0.8 0.4 0.9
Qualifications: None of the above 1.2 2.5 8.9 -0.5 0.7 -0.8 -0.4 -1.3 -2.2 -3.0 -1.8
Financial difficulties in last 2 years 0.9 1.2 2.0 1.2 -0.3 1.2 1.0 0.9 1.1 1.4 1.4
Mouth/teeth dental problems 0.6 0.9 1.7 -1.2 0.8 -0.3 1.2 0.8 1.3 0.9 0.6
Heart attack 0.2 0.3 1.1 -0.1 1.1 -0.0 -0.3 0.3 -0.6 -0.8 0.2
Allergy 0.3 0.7 2.8 0.2 0.5 -0.3 1.7 0.0 1.4 0.5 0.2
Pain all over the body in last month 0.8 0.9 2.7 1.0 -0.8 0.8 -0.2 1.0 0.9 1.6 0.7
Diabetes (self-reported) 1.1 1.7 3.5 0.7 1.2 -1.1 1.8 0.4 1.9 1.7 -0.9
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 0.9 1.0 0.1 -0.3 -0.5 0.5 -0.6 -0.6 0.1
Medication: Ramipril 0.2 0.3 0.8 -0.9 0.9 -0.1 -0.3 0.3 -0.5 0.1 -0.6
Medication: Simvastatin 0.3 0.4 1.2 -1.1 -0.1 -0.7 -0.9 -0.1 -0.5 -0.7 -0.1
Fluid intelligence score 0.4 0.9 2.4 0.9 0.5 -0.2 1.6 0.4 1.4 1.1 0.2
Illnesses of siblings 1.9 2.6 5.8 1.1 -0.1 1.2 0.3 1.5 2.4 2.4 2.1
Neuroticism score 0.2 0.5 1.2 -0.2 0.2 0.5 -0.6 0.4 0.9 1.1 0.9
Weight 0.9 4.6 13.0 1.5 1.3 -0.4 2.2 2.0 3.6 3.1 0.9
Impedance of arm (right) 0.4 1.9 4.5 -1.3 0.2 1.4 -2.1 0.8 -1.9 -1.2 1.2
Arm fat percentage (right) 1.3 5.2 13.5 1.2 1.3 -2.2 2.9 1.1 3.1 3.7 -0.7
Trunk fat-free mass 0.6 3.6 10.4 0.7 1.4 0.3 1.3 2.3 3.2 2.4 1.8
Hip circumference 0.9 4.1 11.3 1.1 0.8 -1.1 2.3 1.4 3.3 3.4 0.3
Time employed in main current job 0.4 0.5 1.1 -0.9 -1.1 -0.6 0.4 -0.3 1.0 -0.0 -0.3
Alcohol intake versus 10 years previously 0.7 1.0 3.2 1.8 1.2 1.4 0.2 0.5 0.0 -1.2 0.2
Father’s age at death 1.5 2.0 5.8 1.2 -0.7 2.4 -1.0 1.3 0.5 -0.2 2.4
Worrier / anxious feelings 0.8 1.5 4.2 0.0 -0.7 2.1 -0.8 1.1 0.9 0.7 2.1
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 1.8 -1.3 -0.6 -0.3 -1.2 -0.1 -0.2 0.5 -0.0
Falls in the last year 0.7 0.9 3.0 -1.0 -0.8 -1.3 -0.3 -0.8 -0.8 -0.1 -1.7
Hair/balding pattern: Pattern 3 1.0 1.5 3.1 1.6 1.7 0.7 0.8 1.0 1.0 1.8 0.6
Number of live births 0.9 1.3 3.5 1.2 1.9 -1.0 1.6 0.0 0.8 0.1 -1.0
Forced expiratory volume in 1-second (FEV1) 0.9 2.9 8.2 1.1 0.0 1.1 2.1 1.0 2.9 2.2 1.4
Pulse rate 1.3 2.2 4.7 -1.0 -1.7 2.2 -2.0 0.3 -0.8 -1.7 1.0
Happiness 0.6 0.7 3.2 -0.5 0.5 0.3 -1.8 -0.5 -1.0 -0.9 0.3
