TWAS hub - LMO2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0359	0.014	0.0029	0.017	0.016	0.022	0.015	0.014	0.0013	0.0016	0.00028	0.002	0.0026
2	TCGA	Thyroid Carcinoma	0.0440	0.020	0.0053	0.020	0.023	0.019	NA	0.008	0.0041	0.0023	0.00490	NA	0.0540

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Blood Red Count	6.1	59.3	116.6	1.4	10.8
Noisy workplace	6.0	7.4	9.2	2.3	3.0
Birth weight of first child	5.2	9.5	11.8	-3.4	-2.7
Worrier / anxious feelings	3.9	7.3	9.2	2.4	3.0
Knee pain experienced in last month	3.9	6.1	10.2	-3.2	-1.4
Worry too long after embarrassment	3.6	6.1	9.5	1.6	3.1
Illnesses of siblings: Diabetes	3.3	4.1	6.6	-2.6	-1.2
Family relationship satisfaction	3.1	3.8	7.2	-2.7	-0.6
Fasting Glucose	2.9	3.4	4.0	-1.7	2.0
Ever taken oral contraceptive pill	2.9	3.2	4.6	-1.4	-2.1
Neuroticism score	2.8	5.8	7.8	1.9	2.8
Medication: Ventolin 100micrograms inhaler	2.8	3.6	7.0	-0.4	-2.6
Cholesterol lowering medication	2.8	4.1	7.7	-0.8	2.8
Sensitivity / hurt feelings	2.7	4.6	6.0	1.8	2.4
Supplements: Calcium	2.7	3.0	5.9	-2.4	-0.4
Neuroticism (2016)	2.5	3.6	5.8	2.4	1.2
Worry (Nagel 2018)	2.4	5.1	6.7	2.6	1.8
Major Depression (MDD)	2.4	3.0	5.6	0.6	2.4
Hypothyroidism (self reported)	2.4	5.5	7.4	-1.9	-2.7
Medication for hormone replacement therapy	2.4	2.7	4.4	2.1	1.0
Hypothyroidism/myxoedema (self-reported)	2.4	4.7	6.8	-1.6	-2.6
Commuting to job workplace: Walk	2.4	2.6	3.0	1.7	1.5
Impedance of leg (left)	2.3	11.4	17.5	2.3	4.2
Exposure to tobacco smoke outside home	2.3	3.0	5.9	2.4	0.4
Systolic blood pressure, automated reading	2.1	6.1	10.0	3.2	1.5
Ever depressed for a whole week	2.1	2.6	5.1	0.1	2.3
Bipolar Disorder (2018)	2.0	3.2	6.2	-0.5	2.5
Neuroticism (Nagel 2018)	2.0	4.7	5.0	2.1	2.2
Systolic Blood Pressure	2.0	9.9	18.7	4.3	1.1
Medication: Levothyroxine sodium	2.0	3.4	5.0	-1.4	-2.2
Falls in the last year	2.0	2.7	5.3	-0.3	-2.3
Tense / ‘highly strung’	2.0	3.3	4.7	2.2	1.4
Comparative body size at age 10	2.0	5.5	10.1	-3.2	-1.0
Age when periods started (menarche)	1.9	4.7	9.3	3.0	0.1
Hair/balding pattern: Pattern 2	1.9	2.4	3.6	1.1	1.9
Had menopause	1.9	2.3	3.6	1.0	1.9
Peak expiratory flow (PEF)	1.9	4.5	5.9	2.4	1.8
Suffer from ‘nerves’	1.9	3.0	3.0	1.7	1.7
Overall health rating	1.9	4.1	6.6	-2.6	-1.3
Miserableness	1.9	3.3	5.8	0.9	2.4
Schizophrenia vs Biploar Disorder	1.8	2.3	3.0	1.3	-1.7
Neuroticism	1.8	4.3	6.1	1.6	2.5
Impedance of leg (right)	1.8	8.5	11.7	2.3	3.4
Supplements: Glucosamine	1.7	2.2	4.1	-2.0	-0.5
Father’s age at death	1.7	2.3	4.3	0.5	2.1
Shortness of breath walking on level ground	1.7	2.0	2.1	-1.4	-1.4
Medication: Bendroflumethiazide	1.7	2.6	3.1	1.4	1.8
Body Mass Index (BMI) (2010)	1.6	2.2	3.6	-1.9	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.2	2.7	1.3	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	3.6	-0.3	-1.9
Friendships satisfaction	1.6	1.9	2.0	-1.4	1.4
Eye problems/disorders: Cataract	1.6	1.8	3.5	1.9	0.5
