TWAS hub - LLPH

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Testis	0.1900	0.0640	7.4e-04	0.210	NA	0.185	NA	0.196	1.1e-09	NA	1.2e-08	NA	4.3e-09
2	TCGA	Breast Invasive Carcinoma	0.0541	0.0188	2.2e-16	0.093	0.091	0.094	NA	0.092	2.0e-18	4.5e-18	1.2e-18	NA	2.4e-18
3	TCGA	Colon Adenocarcinoma	0.1360	0.0670	9.7e-06	0.124	0.081	0.101	NA	0.102	1.2e-07	2.1e-05	2.0e-06	NA	1.6e-06
4	TCGA	Head and Neck Squamous Cell Carcinoma	0.0364	0.0223	1.9e-03	0.014	0.014	0.008	NA	0.010	9.7e-03	8.3e-03	3.7e-02	NA	2.5e-02
5	TCGA	Kidney Renal Clear Cell Carcinoma	0.1193	0.0375	0.0e+00	0.178	0.180	0.186	NA	0.187	1.2e-19	7.2e-20	1.8e-20	NA	1.3e-20
6	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1710	0.0570	1.4e-10	0.161	0.201	0.212	NA	0.195	1.7e-09	1.0e-11	2.7e-12	NA	2.2e-11
7	TCGA	Brain Lower Grade Glioma	0.1641	0.0524	0.0e+00	0.195	0.200	0.200	NA	0.202	1.0e-21	2.9e-22	2.7e-22	NA	1.8e-22
8	TCGA	Liver Hepatocellular Carcinoma	0.1390	0.0710	4.0e-05	0.110	0.090	0.083	NA	0.109	7.7e-06	5.3e-05	9.5e-05	NA	8.5e-06
9	TCGA	Lung Adenocarcinoma	0.0936	0.0335	7.7e-14	0.127	0.132	0.131	NA	0.132	1.1e-14	3.5e-15	4.7e-15	NA	3.4e-15
10	TCGA	Lung Squamous Cell Carcinoma	0.0439	0.0252	4.4e-04	0.032	0.019	0.012	NA	0.018	1.4e-04	2.8e-03	1.3e-02	NA	3.7e-03
11	TCGA	Ovarian Serous Cystadenocarcinoma	0.0450	0.0270	5.3e-03	0.050	0.027	0.015	NA	0.034	2.5e-04	5.7e-03	3.2e-02	NA	2.4e-03
12	TCGA	Pancreatic Adenocarcinoma	0.1910	0.0850	1.6e-05	0.106	0.121	0.081	NA	0.107	3.3e-05	9.2e-06	2.7e-04	NA	3.0e-05
13	TCGA	Pheochromocytoma and Paraganglioma	0.2510	0.0930	8.8e-09	0.237	0.223	0.250	NA	0.249	7.7e-10	2.7e-09	2.3e-10	NA	2.4e-10
14	TCGA	Prostate Adenocarcinoma	0.2365	0.0679	0.0e+00	0.261	0.253	0.256	NA	0.263	3.1e-27	3.0e-26	1.3e-26	NA	2.0e-27
15	TCGA	Rectum Adenocarcinoma	0.1460	0.0790	4.6e-03	0.104	0.034	0.040	NA	0.085	2.0e-03	5.4e-02	4.1e-02	NA	5.1e-03
16	TCGA	Testicular Germ Cell Tumors	0.3910	0.1170	1.1e-11	0.320	0.290	0.308	NA	0.310	5.3e-12	8.1e-11	1.7e-11	NA	1.3e-11
17	TCGA	Thyroid Carcinoma	0.3480	0.0780	0.0e+00	0.447	0.430	0.453	NA	0.460	8.8e-48	1.9e-45	1.1e-48	NA	1.1e-49
18	TCGA	Uterine Corpus Endometrial Carcinoma	0.1160	0.0620	6.5e-03	0.119	0.074	0.090	NA	0.089	3.4e-04	4.3e-03	1.7e-03	NA	1.9e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Osteoporosis (self-reported)	8.6	10.7	14.4	-3.2	-3.5	-3.1	-2.9	-3.3	-2.7	-3.6	-3.6	-3.4	-3.1	-3.3	-2.6	-3.6	-3.2	-3.0	-3.8	-3.3	-3.4
Severe depression (siblings)	6.0	6.7	8.0	2.7	2.8	2.6	2.1	2.4	2.6	2.7	2.7	2.7	2.7	2.6	2.2	2.7	2.7	2.5	2.4	2.5	2.8
Eye problems/disorders: Cataract	4.5	5.3	7.8	-2.1	-2.3	-2.2	-2.0	-2.4	-2.3	-2.1	-2.4	-2.3	-2.4	-2.1	-2.3	-2.0	-2.2	-2.8	-2.6	-2.3	-2.2
Ever had hysterectomy (womb removed)	4.0	4.5	6.9	-1.9	-2.3	-2.1	-1.8	-2.2	-2.2	-2.1	-2.0	-2.1	-2.1	-2.1	-2.3	-2.0	-2.1	-2.6	-1.9	-2.2	-2.1
Bilateral oophorectomy (both ovaries removed)	3.9	4.5	7.1	-2.4	-2.2	-1.9	-1.9	-1.9	-2.0	-2.2	-2.2	-2.2	-2.2	-2.0	-1.6	-2.1	-2.0	-2.7	-2.3	-2.0	-2.1
Height	3.8	73.2	95.5	7.7	7.7	8.8	8.7	8.7	6.9	9.2	8.9	8.0	9.0	8.8	9.8	9.7	8.9	5.4	8.5	8.9	9.3
Standing height	3.6	35.7	50.1	6.0	5.2	5.8	6.5	5.9	4.2	6.7	6.2	5.5	6.2	6.0	6.4	7.1	6.1	3.6	6.3	6.1	6.5
Illnesses of siblings: Diabetes	3.5	4.3	5.4	-2.0	-2.3	-2.1	-1.7	-2.0	-2.3	-2.0	-2.2	-2.2	-1.9	-2.1	-2.0	-1.9	-2.1	-2.1	-2.1	-2.1	-2.1
Average weekly champagne plus white wine intake	3.5	4.8	5.8	2.0	2.4	2.2	2.0	2.2	1.9	2.4	2.2	2.4	2.3	2.2	1.8	2.4	2.2	1.9	2.3	2.3	2.3
Medication: Gliclazide	3.4	3.9	5.2	-1.8	-1.9	-1.9	-2.0	-2.1	-1.6	-2.1	-1.9	-1.9	-2.3	-1.9	-1.7	-2.1	-1.9	-2.0	-2.1	-2.0	-2.0
Average weekly beer plus cider intake	3.3	4.7	6.8	-1.7	-2.0	-2.0	-2.6	-2.3	-1.5	-2.2	-2.1	-2.0	-2.4	-2.1	-2.6	-2.4	-2.1	-1.8	-2.3	-2.3	-2.3
Medication: Metformin	3.2	4.5	6.1	-2.1	-2.2	-1.9	-2.3	-2.1	-1.6	-2.2	-2.0	-2.1	-2.4	-2.0	-1.8	-2.3	-2.0	-2.5	-2.3	-2.1	-2.2
Glaucoma (self-reported)	3.2	3.8	4.8	1.5	2.0	2.2	1.3	2.2	1.9	2.1	2.0	2.0	2.0	2.2	1.8	2.1	2.2	1.5	1.9	2.1	2.1
Leg fat percentage (right)	3.2	11.5	14.2	-3.8	-3.5	-3.4	-3.2	-3.1	-3.6	-3.5	-3.3	-3.6	-3.3	-3.4	-3.6	-3.2	-3.4	-2.9	-3.3	-3.4	-3.5
Leg fat percentage (left)	3.2	11.7	14.2	-3.8	-3.6	-3.4	-3.2	-3.1	-3.6	-3.5	-3.4	-3.6	-3.3	-3.4	-3.6	-3.2	-3.5	-3.0	-3.4	-3.4	-3.5
Mouth/teeth dental problems: Loose teeth	3.1	3.7	5.1	-1.4	-1.8	-2.2	-1.2	-2.2	-1.9	-2.0	-2.0	-1.8	-2.2	-2.1	-1.8	-2.1	-2.1	-1.9	-1.5	-2.1	-2.1
Sitting height	3.0	21.6	32.9	4.6	3.9	4.5	5.3	4.5	3.1	5.2	4.9	4.1	5.0	4.6	5.2	5.7	4.7	2.6	4.8	4.7	5.2
Had menopause	2.8	3.5	6.7	-2.1	-1.7	-1.6	-2.6	-1.7	-1.6	-1.7	-1.9	-1.7	-2.1	-1.6	-2.3	-1.7	-1.6	-1.6	-2.1	-1.8	-1.8
Number of full brothers	2.8	3.5	4.4	-2.1	-2.1	-1.8	-1.6	-1.8	-2.1	-1.9	-2.0	-2.1	-1.6	-1.9	-2.0	-1.6	-1.9	-1.5	-2.0	-1.9	-1.8
Blood White Count	2.7	19.8	23.4	-4.2	-4.5	-4.6	-3.7	-4.5	-4.3	-4.7	-4.8	-4.5	-4.7	-4.6	-4.0	-4.8	-4.7	-3.8	-4.3	-4.6	-4.8
Eye problems/disorders: Diabetes related eye disease	2.7	3.0	4.3	-2.0	-1.9	-1.5	-1.6	-1.5	-1.8	-1.7	-1.8	-1.9	-1.6	-1.6	-1.6	-1.6	-1.7	-1.8	-2.1	-1.7	-1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	2.7	4.1	4.9	-1.7	-2.1	-2.1	-1.8	-2.1	-2.2	-2.0	-2.0	-2.1	-2.2	-2.0	-2.0	-1.8	-2.0	-2.1	-2.1	-2.1	-2.0
Depression (self-reported)	2.6	3.2	4.0	-1.5	-2.0	-1.9	-1.1	-1.8	-1.8	-2.0	-1.7	-2.0	-1.7	-2.0	-1.2	-1.9	-1.9	-1.9	-1.6	-1.8	-1.9
Commuting to job workplace: Walk	2.5	2.7	4.0	1.1	1.7	2.0	0.7	1.8	2.0	1.7	1.9	1.8	1.2	2.0	1.8	1.7	1.9	0.7	1.2	1.8	1.8
Pulse wave peak to peak time	2.4	2.8	5.5	1.8	1.8	1.4	2.0	1.4	0.7	2.0	1.7	1.6	1.8	1.5	0.6	2.4	1.4	1.8	2.0	1.6	1.8
