TWAS hub - LOC113230

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.077	0.025	0.00011	0.116	0.024	0.109	0.098	0.114	5.3e-14	0.00061	3.9e-13	6.7e-12	1.1e-13
2	TCGA	Thyroid Carcinoma	0.047	0.023	0.00075	0.007	0.035	0.027	NA	0.019	5.8e-02	0.00023	1.1e-03	NA	5.3e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Pack years of smoking	8.8	13.0	14.6	-3.4	3.8
Pack years adult smoking proportion	8.3	12.6	13.9	-3.4	3.7
Had menopause	6.5	8.1	8.5	-2.8	2.9
Hearing difficulty/problems with background noise	5.0	7.9	8.1	2.8	-2.9
Number of full brothers	4.8	6.0	9.7	3.1	-1.6
Worry too long after embarrassment	4.4	7.3	7.9	-2.6	2.8
Financial difficulties in last 2 years	4.0	5.3	5.6	-2.4	2.3
Blood Red Count	3.8	36.3	46.8	6.8	-5.1
Guilty feelings	3.8	5.7	7.6	-2.0	2.8
Smoking status: Previous	3.7	5.6	7.0	2.1	-2.6
Length of working week for main job	3.6	4.0	6.0	2.5	-1.4
Age at last live birth	3.6	5.2	6.1	2.5	-2.1
Exposure to tobacco smoke at home	3.2	3.6	5.3	-2.3	1.4
Smoking status: Current	3.0	4.8	5.9	-2.4	1.9
Mouth/teeth dental problems	2.9	4.5	6.1	2.5	-1.7
Depression (self-reported)	2.9	3.5	4.5	1.6	-2.1
Lung FEV1/FVC ratio	2.8	14.2	17.5	-4.2	3.3
Average weekly spirits intake	2.8	3.5	3.9	-1.8	2.0
Hearing difficulty/problems: Yes	2.8	4.3	5.3	1.8	-2.3
Hypothyroidism/myxoedema (self-reported)	2.7	5.3	5.5	-2.4	2.3
Ever smoked	2.7	4.8	7.4	1.5	-2.7
Comparative body size at age 10	2.6	7.2	10.5	-1.9	3.2
Lupus	2.5	3.8	5.1	2.3	-1.6
Happiness	2.5	3.0	3.1	-1.8	1.7
Age at first live birth	2.5	4.4	5.3	2.3	-1.9
Alzheimer’s Disease (including proxy)	2.4	3.5	4.1	2.0	-1.7
Father’s age at death	2.4	3.2	4.2	1.5	-2.1
Breastfed as a baby	2.4	3.0	4.2	1.4	-2.0
Mouth/teeth dental problems: Bleeding gums	2.4	3.1	4.0	-2.0	1.5
Alcohol drinker status: Never	2.4	2.9	3.3	1.8	-1.6
Hypothyroidism (self reported)	2.3	5.2	5.3	-2.3	2.3
Hand grip strength (left)	2.2	5.7	8.3	1.8	-2.9
Current tobacco smoking	2.2	3.7	3.9	-2.0	1.8
Leg fat percentage (left)	2.2	7.9	11.2	-3.3	2.1
Past tobacco smoking	2.0	3.7	6.1	-1.2	2.5
Hearing aid user	2.0	2.3	2.5	1.4	-1.6
Other serious medical condition/disability diagnosed by doctor	1.9	2.4	3.0	1.7	-1.4
Severe depression (siblings)	1.9	2.2	2.2	-1.5	1.5
Leg fat percentage (right)	1.9	6.9	9.7	-3.1	2.0
Medication: Lansoprazole	1.8	2.1	3.1	1.0	-1.8
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	2.4	1.6	-1.5
Arm fat percentage (right)	1.7	6.6	8.4	-2.9	2.2
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.2	3.3	1.1	-1.8
Alzheimer’s Disease (in mother)	1.6	1.9	2.5	1.6	-1.1
Alzheimer’s Disease (in father)	1.6	1.8	2.4	1.6	-1.1
Age when periods started (menarche)	1.6	3.9	4.6	2.1	-1.8
Frequency of tenseness / restlessness in last 2 weeks	1.6	2.5	2.8	-1.5	1.7
Body fat percentage	1.6	6.2	8.4	-2.9	2.0
Depression (Nagel 2018)	1.5	2.3	2.5	-1.6	1.4
Diabetes (father)	1.5	1.8	2.2	-1.2	1.5