Fractured/broken bones in last 5 years	1.6	2.1	3.7	0.7	1.9
Heart disease (siblings)	1.6	1.9	2.6	-1.6	-1.1
HbA1C	1.5	1.6	1.7	-1.2	1.3
Exposure to tobacco smoke at home	1.5	1.7	3.5	0.1	-1.9
Financial situation satisfaction	1.5	1.8	2.5	-1.1	1.6
Respiratory disease	1.4	3.1	6.0	-0.5	-2.5
Illnesses of mother	1.4	1.8	3.1	0.7	-1.8
Medication: Paracetamol	1.4	2.4	4.5	-0.5	-2.1
Glaucoma (self-reported)	1.4	1.7	1.8	1.4	-1.2
Health satisfaction	1.4	1.8	3.0	-1.7	-0.7
Had major operations	1.4	1.6	2.2	-1.0	-1.5
Illness, injury, bereavement, stress in last 2 years	1.4	1.8	1.9	-1.3	-1.4
Osteoarthritis (self-reported)	1.4	1.8	3.6	-1.9	-0.0
Pain type(s) experienced in last month: Hip pain	1.4	1.8	2.2	-1.5	-1.2
Impedance of whole body	1.4	6.9	9.9	2.0	3.1
Type 2 Diabetes (T2D) (2018)	1.3	2.4	4.4	-2.1	-0.7
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.0	1.7	-0.2
Nervous feelings	1.3	2.5	3.5	1.9	1.2
Illnesses of siblings	1.3	1.8	1.9	1.3	1.4
Number of full brothers	1.3	1.6	1.7	-1.2	-1.3
Emphysema/chronic bronchitis	1.3	1.4	2.6	-0.5	-1.6
Heart disease (mother)	1.3	1.6	2.1	-1.0	1.4
Diastolic blood pressure, automated reading	1.3	4.1	5.3	2.3	1.7
Breast Cancer	1.2	2.9	5.8	-2.4	-0.1
BMI	1.2	6.8	10.7	-3.3	-1.7
Supplements: Zinc	1.2	1.3	1.6	-1.3	1.0
Stomach or abdominal pain in last month	1.2	1.5	2.3	1.5	-0.9
Number of live births	1.2	1.7	2.2	1.1	1.5
Eye problems/disorders: None of the above	1.2	1.4	2.8	-1.7	0.3
Risk taking	1.2	1.7	3.1	-0.6	-1.8
Intelligence (Savage-Jansen 2018)	1.1	3.4	6.8	-2.6	-0.2
Ever had hysterectomy (womb removed)	1.1	1.3	2.2	1.5	0.5
Length of working week for main job	1.1	1.2	2.1	1.4	0.6
Number of children fathered	1.1	1.3	2.6	1.6	0.1
Loneliness, isolation	1.1	1.5	2.2	1.5	0.9
Townsend deprivation index at recruitment	1.0	1.4	1.5	-1.2	-1.1
Relative age voice broke	1.0	1.6	3.0	1.7	0.5
Chronic bronchitis/emphysema (father)	1.0	1.1	2.2	1.5	0.3
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	1.7	1.3	-0.9
Supplements: Vitamin C	1.0	1.2	2.0	-1.4	0.6
Handedness (chirality/laterality): Left-handed	1.0	1.2	1.8	1.4	0.8
Mineral and other dietary supplements	1.0	1.3	2.2	1.5	-0.6
Illnesses of father: None of the above (group 1)	1.0	1.2	1.4	-1.2	-1.0
Depression (Nagel 2018)	0.9	1.4	1.7	1.0	1.3
Alzheimer’s Disease (in mother)	0.9	1.0	1.6	-1.2	0.7
Allergy or Eczema	0.9	2.2	3.9	0.8	-2.0
Frequency of depressed mood in last 2 weeks	0.9	1.3	2.4	0.4	1.6
Severe depression (siblings)	0.9	1.0	1.2	-1.1	0.8
Time employed in main current job	0.9	1.1	2.1	1.5	0.1
Hair/balding pattern: Pattern 3	0.9	1.3	2.6	-0.1	-1.6
Forced vital capacity (FVC), Best measure	0.9	3.3	6.6	2.6	0.2
Leg pain on walking	0.9	1.2	1.2	-1.1	1.1
Illnesses of father: Heart disease	0.9	1.2	1.4	-1.0	1.2
Number of self-reported non-cancer illnesses	0.9	1.6	3.1	-0.1	-1.8
Guilty feelings	0.9	1.4	2.5	0.6	1.6
Medication: Paracetamol	0.9	1.4	2.4	-0.7	-1.5
Average weekly beer plus cider intake	0.9	1.3	1.5	-1.0	-1.2
Triglycerides	0.8	1.3	2.4	-0.3	-1.6
