TWAS hub - KRT6A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1240	0.0460	0.0057	0.002	NA	0.011	NA	0.000	2.4e-01	NA	8.7e-02	NA	3.1e-01
2	TCGA	Prostate Adenocarcinoma	0.0842	0.0547	0.0010	0.055	0.03	0.050	NA	0.052	1.9e-06	0.00034	5.6e-06	NA	4.0e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Basal cell carcinoma (self-reported)	16.9	20.0	28.2	5.3	-3.4
Taking other prescription medications	5.5	8.6	9.5	3.1	-2.8
Hair/balding pattern: Pattern 4	5.4	13.0	16.5	-4.1	3.1
Hayfever, allergic rhinitis or eczema	5.2	11.3	19.6	1.7	-4.4
Ever had stillbirth, spontaneous miscarriage or termination	4.7	5.0	5.7	-2.4	2.1
Allergy	4.6	10.5	16.4	-2.1	4.0
Medication: Lansoprazole	4.4	5.0	7.2	-1.7	2.7
Medication: Co-codamol	4.0	4.6	7.5	1.3	-2.7
Long-standing illness, disability or infirmity	3.9	6.0	7.4	2.1	-2.7
Family relationship satisfaction	3.6	4.4	5.5	2.3	-1.8
Alcohol drinker status: Never	3.4	4.1	7.2	2.7	-1.0
Alzheimer’s Disease (in father)	3.3	3.6	4.4	2.1	-1.6
Happiness	3.2	3.8	6.6	1.0	-2.6
Seen a psychiatrist for nerves, anxiety, tension or depression	3.2	4.1	5.2	1.7	-2.3
Worrier / anxious feelings	3.1	5.8	11.6	0.2	-3.4
Alzheimer’s Disease (including proxy)	3.0	4.3	7.7	2.8	-0.9
Suffer from ‘nerves’	3.0	4.7	5.9	1.9	-2.4
Osteoporosis (self-reported)	3.0	3.7	5.0	1.5	-2.2
Allergy or Eczema	2.9	7.7	13.7	1.3	-3.7
Medication: Ventolin 100micrograms inhaler	2.9	3.7	5.5	2.4	-1.4
Ever taken oral contraceptive pill	2.9	3.2	6.2	2.5	-0.4
Health satisfaction	2.8	3.6	5.8	1.2	-2.4
Falls in the last year	2.6	3.5	5.0	2.2	-1.4
Medication: Lisinopril	2.6	3.3	6.2	0.7	-2.5
Glaucoma (self-reported)	2.5	3.0	4.0	1.4	-2.0
Medication: Omeprazole	2.4	2.9	4.9	2.2	-0.9
Severe depression (siblings)	2.3	2.6	3.9	2.0	-1.1
Number of live births	2.3	3.3	6.2	2.5	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	2.2	6.9	10.3	-3.2	1.8
Number of treatments/medications taken	2.1	3.8	4.8	1.7	-2.2
Knee pain experienced in last month	2.1	3.3	4.9	2.2	-1.3
Alzheimer’s Disease (in mother)	2.0	2.3	4.6	2.1	-0.3
Asthma	2.0	3.9	4.3	2.1	-1.9
Mood swings	2.0	3.6	6.7	0.8	-2.6
Type 2 Diabetes (T2D) (2012)	1.9	2.2	3.2	-1.1	1.8
Ever had hysterectomy (womb removed)	1.9	2.1	3.8	-1.9	-0.7
Breastfed as a baby	1.9	2.3	4.6	0.4	2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.9	2.9	4.4	2.1	-1.2
Peak expiratory flow (PEF)	1.9	4.3	6.6	-1.4	2.6
Leg pain on walking	1.9	2.4	4.2	0.8	-2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.9	4.1	5.0	-2.2	1.8
Supplements: Calcium	1.9	2.1	2.8	1.7	1.2
Neuroticism score	1.8	3.7	6.8	0.8	-2.6
Worry too long after embarrassment	1.8	3.0	5.8	0.3	-2.4
Lung FEV1/FVC ratio	1.7	8.4	10.8	-2.5	3.3
Birth weight of first child	1.7	3.2	6.1	-2.5	-0.5
Tinnitus: Yes, now most or all of the time	1.7	2.0	3.2	-1.8	0.9
Forced expiratory volume in 1-second (FEV1)	1.6	5.4	6.0	-2.4	2.2
Handedness (chirality/laterality): Left-handed	1.6	1.9	3.7	-1.9	0.4
Worry (Nagel 2018)	1.5	3.2	5.6	0.9	-2.4
