TWAS hub - LOC284009

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0162	0.0094	0.00740	0.005	0.007	0.001	NA	0.002	2.3e-02	0.01400	1.6e-01	NA	1.3e-01
2	TCGA	Brain Lower Grade Glioma	0.0551	0.0232	0.00041	0.037	0.025	0.026	NA	0.026	4.2e-05	0.00064	6.0e-04	NA	5.5e-04
3	TCGA	Prostate Adenocarcinoma	0.0420	0.0223	0.00760	0.027	0.009	0.013	NA	0.014	7.4e-04	0.03500	1.3e-02	NA	1.1e-02
4	TCGA	Stomach Adenocarcinoma	0.0910	0.0500	0.00700	-0.004	0.002	-0.003	NA	-0.004	8.3e-01	0.23000	5.7e-01	NA	8.5e-01
5	TCGA	Testicular Germ Cell Tumors	0.1440	0.0740	0.00420	0.104	0.044	0.051	NA	0.075	1.6e-04	0.01100	6.8e-03	NA	1.2e-03
6	TCGA	Thyroid Carcinoma	0.0680	0.0340	0.00082	0.027	0.035	0.046	NA	0.050	1.2e-03	0.00025	2.6e-05	NA	1.2e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
Impedance of leg (left)	6.7	32.5	51.8	-7.2	-5.4	0.8	-7.2	-5.5	-5.5
Alcohol usually taken with meals	6.7	10.9	24.5	3.2	3.4	-0.6	5.0	3.5	2.6
Impedance of leg (right)	6.5	31.6	49.8	-7.0	-5.4	0.5	-7.1	-5.5	-5.6
Serious illness, injury or assault of a close relative in last 2 years	5.3	6.1	7.8	2.8	2.5	2.2	2.6	2.6	2.0
Schizophrenia vs Biploar Disorder	5.2	6.8	9.9	-3.1	-2.8	-0.3	-2.8	-2.8	-2.8
Pack years of smoking	5.0	7.4	15.8	-2.7	-3.0	0.8	-4.0	-3.1	-1.7
Pack years adult smoking proportion	4.3	6.6	14.1	-2.6	-2.7	0.7	-3.8	-2.9	-1.6
Impedance of whole body	4.3	22.0	42.4	-6.5	-4.2	-0.3	-5.9	-4.3	-4.3
Heart disease (mother)	4.1	5.0	9.8	-2.0	-2.1	0.1	-3.1	-2.2	-2.7
Illnesses of father: Heart disease	3.9	5.5	13.6	2.5	1.9	-0.8	3.7	2.0	2.0
Commuting to job workplace: Cycle	3.9	4.7	11.6	2.6	1.9	0.1	3.4	2.1	1.3
Qualifications: None of the above	3.6	7.7	15.8	-3.0	-2.9	-0.0	-4.0	-3.0	-2.0
LDL Cholesterol	3.5	5.5	11.1	-3.3	-2.3	-1.0	-2.3	-2.3	-2.2
Blood Platelet Count	3.5	40.0	87.6	-9.3	-3.9	-1.9	-9.4	-4.1	-5.6
Medication: Gliclazide	3.3	3.7	8.9	1.6	3.0	0.2	-0.4	3.0	1.4
Hearing aid user	3.3	3.7	6.8	-1.5	-2.6	-1.0	-1.4	-2.5	-2.0
Worry too long after embarrassment	3.2	5.4	8.3	-2.4	-2.9	-2.4	-2.4	-2.6	-0.7
Ever smoked	3.2	5.6	10.8	3.3	2.2	1.3	1.6	2.4	2.8
Systolic Blood Pressure	3.0	15.2	23.7	-4.3	-4.0	-0.6	-4.9	-4.2	-3.8
Systolic blood pressure, automated reading	3.0	8.7	15.6	-3.3	-2.9	-0.2	-3.9	-3.2	-2.6
Mood swings	2.9	5.2	8.7	-2.1	-3.0	-1.7	-2.3	-2.9	-1.0
Neuroticism (2016)	2.8	4.0	8.0	-2.0	-2.8	-0.8	-1.7	-2.7	-1.1
Ever used hormone-replacement therapy (HRT)	2.8	3.5	11.0	-0.7	-1.5	1.9	-3.3	-1.6	-1.2
Medication: Metformin	2.8	4.0	8.9	2.0	3.0	0.4	0.6	3.0	1.3
Alzheimer’s Disease (in mother)	2.7	3.2	4.5	1.5	2.0	-0.6	2.0	2.1	1.9
Nervous feelings	2.7	5.1	11.5	-1.5	-2.7	-0.9	-3.4	-2.6	-1.5
Father’s age at death	2.7	3.6	5.7	0.8	2.2	-0.7	2.4	2.3	2.2
Smoking status: Previous	2.7	4.0	9.1	3.0	1.3	1.0	2.3	1.5	2.1
Financial situation satisfaction	2.7	3.4	8.1	1.7	1.3	1.2	2.0	1.4	2.9
Neuroticism (Nagel 2018)	2.6	6.1	11.6	-2.3	-3.4	-2.0	-2.1	-3.2	-1.1
Noisy workplace	2.6	3.2	5.1	-1.2	-1.9	0.6	-2.2	-1.9	-2.3
Supplements: Glucosamine	2.4	3.1	5.1	2.3	2.1	0.6	1.4	2.0	1.7
Knee pain experienced in last month	2.4	3.7	6.8	1.9	2.6	-0.3	0.8	2.6	2.1
