TWAS hub - KLRC2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.6040	0.0360	0.0e+00	0.506	0.606	0.658	0.634	0.656	4.3e-71	2.6e-93	5.4e-107	2.2e-100	1.8e-106
2	ROSMAP	Brain Pre-frontal Cortex	0.6156	0.0346	0.0e+00	0.470	0.611	0.619	0.627	0.623	6.2e-68	3.4e-100	2.7e-102	1.8e-104	2.8e-103
3	TCGA	Bladder Urothelial Carcinoma	0.1200	0.0530	1.6e-08	0.075	0.108	0.119	NA	0.094	6.4e-07	1.9e-09	2.8e-10	NA	2.3e-08
4	TCGA	Breast Invasive Carcinoma	0.0556	0.0233	3.7e-15	0.088	0.079	0.083	NA	0.088	1.3e-17	7.7e-16	1.2e-16	NA	2.0e-17
5	TCGA	Cervical Squamous Cell Carcinoma	0.0750	0.0410	8.2e-04	0.064	0.049	0.058	NA	0.048	4.2e-04	1.9e-03	8.0e-04	NA	2.1e-03
6	TCGA	Colon Adenocarcinoma	0.1050	0.0530	6.7e-05	0.073	0.086	0.059	NA	0.072	5.1e-05	1.1e-05	2.6e-04	NA	5.6e-05
7	TCGA	Glioblastoma Multiforme	0.2110	0.0910	1.8e-05	0.058	0.175	0.175	NA	0.146	7.7e-03	5.5e-06	5.5e-06	NA	3.4e-05
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0852	0.0449	6.4e-08	0.057	0.066	0.060	NA	0.062	5.0e-07	7.2e-08	2.4e-07	NA	1.7e-07
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.1300	0.0517	2.2e-12	0.055	0.114	0.107	NA	0.099	8.0e-07	8.5e-13	5.3e-12	NA	3.2e-11
10	TCGA	Brain Lower Grade Glioma	0.2194	0.0636	0.0e+00	0.292	0.324	0.316	NA	0.318	1.9e-33	1.1e-37	1.6e-36	NA	8.4e-37
11	TCGA	Liver Hepatocellular Carcinoma	0.0660	0.0420	5.1e-03	0.045	0.030	0.026	NA	0.033	3.6e-03	1.4e-02	2.0e-02	NA	1.1e-02
12	TCGA	Lung Adenocarcinoma	0.1049	0.0430	7.8e-16	0.141	0.141	0.138	NA	0.141	3.6e-16	3.7e-16	6.9e-16	NA	4.0e-16
13	TCGA	Lung Squamous Cell Carcinoma	0.0698	0.0338	1.0e-06	0.032	0.064	0.064	NA	0.064	1.2e-04	9.2e-08	8.2e-08	NA	8.1e-08
14	TCGA	Pancreatic Adenocarcinoma	0.0920	0.0520	7.1e-04	0.102	0.067	0.046	NA	0.092	4.9e-05	8.8e-04	5.4e-03	NA	1.1e-04
15	TCGA	Prostate Adenocarcinoma	0.0827	0.0414	3.4e-06	0.043	0.066	0.027	NA	0.053	2.6e-05	2.0e-07	7.3e-04	NA	3.1e-06
16	TCGA	Rectum Adenocarcinoma	0.3100	0.1290	2.5e-05	0.232	0.199	0.220	NA	0.217	3.7e-06	2.1e-05	6.8e-06	NA	7.8e-06
17	TCGA	Stomach Adenocarcinoma	0.1220	0.0560	3.4e-08	0.102	0.099	0.063	NA	0.094	7.6e-08	1.2e-07	2.6e-05	NA	2.6e-07
18	TCGA	Thyroid Carcinoma	0.0480	0.0270	6.7e-05	0.055	0.034	0.043	NA	0.039	4.4e-06	2.8e-04	5.1e-05	NA	9.9e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Pulse wave reflection index	5.1	6.3	8.9	-1.5	-1.4	-2.4	-2.9	-3.0	-2.6	-2.1	-2.6	-2.1	-2.6	-2.7	-2.9	-2.2	-2.4	-2.5	-2.9	-2.8	-2.8
Relative age voice broke	4.5	6.9	10.0	-2.2	-2.2	-3.0	-2.5	-2.4	-3.2	-1.7	-2.9	-3.1	-2.8	-2.6	-3.0	-3.0	-0.8	-3.0	-2.4	-2.7	-2.5
Tinnitus: Yes, but not now, but have in the past	4.5	4.8	7.3	-1.4	-1.5	-2.2	-2.4	-2.5	-2.0	-2.0	-2.3	-1.5	-2.1	-2.3	-2.4	-2.1	-2.3	-2.3	-2.4	-2.7	-2.5
Mouth/teeth dental problems	3.7	5.6	9.4	-2.7	-2.5	-1.9	-2.6	-2.6	-2.4	-3.1	-1.9	-2.5	-3.0	-2.5	-2.3	-1.3	-1.1	-2.6	-2.3	-2.0	-2.6
Medication: Blood pressure	3.0	5.2	7.0	2.2	2.2	2.6	2.2	2.3	2.5	2.0	2.4	2.5	2.5	2.2	2.4	2.2	1.0	2.6	2.2	2.3	2.2
Ever taken oral contraceptive pill	2.8	3.1	7.3	2.7	2.7	1.6	1.8	1.6	1.6	2.4	1.1	2.1	2.2	1.7	1.2	0.7	0.2	2.0	1.2	1.2	1.7
Ever used hormone-replacement therapy (HRT)	2.7	3.5	6.3	0.9	0.9	1.3	2.4	2.3	1.7	1.6	1.9	1.0	1.8	2.2	2.0	1.4	2.2	1.6	2.1	2.2	2.5
Hypertension (Self-reported)	2.7	7.5	10.4	2.8	2.8	2.6	2.7	2.9	3.0	3.0	2.6	3.1	3.2	2.6	2.9	1.9	1.1	3.2	2.7	2.6	2.8
Gout (self-reported)	2.5	3.4	5.8	2.2	2.4	2.1	1.8	1.5	2.1	1.6	1.7	2.4	2.1	1.9	1.7	1.8	-0.3	2.0	1.4	1.4	1.7
Heart attack/myocardial infarction (self-reported)	2.5	3.3	5.4	0.3	0.6	1.7	2.0	1.9	2.0	0.6	2.2	1.1	1.5	2.1	2.1	2.1	2.3	1.4	2.2	2.2	2.0
High blood pressure (mother)	2.4	3.3	5.4	1.9	1.8	2.1	1.5	1.6	2.0	1.8	1.8	2.3	2.1	1.6	2.0	1.8	0.4	2.3	1.5	1.7	1.5
Number of full sisters	2.4	2.9	4.3	1.1	1.1	1.4	2.1	2.0	1.9	1.4	1.8	1.3	1.7	2.0	1.9	1.4	1.6	1.6	1.9	1.9	2.0
Mood swings	2.4	4.4	14.4	3.1	3.0	0.7	2.5	2.3	1.6	3.8	0.8	1.9	2.8	2.2	1.3	-0.5	0.5	1.8	1.6	1.1	2.5
Alcohol drinker status: Never	2.4	2.8	6.1	-2.2	-2.2	-1.5	-1.8	-1.7	-1.5	-2.5	-1.2	-1.9	-2.1	-1.4	-1.5	-0.7	-0.4	-2.1	-1.3	-1.4	-1.6
Bilateral oophorectomy (both ovaries removed)	2.3	2.6	6.3	0.0	-0.2	1.3	1.8	1.9	1.6	0.7	2.0	0.7	1.2	1.7	2.0	1.7	2.5	1.3	2.0	2.1	1.9
Ulcerative Colitis	2.2	3.2	6.0	-1.1	-1.0	-1.0	-2.4	-2.2	-1.6	-2.0	-1.5	-1.1	-1.8	-2.1	-1.8	-0.8	-2.2	-1.6	-2.0	-1.9	-2.5
Heart attack	2.2	2.8	5.0	0.2	0.5	1.5	1.9	1.8	1.9	0.5	2.1	1.0	1.4	2.0	1.9	2.0	2.2	1.3	2.0	2.0	1.9
Medication: Co-codamol	2.1	2.4	5.6	2.1	2.4	2.1	1.0	1.0	1.6	1.5	1.3	2.3	1.7	1.0	1.3	1.5	-0.7	2.1	0.9	1.1	0.9
Pack years adult smoking proportion	2.1	3.2	4.3	1.5	1.4	1.8	2.0	2.0	2.1	1.5	1.8	2.0	2.0	2.0	1.9	1.4	0.9	1.9	1.9	1.7	2.0
High blood pressure	2.1	5.8	9.3	2.4	2.3	2.3	2.4	2.5	2.6	2.6	2.4	2.7	2.8	2.2	2.7	1.8	1.1	3.0	2.3	2.4	2.5
Medication: Amlodipine	2.1	2.9	4.7	1.2	1.3	2.2	1.5	1.6	2.1	1.0	2.0	1.9	1.7	1.6	2.0	2.0	0.9	2.0	1.7	1.9	1.6
Type 2 Diabetes (T2D) (2018)	2.0	3.8	7.8	2.8	2.8	1.4	1.9	2.0	2.0	2.7	1.1	2.5	2.5	1.9	1.4	0.3	0.0	2.1	1.5	1.0	1.9
Depression (self-reported)	2.0	2.4	6.7	2.3	2.2	0.9	1.7	1.5	1.3	2.6	0.8	1.6	1.9	1.5	1.1	0.3	0.1	1.7	1.1	1.0	1.6
Vascular/heart problems diagnosed by doctor	2.0	5.3	8.0	-1.9	-1.9	-2.4	-2.2	-2.4	-2.6	-2.0	-2.5	-2.5	-2.5	-2.2	-2.7	-2.0	-1.4	-2.8	-2.4	-2.4	-2.4
Relative age of first facial hair	1.9	4.0	6.0	-1.8	-1.9	-2.4	-1.9	-1.8	-2.4	-1.5	-2.1	-2.4	-2.2	-2.0	-2.2	-2.1	-0.4	-2.2	-1.9	-1.9	-1.8
Diabetes diagnosed by doctor	1.9	3.2	5.8	2.2	2.4	1.7	1.7	1.7	2.0	1.9	1.4	2.4	2.2	1.8	1.5	1.1	0.2	2.1	1.5	1.2	1.7
Fractured/broken bones in last 5 years	1.9	2.5	3.5	1.3	1.6	1.5	1.8	1.9	1.7	1.5	1.5	1.4	1.8	1.8	1.6	1.0	1.1	1.3	1.9	1.4	1.7