Financial difficulties in last 2 years	1.5	2.1	3.1	-1.8	1.0
Asthma (self-reported)	1.5	3.0	3.2	1.7	-1.8
Smoking status: Current	1.5	2.4	4.7	2.2	-0.5
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	2.9	-0.4	1.7
Hair/balding pattern: Pattern 2	1.4	1.8	3.2	1.8	-0.7
Wheeze or whistling in the chest in last year	1.4	2.5	4.1	1.0	-2.0
Average weekly beer plus cider intake	1.4	2.0	2.3	1.5	1.3
Current tobacco smoking	1.3	2.1	3.8	1.9	-0.6
Schizophrenia vs Biploar Disorder	1.2	1.6	3.0	-1.7	-0.4
Pulse rate	1.2	2.0	3.6	0.6	-1.9
Commuting to job workplace: Car/motor vehicle	1.2	1.4	2.4	-1.5	0.7
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.5	4.7	0.5	-2.2
Alcohol usually taken with meals	1.1	1.7	3.1	-1.8	-0.6
Mouth/teeth dental problems: Bleeding gums	1.1	1.5	2.2	-1.5	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	2.2	0.7	1.5
Illnesses of father: None of the above (group 1)	1.1	1.4	2.6	1.6	-0.4
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	1.5	1.2	-1.0
Maternal smoking around birth	1.0	1.4	2.1	0.9	1.4
Fed-up feelings	1.0	1.8	3.4	1.8	-0.5
Chronic bronchitis/emphysema (father)	1.0	1.1	1.1	-1.1	1.1
Qualifications: None of the above	1.0	2.2	3.6	1.9	-0.9
Comparative body size at age 10	1.0	2.9	3.9	-1.4	2.0
Shortness of breath walking on level ground	1.0	1.2	2.3	0.3	-1.5
Illnesses of father: High blood pressure	1.0	1.3	2.5	-1.6	-0.2
Myopia	1.0	1.5	2.9	-0.2	-1.7
Rheumatoid Arthritis	0.9	1.2	2.3	1.5	0.3
Respiratory disease	0.9	1.9	2.8	1.7	-1.0
Medication for hormone replacement therapy	0.9	1.0	2.0	1.4	0.2
Impedance of leg (left)	0.9	4.5	8.5	0.7	-2.9
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.3	2.1	1.5	-0.8
Illnesses of mother	0.9	1.1	1.7	-1.3	-0.7
Forced vital capacity (FVC), Best measure	0.9	3.2	5.7	-2.4	0.8
Exposure to tobacco smoke outside home	0.9	1.2	1.5	1.2	0.9
Medication: Ibuprofen	0.9	1.1	1.6	1.3	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	1.3	0.9	1.1
Age at last live birth	0.9	1.3	1.6	1.3	1.0
Commuting to job workplace: Walk	0.9	1.0	1.5	-0.7	1.2
Miserableness	0.9	1.6	2.2	1.5	-1.0
Impedance of whole body	0.9	4.7	9.4	0.1	-3.1
Age at First Birth	0.8	1.2	2.4	0.1	-1.5
Neuroticism (2016)	0.8	1.2	2.0	0.6	-1.4
Neuroticism	0.8	1.9	3.5	-0.5	-1.9
Supplements: Zinc	0.8	0.8	1.2	1.1	0.7
Medication: Metformin	0.8	1.1	2.2	1.5	-0.1
Hand grip strength (right)	0.8	2.2	3.6	0.9	1.9
Relative age voice broke	0.8	1.2	2.1	-0.6	1.4
Supplements: Glucosamine	0.8	1.0	1.7	-0.5	1.3
Body mass index (BMI)	0.8	3.3	3.8	1.9	1.7
Nervous feelings	0.8	1.6	2.5	0.8	-1.6
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	1.8	1.4	-0.9
Lung cancer (father)	0.8	1.0	1.0	1.0	1.0
Arm fat mass (right)	0.8	3.2	4.2	2.1	1.4
Supplements: Vitamin C	0.8	1.0	1.5	-0.6	1.2
Illnesses of siblings: Diabetes	0.8	1.0	2.0	1.4	0.1
Ever had bowel cancer screening	0.8	0.9	1.4	-0.6	1.2
Friendships satisfaction	0.8	0.9	1.4	0.7	-1.2
Medication: Aspirin	0.8	1.0	2.0	1.4	-0.1