Past tobacco smoking	2.3	4.3	10.2	-3.2	-1.6	-1.4	-1.6	-1.7	-2.3
Length of working week for main job	2.3	2.6	4.9	-0.7	-2.1	0.9	-0.6	-2.1	-2.2
Leg fat-free mass (right)	2.3	12.1	20.2	4.5	3.7	0.4	3.7	3.6	3.5
Leg predicted mass (right)	2.3	12.4	20.4	4.5	3.7	0.3	3.7	3.7	3.6
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	4.7	-1.6	-2.1	-0.3	-1.1	-2.2	-1.8
Eye problems/disorders: Diabetes related eye disease	2.1	2.3	4.7	2.2	1.2	2.0	1.0	1.2	1.0
Wheeze or whistling in the chest in last year	2.1	3.7	6.0	2.4	2.2	-0.1	1.9	2.3	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.1	2.5	4.9	-1.4	-1.9	-0.1	-1.2	-1.8	-2.2
Alcohol drinker status: Never	2.1	2.5	7.4	-1.8	-0.8	-0.3	-2.7	-1.0	-1.6
Hayfever, allergic rhinitis or eczema	2.0	4.4	9.1	1.6	2.1	-1.4	3.0	2.4	1.4
Hair/balding pattern: Pattern 2	2.0	2.5	4.8	-1.8	-1.6	-2.2	-0.6	-1.4	-1.4
Impedance of arm (left)	2.0	9.3	23.4	-4.8	-2.2	-0.9	-3.9	-2.4	-2.3
Birth weight	2.0	4.4	11.7	-2.5	-1.5	-0.2	-3.4	-1.8	-1.7
Depressed Affect (Nagel 2018)	1.9	4.0	8.4	-2.2	-2.9	-1.0	-1.2	-2.8	-0.5
Leg fat-free mass (left)	1.9	10.1	18.0	4.2	3.4	0.3	3.2	3.3	3.2
Maternal smoking around birth	1.9	2.7	4.0	1.8	1.9	2.0	-0.3	1.9	1.4
Diabetes (self-reported)	1.9	2.9	5.8	1.9	2.4	0.2	1.1	2.4	1.2
Guilty feelings	1.9	2.9	5.3	-0.8	-2.3	-2.0	-0.9	-2.1	-1.5
Fractured/broken bones in last 5 years	1.9	2.5	4.6	1.3	2.1	0.4	1.0	2.2	1.7
Age started oral contraceptive pill	1.9	2.3	6.3	-2.1	-0.7	-0.9	-2.5	-0.8	-1.2
Average weekly spirits intake	1.8	2.3	3.4	1.4	1.8	1.2	0.2	1.8	1.8
Relative age of first facial hair	1.8	3.6	5.2	-2.0	-2.1	1.2	-2.3	-2.2	-1.3
Leg predicted mass (left)	1.8	9.8	17.4	4.2	3.3	0.2	3.3	3.2	3.1
Loud music exposure frequency	1.8	2.0	3.9	-1.6	-1.5	-0.3	-2.0	-1.5	-0.9
Mouth/teeth dental problems: Bleeding gums	1.8	2.4	4.1	1.8	2.0	-0.7	1.0	2.0	1.2
Leg fat percentage (right)	1.8	6.7	20.9	-1.6	-2.3	-0.8	-4.6	-2.3	-2.3
Medication: Seretide 50 evohaler	1.8	2.0	3.0	-0.6	-1.6	0.8	-1.7	-1.7	-1.7
Whole body fat-free mass	1.8	10.2	19.1	4.4	3.1	1.1	3.6	3.1	3.0
Qualifications: nursing, teaching	1.8	2.8	5.6	1.8	2.2	-1.1	1.1	2.4	0.4
Whole body water mass	1.8	10.0	18.9	4.3	3.1	1.1	3.5	3.1	2.9
Heart attack	1.7	2.2	4.4	2.1	1.4	-0.3	1.5	1.5	1.4
Allergy	1.7	4.0	7.6	-1.6	-2.3	0.5	-2.8	-2.5	-1.4
Medication: Simvastatin	1.7	2.6	4.7	-1.4	-1.7	-1.1	-1.5	-1.6	-2.2
Impedance of arm (right)	1.7	8.1	19.8	-4.5	-2.3	-0.8	-3.7	-2.4	-2.0
Trunk fat-free mass	1.7	9.9	18.6	4.3	2.9	1.3	3.8	2.9	2.9
Medication: Lansoprazole	1.7	1.9	3.7	0.7	1.3	-1.9	0.7	1.4	1.8
Trunk predicted mass	1.7	9.4	18.0	4.2	2.8	1.4	3.6	2.8	2.8
Back pain experienced in last month	1.7	2.5	9.0	1.8	1.0	3.0	-0.1	1.0	0.9
Illnesses of father: None of the above (group 1)	1.7	2.1	3.1	-1.8	-1.6	0.1	-1.7	-1.6	-1.3
Heart disease (siblings)	1.7	2.1	6.6	1.0	1.3	-0.9	2.6	1.4	0.6
Smoking Status	1.6	3.9	7.8	2.8	1.5	1.6	1.6	1.8	2.3
Neuroticism	1.6	3.8	7.5	-2.0	-2.7	-1.3	-1.8	-2.5	-0.7
Diverticular disease/diverticulitis (self-reported)	1.6	1.9	5.3	-0.5	-0.7	1.5	-2.3	-0.9	-1.5
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.6	5.9	-1.6	-2.4	-0.5	-1.3	-2.2	-0.1
