TWAS hub - KPNA5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Lung	0.0975	0.0393	2.7e-03	-0.003	NA	0.016	NA	0.002	5.8e-01	NA	2.1e-02	NA	2.3e-01
2	GTEx	Nerve Tibial	0.0750	0.0358	8.3e-03	0.018	NA	0.012	NA	0.016	1.8e-02	NA	4.8e-02	NA	2.3e-02
3	GTEx	Thyroid	0.1060	0.0370	2.1e-04	0.057	NA	0.058	NA	0.071	3.3e-05	NA	2.9e-05	NA	4.4e-06
4	METSIM	Adipose	0.0396	0.0179	2.8e-03	-0.001	0.001	0.003	0.002	-0.002	6.5e-01	2.1e-01	8.9e-02	0.13000	7.3e-01
5	YFS	Blood	0.0321	0.0142	1.2e-03	0.015	0.009	0.006	0.014	0.012	7.3e-06	4.0e-04	4.6e-03	0.00002	5.9e-05
6	TCGA	Bladder Urothelial Carcinoma	0.0390	0.0210	6.6e-03	0.011	0.011	0.026	NA	0.011	3.5e-02	3.8e-02	2.7e-03	NA	3.9e-02
7	TCGA	Breast Invasive Carcinoma	0.0522	0.0223	5.6e-05	0.021	0.021	0.016	NA	0.017	2.9e-05	3.0e-05	2.1e-04	NA	1.5e-04
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0727	0.0321	1.2e-03	0.022	0.011	0.006	NA	0.015	1.5e-03	1.7e-02	6.2e-02	NA	7.5e-03
9	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1060	0.0500	5.7e-03	0.014	0.021	0.032	NA	0.030	4.9e-02	2.1e-02	6.3e-03	NA	7.4e-03
10	TCGA	Prostate Adenocarcinoma	0.0811	0.0330	1.8e-04	0.064	0.045	0.044	NA	0.054	3.0e-07	1.7e-05	2.0e-05	NA	2.2e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Mouth/teeth dental problems: Dentures	3.3	5.6	12.0	-0.7	-2.7	-2.6	-0.5	3.5	1.4	2.4	3.0	2.3	2.6
Medication: Aspirin	3.0	4.0	7.8	-0.6	-1.1	-1.2	1.2	2.1	2.1	2.5	2.5	2.8	2.4
Depression (self-reported)	2.9	3.5	6.6	-0.9	-1.9	-1.6	-0.6	-2.6	-1.4	-2.2	-1.9	-2.5	-2.1
Medication: Atorvastatin	2.9	3.6	6.7	-1.3	-0.9	-1.0	2.2	1.8	2.2	2.1	2.0	2.6	2.1
Heart attack/myocardial infarction (self-reported)	2.7	3.4	7.1	-0.5	-1.6	-1.6	-0.6	1.5	1.4	2.3	2.4	2.7	2.5
Mean Putamen Volume	2.6	3.0	7.0	-0.1	-0.2	-0.1	-2.0	-2.0	-1.0	-2.6	-2.4	-1.6	-2.4
Severe depression (siblings)	2.6	3.0	6.3	-2.4	-1.0	-1.1	0.4	1.2	0.8	1.7	2.4	2.1	2.5
Heart attack	2.6	3.3	7.0	-0.8	-1.5	-1.5	-0.4	1.4	1.3	2.2	2.4	2.7	2.6
Medication: Blood pressure	2.6	4.7	11.7	-2.8	-3.4	-3.2	-1.3	0.9	1.9	0.7	1.8	1.8	1.8
Heart disease (mother)	2.6	3.2	11.3	-1.8	-0.9	-1.4	0.6	1.4	3.4	1.5	1.5	2.3	1.7
Medication: Aspirin	2.6	3.4	7.3	-0.1	-0.7	-0.8	1.5	2.1	2.0	2.3	2.2	2.7	2.1
Tense / ‘highly strung’	2.5	4.1	7.6	-0.9	-0.6	-0.9	-2.4	-2.3	-1.7	-2.2	-2.4	-2.8	-2.6
Pulse wave reflection index	2.5	3.1	11.3	1.5	-0.6	-0.1	0.0	1.4	1.6	2.2	1.9	3.4	2.1
Medication for cholesterol, blood pressure or diabetes	2.4	4.0	10.2	3.2	2.9	3.0	1.1	-0.2	-1.9	-0.4	-1.5	-1.4	-1.6
Number of treatments/medications taken	2.3	4.1	13.2	-1.7	-3.3	-3.6	-1.8	0.4	2.5	0.2	1.0	1.4	1.2
Mouth/teeth dental problems	2.3	3.5	5.9	1.2	2.4	2.4	0.4	-2.3	-1.6	-1.3	-1.9	-2.3	-1.8
Major Depression (MDD)	2.2	2.6	5.6	-1.5	-2.4	-2.2	-1.3	-1.2	-0.0	-2.0	-1.7	-0.8	-1.6
Prospective memory result	2.2	2.7	5.8	-0.7	-0.9	-1.3	0.4	1.5	2.4	1.4	2.1	2.2	2.1
Mouth/teeth dental problems: Mouth ulcers	2.2	3.4	8.6	-1.0	0.2	0.0	-1.3	-2.6	-2.0	-2.9	-2.3	-1.4	-2.3
Mean time to correctly identify matches	2.1	4.0	6.8	-2.4	-2.5	-2.6	-2.2	-2.2	0.6	-2.5	-1.6	-1.0	-1.5
Eye problems/disorders: Cataract	2.1	2.5	5.1	-0.7	-0.9	-1.6	1.1	2.2	2.3	1.2	1.8	1.4	1.8
Alcohol drinker status: Previous	2.1	2.3	6.5	0.2	-0.5	-0.4	-1.3	-1.7	-0.7	-2.1	-2.5	-1.3	-2.3
Irritable Bowel Disease (IBD)	2.0	4.7	11.0	1.1	2.9	3.2	2.0	-1.5	-3.3	-1.1	-1.5	-2.0	-1.6
Ulcerative Colitis (UC)	2.0	3.8	12.2	0.7	2.7	2.8	2.4	-0.0	-3.5	0.1	-0.3	-2.0	-0.6
Medication: Atenolol	2.0	2.5	4.5	-1.0	-1.9	-2.1	-0.4	1.3	1.7	1.5	1.8	1.4	1.8
Reaction Time	1.9	3.6	6.2	-1.9	-2.0	-2.4	-2.1	-2.5	0.9	-2.1	-1.7	-1.1	-1.5
Chronic bronchitis/emphysema (father)	1.9	2.2	8.9	1.5	-1.3	-0.7	-3.0	-1.6	-0.5	-0.8	-1.5	-1.0	-1.4
Medication: Ibuprofen	1.9	2.3	3.6	1.9	0.9	0.7	-1.7	-1.2	-1.4	-1.3	-1.9	-1.7	-1.9
Overall health rating	1.9	4.1	9.0	-1.7	-0.3	-0.3	-0.8	-2.1	-1.8	-3.0	-2.4	-3.0	-2.3
Smoking status: Current	1.9	3.0	6.8	-0.9	-1.9	-1.8	0.0	1.8	2.6	0.5	2.1	1.8	2.1
