Hub : Genes

LOC100130015

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2170 0.0460 5.9e-13 0.151 0.144 0.155 0.151 0.152 5.1e-18 3.6e-17 1.9e-18 5.6e-18 4.2e-18
2 TCGA Breast Invasive Carcinoma 0.0257 0.0112 4.6e-04 0.008 0.018 0.016 NA 0.010 6.6e-03 9.6e-05 2.5e-04 NA 3.2e-03
3 TCGA Head and Neck Squamous Cell Carcinoma 0.1089 0.0390 3.3e-08 0.058 0.070 0.084 NA 0.088 4.3e-07 2.5e-08 1.1e-09 NA 3.9e-10
4 TCGA Kidney Renal Clear Cell Carcinoma 0.0636 0.0247 1.2e-05 0.076 0.052 0.058 NA 0.069 5.8e-09 1.5e-06 4.1e-07 NA 3.5e-08
5 TCGA Lung Adenocarcinoma 0.0390 0.0201 2.5e-03 0.007 0.010 0.006 NA 0.003 4.2e-02 2.2e-02 5.9e-02 NA 1.2e-01
6 TCGA Lung Squamous Cell Carcinoma 0.0293 0.0160 4.5e-03 0.008 0.021 0.015 NA 0.006 4.1e-02 1.8e-03 6.1e-03 NA 5.7e-02
7 TCGA Prostate Adenocarcinoma 0.0817 0.0454 1.4e-03 0.018 0.017 0.016 NA 0.014 4.5e-03 6.6e-03 8.2e-03 NA 1.2e-02
8 TCGA Thyroid Carcinoma 0.0610 0.0250 3.0e-04 0.035 0.043 0.040 NA 0.038 2.2e-04 4.4e-05 8.4e-05 NA 1.2e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.2 1.9 7.4 -0.0 -1.7 -0.6 0.5 -1.4 -2.7 -1.5 -0.3
Bipolar Disorder or Schizophrenia 0.8 2.0 9.1 0.7 -1.8 -0.4 0.8 -1.2 -3.0 -1.0 -0.3
Depressed Affect (Nagel 2018) 0.3 0.7 2.0 -1.3 0.1 1.4 0.2 0.1 1.4 -0.0 -0.1
Depression (Nagel 2018) 0.5 0.7 2.1 -0.3 0.7 1.0 0.7 0.8 1.4 1.0 0.3
Intelligence (Savage-Jansen 2018) 1.4 4.2 10.8 -3.3 1.5 1.8 2.1 1.2 3.1 0.6 1.0
Neuroticism (Nagel 2018) 0.2 0.4 0.9 0.3 -0.7 -0.3 -0.8 -0.7 0.0 -0.5 -0.9
Schizophrenia (2018) 0.3 0.6 2.8 0.9 -0.9 -0.1 0.6 -0.4 -1.7 -0.1 -0.1
Schizophrenia vs Biploar Disorder 0.3 0.4 1.1 0.7 -0.5 0.2 -0.3 -0.8 -1.0 -0.0 0.8
Worry (Nagel 2018) 1.2 2.6 4.6 2.1 -1.3 -2.1 -1.6 -1.0 -1.2 -0.7 -2.0
Alzheimer’s Disease (in mother) 1.6 1.9 4.6 0.0 1.9 1.0 1.9 2.1 0.9 1.2 0.7
Alzheimer’s Disease (in father) 1.1 1.2 3.5 -1.1 1.2 0.8 1.9 1.0 0.3 1.1 0.6
Alzheimer’s Disease (including proxy) 2.2 3.2 6.9 -0.4 2.6 0.9 2.6 2.6 1.1 1.7 0.7
Crohns Disease (2017) 1.2 2.7 7.0 -2.6 -2.2 1.4 0.4 -2.5 -0.5 -1.1 -0.3
Irritable Bowel Disease (IBD) 0.3 0.6 2.3 -1.5 -0.6 1.1 0.5 -0.8 0.2 0.0 0.3
Ulcerative Colitis (UC) 0.1 0.3 0.7 0.1 0.6 0.3 0.1 0.7 0.6 0.8 0.3
Major Depression (MDD) 3.1 3.8 16.5 4.1 0.1 -2.2 -2.5 0.1 -1.4 0.3 -0.4
Reaction Time 0.4 0.9 2.5 -0.8 -1.2 0.3 -0.1 -1.6 -1.0 -0.9 -0.5
Verbal and Numeric Reasoning (VNR) 1.2 2.9 10.4 -1.8 1.6 1.4 0.9 1.4 3.2 1.2 1.0
Breast Cancer 0.2 0.5 1.6 0.1 -0.4 0.4 1.3 -0.3 -0.6 0.4 -1.1
Ovarian Cancer 2.1 2.7 5.4 -1.4 1.5 1.8 2.3 1.9 0.9 1.6 1.6
Prostate Cancer 1.0 1.4 5.3 0.8 -1.4 -0.6 -0.4 -1.4 -2.3 -0.4 0.4
Age at First Birth 0.9 1.2 5.0 -0.1 -0.6 -1.1 -2.2 -1.3 0.7 -0.8 -0.8
Bipolar Disorder (2011) 0.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 -1.7 0.2 0.6
Body Mass Index (BMI) (2010) 0.4 0.6 1.2 0.6 -0.7 -0.7 -1.0 -1.1 -0.6 -0.6 -0.3
Coronary Artery Disease (CAD) 0.6 0.7 2.7 -1.4 -0.3 1.0 1.6 -0.1 -0.4 0.2 0.0
Crohns Disease (2012) 1.8 3.0 7.4 -2.7 -2.1 0.9 0.4 -2.2 -0.2 -2.2 -1.1
Mean Putamen Volume 1.6 1.8 4.9 0.5 -2.0 -0.4 -1.2 -2.2 -0.6 -0.7 -1.6
Fasting Glucose 0.4 0.4 1.1 -0.6 0.4 1.0 -0.5 0.2 0.8 -0.3 1.0
HbA1C 0.2 0.2 0.8 -0.9 0.1 0.6 0.8 -0.0 0.3 -0.0 -0.2
HDL Cholesterol 0.1 0.2 0.4 -0.5 -0.5 -0.2 0.2 -0.5 -0.3 -0.5 -0.7
LDL Cholesterol 0.8 1.2 4.8 0.9 -1.0 -0.7 -0.6 -0.7 -2.2 -0.9 0.8
Lupus 0.2 0.4 1.3 1.1 -0.1 -0.7 -0.1 -0.0 -1.0 -0.2 -0.2
Neuroticism (2016) 1.0 1.5 3.5 0.8 -0.9 -1.1 -1.8 -0.8 0.1 -1.3 -1.9
Primary Biliary Cirrhosis 0.7 1.0 2.6 0.1 1.5 0.4 1.0 1.6 0.8 1.0 0.8
