TWAS hub - LOC339524

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Lung Adenocarcinoma	0.0238	0.0130	0.0028	-0.001	0.016	0.001	NA	0.004	0.40000	0.0047	0.2200	NA	0.1000
2	TCGA	Lung Squamous Cell Carcinoma	0.0241	0.0126	0.0017	0.025	0.023	0.010	NA	0.021	0.00062	0.0012	0.0240	NA	0.0017
3	TCGA	Prostate Adenocarcinoma	0.0429	0.0216	0.0018	0.017	0.023	0.028	NA	0.024	0.00560	0.0018	0.0006	NA	0.0015

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Pulse rate	8.9	15.0	23.0	-4.8	-4.0	-2.5
Illnesses of mother	5.7	7.1	7.6	-2.6	-2.8	-2.6
Osteoporosis (self-reported)	5.3	6.5	7.5	-2.5	-2.7	-2.4
Pulse wave reflection index	5.2	6.5	7.9	2.8	2.3	2.5
Pulse rate, automated reading	5.1	16.5	28.3	-5.3	-4.1	-2.0
Neck or shoulder pain in last month	5.0	7.1	12.7	3.6	2.6	1.3
Medication: Aspirin	5.0	6.5	11.2	1.7	2.3	3.4
Supplements: Zinc	4.9	5.3	7.6	2.8	2.2	1.8
Neuroticism (Nagel 2018)	4.4	10.3	11.4	2.9	3.4	3.3
Medication: Gliclazide	4.1	4.6	6.8	2.4	2.6	1.2
Depressed Affect (Nagel 2018)	4.0	8.4	10.8	3.3	3.0	2.4
HbA1C	4.0	4.4	6.6	2.6	1.8	1.8
Neuroticism	3.9	9.4	12.2	3.2	3.5	2.4
Fractured/broken bones in last 5 years	3.9	5.1	8.1	-2.6	-2.9	-0.5
Medication: Allopurinol	3.8	5.1	6.9	2.6	2.6	1.3
Medication for hormone replacement therapy	3.5	3.9	5.7	1.7	1.8	2.4
Suffer from ‘nerves’	3.4	5.3	6.8	2.5	2.6	1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.4	4.0	6.8	2.3	2.6	0.0
Average weekly fortified wine intake	3.3	3.8	5.0	-2.2	-1.9	-1.6
Maternal smoking around birth	3.3	4.8	7.6	2.8	2.5	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	3.3	4.3	5.2	-1.9	-2.0	-2.3
Illnesses of father: High blood pressure	3.3	4.0	5.1	2.3	2.2	1.5
Hearing difficulty/problems with background noise	3.2	5.2	9.6	2.1	3.1	1.2
High blood pressure	3.1	8.6	11.4	2.9	3.4	2.5
Chest pain or discomfort	3.1	4.4	8.5	-1.4	-1.7	-2.9
Medication: Aspirin	3.1	4.0	7.8	1.2	1.7	2.8
Number of live births	3.0	4.2	6.6	2.4	2.6	0.6
Ever had bowel cancer screening	3.0	3.5	5.3	1.9	2.3	1.4
Mean Putamen Volume	2.9	3.3	5.0	2.2	2.0	1.0
Schizophrenia vs Biploar Disorder	2.8	3.7	5.7	-2.4	-2.3	-0.3
Ever used hormone-replacement therapy (HRT)	2.8	3.6	4.2	2.0	1.6	2.1
Forced vital capacity (FVC)	2.8	10.8	18.0	3.6	4.2	1.1
Peak expiratory flow (PEF)	2.8	6.6	9.3	2.5	3.0	2.0
Birth weight	2.8	6.0	8.5	2.4	2.9	1.9
Hypertension (Self-reported)	2.8	7.7	10.7	2.9	3.3	2.0
Medication: Lisinopril	2.7	3.5	5.4	2.3	2.3	-0.2
Gout (self-reported)	2.6	3.6	3.8	1.9	2.0	1.8
Vascular/heart problems diagnosed by doctor	2.6	7.2	9.5	-2.3	-3.1	-2.6
Reaction Time	2.5	4.7	7.2	2.7	2.6	0.2
Current tobacco smoking	2.5	4.1	7.3	-2.1	-2.7	-0.8
Illnesses of siblings	2.5	3.6	6.5	1.7	1.2	2.5
Mean time to correctly identify matches	2.5	4.8	8.7	3.0	2.3	0.7
Number of treatments/medications taken	2.4	4.3	7.1	2.1	2.7	1.2