Migraine (self-reported)	2.3	2.9	3.8	1.3	1.6	1.9	1.3	1.9	1.6	1.8	1.5	1.8	1.6	1.9	1.9	1.8	1.9	1.0	1.4	1.9	1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.3	2.7	3.9	-1.6	-1.6	-1.4	-2.0	-1.5	-1.5	-1.6	-1.8	-1.6	-1.8	-1.5	-1.8	-1.6	-1.5	-1.6	-1.9	-1.6	-1.6
HbA1C	2.2	2.4	4.4	-0.9	-1.2	-1.9	-1.6	-1.7	-1.5	-1.6	-1.6	-1.3	-1.9	-1.7	-2.1	-1.7	-1.7	-0.7	-1.1	-1.6	-1.7
Exposure to tobacco smoke outside home	2.1	2.8	4.7	1.6	1.9	1.5	1.4	1.7	1.8	1.5	1.7	1.7	1.4	1.5	2.1	1.3	1.6	1.8	2.2	1.7	1.5
Alzheimer’s Disease (including proxy)	2.0	2.8	4.4	1.4	1.6	2.1	1.0	1.7	1.9	1.8	1.4	1.8	1.6	2.0	1.7	1.7	1.9	1.5	1.0	1.8	1.8
Knee pain experienced in last month	2.0	3.2	4.5	1.4	1.7	2.0	1.1	2.1	1.7	1.8	1.8	1.8	1.7	2.0	1.8	1.8	2.0	1.5	1.7	2.1	1.9
Tense / ‘highly strung’	1.9	3.2	4.5	-0.8	-2.0	-2.1	-1.0	-1.9	-2.1	-1.8	-1.8	-2.0	-1.9	-2.0	-1.4	-1.7	-2.0	-2.0	-1.4	-1.8	-1.9
Comparative height size at age 10	1.9	10.3	12.7	2.7	2.8	3.4	3.0	3.5	2.7	3.4	3.3	2.9	3.5	3.3	3.6	3.6	3.4	2.3	3.2	3.5	3.5
Wears glasses or contact lenses	1.9	2.1	2.9	-1.7	-1.6	-1.4	-1.2	-1.4	-1.6	-1.4	-1.6	-1.6	-1.3	-1.4	-1.5	-1.2	-1.4	-1.3	-1.7	-1.5	-1.4
Hearing difficulty/problems: Yes	1.8	2.7	3.9	-1.3	-1.8	-1.6	-1.4	-1.8	-2.0	-1.5	-1.6	-1.8	-1.5	-1.6	-1.7	-1.2	-1.6	-1.9	-1.7	-1.8	-1.5
Diabetes (mother)	1.8	2.3	3.7	-1.8	-1.4	-1.4	-1.9	-1.3	-0.9	-1.8	-1.5	-1.5	-1.5	-1.5	-1.5	-1.9	-1.5	-0.9	-1.6	-1.4	-1.7
Body mass index (BMI)	1.8	7.7	10.6	-3.3	-2.8	-2.7	-2.9	-2.4	-2.7	-2.9	-2.7	-2.9	-2.9	-2.7	-2.8	-2.8	-2.8	-2.2	-2.9	-2.7	-2.9
Body fat percentage	1.8	7.1	10.5	-3.2	-2.7	-2.5	-2.8	-2.2	-2.6	-2.8	-2.6	-2.8	-2.7	-2.5	-2.7	-2.6	-2.6	-2.3	-2.8	-2.5	-2.7
Pulse rate, automated reading	1.8	5.9	9.9	3.2	2.5	2.3	2.6	2.0	2.2	2.7	2.4	2.6	2.1	2.4	2.6	2.6	2.4	1.3	2.3	2.4	2.5
Average weekly red wine intake	1.8	2.6	4.6	1.5	1.7	1.6	1.4	1.5	1.2	1.9	1.6	1.7	1.9	1.7	0.9	2.1	1.7	1.5	1.6	1.6	1.8
Worry (Nagel 2018)	1.7	3.6	4.3	-1.1	-1.9	-1.9	-1.7	-2.1	-1.7	-1.9	-2.0	-1.8	-2.1	-1.9	-2.0	-1.9	-1.9	-2.1	-2.0	-1.9	-2.0
Fluid intelligence score	1.7	3.6	4.8	1.5	1.7	2.1	1.7	2.0	1.7	2.1	1.9	1.9	2.2	2.1	1.7	2.2	2.0	1.4	1.6	2.0	2.0
Illnesses of mother	1.7	2.1	3.1	1.0	1.5	1.5	1.1	1.5	1.7	1.3	1.8	1.5	1.4	1.4	1.4	1.2	1.4	1.5	1.7	1.4	1.4
Qualifications: O levels/GCSEs or equivalent	1.7	2.6	4.4	1.8	1.8	1.6	1.4	1.4	1.4	1.8	1.9	1.7	1.4	1.6	1.4	1.8	1.6	1.1	2.1	1.6	1.7
Blood clot in the leg (DVT)	1.7	2.2	3.9	-1.8	-1.7	-1.2	-1.6	-1.2	-1.3	-1.4	-1.4	-1.5	-2.0	-1.2	-0.9	-1.4	-1.3	-2.0	-1.8	-1.3	-1.5
Heart disease (mother)	1.7	2.1	2.7	-1.4	-1.3	-1.4	-1.4	-1.4	-1.4	-1.4	-1.6	-1.4	-1.5	-1.4	-1.6	-1.4	-1.4	-1.1	-1.5	-1.4	-1.5
Major Depression (MDD)	1.6	1.9	2.7	-0.6	-1.5	-1.6	-0.4	-1.6	-1.4	-1.5	-1.4	-1.5	-1.3	-1.6	-1.0	-1.5	-1.6	-1.2	-1.2	-1.6	-1.5
Ovarian Cancer	1.6	2.1	3.1	-1.6	-1.6	-1.3	-1.5	-1.4	-1.5	-1.4	-1.5	-1.5	-1.3	-1.4	-1.8	-1.3	-1.4	-0.9	-1.6	-1.4	-1.4
Medication: Atenolol	1.6	2.0	4.5	-2.1	-1.4	-1.0	-2.1	-1.0	-0.6	-1.6	-1.3	-1.3	-1.5	-1.1	-1.2	-1.7	-1.2	-0.9	-1.9	-1.3	-1.5
Overall health rating	1.6	3.4	4.1	-1.9	-1.9	-1.8	-1.5	-1.9	-1.7	-2.0	-1.7	-2.0	-2.0	-1.9	-1.3	-1.9	-1.9	-2.0	-1.9	-1.9	-1.9
Leg pain on walking	1.6	2.0	3.2	-1.8	-1.5	-1.2	-1.6	-1.2	-1.2	-1.6	-1.5	-1.5	-1.2	-1.4	-1.5	-1.5	-1.4	-0.7	-1.7	-1.4	-1.5
Heart disease (siblings)	1.6	2.0	3.4	-1.5	-1.3	-1.2	-1.8	-1.3	-0.9	-1.4	-1.4	-1.3	-1.5	-1.2	-1.6	-1.5	-1.3	-1.2	-1.7	-1.4	-1.4
Birth weight	1.5	3.2	4.6	1.3	1.5	2.0	1.8	1.9	1.4	1.9	1.7	1.6	2.1	2.0	2.1	2.1	2.0	1.2	1.2	1.9	2.0
Reaction Time	1.4	2.7	4.2	-1.5	-1.3	-1.7	-1.7	-1.6	-1.5	-1.7	-1.6	-1.4	-2.0	-1.6	-2.1	-1.8	-1.7	-1.0	-1.5	-1.7	-1.8
Trunk fat percentage	1.4	5.6	9.1	-3.0	-2.5	-2.1	-2.6	-1.9	-2.2	-2.5	-2.3	-2.5	-2.5	-2.2	-2.4	-2.4	-2.2	-2.1	-2.5	-2.2	-2.4
Medication: Levothyroxine sodium	1.4	2.3	3.0	-1.7	-1.6	-1.4	-1.3	-1.4	-1.3	-1.7	-1.6	-1.6	-1.5	-1.5	-1.2	-1.7	-1.5	-1.4	-1.7	-1.5	-1.6
Hair/balding pattern: Pattern 2	1.4	1.8	4.0	-2.0	-1.1	-1.1	-1.7	-1.1	-0.3	-1.7	-1.3	-1.2	-1.3	-1.2	-0.9	-2.0	-1.2	-0.6	-1.6	-1.2	-1.5
Forced vital capacity (FVC)	1.4	5.6	13.4	3.7	2.4	1.5	3.4	1.5	1.3	2.5	2.3	2.3	2.4	1.7	2.0	2.5	1.9	1.9	3.3	1.9	2.3
Trunk predicted mass	1.4	8.1	13.5	2.6	2.3	2.8	3.2	2.9	1.5	3.3	3.0	2.5	3.0	2.9	3.1	3.7	2.9	1.5	3.0	2.9	3.2
Mean time to correctly identify matches	1.4	2.8	4.4	-1.7	-1.3	-1.6	-1.9	-1.6	-1.4	-1.8	-1.6	-1.5	-1.9	-1.7	-2.1	-1.8	-1.7	-1.0	-1.6	-1.7	-1.8
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	3.1	-1.6	-1.5	-1.1	-1.4	-1.1	-1.2	-1.3	-1.2	-1.3	-1.7	-1.1	-0.9	-1.2	-1.2	-1.8	-1.6	-1.2	-1.3
Primary Biliary Cirrhosis	1.3	1.8	3.2	1.0	1.8	1.5	0.5	1.4	1.8	1.3	1.3	1.6	1.1	1.4	0.8	1.1	1.4	1.7	1.2	1.4	1.3
Supplements: Zinc	1.3	1.4	2.2	-0.5	-1.0	-1.4	-0.5	-1.5	-1.1	-1.2	-1.3	-1.1	-1.3	-1.3	-0.8	-1.3	-1.3	-1.1	-1.0	-1.4	-1.3
Average weekly fortified wine intake	1.3	1.5	1.8	1.1	1.3	1.2	1.2	1.4	1.1	1.3	1.2	1.3	1.2	1.3	1.1	1.3	1.2	1.2	1.1	1.3	1.2
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	1.9	-1.2	-1.1	-1.2	-1.2	-1.0	-1.0	-1.3	-1.2	-1.1	-1.4	-1.2	-1.2	-1.4	-1.3	-0.7	-1.4	-1.2	-1.4
Trunk fat-free mass	1.3	7.6	12.9	2.6	2.2	2.7	3.1	2.9	1.4	3.2	2.9	2.4	2.9	2.8	3.0	3.6	2.8	1.4	2.9	2.8	3.1
Forced expiratory volume in 1-second (FEV1)	1.3	4.4	12.8	3.6	2.0	1.1	3.2	1.1	1.1	2.3	2.0	2.0	2.0	1.4	1.7	2.2	1.6	1.5	3.0	1.6	2.0
Pulse rate	1.3	2.2	4.8	2.2	1.4	1.3	1.9	1.1	1.1	1.6	1.4	1.4	1.3	1.3	1.8	1.6	1.3	0.8	1.4	1.4	1.6
Prospective memory result	1.3	1.6	3.4	-1.7	-1.2	-1.2	-1.7	-1.0	-0.5	-1.5	-1.2	-1.1	-1.5	-1.1	-0.9	-1.8	-1.1	-0.8	-1.3	-1.2	-1.5
Shortness of breath walking on level ground	1.3	1.6	2.7	-1.1	-1.1	-1.4	-1.1	-1.4	-0.9	-1.5	-1.4	-1.2	-1.2	-1.4	-1.1	-1.6	-1.4	-0.4	-1.2	-1.4	-1.4
Emphysema/chronic bronchitis	1.3	1.5	1.9	-1.2	-1.2	-1.4	-0.8	-1.3	-1.3	-1.3	-1.3	-1.2	-1.1	-1.4	-1.4	-1.3	-1.4	-0.7	-0.9	-1.3	-1.3