Rheumatoid Arthritis 0.2 0.3 1.1 0.2 -0.3 0.4 0.2 -0.3 -1.1 0.1 0.8
Schizophrenia (2014) 0.5 1.0 4.4 0.1 -0.7 0.6 1.4 -0.3 -2.1 -0.3 1.0
Triglycerides 0.7 1.1 3.5 -0.5 1.3 1.0 0.8 0.9 0.2 1.0 1.9
Type 2 Diabetes (T2D) (2012) 1.6 1.8 2.7 -1.2 1.5 1.2 1.6 1.6 1.2 0.8 1.5
Ulcerative Colitis 0.1 0.1 0.3 -0.3 -0.2 -0.0 -0.2 -0.2 0.2 -0.5 -0.3
Blood Eosinophil Count 0.1 1.0 2.0 -1.4 -1.4 0.6 0.9 -1.4 -0.6 -0.9 -0.4
Blood Platelet Count 0.1 1.6 4.2 -1.6 -1.4 1.2 -1.3 -2.0 0.8 -0.7 -0.3
Blood Red Count 0.6 5.7 14.4 3.1 2.4 -0.8 -0.0 3.8 2.1 3.2 -0.1
Blood White Count 0.4 3.0 8.4 0.0 2.1 0.8 2.3 2.9 1.1 1.9 0.6
Heel T-Score 0.3 2.2 10.8 0.8 0.0 -1.1 -3.3 0.6 1.6 -0.6 -1.2
BMI 0.3 1.9 8.1 1.4 0.9 1.2 -0.4 0.5 -0.7 1.4 2.9
Height 0.8 15.5 49.8 -7.1 2.4 3.8 1.8 3.1 5.9 -2.3 0.8
Waist Hip Ratio (WHR) 0.2 0.9 2.9 -0.5 0.1 1.7 1.7 0.7 -0.1 0.9 0.4
Systolic Blood Pressure 0.7 3.5 9.4 -0.4 -2.7 -0.7 -1.0 -3.1 -1.0 -1.7 -2.4
Smoking Status 0.6 1.5 4.7 -1.8 -0.0 1.7 2.2 0.4 -0.4 -0.3 0.7
Allergy or Eczema 0.2 0.6 1.3 -0.9 0.1 0.7 1.2 -0.0 -0.4 0.8 1.1
Cardiovascular Disease 0.1 0.3 0.9 1.0 -0.2 -0.7 -0.4 -0.3 0.1 0.6 0.0
Hypothyroidism (self reported) 0.6 1.3 2.3 -1.5 -1.1 0.8 1.2 -1.1 -1.4 -1.3 0.3
Respiratory disease 1.4 3.2 13.2 -3.6 -1.1 1.8 1.4 -1.1 0.5 -2.1 -0.4
Type 2 Diabetes (T2D) (2018) 0.2 0.5 1.0 0.8 1.0 0.1 -0.7 0.9 0.1 0.6 0.6
Lung FEV1/FVC ratio 2.1 10.9 19.3 -0.2 4.2 2.5 3.0 4.1 1.6 4.4 3.9
Lung FVC 0.4 2.2 6.8 0.9 1.6 -0.6 -0.1 2.6 2.0 1.7 -0.2
Neuroticism 0.4 0.9 1.5 0.8 -1.1 -0.9 -1.1 -1.2 -0.6 -0.6 -1.2
Chronotype (morning person) 0.4 0.8 2.3 -0.6 -1.1 -0.1 -0.3 -1.4 0.2 -0.7 -1.5
Hair Pigment 144.9 4131.5 9467.3 58.0 -68.9 -64.3 -72.2 -97.3 -55.0 -17.7 -52.8
Tanning 155.5 1898.2 4032.2 -52.4 34.3 51.8 63.5 49.9 26.0 8.4 36.2
Hand grip strength (left) 0.7 1.9 5.5 -1.3 -0.0 -0.7 -1.6 0.1 2.3 -1.4 -1.8
Number of treatments/medications taken 0.7 1.3 3.7 0.2 -1.6 -0.5 -0.0 -1.9 -1.7 -0.5 -0.4
Average weekly spirits intake 0.4 0.5 1.5 0.7 -0.5 -0.6 -1.2 -0.9 0.0 0.2 -0.8
Sensitivity / hurt feelings 0.7 1.2 1.8 1.3 -1.0 -0.8 -1.1 -1.1 -1.3 -0.7 -1.0
Frequency of depressed mood in last 2 weeks 1.0 1.4 2.8 -0.0 1.4 0.9 0.7 1.7 1.5 1.3 1.2
Hearing difficulty/problems: Yes 2.0 3.0 6.6 -2.6 1.2 2.4 2.1 0.6 1.1 0.4 2.1
Relative age of first facial hair 5.1 10.5 24.5 2.0 -4.1 -2.9 -3.1 -5.0 -2.7 -1.3 -3.5
Other serious medical condition/disability diagnosed by doctor 2.7 3.5 11.3 2.0 -1.9 -1.8 -0.7 -1.5 -3.4 -1.2 -1.3
Ever used hormone-replacement therapy (HRT) 0.1 0.1 0.4 -0.3 -0.1 0.1 0.6 -0.2 -0.3 0.5 0.5
Ever had hysterectomy (womb removed) 3.4 3.9 8.4 0.4 -2.9 -1.3 -1.4 -2.5 -2.2 -2.1 -1.9
Systolic blood pressure, automated reading 1.8 5.1 12.4 -0.3 -3.5 -1.1 -1.1 -3.5 -1.8 -2.3 -2.3
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 1.7 -0.1 1.0 -0.6 0.3 1.3 0.2 0.1 0.2
Angina 1.3 1.7 7.0 1.3 -1.2 -1.0 -0.1 -1.4 -2.6 -0.5 -0.2
Medication for hormone replacement therapy 0.4 0.4 1.0 -0.4 -0.5 -0.7 -1.0 -0.8 0.2 -0.7 -0.5
Vitamin and mineral supplements 0.3 0.4 0.8 -0.9 -0.9 -0.3 -0.5 -0.6 0.1 -0.7 -0.2
Supplements: Zinc 0.9 1.0 1.7 -0.7 1.2 1.0 1.3 1.0 0.9 1.2 0.5
Medication: Co-codamol 0.8 1.0 2.9 -1.7 1.1 0.7 1.1 0.6 1.1 -0.1 0.6
Medication: Metformin 0.6 0.9 2.2 1.4 0.7 -1.0 -1.5 0.8 0.6 0.4 -0.3
Diabetes (father) 1.3 1.6 2.5 1.2 -1.2 -1.1 -1.6 -0.8 -0.9 -1.5 -1.6
Diabetes (mother) 0.2 0.3 0.9 -0.9 0.3 0.8 0.4 0.3 0.2 -0.3 0.5