Commuting to job workplace: Walk	1.6	1.8	5.5	-2.4	-0.5	-1.2	-1.7	-0.4	-0.7
Osteoarthritis (self-reported)	1.6	2.0	3.2	1.8	1.0	1.5	1.6	1.0	1.4
Commuting to job workplace: Public transport	1.6	2.0	3.0	0.7	1.6	-0.5	1.6	1.7	1.6
Illnesses of father: High blood pressure	1.6	2.0	4.1	-0.7	-2.0	-1.7	0.5	-2.0	-0.5
Leg fat percentage (left)	1.6	5.8	19.3	-1.5	-2.1	-0.7	-4.4	-2.1	-2.0
Average weekly fortified wine intake	1.5	1.8	3.4	0.1	1.8	-0.4	1.8	1.8	0.8
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.5	9.0	2.2	1.0	1.0	3.0	1.1	2.0
Age at last live birth	1.5	2.2	2.7	1.2	1.6	1.4	1.6	1.5	1.4
Average weekly red wine intake	1.5	2.2	5.8	2.4	1.2	-0.2	1.9	1.2	0.8
Alzheimer’s Disease (including proxy)	1.4	2.1	4.1	1.1	2.0	-0.1	1.2	2.0	1.3
Schizophrenia (2014)	1.4	3.2	6.6	-2.6	-1.9	-0.5	-1.0	-1.8	-2.1
Financial difficulties in last 2 years	1.4	1.8	4.9	-2.2	-1.4	-0.6	-1.2	-1.3	-0.8
Qualifications: College or University degree	1.3	4.2	6.7	2.1	2.6	-0.5	2.5	2.6	1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	5.7	1.4	0.3	2.4	0.6	0.4	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.6	4.9	2.2	0.7	0.9	0.9	0.8	1.3
Basal metabolic rate	1.3	7.3	14.9	3.9	2.7	0.8	2.7	2.6	2.6
Worry (Nagel 2018)	1.2	2.6	5.7	-1.4	-1.7	-2.4	-1.6	-1.5	-0.4
HbA1C	1.2	1.4	3.0	1.2	1.2	1.7	-0.0	1.2	0.7
Heel T-Score	1.2	9.8	30.0	5.5	1.0	2.8	4.2	1.1	1.0
Lung FEV1/FVC ratio	1.2	5.9	9.6	-3.0	-1.8	-1.9	-2.7	-1.7	-3.1
Medication for hormone replacement therapy	1.2	1.4	2.5	-1.3	-1.3	0.3	-1.6	-1.3	-0.8
Mouth/teeth dental problems	1.2	1.9	3.3	-1.8	-1.5	0.9	-0.8	-1.6	-1.2
Number of live births	1.2	1.7	2.9	1.7	1.2	0.7	1.5	1.3	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	4.6	2.1	1.0	-0.1	1.3	1.2	1.6
Blood clot in the leg (DVT)	1.2	1.6	3.2	1.1	1.4	1.8	1.1	1.4	0.3
Body fat percentage	1.2	4.8	16.8	-1.6	-1.7	-1.1	-4.1	-1.8	-1.6
Health satisfaction	1.2	1.6	5.2	0.5	0.8	-0.5	1.5	1.0	2.3
Pulse rate, automated reading	1.2	3.9	9.4	-1.8	-2.0	0.4	-3.1	-2.2	-1.3
Supplements: Vitamin C	1.2	1.4	4.2	1.6	0.7	-0.4	2.0	0.9	0.6
Average weekly champagne plus white wine intake	1.2	1.6	5.6	0.6	1.1	-0.1	2.4	1.1	1.2
Myopia	1.2	1.7	3.6	0.1	1.3	-1.9	1.4	1.4	1.1
Ulcerative Colitis	1.1	1.5	7.1	1.1	-0.2	0.9	2.7	-0.0	-0.4
Ever had hysterectomy (womb removed)	1.1	1.2	2.3	-0.4	-1.4	0.4	-1.1	-1.3	-1.5
Medication: Ramipril	1.1	1.4	2.8	0.9	1.1	0.8	1.7	1.1	1.3
Medication: Cholesterol lowering	1.1	1.7	3.3	-0.9	-1.5	0.1	-1.2	-1.4	-1.8
Prospective memory result	1.1	1.3	1.8	-1.3	-1.2	-0.8	-0.9	-1.3	-1.3
Tense / ‘highly strung’	1.1	1.9	6.8	-1.3	-0.8	-2.6	-1.1	-0.7	-0.6
Arm fat-free mass (right)	1.1	5.5	11.7	3.4	2.2	1.1	2.6	2.2	1.8
Alcohol intake frequency.	1.1	2.5	8.6	-1.5	-0.9	1.2	-2.9	-0.9	-0.7
Asthma (self-reported)	1.1	2.2	4.8	1.5	1.5	0.6	2.2	1.6	1.1
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	2.3	1.0	1.4	1.5	1.1	1.4	0.2
Bipolar Disorder (2018)	1.0	1.6	2.8	0.7	1.6	-0.1	1.4	1.7	1.3
Alzheimer’s Disease (in father)	1.0	1.1	2.4	0.3	1.6	1.4	-0.2	1.4	0.6
Allergy or Eczema	1.0	2.5	4.8	0.9	1.7	-1.4	2.2	1.9	0.9