Worry (Nagel 2018)	1.8	3.8	7.1	-0.9	-1.1	-1.1	-2.1	-2.5	-1.4	-1.3	-2.6	-2.6	-2.7
Type 2 Diabetes (T2D) (2012)	1.8	2.1	3.4	-1.4	-1.6	-1.1	0.1	1.3	1.0	1.8	1.6	1.8	1.7
Ulcerative Colitis	1.8	2.5	12.5	0.6	1.3	1.8	1.3	-0.2	-3.5	-0.9	-0.7	-2.0	-0.9
Medication: Cholesterol lowering	1.8	2.8	10.0	-3.2	-1.8	-2.0	0.1	0.3	1.4	0.6	1.8	1.3	1.9
Body Mass Index (BMI) (2010)	1.7	2.4	5.2	-0.8	-2.0	-2.3	-0.1	1.2	2.1	1.5	1.6	0.9	1.6
Medication: Metformin	1.7	2.4	9.0	-3.0	-1.4	-1.7	-0.0	0.3	1.9	-0.0	1.1	1.8	1.5
Current tobacco smoking	1.7	2.8	5.3	-0.9	-1.6	-1.5	0.1	1.7	2.3	0.6	2.2	1.9	2.2
Birth weight of first child	1.7	3.1	9.5	-1.0	1.2	1.3	-1.3	-1.2	-2.9	-1.5	-1.2	-3.1	-1.5
Average weekly red wine intake	1.7	2.5	8.9	-0.7	-1.2	-1.1	-3.0	-1.7	-1.2	-1.9	-1.2	-0.9	-1.4
Noisy workplace	1.6	2.0	5.0	-0.2	0.1	-0.3	1.5	2.2	0.6	1.9	2.2	0.7	1.8
Medication: Amlodipine	1.6	2.2	7.1	-1.6	-2.7	-2.3	-0.4	0.9	1.0	1.6	1.2	0.7	1.1
Average weekly champagne plus white wine intake	1.6	2.1	3.7	0.3	0.4	0.3	-1.3	-1.9	-1.8	-1.8	-1.8	-1.6	-1.9
Alcohol drinker status: Never	1.6	1.9	5.8	-1.0	-0.6	-0.7	-1.9	-1.5	-0.4	-2.4	-1.6	-0.9	-1.5
Crohns Disease (2017)	1.5	3.2	6.2	1.0	2.4	2.5	0.8	-2.4	-1.4	-1.6	-2.0	-0.8	-1.7
Hearing difficulty/problems with background noise	1.4	2.2	5.1	-0.0	-1.9	-1.5	-1.7	-1.5	-0.8	-2.2	-1.2	-1.7	-1.1
Worry too long after embarrassment	1.4	2.3	5.3	-1.3	-0.7	-0.9	-1.2	-1.3	-0.2	-1.9	-2.3	-1.9	-2.1
Shortness of breath walking on level ground	1.4	1.6	4.5	-0.2	-1.7	-2.1	0.3	0.7	1.5	1.4	1.1	1.2	1.1
Ever taken oral contraceptive pill	1.4	1.6	3.0	0.9	1.0	0.7	1.1	1.7	0.7	1.5	1.5	1.4	1.5
High cholesterol (Self-reported)	1.4	2.5	8.5	-2.9	-2.3	-2.8	-0.4	-0.7	0.9	-1.1	0.2	-0.6	0.2
Illnesses of father: High blood pressure	1.4	1.8	4.7	-1.5	-2.0	-2.2	-1.6	-1.1	0.2	-1.4	0.2	0.7	0.4
Frequency of depressed mood in last 2 weeks	1.3	1.8	5.6	-0.7	0.3	-0.1	0.7	-1.6	-0.5	-2.4	-1.6	-2.1	-1.5
Hair/balding pattern: Pattern 2	1.3	1.7	3.2	0.2	1.2	0.7	0.2	-1.8	-1.0	-1.6	-1.8	-1.4	-1.7
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.7	5.1	2.3	0.8	0.7	-1.0	-0.7	-1.5	-0.7	-1.4	-1.4	-1.5
Medication: Seretide 50 evohaler	1.3	1.5	4.1	0.2	-0.6	-0.9	0.6	1.5	2.0	0.8	0.9	2.0	1.2
Financial situation satisfaction	1.3	1.6	3.5	1.9	1.5	1.1	1.8	1.1	0.7	1.3	1.0	0.8	0.9
Risk taking	1.3	1.9	4.9	0.9	1.8	2.2	1.7	0.3	-1.4	-0.4	-1.1	-1.6	-1.2
Schizophrenia (2014)	1.2	2.7	8.8	1.5	1.8	1.6	3.0	1.6	1.4	1.4	0.9	1.5	0.9
Triglycerides	1.2	2.0	7.2	-1.1	-2.2	-2.0	-2.7	-0.5	1.2	-0.3	-0.4	-0.8	-0.2
Smoking Status	1.2	2.9	7.4	-1.9	-2.7	-2.7	-0.5	0.9	1.8	0.4	1.5	1.3	1.6
Taking other prescription medications	1.2	1.8	6.4	-2.5	-1.4	-2.2	0.4	-0.8	0.6	-1.6	-0.3	-0.9	-0.2
Pulse rate	1.2	2.0	5.9	-0.3	0.6	0.3	-0.8	-1.4	-0.3	-2.4	-2.0	-1.7	-1.9
Medication: Lansoprazole	1.2	1.3	5.1	-1.2	-2.1	-2.2	-0.1	-0.5	0.5	-1.1	-0.5	-0.0	-0.5
Exposure to tobacco smoke at home	1.2	1.3	5.3	-2.3	-1.6	-1.7	-0.3	0.3	1.2	0.4	0.2	0.3	0.3
Medication: Ventolin 100micrograms inhaler	1.2	1.5	7.1	0.1	-1.4	-1.5	-0.2	-0.2	2.7	0.6	0.3	1.5	0.8
Pulse rate, automated reading	1.2	3.7	7.8	1.4	1.7	1.9	-0.0	-1.8	-1.4	-2.8	-2.6	-1.8	-2.5
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	8.8	-0.2	3.0	2.8	0.8	-0.7	-2.2	-0.4	-0.6	-1.1	-0.8
Number of self-reported non-cancer illnesses	1.2	2.1	9.5	-1.6	-2.6	-3.1	-0.7	0.2	0.8	0.4	0.5	0.2	0.4
Age started oral contraceptive pill	1.2	1.5	7.8	-0.1	-2.8	-2.2	-1.0	0.6	1.0	0.2	0.2	-0.0	0.1
Hypothyroidism (self reported)	1.1	2.6	4.7	-0.2	-1.8	-1.6	0.0	-1.4	-2.0	-2.2	-1.5	-2.1	-1.8
Ever had hysterectomy (womb removed)	1.1	1.3	7.1	0.8	-1.0	-1.3	0.5	0.6	2.7	0.7	0.7	0.4	0.9
Fed-up feelings	1.1	1.9	7.5	0.8	1.5	1.3	2.7	1.6	0.2	1.4	1.2	0.1	1.0
Past tobacco smoking	1.1	2.0	7.9	1.7	2.5	2.8	0.5	0.0	-1.0	-0.1	-0.9	-0.3	-1.0
Had menopause	1.1	1.4	3.7	-0.9	-1.4	-1.7	-0.7	0.6	1.9	-0.1	1.1	1.2	1.1
Worrier / anxious feelings	1.1	2.0	5.4	0.5	0.2	-0.2	-0.5	-2.3	0.1	-1.5	-2.3	-1.6	-2.0