Fed-up feelings	2.4	4.4	5.6	2.4	2.4	1.5
Ever had prostate specific antigen (PSA) test	2.4	2.8	4.4	2.1	2.0	0.1
Fluid intelligence score	2.3	4.7	7.0	-2.7	-2.2	-1.6
Worrier / anxious feelings	2.3	4.3	6.3	1.4	2.5	2.1
Medication for cholesterol	2.3	3.4	5.2	-2.3	-1.8	-1.4
Forced expiratory volume in 1-second (FEV1)	2.2	7.3	11.7	3.0	3.4	1.1
Heart disease (siblings)	2.2	2.7	3.7	-1.9	-1.7	-1.2
Chronic bronchitis/emphysema (father)	2.0	2.3	2.8	1.6	1.7	1.3
Forced vital capacity (FVC), Best measure	2.0	7.2	11.9	2.8	3.5	1.3
Osteoarthritis (self-reported)	2.0	2.6	5.5	-1.2	-2.3	-0.9
Pack years of smoking	2.0	3.0	4.3	-1.4	-2.1	-1.6
Lung FVC	1.9	9.8	15.8	3.1	4.0	2.0
Ever had hysterectomy (womb removed)	1.9	2.2	3.9	1.5	2.0	0.5
Smoking status: Current	1.9	3.0	5.2	-1.7	-2.3	-1.0
Guilty feelings	1.9	2.9	3.5	1.5	1.9	1.7
High cholesterol (Self-reported)	1.9	3.3	5.1	1.5	1.6	2.2
Verbal and Numeric Reasoning (VNR)	1.8	4.3	6.1	-2.5	-2.4	-1.1
Bipolar Disorder (2011)	1.8	1.8	2.7	1.6	1.6	0.3
Had other major operations	1.8	2.2	2.6	1.6	1.4	1.4
Medication: Lansoprazole	1.8	2.1	3.4	1.8	1.5	0.8
Medication: Seretide 50 evohaler	1.8	2.1	3.5	1.6	1.9	0.5
Leg pain on walking	1.8	2.2	3.6	-1.8	-1.9	-0.0
Worry (Nagel 2018)	1.7	3.6	5.2	1.4	1.9	2.3
Rheumatoid Arthritis	1.7	2.3	4.4	-0.8	-1.4	-2.1
Lung FEV1/FVC ratio	1.7	8.4	12.3	-3.3	-3.5	-1.4
Hearing difficulty/problems: Yes	1.7	2.6	4.7	1.5	2.2	1.0
Pack years adult smoking proportion	1.7	2.6	4.0	-1.4	-2.0	-1.4
Townsend deprivation index at recruitment	1.7	2.4	4.0	-1.4	-1.1	-2.0
Multivitamins +/- minerals	1.7	2.2	3.3	1.5	1.8	1.0
Forced expiratory volume in 1-second (FEV1), predicted	1.7	3.5	5.2	2.3	1.8	1.5
Mood swings	1.7	3.0	4.6	1.9	2.1	0.9
Medication: Bendroflumethiazide	1.7	2.5	4.1	2.0	1.7	0.7
Medication: Atorvastatin	1.7	2.2	3.7	1.9	1.5	0.7
Basal cell carcinoma (self-reported)	1.7	2.0	3.3	-1.1	-1.8	-1.1
Coronary Artery Disease (CAD)	1.6	1.9	3.8	-1.9	-1.1	-0.8
Qualifications: None of the above	1.6	3.4	5.4	2.3	2.2	0.4
Loud music exposure frequency	1.6	1.7	2.6	1.6	1.6	-0.1
Knee pain experienced in last month	1.6	2.4	2.6	1.6	1.6	1.5
Average weekly beer plus cider intake	1.6	2.3	2.9	-1.1	-1.7	-1.6
Lung cancer (father)	1.5	1.8	2.8	1.3	1.7	1.0
Length of working week for main job	1.5	1.7	4.7	-0.4	-0.4	-2.2
Medication for pain relief, constipation, heartburn	1.5	2.6	5.6	-1.4	-2.4	-0.6
Smoking status: Previous	1.5	2.2	3.9	1.4	2.0	0.8
Breast cancer (self-reported)	1.5	1.8	2.2	1.5	1.4	1.1
Cholesterol lowering medication	1.5	2.2	2.9	1.6	1.1	1.7
Bipolar Disorder (2018)	1.4	2.2	4.3	2.1	1.5	0.3
Blood clot in the leg (DVT)	1.4	1.7	2.4	1.6	1.6	0.6
Heart disease (mother)	1.4	1.7	3.2	0.8	1.8	1.0
Illness, injury, bereavement, stress in last 2 years	1.4	1.8	3.4	-1.8	-1.3	-0.6
