TWAS hub - KLRC1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0256	0.0097	8.3e-04	0.009	0.008	0.020	0.012	0.023	4.7e-04	7.8e-04	2.5e-07	8.6e-05	4.9e-08
2	TCGA	Bladder Urothelial Carcinoma	0.1510	0.0620	2.3e-08	0.084	0.119	0.122	NA	0.104	1.3e-07	3.2e-10	1.9e-10	NA	4.3e-09
3	TCGA	Breast Invasive Carcinoma	0.0462	0.0195	1.4e-10	0.034	0.055	0.051	NA	0.051	1.5e-07	2.2e-11	1.3e-10	NA	1.2e-10
4	TCGA	Head and Neck Squamous Cell Carcinoma	0.0220	0.0152	5.9e-03	0.005	0.004	0.004	NA	0.004	8.6e-02	1.1e-01	9.6e-02	NA	1.0e-01
5	TCGA	Kidney Renal Clear Cell Carcinoma	0.0548	0.0237	2.8e-08	0.075	0.076	0.076	NA	0.074	8.1e-09	6.2e-09	7.2e-09	NA	1.0e-08
6	TCGA	Brain Lower Grade Glioma	0.0648	0.0305	2.0e-05	0.002	0.043	0.034	NA	0.018	1.7e-01	1.0e-05	8.5e-05	NA	3.3e-03
7	TCGA	Lung Adenocarcinoma	0.0270	0.0137	7.4e-05	0.012	0.038	0.031	NA	0.026	1.3e-02	2.8e-05	1.3e-04	NA	4.1e-04
8	TCGA	Lung Squamous Cell Carcinoma	0.0274	0.0161	8.6e-04	0.023	0.028	0.020	NA	0.019	1.1e-03	3.1e-04	1.9e-03	NA	2.7e-03
9	TCGA	Ovarian Serous Cystadenocarcinoma	0.0390	0.0250	3.5e-03	0.052	0.028	0.028	NA	0.033	1.9e-04	4.9e-03	4.8e-03	NA	2.6e-03
10	TCGA	Prostate Adenocarcinoma	0.0823	0.0348	1.3e-10	0.091	0.095	0.096	NA	0.090	9.9e-10	4.2e-10	2.9e-10	NA	1.1e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Medication: Bendroflumethiazide	5.9	9.0	13.4	3.3	2.0	2.6	3.3	2.8	2.6	2.7	3.7	3.3	3.5
Unable to work because of sickness or disability	5.6	7.2	9.8	-3.1	-2.4	-2.4	-2.7	-2.6	-2.6	-2.4	-3.0	-2.7	-2.8
Blood Red Count	4.7	45.5	60.6	-6.3	-6.6	-7.8	-6.2	-7.8	-5.7	-7.8	-6.4	-5.8	-6.7
Loud music exposure frequency	4.6	5.1	7.7	-2.1	-1.9	-2.4	-2.4	-2.5	-1.7	-2.8	-2.6	-2.0	-2.0
Falls in the last year	4.4	5.9	9.7	-2.2	-1.6	-1.7	-3.1	-2.1	-2.5	-2.2	-3.0	-2.7	-2.7
Bipolar Disorder (2011)	3.8	3.7	5.6	-2.4	-1.9	-1.6	-1.7	-1.9	-1.8	-1.8	-2.2	-1.9	-1.9
Alzheimer’s Disease (including proxy)	3.2	4.6	6.9	-1.7	-1.5	-2.2	-2.6	-2.3	-1.9	-2.4	-2.2	-2.2	-2.1
Bilateral oophorectomy (both ovaries removed)	3.1	3.6	8.9	0.0	0.1	-1.6	-3.0	-1.5	-0.8	-1.8	-2.2	-2.9	-2.3
Financial situation satisfaction	3.1	3.9	5.6	2.3	1.9	2.0	1.5	2.2	1.3	2.0	2.1	1.6	2.4
Medication: Co-codamol	3.0	3.5	9.3	1.8	1.8	2.0	1.8	2.1	3.1	1.5	1.5	0.9	1.5
Illness, injury, bereavement, stress in last 2 years	2.9	3.6	5.7	-2.2	-2.2	-2.4	-1.3	-2.2	-1.9	-2.1	-1.5	-1.4	-1.3
Hearing difficulty/problems: Yes	2.7	4.1	6.2	-2.2	-1.9	-1.8	-1.7	-2.0	-1.7	-1.9	-2.4	-2.1	-2.5
Blood Platelet Count	2.6	29.9	44.8	5.3	5.7	6.7	4.0	6.5	4.7	6.3	5.1	4.2	5.4
Prospective memory result	2.6	3.1	4.2	-1.6	-1.8	-1.9	-2.0	-2.0	-2.0	-1.9	-1.4	-1.3	-1.7
Hypothyroidism/myxoedema (self-reported)	2.4	4.7	11.6	-3.4	-2.3	-2.1	-1.6	-2.3	-2.3	-1.8	-1.9	-1.2	-2.0
Supplements: Zinc	2.3	2.5	4.5	1.5	1.2	1.5	1.8	1.8	1.1	2.1	1.7	1.2	1.6
Had other major operations	2.3	2.8	4.5	-1.7	-0.9	-1.4	-1.9	-1.5	-0.9	-1.6	-2.1	-2.0	-2.0
Number of children fathered	2.3	2.6	4.6	-0.7	-0.6	-2.1	-1.6	-1.8	-1.0	-1.7	-1.7	-2.1	-1.9
Comparative body size at age 10	2.0	5.6	10.2	1.4	1.3	3.2	2.4	2.9	2.2	2.5	2.2	2.2	2.6
Ever taken oral contraceptive pill	2.0	2.2	4.4	2.1	1.9	2.0	0.7	1.9	1.5	1.6	0.6	0.5	0.7
Cholesterol lowering medication	2.0	2.9	6.7	-2.6	-2.5	-1.4	-0.0	-1.7	-2.2	-0.9	-1.5	-0.8	-1.7
Lung cancer (father)	1.9	2.2	4.0	-2.0	-1.0	-1.4	-1.0	-1.3	-1.3	-1.1	-1.8	-1.8	-1.5
Guilty feelings	1.9	2.9	7.1	1.0	0.2	1.4	2.7	1.7	0.6	2.1	2.0	2.1	1.7
Heart disease (siblings)	1.9	2.4	4.3	-0.6	-0.5	-1.5	-1.9	-1.5	-0.5	-1.7	-1.8	-2.1	-2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.8	4.6	1.8	1.7	1.9	1.4	2.1	1.4	2.1	1.4	1.1	1.4
Illnesses of father: Heart disease	1.8	2.5	4.4	0.4	0.7	2.1	1.6	1.8	0.7	2.0	1.7	1.7	2.0
Myopia	1.8	2.5	5.8	2.4	2.4	1.6	-0.2	1.8	2.3	0.9	1.2	0.1	1.1
Hair/balding pattern: Pattern 3	1.7	2.6	4.9	0.9	0.9	1.7	2.2	1.8	1.2	2.1	1.6	1.8	1.4