Happiness	1.1	1.4	4.9	2.2	1.2	1.4	1.7	0.9	-0.5	1.0	0.4	0.0	0.1
Had major operations	1.1	1.3	4.5	-2.1	0.9	0.7	0.9	0.2	-1.6	-1.2	-0.8	-0.8	-0.9
Long-standing illness, disability or infirmity	1.1	1.7	4.8	-0.6	-2.2	-2.2	-0.9	-0.8	0.6	-1.4	-1.1	-1.1	-1.0
Medication: Blood pressure	1.1	2.0	5.0	-0.3	-2.2	-2.2	-1.3	1.0	1.1	1.5	1.1	1.3	1.2
Neuroticism (Nagel 2018)	1.0	2.3	4.9	-0.9	-0.8	-0.9	-0.8	-1.5	-0.8	-1.9	-2.2	-1.9	-2.1
Schizophrenia (2018)	1.0	2.1	5.1	1.2	2.2	1.9	2.2	1.1	1.0	1.1	0.2	1.3	0.4
Blood Platelet Count	1.0	11.4	29.8	2.6	-0.4	-0.3	3.6	5.5	1.8	4.4	4.4	2.3	4.1
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	3.5	-0.7	-0.3	0.1	-0.0	1.9	0.8	1.9	1.3	0.8	1.1
Medication: Simvastatin	1.0	1.5	5.0	-1.4	-1.9	-2.2	-1.3	-0.7	1.1	-0.6	0.4	0.1	0.5
Father’s age at death	1.0	1.3	3.2	-0.0	0.4	0.4	-1.2	-1.1	-0.9	-1.1	-1.8	-1.2	-1.8
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.6	-1.6	-0.9	-0.8	-0.4	0.9	0.2	0.8	1.3	1.3	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.3	3.1	1.4	0.3	0.5	0.5	-1.3	-1.1	-0.4	-1.8	-1.2	-1.6
Number of children fathered	1.0	1.1	2.5	-1.6	-1.1	-1.2	-0.4	1.0	0.0	0.8	1.6	0.3	1.2
Age at first live birth	1.0	1.8	5.5	0.6	1.5	1.6	2.4	1.4	-0.6	1.9	1.0	0.1	0.8
Illnesses of siblings: Diabetes	1.0	1.2	3.0	-1.1	-1.7	-1.6	-1.6	-0.7	0.6	-0.2	-0.4	1.4	-0.1
Eye problems/disorders: Glaucoma	1.0	1.2	2.8	0.2	-0.1	-0.8	0.4	1.1	0.8	1.5	1.4	1.7	1.5
Ever smoked	1.0	1.7	6.0	-1.5	-2.4	-2.5	-1.6	-0.4	0.5	-0.4	0.4	0.3	0.4
HbA1C	0.9	1.0	2.6	-1.6	-1.6	-1.6	-0.3	0.8	0.7	0.4	0.1	0.9	0.2
Blood Eosinophil Count	0.9	7.1	20.6	-1.8	-2.3	-2.2	-1.6	1.6	4.1	1.1	2.4	4.5	2.8
Cardiovascular Disease	0.9	2.9	12.3	-1.0	-3.4	-3.5	-1.0	-1.1	1.6	0.1	-0.3	0.2	-0.1
Hand grip strength (right)	0.9	2.5	6.4	1.4	1.0	1.0	2.1	1.3	-1.4	2.5	2.0	0.5	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.1	2.1	1.2	0.6	0.9	0.7	-0.9	-0.4	-1.3	-1.4	-1.2	-1.5
Diabetes (self-reported)	0.9	1.4	3.6	-1.9	0.2	-0.3	0.5	0.4	1.7	0.7	1.1	1.9	1.2
Time employed in main current job	0.9	1.1	3.0	0.3	0.7	0.6	0.6	1.5	1.0	1.7	1.1	0.9	1.1
Illnesses of mother	0.9	1.1	5.6	2.4	1.2	1.7	0.7	0.2	-0.3	0.2	-0.0	-0.3	-0.0
Pulse wave Arterial Stiffness index	0.9	1.1	2.5	1.4	-0.1	0.1	-0.2	1.1	0.4	1.4	1.3	1.6	1.2
Glaucoma (self-reported)	0.9	1.1	3.0	-0.2	-1.2	-1.7	-0.4	1.1	0.8	0.6	1.0	1.3	1.0
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	4.2	1.0	-1.2	-0.9	0.3	-1.0	-1.6	-1.4	-1.3	-2.0	-1.6
Birth weight	0.9	2.0	6.9	-1.0	0.6	0.8	-0.3	-0.7	-2.1	-1.4	-1.2	-2.6	-1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	2.4	0.1	1.1	1.4	0.8	1.6	0.6	1.0	0.9	0.7	1.0
Eye problems/disorders: None of the above	0.9	1.0	2.9	0.9	0.9	1.3	0.2	-1.0	-1.7	-0.3	-0.8	-1.4	-0.8
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.8	0.4	0.4	0.9	-1.5	-1.7	-0.7	-1.3	-1.5	-0.1	-1.2
Medication: Bendroflumethiazide	0.9	1.4	3.4	0.7	-1.5	-1.0	-0.8	0.7	1.7	1.4	0.6	1.9	0.8
Vascular/heart problems diagnosed by doctor	0.9	2.5	7.5	0.6	2.7	2.7	1.5	-0.4	-1.3	-1.2	-1.1	-1.3	-1.1
Lupus	0.8	1.3	3.8	1.3	1.9	1.9	0.8	-0.6	-0.9	-0.6	-0.6	-0.8	-0.5
Primary Biliary Cirrhosis	0.8	1.2	3.4	-0.3	0.9	0.5	0.5	1.1	0.8	1.8	1.0	1.9	1.0
Type 2 Diabetes (T2D) (2018)	0.8	1.4	4.4	-2.1	-1.1	-1.5	-0.3	0.0	1.4	0.1	0.9	1.7	0.9
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	2.7	-0.8	-0.6	-0.5	-0.5	-0.9	-0.7	-0.9	-1.3	-1.7	-1.5
Medication for hormone replacement therapy	0.8	0.9	3.7	0.3	1.9	1.6	0.4	-1.2	-0.1	-0.5	-0.6	-0.2	-0.6
Medication: Co-codamol	0.8	0.9	4.6	0.4	1.2	1.1	2.1	0.6	-0.7	-0.2	-0.2	-0.5	-0.3
Serious illness, injury or assault to yourself	0.8	1.0	3.7	-1.5	-1.0	-1.0	-0.0	0.0	-0.3	-0.7	-0.5	-1.9	-1.0
Stomach or abdominal pain in last month	0.8	1.0	2.9	-0.2	0.3	0.5	1.3	0.9	-0.8	0.9	1.7	0.1	1.7
Number of incorrect matches in round	0.8	1.3	4.5	1.2	-0.8	-0.4	-2.1	-0.5	-1.1	-1.4	-0.9	-0.9	-1.0
Pain all over the body in last month	0.8	0.9	3.1	-1.8	-0.4	-1.2	-0.8	-0.6	0.7	-0.7	-1.1	0.4	-1.0
