TWAS hub - KIF20B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1310	0.0290	7.2e-16	0.161	0.163	0.171	0.169	0.167	3.4e-19	2.3e-19	2.3e-20	5.1e-20	6.8e-20
2	GTEx	Artery Tibial	0.0517	0.0233	7.3e-03	0.015	NA	0.022	NA	0.018	2.2e-02	NA	7.0e-03	NA	1.3e-02
3	GTEx	Nerve Tibial	0.0858	0.0362	1.7e-03	0.008	NA	0.028	NA	0.026	8.4e-02	NA	4.2e-03	NA	5.7e-03
4	GTEx	Testis	0.1250	0.0460	3.6e-04	0.102	NA	0.033	NA	0.094	3.0e-05	NA	1.3e-02	NA	5.9e-05
5	GTEx	Thyroid	0.0870	0.0360	2.0e-03	0.009	NA	0.007	NA	0.007	6.6e-02	NA	9.3e-02	NA	8.4e-02
6	ROSMAP	Brain Pre-frontal Cortex	0.0532	0.0203	5.1e-04	0.021	0.016	0.008	0.017	0.026	7.6e-04	3.3e-03	2.7e-02	2.8e-03	2.2e-04
7	TCGA	Colon Adenocarcinoma	0.1580	0.0760	1.5e-06	0.087	0.107	0.097	NA	0.093	9.4e-06	9.5e-07	3.3e-06	NA	5.1e-06
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0450	0.0241	1.3e-03	0.026	0.024	0.021	NA	0.025	5.3e-04	8.6e-04	1.9e-03	NA	7.4e-04
9	TCGA	Brain Lower Grade Glioma	0.0474	0.0318	8.8e-03	-0.002	0.008	0.012	NA	-0.002	6.2e-01	3.6e-02	1.5e-02	NA	5.6e-01
10	TCGA	Prostate Adenocarcinoma	0.0258	0.0197	6.6e-03	0.021	0.015	-0.001	NA	0.014	2.7e-03	1.0e-02	4.1e-01	NA	1.1e-02
11	TCGA	Thyroid Carcinoma	0.0500	0.0320	2.9e-03	0.017	0.027	0.027	NA	0.022	7.2e-03	1.1e-03	1.0e-03	NA	2.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Medication: Omeprazole (e.g. Zanprol)	5.7	7.0	13.3	2.5	3.3	1.9	2.4	1.3	2.0	3.5	3.3	1.2	2.5	3.6
Medication: Omeprazole	5.6	6.7	14.8	2.1	3.0	1.6	2.3	1.4	1.8	3.6	3.6	0.7	2.4	3.9
Lung cancer (father)	4.6	5.3	10.7	-2.1	-3.3	-0.8	-2.4	-2.6	-1.7	-2.4	-2.6	-0.1	-2.3	-3.1
Handedness (chirality/laterality): Left-handed	3.9	4.7	8.6	2.5	1.1	1.9	2.4	1.1	2.9	2.4	1.0	2.7	2.9	1.5
Serious illness, injury or assault of a close relative in last 2 years	3.8	4.4	9.8	-2.2	0.4	-2.7	-2.0	-0.6	-2.8	-2.7	-1.0	-3.1	-2.3	-0.5
Financial situation satisfaction	3.7	4.6	9.5	3.1	2.5	1.8	2.4	0.8	2.7	2.5	1.1	1.3	2.7	1.1
Mouth/teeth dental problems	3.6	5.6	9.9	2.9	2.5	2.2	2.9	2.3	3.1	2.1	0.6	-0.3	3.1	1.9
Mouth/teeth dental problems: Bleeding gums	3.4	4.4	7.9	-2.2	-1.2	-2.3	-2.1	-2.3	-2.2	-2.6	-2.0	-0.2	-1.9	-2.8
Breast Cancer	3.3	7.9	12.7	3.4	2.2	1.4	2.9	2.6	3.1	3.6	2.4	2.6	3.3	2.8
Commuting to job workplace: Public transport	3.3	3.9	9.5	-1.8	-0.8	-0.0	-2.3	-1.1	-1.6	-3.1	-2.7	-1.7	-2.1	-2.5
Bilateral oophorectomy (both ovaries removed)	3.2	3.6	13.8	2.0	3.7	1.7	2.2	2.2	1.0	1.2	0.6	0.1	2.1	1.6
Schizophrenia (2018)	3.0	6.3	12.6	3.1	3.2	1.8	3.4	2.4	3.5	1.8	-0.4	0.9	3.5	0.6
Wears glasses or contact lenses	2.9	3.4	6.1	-1.9	-1.6	-0.1	-1.8	-1.7	-2.0	-2.5	-2.0	-1.5	-2.3	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.7	3.1	6.7	2.0	1.4	1.1	1.7	1.2	2.1	2.1	1.3	2.6	2.2	0.8
Heart disease (siblings)	2.7	3.3	6.7	-2.4	-0.2	-1.6	-2.2	-1.4	-1.5	-2.6	-1.5	-1.7	-2.2	-1.4
Pulse wave Arterial Stiffness index	2.6	3.1	5.6	-1.8	-0.8	-1.1	-1.6	-2.1	-2.0	-2.2	-1.6	-2.4	-2.0	-1.1
Gout (self-reported)	2.6	3.6	6.4	-1.9	-1.7	-0.2	-2.0	-2.2	-1.7	-2.5	-2.1	-2.1	-1.8	-1.8
Blood Red Count	2.5	24.1	58.1	-4.6	-6.6	-0.6	-5.9	-3.3	-1.9	-5.8	-5.7	-0.5	-5.2	-7.6
Past tobacco smoking	2.5	4.5	11.5	2.8	1.9	3.4	3.1	-0.7	1.5	1.8	0.3	0.0	2.8	2.0
Happiness	2.5	3.0	8.0	2.3	2.8	1.8	2.0	0.5	2.2	1.3	0.1	-0.1	2.1	0.9
Smoking status: Previous	2.5	3.8	9.7	-2.5	-2.1	-3.1	-2.8	0.1	-1.6	-1.5	-0.2	0.3	-2.4	-1.7
Ever unenthusiastic/disinterested for a whole week	2.4	2.9	6.8	2.1	1.9	2.6	2.1	-0.9	1.8	0.2	-2.0	0.7	1.9	-0.7
Medication: Allopurinol	2.4	3.1	5.7	-1.9	-1.6	0.2	-2.1	-1.7	-1.7	-2.4	-1.6	-1.5	-2.1	-1.8
Ever had hysterectomy (womb removed)	2.3	2.6	6.4	1.5	1.5	1.4	1.9	1.7	0.7	1.7	1.7	-0.7	1.6	2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.3	2.7	5.7	1.6	2.4	2.3	1.8	0.8	1.3	1.8	1.0	0.9	1.9	1.2
Ever had prostate specific antigen (PSA) test	2.3	2.6	12.6	1.0	1.5	0.5	1.4	3.5	1.4	1.4	1.4	-0.4	1.5	1.6
Bipolar Disorder or Schizophrenia	2.2	5.4	11.0	3.0	2.8	2.2	3.3	2.3	2.9	1.3	-0.7	0.2	3.3	0.8
Pulse wave peak to peak time	2.2	2.6	4.8	1.6	0.7	0.7	1.3	2.0	1.7	2.0	1.6	2.2	1.8	1.1
Ever taken oral contraceptive pill	2.2	2.5	6.4	-1.4	0.2	-0.9	-1.0	-0.4	-2.2	-2.2	-1.9	-2.5	-1.6	-0.8