Medication for cholesterol, blood pressure or diabetes	1.8	3.0	5.3	-1.6	-1.6	-1.9	-1.6	-1.6	-1.9	-1.5	-1.9	-2.0	-1.8	-1.5	-2.0	-1.8	-0.7	-2.3	-1.5	-1.9	-1.7
Ulcerative Colitis (UC)	1.7	3.2	5.7	-1.3	-1.4	-1.3	-2.3	-2.1	-1.9	-1.7	-1.7	-1.4	-1.9	-2.4	-1.7	-1.2	-1.8	-1.5	-2.0	-1.7	-2.4
Stomach or abdominal pain in last month	1.7	2.1	4.3	-1.3	-1.5	-2.1	-1.1	-1.1	-2.0	-0.4	-1.7	-1.9	-1.4	-1.3	-1.5	-1.9	0.3	-1.6	-1.3	-1.2	-1.1
Financial difficulties in last 2 years	1.7	2.3	5.3	2.1	2.3	1.2	1.6	1.4	1.3	2.3	1.0	1.7	1.9	1.5	1.2	0.6	0.2	1.6	1.0	1.1	1.6
Diabetes (self-reported)	1.7	2.6	6.3	2.5	2.5	1.3	1.4	1.4	1.6	2.2	0.9	2.2	2.0	1.4	1.2	0.5	-0.3	2.0	1.1	0.9	1.4
Medication: Bendroflumethiazide	1.7	2.6	9.5	0.7	0.6	-0.7	-2.1	-2.1	-1.3	-0.2	-1.7	0.2	-0.8	-2.1	-1.7	-1.1	-3.1	-0.3	-2.3	-1.8	-2.1
Mouth/teeth dental problems: Dentures	1.6	2.7	4.4	1.5	1.3	1.4	1.9	2.0	1.9	1.7	1.5	1.8	2.1	1.8	1.8	0.9	0.9	1.6	1.9	1.4	1.8
Medication: Allopurinol	1.6	2.2	4.2	1.9	2.1	1.7	1.5	1.3	1.6	1.6	1.2	1.8	1.8	1.7	1.2	1.3	-0.1	1.4	1.1	1.1	1.4
Back pain experienced in last month	1.6	2.3	4.2	-0.8	-0.7	-1.9	-1.4	-1.4	-1.8	-0.5	-1.9	-1.4	-1.2	-1.4	-1.7	-2.1	-1.4	-1.8	-1.5	-1.9	-1.4
Pack years of smoking	1.6	2.3	3.3	1.4	1.2	1.5	1.7	1.7	1.8	1.3	1.5	1.8	1.8	1.6	1.7	1.1	0.7	1.7	1.6	1.4	1.7
Arm fat percentage (right)	1.5	6.0	9.3	1.8	1.8	2.0	3.0	2.9	2.6	2.3	2.4	2.1	2.7	2.9	2.6	1.7	1.9	2.3	2.7	2.5	3.0
Illnesses of mother	1.5	1.9	4.2	0.4	0.5	-1.7	-1.0	-1.3	-1.6	0.5	-1.8	-1.3	-0.9	-1.0	-1.8	-2.1	-1.5	-1.5	-1.6	-1.7	-1.1
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	7.0	-2.6	-2.6	-1.2	-0.9	-0.7	-0.9	-2.2	-0.4	-1.6	-1.6	-1.0	-0.5	-0.4	0.7	-1.4	-0.3	-0.6	-0.9
Medication: Gliclazide	1.5	1.7	3.8	1.9	1.9	1.1	1.4	1.2	1.1	1.8	0.9	1.3	1.5	1.3	1.0	0.6	0.1	1.4	0.9	1.0	1.3
Leg fat mass (left)	1.5	5.7	9.3	1.8	1.9	1.8	3.0	2.9	2.5	2.5	2.3	1.9	2.7	2.9	2.5	1.5	1.7	2.1	2.6	2.4	3.0
Had other major operations	1.4	1.7	4.4	-0.2	0.1	1.0	1.5	1.6	1.3	0.4	1.5	0.5	1.0	1.5	1.5	1.2	2.1	0.7	1.8	1.6	1.5
Leg fat percentage (right)	1.4	5.0	9.2	0.9	0.8	1.4	3.0	2.9	2.1	1.9	2.3	1.1	2.1	2.7	2.5	1.5	2.7	1.8	2.7	2.6	3.0
Leg fat mass (right)	1.4	5.5	9.2	1.6	1.6	1.8	3.0	2.9	2.4	2.2	2.3	1.8	2.5	2.9	2.5	1.6	2.0	2.1	2.7	2.4	3.0
Breast cancer (self-reported)	1.4	1.7	3.9	-1.8	-1.8	-1.1	-1.4	-1.2	-1.1	-2.0	-1.0	-1.2	-1.5	-1.4	-1.1	-0.8	-0.4	-1.3	-0.9	-1.1	-1.4
Heart disease (siblings)	1.4	1.7	3.7	-0.2	0.0	1.2	1.4	1.4	1.3	0.1	1.7	0.4	0.8	1.4	1.6	1.6	1.9	0.9	1.6	1.7	1.4
Number of treatments/medications taken	1.3	2.4	4.0	1.4	1.4	1.1	1.8	1.9	1.4	2.0	1.3	1.3	1.8	1.7	1.6	0.8	1.2	1.5	1.7	1.5	1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	2.4	1.3	1.3	1.0	1.5	1.5	1.3	1.6	1.1	1.2	1.5	1.4	1.3	0.7	0.8	1.5	1.3	1.3	1.5
Leg pain on walking	1.3	1.6	3.1	-1.7	-1.8	-1.7	-1.0	-1.0	-1.3	-1.4	-1.2	-1.4	-1.5	-1.3	-1.0	-1.3	-0.2	-1.0	-1.1	-1.1	-1.0
Qualifications: nursing, teaching	1.3	2.0	2.9	0.7	0.5	1.5	1.4	1.4	1.6	0.7	1.6	1.4	1.4	1.3	1.7	1.6	1.4	1.6	1.5	1.7	1.5
Number of self-reported non-cancer illnesses	1.3	2.2	4.2	1.5	1.4	0.9	1.7	1.8	1.5	2.0	1.1	1.6	1.9	1.6	1.6	0.4	0.8	1.4	1.6	1.1	1.7
Leg fat percentage (left)	1.3	4.7	8.8	1.2	1.1	1.4	3.0	2.8	2.0	2.2	2.1	1.2	2.2	2.6	2.4	1.3	2.3	1.8	2.5	2.4	2.9
Myopia	1.3	1.9	4.1	1.5	1.4	1.8	1.1	0.9	1.5	1.0	1.3	2.0	1.5	1.0	1.4	1.6	-0.2	2.0	0.8	1.3	1.0
Townsend deprivation index at recruitment	1.2	1.6	4.9	2.1	2.2	0.9	1.2	1.2	1.0	2.2	0.5	1.3	1.6	1.3	0.6	-0.0	-0.3	1.0	0.9	0.5	1.2
Asthma	1.2	2.3	4.1	-0.4	-0.5	-1.6	-1.6	-1.5	-1.7	-0.4	-2.0	-1.2	-1.3	-1.6	-1.8	-2.0	-1.4	-1.6	-1.6	-1.9	-1.6
Birth weight	1.2	2.6	8.0	-0.6	-0.5	2.0	1.1	1.2	2.0	-1.1	2.3	1.3	0.8	1.3	2.0	2.8	1.6	1.5	1.7	1.9	1.1
Health satisfaction	1.2	1.6	4.5	-1.6	-1.5	-0.7	-1.6	-1.5	-1.0	-2.1	-0.8	-1.0	-1.5	-1.4	-1.1	-0.2	-0.8	-1.1	-1.1	-1.1	-1.5
Arm fat percentage (left)	1.2	4.7	7.3	1.7	1.6	1.8	2.7	2.6	2.3	2.2	2.1	1.9	2.5	2.6	2.3	1.5	1.7	2.1	2.4	2.2	2.7
Ever depressed for a whole week	1.2	1.4	2.1	-0.9	-1.2	-1.1	-1.3	-1.3	-1.1	-1.5	-1.2	-0.8	-1.4	-1.5	-1.3	-1.0	-1.1	-0.8	-1.3	-1.3	-1.3
Qualifications: A levels/AS levels or equivalent	1.1	2.4	4.2	-1.6	-1.6	-2.0	-1.4	-1.2	-1.6	-1.2	-1.6	-1.8	-1.6	-1.3	-1.6	-1.9	-0.3	-2.0	-1.1	-1.7	-1.3
Exposure to tobacco smoke at home	1.1	1.2	2.1	0.7	0.7	1.3	1.2	1.2	1.0	0.9	1.3	0.6	1.0	1.3	1.2	1.4	1.0	0.9	1.2	1.4	1.2
Body fat percentage	1.1	4.3	7.0	1.7	1.5	1.5	2.7	2.5	2.0	2.4	1.9	1.7	2.3	2.4	2.2	1.1	1.6	2.0	2.2	2.1	2.6
Supplements: Calcium	1.1	1.3	2.8	0.4	0.1	-1.2	-1.2	-1.1	-1.2	0.5	-1.5	-0.5	-0.6	-1.2	-1.1	-1.6	-1.7	-0.8	-1.3	-1.4	-1.1
Irritable Bowel Disease (IBD)	1.0	2.4	4.6	-1.2	-1.2	-0.8	-2.1	-2.0	-1.6	-1.7	-1.2	-1.2	-1.7	-2.1	-1.4	-0.5	-1.5	-1.1	-1.8	-1.3	-2.1
Major Depression (MDD)	1.0	1.2	2.1	-1.2	-1.1	-1.1	-1.1	-1.2	-1.1	-1.4	-0.9	-1.2	-1.4	-1.0	-1.1	-0.6	-0.2	-1.3	-1.0	-1.0	-1.0
Fasting Glucose	1.0	1.2	1.9	-1.4	-1.2	-0.9	-1.1	-1.3	-1.2	-1.4	-0.8	-1.2	-1.4	-1.2	-1.0	-0.4	-0.6	-1.0	-1.2	-0.8	-1.2
Blood Red Count	1.0	9.6	41.7	-6.5	-6.3	-1.5	-0.1	0.0	-0.7	-4.9	1.1	-4.0	-2.8	0.1	0.5	1.3	5.2	-2.9	1.3	1.1	0.1
Medication: Metformin	1.0	1.5	4.2	2.1	1.9	0.8	1.1	1.1	1.1	1.9	0.4	1.7	1.5	0.9	0.7	-0.1	-0.5	1.5	0.7	0.4	1.0
Waist circumference	1.0	3.8	7.0	0.9	0.9	1.1	2.6	2.6	1.9	2.0	1.8	1.1	2.0	2.4	2.2	0.9	2.2	1.5	2.5	2.0	2.6
Medication: Ramipril	1.0	1.2	2.7	1.5	1.4	1.2	0.7	0.7	1.2	1.3	1.0	1.6	1.4	0.6	1.2	0.8	-0.4	1.6	0.6	0.8	0.7
Falls in the last year	1.0	1.3	5.6	-0.8	-0.6	0.3	1.4	1.4	1.1	-0.3	1.2	-0.0	0.6	1.5	1.0	0.8	2.4	0.1	1.7	1.1	1.4