Back pain experienced in last month	1.4	2.1	6.2	-0.0	-0.3	-2.5
Hand grip strength (left)	1.3	3.3	5.5	1.6	2.4	1.4
Alcohol intake versus 10 years previously	1.3	2.0	2.8	-1.6	-1.7	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.2	6.7	2.2	2.6	1.1
Breastfed as a baby	1.3	1.7	3.0	-1.7	-1.1	0.9
Medication: Paracetamol	1.3	2.2	3.1	1.8	1.8	-0.7
Medication: Blood pressure	1.3	2.3	4.9	0.9	2.2	1.1
Number of operations (self-reported)	1.3	2.0	2.3	1.3	1.4	1.5
Diastolic blood pressure, automated reading	1.3	4.0	4.6	-2.0	-2.1	-1.8
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	2.4	1.5	1.5	0.7
Sensitivity / hurt feelings	1.2	2.0	3.4	0.9	1.9	1.4
Vitamin and mineral supplements	1.2	1.6	1.7	-1.2	-1.3	-1.2
Diabetes (mother)	1.2	1.5	3.3	0.7	0.9	1.8
Hayfever, allergic rhinitis or eczema	1.2	2.7	6.0	1.5	2.4	-0.2
Stomach or abdominal pain in last month	1.2	1.5	2.4	1.5	1.4	0.1
Number of incorrect matches in round	1.2	2.0	3.4	1.8	1.5	-0.5
Neuroticism score	1.2	2.5	3.1	1.7	1.7	1.3
Mouth/teeth dental problems: Loose teeth	1.2	1.5	2.4	-0.9	-1.1	-1.6
Emphysema/chronic bronchitis	1.2	1.4	1.8	1.4	1.4	0.7
Number of self-reported non-cancer illnesses	1.2	2.1	2.6	1.6	1.5	1.2
Intelligence (Savage-Jansen 2018)	1.1	3.4	6.1	-2.0	-2.5	-0.4
Height	1.1	20.4	30.8	5.5	5.1	2.2
Allergy or Eczema	1.1	2.9	5.8	1.1	2.4	1.3
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	3.2	-0.5	-0.4	-1.8
Medication: Metformin	1.1	1.6	2.4	1.2	1.6	0.9
Tinnitus: Yes, but not now, but have in the past	1.1	1.1	1.4	1.1	1.2	1.0
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	1.9	0.5	1.4	1.3
Allergy	1.1	2.5	4.9	-1.5	-2.2	0.3
Hair/balding pattern: Pattern 3	1.1	1.6	2.7	1.6	1.1	0.9
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	4.0	-0.8	-2.0	-1.0
Shortness of breath walking on level ground	1.1	1.3	2.0	1.1	0.8	1.4
Type 2 Diabetes (T2D) (2012)	1.0	1.2	1.7	-1.3	-1.2	-0.7
High blood pressure (mother)	1.0	1.4	2.5	1.3	1.6	0.0
Arm fat percentage (right)	1.0	3.8	5.5	-2.3	-1.8	-1.6
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	2.1	1.4	1.2	0.5
Number of children fathered	1.0	1.1	2.0	1.0	1.4	0.7
Average weekly red wine intake	1.0	1.5	3.0	0.7	1.0	1.7
Major Depression (MDD)	0.9	1.1	2.2	0.7	0.7	-1.5
Ovarian Cancer	0.9	1.1	2.8	0.2	0.7	1.7
Age when periods started (menarche)	0.9	2.3	3.3	1.8	1.6	1.0
Medication: Amlodipine	0.9	1.2	1.6	0.9	1.3	1.1
Chronic bronchitis/emphysema (mother)	0.9	1.1	2.2	1.5	1.0	0.1
Arm fat percentage (left)	0.9	3.4	4.8	-2.2	-1.8	-1.5
Eye problems/disorders: Cataract	0.9	1.1	2.1	-0.6	-0.9	1.4
Fasting Glucose	0.8	0.9	1.0	-1.0	-0.9	-0.9
Systolic blood pressure, automated reading	0.8	2.4	4.4	-1.3	-2.1	-1.1
Angina	0.8	1.1	1.7	1.3	1.2	0.1
Hand grip strength (right)	0.8	2.2	4.0	1.2	2.0	1.0