Bipolar Disorder (2011)	2.1	2.0	7.4	1.0	1.5	-0.4	1.1	1.0	0.2	1.5	2.5	-0.3	0.9	2.7
Schizophrenia (2014)	2.1	4.5	9.3	2.4	3.0	1.3	2.8	2.2	2.8	1.4	-0.3	0.9	3.1	0.6
Serious illness, injury or assault to yourself	2.1	2.6	6.4	1.7	2.2	-0.4	1.9	-0.1	0.2	2.1	1.9	-0.2	1.4	2.5
Qualifications: O levels/GCSEs or equivalent	2.1	3.3	11.5	-0.8	-1.4	0.8	-0.9	-2.5	-0.1	-2.3	-3.4	-0.3	-0.5	-3.1
Blood clot in the leg (DVT)	1.9	2.4	5.8	1.1	1.2	1.3	1.2	1.1	1.4	2.1	2.4	0.6	1.6	2.1
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	5.1	2.1	2.2	1.7	1.9	0.0	1.7	0.8	-0.8	-0.5	2.3	0.4
Knee pain experienced in last month	1.9	3.0	7.8	1.2	1.7	0.7	1.1	1.7	0.7	2.5	2.8	1.6	1.0	2.3
HbA1C	1.8	2.0	6.0	1.6	1.4	1.1	2.5	-0.1	0.8	1.5	0.8	1.1	1.6	1.6
Blood White Count	1.8	13.6	27.9	-4.7	-4.5	-3.9	-5.0	-1.7	-4.3	-3.2	-0.7	-1.4	-5.3	-2.2
Relative age voice broke	1.8	2.8	7.4	-1.7	-1.8	-1.6	-1.9	0.8	-1.0	0.6	2.5	2.7	-1.7	0.1
Medication: Ventolin 100micrograms inhaler	1.8	2.3	6.5	1.1	2.5	-0.3	1.4	2.5	1.0	1.2	1.2	0.5	1.4	1.7
Overall health rating	1.8	3.9	7.3	2.2	2.7	0.2	1.7	1.7	1.0	2.5	2.6	0.8	1.7	2.7
Eye problems/disorders: Glaucoma	1.8	2.2	6.7	0.9	1.2	-0.3	0.7	1.1	0.7	1.9	2.4	2.6	0.6	1.8
Coronary Artery Disease (CAD)	1.7	2.1	6.5	-1.5	-2.0	-2.6	-1.6	1.2	-0.8	-0.6	-0.0	1.4	-1.4	-1.1
Ever depressed for a whole week	1.7	2.0	4.1	1.7	2.0	1.5	1.7	0.7	1.9	0.9	-0.6	1.4	1.9	-0.1
Ovarian Cancer	1.6	2.1	9.2	0.2	0.2	-0.3	0.8	1.1	-0.8	1.9	2.8	0.4	0.3	3.0
Illnesses of siblings	1.6	2.2	5.5	2.0	-0.0	1.9	1.4	-0.3	2.3	1.2	-0.3	1.6	2.1	-0.8
Glaucoma (self-reported)	1.6	1.9	4.5	0.9	1.7	-0.4	0.9	1.3	1.0	1.5	2.0	2.1	0.9	1.5
Leg fat percentage (left)	1.6	5.6	14.2	-2.9	-0.7	-2.7	-2.6	2.3	-3.8	-1.1	2.2	-1.8	-3.0	1.3
Deep venous thrombosis (DVT) (self-reported)	1.6	2.1	5.1	1.0	1.0	1.4	1.1	1.0	1.3	2.0	2.3	0.5	1.5	2.0
Alzheimer’s Disease (in father)	1.5	1.6	6.2	1.2	0.8	1.3	0.6	2.5	2.0	1.0	0.5	0.7	1.0	0.6
Medication for hormone replacement therapy	1.5	1.6	4.5	2.0	1.9	0.2	2.1	-0.3	0.8	0.5	-0.7	1.0	1.9	0.5
Maternal smoking around birth	1.5	2.2	4.4	-1.9	0.6	-2.1	-1.9	-0.0	-2.0	-0.9	1.2	-1.4	-1.8	0.8
Leg fat percentage (right)	1.5	5.5	12.6	-2.8	-0.8	-2.7	-2.6	2.2	-3.5	-1.1	2.2	-1.8	-3.0	1.2
Number of operations (self-reported)	1.5	2.3	4.9	2.1	2.2	1.3	1.9	0.3	1.8	1.4	-0.0	0.9	2.1	0.4
Chronotype (morning person)	1.4	3.2	6.9	1.7	1.9	2.6	1.8	2.1	1.5	1.9	1.6	0.5	1.4	1.9
Tinnitus: Yes, but not now, but have in the past	1.4	1.4	3.7	1.9	1.2	0.1	1.8	1.3	1.3	0.6	-0.8	0.4	1.7	0.2
Length of working week for main job	1.4	1.5	4.5	-1.7	-1.4	-2.1	-1.7	-0.1	-0.8	-0.8	0.3	0.0	-1.5	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.1	4.2	1.8	1.7	1.7	1.9	0.0	2.0	1.4	-0.1	1.2	1.8	0.4
Eye problems/disorders: None of the above	1.4	1.6	4.4	-1.0	-1.3	-0.1	-1.2	-0.1	-0.8	-1.7	-1.8	-1.2	-1.1	-2.1
Pack years of smoking	1.4	2.0	5.6	0.3	0.9	-1.5	0.8	2.4	-0.1	1.6	2.4	0.1	0.4	2.1
Medication: Lansoprazole	1.3	1.5	3.1	1.7	0.5	0.0	1.5	-0.5	0.7	1.8	1.3	1.2	1.2	1.5
Birth weight	1.3	2.7	11.0	0.9	0.7	1.3	1.0	2.3	2.3	1.4	0.5	3.3	1.5	-0.2
Heart disease (mother)	1.3	1.6	4.4	-1.5	0.6	-2.1	-1.0	-1.6	-0.9	-1.3	-0.6	-1.6	-1.2	-0.2
Mouth/teeth dental problems: Mouth ulcers	1.3	2.0	9.8	-0.5	-1.2	0.1	-1.1	-3.1	-1.2	-1.3	-1.6	-0.4	-1.1	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	6.9	-1.3	-2.3	0.6	-0.9	-1.7	-0.9	-2.3	-2.6	-1.1	-1.1	-1.8
Ever smoked	1.3	2.3	5.1	-1.6	-1.4	-1.8	-2.2	0.5	-0.6	-1.4	-0.9	0.2	-1.9	-2.2
Pain all over the body in last month	1.2	1.3	4.2	1.0	1.3	0.5	1.0	0.7	1.0	1.1	1.0	2.1	1.3	0.7
Medication: Simvastatin	1.2	1.8	7.8	1.0	0.5	1.1	0.9	2.8	0.9	1.5	1.7	0.1	0.5	1.6
Qualifications: A levels/AS levels or equivalent	1.2	2.7	13.9	0.6	1.1	1.3	0.6	-1.6	0.6	-1.8	-3.7	-0.5	1.0	-2.3
Breastfed as a baby	1.2	1.5	2.5	1.4	1.2	0.5	1.3	1.2	1.6	1.4	0.7	1.5	1.4	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.5	8.3	-0.5	-1.2	-1.1	-0.6	-2.9	-1.0	-0.8	-1.1	-0.4	-0.6	-1.0
Vitamin and mineral supplements	1.1	1.5	6.2	-0.7	-0.8	-1.3	-0.2	1.7	-0.1	1.1	2.5	0.2	-0.7	1.7
Ever highly irritable/argumentative for 2 days	1.1	1.3	5.2	0.0	0.6	-1.3	-0.1	0.4	-1.4	0.9	2.3	-0.4	-0.5	2.0