Loud music exposure frequency	0.8	0.8	2.0	-0.4	1.4	1.0	0.8	0.4	-0.5	0.7	1.1	0.9	1.2
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	3.7	-0.6	-1.9	-1.6	-0.2	0.4	1.4	0.6	0.4	0.8	0.6
Exposure to tobacco smoke outside home	0.8	1.1	2.5	-0.7	0.7	0.3	-0.5	-0.7	-1.5	-1.2	-1.4	-1.1	-1.6
Number of full brothers	0.8	0.9	2.0	-0.2	-1.4	-1.1	-1.1	-1.2	-1.0	-0.2	-1.0	-0.7	-1.0
Pulse wave peak to peak time	0.8	0.9	2.4	-1.6	0.2	0.1	0.2	-0.9	-0.6	-1.2	-1.1	-1.4	-0.9
Hypertension (Self-reported)	0.8	2.3	7.2	-0.4	-2.7	-2.5	-1.4	0.4	1.2	1.4	1.1	1.2	1.0
Diabetes diagnosed by doctor	0.8	1.3	4.5	-2.1	-0.2	-0.6	0.8	0.5	1.4	0.6	1.0	1.6	1.0
Mineral and other dietary supplements	0.8	1.0	3.7	0.3	-0.1	-0.4	1.9	1.7	-0.0	1.1	1.2	0.0	0.9
Osteoporosis (self-reported)	0.8	1.0	3.5	-0.5	-1.0	-0.7	1.9	1.3	0.7	-0.3	0.8	0.8	1.0
Medication: Gliclazide	0.8	0.9	3.8	-1.9	-1.1	-1.1	0.4	-0.1	-0.3	-1.3	-0.2	-0.6	-0.1
Diastolic blood pressure, automated reading	0.8	2.5	8.8	1.2	-0.7	-0.9	-2.8	-3.0	-0.3	-1.5	-1.2	0.1	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	4.1	-0.2	-1.3	-1.4	-2.0	-1.0	0.3	-0.8	-0.6	-0.2	-0.6
Bipolar Disorder or Schizophrenia	0.7	1.7	5.5	1.7	1.5	1.2	2.4	1.3	1.5	0.6	0.4	0.9	0.4
Verbal and Numeric Reasoning (VNR)	0.7	1.7	5.1	-0.4	-1.0	-0.8	0.8	1.4	1.6	2.3	1.2	1.4	1.3
Bipolar Disorder (2011)	0.7	0.7	2.5	-0.2	-1.6	-1.6	0.6	0.2	1.0	-0.4	0.4	-0.4	0.6
Waist Hip Ratio (WHR)	0.7	3.1	10.2	-1.4	-3.1	-3.2	-0.7	-1.0	2.6	-0.9	-0.3	0.0	-0.0
Sensitivity / hurt feelings	0.7	1.3	3.1	-0.6	-1.6	-1.8	-0.5	-0.6	1.5	-1.5	-1.1	0.0	-0.6
Supplements: Zinc	0.7	0.7	2.0	0.6	1.1	1.1	0.7	-0.3	1.3	0.1	-0.1	1.4	0.2
Diabetes (mother)	0.7	0.9	1.6	-1.0	-1.1	-0.8	-0.3	0.6	0.5	1.1	1.3	1.3	1.2
Average weekly fortified wine intake	0.7	0.8	1.8	-0.7	0.3	0.2	-1.4	-1.3	-0.7	-1.3	-0.8	-0.6	-0.6
Maternal smoking around birth	0.7	1.0	3.8	1.3	2.0	1.8	0.9	0.7	-0.4	0.1	0.0	-0.4	0.0
High blood pressure	0.7	1.9	5.4	-0.4	-2.3	-2.2	-1.4	0.4	1.1	1.2	1.1	1.2	1.0
Illnesses of siblings	0.7	0.9	4.3	-0.5	1.2	1.0	2.1	0.7	-0.8	0.0	-0.2	-1.1	-0.4
Number of live births	0.7	1.0	2.3	-0.2	-1.2	-1.5	-1.2	-1.0	-0.1	-1.4	-0.6	-0.9	-0.4
Asthma	0.7	1.3	6.3	-0.7	-0.6	-1.2	0.6	0.1	2.5	0.5	0.8	1.6	1.0
Impedance of arm (left)	0.7	3.1	7.7	-0.5	2.4	2.8	1.2	2.1	0.4	1.4	1.6	1.9	1.7
Medication: Paracetamol	0.7	1.1	4.9	-0.3	-2.2	-2.1	-1.0	-0.1	0.1	0.1	0.1	-0.7	0.3
Gout (self-reported)	0.7	0.9	2.3	-1.1	0.1	0.3	0.0	-1.1	-1.4	-1.0	-0.8	-1.5	-1.0
Mouth/teeth dental problems: Loose teeth	0.7	0.9	3.4	-1.8	0.0	-0.0	1.7	0.7	0.4	0.0	0.9	0.0	0.9
Migraine (self-reported)	0.7	0.8	2.1	0.7	-0.8	-0.7	-1.2	0.6	1.1	1.2	0.2	1.5	0.4
Number of full sisters	0.7	0.9	2.8	0.7	0.8	0.7	0.2	-1.7	-0.7	-0.8	-1.2	-0.4	-1.2
Leg pain on walking	0.7	0.8	3.5	-0.9	-1.9	-1.7	-0.9	-0.2	0.0	-0.4	-0.0	-0.4	-0.1
Mood swings	0.7	1.3	8.3	0.9	1.4	1.2	2.9	0.5	0.7	0.4	-0.4	-0.3	-0.1
Medication for cholesterol	0.7	1.1	3.7	0.2	1.2	1.6	1.0	0.3	-1.9	-0.7	-0.2	-1.3	-0.5
Asthma (self-reported)	0.7	1.3	6.3	-0.5	-0.6	-1.3	0.4	0.1	2.5	0.4	0.7	1.6	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	4.3	-0.5	-1.6	-1.5	2.1	1.3	0.5	1.1	1.1	-0.3	0.9
Medication: Paracetamol	0.7	1.0	3.6	-0.3	-1.9	-1.6	-1.6	-0.4	-0.2	-0.4	-0.1	-0.8	0.0
Medication: Lisinopril	0.7	0.9	3.3	1.4	-1.8	-1.3	-0.9	-0.2	0.7	0.4	-0.4	0.5	-0.2
Number of operations (self-reported)	0.7	1.1	3.7	-1.9	-1.4	-1.7	1.0	0.7	0.2	0.0	0.6	0.1	0.6
Fractured/broken bones in last 5 years	0.7	0.9	3.4	-0.5	-0.2	-0.2	1.4	1.9	0.2	0.9	1.3	-0.3	1.1
Heart disease (siblings)	0.7	0.9	3.1	0.8	-1.1	-0.7	-0.5	0.3	1.8	0.5	0.4	1.6	0.7
Impedance of whole body	0.7	3.7	6.1	-0.7	1.9	2.2	1.5	2.4	1.1	1.5	2.3	2.5	2.4
Fasting Glucose	0.6	0.7	1.4	-1.1	-0.5	-0.8	0.3	-0.9	-1.0	-0.8	-0.5	-1.2	-0.5
Neuroticism	0.6	1.6	3.3	-1.2	-1.6	-1.8	-1.1	-0.9	0.6	-1.1	-1.5	-0.9	-1.3
Hearing difficulty/problems: Yes	0.6	0.9	1.9	0.2	-1.4	-1.1	0.0	0.8	1.0	-0.0	1.2	1.2	1.3
Impedance of leg (right)	0.6	2.8	4.6	-0.9	1.2	1.2	2.1	2.0	1.4	1.0	2.0	2.0	2.1
