TWAS hub - LOC100272146

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0150	0.0101	0.00081	0.005	0.014	0.015	NA	0.011	2.9e-02	0.00049	0.00034	NA	0.00170
2	TCGA	Brain Lower Grade Glioma	0.0356	0.0246	0.00040	0.035	0.033	0.033	NA	0.032	7.4e-05	0.00011	0.00011	NA	0.00014

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
High cholesterol (Self-reported)	15.7	27.8	30.3	5.0	5.5
Medication: Simvastatin	11.7	17.1	23.8	3.2	4.9
Chest pain or discomfort	9.5	13.7	16.6	3.3	4.1
Medication: Atorvastatin	9.4	11.6	12.1	3.5	3.3
LDL Cholesterol	9.2	14.6	17.7	3.4	4.2
Diabetes (self-reported)	9.0	13.9	13.9	3.7	3.7
Cholesterol lowering medication	8.6	12.6	14.8	3.2	3.9
Medication for cholesterol, blood pressure or diabetes	8.5	14.0	14.4	-3.8	-3.7
Diabetes diagnosed by doctor	8.2	13.5	14.3	3.8	3.6
Breastfed as a baby	8.1	10.1	11.0	-3.0	-3.3
Cardiovascular Disease	8.0	26.3	27.0	5.1	5.2
Medication: Cholesterol lowering	8.0	12.4	14.1	3.3	3.8
Illnesses of father: Heart disease	7.6	10.6	11.6	3.1	3.4
Hearing difficulty/problems: Yes	6.8	10.4	14.6	2.5	3.8
Birth weight of first child	6.6	11.9	12.6	-3.3	-3.6
Angina	6.1	8.1	11.0	2.3	3.3
Eye problems/disorders: None of the above	5.9	6.8	8.8	-2.2	-3.0
Medication: Metformin	5.8	8.1	8.5	2.8	2.9
Type 2 Diabetes (T2D) (2018)	5.7	10.6	10.6	3.3	3.3
Risk taking	5.3	7.7	11.0	-2.1	-3.3
Angina (self-reported)	5.1	6.7	9.9	1.9	3.1
Eye problems/disorders: Diabetes related eye disease	5.0	5.5	7.2	1.9	2.7
Ever depressed for a whole week	5.0	6.2	7.6	2.8	2.2
Father’s age at death	4.6	6.2	6.2	-2.5	-2.5
Qualifications: NVQ or HND or HNC or equivalent	4.5	5.5	6.0	2.2	2.4
Medication for hormone replacement therapy	4.3	4.9	5.9	-1.9	-2.4
Medication: Paracetamol	4.3	7.2	7.8	2.8	2.6
Birth weight	4.3	9.4	11.2	-3.4	-2.8
Medication for pain relief, constipation, heartburn	4.3	7.3	8.5	-2.5	-2.9
Osteoarthritis (self-reported)	4.3	5.6	6.5	2.2	2.5
Ever had prostate specific antigen (PSA) test	4.2	4.9	5.6	-2.0	-2.4
Pack years adult smoking proportion	4.1	6.3	6.5	2.5	2.5
High blood pressure	4.1	11.3	13.5	3.0	3.7
Vascular/heart problems diagnosed by doctor	4.1	11.2	14.3	-2.9	-3.8
Medication: Lisinopril	3.9	5.0	7.1	2.7	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	3.7	4.9	6.8	-1.8	-2.6
Pulse wave Arterial Stiffness index	3.7	4.3	4.5	-2.1	-2.0
Number of self-reported non-cancer illnesses	3.7	6.5	6.8	2.6	2.5
Ever smoked	3.7	6.4	7.9	-2.2	-2.8
Pack years of smoking	3.7	5.5	5.6	2.4	2.3
Smoking Status	3.6	8.5	11.3	-2.4	-3.4
Depression (Nagel 2018)	3.5	5.2	6.5	-2.0	-2.5
