TWAS hub - LOC375190

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.1020	0.0440	6.2e-07	0.092	0.069	0.071	NA	0.082	3.7e-08	1.9e-06	1.2e-06	NA	1.9e-07
2	TCGA	Breast Invasive Carcinoma	0.2108	0.0556	0.0e+00	0.215	0.221	0.216	NA	0.218	6.0e-43	2.3e-44	3.5e-43	NA	1.2e-43
3	TCGA	Cervical Squamous Cell Carcinoma	0.1740	0.0690	1.9e-06	0.128	0.073	0.048	NA	0.118	7.4e-07	1.8e-04	2.2e-03	NA	2.1e-06
4	TCGA	Colon Adenocarcinoma	0.1120	0.0540	2.4e-04	0.060	0.039	0.019	NA	0.037	2.2e-04	2.6e-03	2.8e-02	NA	3.3e-03
5	TCGA	Esophageal Carcinoma	0.1160	0.0600	1.8e-03	0.134	0.089	0.094	NA	0.111	4.8e-05	9.0e-04	6.5e-04	NA	2.2e-04
6	TCGA	Glioblastoma Multiforme	0.1490	0.0690	3.5e-04	0.075	0.094	0.062	NA	0.082	2.8e-03	8.8e-04	6.1e-03	NA	1.8e-03
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.0538	0.0223	1.7e-07	0.078	0.067	0.076	NA	0.078	4.0e-09	5.7e-08	6.1e-09	NA	4.4e-09
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.2455	0.0729	0.0e+00	0.246	0.266	0.254	NA	0.264	2.0e-27	6.4e-30	2.2e-28	NA	1.3e-29
9	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2040	0.0680	2.3e-11	0.213	0.197	0.208	NA	0.217	2.3e-12	1.7e-11	4.3e-12	NA	1.4e-12
10	TCGA	Brain Lower Grade Glioma	0.3056	0.0753	0.0e+00	0.280	0.367	0.365	NA	0.364	7.6e-32	1.3e-43	2.1e-43	NA	3.0e-43
11	TCGA	Lung Adenocarcinoma	0.2012	0.0721	0.0e+00	0.132	0.161	0.172	NA	0.159	3.2e-15	2.3e-18	1.2e-19	NA	3.7e-18
12	TCGA	Lung Squamous Cell Carcinoma	0.1342	0.0478	4.9e-11	0.050	0.106	0.086	NA	0.080	2.3e-06	5.3e-12	5.4e-10	NA	2.2e-09
13	TCGA	Ovarian Serous Cystadenocarcinoma	0.1120	0.0510	7.1e-07	0.049	0.079	0.080	NA	0.076	2.9e-04	5.2e-06	4.3e-06	NA	8.0e-06
14	TCGA	Pancreatic Adenocarcinoma	0.2040	0.0720	2.5e-06	0.196	0.162	0.162	NA	0.175	1.2e-08	2.6e-07	2.6e-07	NA	7.8e-08
15	TCGA	Pheochromocytoma and Paraganglioma	0.2250	0.0930	2.5e-05	0.188	0.145	0.132	NA	0.177	5.8e-08	2.1e-06	6.3e-06	NA	1.5e-07
16	TCGA	Prostate Adenocarcinoma	0.2398	0.0606	0.0e+00	0.338	0.364	0.372	NA	0.372	2.1e-36	1.1e-39	8.0e-41	NA	7.6e-41
17	TCGA	Rectum Adenocarcinoma	0.3070	0.1300	8.7e-04	0.177	0.070	0.113	NA	0.132	6.0e-05	1.0e-02	1.3e-03	NA	5.5e-04