Type 2 Diabetes (T2D) (2018)	1.0	1.8	3.9	1.6	2.0	0.9	0.0	1.9	0.1
Trunk fat percentage	1.0	4.1	14.2	-1.7	-1.5	-1.1	-3.8	-1.6	-1.4
Multivitamins +/- minerals	1.0	1.3	2.4	1.3	1.5	-0.3	0.1	1.6	1.2
Alcohol intake versus 10 years previously	1.0	1.4	4.2	1.4	1.1	2.1	0.6	0.9	0.3
Happiness	1.0	1.3	3.0	-1.1	-1.4	-1.7	0.2	-1.1	0.2
Exposure to tobacco smoke at home	1.0	1.1	2.1	-0.9	-1.5	1.0	-0.9	-1.4	-0.4
Breastfed as a baby	1.0	1.3	3.0	1.7	1.1	0.5	0.9	1.0	1.2
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	2.2	1.2	1.5	1.1	1.2	1.4	1.3
Arm predicted mass (right)	1.0	5.2	12.5	3.5	2.2	0.9	2.3	2.2	1.7
Diabetes diagnosed by doctor	1.0	1.7	3.9	1.4	1.9	0.5	0.5	2.0	0.5
Supplements: Fish oil (including cod liver oil)	1.0	1.4	3.0	-1.0	-1.1	-0.5	-1.7	-1.1	-1.2
Heart attack/myocardial infarction (self-reported)	1.0	1.3	3.0	1.7	1.0	-0.2	1.2	1.1	1.0
Arm predicted mass (left)	1.0	5.3	12.5	3.5	2.3	1.1	2.2	2.2	1.8
Lupus	0.9	1.4	3.0	-1.7	-1.3	-0.5	-0.7	-1.3	-1.3
Taking other prescription medications	0.9	1.4	2.3	-1.2	-1.2	-0.7	-1.5	-1.1	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	4.3	2.0	0.5	0.5	2.1	0.7	1.6
Neuroticism score	0.9	1.8	3.6	-1.0	-1.7	-1.1	-1.9	-1.5	0.3
Worrier / anxious feelings	0.9	1.7	4.6	0.3	0.6	-2.1	-0.8	0.7	2.1
Asthma	0.9	1.8	4.2	1.4	1.2	0.3	2.1	1.3	1.0
Emphysema/chronic bronchitis	0.9	1.0	1.5	-1.1	-1.2	0.9	-0.5	-1.2	-0.8
Family relationship satisfaction	0.9	1.2	3.6	-0.9	-1.2	-1.9	0.1	-1.0	-0.2
Commuting to job workplace: Car/motor vehicle	0.9	1.0	2.8	-0.6	-1.0	-0.4	-1.7	-1.2	-0.6
Arm fat-free mass (left)	0.9	4.3	11.0	3.3	1.9	1.2	2.0	1.8	1.6
Diastolic blood pressure, automated reading	0.9	2.8	5.1	-1.4	-1.9	-0.6	-2.3	-2.1	-1.2
Ulcerative Colitis (UC)	0.8	1.6	4.7	1.8	0.4	0.8	2.2	0.5	0.7
Breast Cancer	0.8	1.9	5.0	-0.3	-1.5	-0.3	-2.2	-1.6	-1.1
Primary Biliary Cirrhosis	0.8	1.1	3.9	0.3	-0.4	-2.0	1.6	-0.2	-0.2
Angina	0.8	1.0	3.1	0.3	-0.9	-0.0	-1.1	-0.9	-1.7
Chronic bronchitis/emphysema (father)	0.8	1.0	1.7	0.4	1.3	0.9	0.5	1.3	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	4.4	-0.7	-0.9	-2.1	-0.8	-0.8	0.4
Pulse wave reflection index	0.8	1.0	1.7	-1.3	-1.3	-0.7	-0.1	-1.2	-1.0
Medication: Ventolin 100micrograms inhaler	0.8	1.1	2.9	-0.7	-1.1	-0.8	0.3	-1.0	-1.7
Medication: Allopurinol	0.8	1.0	1.6	0.7	0.9	-1.3	1.1	1.0	1.0
Overall health rating	0.8	1.7	2.8	-1.6	-1.3	-1.7	-1.4	-1.1	-0.0
Medication: Atorvastatin	0.8	1.0	1.6	-1.1	-0.9	0.0	-1.3	-0.9	-1.3
Unable to work because of sickness or disability	0.8	1.0	5.7	-0.6	-0.1	-0.2	-2.4	-0.2	0.2
HDL Cholesterol	0.7	1.1	3.4	-1.9	-1.1	-0.8	-0.7	-1.0	-0.3
Rheumatoid Arthritis	0.7	1.0	2.8	-1.7	-1.0	-0.8	-0.5	-1.1	-0.3
Number of treatments/medications taken	0.7	1.3	2.1	-1.0	-1.4	-0.8	-1.2	-1.4	-0.7
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.8	1.3	0.8	-0.8	0.7	0.8	0.3
Hearing difficulty/problems with background noise	0.7	1.1	4.2	0.5	-1.2	-2.1	0.6	-0.8	0.1
Hair/balding pattern: Pattern 3	0.7	1.0	1.8	-1.3	-1.3	0.3	-0.7	-1.3	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.8	3.2	-1.8	-0.4	-0.1	-1.1	-0.5	-0.5