Arm fat mass (left)	0.8	3.2	4.0	2.0	1.5
Number of self-reported non-cancer illnesses	0.8	1.3	2.2	0.7	-1.5
Average weekly champagne plus white wine intake	0.8	1.1	2.0	-1.4	0.4
Pain type(s) experienced in last month: Hip pain	0.8	1.0	1.3	1.1	-0.9
Leg fat percentage (left)	0.8	2.7	5.5	2.3	-0.0
Heel T-Score	0.7	5.9	10.6	1.1	-3.3
Impedance of leg (right)	0.7	3.5	7.0	0.0	-2.6
Waist circumference	0.7	2.6	4.1	2.0	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	3.3	0.3	-1.8
Pain all over the body in last month	0.7	0.8	1.6	1.2	-0.1
Arm fat percentage (right)	0.7	2.7	4.3	2.1	1.0
Hip circumference	0.7	2.8	4.0	2.0	1.3
Prospective memory result	0.7	0.9	1.3	-0.7	1.1
Headache pain in last month	0.7	1.2	2.3	0.2	-1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.1	-1.1	0.7
Commuting to job workplace: Public transport	0.7	0.8	1.5	-1.2	-0.4
Heart disease (siblings)	0.7	0.9	1.3	-0.7	1.1
Depression (Nagel 2018)	0.6	0.9	1.8	1.4	-0.1
Neuroticism (Nagel 2018)	0.6	1.5	2.9	0.3	-1.7
Bipolar Disorder (2011)	0.6	0.6	0.6	0.7	-0.8
Triglycerides	0.6	0.9	1.6	-0.5	1.3
Tanning	0.6	7.3	9.1	-2.3	3.0
Average weekly spirits intake	0.6	0.8	1.3	1.1	-0.6
Sensitivity / hurt feelings	0.6	1.0	1.7	0.5	-1.3
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	1.1	0.6	-1.0
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.6	0.1	-1.3
Diabetes (father)	0.6	0.7	1.5	-1.2	0.2
Heart attack	0.6	0.7	1.2	1.1	-0.4
Medication: Ramipril	0.6	0.7	1.4	0.1	1.2
Impedance of arm (right)	0.6	2.8	5.6	-0.2	-2.4
Body fat percentage	0.6	2.3	4.4	2.1	0.4
Neck or shoulder pain in last month	0.6	0.9	1.6	-0.4	-1.3
Heart disease (mother)	0.6	0.8	1.1	0.7	1.1
Arm predicted mass (right)	0.6	3.3	6.5	0.4	2.5
Illnesses of father: Heart disease	0.6	0.8	1.7	-0.1	1.3
Arm fat percentage (left)	0.6	2.5	3.5	1.9	1.2
Back pain experienced in last month	0.6	0.8	1.1	0.7	1.1
Financial situation satisfaction	0.6	0.8	1.3	1.1	-0.6
Leg fat mass (left)	0.6	2.3	3.9	2.0	0.8
Reaction Time	0.5	0.9	1.1	-1.1	0.8
BMI	0.5	2.7	5.3	2.3	0.2
Leg fat-free mass (left)	0.5	2.7	5.3	0.1	2.3
Trunk fat percentage	0.5	2.1	4.1	2.0	0.2
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.9	-0.3	1.0
Stomach or abdominal pain in last month	0.5	0.7	1.0	0.5	-1.0
Leg predicted mass (left)	0.5	2.7	5.5	0.1	2.3
Forced vital capacity (FVC)	0.5	2.1	3.7	-1.9	0.7
Mouth/teeth dental problems	0.5	0.8	1.1	1.0	-0.7
Weight	0.5	2.5	3.1	1.3	1.8
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	0.9	0.9	-0.7
Impedance of arm (left)	0.5	2.4	4.6	-0.4	-2.1
Trunk predicted mass	0.5	2.7	5.2	-0.4	2.3
Loud music exposure frequency	0.5	0.5	0.8	0.5	-0.9
Birth weight	0.5	1.1	1.8	-1.3	0.6
Leg fat percentage (right)	0.5	2.0	3.9	2.0	0.1
Arm fat-free mass (right)	0.5	2.4	4.6	0.5	2.1
Whole body fat mass	0.5	2.0	3.2	1.8	0.9
Leg fat mass (right)	0.5	2.0	3.4	1.9	0.7
Pulse rate, automated reading	0.5	1.8	2.2	1.2	-1.5
Chest pain or discomfort	0.5	0.7	1.3	-0.4	-1.1
Medication: Aspirin	0.5	0.6	1.1	1.1	-0.2