Severe depression (siblings) 0.6 0.7 2.2 0.1 -0.6 -0.9 -0.5 -0.6 -1.0 -1.5 -0.6
Pack years adult smoking proportion 0.3 0.5 1.1 0.5 0.9 0.4 -0.6 0.7 0.2 1.1 0.8
Impedance of leg (right) 0.3 1.4 4.6 -0.9 0.2 -0.3 -0.1 1.0 2.1 -1.0 -2.0
Leg fat-free mass (left) 0.5 2.6 7.3 -2.2 1.0 2.4 0.5 0.5 1.0 -0.3 2.7
Trunk fat percentage 2.7 10.7 25.8 -1.0 3.9 3.4 2.4 4.1 1.7 2.4 5.1
Hand grip strength (right) 0.7 2.0 7.0 -0.3 1.5 -0.8 -1.1 2.0 2.6 0.2 -0.9
Townsend deprivation index at recruitment 0.9 1.2 4.1 0.2 0.9 0.7 1.3 0.5 -1.0 1.3 2.0
Current tobacco smoking 0.5 0.9 1.5 -1.2 1.2 1.1 0.3 0.9 1.1 0.6 0.7
Average weekly fortified wine intake 3.2 3.7 8.4 0.3 -2.2 -1.7 -1.3 -2.3 -1.0 -2.3 -2.9
Maternal smoking around birth 1.2 1.7 3.6 -0.9 1.5 1.3 1.3 1.4 0.6 1.1 1.9
Fed-up feelings 0.8 1.5 3.1 0.2 1.6 1.2 0.8 1.4 0.7 1.8 1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.0 2.5 0.2 1.0 0.7 0.8 1.3 0.8 1.6 1.1
Relative age voice broke 0.4 0.6 2.2 0.6 -1.1 -0.1 -0.3 -1.5 -0.7 0.5 -0.0
Taking other prescription medications 0.5 0.8 1.9 -0.6 -1.4 0.2 0.6 -1.1 -1.4 -0.6 0.1
Age when periods started (menarche) 0.9 2.1 4.7 1.8 1.9 -0.8 -0.5 2.2 1.6 1.0 -0.6
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 0.9 -0.4 -0.8 0.1 -0.1 -1.0 -0.5 -0.7 -0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.7 4.8 0.5 -0.9 -1.5 -1.8 -0.6 -0.7 -2.2 -1.1
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.6 0.8 0.4 -0.4 -0.8 0.3 -0.1 0.1 0.6
Qualifications: CSEs or equivalent 1.6 2.1 3.8 -0.7 1.5 2.0 0.7 1.0 1.5 1.7 1.9
Serious illness, injury or assault to yourself 1.3 1.6 4.0 0.8 -1.3 -1.3 -1.1 -1.2 -1.1 -0.9 -2.0
High blood pressure 1.1 3.1 5.8 0.5 -2.4 -1.7 -1.3 -2.4 -1.8 -1.7 -1.4
Hayfever, allergic rhinitis or eczema 0.7 1.6 2.6 -0.6 1.4 1.1 1.3 1.2 0.8 1.6 1.6
Multivitamins +/- minerals 1.5 1.9 3.6 -0.7 1.9 1.6 1.7 1.4 1.1 1.1 1.2
Stomach or abdominal pain in last month 0.7 0.9 5.2 0.9 0.1 -0.2 0.3 0.0 -2.3 -0.2 1.1
Supplements: Glucosamine 0.0 0.0 0.0 0.0 0.2 -0.2 0.1 0.1 -0.1 0.2 0.0
Diverticular disease/diverticulitis (self-reported) 0.5 0.5 1.4 0.7 -0.7 -0.8 0.2 -0.2 -1.2 -0.9 -0.7
Medication: Atenolol 1.8 2.3 5.8 1.0 -2.4 -0.8 -0.3 -2.1 -2.2 -0.3 -1.2
Medication: Levothyroxine sodium 0.2 0.3 1.0 -0.9 -0.0 1.0 0.7 0.1 0.4 0.1 0.1
Sitting height 0.3 1.9 7.4 -2.7 0.2 0.9 0.0 0.3 1.7 -2.1 0.0
Chronic bronchitis/emphysema (father) 0.1 0.2 0.4 -0.5 0.1 0.5 0.3 0.3 0.6 0.3 0.2
High blood pressure (mother) 1.8 2.5 7.8 1.5 -1.0 -2.8 -2.0 -0.6 -0.5 -1.1 -1.8
Body mass index (BMI) 0.5 2.3 10.6 0.2 1.4 1.6 0.7 0.9 -0.6 1.3 3.2
Impedance of leg (left) 0.3 1.7 4.8 -0.5 0.5 -0.8 0.2 1.6 2.1 -0.7 -2.2
Leg predicted mass (left) 0.5 2.7 7.4 -2.2 1.1 2.4 0.6 0.7 1.1 -0.2 2.7
Trunk fat mass 1.9 8.1 20.7 -1.7 3.2 3.4 2.1 3.2 1.6 1.5 4.5
Waist circumference 1.1 4.1 12.5 -1.7 1.6 3.2 1.4 1.3 0.6 0.8 3.5
Number of incorrect matches in round 1.9 3.1 5.1 -2.3 -2.1 1.9 1.7 -2.2 -1.2 -1.5 0.1
Past tobacco smoking 1.0 1.9 6.4 2.1 0.8 -1.5 -2.5 0.3 0.7 0.7 -0.3
Alcohol usually taken with meals 0.8 1.3 2.6 1.2 -1.0 -1.2 -0.7 -1.2 -1.6 -1.3 -0.6
Nervous feelings 0.9 1.6 3.1 1.4 -1.1 -1.8 -1.3 -0.8 -1.1 -0.8 -1.6
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.6 3.5 1.7 1.5 0.3 0.3 1.6 0.1 1.9 1.2
Hearing difficulty/problems with background noise 1.4 2.2 6.6 -1.9 0.9 2.1 2.6 0.8 0.6 0.4 1.1
Hair/balding pattern: Pattern 2 0.4 0.6 1.4 0.2 -1.0 0.4 1.0 -0.9 -1.2 0.5 0.2
Had menopause 1.3 1.6 3.4 -0.2 -1.8 -0.3 0.6 -1.8 -1.6 -0.8 -1.5