Blood Eosinophil Count	0.8	6.2	10.2	-1.5	3.2
Diabetes (mother)	0.8	1.0	2.0	-1.4	0.1
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	1.6	0.4	1.3
Serious illness, injury or assault to yourself	0.8	0.9	1.5	0.6	1.2
Body mass index (BMI)	0.8	3.2	4.8	-2.2	-1.3
Arm fat percentage (right)	0.8	3.3	5.2	-2.3	-1.2
Alcohol intake frequency.	0.8	1.9	3.6	-1.9	-0.5
Number of full sisters	0.8	1.0	1.9	1.4	-0.4
Age at last live birth	0.8	1.1	2.1	1.5	-0.3
Medication: Aspirin	0.8	1.0	1.8	-0.4	1.4
Arm fat percentage (left)	0.8	3.1	5.0	-2.2	-1.1
Ever had bowel cancer screening	0.8	0.9	1.6	1.3	-0.4
Breast cancer (self-reported)	0.8	1.0	1.6	1.3	0.6
Wears glasses or contact lenses	0.8	0.9	1.5	0.5	1.2
Mother’s age at death	0.8	1.0	1.9	1.4	0.0
Verbal and Numeric Reasoning (VNR)	0.7	1.8	2.1	-1.4	1.2
Leg fat-free mass (left)	0.7	3.7	5.4	-1.4	-2.3
Maternal smoking around birth	0.7	1.0	1.1	-1.1	-0.9
Medication: Atenolol	0.7	0.9	1.8	1.3	-0.3
Leg predicted mass (left)	0.7	3.5	5.1	-1.4	-2.3
Medication: Ramipril	0.7	0.9	1.0	1.0	-0.9
Medication: Simvastatin	0.7	1.0	1.9	-1.4	0.4
Happiness	0.7	0.8	1.0	-0.8	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.1	4.1	2.0	-0.3
Loud music exposure frequency	0.7	0.8	1.4	-0.3	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	1.7	1.3	0.4
Medication: Ibuprofen	0.7	0.9	1.2	0.7	1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.1	0.6	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	1.7	0.2	-1.3
Unable to work because of sickness or disability	0.7	1.0	1.9	-1.4	-0.0
Pain experienced in last month	0.7	1.1	2.2	0.0	1.5
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.7	-0.4	-1.3
Depressed Affect (Nagel 2018)	0.6	1.3	1.4	1.1	1.2
Medication: Metformin	0.6	0.8	0.9	-0.9	-0.9
Fed-up feelings	0.6	1.1	1.4	0.8	1.2
Depression (self-reported)	0.6	0.7	1.1	-0.6	1.1
Medication: Seretide 50 evohaler	0.6	0.7	1.2	0.5	1.1
Leg fat-free mass (right)	0.6	3.1	4.2	-1.4	-2.1
Diabetes diagnosed by doctor	0.6	0.9	1.2	-1.1	-0.8
Medication for cholesterol	0.6	1.0	1.8	-0.4	-1.3
Medication: Aspirin	0.6	0.8	1.4	-0.4	1.2
Leg predicted mass (right)	0.6	3.1	4.4	-1.4	-2.1
Arm fat mass (left)	0.6	2.3	3.2	-1.8	-1.2
Hearing aid user	0.6	0.7	1.1	-1.0	0.5
Basal cell carcinoma (self-reported)	0.6	0.7	1.2	1.1	0.4
Alzheimer’s Disease (including proxy)	0.5	0.7	1.2	-1.1	-0.5
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.1	0.2	-1.1
Blood Platelet Count	0.5	5.8	8.2	1.9	2.9
Blood White Count	0.5	3.9	6.4	1.2	-2.5
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.2	-0.1	1.1
High blood pressure (mother)	0.5	0.7	1.5	1.2	0.1
Diabetes (self-reported)	0.5	0.8	1.4	-0.5	-1.2
Pulse rate	0.5	0.8	1.2	0.6	1.1
Asthma	0.5	0.9	1.7	0.4	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	0.8	0.6	0.9
Arm fat mass (right)	0.5	2.0	3.0	-1.7	-1.0
Qualifications: College or University degree	0.5	1.5	1.8	-1.4	1.0
Neck or shoulder pain in last month	0.5	0.7	1.3	-0.0	-1.1