Ever highly irritable/argumentative for 2 days	0.7	0.9	2.9	0.3	0.0	-1.7	1.0	0.3	1.1
Number of full brothers	0.7	0.9	3.5	-0.1	-0.2	1.9	-1.3	-0.1	-0.1
Angina (self-reported)	0.7	0.9	2.8	0.5	-0.7	-0.1	-1.1	-0.7	-1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	1.8	1.1	0.5	1.2	-1.3	0.4	0.5
Breast cancer (self-reported)	0.7	0.8	1.9	-0.8	-0.7	0.2	-1.4	-0.8	-1.0
Smoking status: Current	0.7	1.2	1.8	1.1	1.1	1.3	-0.6	1.2	1.0
Ever depressed for a whole week	0.7	0.8	1.7	1.3	0.5	-0.2	0.9	0.7	1.2
Pain experienced in last month	0.7	1.2	2.8	-1.7	-0.8	-0.9	-0.8	-0.9	-1.2
Schizophrenia (2018)	0.6	1.2	3.5	-1.9	-1.0	0.1	-0.5	-1.0	-1.3
Crohns Disease (2012)	0.6	1.0	1.5	-1.0	-1.2	-0.5	0.5	-1.1	-1.2
Triglycerides	0.6	1.1	1.4	-1.2	-1.1	-0.4	-0.9	-1.2	-1.1
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.2	1.5	0.8	0.8	0.1	0.7	0.3
Hand grip strength (left)	0.6	1.7	6.5	1.4	-0.0	2.5	1.0	-0.2	0.7
Sensitivity / hurt feelings	0.6	1.1	2.7	-0.5	-1.7	-0.3	-1.1	-1.5	0.1
Hearing difficulty/problems: Yes	0.6	0.9	3.0	-0.4	-1.7	-0.4	-0.3	-1.5	0.2
Townsend deprivation index at recruitment	0.6	0.8	1.5	0.7	1.1	-0.6	-0.6	1.2	1.0
Age when periods started (menarche)	0.6	1.4	2.7	-1.6	-1.3	-0.6	-1.0	-1.2	-0.9
Pain all over the body in last month	0.6	0.6	1.5	-1.2	-0.6	0.2	-0.9	-0.7	-0.6
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.5	0.8	0.6	-0.6	1.6	0.8	0.4
Illnesses of siblings	0.6	0.8	1.4	-0.7	-1.2	0.6	-0.8	-1.2	-0.9
Hair/balding pattern: Pattern 4	0.6	1.5	7.2	-1.3	-0.2	-0.0	-2.7	-0.3	-0.4
Comparative body size at age 10	0.6	1.6	6.2	0.8	1.1	-2.5	0.1	1.0	0.8
Number of children fathered	0.6	0.7	1.9	1.3	0.4	1.4	0.5	0.4	0.4
Shortness of breath walking on level ground	0.6	0.7	1.6	0.9	0.4	1.1	0.6	0.5	1.2
Migraine (self-reported)	0.6	0.8	1.9	-1.1	-0.8	0.1	-1.4	-0.9	-0.4
Had major operations	0.6	0.7	1.4	0.8	-0.8	-1.2	-0.2	-0.8	-0.8
Leg pain on walking	0.6	0.7	1.2	-0.8	-0.4	1.1	-1.1	-0.5	-1.1
Ever had bowel cancer screening	0.6	0.7	2.1	-0.9	-0.5	-1.4	0.6	-0.6	-0.3
Miserableness	0.6	1.0	3.1	-0.3	-1.8	-0.4	-0.3	-1.6	0.5
Ever taken oral contraceptive pill	0.6	0.6	1.2	0.2	1.0	0.8	0.3	1.1	0.9
Medication: Blood pressure	0.6	1.1	3.8	1.0	0.5	0.2	1.9	0.5	1.0
Risk taking	0.6	0.9	1.5	1.2	0.9	0.8	1.2	1.0	0.1
Irritable Bowel Disease (IBD)	0.5	1.2	3.8	1.1	-0.0	1.4	1.9	0.1	0.5
Prostate Cancer	0.5	0.7	2.2	-0.6	-0.4	1.5	-0.1	-0.5	-1.0
Age at First Birth	0.5	0.7	1.4	0.9	1.2	0.7	-0.5	1.1	-0.1
Coronary Artery Disease (CAD)	0.5	0.6	1.2	1.1	0.4	0.7	0.6	0.4	1.1
Fasting Glucose	0.5	0.5	1.5	-0.8	-0.5	0.2	-0.8	-0.5	-1.2
Chronotype (morning person)	0.5	1.2	2.1	0.1	-1.1	1.4	-1.4	-1.1	-0.9
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.8	0.1	-0.6	0.5	-1.3	-0.6	-0.9
Severe depression (siblings)	0.5	0.5	1.8	0.2	-0.3	-1.3	0.9	-0.2	-0.6
Current tobacco smoking	0.5	0.9	1.4	0.9	1.0	0.9	-0.5	1.2	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	3.6	0.1	-0.4	0.5	-1.9	-0.5	-0.1
Waist circumference	0.5	1.7	4.2	2.1	1.0	-1.6	0.1	1.1	1.0
Time employed in main current job	0.5	0.6	3.1	0.4	-0.1	1.8	-0.1	-0.2	0.0
Falls in the last year	0.5	0.7	1.1	-0.2	1.0	-0.8	-0.5	1.1	1.0