Noisy workplace 0.7 0.9 2.9 1.7 0.6 1.2 -0.1 1.0 0.3 -0.2 1.2
Qualifications: A levels/AS levels or equivalent 0.3 0.6 2.2 1.1 -0.2 0.1 -0.1 0.8 0.6 0.6 1.5
Serious illness, injury or assault of a close relative in last 2 years 1.3 1.5 3.4 0.0 0.2 -1.5 1.7 -0.4 1.7 1.9 -0.3
Mouth/teeth dental problems: Dentures 1.9 3.3 9.9 0.2 -1.2 -0.5 -2.3 -1.6 -3.1 -2.1 -1.5
Asthma 0.6 1.3 2.6 -1.4 0.9 -1.4 0.4 -0.9 -1.2 -0.5 -1.6
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.7 2.7 1.3 0.1 0.2 1.6 -0.2 0.7 0.9 -0.3
Medication: Cholesterol lowering 0.2 0.3 1.0 -0.4 0.3 -0.6 -0.2 -0.6 -0.9 -0.1 -1.0
Depression (self-reported) 0.7 0.8 3.4 -0.3 -1.3 0.7 -1.8 0.4 0.0 -0.1 0.9
Medication: Lansoprazole 0.4 0.4 1.2 -0.4 0.5 -1.1 0.5 -0.4 0.2 0.8 -0.8
Prospective memory result 3.1 3.8 5.9 -2.3 -2.4 -1.6 -2.4 -1.7 -1.9 -1.9 -1.0
Lung cancer (father) 3.8 4.4 9.4 -2.6 -2.9 -1.2 -0.2 -3.1 -1.9 -1.6 -1.8
Illnesses of mother 2.7 3.3 10.3 1.5 0.8 3.2 -0.1 2.1 1.2 0.7 2.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 2.0 4.7 1.0 0.5 1.5 1.6 1.2 2.2 1.4 1.6
Pulse wave Arterial Stiffness index 0.3 0.3 1.6 0.4 0.5 0.7 1.3 0.2 0.3 0.1 -0.1
Impedance of arm (left) 0.4 2.0 5.2 -1.2 -0.2 1.2 -2.2 0.2 -2.3 -1.5 0.7
Arm fat mass (right) 1.2 4.9 11.8 1.5 1.3 -1.6 2.6 1.4 3.4 3.4 -0.2
Trunk predicted mass 0.6 3.4 10.0 0.7 1.3 0.2 1.2 2.2 3.2 2.3 1.8
Standing height 0.6 5.7 15.8 -0.7 2.0 3.2 -1.4 3.5 0.8 -0.7 4.0
Length of working week for main job 0.7 0.8 2.0 -0.2 0.2 -1.1 0.6 -0.8 0.3 1.3 -1.4
Exposure to tobacco smoke at home 0.5 0.6 1.8 -1.3 -1.1 0.6 -1.0 -0.0 -0.1 -0.3 -0.0
Breastfed as a baby 0.8 1.0 3.7 0.8 -0.3 0.9 -1.0 -0.2 -1.1 -1.9 -0.2
Tense / ‘highly strung’ 1.0 1.6 7.3 -0.4 -1.4 1.1 -2.7 -0.0 -0.6 -0.9 1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 1.2 -0.2 0.6 0.9 -1.1 1.0 -0.4 0.4 1.1
Hair/balding pattern: Pattern 4 0.7 1.8 4.1 -0.3 -0.5 -1.2 1.2 -1.9 -1.1 -1.5 -2.0
Birth weight of first child 0.4 0.7 2.0 0.0 -0.7 1.4 -0.8 0.9 0.2 0.5 1.2
Peak expiratory flow (PEF) 0.4 0.9 2.9 0.7 -0.9 0.4 1.7 -0.4 1.2 1.1 0.2
Pulse wave reflection index 1.7 2.1 6.3 -1.4 -0.1 -1.7 1.1 -2.0 -0.1 0.2 -2.5