Arm fat mass (right)	1.0	4.1	6.6	1.7	1.8	1.4	2.6	2.5	2.1	2.3	1.8	1.7	2.4	2.5	2.1	1.1	1.4	1.8	2.2	1.8	2.5
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.1	2.8	-1.2	-1.3	-0.8	-1.3	-1.4	-0.8	-1.7	-0.7	-0.6	-1.2	-1.2	-0.9	-0.2	-1.0	-0.8	-1.2	-1.0	-1.3
Trunk fat percentage	0.9	3.4	5.4	1.8	1.6	1.3	2.3	2.2	1.9	2.3	1.5	1.8	2.2	2.1	1.9	0.8	1.0	1.9	1.9	1.6	2.2
Multivitamins +/- minerals	0.9	1.1	3.3	1.0	0.7	-1.2	-0.6	-0.8	-1.1	1.1	-1.5	-0.5	-0.3	-0.8	-1.2	-1.8	-1.5	-0.6	-1.2	-1.3	-0.6
Loud music exposure frequency	0.9	1.0	3.3	-1.8	-1.4	0.7	0.2	0.5	0.5	-1.7	1.0	-0.5	-0.4	0.6	0.7	1.4	1.6	-0.5	1.1	0.8	0.2
Medication: Seretide 50 evohaler	0.9	1.0	4.2	1.8	1.7	0.6	0.9	0.8	0.6	2.0	0.3	0.9	1.1	0.7	0.5	-0.1	-0.0	1.1	0.5	0.6	0.9
Whole body fat mass	0.9	3.8	6.3	1.9	1.8	1.3	2.5	2.4	1.9	2.5	1.6	1.7	2.3	2.3	2.0	0.8	1.1	1.9	2.0	1.8	2.4
Eye problems/disorders: Cataract	0.9	1.0	2.7	1.5	1.2	0.5	0.9	1.2	1.0	1.7	0.5	1.2	1.3	0.9	0.9	-0.1	-0.0	1.1	1.0	0.5	1.0
Asthma (self-reported)	0.9	1.8	3.9	-0.2	-0.3	-1.5	-1.4	-1.2	-1.5	-0.1	-1.9	-1.0	-1.0	-1.4	-1.6	-2.0	-1.3	-1.4	-1.4	-1.8	-1.4
Guilty feelings	0.9	1.4	4.2	0.7	0.5	-1.5	-0.7	-1.0	-1.2	0.6	-1.7	-0.3	-0.4	-1.0	-1.5	-2.0	-1.6	-0.5	-1.6	-1.6	-0.8
Hearing aid user	0.9	1.1	2.1	-1.1	-1.3	-1.0	-1.2	-1.2	-1.0	-1.5	-0.9	-0.8	-1.2	-1.2	-1.0	-0.5	-0.2	-0.7	-1.1	-0.8	-1.2
Schizophrenia vs Biploar Disorder	0.8	1.1	3.0	1.6	1.4	1.0	0.9	0.8	0.7	1.7	0.7	1.1	1.2	0.7	0.9	0.7	-0.4	1.3	0.5	0.9	0.8
Age at First Birth	0.8	1.2	3.1	-1.3	-1.0	-0.9	-1.0	-1.2	-1.0	-1.8	-0.8	-1.2	-1.3	-0.9	-1.2	-0.3	-0.4	-1.5	-1.0	-1.1	-1.3
Body Mass Index (BMI) (2010)	0.8	1.0	1.9	1.2	1.4	1.1	1.0	1.0	1.0	1.2	0.9	1.0	1.1	1.0	0.9	0.8	0.4	1.1	0.9	0.9	1.1
Primary Biliary Cirrhosis	0.8	1.1	2.0	0.3	0.5	-1.0	-1.0	-1.0	-1.2	0.2	-1.4	-0.7	-0.7	-1.0	-1.4	-1.4	-1.4	-0.9	-1.2	-1.3	-1.0
Body mass index (BMI)	0.8	3.5	6.3	1.1	1.2	1.3	2.5	2.4	1.9	1.7	1.8	1.3	2.0	2.4	2.0	1.1	1.8	1.5	2.3	1.9	2.4
Trunk fat mass	0.8	3.3	5.9	1.9	1.8	1.2	2.3	2.2	1.8	2.4	1.4	1.7	2.2	2.1	1.8	0.7	0.9	1.7	1.8	1.5	2.2
Happiness	0.8	1.0	2.0	-0.7	-0.8	-0.8	-1.2	-1.1	-0.6	-1.4	-0.9	-0.3	-0.9	-1.0	-1.0	-0.7	-1.4	-0.9	-1.0	-1.4	-1.2
Breastfed as a baby	0.8	0.9	3.1	-1.6	-1.4	-0.4	-0.9	-0.9	-0.7	-1.8	-0.2	-1.3	-1.3	-0.7	-0.6	0.2	0.3	-1.1	-0.6	-0.3	-0.9
Neck or shoulder pain in last month	0.8	1.1	3.3	-1.4	-1.8	-1.3	-1.0	-0.9	-1.0	-1.3	-0.8	-1.1	-1.3	-1.1	-0.8	-0.7	0.3	-0.9	-0.8	-0.7	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	2.5	1.3	1.2	0.9	0.8	0.5	0.9	0.9	0.7	1.4	1.0	0.6	0.7	0.7	-0.4	1.6	0.2	0.7	0.7
Commuting to job workplace: Walk	0.8	0.8	1.2	0.9	0.7	0.8	1.0	1.0	1.0	1.0	0.9	1.0	1.1	1.1	1.0	0.7	0.4	0.9	0.9	0.8	1.0
Osteoarthritis (self-reported)	0.8	1.0	2.2	1.3	1.1	0.9	0.9	0.7	1.1	1.1	0.8	1.5	1.2	0.8	1.1	0.8	-0.5	1.4	0.5	0.7	0.9
Arm fat mass (left)	0.8	3.4	5.5	1.6	1.6	1.3	2.3	2.3	1.8	2.2	1.6	1.5	2.2	2.3	1.8	0.9	1.3	1.6	2.0	1.7	2.3
Average weekly beer plus cider intake	0.8	1.1	2.4	-0.3	-0.4	-0.6	-1.4	-1.5	-0.8	-1.2	-1.0	-0.2	-1.0	-1.3	-1.1	-0.5	-1.6	-0.4	-1.5	-1.1	-1.4
Unable to work because of sickness or disability	0.8	1.1	5.3	-1.3	-1.3	-0.3	1.1	1.2	0.5	-0.2	0.8	-0.7	0.1	1.2	0.8	0.3	2.3	-0.6	1.4	0.9	1.2
Pain experienced in last month	0.8	1.3	2.7	1.5	1.6	1.2	1.0	0.9	1.2	1.2	0.9	1.5	1.3	0.9	1.0	0.8	-0.2	1.5	0.8	0.9	1.0
Bipolar Disorder or Schizophrenia	0.7	1.8	3.1	-0.8	-1.0	-1.5	-1.5	-1.3	-1.4	-0.7	-1.6	-1.0	-1.3	-1.6	-1.4	-1.8	-1.1	-1.1	-1.4	-1.6	-1.5
Blood Platelet Count	0.7	8.0	33.8	5.8	5.7	1.9	0.4	0.6	1.3	4.7	-0.2	3.7	3.0	0.5	0.3	-0.6	-4.4	2.7	-0.3	-0.4	0.4
Medication: Lansoprazole	0.7	0.8	1.6	-0.6	-0.7	-0.5	-1.2	-1.1	-0.8	-1.0	-0.8	-0.5	-1.0	-1.1	-0.8	-0.4	-1.0	-0.7	-1.0	-0.9	-1.2
Prospective memory result	0.7	0.9	3.2	-1.8	-1.6	-0.9	-0.4	-0.4	-0.6	-1.3	-0.2	-1.4	-1.0	-0.2	-0.3	-0.1	1.1	-1.4	-0.1	-0.2	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	4.2	2.1	1.8	0.4	0.7	0.5	0.6	1.6	-0.0	1.4	1.2	0.5	0.2	-0.3	-0.9	1.3	-0.0	0.0	0.6
Ever highly irritable/argumentative for 2 days	0.7	0.8	1.5	-0.4	-0.4	-0.7	-1.1	-1.2	-0.9	-0.9	-0.9	-0.5	-0.9	-1.2	-1.0	-0.6	-1.0	-0.5	-1.2	-0.9	-1.2
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	1.5	0.6	0.5	0.6	1.1	1.0	1.1	0.7	1.0	0.9	1.1	1.2	1.0	0.8	0.9	0.9	0.9	1.0	1.2
Number of full brothers	0.7	0.9	1.8	-0.4	-0.4	-1.1	-1.0	-1.0	-1.3	-0.4	-1.1	-1.2	-1.1	-1.1	-1.2	-1.1	-0.3	-0.7	-1.2	-0.8	-0.9
Overall health rating	0.7	1.5	4.5	2.0	1.8	0.8	1.1	1.4	1.0	2.1	0.5	1.4	1.6	1.1	0.7	-0.2	0.1	1.3	1.0	0.6	1.2
Age at last live birth	0.7	1.0	1.7	-1.1	-1.1	-0.9	-1.1	-1.1	-0.9	-1.3	-0.8	-0.7	-1.1	-1.1	-0.9	-0.5	-0.3	-0.8	-1.0	-0.9	-1.1
Knee pain experienced in last month	0.7	1.1	1.8	-1.3	-1.3	-1.1	-1.0	-1.0	-1.1	-1.2	-0.9	-1.3	-1.3	-0.9	-1.0	-0.6	-0.2	-1.3	-0.9	-0.9	-0.9
Ever had bowel cancer screening	0.7	0.9	1.7	0.7	0.6	1.3	0.8	0.8	0.9	0.8	1.0	1.1	1.0	0.6	1.1	1.1	0.5	1.3	0.8	1.2	0.8
Medication: Atorvastatin	0.7	0.9	2.7	1.5	1.6	0.3	1.0	0.9	0.7	1.6	0.3	0.9	1.2	0.9	0.5	-0.2	0.0	0.9	0.6	0.3	0.9
Bipolar Disorder (2018)	0.6	1.0	2.7	-1.6	-1.7	-1.0	-0.9	-0.6	-0.7	-1.4	-0.8	-1.1	-1.1	-0.7	-0.8	-0.8	0.5	-1.2	-0.4	-0.8	-0.8
Schizophrenia (2018)	0.6	1.3	3.2	0.3	0.0	-1.0	-1.2	-1.2	-1.3	0.2	-1.5	-0.4	-0.7	-1.5	-1.2	-1.6	-1.8	-0.4	-1.5	-1.4	-1.2
Bipolar Disorder (2011)	0.6	0.5	2.3	-1.3	-1.0	-0.2	0.5	0.6	0.4	-0.7	0.6	-0.5	-0.1	0.6	0.6	0.4	1.5	-0.4	0.9	0.5	0.6
Cardiovascular Disease	0.6	1.9	3.9	1.6	1.5	0.9	1.4	1.5	1.4	2.0	1.1	1.6	1.8	1.4	1.4	0.5	0.4	1.5	1.3	1.0	1.5
Hearing difficulty/problems: Yes	0.6	0.9	5.5	-0.8	-0.7	-0.1	1.2	1.0	0.6	-0.2	0.9	-0.5	0.2	1.2	0.7	0.6	2.3	-0.1	1.2	1.0	1.1