Ever used hormone-replacement therapy (HRT)	1.4	1.8	2.4	-1.5	1.1
Trunk fat percentage	1.4	5.5	7.3	-2.7	1.9
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	2.5	0.7	-1.6
Chronic bronchitis/emphysema (father)	1.4	1.6	3.2	-0.2	1.8
High blood pressure (mother)	1.4	2.0	2.2	1.4	-1.5
Mouth/teeth dental problems: Dentures	1.4	2.3	3.5	-1.9	1.1
Blood clot in the leg (DVT)	1.4	1.9	1.9	1.4	-1.3
Exposure to tobacco smoke outside home	1.4	1.9	2.1	-1.3	1.5
Arm fat percentage (left)	1.4	5.8	7.5	-2.7	2.0
Townsend deprivation index at recruitment	1.3	1.8	2.2	-1.5	1.2
Medication: Ventolin 100micrograms inhaler	1.3	1.7	3.1	-0.6	1.7
Medication: Omeprazole	1.3	1.5	2.7	-1.6	0.6
Heart disease (mother)	1.3	1.6	1.8	-1.1	1.4
Forced vital capacity (FVC)	1.2	4.8	4.8	2.2	-2.2
Prospective memory result	1.2	1.5	1.7	1.3	-1.1
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.0	-0.9	1.4
Forced vital capacity (FVC), Best measure	1.2	4.5	4.7	2.2	-2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.3	1.9	-1.4	0.9
Number of self-reported non-cancer illnesses	1.2	2.1	2.1	1.4	-1.4
Average weekly champagne plus white wine intake	1.2	1.7	2.0	-1.4	1.2
High cholesterol (Self-reported)	1.2	2.0	3.1	-1.8	1.0
Leg fat mass (left)	1.2	4.6	6.8	-2.6	1.6
Medication: Levothyroxine sodium	1.1	1.8	2.8	-1.7	1.0
Body mass index (BMI)	1.1	4.5	6.0	-2.4	1.7
Medication: Simvastatin	1.1	1.7	2.9	-1.7	0.7
Arm fat mass (right)	1.1	4.5	5.9	-2.4	1.8
High blood pressure (siblings)	1.1	1.6	1.8	-1.3	1.2
Emphysema/chronic bronchitis	1.1	1.2	1.4	-1.0	1.2
Whole body fat mass	1.1	4.7	6.5	-2.5	1.7
Leg fat mass (right)	1.1	4.4	6.2	-2.5	1.6
Loneliness, isolation	1.1	1.5	2.2	0.9	-1.5
Respiratory disease	1.0	2.3	3.1	1.7	-1.3
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	2.0	1.4	-0.8
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	1.8	-1.4	1.2
Illnesses of mother	1.0	1.3	1.9	-0.8	1.4
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	2.2	1.5	-1.0
Mouth/teeth dental problems: Loose teeth	1.0	1.2	2.0	-1.4	0.7
Risk taking	1.0	1.5	2.2	1.5	-0.9
Age started oral contraceptive pill	1.0	1.2	1.7	-1.3	0.9
Unable to work because of sickness or disability	1.0	1.3	2.0	1.4	-0.8
Hand grip strength (right)	0.9	2.5	4.0	1.0	-2.0
Alcohol intake versus 10 years previously	0.9	1.4	2.6	-1.6	0.3
Falls in the last year	0.9	1.3	2.4	-0.4	-1.5
Noisy workplace	0.9	1.1	1.8	-1.3	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	1.9	-0.4	1.4
Shortness of breath walking on level ground	0.9	1.1	1.1	1.0	-1.0
Overall health rating	0.9	1.8	2.5	-1.6	1.1
Illness, injury, bereavement, stress in last 2 years	0.9	1.0	1.2	1.1	-0.9
Arm fat mass (left)	0.9	3.6	5.1	-2.2	1.5
Commuting to job workplace: Public transport	0.9	1.1	1.7	-1.3	0.7
Medication: Atorvastatin	0.9	1.1	2.2	-0.2	1.5
Cholesterol lowering medication	0.9	1.3	1.4	-1.2	1.1