Hypertension (Self-reported)	3.5	9.7	12.1	2.7	3.5
Medication: Aspirin	3.4	4.5	6.4	1.6	2.5
Alcohol drinker status: Never	3.4	4.1	5.4	-2.3	-1.7
Alcohol usually taken with meals	3.3	5.3	5.9	-2.4	-2.2
Medication: Gliclazide	3.3	3.8	5.2	1.5	2.3
Medication: Paracetamol	3.3	5.0	5.8	2.4	2.1
Pulse wave peak to peak time	3.2	3.7	4.4	2.1	1.8
Past tobacco smoking	3.1	5.7	6.5	2.2	2.5
Worry too long after embarrassment	3.1	5.3	6.6	2.6	2.0
Medication: Aspirin	3.1	4.1	5.0	1.8	2.2
Height	3.0	57.8	65.8	-7.1	-8.1
Primary Biliary Cirrhosis	2.8	4.0	6.4	1.3	2.5
Heart attack	2.8	3.5	5.6	1.2	2.4
Irritability	2.8	4.7	6.8	2.6	1.6
Heart attack/myocardial infarction (self-reported)	2.8	3.6	5.5	1.3	2.3
Mouth/teeth dental problems	2.7	4.2	4.3	-2.1	-2.0
Ever highly irritable/argumentative for 2 days	2.7	3.2	4.6	2.1	1.4
Number of incorrect matches in round	2.6	4.4	6.2	-1.6	-2.5
Standing height	2.6	26.2	31.9	-4.5	-5.7
Fractured/broken bones in last 5 years	2.6	3.4	5.0	-2.2	-1.3
Systolic Blood Pressure	2.4	12.1	16.2	4.0	2.8
Mouth/teeth dental problems: Dentures	2.4	4.0	5.7	1.5	2.4
Prospective memory result	2.4	2.9	3.0	-1.7	-1.7
Medication: Blood pressure	2.4	4.2	5.4	1.8	2.3
Age when periods started (menarche)	2.3	5.6	8.9	-1.5	-3.0
Medication: Atenolol	2.3	2.9	3.9	1.4	2.0
Time employed in main current job	2.3	2.6	4.0	-1.1	-2.0
Glaucoma (self-reported)	2.3	2.7	4.5	1.0	2.1
Overall health rating	2.3	5.0	5.3	2.2	2.3
Friendships satisfaction	2.3	2.9	3.3	1.5	1.8
Lung FEV1/FVC ratio	2.2	11.1	15.2	2.7	3.9
Diabetes (father)	2.2	2.7	3.2	1.8	1.5
Impedance of arm (right)	2.2	10.4	16.3	-2.1	-4.0
Trunk fat percentage	2.1	8.2	9.4	-3.1	-2.6
Diverticular disease/diverticulitis (self-reported)	2.1	2.5	3.8	-1.1	-2.0
Trunk fat mass	2.1	9.0	10.7	-3.3	-2.7
Medication: Blood pressure	2.1	4.0	6.2	1.3	2.5
Ever used hormone-replacement therapy (HRT)	2.0	2.6	3.3	-1.4	-1.8
Smoking status: Previous	2.0	2.9	3.8	-1.4	-2.0
Eye problems/disorders: Glaucoma	2.0	2.3	3.6	1.0	1.9
Hip circumference	1.9	8.2	12.4	-3.5	-2.0
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	3.6	-1.6	-1.9
Hearing difficulty/problems with background noise	1.8	2.8	3.4	1.5	1.8
Health satisfaction	1.8	2.4	4.4	0.6	2.1
Neck or shoulder pain in last month	1.8	2.5	3.2	1.8	1.4
Verbal and Numeric Reasoning (VNR)	1.7	4.1	6.8	1.2	2.6
HDL Cholesterol	1.7	2.9	3.6	1.9	1.4
Medication: Co-codamol	1.7	2.0	2.8	1.1	1.7
Fluid intelligence score	1.7	3.5	3.7	1.8	1.9
Impedance of arm (left)	1.7	7.9	12.5	-1.8	-3.5
Mouth/teeth dental problems: Bleeding gums	1.7	2.1	2.2	1.4	1.5