18	TCGA	Skin Cutaneous Melanoma	0.2230	0.0950	4.5e-04	0.101	0.126	0.135	NA	0.145	1.2e-03	3.1e-04	1.9e-04	NA	1.1e-04
19	TCGA	Stomach Adenocarcinoma	0.0780	0.0320	6.0e-06	0.070	0.083	0.072	NA	0.064	8.6e-06	1.2e-06	6.2e-06	NA	2.0e-05
20	TCGA	Testicular Germ Cell Tumors	0.1200	0.0680	2.3e-03	0.035	0.064	0.010	NA	0.030	2.1e-02	2.7e-03	1.4e-01	NA	3.1e-02
21	TCGA	Thyroid Carcinoma	0.4600	0.0770	0.0e+00	0.500	0.524	0.541	NA	0.531	1.2e-55	1.9e-59	2.8e-62	NA	1.7e-60
22	TCGA	Uterine Corpus Endometrial Carcinoma	0.1840	0.0830	6.6e-04	0.174	0.091	0.122	NA	0.143	1.4e-05	1.7e-03	2.9e-04	NA	8.7e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Medication: Seretide 50 evohaler	8.0	9.2	14.0	2.5	2.8	3.0	3.6	2.2	3.4	2.5	3.2	3.3	3.3	3.7	2.8	3.6	2.4	2.4	3.2	2.4	3.0	2.8	3.7	3.4	2.4
Serious illness, injury or assault to yourself	5.9	7.2	9.7	2.6	2.5	2.9	2.9	1.9	2.8	2.4	3.0	2.7	2.9	2.5	2.6	3.0	2.5	2.5	2.8	2.5	2.4	3.0	3.1	2.7	2.5
Qualifications: O levels/GCSEs or equivalent	4.9	7.8	11.4	2.5	2.6	2.8	2.8	2.2	3.2	2.5	2.7	3.1	3.1	3.0	3.0	3.4	2.4	2.4	3.1	2.4	2.6	2.7	3.3	2.9	2.4
Wears glasses or contact lenses	4.5	5.2	6.5	-2.3	-2.5	-2.2	-1.9	-2.3	-2.3	-2.4	-2.0	-2.3	-2.5	-1.9	-2.5	-2.1	-2.3	-2.3	-2.4	-2.3	-1.9	-2.3	-2.3	-2.2	-2.3
Reaction Time	4.4	8.4	23.6	1.8	2.1	2.6	3.3	1.3	3.8	1.7	3.0	2.8	3.2	3.1	3.1	4.5	1.6	1.6	3.1	1.6	3.0	3.5	4.9	3.0	1.6
Emphysema/chronic bronchitis	4.2	4.8	8.3	2.0	2.3	2.2	2.8	1.8	2.2	1.9	2.4	2.2	2.2	2.9	1.5	2.4	2.0	1.9	2.2	1.9	2.3	1.9	2.2	2.2	1.9
Severe depression (siblings)	3.8	4.3	6.9	-2.5	-2.6	-2.0	-1.9	-2.3	-1.2	-2.5	-1.8	-2.4	-1.9	-2.2	-1.4	-1.0	-2.6	-2.6	-2.1	-2.6	-0.9	-0.7	-1.0	-2.5	-2.6
Pulse wave reflection index	3.7	4.6	8.3	-2.4	-2.9	-2.2	-2.7	-2.0	-1.3	-2.3	-2.3	-2.5	-2.1	-1.9	-1.7	-1.8	-2.4	-2.4	-2.2	-2.4	-1.5	-0.6	-1.1	-2.3	-2.4
Other serious medical condition/disability diagnosed by doctor	3.6	4.7	5.6	2.4	2.3	2.3	2.3	2.2	1.8	2.3	2.3	2.1	2.1	2.3	2.1	1.9	2.4	2.4	2.0	2.4	2.3	1.7	1.5	2.0	2.4
Medication: Lansoprazole	3.4	3.9	6.8	-1.9	-1.9	-2.1	-2.4	-2.0	-2.1	-2.0	-1.9	-2.3	-2.2	-1.7	-1.0	-1.6	-1.8	-1.9	-2.2	-1.9	-2.6	-1.9	-1.9	-1.8	-1.9
Number of full sisters	3.4	4.2	5.8	-2.0	-2.0	-2.1	-2.4	-2.2	-2.2	-2.1	-1.9	-2.2	-2.3	-1.8	-1.6	-1.7	-1.9	-1.9	-2.2	-1.9	-2.4	-2.1	-2.0	-1.8	-1.9