Mood swings	1.3	2.3	5.6	-0.9	-1.8	-1.5	-0.9	-1.6	-1.8	-1.4	-1.6	-1.6	-1.7	-1.5	-0.8	-1.3	-1.4	-2.4	-1.6	-1.5	-1.4
Medication: Atorvastatin	1.3	1.6	2.5	0.7	1.4	1.5	0.6	1.3	1.5	1.4	1.1	1.5	1.1	1.6	1.1	1.3	1.5	0.9	0.7	1.3	1.4
Commuting to job workplace: Cycle	1.3	1.6	2.4	1.4	1.1	1.0	1.4	1.2	0.9	1.3	1.2	1.2	1.5	1.1	0.9	1.4	1.2	1.5	1.5	1.3	1.3
Triglycerides	1.2	2.0	2.4	-1.4	-1.4	-1.4	-1.1	-1.5	-1.3	-1.5	-1.5	-1.4	-1.4	-1.5	-1.2	-1.5	-1.5	-1.5	-1.5	-1.5	-1.4
Mouth/teeth dental problems: Dentures	1.2	2.0	2.5	1.4	1.3	1.4	1.3	1.5	1.4	1.6	1.5	1.5	1.4	1.6	1.3	1.5	1.5	1.0	1.2	1.5	1.5
Pulse wave Arterial Stiffness index	1.2	1.4	2.9	-1.2	-1.4	-0.9	-1.3	-0.9	-0.5	-1.5	-1.1	-1.2	-1.2	-1.0	-0.0	-1.7	-0.9	-1.5	-1.5	-1.1	-1.3
Suffer from ‘nerves’	1.2	1.9	7.0	0.3	-1.5	-1.5	-0.3	-1.8	-1.9	-0.8	-1.3	-1.3	-1.5	-1.3	-1.1	-0.6	-1.3	-2.6	-1.1	-1.4	-1.0
Long-standing illness, disability or infirmity	1.2	1.8	3.0	-1.7	-1.5	-1.2	-1.3	-1.2	-1.1	-1.4	-1.3	-1.4	-1.3	-1.2	-1.0	-1.3	-1.2	-1.5	-1.7	-1.3	-1.3
Illnesses of siblings	1.1	1.5	2.7	1.3	1.2	1.3	1.3	1.1	1.1	1.3	1.2	1.3	1.1	1.3	1.6	1.3	1.3	0.6	1.3	1.2	1.3
Arm fat percentage (right)	1.1	4.2	6.3	-2.5	-2.1	-2.0	-2.2	-1.7	-2.0	-2.2	-2.0	-2.1	-2.1	-2.0	-2.0	-2.1	-2.0	-1.6	-2.2	-1.9	-2.1
Medication: Co-codamol	1.0	1.2	2.1	1.4	0.9	0.9	1.5	1.0	0.7	1.3	0.9	1.1	0.9	1.1	1.3	1.2	1.1	0.3	1.1	1.2	1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	5.3	1.6	1.2	0.9	2.3	1.3	0.6	1.4	1.3	1.2	1.9	1.0	1.2	1.6	1.1	2.0	2.0	1.3	1.4
Alcohol usually taken with meals	1.0	1.6	2.5	1.4	1.5	1.1	1.4	0.9	0.8	1.5	1.2	1.4	1.4	1.1	0.7	1.6	1.2	1.2	1.5	1.1	1.4
Noisy workplace	1.0	1.2	2.4	-1.2	-0.9	-0.9	-1.4	-0.9	-0.5	-1.4	-1.1	-1.0	-1.2	-1.0	-0.8	-1.6	-1.0	-0.5	-1.3	-1.0	-1.2
Peak expiratory flow (PEF)	1.0	2.4	5.9	2.4	1.5	0.9	2.2	1.0	0.7	1.7	1.6	1.5	1.5	1.2	1.1	1.8	1.3	1.1	2.3	1.3	1.5
Wheeze or whistling in the chest in last year	1.0	1.7	4.0	-1.5	-0.9	-1.1	-2.0	-1.3	-0.6	-1.3	-1.1	-1.0	-1.6	-1.0	-1.7	-1.4	-1.1	-1.0	-1.5	-1.3	-1.3
Whole body fat-free mass	1.0	5.7	9.4	2.1	1.9	2.4	2.6	2.5	1.3	2.8	2.5	2.0	2.4	2.5	2.8	3.1	2.5	1.1	2.5	2.5	2.7
Arm fat percentage (left)	1.0	3.8	6.1	-2.5	-2.0	-1.9	-2.1	-1.6	-1.7	-2.1	-1.9	-2.0	-2.1	-1.9	-1.7	-2.1	-1.9	-1.5	-2.0	-1.8	-2.1
Illnesses of father: None of the above (group 1)	1.0	1.2	2.2	1.2	0.9	0.9	1.5	1.0	0.9	0.9	0.9	0.9	1.4	0.9	1.4	0.9	0.9	1.5	1.2	1.0	1.0
Whole body water mass	1.0	5.4	9.0	2.0	1.8	2.3	2.5	2.5	1.3	2.7	2.5	2.0	2.4	2.4	2.7	3.0	2.4	1.1	2.4	2.4	2.6
Blood Eosinophil Count	0.9	7.1	11.4	-3.3	-2.3	-2.3	-3.4	-2.3	-1.4	-3.0	-2.6	-2.3	-3.0	-2.4	-2.5	-3.4	-2.4	-1.8	-3.0	-2.5	-3.0
Number of incorrect matches in round	0.9	1.5	2.1	-1.4	-1.4	-1.2	-0.9	-1.1	-1.3	-1.4	-1.2	-1.4	-1.0	-1.2	-1.0	-1.2	-1.2	-0.9	-1.2	-1.2	-1.2
Pain all over the body in last month	0.9	1.0	3.3	-0.6	-1.3	-0.9	-0.2	-1.2	-1.3	-0.7	-1.2	-1.0	-0.6	-0.9	-0.6	-0.5	-0.9	-1.8	-1.1	-1.0	-0.7
Diabetes (self-reported)	0.9	1.4	3.0	-1.2	-1.1	-1.0	-1.2	-1.2	-0.7	-1.2	-1.1	-1.1	-1.5	-1.0	-0.4	-1.4	-1.0	-1.7	-1.3	-1.1	-1.2
Falls in the last year	0.9	1.2	1.7	-0.9	-1.2	-1.1	-1.0	-1.1	-1.2	-1.0	-1.1	-1.1	-1.2	-1.0	-1.1	-0.9	-1.0	-1.3	-1.3	-1.1	-1.1
Impedance of arm (left)	0.9	4.2	6.0	2.2	2.1	1.9	2.1	2.0	2.4	1.8	2.0	2.1	2.0	1.9	2.5	1.5	2.0	1.9	2.2	2.1	1.9
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.2	1.3	1.0	0.8	1.3	1.0	0.9	0.9	1.1	0.9	0.9	0.9	1.5	0.8	0.9	1.0	1.2	1.0	0.9
Eye problems/disorders: None of the above	0.9	1.0	2.6	0.3	1.1	1.2	-0.0	1.2	1.6	0.7	1.0	1.1	0.8	1.1	0.9	0.4	1.1	1.4	0.7	1.1	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	1.4	-0.8	-0.9	-1.1	-0.7	-1.1	-1.0	-1.1	-1.1	-1.0	-0.7	-1.2	-1.2	-1.1	-1.2	-0.5	-1.0	-1.1	-1.1
Leg fat mass (right)	0.9	3.5	5.6	-2.4	-2.0	-1.7	-1.9	-1.5	-2.1	-1.8	-1.8	-2.0	-1.9	-1.8	-1.9	-1.6	-1.8	-1.7	-1.9	-1.8	-1.9
Handedness (chirality/laterality): Left-handed	0.9	1.0	2.1	-0.5	-1.0	-1.5	-0.2	-1.2	-1.0	-1.2	-0.9	-1.2	-0.9	-1.4	-0.7	-1.2	-1.3	-0.1	-0.3	-1.1	-1.1
Number of self-reported non-cancer illnesses	0.9	1.5	2.6	1.2	1.0	1.2	1.6	1.2	0.8	1.4	1.2	1.1	1.3	1.3	1.4	1.6	1.2	0.5	1.2	1.3	1.4
Medication: Bendroflumethiazide	0.9	1.4	2.1	1.2	1.2	1.0	1.3	1.0	1.0	1.3	1.5	1.2	1.1	1.2	1.2	1.4	1.2	0.5	1.4	1.1	1.3
Alcohol drinker status: Never	0.9	1.1	2.4	-0.9	-1.2	-1.0	-0.9	-1.1	-1.1	-0.9	-1.0	-1.1	-1.1	-0.9	-0.9	-0.9	-0.9	-1.5	-1.1	-1.1	-1.0
Ulcerative Colitis	0.8	1.2	1.8	1.1	1.1	0.9	1.3	1.1	1.1	1.0	1.1	1.2	1.1	1.0	1.3	0.9	1.0	1.3	1.2	1.0	1.0
High blood pressure (mother)	0.8	1.1	1.8	-0.9	-1.1	-0.9	-1.2	-0.8	-1.0	-0.9	-1.2	-0.9	-1.1	-0.8	-1.2	-1.0	-0.9	-1.1	-1.3	-0.9	-1.0
Impedance of arm (right)	0.8	3.9	5.1	2.3	2.0	1.8	2.0	1.8	2.2	1.8	2.0	2.1	2.0	1.9	2.1	1.6	1.9	1.9	2.1	2.0	1.9
Medication: Lansoprazole	0.8	0.9	2.8	-1.3	-0.9	-0.7	-1.3	-0.7	-0.9	-0.7	-1.0	-0.8	-0.7	-0.6	-1.7	-0.5	-0.7	-0.7	-1.4	-0.8	-0.8
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	2.0	-1.2	-1.0	-1.1	-1.0	-0.7	-0.7	-1.3	-0.9	-1.0	-1.0	-1.0	-0.8	-1.4	-1.1	-0.3	-0.8	-0.9	-1.2
Age at last live birth	0.8	1.1	2.0	0.9	1.0	1.0	1.2	1.0	0.6	1.2	0.9	1.1	1.4	1.1	0.5	1.4	1.0	1.3	0.8	1.0	1.1
Leg fat-free mass (right)	0.8	4.2	7.4	1.8	1.6	2.0	2.2	2.1	1.4	2.2	2.2	1.7	2.0	2.1	2.7	2.4	2.1	0.9	2.1	2.1	2.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	1.9	-0.8	-1.1	-1.0	-0.8	-0.9	-1.1	-0.9	-1.0	-1.1	-1.0	-0.9	-0.6	-0.9	-0.8	-1.4	-1.0	-0.9	-0.9
Leg predicted mass (right)	0.8	4.2	7.3	1.9	1.7	2.1	2.2	2.1	1.4	2.2	2.2	1.8	2.0	2.1	2.7	2.4	2.1	0.9	2.1	2.1	2.3
Mother’s age at death	0.8	1.0	1.3	1.0	0.9	1.0	1.0	1.1	1.0	1.1	0.8	1.0	1.1	1.1	1.0	1.0	1.1	0.8	0.7	1.0	1.0