Angina	0.6	0.7	2.0	-0.1	0.0	0.9	0.7	0.7	1.1	-0.4	1.2	0.6	0.6	1.0	0.9	1.4	1.1	0.4	1.1	0.9	0.6
Vitamin and mineral supplements	0.6	0.8	1.6	-0.0	0.1	1.1	0.7	0.9	1.2	-0.3	1.2	1.0	0.8	0.9	1.1	1.2	0.8	0.8	1.2	0.9	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	2.7	-0.8	-0.6	-0.9	-1.2	-1.4	-0.9	-1.6	-1.0	-0.7	-1.2	-1.2	-1.3	-0.6	-1.1	-1.0	-1.3	-1.3	-1.4
Medication: Levothyroxine sodium	0.6	1.0	2.1	-1.5	-1.3	-1.1	-0.9	-0.8	-1.1	-1.2	-0.8	-1.4	-1.2	-0.8	-0.9	-0.7	0.2	-1.4	-0.6	-0.8	-0.8
Chronic bronchitis/emphysema (father)	0.6	0.7	2.0	1.0	0.9	1.1	0.6	0.6	1.1	0.3	0.7	1.4	1.0	0.7	0.7	0.8	-0.2	1.0	0.5	0.5	0.6
Hair/balding pattern: Pattern 2	0.6	0.8	2.0	1.3	1.4	0.9	0.9	0.8	0.8	1.2	0.6	0.8	1.0	1.0	0.6	0.6	-0.0	0.7	0.7	0.7	0.8
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.3	-0.8	-0.8	-1.1	-0.6	-0.7	-0.9	-0.8	-0.8	-1.0	-0.9	-0.7	-1.0	-0.9	-0.1	-0.9	-0.8	-0.8	-0.6
Qualifications: None of the above	0.6	1.3	2.4	0.5	0.6	1.0	1.3	1.5	1.2	0.8	1.2	0.7	1.0	1.4	1.2	0.9	1.3	0.8	1.6	1.2	1.4
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.0	-0.0	-0.3	-0.4	-1.3	-1.1	-0.9	-0.5	-1.1	-0.2	-0.8	-1.4	-0.9	-0.7	-1.1	-0.3	-1.2	-0.9	-1.3
Number of children fathered	0.6	0.6	4.3	-1.0	-1.1	-0.2	0.7	0.6	0.2	-0.2	0.7	-0.6	-0.1	0.4	0.8	0.5	2.1	0.3	0.7	1.1	0.8
Financial situation satisfaction	0.6	0.7	4.0	1.1	0.8	-0.2	-0.6	-0.8	-0.3	0.3	-0.8	0.7	0.0	-0.8	-0.7	-0.7	-2.0	0.4	-1.1	-0.9	-0.7
Number of operations (self-reported)	0.6	0.9	1.9	-0.0	0.1	0.3	1.3	1.2	0.8	0.6	1.0	0.4	0.8	1.1	1.2	0.6	1.4	0.8	1.1	1.2	1.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.2	1.0	0.9	0.7	0.8	1.0	0.9	1.1	0.6	1.0	1.0	0.7	0.8	0.3	0.2	0.9	0.9	0.6	0.8
Depressed Affect (Nagel 2018)	0.5	1.1	5.9	2.1	1.9	-0.2	0.5	0.5	-0.1	2.4	-0.7	0.6	1.1	0.3	-0.2	-1.4	-0.8	0.5	-0.1	-0.4	0.5
Alzheimer’s Disease (including proxy)	0.5	0.8	2.8	-1.7	-1.6	0.1	0.2	0.3	0.1	-1.3	0.7	-0.9	-0.5	0.4	0.5	0.8	1.6	-0.7	0.7	0.6	0.4
BMI	0.5	2.7	4.6	1.7	1.9	1.1	2.1	2.0	1.5	2.1	1.3	1.4	1.9	1.9	1.5	0.6	1.0	1.5	1.6	1.4	2.1
Supplements: Zinc	0.5	0.6	2.1	1.4	1.1	-0.5	-0.1	-0.2	-0.2	1.3	-0.7	0.7	0.4	-0.3	-0.3	-0.9	-1.4	0.5	-0.7	-0.6	-0.1
Sitting height	0.5	3.5	7.6	-0.1	-0.4	-1.6	-2.2	-2.2	-1.7	-0.9	-2.2	-0.7	-1.4	-2.1	-2.2	-1.9	-2.8	-1.4	-2.3	-2.5	-2.2
Father’s age at death	0.5	0.7	1.1	0.4	0.5	0.8	0.9	0.8	1.0	0.3	1.0	0.8	0.8	0.8	1.1	1.0	0.7	0.9	0.9	1.0	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	2.8	-0.2	-0.3	-1.4	-0.6	-0.7	-1.0	0.0	-1.3	-0.7	-0.5	-0.7	-1.1	-1.7	-0.8	-1.1	-0.9	-1.3	-0.6
Pulse rate	0.5	0.8	3.0	-0.7	-0.9	0.7	0.7	0.9	0.6	-0.1	1.0	-0.2	0.2	0.7	1.0	1.1	1.7	0.2	1.1	1.2	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.6	-1.2	-1.1	-1.2	-0.2	-0.3	-0.8	-0.9	-0.6	-1.2	-0.9	-0.3	-0.7	-0.8	0.6	-0.9	-0.3	-0.5	-0.2
Lung cancer (father)	0.5	0.5	2.6	-0.4	-0.7	-0.3	1.0	1.0	0.3	0.4	0.5	-0.3	0.3	0.7	0.7	-0.1	1.6	0.2	1.0	0.7	1.0
Pulse wave peak to peak time	0.5	0.6	1.7	1.0	0.9	-0.1	1.0	0.8	0.6	1.3	0.1	0.9	1.1	0.7	0.5	-0.5	0.1	0.8	0.5	0.1	0.9
Angina (self-reported)	0.5	0.6	1.9	-0.1	0.1	0.9	0.6	0.6	1.2	-0.4	1.2	0.7	0.6	1.0	0.9	1.4	0.8	0.4	1.0	0.8	0.6
Mean time to correctly identify matches	0.5	1.0	2.2	1.1	1.0	0.9	1.1	1.3	0.7	1.5	0.8	0.5	0.9	0.9	0.9	0.5	1.0	1.2	1.0	1.2	1.2
Pulse rate, automated reading	0.5	1.7	3.6	-0.1	-0.3	1.2	1.4	1.7	1.2	0.7	1.5	0.5	1.0	1.2	1.7	1.2	1.9	1.0	1.8	1.7	1.4
Medication: Aspirin	0.5	0.6	1.2	0.6	0.6	0.4	1.0	0.9	0.7	0.9	0.7	0.5	0.7	0.9	0.8	0.5	0.9	0.9	0.8	0.9	1.1
Supplements: Vitamin C	0.5	0.6	1.9	-0.7	-0.8	-1.0	-0.5	-0.8	-1.3	-0.3	-0.7	-1.4	-1.1	-0.8	-0.8	-0.5	0.3	-0.6	-1.0	-0.2	-0.5
Illnesses of father: Heart disease	0.5	0.8	4.9	1.1	1.1	-0.3	-0.7	-0.6	-0.3	0.6	-0.8	0.4	0.1	-0.5	-0.7	-0.9	-2.2	-0.3	-0.8	-1.1	-0.7
Wears glasses or contact lenses	0.5	0.6	1.2	0.2	0.0	0.8	0.7	0.8	0.7	0.5	0.9	0.3	0.5	0.7	1.0	0.9	0.9	0.7	0.9	1.1	0.8
Risk taking	0.5	0.7	1.4	0.4	0.6	0.6	1.1	0.9	0.8	0.5	0.9	0.5	0.9	1.2	0.9	0.8	0.7	0.5	0.9	0.8	1.0
Alcohol drinker status: Previous	0.5	0.5	1.5	1.1	0.9	0.8	0.4	0.7	0.9	0.9	0.5	1.2	1.0	0.5	0.6	0.2	-0.4	0.9	0.7	0.2	0.4
HbA1C	0.4	0.5	2.3	1.1	1.5	-0.4	0.9	0.3	0.5	0.9	0.2	0.6	0.7	0.9	0.3	-0.1	0.2	0.4	0.1	0.2	0.9
LDL Cholesterol	0.4	0.6	1.7	-0.2	-0.2	-1.1	-0.5	-0.5	-0.7	-0.1	-1.0	-0.7	-0.5	-0.5	-1.0	-1.3	-0.7	-1.0	-0.6	-1.1	-0.5
Neuroticism (2016)	0.4	0.5	2.3	1.3	1.2	0.1	0.9	0.8	0.3	1.5	-0.1	0.6	0.8	0.4	0.2	-0.5	-0.4	0.5	0.4	0.1	0.8
Blood Eosinophil Count	0.4	3.1	10.4	1.8	1.4	-1.4	-1.5	-1.4	-1.5	1.4	-2.3	0.1	-0.4	-1.8	-1.8	-2.6	-3.2	-0.5	-2.1	-2.2	-1.6
Lung FEV1/FVC ratio	0.4	2.1	3.4	1.0	1.1	1.4	1.6	1.5	1.7	0.8	1.7	1.3	1.5	1.9	1.5	1.5	0.8	1.2	1.6	1.4	1.6
Ever had hysterectomy (womb removed)	0.4	0.4	2.5	1.0	0.7	-0.1	0.7	0.7	0.1	1.6	-0.0	0.3	0.7	0.5	0.3	-0.5	0.5	0.6	0.3	0.4	0.8
Qualifications: CSEs or equivalent	0.4	0.5	1.0	0.3	0.4	-0.6	-0.5	-0.7	-0.8	0.2	-1.0	-0.3	-0.4	-0.7	-1.0	-0.9	-1.0	-0.4	-0.9	-0.9	-0.6
Hayfever, allergic rhinitis or eczema	0.4	0.8	2.9	0.0	-0.1	-0.6	-0.9	-1.2	-0.5	-1.0	-0.8	0.1	-0.6	-0.7	-1.0	-0.3	-1.7	-0.4	-1.3	-1.2	-1.0
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.6	0.9	1.0	1.0	0.1	-0.1	0.7	0.3	0.7	1.3	0.7	0.2	0.6	1.1	-0.6	1.1	0.0	0.5	0.0
Medication: Atenolol	0.4	0.5	1.4	1.1	1.1	0.6	0.5	0.6	0.5	1.2	0.3	0.9	0.8	0.3	0.5	0.1	-0.1	1.0	0.4	0.4	0.5
Number of incorrect matches in round	0.4	0.6	2.3	-0.7	-0.5	0.6	0.8	0.7	0.7	-0.5	0.9	-0.0	0.2	0.9	0.8	1.2	1.5	0.1	1.0	1.0	0.8
Alcohol usually taken with meals	0.4	0.6	2.5	-1.1	-1.1	-1.1	-0.1	-0.2	-0.8	-0.2	-0.4	-1.6	-0.8	-0.2	-0.4	-0.7	0.8	-1.2	-0.2	-0.2	-0.1
Hearing difficulty/problems with background noise	0.4	0.7	3.9	-0.3	-0.6	-0.1	1.1	1.1	0.5	0.5	0.7	0.0	0.5	0.6	1.0	0.1	2.0	0.9	0.9	1.1	1.1