Leg fat-free mass (right)	0.5	2.7	5.2	0.3	2.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	0.9	0.9	0.4
Whole body water mass	0.5	3.0	6.0	0.1	2.4
Leg predicted mass (right)	0.5	2.5	4.9	0.4	2.2
Wears glasses or contact lenses	0.5	0.6	0.9	0.6	-0.9
Eye problems/disorders: Glaucoma	0.5	0.6	0.9	0.6	-1.0
Basal metabolic rate	0.5	2.7	5.2	0.5	2.3
Number of operations (self-reported)	0.5	0.7	1.3	-1.1	0.3
Irritability	0.5	0.9	1.6	-0.4	-1.3
Ever depressed for a whole week	0.5	0.6	1.2	1.1	-0.0
Cholesterol lowering medication	0.5	0.7	1.3	0.1	1.1
Arm predicted mass (left)	0.5	2.6	5.1	0.4	2.3
Depressed Affect (Nagel 2018)	0.4	0.9	1.0	0.9	-1.0
Mean Putamen Volume	0.4	0.4	0.9	0.0	-0.9
Hand grip strength (left)	0.4	1.0	1.9	-0.1	1.4
Relative age of first facial hair	0.4	0.8	1.0	-0.8	1.0
Pack years adult smoking proportion	0.4	0.6	1.2	1.1	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.0	1.0	-0.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	0.5	-0.7	-0.7
Trunk fat mass	0.4	1.9	3.3	1.8	0.7
Number of incorrect matches in round	0.4	0.6	1.0	1.0	0.6
Had other major operations	0.4	0.5	0.6	0.6	-0.8
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.6	0.6	0.8
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.1	0.1	-1.1
Trunk fat-free mass	0.4	2.6	5.1	-0.3	2.2
Alcohol intake versus 10 years previously	0.4	0.6	1.1	-0.1	1.1
Father’s age at death	0.4	0.6	1.0	-0.4	-1.0
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.2	-1.1	0.8
Tense / ‘highly strung’	0.4	0.6	0.9	0.6	-0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.3	-1.2	0.1
Blood clot in the leg (DVT)	0.4	0.5	0.9	-0.3	0.9
Gout (self-reported)	0.4	0.6	0.8	-0.9	-0.7
Migraine (self-reported)	0.4	0.6	1.1	1.1	0.1
Number of full sisters	0.4	0.5	1.0	0.2	-1.0
Had major operations	0.4	0.5	0.8	-0.9	-0.3
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	0.8	0.4	-0.9
Whole body fat-free mass	0.4	2.5	5.1	0.2	2.2
Loneliness, isolation	0.4	0.5	1.0	-0.1	-1.0
Medication for cholesterol	0.4	0.6	1.0	-0.5	-1.0
Medication: Atorvastatin	0.4	0.5	0.6	0.8	0.5
Arm fat-free mass (left)	0.4	1.8	3.3	0.6	1.8
Pain experienced in last month	0.4	0.6	1.2	-1.1	0.2
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.8	0.9	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	0.9	-0.2	1.0
Alcohol drinker status: Previous	0.4	0.5	0.8	-0.4	0.9
Crohns Disease (2017)	0.3	0.7	1.4	-0.1	-1.2
Ovarian Cancer	0.3	0.4	0.5	-0.5	-0.7
Coronary Artery Disease (CAD)	0.3	0.3	0.5	0.4	0.7
HbA1C	0.3	0.4	0.4	-0.6	0.6
HDL Cholesterol	0.3	0.4	0.7	0.4	0.8
Lupus	0.3	0.5	0.5	0.7	-0.7
Blood White Count	0.3	2.2	2.4	1.4	-1.5
Smoking Status	0.3	0.8	1.5	1.2	-0.3
Lung FVC	0.3	1.6	3.2	-1.8	0.2
Chronotype (morning person)	0.3	0.7	1.0	-0.7	1.0
Hair Pigment	0.3	8.8	14.0	1.9	-3.7
Hearing difficulty/problems: Yes	0.3	0.4	0.6	0.5	-0.8
Vitamin and mineral supplements	0.3	0.4	0.8	0.2	-0.9
Serious illness, injury or assault to yourself	0.3	0.3	0.4	0.5	0.6