Ever highly irritable/argumentative for 2 days 1.8 2.2 7.8 0.8 1.4 0.7 0.7 1.6 2.8 1.5 1.2
Loud music exposure frequency 0.9 1.0 2.5 0.6 0.8 -0.5 1.3 0.7 1.6 1.2 0.6
Qualifications: O levels/GCSEs or equivalent 2.0 3.2 7.0 2.0 1.1 0.7 2.1 1.4 2.3 2.7 1.1
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 2.1 0.8 1.4 0.2 -0.5 0.2 -0.2 0.3 0.0
Blood clot in the leg (DVT) 0.1 0.1 0.5 0.7 0.1 -0.2 -0.1 -0.1 -0.0 0.2 -0.2
Medication: Paracetamol 1.3 2.2 4.5 2.1 1.2 -0.1 2.1 0.5 2.1 1.6 0.0
Headache pain in last month 0.5 0.9 3.8 -0.1 0.2 -1.9 0.1 -1.2 -0.1 0.4 -1.2
Medication for cholesterol, blood pressure or diabetes 0.8 1.3 2.7 1.0 0.4 1.3 0.5 1.4 1.4 1.0 1.7
Glaucoma (self-reported) 1.7 2.0 8.3 -0.7 -0.3 -2.9 0.7 -1.5 -0.0 0.1 -2.0
Gout (self-reported) 0.9 1.2 5.5 0.8 2.3 -0.8 0.8 -0.3 -0.7 -0.6 -1.4
Hypothyroidism/myxoedema (self-reported) 1.0 1.9 10.5 -0.1 3.2 -1.2 1.2 1.0 -0.0 0.5 -0.6
Medication: Amlodipine 1.1 1.6 4.1 -0.5 -1.0 -0.1 -1.9 -1.1 -1.4 -2.0 -0.7
Medication: Ventolin 100micrograms inhaler 1.1 1.4 2.3 -1.5 1.0 1.0 -1.4 1.0 -0.4 -1.4 1.2
Birth weight 0.8 1.7 5.2 -0.2 -0.7 1.2 -1.3 1.7 0.8 1.0 2.3
Chronic bronchitis/emphysema (mother) 1.0 1.2 6.4 1.0 2.5 0.3 0.7 0.9 0.2 -0.9 0.2
High blood pressure (siblings) 1.3 1.9 4.2 -0.3 1.4 -0.6 1.1 -0.9 -1.9 -1.7 -2.1
Forced vital capacity (FVC), Best measure 0.2 0.8 2.4 -0.0 0.5 1.5 0.5 0.7 0.9 0.4 1.4
Body fat percentage 0.9 3.7 9.1 1.0 0.8 -2.0 2.6 0.7 2.7 3.0 -0.8
Leg fat percentage (right) 1.1 3.9 9.2 0.9 0.2 -2.3 2.7 0.0 2.5 3.0 -1.3
Arm fat-free mass (right) 0.6 3.2 10.7 1.1 0.9 -0.2 2.0 1.6 3.3 2.3 1.0
Exposure to tobacco smoke outside home 0.1 0.2 0.4 0.5 0.1 -0.2 0.6 -0.6 0.4 0.0 -0.7
Comparative body size at age 10 0.1 0.2 1.0 -0.3 0.1 0.2 -0.5 -0.1 -1.0 -0.5 -0.1
Number of full brothers 0.4 0.4 0.7 0.8 -0.8 0.4 0.1 0.8 0.7 0.8 0.6
Worry too long after embarrassment 0.9 1.5 3.3 -0.4 1.8 0.6 -0.7 1.7 1.1 0.4 1.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.8 2.0 -0.6 -0.1 0.5 -1.4 1.0 0.3 1.0 1.3
Wheeze or whistling in the chest in last year 0.7 1.3 2.3 -1.1 -0.6 -1.1 -1.5 -0.9 -1.5 -1.1 -0.9