Chronotype (morning person)	0.8	1.9	3.0	-1.7	0.9
Frequency of depressed mood in last 2 weeks	0.8	1.2	1.3	-1.1	1.0
Trunk fat mass	0.8	3.6	5.0	-2.2	1.5
Alcohol usually taken with meals	0.8	1.3	2.2	-0.6	1.5
Lung cancer (father)	0.8	0.9	1.5	-0.6	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.5	2.8	1.5	-1.7
Number of children fathered	0.8	0.9	1.1	-0.8	1.1
Height	0.7	13.1	17.6	4.2	-2.9
Waist Hip Ratio (WHR)	0.7	3.2	3.8	1.6	-1.9
Tanning	0.7	8.2	10.0	2.5	-3.2
Angina	0.7	0.9	1.6	-0.5	1.3
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	1.3	-0.7	1.1
Pulse wave Arterial Stiffness index	0.7	0.8	1.0	1.0	-0.8
Migraine (self-reported)	0.7	0.9	1.4	1.2	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	1.1	-1.1	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	0.9	-1.0	0.7
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	1.6	0.7	-1.3
Alcohol drinker status: Previous	0.7	0.8	1.1	1.1	-0.6
Had other major operations	0.6	0.7	0.8	0.9	-0.8
Standing height	0.6	5.6	6.0	2.5	-2.3
Peak expiratory flow (PEF)	0.6	1.4	1.7	1.0	-1.3
Health satisfaction	0.6	0.8	0.9	1.0	-0.8
Angina (self-reported)	0.6	0.7	1.4	-0.3	1.2
Leg pain on walking	0.6	0.7	0.8	0.9	-0.8
Supplements: Vitamin C	0.6	0.7	1.1	-1.0	0.6
Diabetes diagnosed by doctor	0.6	1.0	1.5	-0.7	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	0.9	-0.7	0.9
Back pain experienced in last month	0.6	0.9	1.3	1.1	-0.7
Ever taken oral contraceptive pill	0.6	0.6	1.3	-1.1	0.1
Medication: Paracetamol	0.6	0.9	1.8	0.1	-1.3
Illnesses of father: High blood pressure	0.6	0.8	0.8	0.9	-0.9
Fasting Glucose	0.5	0.6	1.3	0.0	1.1
Blood Platelet Count	0.5	5.6	7.0	-2.6	2.0
BMI	0.5	2.6	3.0	-1.7	1.5
Ever had hysterectomy (womb removed)	0.5	0.6	0.8	0.9	-0.6
Diabetes (mother)	0.5	0.6	1.2	-1.1	-0.2
Maternal smoking around birth	0.5	0.7	1.3	-0.1	1.2
Stomach or abdominal pain in last month	0.5	0.6	1.0	1.0	-0.4
Sitting height	0.5	3.2	4.1	2.0	-1.5
Waist circumference	0.5	1.7	2.4	-1.6	1.0
Hip circumference	0.5	2.1	2.2	-1.5	1.4
Wheeze or whistling in the chest in last year	0.5	0.9	0.9	0.9	-1.0
Qualifications: College or University degree	0.5	1.6	2.8	1.7	-0.7
Medication: Ibuprofen	0.5	0.6	1.2	0.2	-1.1
Knee pain experienced in last month	0.5	0.8	1.2	-1.1	0.6
Eye problems/disorders: Cataract	0.5	0.6	1.1	0.3	-1.1
Medication for cholesterol	0.5	0.7	1.0	1.0	-0.7
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.2	0.2	1.1
Ovarian Cancer	0.4	0.5	1.0	0.0	1.0
Relative age of first facial hair	0.4	0.8	0.9	0.9	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	0.9	-0.9	0.3
Medication: Atenolol	0.4	0.5	0.9	-0.3	0.9
Number of incorrect matches in round	0.4	0.6	1.3	1.1	0.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	1.6	1.2	-1.3
Medication: Cholesterol lowering	0.4	0.7	1.2	-0.3	1.1
Medication: Allopurinol	0.4	0.5	0.7	0.5	-0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	0.7	-0.8	0.5