Heart attack/myocardial infarction (self-reported)	1.7	2.2	5.2	-0.3	-0.6	-0.9	-1.9	-1.1	-0.2	-1.6	-2.0	-2.3	-2.0
Heart attack	1.6	2.1	4.8	-0.5	-0.6	-0.8	-1.8	-1.1	-0.4	-1.5	-2.0	-2.2	-2.0
Diabetes (self-reported)	1.6	2.5	4.3	2.0	1.6	2.1	1.1	2.1	1.8	1.8	0.9	0.6	0.9
Illnesses of siblings	1.5	2.1	3.3	0.9	1.2	1.5	1.2	1.7	1.6	1.5	1.8	1.2	1.5
Medication for pain relief, constipation, heartburn	1.5	2.6	3.9	1.8	1.4	1.6	1.2	1.6	1.8	1.3	2.0	1.6	1.7
Supplements: Calcium	1.5	1.6	3.9	0.4	0.1	0.9	2.0	1.0	0.6	1.6	1.7	1.7	1.4
Allergy or Eczema	1.4	3.7	5.2	2.2	0.5	2.0	2.3	2.0	2.0	1.5	2.1	1.8	2.2
Diverticular disease/diverticulitis (self-reported)	1.4	1.6	4.3	1.4	1.4	1.2	0.7	1.3	2.1	0.8	1.3	0.8	1.1
Pulse rate	1.4	2.3	3.5	-0.7	-0.6	-1.8	-1.9	-1.6	-0.5	-1.8	-1.6	-1.9	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	3.0	1.7	1.5	1.1	0.9	1.4	1.6	1.2	1.1	0.3	0.9
Ever used hormone-replacement therapy (HRT)	1.3	1.6	5.0	0.0	-0.1	-1.0	-1.4	-0.8	-0.2	-1.0	-1.7	-2.2	-1.8
Medication: Metformin	1.3	1.8	3.1	1.5	1.4	1.7	1.1	1.8	1.2	1.8	0.8	0.6	1.0
Medication: Ramipril	1.3	1.7	3.6	1.6	1.9	1.3	0.3	1.4	1.8	1.1	1.0	0.1	1.1
Illnesses of mother	1.3	1.6	4.0	-0.2	-0.3	1.2	1.9	0.9	-0.3	1.6	1.5	2.0	1.0
Pulse wave reflection index	1.3	1.6	5.4	0.3	-0.2	0.8	1.4	0.6	-0.7	0.9	1.8	2.3	1.9
Gout (self-reported)	1.3	1.8	5.6	0.5	1.1	1.9	1.1	1.8	2.4	1.2	0.9	0.3	0.8
Smoking status: Current	1.3	2.0	3.3	1.8	1.2	1.6	1.3	1.6	1.6	1.2	1.3	1.1	1.3
Miserableness	1.3	2.3	2.7	1.6	1.3	1.6	1.6	1.6	1.5	1.6	1.5	1.4	1.4
Multivitamins +/- minerals	1.2	1.5	3.7	0.7	0.9	1.3	1.0	1.2	-0.3	1.9	1.4	1.3	1.2
Allergy	1.2	2.8	4.4	-1.2	-0.4	-1.7	-2.1	-1.8	-1.4	-1.6	-2.0	-2.0	-1.9
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.6	3.4	-1.7	-1.4	-1.4	-0.6	-1.3	-1.8	-0.9	-1.1	-0.7	-1.0
Alcohol drinker status: Never	1.2	1.5	3.3	-1.8	-1.6	-1.2	-0.6	-1.4	-1.8	-1.2	-0.5	0.2	-0.4
Average weekly beer plus cider intake	1.2	1.7	3.9	0.7	0.2	0.8	2.0	1.0	1.1	0.9	1.7	1.7	1.6
Alzheimer’s Disease (in father)	1.1	1.2	3.1	-0.8	-0.5	-1.0	-1.8	-1.1	-1.1	-1.1	-1.1	-1.1	-1.1
Type 2 Diabetes (T2D) (2018)	1.1	2.0	4.4	1.8	1.4	2.1	0.7	2.1	1.3	1.8	0.4	0.3	0.6
Severe depression (siblings)	1.1	1.3	2.0	-0.8	-1.1	-1.3	-0.8	-1.2	-1.1	-1.0	-1.4	-1.2	-1.2
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	3.7	0.1	-1.0	0.7	1.0	0.5	-1.0	0.7	1.3	1.9	1.6
Alcohol usually taken with meals	1.1	1.7	2.8	-1.7	-1.2	-1.3	-1.0	-1.6	-1.7	-1.0	-1.1	-0.9	-1.4
Hearing difficulty/problems with background noise	1.1	1.8	3.6	-0.8	-0.3	-1.8	-1.2	-1.3	-0.8	-1.1	-1.5	-1.9	-1.7
Medication: Ventolin 100micrograms inhaler	1.1	1.4	3.1	1.8	0.9	0.5	1.2	1.0	1.0	0.9	1.5	1.4	1.2
Mouth/teeth dental problems: Loose teeth	1.1	1.3	2.2	0.8	0.3	1.3	1.3	1.5	0.6	1.4	1.2	1.3	1.3
Triglycerides	1.0	1.7	2.4	1.2	1.0	1.2	1.4	1.2	1.0	1.2	1.4	1.5	1.6
Blood Eosinophil Count	1.0	7.6	12.9	2.0	2.3	2.9	2.6	3.0	1.0	3.6	3.1	3.1	3.1
Current tobacco smoking	1.0	1.6	2.8	1.7	1.2	1.5	0.9	1.4	1.5	1.0	1.0	0.8	1.1
Hayfever, allergic rhinitis or eczema	1.0	2.1	4.5	1.3	-0.3	1.4	2.1	1.4	1.0	1.1	1.7	1.8	1.7
High blood pressure (mother)	1.0	1.4	3.9	1.8	1.6	1.1	-0.2	1.2	2.0	0.6	0.4	-0.6	0.3
Number of incorrect matches in round	1.0	1.7	2.5	-1.0	-0.9	-1.3	-1.4	-1.4	-0.7	-1.6	-1.6	-1.4	-1.5
Qualifications: O levels/GCSEs or equivalent	1.0	1.7	5.3	-2.3	-1.8	-0.9	-0.4	-1.2	-1.5	-1.0	-1.1	-0.2	-0.8
Leg fat percentage (right)	1.0	3.6	10.3	-0.7	-0.1	-1.3	-2.6	-1.3	-0.9	-1.4	-2.6	-3.2	-2.4
Migraine (self-reported)	1.0	1.2	3.2	-0.9	-0.7	-0.9	-1.8	-1.1	-0.8	-1.7	-1.1	-0.8	-0.9
Diabetes diagnosed by doctor	1.0	1.6	3.3	1.8	1.5	1.8	0.4	1.7	1.6	1.3	0.4	0.1	0.6
Bipolar Disorder (2018)	0.9	1.4	3.1	-1.4	-1.3	-1.1	-1.1	-1.2	-1.8	-1.1	-1.1	-0.4	-0.9
Depressed Affect (Nagel 2018)	0.9	1.9	4.7	0.8	1.1	1.6	1.6	1.7	0.6	2.2	1.1	1.2	1.1
Schizophrenia (2018)	0.9	1.9	3.5	1.3	1.7	0.9	0.9	1.3	0.5	1.6	1.9	1.4	1.6
Schizophrenia vs Biploar Disorder	0.9	1.2	3.3	1.8	1.8	0.8	0.0	1.1	1.3	1.0	0.9	0.1	0.6