Impedance of leg (left)	0.6	2.9	6.4	-1.0	0.8	0.9	1.5	2.0	1.5	0.9	2.4	2.3	2.5
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	1.6	0.1	-1.3	-1.2	-0.8	-0.9	0.5	-1.2	-1.1	-1.3	-1.0
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	2.3	-0.3	-1.4	-1.5	1.2	-0.8	0.1	-0.3	-0.3	-0.6	-0.6
Breastfed as a baby	0.6	0.8	2.3	1.0	0.6	0.9	-0.4	-0.9	0.8	-0.6	-1.5	0.0	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	2.2	0.5	-0.5	-0.8	0.1	-1.5	-0.5	-0.7	-1.5	-1.3	-1.3
Blood clot in the leg (DVT)	0.6	0.7	4.1	0.0	-0.9	-1.1	-2.0	-0.6	0.3	-0.6	-0.4	-0.1	-0.4
Neck or shoulder pain in last month	0.6	0.8	3.5	0.4	0.8	0.3	0.9	-0.6	-0.9	-1.2	-0.2	-1.9	-0.5
Alcohol intake frequency.	0.6	1.3	4.1	-0.1	-1.0	-1.6	-2.0	-1.0	0.6	-1.2	-1.2	0.4	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.2	-0.5	-0.1	-0.2	0.1	1.0	1.5	0.7	1.2	0.0	1.3
Back pain experienced in last month	0.6	0.9	3.0	-0.6	-0.3	-0.4	-0.6	0.4	0.9	0.2	1.5	1.2	1.7
Illnesses of father: None of the above (group 1)	0.6	0.7	2.9	-0.4	1.7	1.1	1.2	0.5	-0.4	0.5	0.5	-0.4	0.3
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.9	0.4	-0.7	-0.2	-0.3	0.6	-1.6	0.1	0.4	-1.7	-0.1
Supplements: Calcium	0.6	0.7	1.8	-0.3	1.3	1.3	0.7	-1.2	-0.0	-1.2	-0.4	0.4	-0.2
Depression (Nagel 2018)	0.5	0.7	2.8	-0.4	-0.2	-0.1	0.3	-0.8	-0.1	-1.7	-1.1	-1.0	-1.0
Alzheimer’s Disease (in mother)	0.5	0.6	1.4	-1.0	-0.5	0.2	0.8	1.2	-1.0	0.6	0.9	-0.0	0.6
Alzheimer’s Disease (including proxy)	0.5	0.7	3.0	-0.1	0.2	0.7	1.7	0.9	-1.1	0.7	0.8	0.1	0.5
Coronary Artery Disease (CAD)	0.5	0.6	1.9	0.0	-1.2	-0.9	-1.0	-0.1	0.2	1.4	0.6	0.2	0.5
Crohns Disease (2012)	0.5	0.9	3.1	-1.1	1.8	1.6	0.8	-0.4	-0.6	-0.7	-0.3	-0.1	-0.3
LDL Cholesterol	0.5	0.7	2.7	0.5	-0.7	-0.8	-1.0	-0.5	-1.3	-0.4	0.2	-1.6	0.1
Blood White Count	0.5	3.7	8.0	2.8	-1.2	-1.0	1.0	1.8	2.4	2.8	1.6	1.7	1.7
Chronotype (morning person)	0.5	1.2	3.6	1.9	1.4	1.6	1.1	-0.7	-0.6	0.2	-0.7	-0.8	-0.9
Hand grip strength (left)	0.5	1.4	3.3	1.2	1.7	1.4	1.8	-0.2	-1.3	1.2	0.8	-0.5	0.4
Average weekly spirits intake	0.5	0.6	2.4	-0.4	-1.0	-1.6	-0.7	0.1	1.3	-0.1	0.3	0.2	0.4
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.5	-0.1	-1.2	-0.7	-0.6	-0.3	0.7	-1.1	-0.6	-0.4	-0.6
Trunk fat percentage	0.5	1.9	7.0	-1.0	-0.5	-0.6	0.4	2.6	0.3	0.8	1.9	1.4	1.9
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	2.2	-0.3	1.0	1.1	1.5	0.2	-0.5	-0.6	-0.2	-0.7	-0.1
Supplements: Glucosamine	0.5	0.7	3.0	0.1	0.4	0.3	-1.7	-0.5	-0.8	-0.4	-0.8	-0.9	-0.8
Medication: Levothyroxine sodium	0.5	0.8	1.6	0.2	-1.3	-1.1	-0.8	-0.7	-1.1	-1.1	-0.4	-1.0	-0.6
Nervous feelings	0.5	1.0	2.2	0.2	-1.2	-1.5	-1.5	-1.1	0.2	-0.3	-0.8	-1.0	-0.8
Forced vital capacity (FVC)	0.5	1.9	4.9	0.7	0.5	0.9	2.2	1.3	-1.5	2.2	1.6	-0.3	1.2
Allergy	0.5	1.0	3.5	0.7	1.7	1.9	-0.5	0.7	-1.3	0.6	0.7	0.2	0.6
Alcohol intake versus 10 years previously	0.5	0.7	1.4	0.9	1.0	0.6	0.2	1.1	0.6	0.6	1.0	1.2	1.0
Falls in the last year	0.5	0.7	3.5	0.1	-1.1	-1.1	-0.1	-0.2	1.9	-0.5	-0.6	0.8	-0.3
Hair/balding pattern: Pattern 3	0.5	0.7	2.0	0.1	-1.3	-1.4	-1.3	-0.1	1.0	-0.7	-0.2	-0.0	-0.2
Lung cancer (father)	0.5	0.6	1.5	-1.2	-1.1	-1.2	-0.6	0.2	0.9	-0.4	0.3	0.3	0.5
Peak expiratory flow (PEF)	0.5	1.2	5.7	-0.4	-0.6	-0.3	1.2	0.6	-0.3	2.4	1.4	-0.4	1.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	3.1	-0.1	0.7	0.3	0.6	0.3	0.2	0.5	0.8	1.8	0.8
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.7	-0.5	1.6	1.5	0.8	-0.4	-1.1	-0.4	-0.2	-1.0	-0.3
Comparative body size at age 10	0.5	1.4	2.3	-0.2	-1.5	-1.5	-0.3	-0.8	-0.8	-1.5	-1.3	-1.5	-1.3
Medication for pain relief, constipation, heartburn	0.5	0.9	1.6	-0.4	1.2	1.2	-0.5	-1.2	-0.8	-1.0	-1.0	-0.8	-1.0
Medication: Omeprazole	0.5	0.6	1.7	-0.6	-0.4	-0.2	0.8	-0.5	-1.2	-0.9	-0.2	-1.3	-0.3
Chest pain or discomfort	0.5	0.8	2.8	-0.3	0.2	-0.0	0.1	-1.2	0.2	-0.9	-1.7	-0.6	-1.4
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	4.0	2.0	0.2	0.4	-0.9	-0.0	0.1	-0.1	-0.6	0.3	-0.5