Hip circumference	0.4	1.8	3.2	0.8	0.9	0.9	1.8	1.8	1.4	1.4	1.3	1.0	1.5	1.7	1.5	0.7	1.2	1.0	1.7	1.3	1.8
Hair/balding pattern: Pattern 3	0.4	0.7	2.4	1.5	1.6	-0.3	-0.1	-0.2	-0.3	1.4	-0.7	0.5	0.5	-0.2	-0.5	-1.0	-1.3	0.3	-0.6	-0.6	-0.1
Pulse wave Arterial Stiffness index	0.4	0.5	1.7	-1.0	-0.9	0.3	-0.8	-0.7	-0.5	-1.3	0.1	-0.7	-1.0	-0.6	-0.3	0.8	0.0	-0.5	-0.4	0.1	-0.8
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.8	-1.4	-1.1	-1.0	-0.4	-0.4	-0.6	-1.0	-0.5	-1.1	-0.8	-0.3	-0.7	-0.6	0.6	-1.2	-0.2	-0.6	-0.4
Hypothyroidism/myxoedema (self-reported)	0.4	0.9	2.8	-1.7	-1.5	-0.9	-0.4	-0.1	-0.7	-0.9	-0.4	-1.6	-0.9	-0.3	-0.4	-0.6	1.1	-1.5	0.2	-0.3	-0.3
Forced vital capacity (FVC), Best measure	0.4	1.4	2.8	-0.3	-0.4	-1.1	-1.4	-1.3	-1.0	-0.9	-1.4	-0.5	-0.9	-1.1	-1.5	-1.2	-1.5	-1.2	-1.3	-1.7	-1.4
Comparative body size at age 10	0.4	1.1	4.2	2.0	2.0	0.7	0.2	-0.1	0.7	0.8	-0.2	1.8	1.1	0.3	-0.1	0.1	-2.0	0.9	-0.4	-0.6	-0.0
Wheeze or whistling in the chest in last year	0.4	0.7	2.8	-0.4	-0.5	-1.3	-0.4	-0.3	-0.9	0.0	-1.1	-0.9	-0.5	-0.5	-0.9	-1.7	-0.1	-1.1	-0.5	-1.1	-0.4
Medication: Omeprazole	0.4	0.5	1.0	0.5	0.4	0.8	0.7	0.8	1.0	0.4	0.9	0.8	0.7	0.7	0.9	0.7	0.5	0.7	0.9	0.7	0.7
Heart disease (mother)	0.4	0.4	0.9	0.2	0.0	0.6	0.7	0.9	0.8	0.3	0.6	0.8	0.6	0.6	0.8	0.4	0.4	0.9	0.9	0.6	0.8
Handedness (chirality/laterality): Left-handed	0.4	0.4	0.8	0.6	0.8	0.9	0.7	0.6	0.5	0.6	0.7	0.5	0.6	0.6	0.6	0.8	0.4	0.7	0.5	0.8	0.7
Loneliness, isolation	0.4	0.5	2.4	0.5	0.5	-1.0	-0.2	-0.3	-0.8	0.7	-1.1	-0.4	-0.2	-0.4	-0.9	-1.5	-0.6	-0.4	-0.7	-0.9	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.4	1.2	1.0	0.5	0.8	0.9	0.8	1.1	0.4	1.0	1.1	0.8	0.6	0.1	-0.0	0.9	0.7	0.4	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.0	-0.9	-0.9	-0.7	-0.7	-0.6	-0.5	-0.9	-0.5	-0.5	-0.6	-0.5	-0.5	-0.4	-0.4	-1.0	-0.4	-0.8	-0.7
Average weekly champagne plus white wine intake	0.4	0.5	1.6	-0.2	-0.3	-1.0	-0.5	-0.4	-1.0	0.4	-0.9	-0.9	-0.6	-0.8	-0.8	-1.2	-0.1	-0.5	-0.7	-0.6	-0.5
Cholesterol lowering medication	0.4	0.6	2.3	-0.8	-0.6	-1.4	0.1	-0.1	-0.8	-0.1	-0.6	-1.5	-0.7	0.1	-0.7	-1.0	1.0	-1.3	-0.1	-0.4	0.1
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.4	0.6	0.7	1.1	0.4	0.2	0.8	-0.1	0.7	1.1	0.6	0.4	0.6	1.2	-0.1	1.2	0.1	0.7	0.4
Coronary Artery Disease (CAD)	0.3	0.4	0.8	-0.3	-0.2	0.7	0.8	0.6	0.9	-0.6	0.8	0.4	0.4	0.6	0.7	0.9	0.7	0.2	0.8	0.5	0.4
Mean Putamen Volume	0.3	0.4	0.8	-0.0	0.2	0.3	0.9	0.8	0.6	0.1	0.7	0.2	0.5	0.9	0.6	0.4	0.8	0.3	0.8	0.6	0.8
Schizophrenia (2014)	0.3	0.7	1.5	-0.3	-0.4	-0.8	-0.9	-0.8	-1.1	-0.2	-1.0	-0.8	-0.9	-1.2	-0.8	-1.1	-0.9	-0.6	-1.0	-0.8	-0.9
Respiratory disease	0.3	0.6	1.8	1.3	1.2	-0.3	-0.3	-0.1	-0.4	1.3	-0.9	0.2	0.3	-0.2	-0.7	-1.2	-1.1	-0.2	-0.5	-0.8	-0.3
Chronotype (morning person)	0.3	0.7	1.6	0.9	0.8	1.0	0.6	0.5	1.0	0.7	0.9	1.3	1.0	0.6	1.0	1.0	0.1	1.2	0.5	0.8	0.5
Sensitivity / hurt feelings	0.3	0.6	1.9	0.7	0.9	-0.2	1.2	1.0	0.4	1.4	0.3	0.2	0.9	1.0	0.5	-0.3	0.6	0.4	0.7	0.5	1.2
Current tobacco smoking	0.3	0.5	1.7	1.3	1.2	0.8	0.1	0.2	0.6	0.8	0.4	1.1	0.8	0.3	0.3	0.5	-0.6	0.9	0.2	0.2	0.1
Fed-up feelings	0.3	0.5	2.7	1.2	1.0	-0.6	0.5	0.3	-0.4	1.7	-0.7	-0.0	0.5	0.2	-0.4	-1.3	-0.3	0.1	-0.2	-0.3	0.5
Nervous feelings	0.3	0.5	1.3	-0.7	-0.7	-1.0	-0.6	-0.2	-0.8	-0.4	-0.8	-0.9	-0.6	-0.5	-0.7	-1.1	0.3	-0.9	-0.2	-0.7	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.0	0.1	-0.1	-0.3	-0.9	-0.9	-0.4	-0.4	-0.7	0.2	-0.4	-0.9	-0.6	-0.6	-1.4	-0.2	-0.9	-1.0	-0.9
Allergy	0.3	0.6	3.2	-0.6	-0.6	0.3	0.7	1.0	0.3	0.4	0.8	-0.5	0.2	0.6	0.8	0.4	1.8	0.1	1.1	1.1	0.8
Pain all over the body in last month	0.3	0.4	0.9	0.3	0.4	1.0	0.3	0.5	0.9	-0.0	0.8	0.9	0.6	0.5	0.7	0.8	-0.1	0.5	0.7	0.4	0.3
Fluid intelligence score	0.3	0.6	1.1	0.6	0.6	0.8	0.8	0.7	1.0	0.5	0.9	1.0	1.0	0.8	0.9	0.8	0.2	0.8	0.7	0.7	0.7
Weight	0.3	1.3	2.6	1.0	1.0	0.5	1.6	1.5	1.1	1.5	0.8	0.9	1.4	1.5	1.1	0.2	0.8	0.9	1.3	0.9	1.6
Number of live births	0.3	0.4	0.9	0.9	0.9	0.5	0.5	0.3	0.6	0.7	0.4	0.9	0.7	0.4	0.5	0.3	-0.2	1.0	0.2	0.4	0.4
Medication: Cholesterol lowering	0.3	0.5	1.7	0.9	0.8	0.6	0.6	0.4	0.6	0.8	0.5	1.0	0.7	0.3	0.7	0.5	-0.1	1.3	0.2	0.7	0.6
Birth weight of first child	0.3	0.6	3.6	-1.4	-1.4	0.2	-0.3	-0.1	0.3	-1.9	0.5	-0.1	-0.6	-0.1	0.3	0.9	0.7	-0.1	0.3	0.2	-0.2
Blood clot in the leg (DVT)	0.3	0.4	1.0	0.6	0.8	0.9	0.3	0.1	0.6	-0.0	0.6	1.0	0.5	0.3	0.4	1.0	-0.2	1.0	0.0	0.5	0.3
Medication: Paracetamol	0.3	0.5	0.9	-0.1	-0.2	-0.7	-1.0	-0.8	-0.8	-0.2	-1.0	-0.3	-0.5	-0.9	-0.9	-0.9	-0.9	-0.4	-0.9	-0.9	-0.8
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.1	1.1	1.0	-0.4	-0.2	-0.3	-0.2	0.8	-0.7	0.6	0.4	-0.2	-0.5	-0.9	-1.1	0.0	-0.5	-0.8	-0.2
Migraine (self-reported)	0.3	0.4	2.3	-1.1	-1.0	0.4	-0.3	-0.2	0.2	-1.5	0.6	-0.2	-0.4	0.2	0.1	1.1	0.9	-0.4	0.3	0.3	-0.2
Illnesses of siblings: Diabetes	0.3	0.4	1.0	-0.1	0.3	0.7	0.6	0.7	0.7	-0.1	0.9	0.2	0.4	0.8	0.7	0.9	1.0	0.3	0.9	0.8	0.6
Osteoporosis (self-reported)	0.3	0.3	0.8	0.8	0.7	-0.3	-0.4	-0.4	-0.5	0.8	-0.7	-0.0	0.1	-0.3	-0.6	-0.8	-0.9	-0.3	-0.6	-0.7	-0.4
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.9	-0.6	-0.5	-0.8	-0.5	-0.6	-0.8	-0.4	-0.5	-0.9	-0.7	-0.5	-0.6	-0.5	0.1	-0.7	-0.6	-0.4	-0.5
Illnesses of father: High blood pressure	0.3	0.3	0.7	-0.6	-0.8	-0.4	-0.7	-0.6	-0.4	-0.8	-0.4	-0.6	-0.7	-0.5	-0.5	-0.2	-0.3	-0.6	-0.5	-0.5	-0.7
Diastolic blood pressure, automated reading	0.3	0.8	1.9	-0.5	-0.4	0.7	1.0	1.1	0.9	-0.4	1.1	0.1	0.5	1.1	1.0	1.0	1.4	0.2	1.3	1.0	0.9
Depression (Nagel 2018)	0.2	0.2	1.3	0.4	0.3	-0.2	-0.3	0.2	-0.4	0.6	-0.8	-0.2	0.1	-0.3	-0.5	-1.1	-0.5	-0.5	0.0	-0.7	-0.3