Primary Biliary Cirrhosis	0.9	1.3	3.6	-0.2	0.0	0.8	1.9	0.8	0.3	1.3	1.2	1.9	1.2
Relative age voice broke	0.9	1.4	7.5	-1.0	-1.3	-1.3	-0.0	-1.2	-2.7	-0.3	-0.1	1.0	-0.1
Medication: Levothyroxine sodium	0.9	1.5	4.8	-2.2	-1.6	-1.3	-0.3	-1.3	-1.3	-1.0	-0.7	-0.3	-0.8
Depression (self-reported)	0.9	1.1	2.3	1.2	1.2	1.3	0.8	1.3	1.0	1.5	0.4	0.1	0.3
Tense / ‘highly strung’	0.9	1.5	2.3	-1.3	-1.5	-1.4	-1.0	-1.2	-1.0	-1.2	-1.2	-1.0	-1.3
Emphysema/chronic bronchitis	0.9	1.0	2.4	1.3	1.5	1.0	0.0	1.1	0.4	1.0	1.0	0.8	1.0
Medication: Ibuprofen	0.9	1.0	2.0	-1.4	-1.2	-1.1	-0.4	-1.1	-1.2	-0.8	-1.1	-0.6	-0.9
Chest pain or discomfort	0.9	1.3	2.1	1.5	1.1	0.9	0.8	1.4	0.9	1.4	1.2	0.7	1.2
Medication: Gliclazide	0.9	1.0	1.7	1.0	1.2	1.2	1.0	1.1	1.3	1.1	0.4	0.3	0.4
Illnesses of father: None of the above (group 1)	0.9	1.1	3.0	-0.6	-0.5	-1.7	-0.5	-1.4	-0.4	-1.1	-0.8	-1.0	-1.3
Ever had prostate specific antigen (PSA) test	0.9	1.0	2.0	1.0	0.7	0.6	1.2	1.0	1.4	0.9	1.1	0.6	1.1
Ulcerative Colitis	0.8	1.1	3.0	0.8	-0.2	0.4	1.2	0.5	0.3	0.4	1.6	1.7	1.7
Angina	0.8	1.1	2.7	-0.6	-0.6	-0.4	-1.6	-0.8	-0.6	-1.2	-1.4	-1.3	-1.1
Townsend deprivation index at recruitment	0.8	1.1	3.5	0.3	0.9	1.9	0.8	1.5	0.6	1.5	0.3	0.5	0.6
Financial difficulties in last 2 years	0.8	1.1	2.2	0.5	1.1	1.4	1.0	1.4	1.5	1.3	0.6	0.2	0.5
Noisy workplace	0.8	1.0	1.8	-0.1	-1.0	-1.0	-1.1	-1.0	-1.4	-1.1	-1.1	-1.0	-0.9
Exposure to tobacco smoke at home	0.8	0.9	3.0	0.8	1.1	-0.2	-1.7	-0.3	0.0	-0.6	-0.8	-1.3	-0.9
Hair/balding pattern: Pattern 4	0.8	1.8	3.6	-0.0	0.0	-1.9	-1.9	-1.5	-0.6	-1.6	-1.0	-1.6	-1.5
Blood clot in the leg (DVT)	0.8	1.0	2.5	1.5	1.2	0.9	0.7	1.0	1.6	0.5	0.9	0.7	0.8
Medication: Allopurinol	0.8	1.1	2.9	0.2	0.7	1.7	0.8	1.4	1.7	1.0	0.6	0.3	0.6
Medication: Seretide 50 evohaler	0.8	0.9	2.0	0.4	1.1	1.1	1.1	1.2	1.0	1.4	0.7	0.5	0.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	3.2	1.5	1.2	0.7	0.6	0.9	1.8	0.4	0.9	0.5	0.7
Mean Putamen Volume	0.7	0.8	1.8	-0.1	-0.5	-0.5	-1.2	-0.7	-1.1	-0.7	-1.3	-1.3	-0.9
Stomach or abdominal pain in last month	0.7	0.9	2.5	-1.1	-1.1	-1.5	0.0	-1.1	-1.6	-0.4	-0.2	0.1	-0.5
Medication: Atenolol	0.7	0.9	2.8	1.7	1.3	0.8	0.6	0.9	1.0	0.9	0.5	0.3	0.5
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.1	1.2	0.9	1.1	0.6	1.1	0.6	1.0	1.3	1.2	1.5
Medication: Cholesterol lowering	0.7	1.2	3.3	1.8	1.5	0.7	0.7	1.0	1.5	0.8	0.8	0.1	0.8
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	4.1	-1.6	-1.8	-0.9	0.0	-0.9	-2.0	-0.3	-0.2	0.7	-0.2
Birth weight	0.7	1.6	3.6	-0.6	-0.5	-1.0	-1.4	-1.0	1.0	-1.9	-1.2	-1.8	-1.4
Medication: Blood pressure	0.7	1.2	4.3	1.2	1.8	1.2	-0.3	1.0	2.1	0.4	-0.2	-0.7	-0.1
Pulse rate, automated reading	0.7	2.3	4.8	-0.4	0.1	-1.4	-2.2	-1.3	-0.4	-1.5	-1.8	-2.2	-1.8
Number of full sisters	0.7	0.9	3.2	-0.5	0.1	-0.1	-1.1	-0.3	0.1	-0.5	-1.3	-1.8	-1.3
Suffer from ‘nerves’	0.7	1.1	3.1	0.8	0.4	0.5	1.8	0.9	1.4	0.9	1.1	0.9	0.9
Leg pain on walking	0.7	0.9	2.2	-1.3	-1.4	-1.5	0.5	-1.1	-1.3	-0.5	-0.4	-0.4	-0.2
Smoking status: Previous	0.7	1.0	2.3	-1.5	-0.7	-1.1	-0.3	-1.0	-1.4	-0.4	-0.9	-0.7	-1.1
Osteoporosis (self-reported)	0.7	0.8	1.8	0.4	0.4	1.0	1.1	0.9	0.4	1.2	1.0	1.3	0.8
Osteoarthritis (self-reported)	0.7	0.9	1.9	0.8	1.3	1.0	0.2	1.2	1.4	0.9	0.9	-0.1	0.8
Leg fat percentage (left)	0.7	2.5	8.1	-0.6	0.1	-0.8	-2.2	-0.9	-0.7	-0.9	-2.2	-2.8	-2.0
Number of operations (self-reported)	0.7	1.1	2.9	-0.5	-0.2	-1.1	-1.3	-0.9	-0.5	-0.9	-1.3	-1.7	-1.3
Diastolic blood pressure, automated reading	0.7	2.1	3.6	-0.5	-1.4	-1.4	-1.5	-1.4	-1.0	-1.6	-1.9	-1.7	-1.6
Pain experienced in last month	0.7	1.1	2.6	1.2	1.0	1.3	1.0	1.2	1.6	1.0	0.7	0.4	0.6
Alzheimer’s Disease (in mother)	0.6	0.7	1.7	-0.1	-0.2	-0.7	-1.3	-0.7	-0.5	-1.1	-1.0	-1.1	-0.7
Blood White Count	0.6	4.2	8.0	1.9	2.8	2.3	1.1	2.3	1.0	2.5	2.0	1.7	2.0
Hypothyroidism (self reported)	0.6	1.5	5.3	-2.3	-1.4	-1.0	-0.7	-1.1	-1.5	-0.8	-0.9	-0.2	-0.8