Number of full sisters	0.4	0.5	0.8	-0.9	0.5
Chest pain or discomfort	0.4	0.6	0.8	-0.9	0.7
Commuting to job workplace: Walk	0.4	0.4	0.9	0.9	0.1
Average weekly beer plus cider intake	0.4	0.6	1.2	-0.2	-1.1
Diastolic blood pressure, automated reading	0.4	1.3	1.4	-1.2	1.1
Breast Cancer	0.3	0.7	0.7	0.8	-0.8
Prostate Cancer	0.3	0.4	0.5	-0.7	0.5
Lung FVC	0.3	1.3	1.9	1.4	-0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.5	0.3	-0.7
Average weekly fortified wine intake	0.3	0.4	0.7	0.9	-0.2
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.6	0.7	-0.4
Diabetes (self-reported)	0.3	0.4	0.8	-0.3	0.9
Medication: Ramipril	0.3	0.4	0.6	-0.5	0.8
Time employed in main current job	0.3	0.4	0.7	0.9	-0.0
Hair/balding pattern: Pattern 3	0.3	0.5	0.6	-0.6	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.7	-0.6	0.8
Hair/balding pattern: Pattern 4	0.3	0.7	1.1	1.0	-0.6
Pulse wave reflection index	0.3	0.4	0.7	-0.3	0.8
Loud music exposure frequency	0.3	0.3	0.7	-0.1	-0.8
Headache pain in last month	0.3	0.6	0.9	-0.9	-0.6
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	0.8	-0.9	-0.3
Pulse wave peak to peak time	0.3	0.4	0.5	-0.7	0.5
Medication for pain relief, constipation, heartburn	0.3	0.4	0.8	0.9	-0.2
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.5	0.4	-0.7
Wears glasses or contact lenses	0.3	0.3	0.7	-0.2	0.8
Mother’s age at death	0.3	0.4	0.8	0.9	-0.2
Eye problems/disorders: Glaucoma	0.3	0.3	0.5	0.4	-0.7
Medication: Bendroflumethiazide	0.3	0.4	0.5	0.7	-0.6
Supplements: Calcium	0.3	0.3	0.6	0.8	-0.3
Heart disease (siblings)	0.3	0.4	0.7	0.9	-0.3
Verbal and Numeric Reasoning (VNR)	0.2	0.4	0.5	0.7	-0.5
Neuroticism (2016)	0.2	0.3	0.4	-0.6	0.4
Blood Eosinophil Count	0.2	1.7	3.3	0.3	1.8
Smoking Status	0.2	0.4	0.8	-0.1	-0.9
Neuroticism	0.2	0.4	0.5	-0.5	0.7
Supplements: Zinc	0.2	0.3	0.5	0.2	-0.7
Medication: Metformin	0.2	0.3	0.4	-0.3	0.7
Hair/balding pattern: Pattern 2	0.2	0.2	0.3	-0.5	-0.4
Weight	0.2	0.8	1.3	-1.1	0.6
Trunk fat-free mass	0.2	1.3	1.8	0.9	-1.3
Qualifications: A levels/AS levels or equivalent	0.2	0.5	0.9	0.2	-1.0
Asthma	0.2	0.3	0.4	0.5	-0.7
Trunk predicted mass	0.2	1.3	1.7	0.9	-1.3
Medication: Paracetamol	0.2	0.3	0.4	-0.5	-0.6
Arm fat-free mass (right)	0.2	0.9	1.5	0.5	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.5	-0.0	0.7
Neck or shoulder pain in last month	0.2	0.2	0.4	-0.2	-0.6
Suffer from ‘nerves’	0.2	0.3	0.3	-0.6	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.0	0.1	-1.0
Average weekly red wine intake	0.2	0.3	0.6	-0.8	-0.1
Friendships satisfaction	0.2	0.3	0.4	-0.4	0.6
Mineral and other dietary supplements	0.2	0.3	0.4	-0.4	0.6
Breast cancer (self-reported)	0.2	0.2	0.2	-0.4	-0.5
Asthma (self-reported)	0.2	0.4	0.5	0.6	-0.7
Medication: Aspirin	0.2	0.3	0.4	0.6	-0.4
Medication: Gliclazide	0.2	0.3	0.5	-0.7	0.3