Number of children fathered 2.9 3.3 8.8 1.8 -0.1 -0.9 3.0 -0.5 2.3 2.6 -1.1
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 1.8 1.1 0.9 0.5 -0.3 1.3 0.8 -0.1 0.7
Age at first live birth 0.6 1.1 2.6 0.3 -0.9 0.6 1.0 0.2 1.6 1.5 1.1
Pulse wave peak to peak time 0.2 0.3 1.6 -0.3 -0.2 -0.3 -1.3 0.2 -0.2 -0.2 0.5
Health satisfaction 2.2 2.9 12.6 -1.2 -1.1 0.8 -3.6 -0.5 -2.0 -1.6 0.5
Shortness of breath walking on level ground 0.4 0.5 1.5 0.5 0.0 0.9 -0.7 0.7 -0.1 -0.0 1.2
Qualifications: College or University degree 0.3 0.9 2.5 -1.6 -0.6 0.2 -0.1 0.6 0.8 1.1 1.3
Eye problems/disorders: None of the above 1.5 1.7 5.4 0.0 0.6 2.0 -0.6 1.8 0.4 0.4 2.3
Mouth/teeth dental problems: Loose teeth 0.7 0.9 1.6 1.3 -1.1 1.2 -0.9 0.5 -0.4 -0.5 1.1
Emphysema/chronic bronchitis 0.1 0.1 0.4 -0.3 0.1 0.2 -0.6 0.3 -0.6 -0.2 0.3
Medication for pain relief, constipation, heartburn 0.4 0.7 2.1 -0.5 -0.8 1.1 -0.9 0.6 0.1 0.2 1.4
Neck or shoulder pain in last month 0.8 1.1 5.7 0.7 2.4 -0.3 0.9 -0.3 -1.2 -0.2 -0.6
Medication: Blood pressure 0.7 1.2 2.0 -1.3 -0.3 -0.9 -0.2 -1.2 -1.4 -1.3 -1.4
Angina (self-reported) 0.3 0.5 2.1 0.8 0.4 1.4 -0.3 0.2 -0.1 -0.8 -0.1
Migraine (self-reported) 0.4 0.5 1.3 0.6 0.4 -0.3 0.2 -0.9 -1.2 0.2 -0.9
Medication: Ibuprofen 1.3 1.6 3.8 1.9 0.4 0.4 2.0 0.4 1.5 1.6 0.1
Medication: Allopurinol 1.3 1.7 4.1 0.0 2.0 -1.4 1.6 -0.6 -0.1 -0.4 -2.0
Medication: Omeprazole 0.6 0.7 2.6 -0.3 -0.2 0.0 -0.9 -0.7 -0.8 -1.6 -1.0
Medication: Seretide 50 evohaler 0.1 0.1 0.5 -0.4 0.7 0.1 0.5 0.1 -0.2 -0.2 -0.3
Mean time to correctly identify matches 0.7 1.3 3.1 1.8 -0.7 1.3 -1.5 1.0 -1.0 -0.5 0.8
Heart disease (mother) 1.8 2.2 8.4 -1.5 -0.2 -2.9 -0.3 -1.5 -0.9 -0.6 -1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 1.9 0.1 0.7 -0.4 0.6 -0.8 -0.6 -0.8 -1.4
Whole body fat mass 0.9 3.8 9.0 1.1 1.2 -1.6 2.4 1.2 3.0 3.0 -0.3
Leg fat mass (right) 1.4 5.3 13.2 1.3 0.9 -2.0 3.1 0.9 3.5 3.6 -0.6
Arm predicted mass (right) 0.5 2.8 8.8 1.1 1.1 -0.3 2.0 1.4 3.0 2.0 0.8
Pulse rate, automated reading 2.2 7.1 18.1 -0.2 -0.5 3.8 -4.2 2.2 -2.1 -2.2 3.2