Pulse wave Arterial Stiffness index	0.5	0.5	1.0	-0.9	-0.7	-1.0	-0.6	-0.7	-0.5
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.6	0.1	1.0	0.3	1.1	1.0	1.2
Age at first live birth	0.5	0.9	3.3	0.6	0.8	0.6	1.8	0.6	0.8
Medication for pain relief, constipation, heartburn	0.5	0.8	1.3	0.8	1.0	-1.2	0.8	1.0	0.4
Comparative height size at age 10	0.5	2.8	6.5	1.4	1.7	2.5	1.5	1.5	1.1
Friendships satisfaction	0.5	0.6	1.3	-0.5	-1.0	-1.1	0.9	-0.7	-0.2
Wears glasses or contact lenses	0.5	0.6	1.1	-0.4	-1.1	-0.9	0.1	-1.0	-0.8
Pain type(s) experienced in last month: Hip pain	0.5	0.7	1.4	-0.6	-1.2	0.6	-0.4	-1.2	-0.4
Number of operations (self-reported)	0.5	0.8	2.0	1.4	-0.9	0.1	-0.5	-0.9	-1.0
Mean Putamen Volume	0.4	0.5	0.8	-0.2	0.8	-0.5	0.7	0.9	0.9
Blood Eosinophil Count	0.4	2.8	4.8	2.2	2.0	1.1	1.1	1.8	1.5
Blood White Count	0.4	3.2	10.4	-2.2	0.6	1.5	-3.2	0.4	-0.9
BMI	0.4	2.3	6.7	2.6	1.5	-0.6	-0.0	1.5	1.5
Diabetes (father)	0.4	0.4	1.1	-0.8	-0.6	-0.2	-0.4	-0.6	-1.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.1	1.0	0.4	0.1	-1.0	0.5	-0.2
Had menopause	0.4	0.4	1.4	-0.5	-0.3	0.0	-1.2	-0.4	-0.9
Had other major operations	0.4	0.5	1.7	1.3	0.5	0.5	0.8	0.6	0.2
Forced vital capacity (FVC)	0.4	1.7	8.3	0.6	0.8	2.9	0.2	0.5	0.7
Pulse rate	0.4	0.7	2.5	-0.8	-0.1	1.6	-1.1	-0.2	-0.0
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.8	0.5	0.6	0.5	1.7	0.7	0.8
Medication: Paracetamol	0.4	0.7	2.1	-0.6	-0.8	1.4	-0.8	-0.8	0.3
Glaucoma (self-reported)	0.4	0.4	1.0	-0.7	-1.0	-0.3	-0.3	-0.9	-0.4
Exposure to tobacco smoke outside home	0.4	0.6	1.7	-1.3	0.3	-0.4	-1.2	0.3	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.2	-1.1	-0.0	-0.9	-0.4	-0.0	-0.7
Pulse wave peak to peak time	0.4	0.5	1.2	0.8	0.6	1.1	0.6	0.6	0.4
Neck or shoulder pain in last month	0.4	0.5	1.4	0.8	-0.7	1.2	-0.4	-0.6	0.4
Medication: Blood pressure	0.4	0.7	1.7	-1.0	-0.7	-1.3	-0.6	-0.7	-0.4
Suffer from ‘nerves’	0.4	0.7	2.0	-0.0	0.5	-0.3	-1.4	0.5	1.2
Mineral and other dietary supplements	0.4	0.5	1.8	0.8	0.4	0.5	1.4	0.4	0.4
Number of self-reported non-cancer illnesses	0.4	0.7	1.5	0.9	0.5	-0.5	1.2	0.7	0.9
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.0	0.3	-1.0	0.6	-0.4	-0.9	-0.3
Eye problems/disorders: Glaucoma	0.4	0.5	1.3	-0.2	-1.1	0.3	-0.0	-1.0	-0.6
Supplements: Calcium	0.4	0.5	1.0	0.6	1.0	0.7	-0.4	1.0	0.2
Depression (Nagel 2018)	0.3	0.5	1.1	-0.6	-0.7	-0.6	-1.1	-0.7	-0.2
Reaction Time	0.3	0.7	1.9	0.1	1.4	-0.6	-0.1	1.3	0.3
Ovarian Cancer	0.3	0.4	1.2	0.2	-0.0	-0.9	1.1	0.1	0.4
Waist Hip Ratio (WHR)	0.3	1.6	7.1	0.6	0.8	-2.7	0.6	0.8	-0.5
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.8	0.4	0.1	-0.7	-0.9	0.2	0.9
Medication: Co-codamol	0.3	0.4	1.3	-0.1	0.6	1.1	0.1	0.7	0.4
Hand grip strength (right)	0.3	0.8	1.9	-0.2	-1.1	1.4	0.4	-1.2	-0.4
Fed-up feelings	0.3	0.5	1.3	-0.5	-1.1	-0.5	-0.3	-1.0	0.5
Serious illness, injury or assault to yourself	0.3	0.3	1.3	0.2	-0.2	-0.5	-1.1	-0.3	-0.6
Medication: Atenolol	0.3	0.3	0.7	0.5	-0.8	0.4	0.6	-0.7	0.3
High blood pressure (mother)	0.3	0.4	1.3	-0.3	0.5	1.1	-0.5	0.5	-0.3