Smoking status: Current	1.7	2.7	2.7	-1.6	-1.6
Lupus	1.6	2.4	2.4	1.6	1.6
Chronotype (morning person)	1.6	3.7	5.3	-2.3	-1.5
Frequency of tenseness / restlessness in last 2 weeks	1.6	2.5	3.4	-1.3	-1.8
Forced vital capacity (FVC)	1.6	6.1	8.9	-1.8	-3.0
Forced vital capacity (FVC), Best measure	1.6	6.0	8.4	-1.9	-2.9
Alzheimer’s Disease (including proxy)	1.5	2.2	2.4	-1.5	-1.4
Hayfever, allergic rhinitis or eczema	1.5	3.2	3.8	-1.9	-1.6
Happiness	1.5	1.9	2.3	1.5	1.2
Worry (Nagel 2018)	1.4	3.0	4.1	-1.4	-2.0
Medication: Ramipril	1.4	1.8	3.5	0.1	1.9
Qualifications: A levels/AS levels or equivalent	1.4	3.1	4.4	1.3	2.1
Loneliness, isolation	1.4	1.9	2.2	1.5	1.3
Medication: Bendroflumethiazide	1.4	2.1	2.1	1.4	1.5
Average weekly beer plus cider intake	1.4	2.0	3.4	-0.8	-1.8
Impedance of whole body	1.4	7.0	11.5	-1.6	-3.4
Prostate Cancer	1.3	1.8	2.5	-1.1	-1.6
Fasting Glucose	1.3	1.5	2.5	1.6	0.7
Number of treatments/medications taken	1.3	2.4	3.5	1.1	1.9
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	1.8	-1.3	-1.3
Systolic blood pressure, automated reading	1.3	3.7	5.4	2.3	1.4
Blood clot in the leg (DVT)	1.3	1.6	2.5	1.6	0.8
Breast Cancer	1.2	2.9	3.9	-1.4	-2.0
Body Mass Index (BMI) (2010)	1.2	1.6	3.1	-1.8	-0.4
HbA1C	1.2	1.3	1.6	1.0	1.3
Waist Hip Ratio (WHR)	1.2	5.2	5.5	2.2	2.3
Allergy or Eczema	1.2	3.2	4.2	-2.0	-1.5
Tense / ‘highly strung’	1.2	2.0	2.3	-1.3	-1.5
Pulse wave reflection index	1.2	1.5	1.7	-1.3	-1.1
Ever had bowel cancer screening	1.2	1.4	2.1	-0.9	-1.4
Osteoporosis (self-reported)	1.2	1.4	2.3	-1.5	-0.7
Basal cell carcinoma (self-reported)	1.2	1.4	2.1	1.5	0.9
Relative age of first facial hair	1.1	2.3	2.9	1.7	1.3
Impedance of leg (right)	1.1	5.5	9.4	-1.3	-3.1
Stomach or abdominal pain in last month	1.1	1.3	2.6	1.6	0.2
Weight	1.1	5.5	7.3	-2.7	-1.9
Falls in the last year	1.1	1.4	2.9	-0.2	-1.7
Depression (self-reported)	1.1	1.3	2.1	-0.6	-1.5
Lung cancer (father)	1.1	1.2	1.3	1.1	1.1
Intelligence (Savage-Jansen 2018)	1.0	3.2	5.0	1.2	2.2
Blood White Count	1.0	7.7	7.8	-2.8	-2.7
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.5	-0.6	-1.6
Sitting height	1.0	7.0	10.4	-1.9	-3.2
Impedance of leg (left)	1.0	4.8	8.4	-1.1	-2.9
Hypothyroidism/myxoedema (self-reported)	1.0	2.0	2.5	-1.2	-1.6
High blood pressure (siblings)	1.0	1.5	2.2	0.8	1.5
Body fat percentage	1.0	3.9	4.8	-2.2	-1.8
Medication: Ibuprofen	1.0	1.2	1.4	1.2	1.0
Whole body fat mass	1.0	4.2	5.4	-2.3	-1.7
Long-standing illness, disability or infirmity	1.0	1.5	1.5	1.2	1.2
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	2.2	1.5	0.7