Alcohol intake frequency. 0.5 1.2 4.0 0.7 2.0 0.9 0.5 1.4 1.2 0.0 0.8
Comparative height size at age 10 0.2 1.1 2.7 -1.2 -0.4 1.1 -1.6 0.8 -0.3 -0.6 1.4
Number of full sisters 0.5 0.7 1.8 -1.0 1.3 0.7 -0.3 1.1 -0.2 -0.5 0.4
Suffer from ‘nerves’ 0.7 1.1 4.2 -0.7 -0.3 1.3 -0.5 1.0 1.0 0.7 2.0
Overall health rating 0.7 1.6 4.2 -1.8 0.1 -0.5 -2.1 -0.6 -1.9 -1.0 -0.4
Chest pain or discomfort 0.1 0.2 0.6 0.2 0.4 0.8 -0.6 0.7 0.0 -0.2 0.1
Had major operations 0.3 0.4 0.9 -0.9 0.0 -0.3 -0.9 -0.7 -0.9 -0.0 -0.2
Age at last live birth 0.8 1.1 3.1 -0.1 -1.3 -0.7 1.3 -0.4 1.8 1.4 0.3
Family relationship satisfaction 1.5 1.9 7.6 -1.9 -0.2 0.7 -2.8 -0.2 -0.9 -1.5 0.4
Leg pain on walking 0.4 0.5 1.1 0.3 0.2 0.5 -1.0 1.1 0.4 0.6 1.0
Qualifications: NVQ or HND or HNC or equivalent 1.4 1.7 8.3 1.5 -1.0 -0.7 0.9 -0.1 0.9 2.9 -0.1
Commuting to job workplace: Car/motor vehicle 1.5 1.8 6.7 0.6 0.3 -1.3 2.6 -0.1 1.5 1.4 -0.9
Illness, injury, bereavement, stress in last 2 years 3.2 3.9 11.5 -1.9 0.7 0.4 -2.4 -1.0 -2.8 -3.4 -0.8
Medication: Aspirin 1.8 2.3 5.1 -1.4 -0.8 -0.7 -1.1 -1.8 -2.2 -1.9 -1.6
Supplements: Vitamin C 0.2 0.2 1.5 -1.2 0.2 0.3 -0.2 -0.1 -0.3 0.2 -0.4
Knee pain experienced in last month 0.2 0.3 0.7 -0.3 0.5 0.4 -0.4 -0.6 -0.4 -0.8 -0.4
Hypertension (Self-reported) 0.4 1.0 3.4 -0.8 0.9 -1.8 1.0 -0.6 -0.3 -0.0 -1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 2.0 -0.5 0.2 -0.3 -0.5 -0.3 -0.9 -1.4 -0.7
Illnesses of father: Heart disease 0.7 1.0 2.3 -1.1 -0.5 -0.8 -1.5 -0.9 -0.9 -0.7 -1.0
Illnesses of siblings: Diabetes 2.0 2.4 4.7 -0.9 1.2 -1.9 -0.3 -1.3 -1.7 -2.0 -2.2
Smoking status: Previous 1.7 2.5 5.1 -0.4 1.3 -2.3 1.2 -1.6 -0.8 -2.0 -2.1
Forced expiratory volume in 1-second (FEV1), predicted 0.8 1.6 5.6 -0.5 0.7 1.3 0.0 2.0 0.6 0.6 2.4
Whole body fat-free mass 0.7 4.2 12.5 1.1 1.4 -0.1 1.8 2.2 3.5 2.7 1.5
Leg fat-free mass (right) 0.9 4.6 12.7 1.6 1.5 -0.1 2.0 2.2 3.6 3.0 1.2
Arm fat percentage (left) 1.2 4.7 13.1 1.2 1.0 -2.1 2.7 0.9 3.0 3.6 -0.8
Average weekly red wine intake 0.9 1.3 3.1 -0.8 0.1 1.1 -1.5 1.3 -1.0 -0.3 1.8
Handedness (chirality/laterality): Left-handed 0.6 0.7 3.1 -1.8 0.5 -0.2 -0.5 -0.2 -1.1 -0.7 -0.2