Had other major operations 0.7 0.8 2.4 1.2 -0.7 -0.7 -1.6 -0.7 -0.5 -1.1 -0.1
Forced vital capacity (FVC) 1.2 4.5 19.1 -0.7 2.6 -0.3 -0.7 2.8 4.4 0.7 -0.7
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 2.5 -0.6 -0.1 -0.7 -0.8 0.1 0.1 -1.6 -0.2
Ever unenthusiastic/disinterested for a whole week 0.3 0.3 0.8 0.8 0.0 -0.0 0.6 0.3 -0.9 0.8 0.1
Qualifications: None of the above 0.6 1.2 5.4 1.3 -1.2 -0.4 0.3 -0.8 -2.3 -0.0 -0.1
Financial difficulties in last 2 years 0.4 0.5 1.0 0.9 0.8 0.3 0.3 0.8 -0.1 1.0 1.0
Mouth/teeth dental problems 0.2 0.3 1.3 0.2 0.4 0.2 0.1 0.8 1.1 0.5 -0.3
Heart attack 0.9 1.2 3.5 -0.5 -1.6 0.3 -0.7 -1.9 -1.2 -1.2 -0.4
Allergy 0.1 0.3 0.7 0.6 -0.6 -0.3 -0.6 -0.6 -0.3 0.2 -0.8
Pain all over the body in last month 0.3 0.3 0.7 0.8 -0.6 -0.2 -0.5 -0.2 -0.8 -0.1 0.7
Diabetes (self-reported) 0.3 0.5 0.9 0.6 1.0 -0.1 -0.6 0.8 0.3 0.9 0.7
Hayfever/allergic rhinitis (self-reported) 0.8 1.1 3.5 -0.5 1.1 1.1 1.2 0.6 0.0 0.9 1.9
Medication: Ramipril 0.6 0.8 1.9 -0.3 -1.4 -0.0 -0.3 -1.3 -1.1 -1.1 -0.5
Medication: Simvastatin 1.3 2.0 5.5 1.6 1.2 0.1 1.2 1.5 -0.7 2.4 1.5
Fluid intelligence score 1.4 2.9 6.9 -1.6 1.7 1.6 1.3 1.5 2.6 1.3 1.6
Illnesses of siblings 1.6 2.3 7.7 -0.4 1.7 1.3 -0.0 1.9 2.8 1.4 0.7
Neuroticism score 0.2 0.4 0.9 0.9 0.7 -0.5 -0.7 0.8 0.7 0.2 -0.1
Weight 0.8 3.8 10.0 -2.3 1.7 2.8 1.1 1.3 1.3 0.1 3.2
Impedance of arm (right) 0.6 3.0 4.5 -1.9 1.8 1.9 1.9 2.1 1.9 0.5 1.1
Arm fat percentage (right) 1.3 5.3 19.1 -0.6 2.3 2.8 1.8 1.9 0.1 1.7 4.4
Trunk fat-free mass 0.5 2.9 11.4 -3.4 -0.9 1.6 0.0 -1.5 0.7 -2.4 0.3
Hip circumference 0.7 3.2 7.5 -2.6 1.3 2.5 1.1 0.9 1.2 -0.5 2.7
Time employed in main current job 2.9 3.4 6.2 -0.3 -2.3 -1.0 -1.6 -2.5 -1.5 -2.4 -1.9
Alcohol intake versus 10 years previously 0.9 1.3 2.2 0.1 -1.2 -1.0 -1.2 -1.4 -1.5 -1.4 -0.4
Father’s age at death 0.3 0.4 1.3 0.8 -0.3 -1.0 0.5 0.3 -1.1 -0.3 -0.4
Worrier / anxious feelings 1.5 2.7 5.3 1.7 -0.9 -2.3 -2.1 -0.7 -1.0 -1.6 -2.0
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.1 0.5 -0.1 -0.3 0.0 0.3 -0.0 -0.7 -0.4 0.4
Falls in the last year 0.8 1.0 3.1 1.2 1.8 0.2 -0.1 1.1 0.2 1.0 1.2
Hair/balding pattern: Pattern 3 0.8 1.2 4.2 1.2 1.1 -0.9 -2.1 0.4 1.2 -0.4 -0.6
Number of live births 2.5 3.5 12.9 -2.5 1.2 1.9 3.6 1.7 0.5 0.5 0.7
Forced expiratory volume in 1-second (FEV1) 1.8 6.1 18.4 -0.5 3.6 0.4 0.1 3.6 4.3 2.0 0.6
Pulse rate 0.2 0.3 1.3 0.3 0.2 -0.1 -0.5 0.3 -0.1 0.5 1.1
Happiness 0.3 0.4 0.9 0.3 -0.7 -0.5 -0.4 -0.6 -0.9 -0.5 -1.0
Noisy workplace 1.4 1.8 3.5 0.2 -1.8 -1.1 -0.5 -1.7 -1.5 -1.0 -1.9
Qualifications: A levels/AS levels or equivalent 0.4 0.8 3.1 0.1 -0.3 -1.1 -1.8 -0.3 0.8 -0.8 -0.9
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 2.0 -0.8 -0.8 -0.3 -0.1 -1.0 -1.0 -1.4 -0.5
Mouth/teeth dental problems: Dentures 1.2 2.1 7.3 2.7 -0.2 -1.8 -1.4 -0.7 -1.8 0.5 0.0
Asthma 0.9 1.7 5.3 -2.3 -1.2 0.2 0.4 -1.0 0.0 -2.3 -0.9
Medication: Ibuprofen (e.g. Nurofen) 1.1 1.4 3.2 -1.8 -1.3 0.4 -0.6 -1.8 -0.2 -1.6 -0.3
Medication: Cholesterol lowering 0.9 1.4 5.2 2.3 0.8 -1.3 -1.0 1.1 -0.6 0.8 0.5
Depression (self-reported) 2.1 2.5 4.0 -1.3 1.4 1.8 1.6 1.3 1.7 2.0 1.5
Medication: Lansoprazole 1.8 2.1 6.8 2.6 -0.3 -2.0 -1.5 -0.4 -1.8 -0.1 0.2
Prospective memory result 0.9 1.0 2.3 -0.6 0.8 1.4 0.3 0.7 1.5 1.3 0.9
Lung cancer (father) 1.8 2.1 2.7 -1.4 1.3 1.3 1.5 1.5 1.6 1.6 1.4
Illnesses of mother 0.1 0.1 0.5 0.7 0.0 0.1 -0.5 0.1 0.1 0.3 -0.4