Neuroticism (Nagel 2018)	0.9	2.2	4.2	-0.5	-2.0
Type 2 Diabetes (T2D) (2012)	0.9	1.1	1.3	1.1	1.0
Current tobacco smoking	0.9	1.5	1.6	-1.2	-1.2
Medication: Levothyroxine sodium	0.9	1.5	1.7	-1.2	-1.3
Pulse rate	0.9	1.5	1.8	-1.3	-1.1
Medication: Amlodipine	0.9	1.3	2.5	0.2	1.6
Medication: Seretide 50 evohaler	0.9	1.0	2.0	0.1	1.4
Mother’s age at death	0.9	1.1	1.6	-0.8	-1.3
Hair Pigment	0.8	22.9	25.5	4.5	5.0
Sensitivity / hurt feelings	0.8	1.4	2.5	-0.5	-1.6
Severe depression (siblings)	0.8	0.9	1.5	-0.5	-1.2
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	1.0	-0.9	-1.0
Multivitamins +/- minerals	0.8	1.0	1.9	0.1	-1.4
Chronic bronchitis/emphysema (father)	0.8	0.9	1.3	-0.7	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	1.2	1.1	0.8
Alcohol intake frequency.	0.8	1.8	2.7	-1.6	-1.0
Diastolic blood pressure, automated reading	0.8	2.5	2.9	1.7	1.5
Depressed Affect (Nagel 2018)	0.7	1.4	2.5	-0.5	-1.6
Alzheimer’s Disease (in mother)	0.7	0.8	1.1	-1.0	-0.7
Ulcerative Colitis (UC)	0.7	1.2	1.5	-1.0	-1.2
Ulcerative Colitis	0.7	1.0	1.1	-1.0	-1.1
Financial difficulties in last 2 years	0.7	1.0	1.9	-0.3	-1.4
Pain all over the body in last month	0.7	0.8	1.1	0.7	1.0
Hair/balding pattern: Pattern 3	0.7	1.0	1.1	-1.1	-1.0
Medication: Ventolin 100micrograms inhaler	0.7	1.0	1.4	-1.2	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.3	-1.1	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	2.1	-0.8	-1.4
Eye problems/disorders: Cataract	0.7	0.8	1.1	0.8	1.0
Medication for cholesterol	0.7	1.1	2.0	-0.5	-1.4
Guilty feelings	0.7	1.0	1.2	1.1	0.9
Wears glasses or contact lenses	0.7	0.9	1.6	-0.4	1.2
Arm predicted mass (left)	0.7	3.7	5.2	-2.3	-1.5
Blood Red Count	0.6	6.2	7.9	-2.8	-2.1
Hypothyroidism (self reported)	0.6	1.4	1.4	-1.2	-1.2
Vitamin and mineral supplements	0.6	0.8	1.7	-0.1	1.3
Maternal smoking around birth	0.6	0.8	1.6	0.3	-1.3
Had menopause	0.6	0.8	1.3	-1.1	-0.5
Medication: Lansoprazole	0.6	0.7	1.1	0.6	1.0
Illnesses of mother	0.6	0.7	0.8	0.8	0.9
Gout (self-reported)	0.6	0.8	1.3	0.6	1.1
Leg fat percentage (right)	0.6	2.2	2.9	-1.7	-1.2
Emphysema/chronic bronchitis	0.6	0.7	0.7	-0.9	-0.8
Mean time to correctly identify matches	0.6	1.2	2.0	-1.4	-0.7
Suffer from ‘nerves’	0.6	0.9	1.0	-1.0	-0.9
Average weekly red wine intake	0.6	0.9	1.7	-1.3	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	0.8	-0.7	-0.9
Mineral and other dietary supplements	0.6	0.8	1.3	0.5	1.1
Ever taken oral contraceptive pill	0.6	0.7	1.4	0.0	-1.2
Hearing aid user	0.6	0.7	1.3	0.2	1.2