Neuroticism (Nagel 2018)	0.2	0.5	1.6	1.1	1.1	-0.6	0.1	0.0	-0.4	1.2	-0.8	0.2	0.5	-0.1	-0.5	-1.2	-0.6	0.2	-0.4	-0.6	0.1
Alzheimer’s Disease (in mother)	0.2	0.2	0.6	-0.5	-0.4	0.4	0.5	0.4	0.4	-0.5	0.7	0.1	0.2	0.5	0.6	0.7	0.8	0.1	0.6	0.6	0.5
Alzheimer’s Disease (in father)	0.2	0.2	0.5	-0.5	-0.6	0.3	0.3	0.4	0.2	-0.4	0.4	-0.3	-0.1	0.4	0.3	0.6	0.7	-0.3	0.6	0.4	0.3
Ovarian Cancer	0.2	0.3	1.0	0.0	0.1	0.2	0.6	0.6	0.4	0.3	0.6	0.1	0.4	0.5	0.6	0.4	1.0	0.5	0.6	0.7	0.8
Triglycerides	0.2	0.3	1.8	0.5	0.6	-0.3	-0.4	-0.5	-0.5	0.1	-0.6	0.1	-0.2	-0.6	-0.6	-0.6	-1.3	0.1	-0.8	-0.6	-0.4
Smoking Status	0.2	0.4	1.5	0.9	0.8	-0.1	0.9	0.6	0.1	1.2	0.1	0.0	0.6	0.8	0.2	-0.2	0.6	0.3	0.3	0.4	0.8
Allergy or Eczema	0.2	0.6	4.0	0.6	0.4	0.2	-0.7	-1.0	0.2	-0.8	-0.2	1.0	-0.1	-0.5	-0.4	0.4	-2.0	0.3	-1.0	-0.8	-0.8
Hypothyroidism (self reported)	0.2	0.5	1.6	-1.0	-0.8	-0.8	-0.6	-0.3	-0.7	-0.6	-0.6	-1.1	-0.7	-0.4	-0.6	-0.7	0.1	-1.3	-0.1	-0.7	-0.5
Neuroticism	0.2	0.4	1.3	0.2	0.3	-0.9	-0.3	-0.4	-0.8	0.3	-0.9	-0.6	-0.3	-0.4	-0.9	-1.1	-0.5	-0.5	-0.7	-0.8	-0.3
Average weekly spirits intake	0.2	0.2	0.6	-0.1	-0.1	-0.7	-0.3	-0.4	-0.4	-0.2	-0.7	-0.2	-0.4	-0.5	-0.6	-0.8	-0.7	-0.3	-0.6	-0.7	-0.4
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	0.2	0.3	-0.3	0.6	0.6	0.1	0.7	0.1	-0.1	0.4	0.7	0.1	-0.3	0.6	-0.1	0.5	0.2	0.7
Medication for hormone replacement therapy	0.2	0.3	0.4	0.5	0.4	0.4	0.6	0.5	0.6	0.5	0.6	0.5	0.5	0.5	0.6	0.4	0.2	0.7	0.5	0.6	0.6
Severe depression (siblings)	0.2	0.2	1.6	-0.6	-0.5	-0.1	0.5	0.5	0.2	-0.3	0.4	-0.2	0.0	0.5	0.4	0.2	1.3	0.1	0.6	0.5	0.6
Hand grip strength (right)	0.2	0.7	1.2	-0.1	-0.4	-0.7	-0.9	-0.9	-0.8	-0.2	-1.0	-0.4	-0.6	-0.9	-1.0	-1.0	-1.1	-0.7	-1.0	-1.1	-1.0
Supplements: Glucosamine	0.2	0.2	1.0	0.6	0.4	0.4	0.2	0.0	0.5	0.2	0.3	0.9	0.5	0.2	0.4	0.4	-1.0	0.5	-0.0	0.0	0.1
Past tobacco smoking	0.2	0.3	1.2	-0.3	-0.2	1.0	-0.3	0.0	0.8	-0.8	0.7	0.8	0.2	0.1	0.6	1.1	-0.4	0.3	0.4	0.2	-0.2
Had menopause	0.2	0.3	1.1	0.2	-0.0	-0.5	-0.5	-0.1	-0.6	0.4	-0.7	-0.3	-0.2	-0.6	-0.5	-1.0	-0.6	-0.4	-0.2	-0.7	-0.4
Medication: Simvastatin	0.2	0.3	0.9	0.7	0.6	0.1	0.6	0.4	0.3	0.9	0.3	0.4	0.5	0.4	0.5	0.1	0.2	0.8	0.2	0.5	0.7
Illnesses of siblings	0.2	0.3	1.5	1.0	0.6	0.2	-0.1	-0.4	0.1	0.6	-0.2	0.9	0.4	-0.2	-0.0	0.0	-1.2	0.6	-0.6	-0.3	-0.2
Neuroticism score	0.2	0.5	2.1	0.9	0.9	-0.9	0.3	0.1	-0.4	1.2	-0.8	0.1	0.5	0.0	-0.5	-1.4	-0.5	0.1	-0.4	-0.6	0.3
Alcohol intake versus 10 years previously	0.2	0.3	0.8	0.8	0.9	0.2	0.8	0.6	0.5	0.8	0.3	0.6	0.7	0.8	0.3	0.1	0.1	0.4	0.4	0.3	0.8
Noisy workplace	0.2	0.3	1.0	-1.0	-1.0	-0.5	-0.1	-0.2	-0.2	-0.9	-0.1	-0.6	-0.5	-0.1	-0.2	-0.0	0.6	-0.6	-0.0	-0.1	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.4	-0.2	-0.2	-0.6	-0.9	-0.8	-0.5	-0.7	-0.8	-0.3	-0.5	-0.5	-1.0	-0.7	-1.0	-1.0	-0.7	-1.2	-0.9
Standing height	0.2	2.1	3.8	-0.0	-0.4	-1.5	-1.7	-1.6	-1.5	-0.3	-1.8	-0.7	-1.1	-1.6	-1.7	-1.7	-1.9	-1.1	-1.8	-1.9	-1.6
Length of working week for main job	0.2	0.2	0.9	0.6	0.5	0.1	0.5	0.5	0.2	0.9	0.0	0.3	0.6	0.4	0.2	-0.4	0.0	0.3	0.3	0.1	0.5
Tense / ‘highly strung’	0.2	0.3	1.4	-0.8	-0.7	-0.3	0.5	0.5	0.2	-0.4	0.3	-0.2	0.1	0.5	0.3	0.0	1.2	-0.2	0.6	0.3	0.6
Hair/balding pattern: Pattern 4	0.2	0.5	2.8	-1.1	-1.4	0.0	0.2	0.2	-0.1	-0.5	0.5	-0.6	-0.4	-0.1	0.5	0.6	1.7	0.2	0.3	0.9	0.3
Headache pain in last month	0.2	0.3	1.1	-0.5	-0.5	-1.0	-0.2	-0.2	-0.6	-0.2	-0.7	-0.6	-0.4	-0.2	-0.6	-1.1	0.2	-0.8	-0.3	-0.7	-0.1
High blood pressure (siblings)	0.2	0.3	0.7	0.8	0.9	0.3	0.5	0.6	0.4	0.8	0.2	0.5	0.7	0.4	0.3	-0.1	0.1	0.6	0.4	0.2	0.5
Worry too long after embarrassment	0.2	0.3	1.3	-0.1	-0.1	-1.0	-0.0	-0.2	-0.7	0.4	-0.7	-0.7	-0.2	-0.4	-0.5	-1.1	-0.0	-0.4	-0.5	-0.4	-0.1
Age at first live birth	0.2	0.3	2.1	-0.8	-0.7	0.3	-0.6	-0.6	0.2	-1.4	0.2	0.2	-0.4	-0.4	-0.0	0.8	-0.0	0.0	-0.3	-0.1	-0.6
Qualifications: College or University degree	0.2	0.8	2.1	-0.4	-0.8	-1.1	-0.9	-0.6	-0.8	-0.3	-1.1	-0.6	-0.6	-0.9	-0.9	-1.5	-0.8	-0.9	-0.7	-1.2	-0.9
Emphysema/chronic bronchitis	0.2	0.2	0.8	0.8	0.7	-0.0	-0.4	-0.3	-0.3	0.4	-0.5	0.3	0.1	-0.4	-0.4	-0.5	-0.9	0.2	-0.5	-0.4	-0.4
Medication for pain relief, constipation, heartburn	0.2	0.4	2.5	0.8	0.7	0.5	-0.6	-0.7	-0.1	0.2	-0.3	0.5	0.1	-0.6	-0.3	0.1	-1.6	0.2	-0.7	-0.4	-0.7
Medication: Ibuprofen	0.2	0.2	0.6	-0.8	-0.6	-0.6	0.1	-0.0	-0.3	-0.7	-0.1	-0.7	-0.5	0.1	-0.3	-0.2	0.7	-0.5	0.0	-0.1	0.1
Chest pain or discomfort	0.2	0.3	0.9	1.0	0.7	-0.1	-0.1	-0.1	0.1	0.8	-0.4	0.9	0.6	-0.2	-0.0	-0.5	-1.0	0.6	-0.3	-0.4	-0.0
Had major operations	0.2	0.2	0.8	-0.8	-0.6	0.1	0.3	0.1	0.4	-0.9	0.6	0.1	-0.1	0.3	0.5	0.6	0.4	0.1	0.3	0.3	0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.9	0.6	0.7	-0.6	0.3	0.3	-0.1	0.9	-0.3	0.1	0.5	0.3	-0.1	-0.9	-0.2	-0.1	-0.0	-0.4	0.4
Smoking status: Previous	0.2	0.3	1.1	-0.3	-0.3	-1.0	0.5	0.2	-0.7	0.4	-0.4	-1.0	-0.3	0.2	-0.4	-0.9	1.0	-0.5	-0.1	-0.0	0.4
Long-standing illness, disability or infirmity	0.2	0.3	0.8	0.6	0.5	0.2	0.6	0.8	0.5	0.9	0.4	0.4	0.7	0.6	0.5	-0.1	0.4	0.3	0.8	0.3	0.7
Mineral and other dietary supplements	0.2	0.3	0.7	-0.8	-0.7	-0.3	-0.5	-0.4	-0.6	-0.8	-0.3	-0.8	-0.7	-0.4	-0.6	-0.1	0.6	-0.7	-0.3	-0.2	-0.5
Medication: Aspirin	0.2	0.3	0.6	0.3	0.2	0.2	0.7	0.7	0.5	0.5	0.6	0.3	0.5	0.6	0.7	0.3	0.8	0.6	0.6	0.7	0.8
Illnesses of father: None of the above (group 1)	0.2	0.3	1.6	-0.9	-0.9	-0.3	0.4	0.2	-0.3	-0.2	0.2	-0.8	-0.4	0.0	0.3	0.2	1.3	-0.1	0.2	0.6	0.4
Smoking status: Current	0.2	0.4	1.6	1.3	1.1	0.6	0.0	0.0	0.3	0.8	0.1	0.9	0.6	0.1	0.1	0.2	-0.8	0.7	-0.1	0.0	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.9	-0.7	-0.7	-0.4	-0.8	-0.8	-0.5	-1.0	-0.5	-0.4	-0.7	-0.8	-0.5	-0.3	-0.5	-0.5	-0.7	-0.6	-0.9