Friendships satisfaction	0.5	0.6	3.0	1.2	-0.1	0.1	1.7	0.3	0.8	0.3	-0.6	0.1	-0.7
Guilty feelings	0.5	0.7	3.4	-1.8	-0.6	-1.2	0.1	0.9	0.3	0.6	0.5	-0.7	0.5
Wears glasses or contact lenses	0.5	0.6	2.2	-1.1	-1.5	-1.3	0.5	0.3	0.1	-0.6	-0.2	-0.7	-0.2
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.6	0.3	0.1	-0.0	1.0	1.6	0.9	1.1	0.4	0.2	0.5
Pain type(s) experienced in last month: Hip pain	0.5	0.6	4.0	2.0	0.3	0.7	0.6	0.3	0.7	0.5	-0.2	0.2	-0.1
Irritability	0.5	0.9	2.6	0.3	1.3	1.4	0.8	1.0	-1.6	0.7	0.5	-0.1	0.0
Cholesterol lowering medication	0.5	0.7	2.5	-0.2	-1.4	-1.6	-0.6	-0.1	1.5	-0.0	-0.2	0.5	-0.1
Schizophrenia vs Biploar Disorder	0.4	0.5	1.6	0.8	0.9	1.0	0.5	0.4	0.8	0.4	-0.0	1.3	0.2
Alzheimer’s Disease (in father)	0.4	0.4	2.8	0.3	0.3	0.5	1.7	0.2	-1.0	0.2	0.1	-0.1	0.0
Breast Cancer	0.4	1.0	3.1	0.3	1.4	1.8	-0.8	-0.6	-1.8	-0.8	-0.5	-0.3	-0.6
HDL Cholesterol	0.4	0.6	1.3	0.5	0.7	0.9	1.1	-0.5	-1.1	0.5	0.6	-1.0	0.4
Rheumatoid Arthritis	0.4	0.5	1.2	-0.4	-0.9	-0.6	0.0	1.1	0.8	0.6	0.9	0.6	0.7
Lung FVC	0.4	1.8	3.4	-0.5	-1.5	-1.3	1.8	1.4	-0.7	1.1	1.7	-1.6	1.2
Angina	0.4	0.6	1.9	0.0	-1.4	-1.1	1.2	-0.2	0.1	-0.3	-0.4	-0.6	-0.5
Age when periods started (menarche)	0.4	0.9	3.6	1.4	0.7	0.9	0.5	-0.4	-1.1	-0.3	-0.4	-1.9	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	3.3	-0.3	0.5	0.2	0.5	-1.8	-1.0	-0.7	-1.3	-0.6	-1.3
Qualifications: CSEs or equivalent	0.4	0.5	1.6	0.3	0.7	0.7	0.7	-0.0	-0.2	0.6	1.2	0.3	1.3
Waist circumference	0.4	1.5	6.6	-1.1	-2.4	-2.6	-0.5	0.6	0.4	-0.1	0.5	-0.1	0.5
Fluid intelligence score	0.4	0.9	4.4	0.8	-0.1	0.2	0.6	0.6	1.3	2.1	0.4	1.2	0.5
Impedance of arm (right)	0.4	2.0	6.0	-0.5	2.1	2.4	0.8	1.6	0.5	0.6	1.1	1.5	1.2
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	4.8	0.7	0.1	0.5	1.4	0.4	-2.2	1.6	0.7	-1.2	0.3
Qualifications: A levels/AS levels or equivalent	0.4	1.0	2.7	0.2	1.3	1.4	0.6	1.0	-0.6	1.6	1.0	0.2	0.8
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.0	-0.4	-0.1	-0.5	0.0	-0.0	-0.7	-1.0	-0.9	-0.9	-0.9
High blood pressure (siblings)	0.4	0.5	2.3	-0.1	-1.1	-0.9	-1.5	-0.7	-0.2	0.1	0.4	-0.3	0.4
Body fat percentage	0.4	1.4	4.9	-0.7	-0.9	-1.1	0.3	2.2	0.4	0.4	1.6	1.1	1.6
Leg fat percentage (right)	0.4	1.3	3.3	-0.5	-1.4	-1.8	0.6	1.8	0.8	0.1	1.2	0.7	1.2
Emphysema/chronic bronchitis	0.4	0.5	1.0	0.9	-0.3	-0.3	-0.1	-0.5	0.9	-1.0	-0.9	-0.3	-0.8
Angina (self-reported)	0.4	0.5	1.9	0.1	-1.4	-1.1	1.1	-0.3	0.1	-0.3	-0.3	-0.6	-0.4
Suffer from ‘nerves’	0.4	0.7	4.2	-0.1	-0.4	-0.6	0.1	0.5	1.2	2.0	0.6	0.1	0.5
Family relationship satisfaction	0.4	0.5	2.1	1.4	0.5	0.8	0.0	0.7	0.1	1.1	0.4	0.4	0.1
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.3	-0.7	1.1	1.1	0.5	-0.4	-0.7	-0.8	0.1	-0.3	0.1
Ever had bowel cancer screening	0.4	0.4	0.8	0.7	-0.3	-0.1	-0.9	-0.6	-0.5	-0.7	-0.7	-0.8	-0.8
Qualifications: nursing, teaching	0.4	0.6	1.5	-0.8	-1.2	-0.9	-1.2	-0.7	-0.3	-0.4	-0.7	0.4	-0.7
Commuting to job workplace: Walk	0.4	0.5	1.6	0.4	-0.2	-0.5	-0.7	-0.6	-0.1	-0.5	-1.2	-0.4	-1.2
Breast cancer (self-reported)	0.4	0.5	1.6	0.0	-0.5	-0.1	-0.3	0.7	0.5	0.9	1.3	0.2	1.1
Leg fat percentage (left)	0.4	1.5	3.5	-0.4	-1.5	-1.8	0.3	1.9	1.0	0.2	1.4	1.0	1.4
Commuting to job workplace: Cycle	0.4	0.5	2.3	-0.1	0.6	0.4	0.6	0.4	1.2	1.5	-0.1	0.6	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.2	-1.0	-0.5	-0.5	0.9	-0.3	-0.7	-1.1	-0.2	-1.0	-0.3
Basal cell carcinoma (self-reported)	0.4	0.5	2.5	-0.3	-1.1	-1.0	0.3	-0.1	1.6	0.3	0.1	0.3	0.2
Bipolar Disorder (2018)	0.3	0.5	1.4	1.2	-0.4	-0.5	1.0	0.6	1.1	-0.3	0.3	-0.2	0.2
Intelligence (Savage-Jansen 2018)	0.3	0.8	3.1	-0.0	-1.8	-1.6	0.3	-0.5	0.6	1.0	-0.2	-0.6	-0.2
Ovarian Cancer	0.3	0.5	1.5	-1.2	-0.4	-0.7	-0.3	-1.0	0.9	-0.5	-0.1	0.6	-0.1
BMI	0.3	1.5	6.5	-0.3	-2.5	-2.5	-0.6	0.2	0.0	-0.6	-0.4	-0.7	-0.5
Lung FEV1/FVC ratio	0.3	1.5	6.2	0.2	-2.5	-2.1	-1.4	0.7	-0.6	0.9	0.2	-0.7	-0.2
Relative age of first facial hair	0.3	0.6	1.4	0.6	1.2	1.2	0.3	0.1	0.3	1.0	0.5	1.0	0.7