Respiratory disease	0.6	1.4	3.1	0.5	0.4	1.4	1.5	1.3	0.5	1.8	1.2	1.5	0.9
Systolic blood pressure, automated reading	0.6	1.8	2.5	-1.1	-1.5	-1.4	-1.2	-1.4	-1.2	-1.4	-1.6	-1.4	-1.3
Qualifications: CSEs or equivalent	0.6	0.8	1.3	0.5	0.8	1.0	0.8	0.9	0.0	1.1	1.0	1.1	0.9
Supplements: Glucosamine	0.6	0.8	1.6	-0.1	-0.0	0.9	1.2	0.9	1.3	0.8	1.0	0.6	1.1
Sitting height	0.6	4.0	8.4	0.6	0.3	1.9	2.6	1.8	0.7	2.0	2.5	2.9	2.6
Waist circumference	0.6	2.3	6.2	-1.2	-0.7	-1.0	-1.6	-1.0	-0.7	-0.9	-2.2	-2.5	-2.1
Qualifications: None of the above	0.6	1.3	3.0	-0.2	-0.0	-0.6	-1.7	-0.7	-0.8	-0.8	-1.6	-1.7	-1.4
Mouth/teeth dental problems	0.6	1.0	2.0	-1.0	-1.4	-1.0	0.7	-1.1	-0.9	-0.8	0.6	1.4	0.3
Qualifications: A levels/AS levels or equivalent	0.6	1.3	4.5	-1.7	-1.9	-0.7	-0.0	-1.0	-2.1	-0.4	-0.6	0.3	-0.2
Breastfed as a baby	0.6	0.8	1.8	-0.9	-1.4	-1.1	-0.1	-1.3	-0.5	-1.3	-0.4	-0.0	-0.7
Birth weight of first child	0.6	1.1	2.4	-0.9	-1.0	-1.2	-1.0	-1.2	-0.6	-1.6	-1.2	-0.9	-0.7
Irritability	0.6	1.0	3.4	0.6	-0.0	0.6	1.8	1.0	0.8	1.2	1.0	1.1	0.7
Age started oral contraceptive pill	0.6	0.7	2.2	-1.4	-1.5	-0.8	0.2	-0.6	-0.6	-0.4	-0.7	-0.4	-0.6
Neuroticism (Nagel 2018)	0.5	1.2	3.4	0.5	0.2	0.9	1.9	1.2	0.6	1.5	1.0	1.2	0.9
Coronary Artery Disease (CAD)	0.5	0.6	1.7	-0.4	-0.6	-0.3	-1.3	-0.6	-0.5	-0.9	-1.0	-0.8	-0.7
Type 2 Diabetes (T2D) (2012)	0.5	0.5	0.9	-0.9	-0.7	-0.7	-0.5	-0.8	-0.4	-0.8	-0.7	-0.9	-0.6
Systolic Blood Pressure	0.5	2.5	4.0	-0.8	-1.3	-2.0	-1.6	-1.8	-1.3	-1.7	-1.6	-1.7	-1.8
Chronotype (morning person)	0.5	1.1	3.4	1.8	1.5	1.0	-0.3	1.0	1.5	0.4	0.7	-0.2	0.5
Pack years adult smoking proportion	0.5	0.7	2.6	0.2	1.0	0.3	-1.6	0.4	0.3	-0.0	-0.9	-1.3	-0.7
High blood pressure	0.5	1.4	3.9	2.0	1.8	0.5	-0.4	0.9	1.8	0.5	-0.3	-1.2	-0.4
Chronic bronchitis/emphysema (father)	0.5	0.6	1.3	0.7	1.1	1.1	-0.4	1.0	0.7	0.6	0.3	0.3	0.6
Forced vital capacity (FVC)	0.5	1.7	2.8	1.2	0.4	1.5	1.6	1.3	0.7	1.4	1.4	1.7	1.5
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	0.9	-0.6	-0.9	-0.8	-0.6	-0.9	-1.0	-0.9	-0.9	-0.8	-0.6
Asthma	0.5	0.9	2.7	-0.7	-0.6	0.5	1.4	0.5	-0.6	1.0	1.1	1.7	0.9
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.3	0.0	0.5	0.4	1.0	0.5	0.5	0.5	1.1	1.1	1.1
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.0	0.3	0.1	0.9	0.8	0.8	0.4	0.7	0.7	1.0	1.0
Neck or shoulder pain in last month	0.5	0.6	1.5	-0.6	-0.8	-1.2	-0.7	-0.9	-1.1	-0.8	-0.4	-0.6	-0.5
Angina (self-reported)	0.5	0.7	2.1	-0.5	-0.4	-0.1	-1.4	-0.5	-0.4	-1.0	-1.1	-1.1	-0.8
Knee pain experienced in last month	0.5	0.7	2.3	-1.5	-1.4	-1.0	0.1	-0.8	-0.9	-0.7	-0.1	0.1	-0.2
Hypertension (Self-reported)	0.5	1.4	3.2	1.7	1.8	0.9	-0.4	1.1	1.8	0.8	-0.4	-1.3	-0.3
Illnesses of siblings: Diabetes	0.5	0.6	1.1	-0.4	-0.7	-0.5	-0.7	-0.8	-0.2	-0.9	-1.0	-0.8	-1.0
Mood swings	0.5	0.9	3.7	0.3	0.6	1.4	0.8	1.5	0.4	1.9	-0.0	-0.2	-0.1
Wears glasses or contact lenses	0.5	0.5	1.2	0.5	0.2	-0.9	-0.9	-0.7	0.2	-0.7	-0.7	-1.1	-0.9
Irritable Bowel Disease (IBD)	0.4	0.9	2.6	1.2	0.6	-0.2	0.7	0.2	0.8	0.1	1.6	1.3	1.2
Ulcerative Colitis (UC)	0.4	0.7	2.1	0.6	0.4	-0.2	0.7	0.2	0.2	0.3	1.5	1.4	1.4
Neuroticism (2016)	0.4	0.6	1.6	0.7	1.1	1.1	0.5	1.0	0.0	1.3	0.3	0.4	0.5
Frequency of depressed mood in last 2 weeks	0.4	0.5	0.9	0.7	0.2	0.9	0.7	0.9	0.4	0.8	0.5	0.8	0.8
Relative age of first facial hair	0.4	0.8	4.1	-0.4	-0.8	-1.2	-0.3	-1.0	-2.0	-0.5	-0.0	0.4	-0.2
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.1	-1.1	-0.8	-0.5	-0.3	-0.4	-0.8	-0.2	-0.8	-0.6	-0.8
Nervous feelings	0.4	0.8	2.0	-1.1	-1.4	-1.0	0.1	-0.9	-1.3	-0.4	-0.8	0.0	-0.6
Neuroticism score	0.4	0.7	2.5	-0.1	-0.2	0.6	1.6	0.9	0.2	1.4	0.8	0.9	0.6
Number of live births	0.4	0.5	1.1	0.8	1.1	0.9	0.3	1.0	0.9	0.7	0.5	-0.0	0.6
Mouth/teeth dental problems: Dentures	0.4	0.7	2.3	0.5	0.5	0.2	-1.5	0.3	-0.1	0.1	-1.0	-1.5	-0.6
Medication: Paracetamol	0.4	0.6	1.4	0.4	0.2	0.4	1.2	0.7	0.4	0.8	1.0	1.1	1.1