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.4	0.6	-0.6
Had menopause	0.3	0.3	0.5	-0.7	0.3
Time employed in main current job	0.3	0.3	0.4	0.7	0.5
Medication: Cholesterol lowering	0.3	0.4	0.8	0.9	-0.1
Exposure to tobacco smoke at home	0.3	0.3	0.3	0.6	-0.5
Number of full brothers	0.3	0.4	0.8	0.9	0.3
Pulse wave peak to peak time	0.3	0.3	0.5	-0.3	0.7
Eye problems/disorders: None of the above	0.3	0.3	0.6	0.8	-0.1
Overall health rating	0.3	0.6	0.9	1.0	-0.5
Average weekly red wine intake	0.3	0.4	0.8	-0.2	0.9
High cholesterol (Self-reported)	0.3	0.5	0.5	0.7	-0.7
Ever smoked	0.3	0.6	1.0	-1.0	0.3
Ever had prostate specific antigen (PSA) test	0.3	0.4	0.8	-0.0	-0.9
Intelligence (Savage-Jansen 2018)	0.2	0.5	0.8	-0.5	-0.9
Major Depression (MDD)	0.2	0.2	0.3	-0.4	-0.6
Verbal and Numeric Reasoning (VNR)	0.2	0.4	0.6	0.5	-0.8
Fasting Glucose	0.2	0.3	0.4	-0.6	-0.4
Blood Platelet Count	0.2	2.3	4.1	2.0	-0.7
Type 2 Diabetes (T2D) (2018)	0.2	0.5	0.9	0.9	-0.1
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.5	0.7	0.3
Diabetes (mother)	0.2	0.3	0.5	0.7	0.4
Medication: Atenolol	0.2	0.2	0.3	-0.3	0.5
Hearing difficulty/problems with background noise	0.2	0.4	0.8	0.9	0.2
Illnesses of siblings	0.2	0.4	0.6	-0.8	-0.3
Hair/balding pattern: Pattern 3	0.2	0.3	0.6	-0.1	0.8
Noisy workplace	0.2	0.3	0.5	0.4	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	-0.2	0.6
Depression (self-reported)	0.2	0.2	0.4	0.7	-0.2
Pulse wave Arterial Stiffness index	0.2	0.2	0.5	0.1	-0.7
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.4	0.6	0.2
Medication: Paracetamol	0.2	0.4	0.6	-0.7	-0.5
Medication: Amlodipine	0.2	0.2	0.3	0.5	0.4
Number of children fathered	0.2	0.2	0.4	-0.6	0.0
Medication: Blood pressure	0.2	0.4	0.6	0.8	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.6	-0.8	0.2
Diabetes diagnosed by doctor	0.2	0.3	0.5	0.7	0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	0.5	-0.5	0.7
Mineral and other dietary supplements	0.2	0.3	0.6	-0.8	-0.1
Osteoarthritis (self-reported)	0.2	0.3	0.5	0.3	-0.7
Mother’s age at death	0.2	0.2	0.4	-0.6	0.1
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.3	-0.6	-0.6
Age started oral contraceptive pill	0.2	0.2	0.5	0.1	0.7
Commuting to job workplace: Cycle	0.2	0.3	0.6	-0.0	-0.8
Pack years of smoking	0.2	0.3	0.6	0.8	-0.3
Bipolar Disorder (2018)	0.1	0.1	0.2	-0.1	0.4
Schizophrenia (2018)	0.1	0.2	0.2	-0.4	-0.4
Irritable Bowel Disease (IBD)	0.1	0.3	0.7	0.1	-0.8
Ulcerative Colitis (UC)	0.1	0.3	0.5	0.7	-0.2
Schizophrenia (2014)	0.1	0.3	0.5	-0.2	-0.7
Blood Red Count	0.1	0.9	1.1	-0.9	1.0
Waist Hip Ratio (WHR)	0.1	0.3	0.4	0.5	-0.6
Systolic Blood Pressure	0.1	0.6	1.2	-1.1	0.2
Cardiovascular Disease	0.1	0.3	0.5	-0.1	0.7
Systolic blood pressure, automated reading	0.1	0.4	0.4	0.6	0.6
Angina	0.1	0.1	0.3	-0.5	0.1
Townsend deprivation index at recruitment	0.1	0.1	0.2	-0.1	-0.4
Age when periods started (menarche)	0.1	0.2	0.2	-0.4	-0.4
Multivitamins +/- minerals	0.1	0.1	0.1	-0.2	-0.3