Had menopause	0.8	1.0	1.9	0.9	0.5	1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	4.2	0.8	0.9	2.1
Time employed in main current job	0.8	0.9	2.8	0.0	-0.2	1.7
Happiness	0.8	1.0	1.5	-1.1	-1.2	-0.5
Medication: Cholesterol lowering	0.8	1.2	2.0	0.9	1.4	0.9
High blood pressure (siblings)	0.8	1.2	3.4	-0.1	0.3	-1.8
Long-standing illness, disability or infirmity	0.8	1.2	1.8	1.3	1.4	0.2
Hearing aid user	0.8	0.9	1.4	-1.0	-0.5	-1.2
Chronotype (morning person)	0.7	1.5	2.5	-1.2	-1.6	-0.8
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	1.1	1.1	0.9	0.8
Standing height	0.7	6.8	9.7	2.9	3.1	1.6
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.3	-0.3	-0.6	-1.5
Arm fat-free mass (right)	0.7	3.8	6.4	1.1	2.5	2.0
Qualifications: College or University degree	0.7	2.2	4.1	-2.0	-1.6	0.3
Eye problems/disorders: None of the above	0.7	0.8	2.3	0.3	1.5	0.2
Angina (self-reported)	0.7	0.9	1.4	1.2	1.1	0.2
Arm predicted mass (right)	0.7	3.6	5.8	1.2	2.4	1.9
Age at last live birth	0.7	1.0	1.8	0.7	0.9	-1.3
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.5	1.2	0.7	0.6
Diabetes diagnosed by doctor	0.7	1.1	1.5	1.2	1.2	0.7
Financial situation satisfaction	0.7	0.9	1.0	0.8	1.0	1.0
Medication: Blood pressure	0.7	1.3	3.3	1.8	0.8	0.1
Age started oral contraceptive pill	0.7	0.9	1.8	-0.6	-1.3	-0.7
Unable to work because of sickness or disability	0.7	1.0	2.0	-1.4	-0.9	-0.2
Prostate Cancer	0.6	0.8	1.8	-1.3	-0.8	-0.1
BMI	0.6	3.3	6.3	-2.5	-1.4	-1.3
Type 2 Diabetes (T2D) (2018)	0.6	1.2	1.6	1.3	0.9	1.0
Severe depression (siblings)	0.6	0.6	1.3	-0.7	-0.3	-1.2
Trunk fat-free mass	0.6	3.5	6.0	1.2	2.5	1.8
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	1.5	-0.7	-0.9	-1.2
Trunk predicted mass	0.6	3.3	5.5	1.2	2.4	1.7
Exposure to tobacco smoke at home	0.6	0.7	1.6	1.3	0.1	-0.6
Medication: Omeprazole	0.6	0.7	1.7	-1.3	-0.0	-0.6
Miserableness	0.6	1.1	2.0	1.4	1.1	-0.0
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.1	1.1	1.0	-0.6
Arm fat-free mass (left)	0.6	3.2	5.6	1.0	2.4	1.7
Supplements: Calcium	0.6	0.7	1.6	0.2	0.6	1.3
Depression (Nagel 2018)	0.5	0.8	1.4	0.8	1.2	0.4
Smoking Status	0.5	1.2	1.6	-1.1	-1.3	-0.8
Cardiovascular Disease	0.5	1.7	1.8	1.3	1.4	1.3
Medication: Co-codamol	0.5	0.5	1.0	1.0	0.7	-0.3
Trunk fat percentage	0.5	1.8	2.4	-1.6	-1.3	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	0.8	0.9	0.9	-0.7
Serious illness, injury or assault to yourself	0.5	0.6	1.3	1.1	0.7	-0.0
Sitting height	0.5	3.6	5.7	2.2	2.4	0.3
Alcohol usually taken with meals	0.5	0.8	2.2	-0.2	0.6	1.5
Hair/balding pattern: Pattern 2	0.5	0.7	1.5	0.6	1.2	-0.3
Financial difficulties in last 2 years	0.5	0.7	1.2	0.9	1.1	-0.5
Pain all over the body in last month	0.5	0.6	1.2	0.0	-0.7	-1.1
Diabetes (self-reported)	0.5	0.7	0.9	0.9	0.9	0.6
Headache pain in last month	0.5	0.9	2.5	-0.2	0.0	-1.6