Forced expiratory volume in 1-second (FEV1), Best measure 1.6 5.0 16.3 -1.1 3.1 0.9 0.2 2.8 4.0 1.7 0.8
Pulse wave Arterial Stiffness index 0.4 0.4 1.4 -0.5 -0.7 -0.4 0.4 -0.8 -0.3 -0.5 -1.2
Impedance of arm (left) 1.5 6.8 16.6 -1.0 3.4 2.0 1.8 4.1 3.1 2.2 1.8
Arm fat mass (right) 0.8 3.4 13.1 -0.9 1.9 2.4 1.2 1.4 0.3 0.8 3.6
Trunk predicted mass 0.5 3.0 11.6 -3.4 -1.0 1.5 0.0 -1.6 0.7 -2.5 0.2
Standing height 0.9 8.5 31.5 -5.6 1.1 2.7 1.0 1.2 4.2 -2.7 0.2
Length of working week for main job 2.1 2.3 5.6 1.3 2.2 -0.1 -1.1 2.4 1.6 1.3 0.8
Exposure to tobacco smoke at home 0.3 0.3 0.7 -0.3 -0.7 -0.0 -0.3 -0.9 -0.8 -0.6 -0.4
Breastfed as a baby 0.3 0.4 1.3 1.1 0.2 0.2 -0.0 0.2 -0.5 0.7 0.9
Tense / ‘highly strung’ 0.3 0.5 1.5 1.2 -0.3 -1.0 -0.7 0.4 0.0 0.1 -1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.7 2.6 4.3 -0.4 1.5 1.7 2.1 1.9 0.6 2.0 1.8
Hair/balding pattern: Pattern 4 0.6 1.4 4.4 2.1 0.3 -1.5 -1.6 -0.2 0.3 0.8 -0.8
Birth weight of first child 0.5 1.0 2.7 -1.4 0.6 1.3 1.6 0.5 0.6 -0.2 0.5
Peak expiratory flow (PEF) 0.7 1.7 6.2 -0.4 1.9 -0.0 -0.5 1.6 2.5 0.7 -0.0
Pulse wave reflection index 0.9 1.2 4.4 -0.5 -1.1 -0.7 0.3 -1.1 -0.4 -1.2 -2.1
Ever highly irritable/argumentative for 2 days 0.3 0.4 1.5 -0.7 0.1 1.2 0.4 -0.3 -0.1 0.6 0.4
Loud music exposure frequency 1.4 1.5 5.6 -2.4 0.1 1.6 1.6 -0.3 0.2 -0.8 0.6
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 2.5 -1.2 0.6 0.0 -0.2 0.5 1.6 0.1 0.2
Mouth/teeth dental problems: Bleeding gums 1.0 1.3 6.0 -2.4 -0.3 1.3 0.5 -0.6 1.1 -0.7 -0.6
Blood clot in the leg (DVT) 1.0 1.3 3.8 1.1 1.9 0.4 -0.1 1.7 0.3 0.7 1.5
Medication: Paracetamol 0.5 0.8 1.8 -0.6 -1.3 0.0 0.4 -1.3 -0.8 -1.0 -0.7
Headache pain in last month 0.1 0.1 0.5 -0.2 -0.3 0.6 0.7 -0.1 -0.3 0.3 0.1
Medication for cholesterol, blood pressure or diabetes 0.9 1.5 6.0 -2.4 -0.5 1.5 1.2 -0.8 0.8 -0.6 -0.2
Glaucoma (self-reported) 1.0 1.1 1.8 -1.3 1.0 0.8 1.3 1.0 0.8 0.9 1.2
Gout (self-reported) 0.4 0.6 2.2 -0.4 1.2 0.4 -0.4 0.8 1.5 -0.3 -0.1
Hypothyroidism/myxoedema (self-reported) 0.4 0.8 2.5 -1.6 -0.5 1.2 1.1 -0.4 -0.2 -0.8 0.2
Medication: Amlodipine 0.7 0.9 2.0 -0.2 -1.3 -0.1 0.4 -1.4 -1.4 -1.1 -0.6
Medication: Ventolin 100micrograms inhaler 1.2 1.6 6.1 -2.5 -0.8 1.4 0.9 -0.8 0.2 -1.4 0.4
Birth weight 3.4 7.4 14.2 -2.8 2.5 3.5 3.8 2.5 1.4 2.0 2.5
Chronic bronchitis/emphysema (mother) 1.1 1.3 5.1 -2.3 -0.4 1.1 0.5 -0.6 0.7 -1.7 0.3
High blood pressure (siblings) 1.3 1.9 6.3 1.1 -1.0 -1.7 -0.3 -1.4 -2.5 -1.0 -0.7
Forced vital capacity (FVC), Best measure 1.2 4.2 18.1 -1.4 2.5 0.5 -0.3 2.5 4.3 0.7 -0.1
Body fat percentage 1.6 6.4 17.5 -0.6 3.0 2.8 1.8 3.0 1.0 1.9 4.2
Leg fat percentage (right) 0.3 0.9 3.7 -0.0 0.8 1.3 0.5 0.9 -0.1 0.5 1.9
Arm fat-free mass (right) 0.2 1.0 3.5 -1.9 0.1 1.0 -0.3 -0.2 0.9 -1.2 1.0
Exposure to tobacco smoke outside home 0.4 0.5 1.0 -0.8 0.8 0.7 0.7 1.0 0.3 0.5 0.7
Comparative body size at age 10 1.9 5.2 12.9 -0.1 2.0 2.2 2.7 1.4 -0.3 3.6 3.3
Number of full brothers 0.3 0.4 2.3 -0.4 -0.1 -0.5 -0.6 -0.2 -0.2 -1.5 -0.5
Worry too long after embarrassment 1.1 1.8 5.6 2.4 0.1 -1.6 -2.2 -0.6 -0.6 0.3 -0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.1 2.3 0.5 1.2 0.3 0.7 1.4 -0.5 1.4 1.5
Wheeze or whistling in the chest in last year 0.2 0.3 0.7 -0.8 0.4 0.8 0.7 0.1 -0.1 -0.6 -0.1
Number of children fathered 2.0 2.3 5.8 -2.4 -1.6 0.9 0.6 -1.7 -0.1 -1.9 -1.4
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.3 0.6 -0.0 -0.5 -0.4 -0.1 -0.8 -0.3 -0.8 -0.7