Mood swings 0.3 0.5 1.6 -0.2 -0.7 0.7 -1.2 0.0 0.3 0.7 1.0
Loneliness, isolation 1.1 1.5 5.2 0.7 0.9 2.3 -0.3 1.2 1.1 1.0 1.3
Long-standing illness, disability or infirmity 0.8 1.2 3.6 -0.5 0.1 -1.1 -1.5 -1.0 -1.9 -0.6 -1.0
Ever had bowel cancer screening 2.0 2.3 5.2 -0.9 -0.5 -1.2 -0.8 -1.5 -2.2 -2.3 -1.8
Diabetes diagnosed by doctor 1.1 1.8 3.1 0.8 1.0 -1.4 1.7 0.0 1.8 1.7 -1.4
Ever had stillbirth, spontaneous miscarriage or termination 1.6 1.7 3.5 -1.9 -1.1 -0.5 -1.6 -1.1 -1.8 -0.9 -1.0
Friendships satisfaction 0.9 1.1 2.6 -1.0 1.4 0.1 -1.6 -0.4 -1.3 -1.4 -0.2
Qualifications: nursing, teaching 0.8 1.2 4.6 -0.5 -2.1 0.8 -1.5 -0.3 -0.7 -0.8 0.6
Commuting to job workplace: Walk 1.1 1.1 3.3 0.0 0.2 1.0 -1.8 0.5 -0.9 -1.7 1.0
Eye problems/disorders: Cataract 1.0 1.2 5.0 -0.4 -2.2 -0.4 -0.9 -1.3 -0.4 -0.8 -1.0
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 0.8 0.9 -0.9 0.0 -0.1 -0.6 0.5 0.4 0.0
Medication for cholesterol 0.4 0.6 1.3 -0.7 -1.1 1.1 -0.8 -0.1 -0.9 -0.3 0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 2.0 0.6 -0.9 -0.2 0.2 -1.4 -1.1 -0.1 -1.0
Back pain experienced in last month 0.3 0.4 2.2 0.2 1.5 -0.4 0.1 0.1 0.2 -0.4 -0.7
Mineral and other dietary supplements 1.3 1.7 4.6 -1.5 0.9 -2.1 1.3 -1.1 0.7 0.4 -1.5
Breast cancer (self-reported) 0.5 0.6 1.8 -0.9 -0.2 -1.4 0.0 -0.9 -0.2 -0.7 -0.8
Asthma (self-reported) 0.6 1.1 2.2 -1.4 0.9 -1.3 0.1 -0.8 -1.2 -0.6 -1.5
Osteoporosis (self-reported) 1.3 1.6 3.9 0.9 1.4 0.7 -1.4 -0.1 -2.0 -1.9 -0.5
Osteoarthritis (self-reported) 0.4 0.6 1.7 1.3 0.4 -1.2 0.3 0.0 0.3 1.0 -0.2
Medication: Aspirin 1.6 2.0 3.7 -1.6 -1.2 -0.8 -1.0 -1.7 -1.9 -1.4 -1.4
Medication: Gliclazide 0.5 0.6 1.8 -0.7 1.0 -1.4 -0.8 0.3 -0.6 -0.3 -0.4
Illnesses of father: None of the above (group 1) 1.9 2.3 5.5 2.2 1.7 2.3 0.5 1.3 -0.6 -1.2 1.3
Smoking status: Current 2.1 3.3 8.0 -1.6 -1.3 -2.8 0.1 -2.2 -0.1 1.5 -2.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 1.4 1.2 -1.1 0.7 0.5 -0.4 0.5 -0.0 0.1
Whole body water mass 0.7 4.1 12.3 1.2 1.4 0.0 1.7 2.2 3.5 2.6 1.5
Leg predicted mass (right) 0.9 4.7 13.4 1.6 1.4 -0.1 2.1 2.2 3.7 3.1 1.2