Glaucoma (self-reported)	0.5	0.6	1.0	0.9	0.0	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	0.9	0.9	0.8	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.0	-1.0	0.3	-0.8
Pain experienced in last month	0.5	0.8	0.9	-1.0	-1.0	0.7
Arm predicted mass (left)	0.5	2.7	5.2	0.9	2.3	1.5
Schizophrenia (2018)	0.4	0.8	1.6	-1.3	-0.8	-0.5
Alzheimer’s Disease (in mother)	0.4	0.5	1.4	-0.2	-1.2	0.0
Ulcerative Colitis (UC)	0.4	0.7	0.9	0.9	1.0	-0.7
Lupus	0.4	0.7	1.1	0.9	1.1	-0.1
Primary Biliary Cirrhosis	0.4	0.6	1.0	0.7	1.0	-0.5
Triglycerides	0.4	0.7	1.2	0.4	0.9	1.1
Blood Platelet Count	0.4	5.2	6.7	-1.5	-2.6	-2.6
Heel T-Score	0.4	3.1	4.1	-2.0	-1.3	-1.9
Relative age of first facial hair	0.4	0.8	1.5	1.2	0.9	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.1	0.9	1.0	0.4
Heart attack	0.4	0.6	1.3	-1.1	-0.4	0.5
Medication: Ramipril	0.4	0.5	1.1	-0.5	-0.3	1.1
Impedance of arm (right)	0.4	2.1	3.5	-0.3	-1.9	-1.6
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.2	-1.0	-1.1	0.8
Pulse wave Arterial Stiffness index	0.4	0.5	1.2	0.5	-0.0	1.1
Impedance of arm (left)	0.4	1.8	3.2	-0.1	-1.8	-1.5
Birth weight of first child	0.4	0.7	1.2	-0.8	-0.4	-1.1
Body fat percentage	0.4	1.5	1.9	-1.4	-1.1	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.0	-0.2	1.0	-0.5
Age at first live birth	0.4	0.6	1.3	-0.5	-0.5	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.0	-0.7	0.0	-1.0
Whole body fat-free mass	0.4	2.3	4.2	0.7	2.0	1.5
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.2	-0.5	-1.1	-0.1
Friendships satisfaction	0.4	0.5	1.0	-0.5	-1.0	-0.5
Whole body water mass	0.4	2.5	4.4	0.8	2.1	1.6
Eye problems/disorders: Glaucoma	0.4	0.4	1.0	1.0	-0.3	-0.4
Medication: Paracetamol	0.4	0.7	0.9	0.6	0.9	-0.9
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.0	-1.0	-0.1	0.7
Ulcerative Colitis	0.3	0.5	1.4	0.2	0.3	-1.2
Respiratory disease	0.3	0.6	0.8	-0.9	-0.9	0.4
Impedance of leg (right)	0.3	1.7	4.5	2.1	0.8	-0.1
Body mass index (BMI)	0.3	1.2	3.0	-1.7	-0.8	-0.4
Impedance of leg (left)	0.3	1.4	3.8	2.0	0.5	-0.4
Past tobacco smoking	0.3	0.5	1.2	-0.6	-1.1	0.1
Nervous feelings	0.3	0.6	0.9	0.9	0.9	-0.4
Mouth/teeth dental problems	0.3	0.4	1.0	-0.5	-0.1	1.0
Depression (self-reported)	0.3	0.3	0.7	0.8	0.3	-0.4
Exposure to tobacco smoke outside home	0.3	0.3	0.7	0.6	0.1	-0.9
Comparative body size at age 10	0.3	0.9	1.9	0.9	1.4	0.1
Number of full brothers	0.3	0.4	0.9	-0.0	-0.5	-1.0
Wheeze or whistling in the chest in last year	0.3	0.5	0.8	0.9	0.7	-0.5
Pulse wave peak to peak time	0.3	0.3	0.9	-0.1	0.4	-0.9
Migraine (self-reported)	0.3	0.4	1.0	0.1	-0.5	-1.0
Medication: Ibuprofen	0.3	0.4	0.5	0.6	0.7	0.5
Alcohol intake frequency.	0.3	0.6	0.9	1.0	0.5	-0.8
Had major operations	0.3	0.3	0.5	-0.4	-0.7	-0.7
Supplements: Vitamin C	0.3	0.3	0.6	-0.1	-0.7	0.8