Miserableness	0.2	0.3	0.4	0.6	-0.4
Medication: Blood pressure	0.2	0.5	0.7	-0.5	0.8
Ever depressed for a whole week	0.2	0.2	0.3	-0.5	0.5
Commuting to job workplace: Cycle	0.2	0.2	0.4	0.7	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.5	-0.7	-0.1
Pain experienced in last month	0.2	0.4	0.4	-0.6	0.6
Depressed Affect (Nagel 2018)	0.1	0.3	0.5	0.7	-0.3
Neuroticism (Nagel 2018)	0.1	0.2	0.2	-0.3	0.5
Worry (Nagel 2018)	0.1	0.3	0.4	0.3	-0.7
Irritable Bowel Disease (IBD)	0.1	0.3	0.5	0.3	-0.7
Ulcerative Colitis (UC)	0.1	0.3	0.3	-0.5	-0.5
Reaction Time	0.1	0.2	0.3	0.1	0.6
Age at First Birth	0.1	0.2	0.3	-0.6	0.0
HbA1C	0.1	0.1	0.1	0.3	0.0
Primary Biliary Cirrhosis	0.1	0.2	0.3	-0.6	0.0
Heel T-Score	0.1	0.5	1.0	1.0	-0.3
Allergy or Eczema	0.1	0.3	0.5	0.0	-0.7
Number of treatments/medications taken	0.1	0.1	0.2	-0.0	-0.5
Sensitivity / hurt feelings	0.1	0.1	0.2	0.4	0.2
Vitamin and mineral supplements	0.1	0.1	0.2	0.1	-0.5
Medication: Co-codamol	0.1	0.1	0.1	-0.3	-0.2
Impedance of leg (right)	0.1	0.3	0.6	0.1	-0.8
Fed-up feelings	0.1	0.2	0.5	0.1	0.7
Relative age voice broke	0.1	0.1	0.2	-0.5	-0.1
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	-0.3	-0.3
Serious illness, injury or assault to yourself	0.1	0.1	0.2	0.0	0.4
High blood pressure	0.1	0.1	0.2	-0.3	0.5
Supplements: Glucosamine	0.1	0.1	0.2	-0.4	0.1
Impedance of leg (left)	0.1	0.3	0.5	-0.2	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.2	-0.4	-0.5
Qualifications: None of the above	0.1	0.2	0.4	-0.1	-0.6
Heart attack	0.1	0.1	0.1	0.4	-0.1
Impedance of arm (right)	0.1	0.3	0.7	-0.2	0.8
Number of live births	0.1	0.1	0.1	-0.4	0.2
Tense / ‘highly strung’	0.1	0.1	0.2	0.4	-0.3
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.1	0.3	-0.2
Medication: Amlodipine	0.1	0.1	0.2	-0.4	0.4
Birth weight	0.1	0.1	0.2	0.2	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.3	-0.5	-0.3
Medication: Blood pressure	0.1	0.1	0.2	0.2	0.4
Medication: Seretide 50 evohaler	0.1	0.1	0.2	-0.5	0.3
Mean time to correctly identify matches	0.1	0.3	0.6	0.7	0.1
Arm predicted mass (right)	0.1	0.7	1.3	0.3	-1.1
Pulse rate, automated reading	0.1	0.4	0.7	0.1	-0.8
Alcohol intake frequency.	0.1	0.2	0.2	0.5	-0.3
Family relationship satisfaction	0.1	0.2	0.3	-0.5	0.3
Medication: Aspirin	0.1	0.2	0.3	0.5	-0.3
Illnesses of father: Heart disease	0.1	0.1	0.2	0.0	-0.4
Illnesses of siblings: Diabetes	0.1	0.1	0.1	-0.4	0.4
Whole body fat-free mass	0.1	0.4	0.6	0.5	-0.8
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.1	-0.3	-0.3
Mood swings	0.1	0.2	0.3	0.2	0.5
Long-standing illness, disability or infirmity	0.1	0.1	0.2	-0.0	-0.5
Qualifications: nursing, teaching	0.1	0.2	0.3	0.2	0.5
Illnesses of father: None of the above (group 1)	0.1	0.1	0.1	0.3	-0.3
Whole body water mass	0.1	0.3	0.5	0.4	-0.7