Eye problems/disorders: Glaucoma	0.5	0.6	0.6	0.8	-0.8
Age started oral contraceptive pill	0.5	0.6	1.2	-1.1	0.1
Alcohol drinker status: Previous	0.5	0.6	1.2	-0.1	-1.1
Crohns Disease (2012)	0.4	0.7	1.4	1.2	0.0
Height	0.4	7.2	10.1	3.2	2.0
Lung FVC	0.4	2.0	2.4	1.5	1.3
Hand grip strength (left)	0.4	1.1	2.1	-0.5	-1.4
Relative age of first facial hair	0.4	0.8	1.0	1.0	-0.8
Angina	0.4	0.6	1.1	-1.1	0.1
Hand grip strength (right)	0.4	1.2	2.3	-0.2	-1.5
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.0	1.0	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	0.8	0.8	0.9
Allergy	0.4	0.9	1.0	-0.9	1.0
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	2.7	1.6	0.4
Mouth/teeth dental problems: Dentures	0.4	0.7	1.1	-0.5	-1.1
Lung cancer (father)	0.4	0.4	0.6	0.5	-0.8
Impedance of arm (left)	0.4	1.7	2.2	1.1	1.5
Gout (self-reported)	0.4	0.5	1.0	-0.2	1.0
Pulse wave peak to peak time	0.4	0.5	0.7	0.5	-0.8
Angina (self-reported)	0.4	0.5	0.9	-1.0	0.3
Smoking status: Previous	0.4	0.6	0.9	-1.0	0.5
Average weekly red wine intake	0.4	0.5	1.0	-0.4	1.0
Qualifications: nursing, teaching	0.4	0.6	1.2	-0.0	-1.1
Back pain experienced in last month	0.4	0.6	1.1	-1.1	0.1
Tinnitus: Yes, now most or all of the time	0.4	0.4	0.6	0.5	-0.8
Leg fat percentage (left)	0.4	1.3	2.6	-1.6	0.1
Number of operations (self-reported)	0.4	0.6	0.7	-0.8	-0.8
Vascular/heart problems diagnosed by doctor	0.4	1.1	1.9	-0.5	1.4
Bipolar Disorder or Schizophrenia	0.3	0.8	1.5	-0.4	1.2
Crohns Disease (2017)	0.3	0.6	0.8	0.9	0.7
Reaction Time	0.3	0.6	1.2	-0.0	-1.1
Smoking Status	0.3	0.7	1.1	-0.5	1.1
High blood pressure	0.3	0.9	1.5	0.5	-1.2
Sitting height	0.3	2.4	4.8	2.2	-0.3
Trunk fat mass	0.3	1.2	1.9	-1.4	-0.6
Waist circumference	0.3	1.1	1.8	-1.4	-0.6
Forced vital capacity (FVC)	0.3	1.3	2.6	1.6	0.0
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.7	-0.2	0.8
Financial difficulties in last 2 years	0.3	0.4	0.7	-0.8	-0.3
Mouth/teeth dental problems	0.3	0.4	0.7	-0.3	0.9
Weight	0.3	1.4	1.6	-1.3	-1.1
Impedance of arm (right)	0.3	1.5	2.3	0.8	1.5
Prospective memory result	0.3	0.3	0.6	-0.4	-0.7
Pulse wave Arterial Stiffness index	0.3	0.4	0.5	-0.5	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.6	0.8	0.7
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.7	0.9	-0.3
Headache pain in last month	0.3	0.5	0.8	0.9	-0.4
Body fat percentage	0.3	1.0	2.0	-1.4	-0.0
Leg fat percentage (right)	0.3	1.1	2.2	-1.5	-0.2
Wheeze or whistling in the chest in last year	0.3	0.6	1.1	-1.0	-0.1
Medication: Blood pressure	0.3	0.4	0.5	0.7	-0.6
Whole body fat mass	0.3	1.3	2.2	-1.5	-0.6
Leg fat mass (right)	0.3	1.2	2.2	-1.5	-0.4
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.5	0.5	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.5	0.7	0.5
Whole body fat-free mass	0.3	1.9	3.1	-0.9	-1.8
Mood swings	0.3	0.6	0.7	0.7	0.8
Long-standing illness, disability or infirmity	0.3	0.4	0.8	-0.1	-0.9
Asthma (self-reported)	0.3	0.6	1.1	-0.2	-1.1