Comparative body size at age 10	3.0	8.3	13.2	-2.6	-2.1	-2.9	-3.1	-3.0	-3.6	-2.8	-2.6	-3.1	-3.2	-3.6	-2.2	-2.4	-2.5	-2.5	-3.2	-2.5	-2.7	-3.2	-3.6	-2.6	-2.5
LDL Cholesterol	2.8	4.4	6.7	-2.0	-2.4	-2.1	-2.3	-2.0	-1.9	-2.0	-2.4	-2.2	-2.6	-1.9	-2.5	-1.9	-1.9	-1.9	-2.2	-1.9	-2.0	-1.9	-1.9	-2.1	-1.9
Angina	2.8	3.6	5.0	-1.9	-1.7	-1.9	-2.2	-1.7	-2.1	-1.9	-1.7	-2.1	-2.0	-1.9	-1.5	-2.2	-1.8	-1.8	-2.1	-1.8	-1.9	-1.7	-2.2	-1.7	-1.8
Worry too long after embarrassment	2.8	4.6	7.3	-2.0	-1.9	-2.1	-2.0	-2.4	-2.7	-2.2	-1.9	-2.3	-2.2	-1.7	-1.7	-1.9	-2.0	-2.0	-2.3	-2.0	-2.7	-2.5	-2.3	-2.0	-2.0
Suffer from ‘nerves’	2.8	4.4	7.0	-2.0	-2.2	-2.1	-2.2	-2.3	-2.2	-2.2	-1.8	-2.6	-2.5	-2.0	-2.0	-1.6	-1.9	-2.0	-2.4	-2.0	-1.9	-1.4	-2.0	-2.3	-2.0
Schizophrenia vs Biploar Disorder	2.7	3.5	5.2	-1.8	-2.0	-2.0	-2.0	-1.3	-2.0	-1.6	-2.1	-1.8	-1.8	-1.9	-1.8	-2.3	-1.7	-1.7	-1.9	-1.7	-1.5	-2.0	-2.2	-2.1	-1.7
Type 2 Diabetes (T2D) (2012)	2.7	3.1	4.1	1.9	1.5	2.0	1.7	1.7	2.0	1.8	1.8	1.9	1.7	2.0	1.3	1.5	1.8	1.8	1.8	1.8	1.5	1.7	1.6	2.0	1.8
Angina (self-reported)	2.7	3.6	4.9	-1.9	-1.8	-1.9	-2.2	-1.6	-2.0	-1.9	-1.7	-2.1	-2.0	-1.9	-1.5	-2.2	-1.8	-1.8	-2.1	-1.8	-1.9	-1.6	-2.2	-1.7	-1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.7	3.3	5.8	-2.2	-2.4	-1.9	-1.8	-1.9	-1.1	-2.1	-2.1	-1.7	-1.6	-1.0	-1.8	-1.1	-2.3	-2.3	-1.6	-2.3	-1.0	-1.1	-0.8	-2.0	-2.3
Medication: Paracetamol	2.7	4.2	6.0	2.4	2.2	2.1	1.6	2.3	1.9	2.3	2.2	1.5	1.6	2.1	2.4	1.8	2.4	2.4	1.8	2.4	1.2	2.1	1.5	1.8	2.4
Fractured/broken bones in last 5 years	2.7	3.5	7.8	-1.9	-2.2	-1.9	-2.8	-2.1	-1.5	-2.0	-1.7	-2.3	-1.9	-1.9	-0.4	-1.2	-1.8	-1.8	-2.0	-1.8	-2.5	-1.1	-1.2	-1.8	-1.8
Eye problems/disorders: Diabetes related eye disease	2.6	2.9	6.4	1.1	1.4	1.5	2.0	0.9	2.1	1.1	2.2	1.6	2.0	1.7	1.8	2.4	1.0	1.0	1.7	1.0	1.8	2.2	2.5	1.8	1.0
Illnesses of mother	2.5	3.1	7.1	-1.5	-2.2	-1.8	-1.6	-1.2	-1.7	-1.5	-1.7	-2.0	-2.0	-1.3	-2.7	-2.4	-1.5	-1.5	-1.9	-1.5	-1.7	-1.3	-1.7	-1.7	-1.5
Had major operations	2.5	2.9	5.7	1.3	1.4	1.6	2.2	1.3	2.1	1.4	1.7	1.9	1.9	2.2	1.2	1.9	1.2	1.2	1.8	1.2	2.1	1.8	2.4	1.7	1.2
Risk taking	2.5	3.7	8.4	1.6	1.8	1.7	1.7	1.1	2.3	1.6	1.9	1.9	2.2	1.6	2.7	2.7	1.6	1.6	2.1	1.6	1.0	2.1	2.9	2.0	1.6