Commuting to job workplace: Walk	0.3	0.3	0.7	-0.4	0.4	0.9
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.8	0.5	0.9	-0.7
Ever taken oral contraceptive pill	0.3	0.3	0.5	0.3	0.6	0.7
Basal metabolic rate	0.3	1.7	3.2	0.5	1.8	1.2
Irritability	0.3	0.5	0.8	-0.9	-0.2	-0.8
Ever depressed for a whole week	0.3	0.4	0.7	0.8	0.7	0.1
Alzheimer’s Disease (including proxy)	0.2	0.3	0.8	-0.1	-0.9	-0.1
Age at First Birth	0.2	0.3	0.4	-0.3	-0.6	-0.6
Neuroticism (2016)	0.2	0.3	0.8	-0.0	0.3	-0.9
Schizophrenia (2014)	0.2	0.5	1.0	-1.0	-0.7	-0.1
Blood White Count	0.2	1.7	3.0	-1.4	-1.7	-0.3
Diabetes (father)	0.2	0.3	0.6	0.8	-0.0	-0.5
Leg fat-free mass (left)	0.2	0.8	1.5	-0.1	1.2	1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.4	0.3	0.3	1.2
Qualifications: CSEs or equivalent	0.2	0.3	0.7	0.8	-0.3	0.4
Supplements: Glucosamine	0.2	0.3	0.7	-0.1	0.3	0.9
Leg predicted mass (left)	0.2	0.8	1.5	-0.1	1.2	1.0
Waist circumference	0.2	0.7	1.7	-1.3	-0.6	-0.4
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.8	-0.4	-0.2	-0.9
Hip circumference	0.2	0.7	1.6	-1.3	-0.5	-0.5
Father’s age at death	0.2	0.3	0.9	0.1	-0.3	-0.9
Arm fat mass (right)	0.2	0.9	2.0	-1.4	-0.5	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.4	0.6	0.4	0.6
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	0.9	-0.1	-0.4	1.0
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.8	0.1	0.0	-0.9
Leg fat percentage (right)	0.2	0.7	1.1	-1.1	-0.6	-0.8
Worry too long after embarrassment	0.2	0.4	0.6	0.4	0.8	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.6	0.7	-0.1	-0.3
Overall health rating	0.2	0.3	0.6	0.3	0.6	-0.8
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.4	-0.3	-0.3	-0.6
Illnesses of father: Heart disease	0.2	0.2	0.5	-0.7	-0.1	0.5
Arm fat mass (left)	0.2	0.6	1.5	-1.2	-0.4	-0.5
Commuting to job workplace: Public transport	0.2	0.3	0.6	-0.8	-0.3	-0.4
Alcohol drinker status: Never	0.2	0.2	0.3	0.0	-0.6	-0.6
Ever smoked	0.2	0.4	0.9	-0.9	-0.4	-0.3
Leg fat percentage (left)	0.2	0.7	1.1	-1.0	-0.6	-0.8
Commuting to job workplace: Cycle	0.2	0.2	0.4	0.6	0.2	0.5
Myopia	0.2	0.2	0.3	-0.4	-0.5	-0.5
Impedance of whole body	0.2	1.1	1.8	0.7	-1.0	-1.4
Alzheimer’s Disease (in father)	0.1	0.1	0.1	0.4	-0.1	0.4
Irritable Bowel Disease (IBD)	0.1	0.2	0.4	0.4	0.6	-0.2
Breast Cancer	0.1	0.3	0.8	-0.2	-0.3	0.9
HDL Cholesterol	0.1	0.1	0.1	-0.2	-0.3	-0.3
LDL Cholesterol	0.1	0.1	0.3	-0.2	0.1	0.6
Blood Red Count	0.1	1.2	2.7	-0.5	-0.9	-1.6
Waist Hip Ratio (WHR)	0.1	0.3	0.9	0.1	-0.1	0.9
Systolic Blood Pressure	0.1	0.7	1.5	-0.5	-1.2	-0.5
Hypothyroidism (self reported)	0.1	0.1	0.3	0.6	0.2	-0.2
Average weekly spirits intake	0.1	0.2	0.3	-0.1	0.5	-0.5
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.4	0.3	0.6	0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.4	-0.2	0.1	0.6