Medication: Gliclazide	0.3	0.4	0.6	0.8	0.4
Whole body water mass	0.3	1.8	2.9	-0.8	-1.7
Commuting to job workplace: Public transport	0.3	0.4	0.7	-0.2	-0.8
Basal metabolic rate	0.3	1.8	2.6	-1.0	-1.6
Leg fat mass (left)	0.3	1.1	2.2	-1.5	-0.1
Alzheimer’s Disease (in father)	0.2	0.3	0.4	0.6	-0.4
Irritable Bowel Disease (IBD)	0.2	0.5	0.6	0.8	0.7
Ulcerative Colitis (UC)	0.2	0.3	0.6	0.8	0.4
Ovarian Cancer	0.2	0.3	0.4	0.5	-0.6
Age at First Birth	0.2	0.3	0.5	-0.7	-0.4
Coronary Artery Disease (CAD)	0.2	0.2	0.4	0.6	-0.2
LDL Cholesterol	0.2	0.4	0.7	-0.1	0.8
Primary Biliary Cirrhosis	0.2	0.3	0.5	-0.7	-0.3
Rheumatoid Arthritis	0.2	0.2	0.4	0.2	0.6
Schizophrenia (2014)	0.2	0.4	0.5	0.6	-0.7
Ulcerative Colitis	0.2	0.3	0.5	0.7	0.3
Waist Hip Ratio (WHR)	0.2	0.8	1.3	-0.4	1.2
Vitamin and mineral supplements	0.2	0.2	0.4	0.6	-0.2
Medication: Co-codamol	0.2	0.2	0.3	-0.3	0.6
Diabetes (father)	0.2	0.2	0.4	-0.0	0.6
Trunk fat percentage	0.2	0.9	1.7	-1.3	-0.2
Taking other prescription medications	0.2	0.3	0.3	-0.6	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.3	0.6	-0.3	-0.8
Multivitamins +/- minerals	0.2	0.3	0.4	0.5	0.6
Past tobacco smoking	0.2	0.3	0.4	0.6	-0.5
Hearing difficulty/problems with background noise	0.2	0.3	0.4	0.6	0.5
Had other major operations	0.2	0.2	0.4	-0.2	0.6
Pain all over the body in last month	0.2	0.3	0.3	0.4	0.6
Fluid intelligence score	0.2	0.4	0.7	-0.8	-0.5
Trunk fat-free mass	0.2	1.3	2.2	-0.6	-1.5
Hip circumference	0.2	0.9	1.0	-1.0	-0.9
Qualifications: A levels/AS levels or equivalent	0.2	0.4	0.6	0.4	0.8
Medication: Lansoprazole	0.2	0.2	0.3	-0.3	-0.6
Trunk predicted mass	0.2	1.3	2.2	-0.7	-1.5
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.4	-0.6	0.7
Medication: Amlodipine	0.2	0.3	0.5	0.7	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.4	0.0	-0.6
Age at first live birth	0.2	0.4	0.9	0.9	-0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.5	-0.1	-0.7
Mean time to correctly identify matches	0.2	0.3	0.4	0.5	-0.7
Chest pain or discomfort	0.2	0.3	0.7	0.2	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.3	0.5	-0.6
Hypertension (Self-reported)	0.2	0.4	0.7	0.4	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.5	-0.2	0.7
Average weekly champagne plus white wine intake	0.2	0.3	0.4	-0.6	-0.4
Medication: Blood pressure	0.2	0.4	0.7	-0.8	0.3
Irritability	0.2	0.4	0.7	0.8	0.4
Myopia	0.2	0.2	0.3	-0.6	0.4
Prostate Cancer	0.1	0.1	0.2	-0.4	-0.2
Bipolar Disorder (2011)	0.1	0.1	0.1	-0.4	0.0
Mean Putamen Volume	0.1	0.2	0.3	-0.6	-0.1
HDL Cholesterol	0.1	0.1	0.2	-0.2	0.4
Heel T-Score	0.1	0.7	0.8	0.7	-0.9
Lung FEV1/FVC ratio	0.1	0.5	1.0	1.0	0.2
Chronotype (morning person)	0.1	0.3	0.6	0.1	0.8
Number of treatments/medications taken	0.1	0.3	0.5	-0.7	-0.2
Average weekly spirits intake	0.1	0.1	0.2	-0.5	0.0
Hearing difficulty/problems: Yes	0.1	0.1	0.3	-0.5	-0.2
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.2	-0.4	0.2
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.1	0.2	-0.4