Leg fat mass (right)	1.1	4.4	10.8	-1.8	0.3	-2.4	-1.5	2.8	-2.8	0.3	3.3	-0.8	-1.9	2.4
Breast cancer (self-reported)	1.1	1.3	6.7	0.5	-0.1	1.0	0.1	-0.7	0.8	-1.2	-2.6	-0.2	0.0	-2.1
Leg fat mass (left)	1.1	4.4	10.4	-1.9	0.3	-2.4	-1.5	2.8	-2.9	0.2	3.2	-0.7	-2.0	2.3
Hypothyroidism (self reported)	1.0	2.3	4.8	-2.1	-0.4	-2.2	-2.1	-0.6	-2.2	-1.3	0.4	0.2	-2.1	-0.3
Trunk fat mass	1.0	4.1	11.4	-1.9	0.2	-1.9	-1.6	3.1	-2.5	0.5	3.4	-0.2	-1.9	2.1
Qualifications: None of the above	1.0	2.0	4.3	-1.3	-1.2	-2.0	-1.1	0.7	-1.8	0.5	2.1	-0.6	-2.0	1.2
Medication: Ramipril	1.0	1.3	4.1	-1.6	-0.5	-1.4	-2.0	1.0	-0.5	-0.7	0.9	0.7	-1.5	-0.6
Asthma	1.0	2.0	7.7	1.6	2.8	0.4	1.2	1.0	1.0	1.6	1.4	1.1	1.1	1.1
Medication: Paracetamol	1.0	1.6	3.8	-1.1	-0.7	-1.3	-1.4	-2.0	-1.9	-0.7	-0.3	-0.7	-1.5	-1.1
Medication: Amlodipine	1.0	1.3	2.6	1.0	1.3	1.0	0.8	1.0	0.9	1.6	1.6	-0.5	0.8	1.6
Body fat percentage	1.0	4.1	8.4	-2.2	-0.2	-2.2	-1.8	2.6	-2.9	-0.2	2.7	-1.1	-2.2	1.9
Number of full brothers	1.0	1.2	2.5	-0.9	-1.6	-1.3	-1.0	-1.4	-1.5	-1.0	-0.8	-0.5	-1.1	-0.5
Age at first live birth	1.0	1.8	5.4	-0.8	-0.7	0.3	-1.1	-1.5	-0.7	-1.7	-2.3	-0.9	-0.9	-2.1
Whole body fat mass	1.0	4.0	11.2	-1.8	0.4	-1.8	-1.4	3.1	-2.5	0.5	3.3	-0.4	-1.7	2.3
Average weekly red wine intake	1.0	1.4	3.3	1.3	1.5	1.1	1.0	1.1	1.8	0.1	-1.1	1.1	1.4	-0.6
Myopia	1.0	1.5	5.8	-1.5	1.1	-0.1	-1.1	-0.7	-0.6	-1.6	-1.1	-2.4	-1.0	-0.5
Alcohol drinker status: Previous	1.0	1.1	4.0	-1.4	-0.2	-2.0	-1.1	0.4	-1.0	-0.4	0.6	1.1	-1.4	0.0
Intelligence (Savage-Jansen 2018)	0.9	2.7	7.7	1.6	2.8	2.7	1.4	-0.3	1.7	0.0	-1.6	0.5	1.7	-1.0
Mean Putamen Volume	0.9	1.0	3.1	1.2	1.4	1.8	1.2	0.4	0.6	0.6	-0.0	0.6	1.2	0.8
Lupus	0.9	1.4	5.0	0.2	-0.2	1.1	-0.3	-1.7	0.0	-1.4	-2.2	-1.0	-0.3	-1.7
Supplements: Zinc	0.9	1.0	4.0	0.4	1.4	-1.5	0.4	0.5	0.5	-0.2	-0.8	2.0	0.4	-0.7
Pack years adult smoking proportion	0.9	1.4	3.5	0.3	1.0	-1.4	0.9	1.9	0.1	1.4	1.7	0.1	0.6	1.7
Trunk fat percentage	0.9	3.8	7.2	-2.2	-0.1	-2.0	-1.8	2.6	-2.7	-0.1	2.7	-0.9	-2.1	1.7
Taking other prescription medications	0.9	1.4	2.7	1.0	1.6	-0.0	1.1	0.6	0.2	1.5	1.6	1.6	0.8	1.3
Alcohol intake versus 10 years previously	0.9	1.3	2.3	1.5	1.4	0.1	1.5	1.0	0.4	1.4	1.1	0.0	1.1	1.5
Exposure to tobacco smoke at home	0.9	1.0	3.1	0.7	-0.0	1.4	0.4	0.9	0.7	1.5	1.8	1.0	0.5	0.8
Wheeze or whistling in the chest in last year	0.9	1.7	15.5	0.8	3.9	-0.0	0.5	0.1	0.7	0.6	0.4	-0.3	0.8	0.5
Mouth/teeth dental problems: Loose teeth	0.9	1.0	3.5	-1.1	0.4	-1.9	-1.0	0.3	-1.5	-0.5	1.0	-0.4	-1.3	0.6
Commuting to job workplace: Car/motor vehicle	0.9	1.0	2.2	0.9	-0.2	-0.3	1.1	1.0	0.6	1.4	1.5	1.1	0.5	1.4
Medication: Gliclazide	0.9	1.0	3.5	0.6	1.7	0.0	0.9	0.5	0.2	0.8	1.4	-0.3	0.8	1.9
Average weekly champagne plus white wine intake	0.9	1.2	2.0	-1.2	-1.1	-0.2	-1.2	0.4	-0.5	-1.3	-1.4	-1.4	-1.1	-1.3
Arm predicted mass (left)	0.9	4.5	18.1	0.2	1.1	-0.6	0.3	3.0	-0.5	2.5	4.3	2.2	0.3	3.1
Lung FEV1/FVC ratio	0.8	4.2	9.3	-1.8	-1.5	0.1	-1.5	-2.9	-1.6	-2.6	-3.0	-1.7	-1.4	-2.6
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	3.9	-0.2	1.4	-0.6	-0.3	-2.0	-1.0	-0.7	-1.2	-0.7	-0.1	-1.5
Diabetes (father)	0.8	0.9	3.0	1.2	0.1	0.2	0.7	1.6	0.8	0.8	0.6	1.7	1.1	0.1
Medication: Atenolol	0.8	1.0	2.5	-1.5	-0.6	-1.2	-1.6	-0.6	-1.0	-0.9	0.2	-0.3	-1.4	-0.7
Impedance of leg (left)	0.8	3.7	6.4	-2.5	-1.8	-1.4	-2.5	-1.3	-1.6	-2.3	-1.6	-1.0	-2.3	-2.2
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	4.9	-1.6	-1.3	-2.2	-1.7	0.7	-1.6	-1.3	-0.1	-0.4	-1.8	-0.8
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	2.5	-1.2	-0.3	0.1	-0.9	-1.6	-0.2	-1.2	-1.5	0.1	-0.9	-1.6
Weight	0.8	4.0	15.7	-0.8	0.9	-1.2	-0.5	3.2	-1.7	1.5	4.0	0.9	-0.8	2.8
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.1	5.3	0.5	-0.1	0.7	-0.3	-0.9	0.6	-0.5	-1.8	1.1	0.2	-2.3
Arm fat mass (right)	0.8	3.3	12.1	-0.9	0.8	-1.5	-0.6	2.5	-2.0	1.1	3.5	-0.1	-1.1	2.7
Loud music exposure frequency	0.8	0.9	2.5	0.3	0.2	0.8	0.5	1.6	0.9	0.8	1.5	0.5	0.6	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.9	0.8	0.7	1.7	0.9	0.2	1.0	-0.2	-1.5	-0.2	1.0	-1.0
Qualifications: College or University degree	0.8	2.5	5.1	1.6	2.2	1.9	1.7	-0.3	1.9	0.0	-1.8	-0.6	2.2	-0.8