Medication: Amlodipine	0.4	0.5	2.2	0.5	1.0	0.5	-0.5	0.4	1.5	-0.2	-0.4	-0.8	-0.3
Wheeze or whistling in the chest in last year	0.4	0.7	2.4	-1.6	-1.4	-0.5	0.5	-0.4	-1.2	0.1	-0.3	0.5	-0.3
Leg fat mass (right)	0.4	1.4	5.4	-0.3	0.3	-0.2	-1.6	-0.3	-0.0	-0.5	-1.8	-2.3	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	1.4	0.2	1.2	0.4	-1.2	0.6	-0.7	0.6	-0.1	-0.5	0.3
Ever had bowel cancer screening	0.4	0.5	2.9	1.0	0.7	0.0	0.6	0.3	1.7	0.1	0.4	-0.0	0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	2.5	-1.6	-1.2	-0.2	-0.1	-0.4	-0.8	-0.4	-0.2	-0.0	0.0
Back pain experienced in last month	0.4	0.5	1.4	-0.7	-0.9	0.1	0.6	0.1	-1.2	0.6	0.6	1.0	0.8
Mineral and other dietary supplements	0.4	0.5	1.2	-0.0	-0.1	-0.8	-1.1	-0.8	-0.9	-0.9	-0.6	-0.3	-0.7
Breast cancer (self-reported)	0.4	0.4	1.4	-0.5	-1.2	-0.9	0.3	-0.8	-0.6	-0.8	-0.2	0.4	0.1
Asthma (self-reported)	0.4	0.9	2.3	-0.8	-0.6	0.5	1.3	0.5	-0.5	1.1	1.0	1.5	0.8
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.0	-0.7	-0.2	-0.8	-0.9	-0.7	-1.0	-0.5	-0.7	-0.5	-0.6
Vascular/heart problems diagnosed by doctor	0.4	1.1	2.3	-1.5	-1.4	-0.2	0.8	-0.5	-1.5	-0.0	0.7	1.5	0.7
Basal cell carcinoma (self-reported)	0.4	0.5	1.4	-0.4	0.3	1.2	0.7	0.9	0.4	0.9	0.6	0.6	0.7
Pack years of smoking	0.4	0.6	2.3	0.4	1.1	0.3	-1.5	0.5	0.2	0.1	-0.7	-1.2	-0.5
Crohns Disease (2017)	0.3	0.7	2.4	1.6	0.9	0.1	0.2	0.2	1.2	-0.0	1.1	0.7	0.6
Major Depression (MDD)	0.3	0.4	1.1	-1.0	-0.9	-0.5	0.1	-0.6	-0.8	-0.5	-0.0	0.5	-0.1
Ovarian Cancer	0.3	0.4	0.9	-0.5	-0.3	-0.8	-0.3	-0.6	-0.1	-0.6	-0.6	-0.9	-0.9
Age at First Birth	0.3	0.4	1.2	-1.0	-1.1	-0.4	-0.1	-0.7	-0.9	-0.6	-0.0	0.6	-0.0
LDL Cholesterol	0.3	0.4	2.2	-1.0	-0.5	0.4	-0.2	0.0	-1.5	0.3	-0.2	0.3	0.2
Rheumatoid Arthritis	0.3	0.4	0.7	0.6	0.3	0.5	0.5	0.8	0.8	0.5	0.8	0.4	0.7
Waist Hip Ratio (WHR)	0.3	1.5	3.1	-0.5	-0.8	-1.3	-1.4	-1.1	-1.0	-0.8	-1.4	-1.7	-1.8
Hand grip strength (left)	0.3	0.8	1.3	1.1	0.8	0.9	0.6	1.0	0.5	0.9	1.1	0.9	1.1
Vitamin and mineral supplements	0.3	0.4	0.8	-0.4	-0.6	-0.3	-0.6	-0.3	0.4	-0.9	-0.9	-0.9	-0.6
Fed-up feelings	0.3	0.5	1.7	0.1	0.1	0.5	1.3	0.7	0.0	1.3	0.6	0.7	0.3
Body mass index (BMI)	0.3	1.4	4.2	-0.9	-0.3	-0.4	-1.5	-0.5	-0.5	-0.6	-1.8	-2.0	-1.6
Hair/balding pattern: Pattern 2	0.3	0.3	1.2	0.2	1.1	1.0	-0.1	0.7	0.4	0.7	0.1	0.1	0.2
Pain all over the body in last month	0.3	0.3	1.7	-0.1	0.9	0.7	-1.3	0.2	-0.1	-0.1	-0.4	-0.4	0.2
Arm fat percentage (right)	0.3	1.1	4.7	0.2	0.3	-0.1	-1.3	-0.1	0.3	-0.3	-1.6	-2.2	-1.4
Worrier / anxious feelings	0.3	0.7	1.4	0.7	0.5	0.2	1.2	0.7	0.8	0.8	1.1	0.8	0.9
Happiness	0.3	0.4	1.3	0.1	-0.4	0.6	0.5	0.6	-0.2	0.3	0.7	1.0	1.1
Length of working week for main job	0.3	0.3	0.8	0.7	0.9	0.4	-0.9	0.3	-0.7	0.4	-0.3	-0.3	0.1
Headache pain in last month	0.3	0.5	2.0	-0.9	-1.0	-0.4	-0.4	-0.4	-1.4	-0.2	-0.6	-0.2	-0.4
Forced vital capacity (FVC), Best measure	0.3	1.1	3.0	0.5	-0.5	1.1	1.4	0.8	-0.1	0.9	1.0	1.7	1.4
Medication: Omeprazole	0.3	0.4	2.0	-0.0	0.5	0.2	-1.4	0.0	-0.3	-0.2	-0.7	-0.9	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.8	0.3	0.9	0.5	0.3	0.5	0.9	0.3	0.7	0.9	0.7
Overall health rating	0.3	0.6	1.6	0.6	1.1	1.0	0.5	1.2	0.5	1.2	0.1	0.1	0.3
Had major operations	0.3	0.4	0.8	-0.3	-0.7	-0.6	-0.6	-0.6	-0.3	-0.9	-0.6	-0.8	-0.5
Average weekly red wine intake	0.3	0.4	0.8	-0.3	-0.5	-0.9	-0.8	-0.8	-0.7	-0.6	-0.7	-0.4	-0.6
Loneliness, isolation	0.3	0.4	1.2	0.0	0.0	0.4	1.1	0.6	-0.4	1.1	0.6	0.8	0.5
Eye problems/disorders: Cataract	0.3	0.3	0.9	0.7	0.6	0.7	0.0	0.8	0.1	1.0	-0.2	-0.5	0.2
Hearing aid user	0.3	0.3	0.7	0.2	-0.8	-0.9	0.9	-0.4	-0.0	-0.3	0.3	0.5	0.3
Medication: Atorvastatin	0.3	0.3	1.2	0.3	0.2	0.8	0.7	0.8	0.3	1.1	0.2	0.2	0.0
Ever smoked	0.3	0.5	1.1	0.5	0.8	0.6	1.1	0.7	0.5	1.0	0.5	0.5	0.2
Fractured/broken bones in last 5 years	0.3	0.4	1.1	0.3	0.0	0.1	-0.7	-0.0	0.2	-0.1	-1.1	-0.9	-1.0
Alcohol drinker status: Previous	0.3	0.3	0.8	0.0	0.5	0.9	0.4	0.9	0.6	0.8	0.2	0.2	0.5