Tinnitus: Yes, now most or all of the time	0.8	0.9	1.5	0.4	0.9	1.2	0.5	1.2	1.0	0.9	0.8	0.9	1.0	1.1	1.0	1.1	1.0	0.9	0.5	1.1	1.1
Eye problems/disorders: Glaucoma	0.8	0.9	1.3	0.9	0.9	1.0	0.7	1.1	0.6	1.1	1.1	0.9	1.0	1.1	1.0	1.1	1.1	0.6	1.1	1.0	1.1
Leg fat mass (left)	0.8	3.3	5.1	-2.2	-2.0	-1.7	-1.8	-1.5	-2.1	-1.8	-1.7	-2.0	-1.8	-1.7	-1.8	-1.5	-1.8	-1.8	-1.8	-1.7	-1.8
Neuroticism (Nagel 2018)	0.7	1.6	3.5	-0.3	-1.4	-1.5	-0.5	-1.4	-1.5	-1.2	-1.2	-1.3	-1.2	-1.3	-0.8	-1.2	-1.3	-1.9	-1.1	-1.3	-1.2
Coronary Artery Disease (CAD)	0.7	0.9	1.2	-0.8	-1.0	-0.9	-1.0	-0.9	-0.8	-0.8	-1.0	-0.8	-1.1	-0.8	-1.0	-1.0	-0.9	-1.0	-1.1	-1.1	-1.0
Length of working week for main job	0.7	0.8	1.8	-1.1	-0.7	-0.7	-1.0	-0.8	-0.1	-1.1	-0.9	-0.8	-0.9	-0.8	-0.4	-1.3	-0.8	-0.5	-1.0	-0.8	-1.0
Exposure to tobacco smoke at home	0.7	0.8	2.2	0.9	0.6	0.8	1.3	0.7	0.5	0.8	1.0	0.6	0.9	0.7	1.5	0.9	0.8	-0.3	1.1	0.8	0.9
High blood pressure (siblings)	0.7	1.1	1.5	-0.8	-1.2	-1.2	-0.8	-1.0	-1.1	-1.1	-0.9	-1.1	-0.9	-1.1	-1.1	-1.1	-1.1	-0.6	-0.8	-1.1	-1.1
Neck or shoulder pain in last month	0.7	0.9	2.0	-0.9	-1.1	-1.0	-0.9	-0.8	-1.3	-0.8	-0.9	-1.1	-0.8	-0.9	-1.4	-0.7	-0.9	-0.7	-0.9	-0.9	-0.9
Ever had bowel cancer screening	0.7	0.8	1.8	-1.0	-1.1	-0.7	-1.0	-0.9	-1.0	-0.7	-1.0	-1.0	-0.5	-0.7	-1.3	-0.5	-0.7	-0.8	-1.2	-0.9	-0.7
Irritability	0.7	1.2	2.5	0.3	-1.1	-1.5	0.6	-1.4	-1.6	-0.9	-0.9	-1.2	-0.9	-1.4	-0.5	-0.8	-1.4	-1.3	-0.3	-1.2	-1.0
Blood Red Count	0.6	5.7	11.2	-2.2	-2.4	-2.5	-2.2	-2.4	-2.8	-2.2	-2.4	-2.5	-2.3	-2.5	-3.4	-1.9	-2.5	-1.6	-2.1	-2.4	-2.3
Medication for hormone replacement therapy	0.6	0.6	1.0	-0.8	-0.7	-0.8	-0.6	-0.9	-0.7	-0.9	-0.8	-0.8	-1.0	-0.8	-0.4	-0.9	-0.8	-1.0	-0.7	-0.9	-0.8
Leg fat-free mass (left)	0.6	3.2	5.9	1.6	1.4	1.8	1.9	1.9	1.2	1.9	2.0	1.5	1.7	1.8	2.4	2.1	1.9	0.7	1.9	1.9	2.0
Hand grip strength (right)	0.6	1.6	2.3	1.2	1.4	1.2	1.0	1.2	1.0	1.5	1.4	1.4	1.0	1.3	0.8	1.5	1.3	0.8	1.5	1.3	1.3
Age when periods started (menarche)	0.6	1.5	2.1	1.4	1.3	1.1	1.5	1.1	1.0	1.4	1.3	1.3	1.2	1.2	1.2	1.4	1.2	0.7	1.3	1.2	1.3
Leg predicted mass (left)	0.6	3.2	6.0	1.6	1.4	1.8	1.9	1.9	1.2	1.9	2.0	1.5	1.7	1.8	2.5	2.1	1.9	0.7	1.8	1.9	2.0
Nervous feelings	0.6	1.1	1.7	-0.2	-1.0	-1.2	-0.5	-1.3	-1.2	-0.9	-1.0	-1.0	-1.3	-1.2	-1.1	-0.9	-1.2	-1.3	-1.0	-1.1	-1.1
Had other major operations	0.6	0.7	1.5	-0.4	-0.9	-1.0	-0.2	-1.0	-1.2	-0.6	-0.9	-0.9	-0.9	-0.9	-0.8	-0.6	-0.9	-1.2	-0.7	-0.9	-0.8
Worrier / anxious feelings	0.6	1.1	2.0	-1.1	-0.9	-0.8	-1.4	-1.0	-0.7	-1.0	-1.0	-0.8	-1.1	-0.9	-1.3	-1.1	-0.9	-0.8	-1.4	-1.0	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.0	0.8	0.6	0.8	0.8	0.9	0.7	0.8	0.9	0.7	0.8	0.8	1.0	0.8	0.8	0.5	0.9	0.9	0.8
Had major operations	0.6	0.7	1.1	-1.1	-0.8	-0.7	-1.0	-0.7	-0.7	-0.9	-0.9	-0.9	-1.0	-0.8	-0.5	-0.9	-0.8	-0.8	-0.7	-0.7	-0.8
Illnesses of father: Heart disease	0.6	0.8	2.1	-0.6	-1.1	-0.9	-0.5	-0.9	-1.1	-0.8	-0.8	-1.0	-1.0	-0.9	-0.6	-0.7	-0.9	-1.5	-0.9	-0.9	-0.8
Financial situation satisfaction	0.6	0.8	1.0	0.8	0.9	0.9	0.8	1.0	0.8	0.9	1.0	0.9	0.9	0.9	1.0	0.9	0.9	0.7	0.7	0.9	0.9
Commuting to job workplace: Public transport	0.6	0.7	2.4	-0.4	-1.0	-1.0	0.3	-0.9	-1.6	-0.6	-0.9	-1.0	-0.5	-1.0	-0.5	-0.3	-0.9	-0.9	-0.3	-0.9	-0.7
Basal metabolic rate	0.6	3.1	5.7	1.5	1.3	1.7	2.0	1.9	0.8	2.1	1.9	1.4	1.8	1.8	2.1	2.4	1.8	0.7	1.8	1.9	2.0
Supplements: Calcium	0.6	0.7	1.1	-0.4	-1.0	-0.8	-0.4	-1.0	-0.8	-0.8	-1.0	-1.0	-0.8	-0.8	-0.3	-0.7	-0.8	-1.1	-1.1	-0.9	-0.7
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.1	-0.7	-1.0	-0.9	-0.8	-0.9	-0.7	-1.0	-0.9	-0.9	-0.9	-0.9	-0.7	-1.0	-0.9	-1.0	-1.0	-1.0	-1.0
Irritable Bowel Disease (IBD)	0.5	1.1	2.2	1.4	1.0	0.6	1.5	0.9	1.1	0.8	1.1	0.9	1.0	0.7	1.5	0.6	0.8	1.2	1.4	0.9	0.8
Waist Hip Ratio (WHR)	0.5	2.3	7.8	-1.8	-0.9	-0.9	-2.8	-1.2	-0.4	-1.6	-1.4	-0.9	-2.2	-1.1	-1.7	-1.9	-1.1	-1.1	-1.9	-1.3	-1.6
Fed-up feelings	0.5	1.0	2.5	-0.1	-1.1	-1.3	0.4	-1.2	-1.6	-0.8	-0.8	-1.1	-0.9	-1.2	-0.2	-0.7	-1.1	-1.3	-0.4	-1.1	-0.9
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.3	-1.1	-0.8	-0.8	-0.7	-0.4	-1.0	-0.8	-0.9	-0.8	-0.5	-0.7	-1.1	-0.7	-0.7	-0.0	-0.7	-0.6	-0.8
Waist circumference	0.5	1.8	3.2	-1.8	-1.5	-1.1	-1.6	-1.0	-1.5	-1.3	-1.2	-1.5	-1.6	-1.2	-1.3	-1.1	-1.2	-1.4	-1.5	-1.2	-1.3
Heart attack	0.5	0.6	1.0	-0.6	-0.9	-0.8	-0.7	-0.8	-0.6	-0.8	-0.7	-0.8	-0.8	-0.7	-0.5	-0.9	-0.7	-1.0	-0.9	-0.8	-0.8
Medication: Simvastatin	0.5	0.7	1.2	-0.8	-0.9	-0.9	-0.8	-0.8	-0.8	-0.8	-0.8	-0.9	-1.1	-0.8	-0.6	-0.8	-0.8	-1.1	-0.7	-0.8	-0.8
Neuroticism score	0.5	0.9	1.6	-0.2	-1.0	-1.1	-0.6	-1.1	-1.1	-0.9	-0.9	-1.0	-1.1	-1.0	-0.9	-0.9	-1.0	-1.3	-1.0	-1.1	-1.0
Arm fat mass (right)	0.5	2.0	3.8	-1.9	-1.6	-1.3	-1.5	-1.0	-1.6	-1.4	-1.3	-1.6	-1.5	-1.3	-1.3	-1.2	-1.3	-1.4	-1.5	-1.3	-1.4
Gout (self-reported)	0.5	0.6	2.2	-0.7	-0.3	-0.5	-1.5	-0.8	-0.1	-0.6	-0.8	-0.4	-1.0	-0.6	-1.4	-0.7	-0.6	-0.5	-1.0	-0.8	-0.7
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.2	-0.3	-0.5	-0.9	-0.9	-0.9	-0.6	-0.7	-0.8	-0.6	-1.1	-0.8	-1.1	-0.9	-0.9	-0.8	-0.6	-0.8	-0.8
Medication: Allopurinol	0.5	0.7	2.5	-0.9	-0.3	-0.5	-1.6	-0.8	0.0	-0.8	-0.8	-0.4	-1.0	-0.6	-1.4	-1.0	-0.7	-0.2	-1.0	-0.7	-0.8
Whole body fat mass	0.5	2.2	4.2	-2.0	-1.7	-1.3	-1.6	-1.1	-1.7	-1.4	-1.3	-1.6	-1.5	-1.3	-1.4	-1.2	-1.4	-1.5	-1.5	-1.3	-1.4
Family relationship satisfaction	0.5	0.6	1.0	0.8	1.0	0.8	0.5	0.7	1.0	0.7	1.0	0.9	0.8	0.8	0.5	0.7	0.7	1.0	0.7	0.7	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.5	-0.8	-0.6	-0.4	-1.2	-0.6	-0.5	-0.6	-0.8	-0.5	-0.9	-0.4	-0.9	-0.6	-0.5	-1.1	-1.1	-0.6	-0.6