Arm fat-free mass (left)	0.6	3.1	4.5	-2.1	-1.3
Number of operations (self-reported)	0.6	0.8	0.9	-0.9	-0.9
Myopia	0.6	0.9	1.7	-1.3	-0.2
Major Depression (MDD)	0.5	0.6	0.7	-0.8	-0.8
Triglycerides	0.5	0.8	1.2	-1.1	-0.7
Lung FVC	0.5	2.4	3.8	-1.0	-2.0
Hand grip strength (left)	0.5	1.2	1.8	-1.3	-0.8
Trunk fat-free mass	0.5	2.8	3.9	-2.0	-1.3
Arm fat mass (right)	0.5	2.3	3.8	-1.9	-0.8
Trunk predicted mass	0.5	3.1	4.4	-2.1	-1.4
Length of working week for main job	0.5	0.5	0.5	0.7	0.7
Exposure to tobacco smoke at home	0.5	0.5	0.6	-0.7	-0.8
Leg fat mass (right)	0.5	2.0	2.8	-1.7	-1.1
Miserableness	0.5	0.8	1.2	1.1	0.7
Tinnitus: Yes, now most or all of the time	0.5	0.6	0.6	0.8	0.7
Basal metabolic rate	0.5	2.8	4.2	-2.0	-1.2
Commuting to job workplace: Cycle	0.5	0.6	1.1	1.0	0.3
Pain experienced in last month	0.5	0.8	1.0	-1.0	-0.7
Heart disease (siblings)	0.5	0.6	1.0	0.5	1.0
Leg fat mass (left)	0.5	2.0	3.0	-1.7	-1.0
Crohns Disease (2017)	0.4	0.8	1.0	0.8	1.0
Reaction Time	0.4	0.8	1.3	-1.1	-0.5
BMI	0.4	2.2	4.0	-2.0	-0.7
Neuroticism	0.4	1.0	1.6	-0.7	-1.3
Average weekly spirits intake	0.4	0.5	1.0	-1.0	0.0
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	0.8	0.1	-0.9
Qualifications: CSEs or equivalent	0.4	0.5	0.8	-0.5	-0.9
Serious illness, injury or assault to yourself	0.4	0.5	0.9	1.0	0.4
High blood pressure (mother)	0.4	0.5	0.6	0.8	0.7
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.8	0.3	-0.9
Allergy	0.4	0.9	1.3	1.1	0.6
Arm fat percentage (right)	0.4	1.8	2.6	-1.6	-1.0
Loud music exposure frequency	0.4	0.4	0.9	0.0	-0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	0.8	-0.9	0.6
Exposure to tobacco smoke outside home	0.4	0.6	0.9	0.9	0.5
Arm predicted mass (right)	0.4	2.2	3.8	-2.0	-0.7
Comparative height size at age 10	0.4	2.1	2.9	-1.7	-1.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	0.9	-0.2	0.9
Supplements: Vitamin C	0.4	0.5	0.6	-0.7	-0.8
Illnesses of siblings: Diabetes	0.4	0.5	1.0	0.0	1.0
Whole body fat-free mass	0.4	2.3	3.5	-1.9	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	0.7	0.9	-0.7
Illnesses of father: None of the above (group 1)	0.4	0.5	1.0	-0.2	-1.0
Whole body water mass	0.4	2.4	3.7	-1.9	-1.0
Arm fat mass (left)	0.4	1.8	3.1	-1.8	-0.8
Commuting to job workplace: Public transport	0.4	0.5	0.8	-0.9	0.4
Leg fat percentage (left)	0.4	1.5	2.1	-1.5	-1.0
Schizophrenia (2018)	0.3	0.6	1.1	-1.1	-0.4
Schizophrenia (2014)	0.3	0.7	0.7	-0.8	-0.9
Blood Eosinophil Count	0.3	2.1	2.8	1.7	1.2
Respiratory disease	0.3	0.6	1.0	-1.0	-0.4
Ever had hysterectomy (womb removed)	0.3	0.4	0.7	-0.1	0.8