Illnesses of father: Heart disease	0.8	1.1	2.9	-1.5	-0.8	-0.8	-1.6	-0.2	-0.6	-1.2	-0.5	-0.7	-1.7	-1.0
Long-standing illness, disability or infirmity	0.8	1.2	5.1	1.2	2.3	0.1	1.0	0.5	0.1	1.0	1.0	0.4	1.0	1.3
Smoking status: Current	0.8	1.3	2.4	0.7	1.5	0.4	0.9	1.4	1.1	1.4	1.5	0.6	1.1	1.3
Arm fat mass (left)	0.8	3.4	12.7	-0.8	0.6	-1.4	-0.5	2.8	-1.9	1.3	3.6	0.1	-0.9	2.8
Medication: Paracetamol	0.8	1.2	3.2	-0.7	-0.6	-1.0	-1.1	-1.8	-1.6	-0.7	-0.7	-1.1	-1.2	-1.0
Medication: Lisinopril	0.8	1.1	4.6	-0.2	0.3	-1.1	0.1	2.1	-0.0	0.6	1.6	-0.6	0.1	1.5
Arm fat-free mass (left)	0.8	4.2	17.2	0.0	1.0	-0.6	0.2	3.0	-0.6	2.4	4.2	1.9	0.2	3.0
Irritability	0.8	1.3	3.1	-1.5	-1.2	-0.8	-1.8	-0.5	-1.3	-1.2	0.5	-0.4	-1.8	-0.3
Heart attack/myocardial infarction (self-reported)	0.8	1.1	3.1	-1.4	-0.1	-1.0	-1.0	-0.4	-1.8	-0.7	0.9	-1.1	-1.3	0.7
Age at First Birth	0.7	1.0	2.3	-0.6	-0.4	0.2	-1.0	-1.2	-0.8	-1.3	-1.1	-1.5	-0.5	-1.3
Type 2 Diabetes (T2D) (2012)	0.7	0.8	3.4	-0.9	-0.0	-0.6	-0.7	0.1	-1.0	0.3	1.8	1.4	-0.6	0.7
Systolic Blood Pressure	0.7	3.3	14.0	0.1	1.3	-1.6	0.2	2.0	0.3	1.6	3.7	0.6	-0.1	3.4
Sensitivity / hurt feelings	0.7	1.2	5.0	-0.7	-1.1	-0.0	-0.3	0.8	-1.0	1.1	2.2	0.5	-0.5	1.8
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.4	-0.2	0.8	-1.4	-0.3	0.9	-1.0	0.1	1.5	0.8	-0.6	1.3
Systolic blood pressure, automated reading	0.7	2.1	8.9	0.0	0.9	-1.3	0.0	1.9	0.7	1.3	3.0	1.1	0.0	2.1
Diabetes (mother)	0.7	0.9	3.5	-0.4	-0.8	-0.3	-0.1	0.7	-0.2	1.2	1.9	-0.1	-0.1	1.8
Impedance of leg (right)	0.7	3.5	5.9	-2.2	-1.9	-1.3	-2.4	-1.4	-1.1	-2.2	-1.7	-1.1	-2.2	-2.3
Current tobacco smoking	0.7	1.2	2.4	0.8	1.6	0.5	1.0	0.8	1.1	1.4	1.3	0.5	1.2	1.3
Multivitamins +/- minerals	0.7	0.9	3.5	0.3	-0.2	0.9	-0.0	-1.3	-0.1	-0.8	-1.9	0.8	0.2	-1.5
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	2.5	1.1	1.5	0.1	0.6	-1.0	1.0	0.3	-0.6	1.6	0.8	-0.6
Body mass index (BMI)	0.7	3.1	9.9	-1.1	0.4	-1.8	-0.7	2.4	-2.3	0.7	3.1	-0.2	-1.2	2.5
Diabetes (self-reported)	0.7	1.1	3.6	0.5	1.3	0.1	0.8	1.5	0.4	0.6	0.9	-1.4	0.6	1.9
Trunk fat-free mass	0.7	4.1	14.2	0.7	1.0	0.3	0.8	2.8	0.3	2.7	3.8	2.2	0.8	2.8
Worrier / anxious feelings	0.7	1.3	4.6	0.7	-0.7	0.5	0.2	1.2	0.5	1.5	2.1	1.4	0.2	1.6
Mouth/teeth dental problems: Dentures	0.7	1.2	3.1	-1.4	-1.6	-0.9	-1.6	0.4	-0.9	-0.1	1.1	0.2	-1.8	-0.2
Trunk predicted mass	0.7	4.0	14.0	0.7	1.0	0.2	0.7	2.7	0.2	2.6	3.7	2.3	0.7	2.8
Headache pain in last month	0.7	1.2	1.9	-1.2	-0.6	-1.3	-1.2	-1.4	-1.3	-0.9	-0.5	-1.1	-1.3	-0.9
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	6.3	0.0	-0.1	-0.6	0.2	-2.5	-0.4	-0.9	-1.4	1.0	0.2	-1.2
Chronic bronchitis/emphysema (mother)	0.7	0.9	2.8	-1.1	-0.6	-1.7	-1.1	-0.4	-1.0	-0.0	1.2	-0.2	-1.0	0.5
Arm fat-free mass (right)	0.7	3.6	14.4	-0.4	0.3	-1.4	-0.4	2.9	-1.0	1.8	3.8	2.0	-0.4	2.5
Exposure to tobacco smoke outside home	0.7	0.9	2.9	1.2	1.7	-0.1	1.0	-0.5	1.4	0.5	-0.6	1.0	1.1	-0.0
Worry too long after embarrassment	0.7	1.2	2.5	-1.4	-1.6	-1.3	-1.3	0.2	-1.3	0.1	1.2	0.9	-1.2	0.4
Arm predicted mass (right)	0.7	3.6	15.1	-0.7	0.2	-1.4	-0.6	2.7	-1.1	1.8	3.9	1.9	-0.5	2.5
Pulse rate, automated reading	0.7	2.1	4.6	-1.5	-1.5	-1.5	-1.9	-1.6	-2.0	-0.7	0.4	-1.1	-2.1	-0.0
Chest pain or discomfort	0.7	1.0	5.6	0.4	2.4	0.4	0.1	-0.9	1.0	0.7	0.6	1.1	0.8	0.1
Whole body fat-free mass	0.7	3.8	14.0	0.5	1.1	-0.2	0.7	2.8	-0.0	2.4	3.7	1.8	0.6	2.9
Qualifications: nursing, teaching	0.7	1.1	3.6	0.5	1.9	0.9	1.0	-0.2	0.9	-0.8	-1.6	-0.3	1.3	-0.6
Osteoarthritis (self-reported)	0.7	0.9	3.6	1.1	1.9	1.3	0.8	0.9	0.9	0.6	0.1	-0.2	0.9	0.4
Whole body water mass	0.7	4.0	14.7	0.5	1.2	-0.2	0.7	2.8	-0.0	2.5	3.8	2.0	0.6	2.9
Miserableness	0.7	1.2	2.2	-1.1	-1.3	-0.7	-1.0	-0.7	-0.9	-1.3	-1.2	-1.3	-1.5	-0.9
Medication: Bendroflumethiazide	0.7	1.1	4.9	-0.1	-0.6	-0.3	-0.3	1.4	-0.6	0.7	2.2	-0.4	-0.5	2.0
Basal metabolic rate	0.7	3.7	14.7	0.1	1.1	-0.5	0.3	2.9	-0.6	2.2	3.8	1.6	0.2	2.9
Diastolic blood pressure, automated reading	0.7	2.2	5.5	-2.1	-0.3	-2.3	-1.9	0.4	-1.7	-1.2	0.7	-0.1	-2.3	-0.3
Commuting to job workplace: Cycle	0.7	0.8	3.7	-0.5	-0.3	0.6	-0.5	-0.8	-0.1	-1.2	-1.9	0.2	-0.2	-1.5