Medication: Levothyroxine sodium	0.1	0.2	0.3	0.3	0.6
Sitting height	0.1	0.7	1.1	-1.0	0.6
High blood pressure (mother)	0.1	0.1	0.2	0.2	-0.5
Diabetes (self-reported)	0.1	0.2	0.2	0.5	0.4
Fluid intelligence score	0.1	0.2	0.3	0.3	-0.5
Mouth/teeth dental problems: Dentures	0.1	0.2	0.4	-0.1	0.7
Standing height	0.1	0.6	1.1	-1.1	0.3
Pulse wave reflection index	0.1	0.1	0.2	0.2	0.4
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.3	-0.4	-0.5
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.2	0.1	0.5
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.1	0.3	0.1
High blood pressure (siblings)	0.1	0.2	0.2	0.3	0.5
Age at first live birth	0.1	0.3	0.5	0.0	0.7
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	0.2	-0.4
Emphysema/chronic bronchitis	0.1	0.2	0.2	0.5	0.3
Angina (self-reported)	0.1	0.1	0.1	-0.2	-0.3
Medication: Allopurinol	0.1	0.2	0.3	-0.1	0.6
Mean time to correctly identify matches	0.1	0.2	0.5	-0.7	0.0
Alcohol intake frequency.	0.1	0.2	0.3	0.6	0.2
Comparative height size at age 10	0.1	0.4	0.6	0.8	0.5
Smoking status: Previous	0.1	0.1	0.3	-0.5	-0.0
Qualifications: nursing, teaching	0.1	0.2	0.3	-0.2	0.6
Eye problems/disorders: Cataract	0.1	0.1	0.1	0.1	-0.4
Breast cancer (self-reported)	0.1	0.1	0.2	-0.5	0.2
Medication: Gliclazide	0.1	0.1	0.2	-0.5	0.0
Guilty feelings	0.1	0.1	0.3	0.0	-0.5
Medication: Paracetamol	0.1	0.2	0.4	-0.6	0.0
Risk taking	0.1	0.2	0.2	-0.4	0.4
Unable to work because of sickness or disability	0.1	0.1	0.1	-0.1	-0.4
Bipolar Disorder or Schizophrenia	0.0	0.0	0.1	-0.2	-0.1
Breast Cancer	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.1	0.1	-0.2	0.3
Crohns Disease (2012)	0.0	0.1	0.1	-0.4	-0.1
LDL Cholesterol	0.0	0.0	0.1	-0.2	-0.2
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.2	-0.0
Ulcerative Colitis	0.0	0.0	0.1	0.2	0.2
Blood Eosinophil Count	0.0	0.4	0.5	0.7	-0.5
Height	0.0	0.9	1.1	-1.1	-0.8
Hypothyroidism (self reported)	0.0	0.1	0.1	0.3	0.2
Average weekly fortified wine intake	0.0	0.1	0.1	0.0	-0.3
Qualifications: CSEs or equivalent	0.0	0.0	0.0	-0.2	0.0
High blood pressure	0.0	0.1	0.2	0.1	-0.4
Past tobacco smoking	0.0	0.0	0.1	0.3	0.0
Medication: Simvastatin	0.0	0.1	0.1	0.3	0.1
Length of working week for main job	0.0	0.1	0.1	0.3	0.2
Qualifications: College or University degree	0.0	0.2	0.3	-0.0	-0.6
Medication for pain relief, constipation, heartburn	0.0	0.1	0.2	0.1	0.4
Medication: Seretide 50 evohaler	0.0	0.0	0.0	-0.1	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.1	0.1	0.3	0.1
Hypertension (Self-reported)	0.0	0.1	0.2	0.1	0.4
Hearing aid user	0.0	0.0	0.1	-0.2	0.2
Medication: Blood pressure	0.0	0.1	0.2	-0.4	0.1
Medication: Bendroflumethiazide	0.0	0.0	0.1	-0.2	-0.1
Fractured/broken bones in last 5 years	0.0	0.0	0.1	-0.1	-0.3
Diastolic blood pressure, automated reading	0.0	0.0	0.1	-0.3	-0.0
Vascular/heart problems diagnosed by doctor	0.0	0.0	0.0	-0.2	0.1

Hub : Genes

KRT6A

Models

Trait associations