Diabetes (mother)	0.3	0.4	0.5	0.4	0.7
Leg fat-free mass (left)	0.3	1.8	3.0	-1.7	-0.8
Leg predicted mass (left)	0.3	1.4	2.5	-1.6	-0.6
Waist circumference	0.3	0.9	1.9	-1.4	0.0
Nervous feelings	0.3	0.6	0.7	-0.6	-0.9
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.5	0.6	0.7
Noisy workplace	0.3	0.4	0.6	0.8	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	1.3	-0.8	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.8	-0.0	-0.9
Hair/balding pattern: Pattern 4	0.3	0.7	0.7	-0.8	-0.9
Arm fat-free mass (right)	0.3	1.6	2.8	-1.7	-0.7
Comparative body size at age 10	0.3	0.8	1.4	-1.2	-0.4
Pulse rate, automated reading	0.3	1.1	1.7	0.7	1.3
Leg pain on walking	0.3	0.4	0.4	0.6	0.6
Arm fat percentage (left)	0.3	1.4	2.3	-1.5	-0.7
Commuting to job workplace: Walk	0.3	0.3	0.5	-0.7	-0.3
Age started oral contraceptive pill	0.3	0.4	0.5	0.5	0.7
Alcohol drinker status: Previous	0.3	0.3	0.4	-0.6	-0.5
Alzheimer’s Disease (in father)	0.2	0.2	0.5	-0.2	0.7
Rheumatoid Arthritis	0.2	0.2	0.4	-0.6	0.3
Blood Platelet Count	0.2	2.2	3.3	1.8	1.0
Townsend deprivation index at recruitment	0.2	0.3	0.4	0.6	-0.4
Average weekly fortified wine intake	0.2	0.2	0.3	0.5	0.5
Relative age voice broke	0.2	0.3	0.6	0.3	0.8
Taking other prescription medications	0.2	0.3	0.4	0.4	0.6
Supplements: Glucosamine	0.2	0.2	0.4	0.1	-0.6
Qualifications: None of the above	0.2	0.4	0.6	0.6	-0.7
Illnesses of siblings	0.2	0.3	0.5	-0.3	-0.7
Number of live births	0.2	0.3	0.6	-0.0	0.8
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.1	-0.4	-1.0
Peak expiratory flow (PEF)	0.2	0.4	0.7	0.8	0.0
Headache pain in last month	0.2	0.4	0.5	0.7	0.5
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.3	-0.5	-0.6
Wheeze or whistling in the chest in last year	0.2	0.3	0.4	-0.4	-0.7
Shortness of breath walking on level ground	0.2	0.3	0.3	-0.5	-0.6
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.3	-0.5	0.6
Leg fat-free mass (right)	0.2	1.2	2.1	-1.4	-0.5
Mood swings	0.2	0.3	0.6	-0.0	-0.8
Qualifications: nursing, teaching	0.2	0.3	0.5	0.7	0.2
Breast cancer (self-reported)	0.2	0.2	0.4	0.2	0.6
Asthma (self-reported)	0.2	0.4	0.5	-0.7	-0.7
Leg predicted mass (right)	0.2	1.1	1.9	-1.4	-0.4
Financial situation satisfaction	0.2	0.3	0.5	0.3	-0.7
Illnesses of father: High blood pressure	0.2	0.3	0.3	-0.5	0.6
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.3	0.5	0.6
Supplements: Calcium	0.2	0.2	0.3	-0.0	-0.6
Bipolar Disorder or Schizophrenia	0.1	0.3	0.4	-0.6	-0.3
Schizophrenia vs Biploar Disorder	0.1	0.2	0.2	-0.4	0.4