Depression (Nagel 2018)	0.6	0.9	2.5	0.5	1.6	-1.0	0.4	1.5	-0.5	0.3	0.9	-0.5	0.3	1.5
Major Depression (MDD)	0.6	0.7	4.0	0.9	2.0	0.3	1.2	0.1	-0.1	0.3	-0.3	-0.1	1.0	0.3
Reaction Time	0.6	1.1	4.3	-1.0	-0.9	-0.1	-1.4	-0.7	0.0	-1.2	-1.2	-0.0	-1.1	-2.1
Lung FVC	0.6	3.1	8.5	2.5	0.8	2.0	2.9	-0.1	1.3	1.6	0.3	-0.6	2.3	2.1
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.8	0.7	1.7	-0.2	0.6	1.0	-0.2	0.6	0.7	-1.0	0.5	1.4
Medication: Metformin	0.6	0.9	2.8	-0.4	0.2	-1.2	-0.0	1.3	-0.7	0.5	1.2	-0.9	-0.4	1.7
Leg fat-free mass (left)	0.6	2.9	10.7	0.3	1.3	-0.6	0.6	2.6	-0.3	1.9	3.3	1.0	0.4	2.7
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	2.7	-1.2	-1.2	-1.6	-1.2	1.1	-1.6	-0.3	1.1	-0.2	-1.5	0.5
Leg predicted mass (left)	0.6	2.9	10.7	0.3	1.2	-0.6	0.6	2.6	-0.3	1.9	3.3	1.1	0.4	2.7
Waist circumference	0.6	2.3	8.7	-0.8	0.7	-1.2	-0.6	2.2	-1.4	0.9	3.0	0.5	-0.8	2.2
Arm fat percentage (right)	0.6	2.2	6.6	-0.8	0.6	-1.1	-0.4	2.2	-1.8	0.6	2.6	-1.0	-1.0	2.3
Hip circumference	0.6	2.5	8.1	-1.2	0.9	-1.1	-1.0	2.5	-1.8	0.8	2.8	-0.1	-1.2	1.9
Hair/balding pattern: Pattern 3	0.6	0.9	5.0	0.0	-0.5	1.6	0.2	0.8	-0.3	-0.3	-0.9	-2.2	-0.1	0.2
Medication: Cholesterol lowering	0.6	1.0	4.1	0.6	0.2	1.4	0.2	2.0	1.0	1.1	1.0	-0.4	0.4	0.9
Hair/balding pattern: Pattern 4	0.6	1.3	10.5	-0.6	-0.5	-3.2	-1.2	-0.4	-0.5	-0.8	-0.2	-0.0	-0.9	-0.6
Medication: Blood pressure	0.6	1.0	6.9	-0.4	-0.1	-0.1	-0.5	2.6	0.3	0.5	1.2	-1.0	-0.5	0.8
Mean time to correctly identify matches	0.6	1.2	3.3	-1.3	-1.2	0.1	-1.7	0.3	-0.0	-1.1	-0.8	-0.1	-1.4	-1.8
Family relationship satisfaction	0.6	0.8	6.4	0.2	2.5	-0.6	0.1	1.0	0.6	0.1	-0.1	-0.2	0.3	0.1
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	3.0	0.2	-0.9	0.7	-0.3	0.2	1.0	-0.4	-1.3	0.9	0.1	-1.7
Leg fat-free mass (right)	0.6	3.1	10.6	0.4	1.4	-0.4	0.7	2.7	-0.2	2.0	3.2	1.3	0.6	2.7
Arm fat percentage (left)	0.6	2.4	5.8	-1.2	0.2	-1.5	-0.8	2.2	-2.2	0.3	2.4	-0.9	-1.3	2.1
Asthma (self-reported)	0.6	1.2	5.2	1.3	2.3	0.3	0.7	0.6	0.7	1.2	1.2	0.9	0.7	0.8
Medication: Aspirin	0.6	0.7	2.4	-0.5	0.2	-1.3	-0.8	-1.6	-0.9	-0.7	-0.6	-0.5	-0.8	-0.7
Illnesses of father: None of the above (group 1)	0.6	0.7	1.7	0.8	1.3	1.0	1.0	-1.3	0.2	0.1	-0.5	-0.6	1.0	0.3
Leg predicted mass (right)	0.6	3.2	10.7	0.5	1.5	-0.4	0.8	2.6	-0.2	2.1	3.3	1.3	0.7	2.7
High cholesterol (Self-reported)	0.6	1.0	3.4	-0.8	-1.1	-0.1	-1.2	1.9	-0.7	0.2	1.3	0.6	-1.4	0.4
Unable to work because of sickness or disability	0.6	0.8	1.9	0.8	1.1	0.2	0.3	0.3	0.1	1.2	1.4	1.2	0.3	1.1
Alzheimer’s Disease (including proxy)	0.5	0.7	2.2	0.7	-0.0	0.8	0.6	0.8	1.2	1.0	0.5	1.5	0.7	0.6
BMI	0.5	2.7	9.5	-1.0	0.3	-1.5	-0.9	2.5	-1.7	0.7	3.1	0.6	-1.2	2.2
Relative age of first facial hair	0.5	1.1	3.1	-1.0	-1.4	-0.9	-1.2	-0.1	-0.9	0.4	1.2	1.8	-1.1	0.0
Severe depression (siblings)	0.5	0.5	1.6	-0.8	-0.3	-0.5	-1.0	0.3	0.0	0.1	1.0	1.3	-1.0	-0.1
Chronic bronchitis/emphysema (father)	0.5	0.6	4.3	0.6	2.1	-0.9	0.3	-0.4	0.2	0.2	-0.2	0.3	0.5	-0.0
Number of incorrect matches in round	0.5	0.8	4.5	-0.4	-1.1	0.2	-1.1	-0.1	0.6	-0.0	0.1	2.1	-0.5	-1.2
Heart attack	0.5	0.7	1.6	-1.1	0.0	-0.7	-0.8	-0.3	-1.3	-0.4	1.1	-0.6	-1.0	0.8
Depression (self-reported)	0.5	0.6	3.3	1.1	0.7	1.8	0.5	-0.2	0.6	0.4	-0.4	-0.1	0.8	-0.4
Illnesses of mother	0.5	0.6	2.6	0.3	-0.2	1.2	-0.3	1.1	0.8	0.0	-0.7	0.7	0.1	-1.6
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.4	-1.2	-0.1	-1.3	-1.4	-0.4	-1.6	-0.8	0.2	0.5	-1.3	-0.3
High blood pressure (siblings)	0.5	0.7	2.3	-0.2	0.8	-0.6	0.3	1.3	-1.1	0.2	0.8	-1.1	-0.5	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.0	0.4	0.8	0.7	0.3	-1.2	0.1	-0.2	-1.0	1.4	0.5	-1.1
Number of children fathered	0.5	0.6	2.1	-0.2	-1.4	1.5	-0.2	1.0	0.2	0.5	1.1	0.4	-0.0	-0.1
Health satisfaction	0.5	0.7	1.9	1.2	0.9	1.4	0.8	0.1	0.4	0.8	0.2	-0.3	0.9	0.8
Medication: Ibuprofen	0.5	0.6	3.1	0.3	-1.0	0.3	-0.6	-0.4	0.3	-0.3	-1.1	0.6	-0.2	-1.8
Number of full sisters	0.5	0.6	1.7	-0.4	0.3	-0.8	0.0	0.2	-1.3	0.1	1.1	-0.9	-0.4	1.2
Supplements: Vitamin C	0.5	0.6	1.7	0.1	0.6	0.5	-0.4	-1.3	0.5	-0.8	-1.2	-0.5	0.2	-1.2
Diabetes diagnosed by doctor	0.5	0.8	2.7	-0.5	0.9	-0.8	-0.2	0.6	-0.8	0.0	0.9	-1.6	-0.5	1.4