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.3	0.5	0.2	-0.1
Medication: Atenolol	0.1	0.1	0.3	-0.5	-0.0	0.2
Medication: Levothyroxine sodium	0.1	0.2	0.3	-0.5	-0.6	0.3
Trunk fat mass	0.1	0.6	1.2	-1.1	-0.5	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.2	0.5	0.3	-0.3
Prospective memory result	0.1	0.1	0.1	-0.3	-0.3	-0.2
Tense / ‘highly strung’	0.1	0.1	0.2	-0.3	-0.4	0.1
Hair/balding pattern: Pattern 4	0.1	0.1	0.3	-0.5	-0.3	-0.2
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.4	-0.1	0.1	-0.6
Whole body fat mass	0.1	0.5	1.0	-1.0	-0.3	-0.5
Comparative height size at age 10	0.1	0.5	0.7	0.8	0.8	-0.4
Number of full sisters	0.1	0.1	0.2	0.2	-0.1	-0.5
Illnesses of siblings: Diabetes	0.1	0.1	0.3	-0.2	-0.5	-0.3
Leg fat-free mass (right)	0.1	0.8	1.3	-0.2	1.1	1.0
Qualifications: nursing, teaching	0.1	0.1	0.2	-0.5	0.2	0.2
Mineral and other dietary supplements	0.1	0.1	0.2	0.1	-0.2	-0.5
Leg predicted mass (right)	0.1	0.8	1.3	-0.2	1.1	1.0
Average weekly champagne plus white wine intake	0.1	0.2	0.3	-0.5	0.1	-0.6
Wears glasses or contact lenses	0.1	0.1	0.2	-0.4	-0.2	0.2
Mother’s age at death	0.1	0.1	0.2	0.5	-0.3	0.3
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	0.2	0.3	-0.4
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.5	-0.7	-0.0	0.1
Risk taking	0.1	0.1	0.2	-0.5	-0.4	0.1
Bipolar Disorder or Schizophrenia	0.0	0.1	0.1	0.3	0.4	-0.2
Crohns Disease (2017)	0.0	0.1	0.1	0.1	0.3	0.3
Body Mass Index (BMI) (2010)	0.0	0.1	0.1	0.1	0.4	0.1
Crohns Disease (2012)	0.0	0.0	0.1	-0.3	-0.2	-0.0
Blood Eosinophil Count	0.0	0.3	0.5	-0.7	-0.6	0.1
Hair Pigment	0.0	0.2	0.5	-0.0	0.2	-0.7
Tanning	0.0	0.5	0.9	0.4	0.6	0.9
Relative age voice broke	0.0	0.0	0.1	0.2	-0.0	0.1
Taking other prescription medications	0.0	0.1	0.1	0.3	0.1	-0.4
Medication: Simvastatin	0.0	0.0	0.0	0.2	0.0	0.2
Weight	0.0	0.2	0.4	-0.3	0.6	0.3
Falls in the last year	0.0	0.0	0.0	-0.2	-0.1	0.2
Noisy workplace	0.0	0.0	0.1	0.2	0.0	-0.3
Mouth/teeth dental problems: Dentures	0.0	0.1	0.2	-0.0	-0.1	0.4
Asthma	0.0	0.1	0.2	-0.2	-0.3	-0.4
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.1	0.2	0.0	0.3
Health satisfaction	0.0	0.1	0.1	0.1	-0.2	0.3
Leg fat mass (right)	0.0	0.1	0.4	-0.6	0.3	-0.0
Family relationship satisfaction	0.0	0.1	0.1	-0.4	-0.0	0.2
Loneliness, isolation	0.0	0.0	0.1	0.2	-0.1	0.2
Asthma (self-reported)	0.0	0.0	0.1	-0.0	-0.1	-0.3
Illnesses of father: None of the above (group 1)	0.0	0.0	0.1	-0.2	-0.0	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.2	0.1	0.1	0.5
Alcohol drinker status: Previous	0.0	0.1	0.1	0.0	-0.1	-0.4
Leg fat mass (left)	0.0	0.2	0.5	-0.7	0.2	-0.2

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LOC339524

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