Diabetes diagnosed by doctor	0.5	0.7	1.9	-1.1	-0.8	-0.6	-1.1	-0.8	-0.3	-0.9	-0.8	-0.8	-1.1	-0.6	-0.2	-1.0	-0.6	-1.4	-1.1	-0.8	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	3.0	0.8	0.8	0.6	0.7	1.0	1.1	0.4	0.8	0.7	0.7	0.6	1.3	0.2	0.7	1.7	1.1	0.8	0.6
Back pain experienced in last month	0.5	0.7	1.4	0.1	0.8	1.0	0.1	1.2	0.6	0.9	1.0	0.7	0.7	1.0	0.5	1.1	0.9	0.7	0.7	1.0	0.9
Ever taken oral contraceptive pill	0.5	0.6	2.0	1.2	0.7	0.3	1.4	0.5	0.4	0.7	0.7	0.6	0.8	0.4	0.9	0.7	0.5	0.7	1.1	0.6	0.7
Depressed Affect (Nagel 2018)	0.4	0.9	3.0	-0.6	-1.1	-0.8	-0.6	-0.9	-1.0	-0.8	-0.8	-0.9	-1.0	-0.8	-0.4	-0.8	-0.8	-1.7	-1.1	-0.9	-0.8
Intelligence (Savage-Jansen 2018)	0.4	1.3	4.3	1.5	0.8	0.8	2.1	0.8	0.4	1.4	1.0	0.9	1.4	0.9	1.1	1.5	1.0	0.4	1.4	0.9	1.2
Alzheimer’s Disease (in mother)	0.4	0.4	0.9	0.2	0.4	1.0	0.3	0.7	0.5	0.8	0.3	0.7	0.5	1.0	0.8	0.9	0.9	0.1	-0.1	0.7	0.8
Age at First Birth	0.4	0.7	1.3	-1.1	-0.7	-0.8	-0.9	-0.8	-0.4	-0.9	-0.7	-0.7	-0.6	-0.8	-1.1	-0.9	-0.8	0.2	-0.9	-0.9	-0.9
Body Mass Index (BMI) (2010)	0.4	0.6	1.3	0.7	0.9	0.7	0.7	0.7	0.8	0.7	0.8	0.8	0.8	0.7	0.5	0.6	0.7	1.2	0.8	0.7	0.6
Heel T-Score	0.4	3.5	7.5	2.0	1.3	1.4	2.6	1.6	0.5	2.0	1.7	1.3	2.7	1.4	1.3	2.5	1.5	2.1	2.2	1.6	2.0
BMI	0.4	2.5	4.4	-1.9	-1.5	-1.4	-2.1	-1.2	-1.4	-1.5	-1.4	-1.5	-1.9	-1.3	-1.9	-1.5	-1.4	-1.2	-1.8	-1.5	-1.6
Cardiovascular Disease	0.4	1.4	2.1	1.2	1.1	1.1	1.4	1.1	0.8	1.4	1.2	1.2	1.0	1.3	1.4	1.4	1.2	0.3	1.3	1.2	1.3
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.7	-1.2	-0.7	-0.5	-1.3	-0.6	-0.6	-0.6	-0.7	-0.6	-1.1	-0.5	-0.9	-0.6	-0.5	-1.2	-1.0	-0.7	-0.7
Chronotype (morning person)	0.4	1.0	1.8	-1.1	-1.1	-0.9	-1.0	-1.0	-1.3	-0.9	-1.0	-1.2	-0.9	-1.0	-1.3	-0.7	-1.0	-0.7	-1.0	-1.0	-0.9
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.3	1.1	0.6	0.7	0.9	0.7	0.7	0.8	0.8	0.7	0.7	0.8	1.1	0.8	0.8	0.4	0.6	0.7	0.8
Systolic blood pressure, automated reading	0.4	1.2	3.2	-0.7	-1.0	-0.8	-1.2	-1.0	-0.9	-0.7	-1.2	-0.8	-1.5	-0.8	-1.1	-0.8	-0.9	-1.8	-1.5	-0.9	-1.0
Trunk fat mass	0.4	1.7	3.5	-1.9	-1.5	-1.1	-1.4	-0.9	-1.6	-1.3	-1.1	-1.5	-1.4	-1.1	-1.2	-1.0	-1.2	-1.5	-1.3	-1.2	-1.2
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.4	1.0	0.8	0.6	0.6	0.5	0.2	1.0	0.8	0.7	0.7	0.6	-0.1	1.2	0.6	0.6	0.9	0.6	0.9
Alcohol intake versus 10 years previously	0.4	0.6	1.6	0.2	1.0	0.8	0.3	0.8	1.3	0.4	0.8	0.9	0.5	0.7	0.9	0.2	0.7	0.9	0.7	0.7	0.5
Birth weight of first child	0.4	0.7	1.3	0.9	0.7	0.8	0.8	0.8	0.4	1.0	0.8	0.7	0.7	0.8	0.8	1.2	0.9	0.4	0.8	0.8	1.0
Pulse wave reflection index	0.4	0.5	1.1	-1.0	-0.8	-0.3	-1.1	-0.4	-0.1	-0.8	-0.8	-0.6	-0.6	-0.4	-0.2	-1.0	-0.4	-0.6	-1.0	-0.5	-0.7
Forced vital capacity (FVC), Best measure	0.4	1.5	6.2	2.5	1.2	0.3	2.0	0.2	0.2	1.4	1.0	1.1	1.1	0.7	0.6	1.4	0.8	0.7	1.9	0.7	1.1
Age at first live birth	0.4	0.8	2.0	0.4	0.9	0.9	0.5	1.0	0.8	0.9	0.6	0.9	1.2	1.0	0.3	1.0	1.0	1.4	0.4	0.9	0.9
Arm predicted mass (right)	0.4	2.2	4.4	0.9	1.1	1.6	1.4	1.7	0.6	1.8	1.6	1.2	1.5	1.6	1.6	2.1	1.6	0.7	1.5	1.6	1.7
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.4	0.5	0.6	1.0	0.9	1.1	0.4	1.0	0.9	0.7	1.0	1.0	1.0	1.2	1.0	0.6	0.9	1.0	1.0
Loneliness, isolation	0.4	0.5	1.8	-0.5	-0.7	-0.6	-0.6	-0.7	-0.6	-0.6	-0.7	-0.7	-0.9	-0.6	-0.3	-0.6	-0.6	-1.4	-0.9	-0.7	-0.6
Arm fat mass (left)	0.4	1.7	3.2	-1.8	-1.4	-1.2	-1.4	-0.9	-1.4	-1.3	-1.2	-1.4	-1.4	-1.2	-1.2	-1.2	-1.2	-1.1	-1.3	-1.1	-1.3
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.8	-0.5	-0.5	-0.3	-1.4	-0.6	-0.2	-0.4	-0.5	-0.4	-1.0	-0.3	-1.2	-0.5	-0.4	-1.3	-1.2	-0.6	-0.5
Cholesterol lowering medication	0.4	0.5	1.4	-0.9	-0.8	-0.6	-0.7	-0.7	-0.7	-0.6	-0.7	-0.7	-0.9	-0.6	-0.6	-0.5	-0.6	-1.2	-0.8	-0.6	-0.7
Ulcerative Colitis (UC)	0.3	0.5	1.8	1.2	0.5	0.2	1.4	0.5	0.4	0.5	0.7	0.5	0.7	0.4	1.1	0.4	0.5	0.8	1.1	0.5	0.5
Neuroticism (2016)	0.3	0.4	0.9	-0.1	-0.6	-0.9	0.1	-0.9	-0.7	-0.7	-0.5	-0.7	-0.5	-1.0	-0.5	-0.6	-1.0	-0.1	-0.3	-0.8	-0.7
Respiratory disease	0.3	0.7	1.1	-0.5	-0.7	-1.0	-0.6	-1.0	-0.5	-0.9	-0.9	-0.7	-0.8	-0.9	-0.8	-1.0	-0.9	-0.1	-0.8	-0.9	-0.9
Diabetes (father)	0.3	0.3	1.4	0.3	0.4	0.2	0.8	0.5	0.3	0.3	0.6	0.3	1.0	0.3	0.4	0.4	0.4	1.2	0.9	0.5	0.4
Taking other prescription medications	0.3	0.4	1.1	0.2	0.5	0.7	0.4	0.8	0.6	0.7	0.7	0.6	0.4	0.8	1.1	0.8	0.7	-0.2	0.3	0.7	0.7
Serious illness, injury or assault to yourself	0.3	0.4	1.0	0.7	0.6	0.4	1.0	0.5	0.6	0.6	0.6	0.6	0.7	0.6	1.0	0.5	0.6	0.5	0.6	0.6	0.6
Chronic bronchitis/emphysema (father)	0.3	0.4	0.9	-1.0	-0.6	-0.3	-0.9	-0.4	-0.7	-0.5	-0.7	-0.6	-0.7	-0.4	-0.5	-0.4	-0.4	-0.8	-0.8	-0.4	-0.4
Past tobacco smoking	0.3	0.5	1.0	-0.8	-0.9	-0.8	-0.5	-0.7	-0.5	-0.9	-0.5	-1.0	-0.6	-0.8	-0.1	-1.0	-0.7	-0.6	-0.5	-0.8	-0.8
Qualifications: A levels/AS levels or equivalent	0.3	0.8	1.3	1.1	0.8	0.6	1.1	0.6	0.4	1.0	0.9	0.8	1.1	0.7	0.3	1.1	0.7	1.0	1.1	0.7	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	5.6	2.4	0.9	0.0	1.8	-0.1	-0.1	1.1	0.8	0.8	0.7	0.4	0.4	1.1	0.5	0.3	1.6	0.4	0.8
Loud music exposure frequency	0.3	0.3	0.9	1.0	0.8	0.5	0.5	0.4	0.7	0.6	0.4	0.7	0.4	0.5	0.4	0.4	0.5	0.7	0.3	0.5	0.5
Arm fat-free mass (right)	0.3	1.6	3.7	0.9	0.8	1.4	1.2	1.4	0.3	1.6	1.3	1.0	1.2	1.4	1.4	1.9	1.4	0.2	1.3	1.4	1.5
Medication: Seretide 50 evohaler	0.3	0.3	1.1	0.9	0.6	0.3	1.1	0.2	0.4	0.6	0.6	0.5	0.5	0.3	0.6	0.6	0.4	0.4	0.7	0.4	0.5
Medication for cholesterol	0.3	0.4	1.8	0.5	0.6	0.6	0.5	0.7	0.6	0.5	0.5	0.5	1.0	0.5	0.3	0.5	0.6	1.3	0.6	0.6	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.6	0.8	-0.5	-1.2	0.6	-1.3	-1.0	-0.4	-0.6	-0.6	-0.5	-1.0	-0.6	-0.5	-0.9	-0.7	0.1	-0.9	-0.6
Arm fat-free mass (left)	0.3	1.3	3.6	0.6	0.6	1.2	1.1	1.3	0.0	1.5	1.1	0.8	1.2	1.2	1.0	1.9	1.2	0.2	1.1	1.2	1.4
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.1	0.2	0.1	0.4	1.1	0.4	-0.1	0.5	0.6	0.1	1.0	0.3	0.8	0.8	0.4	0.3	0.5	0.4	0.6