Miserableness	0.2	0.4	2.2	1.5	1.3	0.2	0.2	0.0	0.0	1.1	-0.2	0.7	0.6	0.1	-0.1	-0.3	-1.0	0.5	-0.3	-0.1	0.2
Mother’s age at death	0.2	0.3	1.5	-0.8	-0.8	0.4	-0.4	-0.1	0.2	-1.2	0.4	0.2	-0.4	-0.4	0.3	0.7	0.1	0.2	0.2	0.2	-0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.7	-0.6	-0.7	-0.8	-0.2	-0.3	-0.6	-0.3	-0.4	-0.6	-0.5	-0.4	-0.3	-0.5	0.0	-0.4	-0.4	-0.3	-0.2
High cholesterol (Self-reported)	0.2	0.4	1.6	0.8	1.0	-0.4	0.8	0.6	0.2	1.3	0.1	0.2	0.7	0.7	0.2	-0.5	0.2	0.2	0.3	0.1	0.8
Medication: Paracetamol	0.2	0.3	0.7	-0.3	-0.2	-0.4	-0.8	-0.6	-0.7	-0.3	-0.7	-0.3	-0.5	-0.7	-0.7	-0.5	-0.5	-0.3	-0.7	-0.6	-0.6
Ever smoked	0.2	0.4	2.0	1.3	1.2	-0.0	0.6	0.4	-0.0	1.4	-0.1	0.3	0.6	0.4	-0.0	-0.5	0.1	0.6	0.0	0.2	0.6
Irritability	0.2	0.3	0.9	0.9	0.9	-0.5	0.3	0.1	-0.2	0.9	-0.5	0.3	0.4	0.1	-0.3	-0.9	-0.4	0.3	-0.3	-0.4	0.3
Commuting to job workplace: Cycle	0.2	0.2	1.0	-0.1	-0.2	0.8	-0.3	-0.1	0.5	-0.8	0.5	0.6	-0.1	-0.1	0.3	1.0	-0.1	0.4	0.2	0.3	-0.2
Basal cell carcinoma (self-reported)	0.2	0.2	1.0	1.0	1.0	0.1	0.3	0.2	0.2	0.8	0.0	0.4	0.5	0.5	0.0	-0.1	-0.6	0.2	0.1	-0.1	0.3
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.6	0.4	0.5	0.2	0.7	0.5	0.6	0.4	0.5	0.4	0.6	0.7	0.5	0.2	0.4	0.2	0.5	0.3	0.6
Crohns Disease (2017)	0.1	0.3	0.9	-0.3	-0.3	0.3	-1.0	-0.9	-0.5	-0.7	-0.1	-0.3	-0.6	-0.7	-0.3	0.6	-0.6	-0.2	-0.7	-0.1	-0.9
Reaction Time	0.1	0.1	0.8	0.5	0.3	-0.3	0.1	0.2	-0.4	0.9	-0.4	-0.4	-0.1	-0.2	-0.3	-0.7	0.2	0.1	-0.1	0.1	0.1
Crohns Disease (2012)	0.1	0.2	0.9	-0.4	-0.2	0.6	-0.8	-0.5	0.1	-0.9	0.2	0.3	-0.2	-0.4	-0.0	0.7	-0.6	-0.1	-0.1	-0.2	-0.7
HDL Cholesterol	0.1	0.2	0.4	0.1	0.2	0.6	0.4	0.4	0.6	-0.2	0.5	0.5	0.4	0.4	0.5	0.6	0.3	0.4	0.5	0.4	0.4
Lupus	0.1	0.1	0.5	-0.4	-0.5	0.1	-0.2	0.2	0.1	-0.2	0.2	0.1	0.0	0.1	0.4	0.3	0.7	0.2	0.3	0.4	0.2
Rheumatoid Arthritis	0.1	0.1	0.6	0.0	-0.0	-0.1	-0.1	-0.2	0.3	-0.1	-0.1	0.7	0.2	-0.3	0.2	-0.1	-0.4	0.5	-0.2	-0.2	-0.2
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.4	-0.5	-0.4	0.1	-0.2	0.1	-0.0	-0.0	0.3	-0.4	-0.1	-0.0	0.2	0.3	0.7	-0.2	0.3	0.3	0.0
Blood White Count	0.1	0.9	3.4	1.8	1.7	-0.1	-0.4	-0.4	-0.4	1.6	-0.9	0.6	0.3	-0.5	-0.6	-0.9	-1.7	0.5	-0.9	-0.6	-0.3
Heel T-Score	0.1	0.8	3.6	-1.7	-1.5	0.1	-0.5	-0.6	-0.4	-1.9	0.2	-0.8	-1.2	-0.5	-0.2	0.9	-0.5	-0.7	-0.3	-0.1	-0.6
Waist Hip Ratio (WHR)	0.1	0.7	2.3	0.1	-0.2	0.2	1.0	1.1	0.5	1.0	0.6	-0.0	0.6	1.0	0.9	0.2	1.5	0.3	1.0	1.0	1.1
Systolic Blood Pressure	0.1	0.4	2.0	-1.0	-1.0	-0.3	0.5	0.5	-0.0	-0.2	0.5	-0.8	-0.1	0.4	0.5	0.3	1.4	-0.4	0.7	0.6	0.5
Tanning	0.1	1.1	4.2	0.7	0.5	-0.6	-1.2	-1.3	-1.0	0.0	-1.2	0.0	-0.6	-1.2	-1.2	-0.8	-2.0	-0.3	-1.6	-1.2	-1.2
Hand grip strength (left)	0.1	0.3	0.8	0.1	-0.1	-0.4	-0.6	-0.7	-0.4	-0.1	-0.7	0.0	-0.3	-0.6	-0.6	-0.6	-0.9	-0.1	-0.8	-0.7	-0.6
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.6	0.6	0.6	0.3	0.1	0.1	0.4	0.2	-0.1	0.8	0.5	0.1	-0.0	-0.2	-0.8	0.3	0.1	-0.3	0.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.3	0.2	0.4	0.0	0.4	0.3	0.4	0.1	0.3	0.2	0.4	0.6	0.2	0.0	-0.0	-0.1	0.3	-0.0	0.4
Systolic blood pressure, automated reading	0.1	0.3	0.9	-0.8	-0.8	-0.0	0.5	0.6	0.4	-0.4	0.6	-0.2	0.1	0.4	0.6	0.1	0.9	-0.2	0.9	0.4	0.4
Diabetes (father)	0.1	0.1	0.6	-0.0	0.1	-0.0	-0.5	-0.3	0.0	-0.4	-0.2	0.3	0.0	-0.2	-0.2	-0.1	-0.8	-0.2	-0.2	-0.5	-0.5
Diabetes (mother)	0.1	0.1	0.3	0.0	0.1	0.1	0.3	0.3	0.4	-0.1	0.2	0.5	0.3	0.3	0.3	0.1	-0.2	0.3	0.2	0.0	0.3
Leg fat-free mass (left)	0.1	0.4	1.4	1.1	1.2	0.3	0.6	0.6	0.5	1.1	0.2	0.8	0.9	0.7	0.3	-0.1	-0.4	0.5	0.4	0.1	0.6
Average weekly fortified wine intake	0.1	0.1	0.5	-0.1	-0.3	0.6	-0.0	-0.1	0.4	-0.5	0.4	0.6	0.1	-0.2	0.4	0.7	-0.2	0.7	0.0	0.3	-0.1
Maternal smoking around birth	0.1	0.2	1.0	0.6	0.4	-0.2	0.3	0.3	-0.2	1.0	-0.3	0.2	0.3	-0.1	0.1	-0.7	-0.4	0.4	-0.1	-0.0	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	0.0	-0.0	-0.3	0.3	0.3	-0.2	0.5	-0.2	-0.4	0.1	0.3	-0.1	-0.5	0.3	-0.5	0.3	-0.1	0.3
Serious illness, injury or assault to yourself	0.1	0.1	0.4	-0.3	-0.0	-0.3	-0.3	-0.2	-0.4	-0.3	-0.4	-0.7	-0.4	-0.1	-0.6	-0.4	0.2	-0.7	-0.1	-0.3	-0.3
Leg predicted mass (left)	0.1	0.5	1.4	1.1	1.2	0.4	0.6	0.6	0.6	1.1	0.2	0.8	0.9	0.7	0.3	-0.0	-0.3	0.5	0.4	0.1	0.6
Forced vital capacity (FVC)	0.1	0.6	2.0	0.5	0.3	-0.5	-0.9	-0.8	-0.5	-0.0	-0.9	0.1	-0.3	-0.7	-0.9	-0.8	-1.4	-0.4	-0.9	-1.0	-0.8
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.7	-0.8	-0.7	-0.4	-0.0	-0.2	-0.2	-0.8	0.1	-0.6	-0.5	0.0	-0.1	0.2	0.5	-0.5	0.0	0.0	-0.0
Time employed in main current job	0.1	0.2	0.4	0.2	0.6	0.6	0.4	0.4	0.3	-0.0	0.5	0.1	0.3	0.4	0.3	0.6	0.4	0.3	0.4	0.5	0.3
Worrier / anxious feelings	0.1	0.2	0.6	0.2	0.0	-0.5	-0.5	-0.5	-0.5	0.2	-0.6	0.1	-0.2	-0.7	-0.4	-0.7	-0.8	0.2	-0.7	-0.5	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.5	0.6	0.6	0.1	0.3	0.3	0.0	0.7	-0.1	0.1	0.3	0.3	-0.1	-0.1	0.3	0.2	0.1	0.2	0.3
Impedance of arm (left)	0.1	0.3	0.8	0.2	-0.2	0.0	-0.8	-0.8	-0.3	-0.4	-0.4	0.2	-0.4	-0.7	-0.4	0.1	-0.9	0.1	-0.8	-0.4	-0.7
Glaucoma (self-reported)	0.1	0.1	0.4	0.4	0.5	0.1	0.5	0.4	0.1	0.6	0.2	0.0	0.3	0.3	0.2	0.1	0.4	0.3	0.2	0.4	0.4
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.9	0.4	0.5	-0.1	-0.3	-0.4	-0.1	-0.2	-0.3	0.3	0.1	-0.1	-0.4	-0.2	-0.9	-0.1	-0.4	-0.6	-0.3
Arm fat-free mass (right)	0.1	0.3	1.5	0.8	0.7	-0.4	0.4	0.4	-0.0	1.2	-0.4	0.2	0.6	0.3	-0.1	-0.9	-0.3	-0.1	0.2	-0.3	0.4
Shortness of breath walking on level ground	0.1	0.1	0.3	0.3	0.3	0.1	0.2	0.3	0.3	0.3	0.0	0.4	0.2	0.0	0.2	-0.2	-0.1	0.6	0.1	0.1	0.3