Arm fat mass (left) 1.2 4.8 12.1 1.4 1.2 -1.6 2.7 1.3 3.4 3.5 -0.2
Number of self-reported non-cancer illnesses 1.2 2.1 5.2 -0.2 1.2 -1.6 -0.2 -1.1 -2.1 -1.3 -2.3
Average weekly champagne plus white wine intake 0.9 1.3 2.7 -1.2 -1.6 -0.7 -0.9 -1.4 -1.1 -0.8 -1.0
Miserableness 0.2 0.3 0.8 -0.2 0.2 0.3 -0.9 0.4 -0.2 0.7 0.9
Guilty feelings 0.5 0.8 3.2 0.3 1.8 0.2 0.2 1.1 0.9 0.5 0.8
Wears glasses or contact lenses 0.8 0.9 2.8 -0.5 0.0 0.1 -1.5 0.3 -1.7 -1.4 0.3
Ever taken oral contraceptive pill 1.7 1.9 6.7 0.2 -0.2 0.7 2.1 0.3 1.6 2.6 0.5
Hearing aid user 1.0 1.1 4.7 -0.4 0.4 0.2 -0.8 0.5 -1.7 -2.2 0.3
Mother’s age at death 0.4 0.5 1.1 -0.9 -0.2 0.3 -0.6 1.1 0.0 -0.8 1.0
Financial situation satisfaction 2.4 3.0 10.6 -0.8 -0.5 2.4 -3.2 0.5 -0.8 -1.6 1.9
Tinnitus: Yes, now most or all of the time 0.6 0.7 1.4 -0.6 -0.3 1.2 -1.2 0.6 -0.3 -0.9 0.8
Commuting to job workplace: Public transport 0.6 0.7 2.3 -0.4 -0.2 0.6 -1.5 -0.4 -1.3 -0.7 -0.6
Eye problems/disorders: Glaucoma 1.9 2.2 7.5 -1.0 -0.4 -2.7 0.9 -1.6 0.3 0.5 -2.3
Medication: Blood pressure 0.2 0.3 0.8 -0.2 0.4 -0.5 -0.4 -0.3 -0.5 -0.9 -0.8
Pain type(s) experienced in last month: Hip pain 0.4 0.6 1.7 0.7 0.7 0.6 -0.7 1.0 0.0 -0.1 1.3
Supplements: Fish oil (including cod liver oil) 0.8 1.1 2.0 0.4 -1.1 1.3 -1.4 0.0 -1.4 -1.2 0.3
High cholesterol (Self-reported) 0.3 0.5 1.3 0.4 0.4 -1.1 0.7 0.3 0.9 0.9 -0.3
Medication: Bendroflumethiazide 0.7 1.1 2.4 -0.8 0.5 -0.9 -0.6 -1.1 -1.2 -1.1 -1.5
Medication: Paracetamol 1.1 1.7 4.7 2.2 0.7 0.8 1.6 0.7 1.8 1.2 0.4
Medication: Lisinopril 0.3 0.4 1.6 -0.5 -1.3 -0.6 -0.8 -0.2 0.5 0.3 -0.0
Medication: Atorvastatin 0.6 0.7 2.6 0.9 0.4 -1.1 0.0 -0.9 -0.2 -0.2 -1.6
Illnesses of father: High blood pressure 0.5 0.6 1.7 -0.8 -0.5 -1.2 -1.3 -0.1 -0.3 0.9 0.2
Alcohol drinker status: Never 0.4 0.5 1.3 -0.1 -0.6 0.9 -1.2 0.1 -0.7 -1.1 0.0
Ever smoked 3.7 6.6 18.7 -1.2 -0.5 -3.7 1.4 -3.7 -1.1 -1.4 -4.3
Basal metabolic rate 0.9 4.9 14.4 1.3 1.6 -0.2 2.1 2.3 3.8 3.1 1.4
Leg fat percentage (left) 1.0 3.7 8.5 0.8 -0.1 -2.3 2.7 -0.1 2.4 2.9 -1.4
Arm fat-free mass (left) 0.7 3.4 11.4 1.0 1.1 -0.4 2.0 1.6 3.4 2.4 1.0