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.1	-0.3	0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.1	0.2	-0.3
Number of operations (self-reported)	0.1	0.2	0.2	0.4	-0.5
Fractured/broken bones in last 5 years	0.1	0.1	0.2	0.4	-0.3
Myopia	0.1	0.2	0.3	0.6	-0.2
Basal cell carcinoma (self-reported)	0.1	0.2	0.3	0.0	-0.6
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.1	-0.3	-0.1
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2017)	0.0	0.1	0.2	0.5	-0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0
Blood White Count	0.0	0.3	0.6	-0.2	0.8
Systolic Blood Pressure	0.0	0.1	0.1	-0.4	-0.1
Cardiovascular Disease	0.0	0.1	0.2	-0.4	-0.2
Type 2 Diabetes (T2D) (2018)	0.0	0.1	0.1	0.3	-0.1
Hair Pigment	0.0	1.0	1.1	-1.0	1.0
Systolic blood pressure, automated reading	0.0	0.0	0.0	-0.1	-0.1
Medication for hormone replacement therapy	0.0	0.0	0.0	-0.1	-0.0
Leg fat-free mass (left)	0.0	0.0	0.0	0.0	0.1
Taking other prescription medications	0.0	0.0	0.0	-0.1	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.2	-0.4	-0.1
Qualifications: CSEs or equivalent	0.0	0.0	0.0	0.1	-0.0
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.2	0.1	-0.4
Multivitamins +/- minerals	0.0	0.0	0.0	-0.2	0.2
Leg predicted mass (left)	0.0	0.0	0.0	0.1	-0.0
Nervous feelings	0.0	0.0	0.1	-0.1	0.2
Allergy	0.0	0.0	0.1	0.2	0.1
Pain all over the body in last month	0.0	0.0	0.0	-0.2	-0.1
Fluid intelligence score	0.0	0.0	0.0	-0.1	0.1
Illnesses of siblings	0.0	0.1	0.1	-0.1	-0.3
Neuroticism score	0.0	0.1	0.1	-0.3	0.1
Worrier / anxious feelings	0.0	0.0	0.1	-0.3	0.1
Pulse rate	0.0	0.1	0.1	-0.2	-0.3
Impedance of arm (left)	0.0	0.1	0.1	0.4	0.1
Birth weight of first child	0.0	0.1	0.1	0.3	-0.2
Glaucoma (self-reported)	0.0	0.1	0.1	-0.3	-0.1
Gout (self-reported)	0.0	0.0	0.0	0.0	0.1
Eye problems/disorders: None of the above	0.0	0.0	0.0	0.2	0.2
Comparative height size at age 10	0.0	0.3	0.3	0.6	-0.4
Had major operations	0.0	0.0	0.0	-0.1	0.2
Hypertension (Self-reported)	0.0	0.0	0.1	-0.1	0.3
Leg fat-free mass (right)	0.0	0.0	0.0	-0.0	0.1
Ever had bowel cancer screening	0.0	0.0	0.1	-0.2	0.1
Osteoporosis (self-reported)	0.0	0.1	0.1	0.3	-0.0
Osteoarthritis (self-reported)	0.0	0.0	0.0	-0.2	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.0	0.0	-0.1	-0.1
Leg predicted mass (right)	0.0	0.0	0.0	-0.1	0.1
Financial situation satisfaction	0.0	0.0	0.0	0.2	0.1
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.0	-0.1	-0.1
Medication: Lisinopril	0.0	0.1	0.1	0.3	-0.2
Basal metabolic rate	0.0	0.1	0.1	-0.0	-0.4
Arm fat-free mass (left)	0.0	0.2	0.3	-0.2	-0.5
Irritability	0.0	0.0	0.1	-0.0	0.3
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.2	-0.4	-0.2
Heart attack/myocardial infarction (self-reported)	0.0	0.1	0.1	0.3	0.0
Impedance of whole body	0.0	0.1	0.1	-0.3	0.2
Arm predicted mass (left)	0.0	0.2	0.3	-0.1	-0.6

Hub : Genes

LOC113230

Models

Trait associations