Body mass index (BMI)	0.3	1.3	5.2	2.3	0.8	-0.9	-0.1	0.8	1.0
Trunk fat mass	0.3	1.1	5.7	-0.2	-0.4	-0.8	-2.4	-0.5	-0.4
Weight	0.3	1.6	5.0	2.2	1.2	-0.3	0.3	1.2	1.2
Arm fat percentage (right)	0.3	1.0	3.7	0.5	-0.0	-1.4	-1.9	-0.1	0.3
Mouth/teeth dental problems: Dentures	0.3	0.6	2.1	-0.0	-0.7	-0.1	-1.5	-0.7	-0.7
Illnesses of mother	0.3	0.3	1.2	-0.0	-0.7	-1.1	0.1	-0.6	-0.2
Peak expiratory flow (PEF)	0.3	0.6	2.9	-0.3	-0.1	1.7	-0.7	-0.2	0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.3	0.3	-0.7	-1.2	-0.1	-0.6	-0.4
Medication: Ibuprofen	0.3	0.3	1.5	-1.2	-0.2	0.0	-0.5	-0.4	-0.2
Mean time to correctly identify matches	0.3	0.6	1.6	-0.1	1.3	-0.5	-0.2	1.2	0.2
Whole body fat mass	0.3	1.1	5.1	0.1	-0.4	-0.8	-2.3	-0.5	-0.5
Leg fat mass (right)	0.3	1.3	5.7	0.3	-0.8	-0.7	-2.4	-0.8	-0.7
Number of full sisters	0.3	0.4	1.3	0.1	-1.1	-0.3	0.1	-1.0	-0.4
Chest pain or discomfort	0.3	0.4	1.0	-0.3	-0.3	-0.9	1.0	-0.2	-0.6
Medication: Aspirin	0.3	0.4	2.2	0.6	-0.1	1.5	0.2	-0.2	0.1
Hypertension (Self-reported)	0.3	0.7	1.7	-0.9	-0.9	-1.3	-0.5	-0.8	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.4	0.1	0.3	1.5	-1.2	0.2	-0.1
Loneliness, isolation	0.3	0.4	0.9	-0.4	-0.1	0.8	-1.0	-0.1	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	1.2	-0.7	-1.1	0.6	0.9	-1.1	-0.3
Mother’s age at death	0.3	0.3	1.0	-0.5	0.2	0.2	-1.0	0.1	-0.8
Average weekly beer plus cider intake	0.3	0.4	2.1	0.1	-0.0	0.3	-1.5	0.0	0.4
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.5	0.5	-0.2	-0.0	1.2	-0.2	0.6
Basal cell carcinoma (self-reported)	0.3	0.3	1.0	-0.8	-0.1	0.2	-1.0	-0.1	-0.5
Alcohol drinker status: Previous	0.3	0.3	1.2	-0.2	-0.7	1.1	0.0	-0.5	0.0
Leg fat mass (left)	0.3	1.3	5.8	0.2	-0.7	-0.6	-2.4	-0.7	-0.6
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.6	0.8	1.2	0.8	0.2	1.1	0.3
Major Depression (MDD)	0.2	0.3	0.5	0.7	-0.4	-0.5	-0.1	-0.3	-0.7
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.6	-0.4	0.6	-1.3	-0.3	0.6	0.0
Body Mass Index (BMI) (2010)	0.2	0.2	0.6	0.6	0.1	-0.5	0.3	0.1	0.8
Blood Red Count	0.2	1.5	5.2	1.8	0.4	-0.4	2.3	0.4	0.2
Cardiovascular Disease	0.2	0.5	1.1	-0.1	-1.0	-0.8	-0.8	-0.9	-0.1
Respiratory disease	0.2	0.5	1.2	0.3	0.8	0.4	1.1	0.8	0.2
Lung FVC	0.2	0.8	4.4	-0.3	-0.2	2.1	-0.4	-0.4	-0.3
Supplements: Zinc	0.2	0.2	0.9	0.2	0.1	0.6	0.9	0.1	0.3
Relative age voice broke	0.2	0.3	0.9	-0.9	-0.6	-0.2	-0.7	-0.6	-0.0
Medication: Levothyroxine sodium	0.2	0.3	0.8	-0.1	0.7	0.9	-0.4	0.7	0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.8	-0.3	-0.2	-0.7	0.3	-0.2	0.9
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	3.3	-0.4	-0.1	1.8	-0.5	-0.3	-0.5
Arm fat mass (right)	0.2	0.8	2.2	1.5	0.6	-0.9	-0.8	0.6	0.8
Birth weight of first child	0.2	0.4	1.1	-0.8	-0.3	0.7	-1.1	-0.4	-0.1
Headache pain in last month	0.2	0.4	1.8	-0.3	0.1	0.4	-1.3	0.0	0.4
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.6	0.3	-0.2	-0.5	-0.8	-0.1	0.2
High blood pressure (siblings)	0.2	0.2	0.7	0.2	0.4	0.5	-0.3	0.4	0.8
Forced vital capacity (FVC), Best measure	0.2	0.7	3.8	0.0	-0.2	1.9	0.5	-0.3	-0.1