Age at first live birth 2.0 3.5 8.1 1.1 -1.4 -2.9 -2.2 -1.4 -1.1 -2.0 -2.1
Pulse wave peak to peak time 0.4 0.4 1.3 0.1 0.7 0.6 -0.5 0.7 0.6 0.1 1.1
Health satisfaction 0.5 0.7 3.3 0.6 0.2 0.2 0.4 -0.2 -1.8 0.4 1.2
Shortness of breath walking on level ground 0.6 0.7 2.7 0.3 1.3 0.5 0.4 0.8 -0.3 0.3 1.6
Qualifications: College or University degree 0.4 1.3 5.8 -1.3 1.2 0.1 0.0 1.2 2.4 -0.7 -0.4
Eye problems/disorders: None of the above 0.2 0.2 0.8 -0.0 -0.4 -0.1 -0.9 -0.3 0.3 -0.2 -0.7
Mouth/teeth dental problems: Loose teeth 0.5 0.6 2.2 -1.5 0.2 0.9 1.2 -0.2 -0.1 0.3 0.4
Emphysema/chronic bronchitis 1.0 1.2 3.7 0.4 -1.0 -0.6 -0.1 -0.9 -1.7 -1.9 -0.6
Medication for pain relief, constipation, heartburn 0.2 0.4 1.2 -0.1 1.0 0.1 -0.1 1.1 1.1 0.0 -0.2
Neck or shoulder pain in last month 1.1 1.6 3.2 1.8 1.7 -0.3 0.3 1.7 -0.3 1.4 1.2
Medication: Blood pressure 0.4 0.7 2.1 1.4 0.1 -1.2 -1.3 0.1 -0.8 -0.1 -0.4
Angina (self-reported) 1.0 1.3 5.3 1.5 -0.9 -1.1 -0.3 -1.0 -2.3 -0.2 -0.2
Migraine (self-reported) 0.2 0.2 0.7 0.4 0.2 -0.7 -0.6 0.2 -0.2 -0.8 -0.3
Medication: Ibuprofen 0.9 1.1 2.8 -1.7 -1.1 0.5 0.1 -1.4 -0.1 -1.5 -0.4
Medication: Allopurinol 1.4 1.9 5.2 -2.3 1.4 1.1 0.9 1.1 2.0 -0.5 0.5
Medication: Omeprazole 0.7 0.9 1.5 -1.2 -1.2 0.5 0.4 -1.2 -0.4 -1.2 -0.8
Medication: Seretide 50 evohaler 1.5 1.8 4.8 -2.2 0.2 2.0 1.8 0.5 0.8 0.1 1.0
Mean time to correctly identify matches 0.6 1.1 2.2 -1.4 -1.1 0.5 0.8 -1.5 -1.3 -0.8 -0.2
Heart disease (mother) 0.1 0.1 0.4 0.2 0.0 -0.4 0.2 0.2 -0.6 0.2 0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.9 2.3 5.1 1.4 1.8 -0.1 0.8 1.9 -0.1 2.3 1.8
Whole body fat mass 1.2 4.9 14.7 -1.2 2.4 2.8 1.4 2.3 1.0 1.0 3.8
Leg fat mass (right) 0.4 1.5 6.5 -0.5 1.1 1.7 0.4 1.1 0.3 0.3 2.5
Arm predicted mass (right) 0.2 0.8 2.7 -1.6 -0.1 0.8 -0.4 -0.4 0.6 -1.4 0.7
Pulse rate, automated reading 0.1 0.3 0.8 0.6 0.5 0.1 0.0 0.7 -0.1 0.8 0.9
Alcohol intake frequency. 1.1 2.5 7.6 1.9 -1.6 -1.2 -1.2 -1.5 -2.8 -0.6 -0.5
Comparative height size at age 10 1.2 6.8 20.9 -3.2 -1.9 -0.4 -2.3 -2.1 1.8 -4.6 -2.5
Number of full sisters 0.9 1.1 2.4 1.3 1.3 -0.0 -0.8 1.6 1.0 0.9 0.9
Suffer from ‘nerves’ 0.4 0.7 2.4 1.6 0.4 -0.4 -0.7 0.6 0.3 1.1 -0.4
Overall health rating 0.5 1.1 5.1 0.5 -0.3 -0.1 0.8 -0.5 -2.3 0.5 1.4
Chest pain or discomfort 0.3 0.4 2.4 0.6 0.0 -0.5 0.1 -0.1 -1.5 -0.5 0.5
Had major operations 1.5 1.8 5.4 -1.5 -1.5 -0.6 -0.8 -1.5 -0.7 -2.3 -0.9
Age at last live birth 0.3 0.4 1.0 0.0 -0.4 -1.0 -0.7 -0.6 -0.6 -0.9 0.0
Family relationship satisfaction 0.2 0.3 1.4 -0.6 0.2 0.4 -0.0 0.2 1.2 -0.2 -0.2
Leg pain on walking 1.0 1.2 3.3 0.7 1.5 0.2 0.2 1.5 -0.3 1.2 1.8
Qualifications: NVQ or HND or HNC or equivalent 1.5 1.9 3.8 -0.2 -1.5 -1.4 -1.6 -1.4 -0.6 -1.5 -2.0
Commuting to job workplace: Car/motor vehicle 0.5 0.5 2.0 -1.4 0.2 0.8 1.0 0.4 -0.2 0.0 0.5
Illness, injury, bereavement, stress in last 2 years 1.3 1.6 4.2 0.4 1.5 0.6 0.9 2.0 1.5 1.5 0.4
Medication: Aspirin 0.6 0.7 1.6 1.1 -0.9 -0.9 -0.7 -0.9 -1.3 0.3 0.2
Supplements: Vitamin C 1.5 1.7 5.4 2.3 -0.4 -1.6 -1.5 -0.4 -0.8 -0.1 -1.7
Knee pain experienced in last month 0.6 1.0 2.0 -0.7 1.4 0.7 1.4 1.0 0.1 0.4 1.3
Hypertension (Self-reported) 0.7 1.8 3.9 0.4 -1.9 -1.3 -1.2 -2.0 -1.3 -1.3 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.0 1.2 4.8 0.6 1.4 0.2 0.4 0.9 0.6 2.2 1.1
Illnesses of father: Heart disease 1.3 1.7 5.4 0.1 -1.6 -0.8 0.2 -1.8 -2.3 -1.1 -0.9
Illnesses of siblings: Diabetes 0.4 0.5 1.6 0.5 -0.2 -0.2 -1.3 -0.9 -0.6 -1.0 0.2