Eye problems/disorders: None of the above	0.1	0.1	0.4	-0.0	0.1	0.2	-0.2	-0.5	0.0	-0.6	-0.0	0.2	-0.1	-0.2	-0.3	0.2	-0.6	-0.1	-0.4	-0.3	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.5	-0.0	-0.0	0.5	-0.7	-0.4	-0.2	-0.3	-0.2	0.2	-0.2	-0.6	-0.2	0.3	-0.6	-0.0	-0.3	-0.2	-0.6
Arm predicted mass (right)	0.1	0.3	1.4	0.8	0.8	-0.6	0.1	0.2	-0.3	1.2	-0.6	0.0	0.4	0.0	-0.4	-1.2	-0.7	-0.3	-0.1	-0.6	0.1
Suffer from ‘nerves’	0.1	0.1	0.4	0.6	0.5	0.2	-0.2	-0.1	0.0	0.3	-0.2	0.6	0.3	-0.3	-0.1	-0.1	-0.5	0.6	-0.3	-0.1	-0.1
Family relationship satisfaction	0.1	0.2	1.0	-0.2	-0.3	0.7	-0.1	-0.0	0.3	-0.6	0.5	0.3	-0.0	-0.0	0.4	1.0	0.1	0.3	0.2	0.4	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.8	-0.3	-0.2	0.4	0.2	-0.1	-0.1	-0.2	0.4	-0.4	-0.3	0.1	0.2	0.9	0.3	0.1	-0.1	0.6	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.6	0.6	0.4	-0.1	0.2	0.3	0.2	0.8	-0.2	0.5	0.4	-0.0	0.2	-0.5	-0.3	0.5	0.1	-0.1	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.7	-0.3	-0.2	-0.7	-0.4	-0.5	-0.5	-0.3	-0.6	-0.5	-0.4	-0.2	-0.7	-0.5	-0.4	-0.8	-0.4	-0.7	-0.4
Whole body fat-free mass	0.1	0.3	1.2	0.9	1.0	-0.0	0.5	0.5	0.3	1.1	-0.1	0.4	0.7	0.5	0.1	-0.5	-0.3	0.2	0.3	-0.1	0.5
Leg fat-free mass (right)	0.1	0.5	1.9	1.3	1.4	0.2	0.5	0.5	0.4	1.3	-0.0	0.8	0.9	0.6	0.1	-0.3	-0.7	0.4	0.2	-0.1	0.5
Average weekly red wine intake	0.1	0.1	0.7	-0.6	-0.8	-0.4	-0.3	0.1	-0.2	-0.1	-0.2	-0.4	-0.2	-0.3	-0.0	-0.5	0.6	-0.3	0.1	-0.1	-0.2
Leg predicted mass (right)	0.1	0.5	1.9	1.3	1.4	0.2	0.5	0.5	0.4	1.3	-0.1	0.8	0.9	0.6	0.1	-0.4	-0.7	0.4	0.2	-0.1	0.5
Commuting to job workplace: Public transport	0.1	0.2	0.4	-0.5	-0.4	-0.1	-0.4	-0.5	-0.5	-0.4	-0.2	-0.6	-0.6	-0.4	-0.3	0.2	0.0	-0.4	-0.4	-0.0	-0.4
Eye problems/disorders: Glaucoma	0.1	0.1	0.4	-0.1	-0.1	0.1	0.4	0.5	0.3	0.1	0.4	0.2	0.3	0.4	0.5	0.2	0.6	0.2	0.5	0.4	0.4
Medication: Blood pressure	0.1	0.3	0.6	0.3	0.2	-0.5	-0.6	-0.6	-0.6	0.4	-0.7	-0.2	-0.2	-0.6	-0.5	-0.7	-0.8	-0.3	-0.7	-0.6	-0.5
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.4	-0.4	-0.3	-0.3	0.0	0.1	-0.4	0.1	-0.3	-0.7	-0.2	-0.0	-0.2	-0.4	0.2	-0.6	0.1	-0.1	0.0
Medication: Lisinopril	0.1	0.1	0.2	0.3	0.1	-0.3	0.3	0.3	0.1	0.5	-0.2	0.2	0.3	0.2	-0.0	-0.5	0.4	0.1	0.2	-0.1	0.4
Basal metabolic rate	0.1	0.3	1.3	0.9	0.9	0.0	0.7	0.6	0.4	1.1	0.0	0.5	0.8	0.7	0.2	-0.4	-0.2	0.3	0.4	0.0	0.6
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.6	0.5	0.2	0.2	-0.1	-0.1	0.2	0.3	0.1	0.7	0.3	-0.3	0.3	0.1	-0.8	0.7	-0.2	0.0	-0.1
Age started oral contraceptive pill	0.1	0.1	0.3	-0.2	-0.4	-0.4	0.0	0.3	-0.0	0.1	-0.1	-0.1	0.1	-0.0	0.1	-0.6	0.3	-0.3	0.4	-0.2	0.1
Worry (Nagel 2018)	0.0	0.0	0.1	-0.2	-0.1	-0.1	-0.4	-0.2	-0.2	-0.3	-0.3	0.1	-0.1	-0.3	-0.3	-0.2	-0.2	-0.1	-0.1	-0.3	-0.3
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.2	0.2	-0.0	0.2	0.1	0.1	0.4	0.0	0.3	0.4	0.4	0.2	0.3	0.2	-0.2	0.1	0.2	0.0	0.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Height	0.0	0.4	1.0	0.2	-0.2	-0.9	-0.6	-0.7	-0.7	0.3	-0.9	-0.3	-0.4	-0.8	-0.7	-1.0	-0.7	-0.1	-0.9	-0.7	-0.6
Lung FVC	0.0	0.0	0.1	-0.3	-0.1	0.2	0.2	0.1	0.1	-0.3	0.3	-0.1	-0.0	0.2	0.1	0.3	0.3	-0.1	0.2	0.2	0.1
Hair Pigment	0.0	1.2	4.3	1.8	1.7	0.8	1.0	0.8	0.6	2.1	0.5	1.1	1.2	0.6	0.8	0.3	-0.3	1.6	0.3	0.9	0.9
Impedance of leg (right)	0.0	0.1	0.6	-0.4	-0.8	-0.2	-0.2	-0.2	-0.3	-0.3	-0.1	-0.3	-0.4	-0.3	-0.0	0.1	0.3	-0.0	-0.1	0.1	-0.2
Taking other prescription medications	0.0	0.1	0.3	-0.1	-0.1	0.0	0.4	0.4	0.2	0.1	0.2	0.0	0.2	0.3	0.3	0.0	0.6	0.1	0.4	0.2	0.3
Age when periods started (menarche)	0.0	0.0	0.2	0.2	0.1	-0.1	-0.3	-0.1	-0.3	0.2	-0.2	-0.1	-0.2	-0.4	-0.2	-0.3	-0.1	0.2	-0.2	-0.0	-0.2
Impedance of leg (left)	0.0	0.0	0.1	0.2	-0.2	-0.2	-0.2	-0.2	-0.3	0.3	-0.3	-0.0	-0.1	-0.3	-0.1	-0.3	-0.2	0.0	-0.3	-0.1	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.2	0.2	0.4	0.0	0.2	0.1	0.2	-0.1	-0.0	0.4	0.1	0.1	-0.1	-0.0	-0.0	0.2	0.0	-0.1	0.1
Impedance of arm (right)	0.0	0.1	0.5	0.5	0.1	0.4	-0.4	-0.4	0.1	-0.1	-0.0	0.6	-0.0	-0.4	-0.1	0.4	-0.7	0.5	-0.4	-0.1	-0.3
Trunk fat-free mass	0.0	0.2	0.8	0.5	0.5	-0.5	0.1	0.2	-0.2	0.7	-0.4	-0.1	0.2	0.1	-0.3	-0.9	-0.4	-0.3	-0.0	-0.5	0.1
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.3	0.5	0.5	0.2	-0.2	-0.1	0.3	0.0	0.0	0.4	0.2	0.2	-0.1	0.1	-0.6	0.0	-0.0	-0.3	-0.1
Trunk predicted mass	0.0	0.2	0.9	0.4	0.4	-0.6	0.1	0.1	-0.2	0.6	-0.5	-0.2	0.1	0.1	-0.4	-0.9	-0.4	-0.4	-0.1	-0.5	0.1
Peak expiratory flow (PEF)	0.0	0.1	0.3	0.5	0.4	-0.2	-0.2	-0.2	-0.3	0.6	-0.4	0.0	0.1	-0.2	-0.3	-0.5	-0.5	0.1	-0.3	-0.3	-0.2
Exposure to tobacco smoke outside home	0.0	0.0	0.0	0.0	0.0	0.1	0.1	-0.0	-0.0	-0.2	-0.0	0.1	-0.0	-0.0	-0.0	0.1	-0.0	0.1	-0.1	0.0	-0.1
Alcohol intake frequency.	0.0	0.0	0.1	0.0	0.1	-0.1	0.0	0.2	-0.0	0.3	-0.1	-0.1	0.1	0.1	-0.1	-0.2	0.2	-0.0	0.2	-0.0	0.1
Comparative height size at age 10	0.0	0.3	1.2	1.0	0.8	0.2	0.2	0.2	0.2	1.1	-0.1	0.7	0.5	0.1	0.2	-0.2	-0.7	0.6	-0.0	0.0	0.3
Friendships satisfaction	0.0	0.1	0.3	-0.2	-0.4	-0.1	-0.1	-0.3	-0.0	-0.6	0.0	0.2	-0.2	-0.3	0.0	0.2	-0.1	0.3	-0.3	0.0	-0.2
Medication for cholesterol	0.0	0.1	0.2	-0.4	-0.5	0.3	-0.1	0.0	0.1	-0.5	0.2	0.1	-0.2	-0.2	0.2	0.4	0.2	0.2	0.1	0.2	-0.1
Whole body water mass	0.0	0.3	1.2	0.9	0.9	-0.1	0.5	0.6	0.3	1.1	-0.1	0.4	0.7	0.5	0.1	-0.5	-0.2	0.2	0.3	-0.1	0.5
Arm fat-free mass (left)	0.0	0.2	0.9	0.5	0.5	-0.4	0.4	0.5	-0.0	0.9	-0.3	0.0	0.4	0.3	-0.0	-0.9	-0.1	-0.1	0.3	-0.2	0.4
Impedance of whole body	0.0	0.2	0.4	0.0	-0.4	-0.1	-0.6	-0.6	-0.4	-0.3	-0.4	0.0	-0.4	-0.7	-0.3	-0.1	-0.6	0.0	-0.6	-0.3	-0.6
Arm predicted mass (left)	0.0	0.2	0.8	0.4	0.4	-0.4	0.6	0.7	0.1	0.9	-0.1	0.0	0.5	0.5	0.1	-0.7	0.2	-0.0	0.4	-0.0	0.6

Hub : Genes

KLRC2

Models

Trait associations