Eye problems/disorders: None of the above	0.2	0.2	0.4	-0.5	-0.3	-0.4	-0.7	-0.5	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.9	0.3	-0.0	0.9	-0.1	-0.0	0.6
Arm fat percentage (left)	0.2	1.0	4.2	0.4	-0.0	-1.2	-2.0	-0.1	0.2
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.9	-0.4	0.2	0.9	-0.6	0.1	-0.5
Long-standing illness, disability or infirmity	0.2	0.3	1.2	-0.6	-0.2	-0.3	-1.1	-0.2	0.0
Eye problems/disorders: Cataract	0.2	0.2	0.7	-0.1	-0.4	0.5	-0.0	-0.4	-0.8
Medication for cholesterol	0.2	0.2	1.0	-0.4	-0.0	-0.5	-0.3	-0.1	-1.0
Medication: Aspirin	0.2	0.3	0.8	0.7	-0.3	0.9	0.5	-0.4	-0.1
Arm fat mass (left)	0.2	0.8	2.2	1.5	0.6	-0.7	-0.9	0.6	0.6
High cholesterol (Self-reported)	0.2	0.3	0.6	-0.1	-0.5	0.3	-0.8	-0.5	-0.8
Medication: Bendroflumethiazide	0.2	0.3	0.5	-0.6	0.6	0.7	-0.2	0.5	0.5
Medication: Lisinopril	0.2	0.2	0.6	-0.2	-0.3	-0.7	0.7	-0.1	0.4
Bipolar Disorder or Schizophrenia	0.1	0.2	1.0	-1.0	0.3	-0.0	0.5	0.3	-0.2
Crohns Disease (2017)	0.1	0.3	1.1	0.3	0.1	1.0	0.7	0.1	0.1
Height	0.1	1.0	5.1	-0.1	0.1	2.2	-0.8	-0.1	0.4
Hypothyroidism (self reported)	0.1	0.3	0.5	-0.5	0.6	0.4	0.5	0.5	0.7
Tanning	0.1	1.7	6.7	-1.0	-0.8	0.5	-2.6	-1.0	-0.6
Vitamin and mineral supplements	0.1	0.1	0.3	-0.4	-0.5	0.3	-0.0	-0.6	-0.2
Qualifications: CSEs or equivalent	0.1	0.2	0.6	-0.6	-0.0	0.1	-0.8	-0.0	0.1
High blood pressure	0.1	0.4	0.7	-0.7	-0.8	-0.5	-0.2	-0.8	0.1
Stomach or abdominal pain in last month	0.1	0.1	0.3	0.0	-0.3	-0.1	0.5	-0.3	-0.3
Sitting height	0.1	0.8	2.9	-0.9	-0.4	1.7	-0.6	-0.6	-0.5
Number of incorrect matches in round	0.1	0.1	0.3	-0.1	0.3	0.6	-0.1	0.4	-0.1
Fluid intelligence score	0.1	0.3	1.3	-0.4	0.1	-1.1	-0.1	0.1	-0.5
Hip circumference	0.1	0.5	1.6	1.3	0.5	-0.4	-0.3	0.5	0.9
Depression (self-reported)	0.1	0.1	0.2	0.1	0.4	-0.3	-0.1	0.5	0.3
Lung cancer (father)	0.1	0.1	0.6	-0.2	-0.1	-0.8	-0.3	-0.1	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.3	-0.6	-0.4	1.2	0.1	-0.5	-0.7
Standing height	0.1	0.6	1.0	0.1	1.0	1.0	0.8	0.8	0.5
Gout (self-reported)	0.1	0.1	0.4	0.4	0.2	-0.6	0.3	0.2	0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.7	-0.9	0.3	0.2	-0.3	0.3	0.4
Medication: Amlodipine	0.1	0.2	0.5	-0.7	-0.2	-0.3	-0.5	-0.3	0.0
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.5	0.2	0.2	-0.7	-0.3	0.2	-0.0
Medication: Omeprazole	0.1	0.2	0.6	0.8	0.2	0.2	-0.4	0.3	-0.1
Illnesses of siblings: Diabetes	0.1	0.2	0.3	-0.3	0.5	-0.5	0.2	0.5	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.7	-0.2	0.0	-0.7	0.4	0.2	-0.8
Osteoporosis (self-reported)	0.1	0.2	0.6	0.2	-0.2	-0.1	-0.4	-0.1	-0.8
Medication: Paracetamol	0.1	0.2	0.9	-0.3	-0.4	0.3	-1.0	-0.3	0.0
Irritability	0.1	0.2	0.3	0.1	-0.5	0.5	-0.6	-0.5	0.0
Cholesterol lowering medication	0.1	0.2	0.4	0.6	0.1	0.6	-0.6	0.1	0.2
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.5	0.6	-0.3	-0.7	-0.5	-0.1	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	1.4	4.4	1.1	0.8	0.2	2.1	0.7	1.1
Diabetes (mother)	0.0	0.0	0.1	0.2	-0.0	-0.4	-0.0	-0.1	-0.1
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.3	0.1	0.4	0.5	-0.0	0.4	-0.2

Hub : Genes

LOC284009

Models

Trait associations