Smoking status: Previous 1.5 2.3 4.5 -1.2 -2.1 0.6 1.4 -1.7 -1.9 -1.8 -0.2
Forced expiratory volume in 1-second (FEV1), predicted 1.7 3.4 8.9 -2.8 1.6 2.2 0.4 1.3 3.0 -0.0 1.2
Whole body fat-free mass 0.4 2.2 8.9 -3.0 -0.3 1.8 0.2 -0.8 0.8 -1.7 1.1
Leg fat-free mass (right) 0.4 2.0 5.8 -1.9 1.0 2.0 0.5 0.6 1.0 -0.2 2.4
Arm fat percentage (left) 1.9 7.7 22.8 -0.1 3.2 2.9 1.9 2.9 0.7 2.6 4.8
Average weekly red wine intake 0.2 0.2 0.4 0.6 0.7 -0.6 0.5 0.5 -0.2 -0.2 -0.0
Handedness (chirality/laterality): Left-handed 2.5 3.0 7.6 -1.3 -2.5 -0.1 -1.0 -2.8 -0.7 -2.2 -1.3
Mood swings 0.1 0.2 0.5 -0.6 0.0 0.7 0.7 0.4 0.3 -0.4 0.2
Loneliness, isolation 0.7 1.0 2.2 0.6 1.4 0.3 -0.1 1.3 1.5 1.1 0.6
Long-standing illness, disability or infirmity 1.1 1.6 3.7 1.4 -1.2 -1.6 -0.8 -1.0 -1.9 -1.2 -0.7
Ever had bowel cancer screening 1.2 1.4 4.4 0.0 -1.8 -0.4 0.7 -1.6 -2.1 -0.5 -0.6
Diabetes diagnosed by doctor 0.2 0.4 0.9 0.5 0.9 -0.3 -0.8 0.8 0.2 0.4 0.3
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.4 4.4 -2.0 0.2 1.0 2.1 0.3 0.7 0.6 0.9
Friendships satisfaction 0.3 0.4 0.9 0.2 -0.9 -0.2 -0.4 -0.9 -0.4 -0.8 -0.7
Qualifications: nursing, teaching 0.3 0.4 1.3 -0.4 0.3 -0.3 -0.8 -0.1 1.1 -0.6 -0.8
Commuting to job workplace: Walk 0.8 0.8 1.4 0.2 0.8 1.0 0.7 1.1 1.0 1.2 0.9
Eye problems/disorders: Cataract 0.1 0.1 0.5 -0.3 -0.3 0.6 0.7 -0.1 0.1 0.2 0.2
Mouth/teeth dental problems: Mouth ulcers 0.7 1.2 3.8 -1.9 -0.3 1.0 1.8 -0.2 -0.6 -0.2 0.8
Medication for cholesterol 1.4 2.1 6.1 1.2 2.2 0.3 0.6 2.5 -0.1 1.4 1.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.9 3.7 1.2 -0.8 -0.2 0.3 -0.2 -1.9 0.2 0.9
Back pain experienced in last month 1.3 1.8 3.3 0.9 -1.1 -1.5 -0.9 -1.3 -1.8 -1.7 -1.2
Mineral and other dietary supplements 0.9 1.3 3.8 -1.5 0.6 1.2 0.6 1.0 2.0 0.6 0.6
Breast cancer (self-reported) 0.2 0.2 0.8 -0.5 -0.9 0.3 -0.3 -0.5 0.0 -0.5 -0.2
Asthma (self-reported) 0.8 1.7 6.7 -2.6 -1.0 0.6 0.6 -0.8 0.4 -2.0 -0.7
Osteoporosis (self-reported) 0.8 1.0 3.1 1.7 -0.5 -0.9 0.6 -0.0 -1.8 0.8 0.3
Osteoarthritis (self-reported) 0.6 0.8 3.2 1.8 0.4 -0.9 0.0 0.1 -1.4 -0.1 0.6
Medication: Aspirin 0.9 1.2 2.6 1.2 -1.2 -1.0 -0.9 -1.4 -1.6 -0.1 0.1
Medication: Gliclazide 1.1 1.2 2.1 0.6 -1.5 -0.4 -1.4 -1.4 -0.9 -1.2 -1.0
Illnesses of father: None of the above (group 1) 3.4 4.2 8.7 -0.4 2.5 2.0 1.3 2.3 1.7 2.3 2.9
Smoking status: Current 1.3 2.0 3.9 -2.0 1.6 1.6 1.0 1.4 1.6 0.9 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 1.0 0.9 1.0 -0.4 -0.8 1.0 1.0 0.7 0.6
Whole body water mass 0.4 2.2 8.5 -2.9 -0.2 1.9 0.2 -0.7 0.8 -1.6 1.3
Leg predicted mass (right) 0.4 2.0 5.6 -1.9 1.1 2.0 0.5 0.7 1.0 -0.1 2.4
Arm fat mass (left) 1.2 4.7 15.9 -0.8 2.5 2.6 1.3 2.1 0.7 1.4 4.0
Number of self-reported non-cancer illnesses 0.8 1.4 6.9 0.2 -1.4 -0.2 0.8 -1.1 -2.6 -0.6 0.6
Average weekly champagne plus white wine intake 0.4 0.6 1.2 -0.4 0.8 0.7 1.1 0.4 0.3 0.8 1.0
Miserableness 1.7 2.9 5.2 -2.2 1.4 2.3 1.3 1.4 2.2 0.9 1.4
Guilty feelings 0.9 1.4 2.9 -0.5 1.7 1.0 0.7 1.4 1.0 0.8 1.6
Wears glasses or contact lenses 0.1 0.1 0.3 0.4 0.2 -0.6 0.4 -0.2 -0.3 0.4 -0.2
Ever taken oral contraceptive pill 1.4 1.6 4.8 -1.4 1.3 1.4 0.3 1.1 2.2 0.8 0.7
Hearing aid user 1.7 1.9 4.4 0.0 -1.1 -2.1 -1.2 -1.3 -0.3 -1.9 -1.8
Mother’s age at death 1.5 1.8 4.3 2.1 -1.4 -1.5 -0.7 -0.9 -1.4 -0.6 -1.5
Financial situation satisfaction 1.5 1.8 6.0 -1.2 1.3 1.5 2.4 1.1 0.3 0.9 1.1