Average weekly fortified wine intake	0.1	0.2	0.3	-0.1	-0.5
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	-0.4	-0.3
Number of incorrect matches in round	0.1	0.2	0.3	-0.2	-0.6
Alcohol usually taken with meals	0.1	0.2	0.4	-0.6	-0.0
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.4	0.0	0.6
Alcohol intake versus 10 years previously	0.1	0.2	0.3	-0.2	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.3	0.3	-0.5
Medication: Cholesterol lowering	0.1	0.2	0.3	0.5	-0.5
Standing height	0.1	1.4	2.6	1.6	0.3
Breastfed as a baby	0.1	0.1	0.2	-0.4	0.2
Hair/balding pattern: Pattern 4	0.1	0.3	0.4	0.6	-0.4
Pulse wave reflection index	0.1	0.1	0.2	-0.4	-0.2
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.4	0.2	0.6
Blood clot in the leg (DVT)	0.1	0.2	0.3	-0.2	-0.6
Birth weight	0.1	0.3	0.6	-0.7	-0.1
Arm fat-free mass (right)	0.1	0.3	0.5	-0.2	-0.7
Medication: Allopurinol	0.1	0.1	0.2	0.1	0.5
Medication: Omeprazole	0.1	0.1	0.2	0.4	0.4
Pulse rate, automated reading	0.1	0.3	0.4	0.7	0.3
Osteoporosis (self-reported)	0.1	0.1	0.2	-0.4	-0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.2	-0.3	0.5
High cholesterol (Self-reported)	0.1	0.1	0.1	0.3	0.3
Medication: Atorvastatin	0.1	0.1	0.1	0.3	-0.2
Alcohol drinker status: Never	0.1	0.1	0.1	-0.1	-0.4
Ever smoked	0.1	0.2	0.2	-0.5	0.4
Arm fat-free mass (left)	0.1	0.5	0.9	-0.3	-0.9
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.3	0.5	0.1
Commuting to job workplace: Cycle	0.1	0.1	0.2	-0.3	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.2	0.5	0.3
Arm predicted mass (left)	0.1	0.3	0.6	-0.0	-0.8
Schizophrenia (2018)	0.0	0.1	0.2	-0.2	-0.4
Lupus	0.0	0.1	0.1	-0.1	-0.4
Cardiovascular Disease	0.0	0.2	0.3	0.6	-0.1
Hair Pigment	0.0	0.5	0.9	0.9	-0.3
Tanning	0.0	0.4	0.7	0.9	-0.4
Pack years adult smoking proportion	0.0	0.0	0.0	0.1	0.1
Current tobacco smoking	0.0	0.0	0.1	-0.0	0.2
Qualifications: CSEs or equivalent	0.0	0.0	0.1	0.3	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.1	-0.3	-0.2
Qualifications: None of the above	0.0	0.1	0.1	0.2	-0.4
Heart attack	0.0	0.0	0.0	0.0	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.1	0.1	-0.3	0.2
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.0	-0.1	0.2
High blood pressure (siblings)	0.0	0.1	0.1	-0.2	-0.3
Medication for pain relief, constipation, heartburn	0.0	0.0	0.0	-0.2	0.1
Migraine (self-reported)	0.0	0.0	0.1	0.0	-0.2
Arm predicted mass (right)	0.0	0.1	0.2	-0.1	-0.4
Comparative height size at age 10	0.0	0.0	0.1	-0.2	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.0	0.1	0.3	-0.0
Smoking status: Current	0.0	0.0	0.0	-0.2	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.0	0.0	0.1	0.0
Medication: Lisinopril	0.0	0.1	0.1	-0.0	0.3
Illnesses of father: High blood pressure	0.0	0.0	0.0	0.1	0.1
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.1	0.2	-0.1
Pack years of smoking	0.0	0.0	0.0	0.1	-0.0

Hub : Genes

LMO2

Models

Trait associations