Friendships satisfaction	0.5	0.6	2.2	1.0	1.5	0.3	0.8	0.4	1.1	0.8	0.1	-0.0	1.0	0.3
Mineral and other dietary supplements	0.5	0.7	3.2	-1.2	-0.3	-1.8	-0.7	-0.4	-0.4	-0.1	1.0	-0.3	-0.9	0.5
Illnesses of father: High blood pressure	0.5	0.7	2.7	-0.2	0.1	-0.9	-0.3	1.6	-0.1	0.2	1.4	1.1	-0.6	0.5
Basal cell carcinoma (self-reported)	0.5	0.6	1.4	-0.8	-1.2	-0.6	-0.9	-0.6	-0.7	-0.7	-0.3	-0.2	-1.2	-0.9
Bipolar Disorder (2018)	0.4	0.6	1.6	1.0	0.5	1.3	1.1	0.7	0.3	-0.1	-0.6	-0.9	0.8	0.4
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.1	0.6	1.5	1.2	0.4	-0.5	1.2	-0.4	-1.2	0.8	0.9	-1.1
Body Mass Index (BMI) (2010)	0.4	0.5	1.5	-0.8	0.1	-1.2	-0.3	-0.0	-1.0	-0.3	0.4	-1.2	-0.5	0.8
LDL Cholesterol	0.4	0.7	3.8	0.2	1.0	-0.5	0.5	-0.1	0.1	-0.7	-2.0	-0.7	0.5	-1.1
Rheumatoid Arthritis	0.4	0.5	1.7	0.1	-1.3	-0.0	-0.1	1.3	-0.3	0.6	0.9	-0.4	-0.3	0.8
Cardiovascular Disease	0.4	1.2	2.9	-1.2	-1.1	-0.5	-1.3	1.3	-1.1	-0.1	1.5	-0.1	-1.7	0.7
Neuroticism	0.4	0.9	3.6	0.0	-1.5	0.2	-0.5	0.7	0.3	1.1	1.9	1.3	-0.7	0.6
Number of treatments/medications taken	0.4	0.8	2.5	1.1	1.6	1.1	0.7	-0.0	0.8	1.0	0.6	0.1	0.8	0.7
Hearing difficulty/problems: Yes	0.4	0.6	1.9	-1.0	-0.3	-0.8	-1.0	-0.0	-1.3	-0.8	-0.0	-0.3	-1.4	-0.1
Fed-up feelings	0.4	0.8	2.2	1.5	0.9	1.1	0.9	0.7	1.3	0.5	-0.6	-0.5	0.9	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	2.0	-0.5	-0.0	-1.3	-0.6	-0.1	-1.4	-0.5	0.1	-1.0	-0.7	0.3
Supplements: Glucosamine	0.4	0.5	2.1	0.1	-0.1	0.5	-0.6	0.0	-0.7	-0.9	-1.4	-0.1	-0.4	-1.2
High blood pressure (mother)	0.4	0.6	2.8	0.1	0.3	-0.2	0.3	-0.6	-0.6	0.6	1.4	-0.6	0.1	1.7
Alcohol usually taken with meals	0.4	0.7	2.0	-0.7	-0.1	0.7	-0.8	0.9	-0.5	-1.0	-1.2	-0.5	-0.7	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.8	-1.0	-0.2	-1.4	-0.9	0.6	-0.7	-0.9	-0.3	-0.9	-1.1	-0.2
Forced vital capacity (FVC)	0.4	1.4	3.3	1.6	0.3	0.5	1.8	0.1	1.2	1.4	0.3	1.7	1.6	0.7
Fluid intelligence score	0.4	0.8	4.5	0.7	2.1	1.2	0.2	0.6	1.1	-0.2	-0.2	0.1	0.9	-0.4
Neuroticism score	0.4	0.8	3.3	0.3	-1.1	0.5	-0.1	0.9	0.1	1.0	1.8	0.3	-0.3	1.3
Noisy workplace	0.4	0.5	1.6	-0.3	-0.3	-0.0	-0.1	-0.9	-1.3	-1.0	-1.0	-0.6	-0.4	-0.7
Birth weight of first child	0.4	0.6	2.7	-0.5	0.7	0.5	-0.4	-0.4	0.7	-0.5	-0.9	1.2	-0.2	-1.7
Peak expiratory flow (PEF)	0.4	0.8	2.8	-0.4	-1.1	-1.3	-0.1	-1.7	-1.2	-0.6	-1.0	-0.5	-0.4	-0.6
Pulse wave reflection index	0.4	0.5	1.2	-1.1	-0.3	-0.5	-0.6	0.5	-0.8	-1.1	-0.8	-0.5	-0.8	-0.6
Forced vital capacity (FVC), Best measure	0.4	1.3	3.5	1.7	0.3	0.7	1.9	0.3	1.2	1.2	0.0	0.9	1.6	0.7
Comparative body size at age 10	0.4	1.1	4.7	-0.5	-0.0	-0.1	0.3	0.6	-0.8	0.9	2.2	0.9	-0.1	2.1
Angina (self-reported)	0.4	0.6	1.9	-0.1	-0.5	0.6	-0.7	-0.5	0.3	-0.9	-1.2	-0.8	-0.3	-1.4
Migraine (self-reported)	0.4	0.5	1.2	1.0	0.3	0.9	1.1	0.0	0.4	0.2	-0.8	-1.1	0.8	0.1
Comparative height size at age 10	0.4	2.3	4.7	1.0	1.3	1.7	0.9	1.5	1.9	1.9	1.7	2.2	1.0	1.1
Had major operations	0.4	0.5	1.2	0.1	0.8	0.2	-0.1	1.1	0.3	-0.4	-0.9	-1.1	0.1	-0.9
Medication: Aspirin	0.4	0.6	2.4	-0.3	0.5	-1.1	-0.6	-1.6	-0.7	-0.6	-0.6	-0.0	-0.6	-0.7
Hypertension (Self-reported)	0.4	1.0	4.7	-0.2	0.9	-0.3	-0.6	1.5	0.2	0.6	2.2	-0.2	-0.6	1.4
Ever had bowel cancer screening	0.4	0.4	1.4	-0.4	0.7	-0.8	-0.7	0.8	-0.0	-0.3	-0.1	1.2	-0.5	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.6	-0.4	-0.7	0.8	-0.8	1.3	0.2	0.3	0.4	0.6	-0.6	-0.5
Number of self-reported non-cancer illnesses	0.4	0.7	2.8	0.3	1.7	0.6	-0.1	1.3	0.4	0.6	1.2	-0.2	-0.1	0.5
Hearing aid user	0.4	0.4	1.7	-0.2	0.7	0.4	0.2	-0.8	-0.1	-0.8	-1.3	-0.3	-0.0	-0.8
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.3	0.1	-1.2	1.0	-0.2	-0.1	-0.2	1.0	0.9	1.0	-0.2	0.2
Average weekly beer plus cider intake	0.4	0.5	1.1	0.8	0.2	-1.0	0.8	-0.2	1.0	1.0	0.5	0.4	0.9	0.5
Risk taking	0.4	0.6	5.7	0.3	-0.1	0.4	0.3	-0.2	-0.1	-0.3	-0.7	-2.4	0.0	-0.1
Impedance of whole body	0.4	2.1	5.1	-1.3	-0.9	-0.4	-1.3	-1.5	-0.4	-1.9	-2.3	-1.2	-1.1	-2.2
Worry (Nagel 2018)	0.3	0.7	2.9	-0.1	-1.2	0.5	-0.4	1.0	0.2	0.7	1.7	0.2	-0.3	0.9
Alzheimer’s Disease (in mother)	0.3	0.4	1.9	0.3	-0.8	0.2	0.5	-0.7	0.0	0.7	0.3	1.4	0.3	0.4
Ulcerative Colitis (UC)	0.3	0.6	1.6	0.7	0.5	0.6	1.1	-0.3	1.3	0.1	-0.5	1.1	1.1	-0.2