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.2	0.0	-0.4	-0.7	-0.5	-0.4	1.1	-0.9	-0.8	-0.2	-0.7
Systolic blood pressure, automated reading	0.3	0.9	3.9	0.8	-1.6	-2.0	-0.3	-0.1	0.8	0.1	0.4	0.9	0.4
Vitamin and mineral supplements	0.3	0.4	1.8	0.2	0.0	-0.1	0.8	0.7	-0.9	-0.0	-0.2	-1.4	-0.2
Townsend deprivation index at recruitment	0.3	0.4	1.5	0.2	-0.5	-1.2	1.0	0.6	0.5	0.2	0.4	-0.6	0.3
High blood pressure (mother)	0.3	0.5	2.3	-1.5	0.4	-0.0	0.0	-0.8	-0.2	-0.5	-0.7	-0.2	-0.7
Trunk fat mass	0.3	1.3	4.0	-1.3	-0.9	-1.0	-0.1	2.0	-0.2	0.6	1.5	0.9	1.4
Had other major operations	0.3	0.4	2.7	-0.0	-0.1	-0.2	1.7	0.5	-0.5	-0.1	0.3	-0.4	0.1
Medication: Ramipril	0.3	0.4	1.4	-0.3	0.2	-0.1	-0.3	0.1	0.7	0.7	0.9	1.2	0.8
Trunk fat-free mass	0.3	1.5	3.4	-1.4	-1.1	-1.2	-1.2	-1.3	-1.8	-0.4	-0.8	-1.4	-1.1
Hip circumference	0.3	1.4	3.7	-0.8	-1.9	-1.8	-0.4	1.5	-0.2	1.1	1.1	0.6	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.6	2.1	-1.1	-1.1	-0.8	0.1	0.0	1.5	-0.3	-0.4	0.5	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	4.7	-0.3	0.0	0.3	0.8	0.8	-2.2	1.4	1.0	-1.0	0.6
Trunk predicted mass	0.3	1.6	3.3	-1.5	-1.1	-1.2	-1.2	-1.3	-1.8	-0.4	-0.8	-1.4	-1.1
Forced vital capacity (FVC), Best measure	0.3	1.2	3.3	-0.7	0.1	0.4	1.3	1.1	-1.8	1.4	1.5	-0.4	1.1
Wheeze or whistling in the chest in last year	0.3	0.6	1.5	-0.2	-0.4	-1.0	0.4	-0.6	1.2	-0.8	-1.0	0.4	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.9	-1.0	-0.6	-0.4	-0.0	-0.6	-0.6	-0.9	0.2	-0.3	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.7	-1.3	0.0	0.1	-0.6	0.3	0.1	0.2	0.6	0.6	0.7
Illnesses of father: Heart disease	0.3	0.5	1.1	0.1	-0.7	-1.1	0.3	-0.8	0.3	-0.9	-0.8	-0.5	-0.8
Smoking status: Previous	0.3	0.5	1.9	-0.8	-1.1	-1.4	0.0	-0.7	-0.1	0.1	0.2	-0.4	0.3
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.1	-0.2	-0.7	-1.0	-0.2	-0.2	1.0	-0.7	-0.1	0.3	0.1
Osteoarthritis (self-reported)	0.3	0.4	1.4	-0.9	-0.5	-0.9	-1.2	0.4	-0.2	0.2	0.1	-0.4	0.1
Miserableness	0.3	0.6	3.2	-0.6	0.2	-0.2	1.8	-0.5	-0.1	-1.0	-0.4	-0.8	-0.4
Average weekly beer plus cider intake	0.3	0.4	1.3	-0.5	0.6	0.5	1.2	-0.1	-0.9	-0.6	0.1	-1.0	0.0
Ever depressed for a whole week	0.3	0.3	1.7	-1.3	0.3	0.2	0.5	-0.1	-1.0	0.1	-0.1	-0.2	-0.2
Pain experienced in last month	0.3	0.5	1.0	-0.3	-0.8	-0.3	-0.8	-0.1	-1.0	-0.1	-0.7	-0.7	-1.0
Pack years of smoking	0.3	0.5	2.0	0.4	0.6	0.6	1.4	0.8	0.6	0.8	0.1	0.3	0.1
Depressed Affect (Nagel 2018)	0.2	0.5	1.2	-0.2	-0.5	-0.6	1.1	-0.1	0.5	-0.9	-0.9	-0.6	-0.7
Age at First Birth	0.2	0.3	0.9	-0.2	-0.8	-0.6	-0.3	-0.6	0.0	-0.3	-1.0	-0.1	-0.8
Height	0.2	4.4	14.0	-3.7	1.3	2.1	-2.3	0.8	-3.7	0.6	1.4	0.8	0.9
Systolic Blood Pressure	0.2	1.2	4.4	1.4	-0.4	-0.8	-0.1	-2.1	-0.3	-1.0	-1.3	-0.3	-1.3
Diabetes (father)	0.2	0.3	0.7	-0.8	0.8	0.8	-0.6	-0.2	-0.4	-0.8	-0.2	-0.2	-0.1
Pack years adult smoking proportion	0.2	0.3	1.3	0.4	0.5	0.6	1.1	0.4	0.2	0.6	-0.1	0.1	-0.0
Relative age voice broke	0.2	0.3	1.0	-1.0	0.7	0.4	0.2	-0.8	0.2	0.2	-0.5	-0.1	-0.2
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	1.2	-0.1	0.3	-0.0	-0.2	0.1	1.1	0.8	-0.0	-0.1	0.0
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.0	-0.5	-1.0	-0.9	0.6	-0.7	0.6	-0.3	-0.7	-0.0	-0.7
Multivitamins +/- minerals	0.2	0.3	0.8	0.6	0.7	0.8	-0.2	-0.9	0.4	-0.2	-0.1	0.7	-0.2
Sitting height	0.2	1.4	5.0	-0.2	0.8	1.9	-0.3	0.7	-2.2	1.7	0.8	0.4	0.3
Body mass index (BMI)	0.2	0.8	4.6	-0.1	-1.8	-2.1	-0.2	0.4	-0.0	-0.3	0.1	-0.3	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.8	-0.3	0.2	-0.1	0.3	-1.3	-0.6	-0.5	-1.0	-0.2	-1.0
Qualifications: None of the above	0.2	0.4	1.0	0.2	-0.3	-0.7	0.9	0.6	1.0	0.5	0.5	0.1	0.5
Neuroticism score	0.2	0.4	0.9	-1.0	-0.3	-0.8	0.3	-0.5	0.2	-0.1	-0.7	-1.0	-0.7
Arm fat percentage (right)	0.2	0.7	2.7	-0.6	-1.4	-1.6	-0.4	0.9	-0.1	-0.6	0.3	0.1	0.3
Arm fat mass (right)	0.2	0.9	3.5	-0.9	-1.7	-1.9	-0.6	1.0	-0.4	0.0	0.6	0.1	0.5
Standing height	0.2	2.0	6.1	-2.5	1.0	1.5	-0.8	1.0	-1.9	1.5	1.4	0.8	1.0