Irritable Bowel Disease (IBD)	0.1	0.3	0.4	-0.5	-0.6
Ovarian Cancer	0.1	0.1	0.1	-0.3	0.3
Age at First Birth	0.1	0.1	0.2	-0.4	-0.1
Bipolar Disorder (2011)	0.1	0.1	0.1	0.2	0.3
Coronary Artery Disease (CAD)	0.1	0.1	0.2	0.4	-0.3
Mean Putamen Volume	0.1	0.1	0.2	-0.5	-0.2
Neuroticism (2016)	0.1	0.2	0.2	0.4	-0.4
Heel T-Score	0.1	0.5	0.9	-0.1	-1.0
Supplements: Zinc	0.1	0.1	0.1	0.2	-0.4
Hand grip strength (right)	0.1	0.2	0.2	-0.5	0.3
Fed-up feelings	0.1	0.1	0.1	0.4	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.4	0.5	-0.6
Body mass index (BMI)	0.1	0.5	0.6	-0.7	0.8
Hair/balding pattern: Pattern 2	0.1	0.2	0.3	0.3	0.5
Had other major operations	0.1	0.1	0.1	-0.3	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.3	0.5	-0.3
Neuroticism score	0.1	0.2	0.5	0.0	-0.7
Worrier / anxious feelings	0.1	0.2	0.3	0.2	-0.5
Asthma	0.1	0.1	0.2	-0.3	-0.4
Number of full brothers	0.1	0.1	0.2	0.4	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	0.1	-0.5
Number of children fathered	0.1	0.1	0.2	0.2	0.5
Qualifications: College or University degree	0.1	0.2	0.3	-0.4	-0.6
Migraine (self-reported)	0.1	0.1	0.1	0.4	-0.0
Medication: Omeprazole	0.1	0.2	0.3	-0.6	-0.0
Number of full sisters	0.1	0.1	0.1	-0.4	0.3
Family relationship satisfaction	0.1	0.1	0.2	0.4	0.3
Knee pain experienced in last month	0.1	0.2	0.2	0.4	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	-0.1	0.5
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.4	0.2
Back pain experienced in last month	0.1	0.1	0.2	0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.6	-0.8	-0.1
Average weekly champagne plus white wine intake	0.1	0.1	0.3	0.5	-0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.3	-0.6	0.1
Bipolar Disorder (2018)	0.0	0.0	0.1	0.3	-0.1
Crohns Disease (2012)	0.0	0.1	0.1	0.1	0.4
Tanning	0.0	0.4	0.5	-0.6	-0.7
Alcohol intake versus 10 years previously	0.0	0.0	0.0	0.1	0.0
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.1	0.3	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.0	0.2	0.2
Age at first live birth	0.0	0.0	0.0	-0.0	-0.1
Medication: Allopurinol	0.0	0.0	0.0	0.1	-0.2
Heart disease (mother)	0.0	0.0	0.0	0.1	-0.0
Had major operations	0.0	0.0	0.0	0.2	0.1
Age at last live birth	0.0	0.0	0.1	0.1	-0.3
Commuting to job workplace: Car/motor vehicle	0.0	0.1	0.1	0.2	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.0	-0.2	0.0
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.0	-0.1	0.0
Unable to work because of sickness or disability	0.0	0.0	0.1	-0.0	-0.3

Hub : Genes

LOC100272146

Models

Trait associations