Leg fat mass (left)	0.3	1.1	4.4	-0.2	0.5	0.1	-1.4	0.0	0.2	-0.2	-1.5	-2.1	-1.3
HbA1C	0.2	0.2	0.5	0.1	-0.6	0.7	0.6	0.6	-0.1	0.7	-0.1	-0.2	0.2
Lupus	0.2	0.3	1.0	0.4	-0.5	-1.0	0.3	-0.5	0.6	-0.6	-0.2	-0.3	-0.5
Lung FEV1/FVC ratio	0.2	0.8	2.9	0.0	0.4	0.4	-1.7	-0.1	-0.4	-0.4	-1.3	-1.5	-0.7
Neuroticism	0.2	0.5	2.5	-0.2	-0.6	0.0	1.6	0.3	0.1	0.7	0.7	0.9	0.4
Tanning	0.2	3.0	4.5	2.0	1.7	1.7	1.2	1.8	0.9	1.8	2.1	1.7	2.1
Number of treatments/medications taken	0.2	0.4	1.5	-0.0	0.3	-0.2	-0.5	-0.1	0.1	0.0	-1.0	-1.2	-0.8
Average weekly spirits intake	0.2	0.2	0.5	-0.2	-0.0	0.4	0.7	0.4	-0.3	0.6	0.3	0.5	0.6
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.3	-1.1	-1.1	0.2	0.2	-0.1	-0.4	0.0	-0.3	-0.1	-0.2
Ever had hysterectomy (womb removed)	0.2	0.2	1.1	0.4	1.0	0.2	-0.2	0.4	-0.1	0.7	0.0	-0.4	-0.1
Hand grip strength (right)	0.2	0.5	1.0	0.2	0.3	0.8	0.4	0.7	-0.1	0.7	0.9	1.0	1.0
Average weekly fortified wine intake	0.2	0.2	0.9	-0.0	1.0	0.2	-0.1	0.4	0.8	0.0	0.3	-0.0	0.5
Maternal smoking around birth	0.2	0.4	0.8	0.3	0.6	0.2	0.9	0.6	0.6	0.8	0.6	0.3	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.7	0.2	-0.8	-0.4	-0.1	-0.5	-0.8	-0.2	-0.6	-0.2	-0.5
Taking other prescription medications	0.2	0.3	0.6	-0.7	-0.8	-0.8	0.1	-0.5	-0.1	-0.5	-0.5	-0.3	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.7	-0.4	-0.9	0.3	1.2	0.2	-0.2	0.2	0.7	1.3	0.8
Serious illness, injury or assault to yourself	0.2	0.2	0.8	-0.1	-0.9	-0.3	0.5	-0.5	-0.6	-0.3	-0.5	0.4	-0.5
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.0	-0.4	-0.7	-0.5	0.0	-0.4	-1.0	-0.3	-0.2	0.1	-0.1
Medication: Simvastatin	0.2	0.3	1.0	0.4	0.6	0.3	1.0	0.4	0.9	0.6	0.4	-0.0	0.4
Impedance of arm (right)	0.2	1.2	3.5	1.9	1.1	0.7	0.6	1.1	1.3	0.6	1.2	0.7	1.0
Father’s age at death	0.2	0.2	0.6	-0.6	-0.0	-0.3	-0.8	-0.1	0.3	-0.4	-0.4	-0.8	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.2	0.3	-0.5	0.3	0.3	0.3	-1.1	0.6	0.3	0.5	0.6
Medication: Lansoprazole	0.2	0.2	0.7	0.3	0.4	0.3	0.1	0.3	0.1	0.2	0.7	0.7	0.8
Pulse wave Arterial Stiffness index	0.2	0.2	0.9	0.1	-0.1	-0.6	-0.1	-0.7	0.3	-0.9	0.0	0.1	-0.2
Impedance of arm (left)	0.2	1.1	2.8	1.7	0.7	0.6	0.8	0.9	1.2	0.6	1.4	1.0	1.0
Standing height	0.2	2.2	5.0	0.3	0.1	1.2	2.2	1.2	0.5	1.6	1.9	2.0	1.8
Peak expiratory flow (PEF)	0.2	0.4	0.7	0.1	0.8	0.7	0.5	0.6	0.2	0.8	0.6	0.7	0.6
Body fat percentage	0.2	0.7	3.5	0.1	0.5	-0.1	-0.9	0.1	0.3	-0.0	-1.2	-1.9	-1.2
Number of full brothers	0.2	0.2	0.6	0.2	0.3	-0.2	0.8	-0.1	-0.3	0.4	0.6	0.7	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.6	0.1	0.7	0.4	-0.3	0.4	0.5	0.3	-0.4	-0.8	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.5	-0.4	-0.5	-0.1	0.5	-0.0	0.1	-0.2	0.7	0.6	0.7
Age at first live birth	0.2	0.4	1.4	0.3	-0.9	-0.1	0.9	-0.0	1.2	-0.5	0.5	0.6	0.2
Eye problems/disorders: None of the above	0.2	0.3	0.7	0.4	0.6	0.8	-0.3	0.6	0.1	0.2	0.5	0.5	0.7
Comparative height size at age 10	0.2	1.1	2.0	0.4	0.8	1.0	1.4	1.2	1.2	1.2	1.1	0.7	0.9
Age at last live birth	0.2	0.3	1.0	-0.1	-1.0	-0.4	0.9	-0.3	0.0	-0.3	0.4	0.8	0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.8	0.1	-0.0	0.5	-0.3	0.4	-0.9	0.7	-0.1	-0.1	0.3
Medication: Aspirin	0.2	0.2	0.9	0.3	0.5	-0.0	-0.3	-0.1	-0.1	-0.0	-0.7	-0.9	-0.5
Supplements: Vitamin C	0.2	0.2	0.9	-0.6	0.1	-0.9	0.3	-0.8	-0.4	-0.2	0.2	0.1	-0.4
Leg fat-free mass (right)	0.2	1.0	2.2	-0.0	0.3	1.5	1.4	1.2	0.8	1.4	0.7	0.9	0.8
Arm fat percentage (left)	0.2	0.7	3.2	0.2	0.2	0.0	-0.9	0.0	0.5	-0.2	-1.3	-1.8	-1.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.0	0.4	0.6	0.2	0.4	0.2	1.0	0.0	0.2	0.2	-0.1
Qualifications: nursing, teaching	0.2	0.3	1.4	0.4	0.4	-0.1	-0.2	-0.1	1.2	-0.5	-0.6	-0.9	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.8	0.2	0.8	0.9	-0.2	0.8	0.1	0.7	-0.2	-0.4	0.4
Medication: Aspirin	0.2	0.2	0.9	-0.0	0.3	-0.2	-0.5	-0.3	-0.2	-0.2	-0.7	-0.9	-0.5
Leg predicted mass (right)	0.2	1.1	2.2	0.0	0.3	1.5	1.4	1.3	0.8	1.5	0.8	0.9	0.8