Headache pain in last month	0.2	0.3	1.5	0.4	-0.1	-0.4	0.2	-1.2	-0.2	0.4	-0.5	-0.7	-0.4
Health satisfaction	0.2	0.3	0.7	0.4	-0.4	-0.3	0.3	-0.0	0.3	-0.4	-0.8	-0.9	-0.8
Whole body fat mass	0.2	0.9	2.7	-1.0	-1.0	-1.3	-0.0	1.6	-0.2	0.3	1.2	0.6	1.1
Leg fat mass (right)	0.2	0.8	2.7	-0.6	-1.3	-1.6	0.3	1.4	-0.1	0.3	0.9	0.2	0.8
Comparative height size at age 10	0.2	0.9	4.7	-2.2	0.2	0.7	-1.0	0.7	-0.8	0.5	1.0	0.6	0.7
Age at last live birth	0.2	0.3	0.9	-0.1	0.7	0.9	1.0	0.4	-0.7	0.4	0.3	-0.3	0.4
Supplements: Vitamin C	0.2	0.3	1.4	0.3	0.6	0.5	-1.2	0.1	-0.6	0.1	0.1	0.7	0.1
Knee pain experienced in last month	0.2	0.3	0.9	-0.7	-0.2	-0.2	-0.0	0.9	-0.1	-0.8	0.6	-0.4	0.5
Whole body fat-free mass	0.2	1.1	3.2	-1.1	-1.0	-1.0	-1.1	-1.0	-1.8	-0.1	-0.6	-1.2	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	0.5	0.1	-0.3	-0.5	0.6	0.7	0.3	0.6	0.6	0.4	0.6
Whole body water mass	0.2	1.1	3.5	-1.0	-0.9	-1.0	-1.1	-0.9	-1.9	-0.1	-0.6	-1.3	-0.9
Arm fat mass (left)	0.2	0.6	2.3	-0.7	-1.4	-1.5	-0.4	0.9	-0.6	-0.0	0.4	-0.1	0.3
Basal metabolic rate	0.2	0.9	3.2	-1.0	-1.0	-1.0	-1.0	-0.6	-1.8	-0.1	-0.4	-1.0	-0.7
Arm fat-free mass (left)	0.2	0.9	2.8	-1.1	-1.4	-1.7	-0.9	-0.5	-1.1	0.2	-0.1	-0.8	-0.3
Myopia	0.2	0.4	1.7	0.8	0.6	1.3	0.7	-0.0	-0.5	0.1	0.1	0.2	0.2
Leg fat mass (left)	0.2	0.8	2.2	-0.5	-1.2	-1.5	0.2	1.4	-0.2	0.4	1.1	0.4	1.0
Arm predicted mass (left)	0.2	1.1	3.0	-1.1	-1.6	-1.7	-1.0	-0.5	-1.2	-0.1	-0.2	-0.9	-0.4
Neuroticism (2016)	0.1	0.2	0.3	-0.3	-0.5	-0.4	0.3	-0.1	0.4	0.3	-0.4	-0.5	-0.5
Blood Red Count	0.1	0.9	2.7	-1.6	-1.6	-1.0	-0.8	-0.3	-0.7	-1.2	-0.3	0.5	-0.2
Allergy or Eczema	0.1	0.3	0.7	-0.6	-0.8	-0.8	0.5	-0.7	0.6	-0.4	-0.3	0.0	-0.2
Respiratory disease	0.1	0.3	1.9	-0.1	-0.3	-0.6	-0.4	-0.5	1.4	-0.2	-0.3	0.4	-0.1
Leg fat-free mass (left)	0.1	0.7	3.5	-0.5	-0.3	-0.4	-0.8	-0.6	-1.9	0.2	-0.6	-1.0	-0.8
Leg predicted mass (left)	0.1	0.7	3.8	-0.5	-0.3	-0.3	-0.8	-0.6	-1.9	0.2	-0.6	-1.0	-0.9
Alcohol usually taken with meals	0.1	0.2	1.3	0.4	0.0	-0.1	-1.1	-0.2	0.3	0.1	-0.2	-0.3	-0.3
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.5	-0.3	0.0	0.2	-0.0	-0.7	-0.1	-0.0	-0.7	0.2	-0.7
Financial difficulties in last 2 years	0.1	0.2	0.9	-1.0	0.1	-0.5	0.3	-0.5	-0.2	-0.4	-0.1	-0.5	-0.2
Weight	0.1	0.7	1.8	-1.2	-1.2	-1.4	-0.5	0.8	-0.7	0.4	0.7	0.2	0.6
Length of working week for main job	0.1	0.1	0.4	-0.7	0.2	-0.1	0.1	-0.3	0.1	-0.0	-0.1	-0.0	0.0
Hair/balding pattern: Pattern 4	0.1	0.3	1.6	-0.8	-0.1	-0.0	-1.2	-0.9	-0.3	-0.3	0.2	0.5	0.1
Arm fat-free mass (right)	0.1	0.7	1.8	-0.9	-1.2	-1.3	-0.6	-0.4	-1.3	0.5	0.1	-0.8	-0.2
Qualifications: College or University degree	0.1	0.2	1.0	0.2	0.0	0.5	-0.0	0.7	-0.1	1.0	0.3	0.5	0.1
Medication: Allopurinol	0.1	0.2	0.7	-0.8	0.1	0.1	-0.1	0.1	0.4	0.6	0.2	-0.6	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.5	-0.6	0.5	0.2	0.7	0.0	0.1	-0.2	-0.5	-0.1	-0.4
Arm predicted mass (right)	0.1	0.7	1.9	-0.9	-1.4	-1.4	-0.5	-0.1	-1.2	0.6	0.2	-0.7	-0.1
Leg fat-free mass (right)	0.1	0.8	3.6	-0.4	-0.5	-0.5	-1.1	-0.7	-1.9	0.1	-0.5	-1.0	-0.7
Arm fat percentage (left)	0.1	0.5	1.4	-0.4	-0.9	-1.2	-0.1	1.2	-0.2	-0.1	0.5	0.3	0.5
Loneliness, isolation	0.1	0.1	0.6	0.1	0.2	-0.4	0.2	-0.8	0.2	0.1	-0.5	-0.3	-0.4
Leg predicted mass (right)	0.1	0.8	3.6	-0.4	-0.6	-0.5	-1.2	-0.7	-1.9	0.1	-0.5	-0.9	-0.7
Hearing aid user	0.1	0.1	0.5	0.5	0.3	0.7	0.2	0.5	-0.3	0.2	0.2	-0.0	0.0
Mother’s age at death	0.1	0.1	0.3	0.4	0.4	0.6	-0.1	-0.1	0.3	0.3	-0.4	0.3	-0.5
Commuting to job workplace: Public transport	0.1	0.1	0.7	0.9	-0.5	-0.5	0.2	0.1	-0.3	0.0	-0.0	-0.1	-0.2
Unable to work because of sickness or disability	0.1	0.1	0.6	-0.4	0.5	0.7	-0.3	-0.2	0.0	-0.3	-0.2	-0.1	-0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Heel T-Score	0.0	0.3	0.9	-0.4	0.4	-0.1	0.5	-0.9	-0.3	-0.5	-0.6	-0.6	-0.8
Hair Pigment	0.0	0.6	1.4	0.0	-1.0	-0.8	0.3	0.8	1.2	0.4	0.5	1.2	0.4
Tanning	0.0	0.4	1.3	0.1	0.2	0.3	0.8	-0.2	0.3	-0.3	-0.9	-1.1	-0.7

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