Primary Biliary Cirrhosis	0.3	0.5	1.2	-0.3	-0.5	-0.8	-0.6	-0.5	-0.8	-1.1	-0.7	-0.2	-0.8	-0.8
Ulcerative Colitis	0.3	0.4	1.7	0.5	0.4	-0.0	0.6	0.3	0.9	0.3	0.6	1.3	0.4	0.6
Blood Eosinophil Count	0.3	2.4	7.7	-2.0	-2.1	-2.8	-2.0	1.2	-0.6	-0.9	-0.0	-0.4	-1.7	-0.8
Blood Platelet Count	0.3	3.6	7.8	-1.7	-2.4	-2.6	-2.2	0.6	-1.6	0.6	2.8	0.3	-2.5	1.5
Height	0.3	6.3	17.6	1.1	0.9	1.5	0.8	3.9	1.7	3.3	4.2	3.2	1.4	2.5
Allergy or Eczema	0.3	0.7	2.1	-0.9	-0.5	-0.5	-0.8	-0.5	-0.4	-1.1	-1.2	-0.2	-0.6	-1.4
Respiratory disease	0.3	0.8	5.2	0.6	2.3	-0.1	0.0	1.4	0.1	0.3	0.5	0.4	-0.1	0.2
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.4	-0.6	0.2	-0.6	-0.6	1.2	-0.5	-0.6	0.1	-1.2	-0.8	0.1
Hand grip strength (left)	0.3	0.7	2.6	-0.5	-0.4	0.1	-0.6	1.6	-0.1	0.5	1.4	1.5	-0.4	0.2
Average weekly spirits intake	0.3	0.3	1.3	-0.6	0.7	-0.1	-0.2	-1.1	-0.6	-0.6	-0.6	-0.4	-0.5	-0.1
Angina	0.3	0.4	1.2	-0.2	-0.4	0.3	-0.6	-0.5	0.1	-0.8	-1.0	-1.0	-0.3	-1.1
Medication: Co-codamol	0.3	0.4	1.9	-0.2	-0.1	0.1	-0.1	-0.4	-0.4	0.4	1.4	1.0	-0.3	0.8
Hand grip strength (right)	0.3	0.8	3.7	-0.1	0.3	0.0	0.1	1.3	-0.5	0.8	1.9	0.7	-0.0	1.5
Townsend deprivation index at recruitment	0.3	0.4	1.0	0.2	1.0	-1.0	0.1	-0.9	0.1	-0.1	-0.6	0.4	0.2	-0.8
High blood pressure	0.3	0.9	4.4	0.0	1.1	-0.0	-0.3	1.3	0.4	0.7	2.1	-0.2	-0.3	1.5
Stomach or abdominal pain in last month	0.3	0.4	1.1	0.5	1.0	-0.4	0.2	0.5	0.8	0.7	1.0	0.2	0.3	0.4
Medication: Levothyroxine sodium	0.3	0.5	1.1	-0.8	0.3	-1.0	-0.8	-0.4	-1.0	-0.4	0.3	1.0	-1.0	-0.2
Nervous feelings	0.3	0.5	1.7	0.5	-0.6	1.1	0.1	-1.1	1.3	0.6	0.4	-0.3	0.7	0.0
Had other major operations	0.3	0.4	0.8	0.8	0.3	0.7	0.9	-0.9	0.4	0.3	-0.8	0.6	0.7	-0.2
Allergy	0.3	0.6	5.2	-0.5	-2.3	-0.6	-0.5	-0.5	-0.4	-0.2	0.1	0.5	-0.5	-0.2
Impedance of arm (right)	0.3	1.3	4.7	0.4	0.6	1.1	0.5	-1.4	1.1	-0.8	-2.2	-1.3	0.5	-1.5
Father’s age at death	0.3	0.3	1.0	0.4	-0.9	0.6	0.6	-1.0	-0.3	0.7	0.3	0.3	0.2	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.1	1.0	1.0	-0.9	0.6	-1.0	-0.3	0.1	-0.3	-0.2	0.5	0.2
Falls in the last year	0.3	0.4	2.4	0.3	-0.0	0.8	0.2	-1.6	-0.4	0.6	0.6	0.4	-0.3	0.4
Standing height	0.3	3.1	7.2	0.7	1.3	1.1	0.6	2.5	1.3	2.4	2.7	2.7	1.0	1.3
Tense / ‘highly strung’	0.3	0.5	2.2	-0.3	-0.6	-0.3	-0.5	-0.1	-0.7	-0.2	0.8	-1.5	-0.7	0.9
Medication for pain relief, constipation, heartburn	0.3	0.6	3.6	0.1	0.2	0.4	0.8	1.9	0.8	-0.5	-0.6	-0.4	0.6	0.5
Medication: Seretide 50 evohaler	0.3	0.4	1.0	0.4	0.9	0.2	0.7	-0.6	-0.8	-0.0	-0.3	-1.0	0.3	0.5
Alcohol intake frequency.	0.3	0.7	2.5	-0.5	0.0	-1.6	-0.6	0.4	-1.0	0.4	1.3	-0.1	-0.8	0.8
Leg pain on walking	0.3	0.4	1.2	0.9	0.8	1.0	0.5	-0.5	-0.1	-0.1	-1.1	-0.4	0.5	-0.5
Illnesses of siblings: Diabetes	0.3	0.4	1.3	-0.4	0.4	-0.3	-0.2	1.1	-0.5	0.1	0.7	-0.2	-0.7	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	4.2	0.5	2.0	0.0	1.1	-0.0	0.5	0.5	-0.1	1.0	0.8	0.2
Loneliness, isolation	0.3	0.4	1.2	0.3	-0.3	1.1	0.2	-1.0	0.0	-0.4	-1.1	0.3	0.1	-0.8
Commuting to job workplace: Walk	0.3	0.3	1.5	-0.1	1.2	-0.4	0.0	0.8	-0.7	-0.3	0.2	-0.1	-0.1	0.8
Back pain experienced in last month	0.3	0.5	2.3	0.1	-1.0	1.5	-0.1	-0.3	-0.3	-0.0	-0.4	-1.3	-0.4	0.2
Guilty feelings	0.3	0.4	1.1	-0.4	-1.1	0.9	-0.5	-0.4	-0.2	0.3	0.7	1.1	-0.6	-0.0
Mother’s age at death	0.3	0.4	1.7	0.6	0.6	1.3	0.6	0.3	0.3	0.3	-0.2	-0.3	0.9	0.3
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.7	0.5	-1.0	1.3	-0.1	-0.8	-0.2	-0.1	-0.8	0.1	0.1	-0.6
Alcohol drinker status: Never	0.3	0.3	1.1	1.0	0.0	0.9	0.4	-0.3	1.0	0.2	-0.4	0.4	0.5	-0.2
Fractured/broken bones in last 5 years	0.3	0.4	1.9	-0.1	-0.6	-0.9	0.1	0.4	0.1	-0.2	-0.4	1.4	-0.1	-0.7
Cholesterol lowering medication	0.3	0.4	0.9	-0.7	-0.1	-0.1	-0.6	0.6	-0.9	-0.4	0.8	-0.1	-0.9	0.7
Neuroticism (Nagel 2018)	0.2	0.5	1.3	-0.8	-1.1	-0.1	-0.8	0.3	-0.4	0.1	1.1	0.8	-1.0	0.0
Crohns Disease (2017)	0.2	0.4	1.9	0.0	-0.8	0.4	-0.0	-1.4	-0.6	-0.7	-0.8	-0.0	-0.2	-0.5
Irritable Bowel Disease (IBD)	0.2	0.4	1.0	0.5	-0.4	0.5	0.8	-1.0	0.6	-0.2	-0.6	1.0	0.6	-0.3
Prostate Cancer	0.2	0.2	0.7	-0.2	0.3	0.1	-0.3	-0.4	-0.1	-0.7	-0.6	-0.9	-0.2	-0.5