Number of self-reported non-cancer illnesses	0.2	0.3	0.9	0.2	0.4	0.2	-0.7	0.4	0.2	0.4	-0.6	-0.9	-0.5
Mother’s age at death	0.2	0.2	0.7	-0.4	-0.2	-0.8	-0.2	-0.5	0.3	-0.8	-0.3	-0.3	-0.1
Eye problems/disorders: Glaucoma	0.2	0.2	0.4	-0.3	-0.3	-0.6	-0.4	-0.5	-0.2	-0.5	-0.7	-0.7	-0.5
Medication: Blood pressure	0.2	0.5	1.2	1.1	0.3	0.4	0.7	0.6	0.3	0.8	0.9	0.7	0.6
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.0	-0.8	-1.0	-0.8	0.6	-0.6	-0.2	-0.2	0.0	-0.1	-0.2
Medication: Paracetamol	0.2	0.3	1.0	0.1	-0.1	-0.1	1.0	0.3	0.4	0.3	0.6	0.9	0.6
Medication: Lisinopril	0.2	0.2	1.5	-1.2	-0.5	0.0	0.6	0.1	-0.2	0.2	-0.3	0.1	-0.2
Risk taking	0.2	0.2	0.6	-0.4	-0.7	-0.3	-0.3	-0.3	0.1	-0.4	-0.6	-0.8	-0.7
Ever depressed for a whole week	0.2	0.3	0.8	0.3	-0.1	0.1	0.8	0.3	-0.3	0.3	0.6	0.8	0.9
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.9	0.0	1.0	0.5	-0.8	0.4	-0.0	0.3	-0.4	-0.6	-0.2
Bipolar Disorder or Schizophrenia	0.1	0.3	0.7	0.1	0.5	0.0	-0.0	0.3	-0.7	0.6	0.8	0.8	0.7
Depression (Nagel 2018)	0.1	0.2	0.6	0.2	0.1	0.4	0.6	0.3	-0.3	0.7	0.1	0.8	0.4
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.9	-0.4	-1.4	0.1	0.8	-0.1	0.1	-0.0	-0.3	-0.2	-0.4
Worry (Nagel 2018)	0.1	0.2	1.0	0.2	-0.6	-0.2	1.0	0.1	0.4	0.1	0.2	0.5	0.2
Reaction Time	0.1	0.2	0.9	0.2	0.5	0.0	1.0	0.1	0.1	0.5	0.1	0.2	-0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.7	-0.4	-0.8	0.2	0.5	0.2	0.5	0.0	0.2	0.1	0.2
Body Mass Index (BMI) (2010)	0.1	0.2	0.5	0.4	0.7	0.4	-0.1	0.5	0.7	0.4	0.1	-0.3	-0.2
Crohns Disease (2012)	0.1	0.2	0.7	0.9	-0.0	0.3	-0.1	0.2	0.6	-0.2	0.4	0.4	0.6
Fasting Glucose	0.1	0.2	0.4	-0.2	-0.2	-0.6	-0.0	-0.5	-0.2	-0.4	0.6	0.5	0.2
HDL Cholesterol	0.1	0.1	0.4	-0.1	-0.1	-0.1	-0.7	-0.1	-0.1	-0.3	-0.4	-0.5	-0.4
Schizophrenia (2014)	0.1	0.3	1.0	0.5	1.0	-0.0	0.0	0.2	-0.2	0.5	0.8	0.5	0.6
Heel T-Score	0.1	0.6	1.7	0.7	-0.8	-1.1	-0.2	-1.1	-0.1	-1.3	-0.4	-0.3	-0.0
BMI	0.1	0.4	1.0	-0.0	0.8	0.6	-0.6	0.4	0.1	0.5	-0.8	-1.0	-0.6
Cardiovascular Disease	0.1	0.4	0.9	0.9	0.9	0.7	-0.3	0.8	0.6	0.7	-0.2	-0.7	0.0
Hair Pigment	0.1	1.9	6.5	1.3	2.5	1.3	0.4	1.5	1.5	1.5	1.1	0.1	0.9
Sensitivity / hurt feelings	0.1	0.1	0.5	-0.7	-0.4	-0.1	0.1	0.0	-0.3	0.2	-0.4	-0.6	-0.4
Medication for hormone replacement therapy	0.1	0.1	0.4	0.0	0.5	0.2	-0.3	0.1	0.1	0.1	-0.2	-0.6	-0.1
Diabetes (father)	0.1	0.2	0.5	0.5	0.0	0.6	-0.1	0.5	0.0	0.3	0.4	0.4	0.7
Impedance of leg (right)	0.1	0.3	1.1	0.6	0.6	-0.7	-1.0	-0.4	-0.4	-0.5	-0.3	-0.7	-0.2
Leg fat-free mass (left)	0.1	0.6	1.4	-0.0	0.2	1.2	1.0	1.0	0.6	1.1	0.5	0.6	0.5
Trunk fat percentage	0.1	0.4	1.6	0.3	0.6	0.5	-0.4	0.6	0.6	0.5	-0.6	-1.3	-0.6
Age when periods started (menarche)	0.1	0.2	1.2	1.1	0.7	0.0	0.2	0.2	0.1	0.3	0.2	0.0	0.2
Leg predicted mass (left)	0.1	0.5	1.3	-0.1	0.2	1.1	1.0	0.9	0.6	1.0	0.4	0.6	0.5
Trunk fat mass	0.1	0.3	1.2	0.1	0.4	0.6	-0.1	0.6	0.5	0.6	-0.6	-1.1	-0.5
Past tobacco smoking	0.1	0.2	0.4	0.6	0.1	0.5	-0.6	0.3	0.6	-0.3	0.1	-0.1	0.4
Had menopause	0.1	0.1	0.4	-0.2	0.2	-0.2	-0.2	0.1	-0.7	0.4	0.0	0.2	0.3
Fluid intelligence score	0.1	0.3	1.4	-0.1	-0.5	0.4	0.7	0.5	1.2	0.1	0.2	-0.1	0.1
Weight	0.1	0.3	0.9	-0.7	-0.2	0.2	-0.2	0.1	-0.2	0.2	-0.8	-0.9	-0.7
Trunk fat-free mass	0.1	0.3	1.1	-1.1	-0.4	0.6	0.7	0.3	-0.5	0.7	-0.0	0.4	0.3
Hip circumference	0.1	0.6	1.9	-0.6	-0.2	-0.2	-0.8	-0.3	-0.2	-0.4	-1.3	-1.4	-1.0
Alcohol intake versus 10 years previously	0.1	0.1	0.4	0.6	-0.1	0.4	0.3	0.5	0.1	0.5	0.0	-0.0	-0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.4	0.6	0.2	1.2	0.5	0.7	0.3	0.6	0.4	0.7	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.4	0.1	0.3	0.4	0.6	0.3	0.1	0.4	-0.0	0.3	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.5	1.2	0.0	-0.6	1.0	0.7	0.5	-0.4	0.5	0.4	1.1	0.9
Arm fat mass (right)	0.1	0.6	2.5	-0.1	0.2	0.3	-0.8	0.2	0.1	0.1	-1.2	-1.6	-1.0
Trunk predicted mass	0.1	0.3	1.0	-1.0	-0.4	0.5	0.7	0.3	-0.5	0.7	-0.0	0.4	0.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.5	-0.1	-0.4	0.1	-0.0	0.1	0.5	-0.2	-0.4	-0.7	-0.5