Number of operations (self-reported) 0.4 0.6 1.6 0.4 -1.3 -0.5 -1.3 -1.1 -0.1 0.2 -0.4
Average weekly beer plus cider intake 0.7 1.0 3.5 0.7 0.5 0.3 1.1 -0.1 1.5 1.9 -0.2
Irritability 0.4 0.7 2.2 0.0 -1.0 -0.3 0.8 -0.3 1.5 1.4 0.1
Risk taking 2.1 3.0 8.9 -1.2 -0.8 -3.0 0.5 -1.6 1.4 1.9 -2.1
Ever had prostate specific antigen (PSA) test 0.3 0.4 0.7 0.3 -0.7 0.7 0.1 0.8 0.3 -0.9 0.8
Fractured/broken bones in last 5 years 0.8 1.1 3.6 0.8 0.9 -1.1 1.9 -0.5 0.3 0.6 -1.3
Age started oral contraceptive pill 2.1 2.6 9.9 -0.1 -1.9 0.9 -2.2 -0.6 -1.0 -3.1 0.6
Diastolic blood pressure, automated reading 0.3 1.0 4.0 0.6 0.8 -0.9 2.0 0.3 1.0 1.2 -0.2
Ever depressed for a whole week 0.4 0.4 2.1 0.1 1.4 -1.0 0.3 -0.1 0.2 -0.2 -0.5
Unable to work because of sickness or disability 1.4 1.9 4.4 0.5 0.9 1.8 0.2 2.1 1.5 0.6 1.9
Commuting to job workplace: Cycle 0.4 0.5 1.5 -0.4 1.2 -1.2 -0.4 -0.3 -0.5 -0.4 -0.2
Myopia 1.0 1.5 3.6 -0.5 -1.2 -0.8 -1.9 -1.0 -1.9 -1.1 -0.3
Vascular/heart problems diagnosed by doctor 0.4 1.1 2.4 0.9 -1.0 1.4 -0.8 0.7 0.6 0.7 1.6
Cholesterol lowering medication 0.2 0.3 1.2 0.3 -0.0 -1.1 -0.3 -0.2 0.9 -0.1 -0.4
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 2.9 -1.0 -0.3 -0.2 -1.1 -0.7 -0.8 -1.7 -0.9
Pain experienced in last month 0.8 1.4 2.5 1.2 -0.2 1.3 0.6 1.6 1.0 1.2 1.5
Supplements: Calcium 1.2 1.3 3.5 0.9 0.4 1.9 -0.9 1.6 0.1 -0.6 1.6
Basal cell carcinoma (self-reported) 0.7 0.8 2.8 0.2 -0.1 -0.5 0.8 -0.1 1.7 1.5 -0.4
Heart attack/myocardial infarction (self-reported) 0.4 0.5 1.3 -0.4 1.0 -0.2 -0.8 0.1 -1.1 -1.1 -0.0
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.2 0.5 -0.0 -0.5 0.2 -0.3 0.0 0.4 -0.5
Heart disease (siblings) 1.6 2.0 5.8 -0.5 -0.2 -2.4 -0.1 -1.6 -1.6 -0.8 -2.0
Alcohol drinker status: Previous 1.4 1.6 3.3 1.5 1.8 0.1 0.6 1.6 1.4 0.9 1.3
Pack years of smoking 0.2 0.3 0.8 -0.2 0.9 0.8 0.4 -0.0 0.6 -0.8 -0.4
Impedance of whole body 0.5 2.5 6.2 -1.6 -0.5 1.5 -2.0 -0.2 -2.5 -2.1 0.7
Leg fat mass (left) 1.2 4.7 12.2 1.0 0.7 -1.9 2.9 0.9 3.3 3.5 -0.6
Arm predicted mass (left) 0.7 3.6 12.8 1.1 1.1 -0.4 2.0 1.7 3.6 2.4 1.1