Crohns Disease (2012)	0.2	0.3	1.3	0.5	-0.2	0.8	0.5	-1.1	0.2	0.2	-0.6	0.7	0.4	-0.1
Fasting Glucose	0.2	0.3	1.1	0.3	0.4	1.1	0.6	-0.3	-0.1	-0.4	-0.3	-0.6	0.4	0.6
HDL Cholesterol	0.2	0.3	1.9	-0.3	-0.1	-1.4	-0.2	-0.4	0.1	-0.1	0.0	1.1	0.2	-0.3
Triglycerides	0.2	0.4	2.2	0.6	0.1	1.5	0.2	-0.4	0.5	0.4	-0.5	-0.4	0.5	-0.4
Smoking Status	0.2	0.5	2.0	-0.4	0.0	-0.8	-0.6	1.4	0.4	0.7	1.3	0.5	-0.0	0.3
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.7	-0.5	0.5	0.1	-0.1	-0.6	-0.3	-1.0	-1.3	-0.7	-0.2	-0.9
Sitting height	0.2	1.8	4.4	1.1	1.6	1.4	0.6	1.7	1.4	1.4	1.0	2.1	1.2	0.1
Hearing difficulty/problems with background noise	0.2	0.4	1.4	0.1	-0.4	0.4	-0.3	-1.2	0.0	-0.2	-0.9	0.7	-0.3	-1.0
Hair/balding pattern: Pattern 2	0.2	0.3	0.7	0.3	0.1	0.8	0.5	0.4	0.6	0.6	0.3	0.7	0.5	0.0
Time employed in main current job	0.2	0.2	1.0	0.3	-0.2	-0.1	0.4	-0.6	0.7	-0.3	-1.0	-0.4	0.4	-0.4
Number of live births	0.2	0.3	1.1	0.7	-0.0	0.9	0.4	1.1	0.7	0.2	-0.0	-0.2	0.3	0.1
Pulse rate	0.2	0.4	1.6	-0.0	-0.8	0.7	-0.6	-1.2	-0.9	0.1	0.3	-0.4	-0.5	0.5
Prospective memory result	0.2	0.3	0.6	-0.3	-0.6	-0.8	-0.7	0.7	0.2	-0.3	0.2	0.7	-0.4	-0.4
Impedance of arm (left)	0.2	1.1	4.5	-0.0	-0.1	0.5	0.0	-1.5	0.7	-1.0	-2.1	-0.7	0.1	-1.6
Shortness of breath walking on level ground	0.2	0.3	0.6	-0.5	0.8	-0.4	-0.7	0.1	-0.4	-0.7	-0.0	-0.3	-0.6	-0.3
Emphysema/chronic bronchitis	0.2	0.2	1.0	-0.3	0.0	-0.1	-0.5	-0.1	-1.0	-0.2	0.4	0.2	-0.8	0.3
Eye problems/disorders: Cataract	0.2	0.2	0.6	-0.4	0.2	0.1	-0.6	-0.8	-0.3	-0.2	0.6	0.4	-0.4	0.3
Osteoporosis (self-reported)	0.2	0.2	1.0	0.4	0.3	0.2	0.4	-0.0	1.0	0.2	-0.4	0.1	0.8	-0.7
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.9	-0.2	-0.1	0.8	-0.3	0.4	0.8	0.3	0.1	0.9	-0.1	-0.5
Medication: Blood pressure	0.2	0.4	1.4	-0.3	0.1	-0.0	-0.6	-0.4	-0.9	-0.2	1.2	-0.1	-0.8	1.1
Medication: Atorvastatin	0.2	0.3	1.3	-0.6	-0.3	0.0	-0.7	0.0	-0.5	-0.5	0.1	-1.2	-0.6	0.5
Age started oral contraceptive pill	0.2	0.3	1.1	-0.1	1.1	0.2	0.4	0.1	0.0	-0.3	-0.5	-1.0	0.1	0.7
Vascular/heart problems diagnosed by doctor	0.2	0.5	2.4	0.1	-0.7	-0.1	0.4	-1.0	-0.3	-0.4	-1.6	0.4	0.4	-1.0
Pain experienced in last month	0.2	0.4	1.6	-0.3	-0.9	-0.8	0.4	-0.0	-0.5	-0.9	-1.2	-0.5	0.1	-0.3
Supplements: Calcium	0.2	0.2	0.9	0.4	0.2	-0.5	0.2	-0.3	0.5	0.5	0.1	1.0	0.1	-0.3
Depressed Affect (Nagel 2018)	0.1	0.2	0.8	-0.0	-0.2	0.0	-0.3	0.1	0.2	-0.2	-0.2	0.9	-0.6	-0.7
Schizophrenia vs Biploar Disorder	0.1	0.2	0.7	-0.1	0.6	0.1	-0.0	0.3	0.6	0.1	0.3	0.9	0.4	-0.1
Neuroticism (2016)	0.1	0.2	0.6	-0.1	-0.2	0.1	-0.1	0.7	-0.3	0.3	0.6	-0.8	-0.2	0.7
Heel T-Score	0.1	0.7	3.3	-0.1	-0.3	0.1	-0.4	0.4	-0.3	0.6	1.5	1.8	-0.5	0.6
Waist Hip Ratio (WHR)	0.1	0.4	1.5	0.1	-0.6	-0.1	-0.6	-0.4	1.0	-0.3	-0.4	1.2	0.1	-1.1
Tanning	0.1	1.0	2.1	-1.3	0.6	-1.3	-1.3	-0.1	0.1	-0.8	-0.1	1.4	-1.1	-1.4
Eye problems/disorders: Diabetes related eye disease	0.1	0.2	0.4	0.0	0.0	-0.1	0.6	-0.6	-0.2	0.2	-0.4	-0.5	0.3	0.6
Average weekly fortified wine intake	0.1	0.2	0.6	-0.3	0.7	-0.3	-0.3	-0.8	-0.1	-0.3	-0.3	0.2	-0.1	-0.5
Age when periods started (menarche)	0.1	0.4	1.5	0.4	0.8	-0.4	-0.1	1.2	0.9	0.5	0.4	0.2	0.4	0.0
Qualifications: CSEs or equivalent	0.1	0.1	0.4	0.5	-0.6	-0.1	0.6	-0.0	-0.3	-0.0	-0.2	0.1	0.1	0.4
Had menopause	0.1	0.2	0.6	-0.6	0.0	-0.1	-0.5	-0.6	0.1	-0.2	0.3	0.8	-0.5	0.0
Financial difficulties in last 2 years	0.1	0.2	1.0	0.1	0.4	-0.1	0.4	-0.4	0.3	0.4	0.2	1.0	0.2	0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.5	0.9	-0.3	0.2	1.2	-0.5	0.6	0.4	-0.7	0.8	1.0	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.0	0.9	-0.6	0.1	1.0	-0.3	0.6	0.2	-0.9	0.1	0.9	-0.1
Neck or shoulder pain in last month	0.1	0.1	0.3	0.3	0.3	0.5	0.0	-0.5	0.4	0.5	0.1	0.5	0.1	-0.3
Suffer from ‘nerves’	0.1	0.2	0.3	-0.3	-0.1	0.3	-0.3	0.4	-0.5	-0.1	0.5	-0.6	-0.4	0.4
Age at last live birth	0.1	0.1	0.4	-0.3	0.4	0.0	-0.2	-0.3	-0.0	-0.7	-0.6	-0.5	-0.1	-0.3
Mood swings	0.1	0.2	0.9	0.3	0.3	-0.3	0.0	0.9	0.3	0.5	0.8	0.3	0.0	0.5
Medication for cholesterol	0.1	0.2	0.7	-0.2	-0.2	-0.4	-0.2	0.3	0.9	0.1	-0.5	-0.4	0.1	-0.8
Hair Pigment	0.0	0.8	3.1	0.5	-1.2	1.1	0.2	1.8	0.9	0.8	0.8	1.0	0.0	0.1

Hub : Genes

KIF20B

Models

Trait associations