Glaucoma (self-reported)	0.1	0.1	0.4	0.1	0.0	-0.2	0.6	-0.1	0.4	0.1	0.0	-0.1	-0.3
High blood pressure (siblings)	0.1	0.2	0.9	0.9	0.5	0.6	0.3	0.4	0.1	0.6	-0.2	0.1	0.2
Arm fat-free mass (right)	0.1	0.3	0.9	-0.9	-0.2	0.7	0.8	0.5	-0.2	0.9	0.1	0.3	0.3
Exposure to tobacco smoke outside home	0.1	0.1	0.4	0.1	-0.1	0.0	0.7	0.1	0.5	0.1	0.2	0.4	0.2
Worry too long after embarrassment	0.1	0.2	0.5	-0.7	-0.4	-0.4	0.6	-0.1	-0.3	0.3	0.3	0.2	-0.2
Pulse wave peak to peak time	0.1	0.2	0.7	-0.0	0.1	0.5	0.1	0.7	-0.1	0.8	-0.0	-0.3	0.1
Health satisfaction	0.1	0.2	0.4	-0.3	-0.4	-0.4	0.0	-0.3	-0.2	-0.6	0.3	0.4	0.6
Shortness of breath walking on level ground	0.1	0.1	0.4	-0.4	0.6	0.2	-0.0	0.4	0.0	0.4	0.1	-0.2	0.1
Qualifications: College or University degree	0.1	0.3	1.0	-0.8	-1.0	-0.1	0.7	0.0	-0.6	0.4	0.3	0.7	0.3
Mean time to correctly identify matches	0.1	0.2	0.7	0.1	0.7	-0.2	0.3	-0.1	0.5	0.2	-0.5	-0.6	-0.8
Heart disease (mother)	0.1	0.2	0.6	-0.3	0.2	-0.3	-0.5	-0.2	-0.1	-0.2	-0.8	-0.7	-0.4
Whole body fat mass	0.1	0.4	1.9	0.0	0.5	0.4	-0.4	0.4	0.5	0.4	-0.8	-1.4	-0.8
Arm predicted mass (right)	0.1	0.6	1.5	-0.6	0.0	1.0	1.0	0.7	-0.2	1.2	0.4	0.7	0.6
Family relationship satisfaction	0.1	0.1	0.4	0.3	0.6	-0.1	-0.5	-0.0	0.7	-0.6	-0.0	-0.3	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.5	0.7	0.3	-0.3	0.2	-0.4	0.6	-0.5	0.1	-0.3	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	1.4	-1.2	-0.8	0.3	0.4	-0.0	-0.8	0.1	-0.2	0.3	0.1
Whole body fat-free mass	0.1	0.3	0.9	-0.6	-0.1	0.9	0.8	0.6	0.0	0.9	0.1	0.4	0.4
Long-standing illness, disability or infirmity	0.1	0.2	0.5	-0.7	-0.3	-0.2	-0.2	-0.2	-0.3	-0.0	-0.7	-0.5	-0.5
Friendships satisfaction	0.1	0.2	0.5	0.6	0.2	-0.2	0.4	0.3	0.7	-0.1	0.5	-0.1	0.4
Commuting to job workplace: Walk	0.1	0.1	0.5	0.2	0.4	0.4	-0.5	0.3	0.3	0.2	-0.3	-0.7	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.6	0.8	0.3	0.0	-0.3	0.0	-0.0	-0.1	0.4	0.4	0.5
Arm fat mass (left)	0.1	0.5	2.0	-0.1	0.2	0.3	-0.7	0.2	0.1	0.1	-1.1	-1.4	-0.9
Average weekly champagne plus white wine intake	0.1	0.1	0.7	-0.2	-0.0	-0.4	0.8	-0.2	-0.4	0.4	0.2	0.3	0.0
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.3	0.1	-0.6	-0.4	0.4	-0.6	-0.4	-0.2	-0.1	0.1	-0.2
Commuting to job workplace: Public transport	0.1	0.1	0.5	0.5	-0.2	-0.2	0.7	-0.3	0.5	-0.2	0.3	0.4	-0.1
High cholesterol (Self-reported)	0.1	0.2	0.6	-0.8	-0.3	0.3	0.5	0.2	-0.3	0.6	-0.2	-0.2	-0.1
Commuting to job workplace: Cycle	0.1	0.1	0.6	0.4	0.4	0.2	0.1	0.2	0.8	-0.2	0.1	0.1	0.3
Impedance of whole body	0.1	0.5	2.0	1.4	0.8	0.3	0.2	0.6	0.6	0.4	0.9	0.4	0.7
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Height	0.0	0.5	1.2	0.1	0.4	0.4	1.1	0.7	0.4	1.0	1.1	0.7	0.7
Smoking Status	0.0	0.1	0.2	0.0	0.2	0.2	0.0	0.1	-0.3	0.4	-0.2	-0.3	-0.5
Lung FVC	0.0	0.1	0.4	0.1	-0.6	-0.3	0.2	-0.4	0.1	-0.5	-0.3	-0.0	-0.2
Diabetes (mother)	0.0	0.0	0.1	-0.2	-0.1	0.2	-0.3	0.3	-0.1	0.1	-0.1	-0.4	0.2
Impedance of leg (left)	0.0	0.2	0.9	0.8	0.9	0.1	-0.5	0.3	-0.1	0.3	0.2	-0.2	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.2	-0.1	-0.3	0.1	0.4	0.2	-0.1	0.2	-0.1	0.3	0.0
Time employed in main current job	0.0	0.0	0.1	0.1	0.0	-0.2	-0.1	-0.2	0.1	-0.3	-0.4	-0.2	-0.3
Alcohol intake frequency.	0.0	0.1	0.1	-0.3	-0.3	-0.2	0.2	-0.2	-0.3	0.0	-0.3	-0.1	-0.2
Medication for cholesterol	0.0	0.1	0.2	0.3	0.2	-0.4	-0.2	-0.2	0.4	-0.4	0.0	-0.1	-0.1
Whole body water mass	0.0	0.3	0.7	-0.7	-0.2	0.7	0.8	0.5	0.0	0.8	0.0	0.3	0.2
Illnesses of father: High blood pressure	0.0	0.0	0.2	0.5	-0.2	0.1	-0.1	-0.0	-0.2	-0.3	0.1	0.1	0.2
Basal metabolic rate	0.0	0.3	0.7	-0.6	-0.1	0.8	0.7	0.6	0.0	0.9	0.0	0.2	0.3
Arm fat-free mass (left)	0.0	0.2	1.0	-1.0	-0.4	0.3	0.6	0.2	-0.5	0.6	-0.3	0.1	0.0
Arm predicted mass (left)	0.0	0.2	0.9	-0.9	-0.5	0.0	0.2	-0.1	-0.7	0.3	-0.6	-0.3	-0.3

Hub : Genes

KLRC1

Models

Trait associations