Age started oral contraceptive pill	0.3	0.4	0.9	0.4	0.7	0.7	0.4	0.6	1.0	0.5	0.6	0.7	0.5	0.6	0.8	0.4	0.6	0.4	0.5	0.7	0.6
Pain experienced in last month	0.3	0.6	1.2	-0.1	-0.6	-0.9	-0.0	-1.1	-0.5	-0.8	-1.0	-0.6	-0.7	-0.9	-0.4	-1.0	-0.9	-0.5	-0.6	-0.9	-0.9
Impedance of whole body	0.3	1.4	2.0	1.1	1.3	1.1	0.9	1.2	1.4	1.1	1.1	1.3	1.3	1.2	0.9	0.9	1.2	1.3	1.2	1.2	1.1
Arm predicted mass (left)	0.3	1.3	3.6	0.7	0.7	1.2	1.2	1.3	0.0	1.5	1.2	0.8	1.2	1.2	1.1	1.9	1.2	0.2	1.1	1.2	1.4
Bipolar Disorder (2018)	0.2	0.4	0.7	-0.3	-0.3	-0.7	-0.8	-0.7	-0.2	-0.7	-0.5	-0.4	-0.7	-0.7	-0.8	-0.8	-0.7	0.1	-0.3	-0.6	-0.7
Schizophrenia vs Biploar Disorder	0.2	0.2	0.7	-0.6	-0.8	-0.4	-0.4	-0.2	-0.5	-0.4	-0.3	-0.6	-0.4	-0.3	-0.3	-0.4	-0.3	-0.8	-0.6	-0.4	-0.5
Bipolar Disorder (2011)	0.2	0.2	0.8	0.9	0.6	0.1	0.5	0.1	0.3	0.4	0.4	0.4	0.2	0.1	0.1	0.5	0.1	0.6	0.8	0.4	0.4
Mean Putamen Volume	0.2	0.2	0.7	0.0	-0.3	-0.7	-0.0	-0.8	-0.2	-0.6	-0.3	-0.4	-0.4	-0.7	-0.2	-0.7	-0.6	-0.2	-0.0	-0.6	-0.5
LDL Cholesterol	0.2	0.4	0.5	0.6	0.7	0.7	0.3	0.7	0.6	0.7	0.7	0.7	0.5	0.7	0.2	0.7	0.7	0.5	0.4	0.6	0.6
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.6	0.5	-0.4	-0.5	0.0	-0.6	-0.7	-0.4	-0.2	-0.7	-0.4	-0.8	-0.3	-0.0	-0.7	-0.7	-0.2	-0.3	-0.2
Vitamin and mineral supplements	0.2	0.3	0.9	0.1	0.3	0.6	0.6	0.7	0.2	0.6	0.6	0.4	0.6	0.6	1.0	0.7	0.6	-0.1	0.5	0.6	0.6
Townsend deprivation index at recruitment	0.2	0.3	0.7	0.0	-0.5	-0.8	0.0	-0.8	-0.4	-0.6	-0.5	-0.6	-0.5	-0.7	-0.4	-0.7	-0.7	-0.1	-0.3	-0.7	-0.6
Relative age voice broke	0.2	0.4	1.4	-0.2	-0.7	-0.7	0.1	-0.7	-1.2	-0.4	-0.7	-0.7	-0.5	-0.6	-0.3	-0.3	-0.6	-0.9	-0.3	-0.6	-0.5
Multivitamins +/- minerals	0.2	0.3	1.1	-0.3	-0.1	-0.3	-1.0	-0.5	-0.1	-0.4	-0.5	-0.2	-0.7	-0.3	-1.0	-0.5	-0.3	-0.2	-0.7	-0.4	-0.5
Hearing difficulty/problems with background noise	0.2	0.3	0.8	0.3	0.5	0.5	-0.0	0.5	0.3	0.6	0.5	0.4	0.6	0.5	-0.1	0.7	0.5	0.9	0.4	0.5	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	2.3	0.9	0.3	0.4	1.5	0.5	-0.1	0.8	0.6	0.4	1.2	0.5	0.7	1.0	0.5	0.7	0.8	0.6	0.7
Financial difficulties in last 2 years	0.2	0.2	0.4	-0.6	-0.5	-0.4	-0.4	-0.4	-0.2	-0.6	-0.3	-0.5	-0.5	-0.4	0.1	-0.6	-0.5	-0.6	-0.4	-0.4	-0.5
Hip circumference	0.2	1.0	2.4	0.4	0.5	1.0	1.2	1.3	0.1	1.2	1.1	0.5	1.1	1.0	1.3	1.5	1.0	0.4	1.0	1.1	1.2
Time employed in main current job	0.2	0.2	0.3	0.6	0.3	0.4	0.5	0.3	0.4	0.6	0.5	0.5	0.3	0.5	0.3	0.6	0.5	-0.4	0.3	0.4	0.5
Number of live births	0.2	0.3	1.1	-1.1	-0.3	-0.3	-0.8	-0.3	-0.1	-0.7	-0.7	-0.4	-0.7	-0.4	-0.5	-0.7	-0.5	-0.1	-0.8	-0.4	-0.6
Breastfed as a baby	0.2	0.2	0.7	0.8	0.3	0.2	0.7	0.2	0.1	0.5	0.4	0.3	0.4	0.3	0.5	0.5	0.3	-0.1	0.6	0.3	0.4
Qualifications: College or University degree	0.2	0.8	2.3	1.0	0.8	0.5	1.5	0.6	0.6	0.8	0.8	0.7	1.0	0.6	1.0	0.8	0.6	1.0	1.2	0.7	0.8
Medication for pain relief, constipation, heartburn	0.2	0.3	1.1	-0.2	-0.6	-0.5	-0.3	-0.6	-0.6	-0.4	-0.5	-0.6	-0.6	-0.5	-0.2	-0.4	-0.5	-1.0	-0.2	-0.6	-0.5
Alcohol intake frequency.	0.2	0.4	1.2	-0.3	-1.0	-0.7	0.6	-0.6	-1.1	-0.5	-0.6	-0.9	-0.3	-0.7	0.3	-0.3	-0.6	-0.9	-0.4	-0.6	-0.5
Number of full sisters	0.2	0.2	0.9	0.6	0.1	0.3	0.9	0.2	0.2	0.3	0.4	0.1	0.5	0.2	0.9	0.4	0.3	0.1	0.4	0.3	0.4
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.8	-0.2	-0.4	-0.4	-0.4	-0.6	-0.7	-0.3	-0.6	-0.4	-0.5	-0.5	-0.9	-0.3	-0.5	-0.5	-0.6	-0.5	-0.4
Supplements: Vitamin C	0.2	0.2	0.4	0.0	-0.4	-0.6	0.3	-0.5	-0.3	-0.6	-0.6	-0.4	0.0	-0.6	-0.5	-0.6	-0.6	0.5	-0.3	-0.5	-0.5
Mineral and other dietary supplements	0.2	0.3	1.3	0.1	0.2	0.0	1.2	0.3	-0.0	0.2	0.3	0.1	0.8	0.1	0.9	0.3	0.1	0.9	0.8	0.3	0.3
Osteoarthritis (self-reported)	0.2	0.2	0.5	0.0	0.4	0.6	0.2	0.7	0.3	0.6	0.4	0.4	0.3	0.6	0.4	0.7	0.6	0.0	0.3	0.7	0.6
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.2	-0.9	0.1	0.3	-1.1	0.4	0.3	-0.0	0.1	0.1	-0.0	0.2	-0.8	0.0	0.2	0.5	-0.1	0.2	0.0
Illnesses of father: High blood pressure	0.2	0.2	1.0	-0.4	-0.1	-0.3	-0.8	-0.4	-0.2	-0.2	-0.4	-0.1	-0.6	-0.2	-1.0	-0.2	-0.2	-0.2	-0.5	-0.3	-0.3
Risk taking	0.2	0.3	2.5	-0.1	0.5	0.5	-0.0	0.5	0.8	0.1	0.3	0.4	0.6	0.4	0.3	0.1	0.4	1.6	0.4	0.4	0.3
Unable to work because of sickness or disability	0.2	0.3	1.9	0.0	0.3	0.7	0.5	0.6	0.5	0.4	0.5	0.4	0.3	0.6	1.4	0.4	0.6	-0.3	0.2	0.5	0.5
Schizophrenia (2018)	0.1	0.2	0.8	0.9	0.4	-0.1	0.4	0.1	0.3	0.2	0.5	0.4	-0.1	0.1	0.4	0.0	0.2	0.1	0.9	0.2	0.1
Alzheimer’s Disease (in father)	0.1	0.1	0.4	0.2	0.4	0.5	-0.2	0.3	0.7	0.3	0.4	0.4	0.2	0.4	0.2	0.2	0.4	0.2	0.0	0.3	0.3
Crohns Disease (2017)	0.1	0.2	0.5	0.6	0.5	0.3	0.3	0.4	0.7	0.3	0.6	0.4	0.2	0.3	0.6	0.1	0.3	0.3	0.6	0.4	0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.5	0.3	0.2	0.4	0.4	0.3	0.1	0.6	0.4	0.3	0.5	0.4	0.1	0.7	0.4	-0.1	0.3	0.3	0.5
Crohns Disease (2012)	0.1	0.1	0.4	-0.2	0.0	-0.2	-0.5	-0.3	-0.0	-0.1	-0.1	-0.1	-0.7	-0.2	-0.4	-0.2	-0.2	-0.6	-0.1	-0.2	-0.2
Fasting Glucose	0.1	0.1	0.4	-0.6	-0.0	-0.2	-0.4	-0.3	0.0	-0.5	-0.1	-0.2	-0.2	-0.3	-0.3	-0.5	-0.3	0.2	-0.0	-0.3	-0.3
HDL Cholesterol	0.1	0.2	0.4	0.5	0.4	0.4	0.2	0.4	0.2	0.5	0.4	0.4	0.4	0.4	-0.1	0.6	0.4	0.1	0.4	0.5	0.5
Lupus	0.1	0.2	1.0	0.2	-0.5	-0.5	-0.0	-0.5	-0.5	-0.2	-0.0	-0.5	-0.4	-0.5	-0.2	-0.1	-0.4	-1.0	-0.2	-0.4	-0.3
Rheumatoid Arthritis	0.1	0.1	0.3	0.5	0.3	0.2	0.4	0.2	0.1	0.4	0.3	0.3	0.1	0.3	0.3	0.4	0.3	-0.3	0.3	0.3	0.3
Systolic Blood Pressure	0.1	0.5	1.5	1.2	0.6	0.6	1.1	0.5	0.5	0.8	0.4	0.7	0.5	0.7	1.0	0.7	0.7	-0.0	0.5	0.7	0.7
Smoking Status	0.1	0.3	1.1	-0.9	-0.5	-0.2	-0.7	-0.3	-0.4	-0.4	-0.6	-0.4	-0.4	-0.2	-0.5	-0.3	-0.3	-0.6	-1.0	-0.4	-0.4
Lung FVC	0.1	0.5	3.0	1.7	0.6	-0.8	0.9	-1.0	-0.5	0.2	-0.1	0.3	-0.1	-0.5	-0.8	0.1	-0.4	0.5	1.1	-0.4	-0.1
Neuroticism	0.1	0.2	0.5	0.4	-0.3	-0.5	0.1	-0.6	-0.4	-0.3	-0.3	-0.3	-0.5	-0.5	-0.3	-0.4	-0.5	-0.7	-0.2	-0.4	-0.4