Tinnitus: Yes, now most or all of the time 0.6 0.7 1.1 -1.0 0.8 1.0 0.2 0.2 1.0 0.6 1.1
Commuting to job workplace: Public transport 0.4 0.4 1.1 -1.1 0.1 0.8 0.4 -0.2 1.0 0.2 0.4
Eye problems/disorders: Glaucoma 0.3 0.3 0.8 -0.4 0.5 -0.0 0.9 0.7 -0.0 0.7 0.6
Medication: Blood pressure 1.0 1.9 4.7 -1.3 -2.0 -0.6 -0.5 -2.2 -0.1 -1.8 -1.0
Pain type(s) experienced in last month: Hip pain 0.2 0.3 0.7 0.9 -0.2 -0.6 -0.3 -0.0 -0.3 0.6 -0.6
Supplements: Fish oil (including cod liver oil) 1.4 1.8 5.2 0.2 -1.1 -0.6 -0.2 -2.0 -2.3 -1.7 -0.4
High cholesterol (Self-reported) 0.3 0.5 1.0 0.7 0.4 0.3 0.6 0.8 -0.5 1.0 0.8
Medication: Bendroflumethiazide 0.3 0.5 2.2 -1.5 -0.5 0.5 -0.3 -0.7 0.4 -0.6 0.1
Medication: Paracetamol 0.6 0.9 1.9 0.2 -1.3 -0.6 0.4 -1.1 -1.4 -1.0 -0.8
Medication: Lisinopril 1.6 2.1 4.2 -1.2 -1.7 -0.9 -0.6 -2.0 -0.6 -2.0 -1.7
Medication: Atorvastatin 1.0 1.2 4.0 0.9 -0.5 -0.7 -2.0 -0.8 0.3 -1.4 -1.1
Illnesses of father: High blood pressure 1.6 2.0 3.8 1.6 -1.4 -1.9 -1.4 -0.9 -1.0 -0.7 -1.9
Alcohol drinker status: Never 0.5 0.5 1.7 1.3 -0.0 -1.1 -0.9 0.3 -0.5 -0.0 -0.3
Ever smoked 0.6 1.0 4.0 -1.6 -0.1 1.2 2.0 0.2 -0.1 -0.0 0.1
Basal metabolic rate 0.5 2.5 8.5 -2.9 0.4 2.2 0.4 -0.1 1.1 -1.2 1.9
Leg fat percentage (left) 0.3 1.0 3.3 0.2 1.0 1.0 0.7 1.2 -0.3 0.6 1.8
Arm fat-free mass (left) 0.4 2.0 5.7 -2.3 -0.9 1.0 -0.4 -1.5 0.0 -2.4 0.5
Number of operations (self-reported) 1.7 2.6 5.5 -0.5 -2.2 -0.7 -0.9 -2.3 -1.8 -2.2 -0.7
Average weekly beer plus cider intake 3.5 5.0 7.9 -2.7 1.9 2.8 2.0 1.9 2.5 1.8 2.0
Irritability 0.2 0.3 0.8 0.9 0.1 -0.9 -0.6 0.4 0.2 0.2 -0.3
Risk taking 1.7 2.4 5.0 -2.2 1.4 2.0 1.9 1.3 1.3 0.4 1.3
Ever had prostate specific antigen (PSA) test 1.6 1.8 2.7 1.6 -1.2 -1.6 -1.5 -1.2 -1.1 -0.4 -1.7
Fractured/broken bones in last 5 years 0.1 0.2 0.7 0.6 0.0 -0.3 -0.4 0.1 0.1 -0.0 -0.9
Age started oral contraceptive pill 3.0 3.8 6.6 2.4 -1.6 -2.6 -1.9 -1.6 -1.7 -1.6 -1.8
Diastolic blood pressure, automated reading 0.6 1.8 7.5 -2.7 -0.7 1.0 0.2 -0.6 2.0 -0.7 -0.5
Ever depressed for a whole week 0.7 0.9 2.4 0.1 0.8 1.0 0.7 1.0 0.6 1.5 1.3
Unable to work because of sickness or disability 0.4 0.5 1.3 1.1 0.4 -0.2 0.8 0.5 -0.9 0.9 0.4
Commuting to job workplace: Cycle 2.3 2.8 5.0 0.5 -1.4 -2.0 -2.2 -1.8 -0.1 -2.2 -1.8
Myopia 1.0 1.4 5.6 -2.4 -0.6 1.5 1.7 -0.2 0.1 0.0 -0.1
Vascular/heart problems diagnosed by doctor 0.8 2.3 4.9 -0.7 2.2 1.4 1.1 2.1 1.9 1.1 0.9
Cholesterol lowering medication 0.3 0.5 2.1 1.0 0.3 0.3 0.7 0.5 -0.0 1.4 0.2
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 2.1 -0.9 -1.4 0.3 0.3 -1.5 -0.8 -1.0 -0.7
Pain experienced in last month 0.5 0.8 2.2 -0.6 -0.9 -0.7 -0.7 -0.5 0.7 -1.2 -1.5
Supplements: Calcium 0.9 1.0 3.2 1.8 0.8 -0.7 0.0 1.3 -0.3 1.2 -0.2
Basal cell carcinoma (self-reported) 6.5 7.7 16.8 4.1 -1.6 -3.6 -4.1 -2.6 -1.5 -0.3 -1.8
Heart attack/myocardial infarction (self-reported) 0.8 1.1 3.0 -0.5 -1.5 0.4 -0.6 -1.7 -1.1 -1.2 -0.2
Deep venous thrombosis (DVT) (self-reported) 0.6 0.7 2.1 1.2 1.5 -0.0 -0.4 1.2 -0.1 0.1 0.9
Heart disease (siblings) 0.3 0.4 0.9 -0.5 -0.8 -0.2 0.6 -0.9 -0.8 -0.3 -0.5
Alcohol drinker status: Previous 1.5 1.7 3.3 -1.1 -1.8 0.5 1.3 -1.7 -1.8 -0.9 -0.4
Pack years of smoking 0.1 0.2 0.6 0.5 0.3 -0.1 -0.8 0.2 -0.2 0.5 0.3
Impedance of whole body 0.6 3.2 9.8 -0.8 2.2 0.8 1.2 3.1 2.7 0.9 0.1
Leg fat mass (left) 0.4 1.6 6.4 -0.4 1.2 1.6 0.5 1.2 0.3 0.4 2.5
Arm predicted mass (left) 0.4 2.1 6.4 -2.5 -0.9 0.9 -0.3 -1.4 0.0 -2.5 0.4