Hand grip strength (left)	0.1	0.3	0.5	0.2	0.7	0.5	0.2	0.7	0.3	0.7	0.7	0.6	0.4	0.6	-0.1	0.7	0.5	0.7	0.7	0.6	0.5
Number of treatments/medications taken	0.1	0.3	0.9	-0.6	-0.4	-0.4	-0.6	-0.4	-0.4	-0.3	-0.5	-0.4	-0.8	-0.3	-0.4	-0.3	-0.4	-1.0	-0.8	-0.4	-0.4
Average weekly spirits intake	0.1	0.1	0.5	-0.4	-0.0	-0.1	-0.7	-0.2	0.2	-0.2	-0.0	-0.0	-0.5	-0.1	-0.7	-0.3	-0.1	-0.4	-0.4	-0.2	-0.3
Relative age of first facial hair	0.1	0.2	0.6	0.3	0.2	0.3	0.5	0.3	-0.3	0.6	0.3	0.3	0.5	0.5	0.3	0.8	0.5	0.1	0.4	0.3	0.5
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.6	0.4	0.0	-0.3	0.8	-0.1	-0.2	-0.0	0.1	-0.1	0.2	-0.2	0.5	0.1	-0.1	0.1	0.6	-0.0	0.0
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.2	-0.2	0.0	-0.3	0.1	-0.4	-0.2	-0.4	-0.2	-0.3	-0.4	-0.4	0.1	-0.4	-0.4	-0.4	0.0	-0.3	-0.3
Angina	0.1	0.1	0.4	0.2	-0.4	-0.5	0.1	-0.4	-0.3	-0.3	-0.3	-0.3	-0.5	-0.3	0.1	-0.4	-0.3	-0.6	-0.1	-0.3	-0.3
Pack years adult smoking proportion	0.1	0.2	0.4	0.2	0.3	0.5	0.3	0.4	0.7	0.3	0.4	0.4	0.3	0.5	0.7	0.3	0.4	-0.1	0.1	0.5	0.4
Current tobacco smoking	0.1	0.1	0.4	-0.6	0.1	0.5	-0.3	0.3	0.6	0.1	0.2	0.2	0.4	0.4	0.3	0.1	0.4	0.3	-0.3	0.2	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.5	0.7	0.1	-0.0	0.7	-0.1	0.2	0.1	0.1	0.1	0.3	-0.0	0.5	0.0	0.0	0.4	0.2	0.1	0.1
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.6	0.8	0.0	-0.2	0.7	-0.1	-0.4	0.2	0.3	-0.1	-0.0	-0.1	0.2	0.4	-0.1	-0.3	0.7	0.0	0.2
Stomach or abdominal pain in last month	0.1	0.2	0.8	-0.9	-0.1	-0.1	-0.8	0.1	-0.3	-0.2	-0.2	-0.2	-0.2	-0.1	-0.9	-0.1	-0.2	0.6	-0.4	-0.1	-0.2
Supplements: Glucosamine	0.1	0.2	0.6	-0.2	-0.1	-0.1	-0.8	-0.2	-0.2	-0.1	-0.3	-0.1	-0.7	-0.1	-0.5	-0.1	-0.1	-0.8	-0.4	-0.2	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.5	0.1	-0.4	-0.7	0.1	-0.5	-0.5	-0.6	-0.5	-0.5	-0.6	-0.7	0.0	-0.7	-0.6	-0.1	-0.2	-0.4	-0.6
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.6	-0.1	0.5	0.4	-0.2	0.3	0.5	0.2	0.1	0.4	0.4	0.4	-0.1	0.1	0.3	0.8	0.0	0.3	0.3
Qualifications: None of the above	0.1	0.3	0.8	-0.5	-0.9	-0.5	-0.1	-0.4	-0.6	-0.5	-0.7	-0.7	-0.3	-0.4	-0.2	-0.5	-0.4	-0.7	-0.9	-0.5	-0.5
Allergy	0.1	0.3	0.6	-0.1	0.5	0.7	0.1	0.7	0.7	0.4	0.3	0.5	0.8	0.7	0.4	0.5	0.6	0.7	0.1	0.6	0.5
Medication: Ramipril	0.1	0.2	0.3	0.2	-0.3	-0.6	-0.2	-0.5	-0.4	-0.4	-0.3	-0.4	-0.5	-0.5	-0.4	-0.5	-0.5	-0.3	-0.2	-0.5	-0.5
Father’s age at death	0.1	0.1	0.3	0.2	-0.4	-0.5	0.4	-0.5	-0.6	-0.2	-0.3	-0.3	0.1	-0.4	-0.2	-0.1	-0.3	-0.3	0.2	-0.4	-0.2
Hair/balding pattern: Pattern 3	0.1	0.2	0.8	0.8	0.3	0.0	0.9	0.1	-0.1	0.5	0.4	0.3	0.5	0.3	0.5	0.5	0.3	0.2	0.8	0.2	0.4
Asthma	0.1	0.1	0.3	-0.3	-0.1	-0.3	-0.5	-0.2	0.2	-0.4	-0.2	-0.1	-0.3	-0.2	-0.4	-0.5	-0.2	0.3	-0.4	-0.2	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.6	-0.5	0.2	0.3	-0.8	0.3	0.2	0.0	0.2	0.2	-0.1	0.2	-0.5	0.0	0.2	0.4	-0.1	0.2	0.0
Medication: Cholesterol lowering	0.1	0.1	0.6	-0.2	-0.3	-0.1	-0.3	-0.2	-0.2	-0.2	-0.3	-0.3	-0.6	-0.1	0.1	-0.2	-0.1	-0.8	-0.4	-0.2	-0.2
Lung cancer (father)	0.1	0.1	0.3	0.5	0.1	0.3	0.2	0.3	0.1	0.4	0.6	0.2	0.1	0.2	0.4	0.4	0.3	-0.3	0.5	0.3	0.3
Hair/balding pattern: Pattern 4	0.1	0.2	0.9	-0.1	-0.6	-0.2	-0.4	-0.4	-0.6	-0.1	-0.5	-0.4	-0.3	-0.3	-0.9	0.1	-0.3	-0.9	-0.7	-0.3	-0.2
Headache pain in last month	0.1	0.3	0.5	0.4	0.6	0.4	0.4	0.6	0.4	0.5	0.7	0.5	0.5	0.5	0.4	0.5	0.5	0.7	0.5	0.5	0.4
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.3	-0.3	-0.2	-0.4	-0.4	-0.3	-0.1	-0.4	-0.3	-0.3	-0.2	-0.4	-0.5	-0.5	-0.3	0.3	-0.2	-0.4	-0.4
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.4	-0.5	-0.2	-0.1	-0.3	-0.3	0.0	-0.4	-0.4	-0.3	-0.0	-0.3	-0.1	-0.3	-0.3	0.1	-0.6	-0.3	-0.2
Comparative body size at age 10	0.1	0.3	1.5	-0.1	-0.6	-0.6	0.0	-0.7	-1.2	-0.2	-0.7	-0.6	-0.1	-0.5	-0.7	0.1	-0.5	-0.4	-0.6	-0.6	-0.3
Worry too long after embarrassment	0.1	0.1	0.9	0.5	-0.0	0.2	0.1	-0.0	-0.3	0.4	-0.1	0.1	-0.2	0.2	-0.0	0.5	0.1	-0.9	-0.2	0.1	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.9	0.2	-0.3	-0.2	0.2	-0.4	-0.4	-0.1	-0.1	-0.3	-0.4	-0.2	0.4	-0.1	-0.2	-0.9	-0.2	-0.3	-0.1
Number of children fathered	0.1	0.2	0.6	0.4	0.4	0.3	0.5	0.1	0.3	0.3	0.4	0.3	0.2	0.2	0.8	0.3	0.3	0.4	0.7	0.3	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	0.4	-0.1	-0.2	-0.5	-0.3	-0.5	-0.5	-0.3	-0.4	-0.3	-0.4	-0.4	-0.6	-0.4	-0.4	-0.4	-0.3	-0.5	-0.4
Health satisfaction	0.1	0.1	0.3	-0.2	-0.1	-0.4	0.1	-0.4	-0.1	-0.4	-0.3	-0.3	-0.1	-0.5	-0.1	-0.5	-0.5	0.5	-0.1	-0.3	-0.4
Medication: Blood pressure	0.1	0.2	0.4	0.3	0.3	0.5	0.6	0.4	0.3	0.6	0.6	0.4	0.4	0.5	0.6	0.7	0.5	-0.2	0.4	0.5	0.6
Angina (self-reported)	0.1	0.1	0.3	0.2	-0.4	-0.4	0.1	-0.4	-0.3	-0.3	-0.3	-0.3	-0.5	-0.3	0.1	-0.4	-0.3	-0.6	-0.0	-0.3	-0.3
Medication: Ibuprofen	0.1	0.2	0.4	-0.1	0.4	0.5	-0.7	0.5	0.3	0.4	0.3	0.5	0.1	0.5	-0.5	0.4	0.5	0.4	-0.0	0.4	0.3
Medication: Omeprazole	0.1	0.2	0.3	0.4	0.4	0.3	0.5	0.4	0.0	0.5	0.2	0.3	0.6	0.3	0.2	0.6	0.3	0.6	0.4	0.4	0.5
Chest pain or discomfort	0.1	0.1	0.9	0.0	0.3	0.1	-0.3	0.2	0.4	0.1	0.1	0.4	0.3	0.2	-0.4	0.1	0.2	0.9	0.1	0.2	0.1
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.7	-0.7	-0.2	-0.1	-0.8	0.0	0.1	-0.4	-0.2	-0.2	-0.3	-0.2	-0.4	-0.5	-0.1	0.2	-0.5	-0.1	-0.4
Medication: Aspirin	0.1	0.1	0.4	-0.2	0.4	0.4	-0.4	0.3	0.6	0.3	0.2	0.5	0.2	0.4	-0.4	0.3	0.4	0.6	-0.2	0.3	0.3
Smoking status: Previous	0.1	0.1	0.5	0.7	0.5	0.2	0.3	0.2	-0.1	0.6	0.2	0.5	0.1	0.3	-0.2	0.6	0.3	0.2	0.3	0.3	0.4
Friendships satisfaction	0.1	0.1	0.5	0.1	-0.4	-0.4	0.4	-0.2	-0.7	-0.1	-0.3	-0.3	0.4	-0.3	-0.7	0.1	-0.3	0.2	-0.1	-0.2	-0.2
Qualifications: nursing, teaching	0.1	0.2	1.1	-1.0	0.0	0.0	-1.0	0.1	0.1	-0.4	-0.2	-0.1	-0.4	-0.1	-0.5	-0.4	-0.1	0.3	-0.2	-0.1	-0.3
Breast cancer (self-reported)	0.1	0.1	0.8	0.2	0.2	0.1	-0.3	-0.2	-0.3	0.4	-0.1	0.1	0.1	0.2	-0.9	0.7	0.1	-0.0	-0.4	-0.0	0.3
Asthma (self-reported)	0.1	0.2	0.5	-0.4	-0.0	-0.3	-0.7	-0.3	0.2	-0.4	-0.3	-0.1	-0.3	-0.2	-0.7	-0.6	-0.3	0.5	-0.4	-0.3	-0.4
Medication: Aspirin	0.1	0.2	0.4	-0.3	0.5	0.5	-0.3	0.4	0.5	0.4	0.3	0.5	0.3	0.5	-0.4	0.5	0.4	0.6	-0.1	0.4	0.4
Smoking status: Current	0.1	0.1	0.4	-0.7	0.1	0.5	-0.3	0.3	0.6	0.0	0.2	0.2	0.4	0.4	0.4	0.1	0.4	0.2	-0.4	0.2	0.2
Hearing aid user	0.1	0.1	0.7	-0.0	-0.3	0.1	0.4	0.2	0.1	0.0	-0.1	-0.1	0.2	0.1	0.8	-0.1	0.2	-0.4	-0.2	0.1	0.1
High cholesterol (Self-reported)	0.1	0.1	1.0	-0.2	-0.5	-0.2	0.1	-0.2	-0.7	0.0	-0.4	-0.4	-0.4	-0.1	0.1	0.2	-0.2	-1.0	-0.4	-0.2	-0.1
Ever smoked	0.1	0.2	0.4	0.2	0.6	0.5	-0.1	0.4	0.3	0.5	0.2	0.6	0.2	0.5	-0.4	0.5	0.4	0.4	0.1	0.4	0.4
Number of operations (self-reported)	0.1	0.1	0.5	0.0	-0.2	0.0	0.7	0.2	-0.5	0.2	0.1	-0.2	0.3	0.0	0.6	0.4	0.1	-0.4	0.4	0.2	0.2
Fractured/broken bones in last 5 years	0.1	0.1	0.8	0.2	-0.1	0.3	0.8	0.1	0.2	0.3	0.1	0.1	0.6	0.3	0.9	0.3	0.3	-0.2	-0.0	0.2	0.4
Vascular/heart problems diagnosed by doctor	0.1	0.4	0.9	-0.9	-0.5	-0.5	-0.5	-0.4	-0.4	-0.8	-0.7	-0.7	-0.2	-0.7	-0.6	-0.7	-0.6	0.7	-0.4	-0.5	-0.6
Basal cell carcinoma (self-reported)	0.1	0.1	0.5	-0.1	-0.4	-0.3	0.7	-0.2	-0.7	-0.1	-0.1	-0.5	0.3	-0.3	0.3	0.2	-0.3	0.0	0.0	-0.2	-0.0
Alcohol drinker status: Previous	0.1	0.1	0.3	0.2	-0.5	-0.0	0.5	0.1	-0.6	0.1	-0.3	-0.3	0.4	0.0	0.4	0.3	0.1	-0.2	-0.2	0.0	0.1
Pack years of smoking	0.1	0.1	0.5	0.1	0.1	0.3	0.2	0.2	0.5	0.2	0.3	0.2	0.2	0.3	0.7	0.1	0.3	-0.5	-0.0	0.3	0.2
Bipolar Disorder or Schizophrenia	0.0	0.1	0.3	0.5	0.1	-0.5	-0.2	-0.3	0.1	-0.2	0.1	0.0	-0.5	-0.3	-0.2	-0.5	-0.2	0.1	0.5	-0.2	-0.4
Depression (Nagel 2018)	0.0	0.1	0.2	0.4	-0.2	-0.3	0.4	-0.2	-0.2	-0.0	-0.2	-0.2	0.2	-0.2	0.4	-0.1	-0.2	0.0	-0.0	0.2	-0.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.1	0.3	0.5	-0.2	-0.6	0.4	-0.3	-0.3	-0.1	0.0	-0.2	-0.4	-0.4	0.0	-0.2	-0.3	-0.4	0.3	-0.2	-0.3
Blood Platelet Count	0.0	0.4	1.0	-0.4	-0.5	-0.5	-0.2	-0.6	-0.3	-0.8	-0.6	-0.5	-0.8	-0.6	0.3	-1.0	-0.6	-0.9	-0.5	-0.6	-0.7
Allergy or Eczema	0.0	0.1	0.5	0.7	0.1	-0.1	0.7	-0.0	-0.2	0.2	0.3	-0.0	0.0	-0.1	0.5	0.2	-0.0	-0.1	0.6	0.1	0.1
Hypothyroidism (self reported)	0.0	0.0	0.2	0.1	-0.1	-0.3	0.1	-0.2	-0.1	-0.3	-0.2	-0.1	-0.3	-0.3	0.1	-0.4	-0.2	0.0	0.0	-0.2	-0.3
Lung FEV1/FVC ratio	0.0	0.1	0.3	-0.0	0.2	0.5	0.1	0.4	0.4	0.4	0.5	0.3	0.3	0.4	0.3	0.4	0.4	-0.1	0.3	0.3	0.4
Hair Pigment	0.0	0.2	0.6	0.3	0.6	0.4	0.6	0.2	0.5	0.5	0.6	0.4	0.3	0.4	0.8	0.3	0.4	0.1	0.8	0.3	0.4
Tanning	0.0	0.1	0.5	-0.2	0.2	0.1	-0.3	0.0	-0.0	0.0	-0.1	0.1	0.4	0.1	-0.7	0.1	0.1	0.7	-0.2	-0.1	0.0
Sensitivity / hurt feelings	0.0	0.1	0.7	0.8	-0.1	-0.2	0.7	-0.2	-0.1	0.0	0.0	-0.0	0.2	-0.1	0.1	0.0	-0.1	-0.2	0.2	-0.1	-0.0
Impedance of leg (right)	0.0	0.2	0.9	0.3	0.4	0.2	0.2	0.3	0.3	0.4	0.2	0.5	0.6	0.3	-0.5	0.3	0.3	0.9	0.4	0.3	0.3
Maternal smoking around birth	0.0	0.0	0.1	0.2	0.1	-0.0	-0.1	-0.2	-0.1	0.1	-0.2	0.1	-0.2	0.1	-0.1	0.1	0.0	-0.3	-0.2	-0.1	0.0
Qualifications: CSEs or equivalent	0.0	0.0	0.1	0.2	0.3	0.2	-0.1	0.2	0.2	0.2	0.3	0.3	-0.2	0.2	0.1	0.2	0.2	-0.1	0.2	0.2	0.2
High blood pressure	0.0	0.1	0.7	0.5	0.3	0.2	0.1	0.1	0.2	0.5	0.3	0.4	-0.2	0.4	0.2	0.4	0.3	-0.8	0.1	0.2	0.3
Impedance of leg (left)	0.0	0.1	0.5	0.2	0.4	0.2	0.1	0.3	0.2	0.4	0.2	0.4	0.6	0.3	-0.6	0.4	0.3	0.7	0.3	0.3	0.3
Mouth/teeth dental problems	0.0	0.0	0.3	-0.1	0.1	0.3	-0.2	-0.1	0.0	0.2	-0.0	0.1	0.0	0.2	-0.1	0.3	0.1	-0.6	-0.2	0.0	0.2
Weight	0.0	0.1	0.6	-0.3	-0.4	0.0	0.3	0.3	-0.8	0.2	0.2	-0.3	0.1	0.1	0.3	0.6	0.0	-0.6	0.1	0.1	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.1	0.2	-0.4	-0.1	-0.1	-0.4	-0.3	-0.1	-0.3	-0.2	-0.2	-0.2	-0.3	-0.2	-0.3	-0.3	0.1	-0.5	-0.3	-0.2
Happiness	0.0	0.1	0.1	0.3	-0.0	-0.3	0.3	-0.4	0.1	-0.3	0.1	-0.2	-0.1	-0.3	0.1	-0.3	-0.3	-0.1	0.0	-0.3	-0.2
Medication: Paracetamol	0.0	0.1	0.2	0.1	-0.1	-0.4	0.1	-0.4	-0.2	-0.2	-0.2	-0.2	-0.0	-0.3	-0.3	-0.2	-0.3	0.2	-0.1	-0.3	-0.2
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.1	-0.1	-0.2	-0.2	0.2	-0.2	-0.2	-0.2	-0.2	-0.2	-0.2	-0.2	0.3	-0.2	-0.2	-0.4	-0.1	-0.2	-0.2
Medication: Amlodipine	0.0	0.0	0.1	0.3	0.2	0.1	0.2	0.0	-0.1	0.3	0.2	0.3	-0.1	0.2	0.0	0.3	0.2	-0.3	0.1	0.1	0.2
Hypertension (Self-reported)	0.0	0.1	0.2	0.3	0.3	0.3	0.0	0.2	0.2	0.4	0.3	0.4	-0.1	0.4	0.1	0.3	0.3	-0.5	0.0	0.2	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.1	0.3	-0.1	-0.1	-0.0	-0.2	0.1	-0.2	-0.1	0.0	-0.2	-0.1	0.2	-0.4	-0.0	-0.1	-0.0	-0.1	-0.2
Miserableness	0.0	0.0	0.1	0.0	0.0	0.0	0.1	-0.1	0.1	-0.0	0.3	-0.0	-0.0	-0.0	0.4	-0.0	0.0	-0.0	0.1	-0.1	0.0
Guilty feelings	0.0	0.0	0.2	-0.2	-0.1	-0.1	-0.1	-0.0	-0.2	-0.2	-0.2	-0.2	0.1	-0.1	-0.3	-0.2	-0.1	0.4	-0.2	-0.1	-0.2
Medication: Blood pressure	0.0	0.1	0.5	0.5	0.0	0.0	0.2	-0.1	-0.1	0.2	0.0	0.2	-0.3	0.1	0.3	0.2	0.1	-0.7	0.0	0.0	0.1
Medication: Paracetamol	0.0	0.1	0.2	0.4	-0.0	-0.4	0.5	-0.4	-0.3	0.1	-0.1	-0.1	0.2	-0.2	-0.4	0.2	-0.2	0.3	-0.0	-0.2	0.0
Medication: Lisinopril	0.0	0.0	0.2	-0.3	0.2	0.2	-0.2	0.3	0.2	0.1	0.1	0.2	0.2	0.2	-0.2	0.1	0.1	0.5	0.1	0.2	0.1
Diastolic blood pressure, automated reading	0.0	0.1	0.8	-0.3	-0.2	0.2	-0.6	0.0	-0.2	0.2	-0.3	-0.0	-0.5	0.2	-0.4	0.2	0.1	-0.9	-0.7	0.0	-0.0
Ever depressed for a whole week	0.0	0.0	0.3	0.1	-0.0	-0.1	0.1	0.0	-0.1	-0.1	-0.1	-0.0	0.2	-0.1	-0.3	0.0	-0.1	0.6	-0.1	0.0	-0.0
Myopia	0.0	0.1	0.4	0.2	-0.0	0.2	0.5	0.1	-0.2	0.2	0.0	0.1	0.1	0.1	0.6	0.2	0.2	-0.5	0.2	0.1	0.2
Medication: Omeprazole (e.g. Zanprol)	0.0	0.0	0.1	-0.0	-0.0	0.0	0.3	0.1	-0.1	-0.0	0.0	-0.1	0.2	-0.0	0.2	0.1	0.0	0.1	0.1	0.1	0.1

Hub : Genes

LLPH

Models

Trait associations