Financial situation satisfaction	2.4	3.0	5.7	-1.6	-1.9	-1.9	-2.4	-1.4	-1.7	-1.5	-2.0	-2.0	-2.2	-1.0	-1.6	-1.5	-1.5	-1.5	-1.7	-1.5	-2.1	-1.5	-1.5	-1.8	-1.5
Alzheimer’s Disease (including proxy)	2.3	3.3	5.6	1.6	2.1	1.8	2.4	1.3	1.5	1.6	1.8	2.3	2.1	2.0	1.5	2.2	1.5	1.5	2.1	1.5	1.9	1.2	1.9	1.9	1.5
Lung FVC	2.2	11.3	17.7	3.3	3.2	3.4	2.6	2.8	3.6	3.3	3.2	4.0	3.7	2.4	4.2	3.7	3.2	3.2	3.9	3.2	2.4	2.9	3.7	4.2	3.2
Leg fat percentage (left)	2.2	8.0	15.8	-2.2	-3.0	-2.6	-3.0	-2.2	-2.9	-2.4	-2.7	-3.6	-4.0	-2.6	-3.8	-2.9	-2.0	-2.0	-3.3	-2.0	-2.3	-2.0	-3.6	-3.3	-2.0
Age when periods started (menarche)	2.1	5.1	8.4	2.8	2.1	2.6	1.9	2.9	1.9	2.8	2.2	2.3	2.0	1.7	1.1	0.6	2.9	2.9	2.2	2.9	1.8	1.9	1.0	2.3	2.9
Heart attack/myocardial infarction (self-reported)	2.1	2.8	4.1	1.6	2.0	1.7	1.9	1.6	1.7	1.6	1.8	1.7	1.8	1.1	1.4	1.4	1.6	1.6	1.7	1.6	2.0	1.9	1.5	1.6	1.6
Body fat percentage	2.0	7.9	14.9	-2.4	-3.1	-2.6	-2.9	-2.5	-2.7	-2.6	-2.6	-3.5	-3.9	-2.5	-3.7	-2.6	-2.3	-2.3	-3.2	-2.3	-2.4	-2.0	-3.3	-3.2	-2.3
Frequency of depressed mood in last 2 weeks	1.9	2.7	4.7	-1.4	-2.2	-1.4	-2.0	-1.7	-1.5	-1.6	-1.4	-2.1	-2.1	-1.3	-0.9	-1.2	-1.3	-1.4	-2.0	-1.4	-2.0	-1.2	-1.8	-1.9	-1.4
Sitting height	1.9	13.3	46.6	1.8	3.2	2.8	3.5	1.0	5.1	1.8	3.6	4.1	4.5	2.3	5.2	6.1	1.5	1.5	4.1	1.5	2.0	3.6	6.8	4.6	1.5
Heart attack	1.9	2.4	4.1	1.5	2.0	1.6	1.8	1.5	1.5	1.5	1.8	1.5	1.7	1.0	1.3	1.3	1.5	1.5	1.5	1.5	1.9	1.7	1.3	1.5	1.5
Leg fat percentage (right)	1.9	6.9	14.1	-1.9	-2.8	-2.3	-2.9	-2.0	-2.7	-2.1	-2.5	-3.4	-3.8	-2.7	-3.5	-2.9	-1.7	-1.7	-3.1	-1.7	-2.3	-1.8	-3.5	-3.1	-1.7
Arm fat percentage (left)	1.9	7.4	12.5	-2.5	-2.9	-2.5	-2.5	-2.6	-2.6	-2.7	-2.5	-3.2	-3.5	-2.1	-3.5	-2.4	-2.5	-2.5	-3.1	-2.5	-2.1	-2.1	-3.1	-3.0	-2.5
Medication: Paracetamol	1.8	2.9	4.4	2.0	2.1	1.7	1.5	1.7	1.4	1.8	2.1	1.1	1.2	1.9	1.8	1.6	2.0	2.0	1.3	2.0	0.8	1.7	1.1	1.7	2.0
Illnesses of father: Heart disease	1.8	2.5	4.1	1.8	2.0	1.7	1.7	1.4	1.3	1.6	2.0	1.6	1.6	1.4	1.7	1.5	1.8	1.8	1.5	1.8	0.9	1.0	1.2	1.7	1.8
Leg fat mass (left)	1.8	7.0	12.1	-2.5	-2.8	-2.6	-3.0	-2.8	-2.4	-2.7	-2.4	-3.2	-3.5	-2.7	-2.8	-1.9	-2.4	-2.4	-3.0	-2.4	-2.6	-1.9	-2.6	-2.8	-2.4
Alzheimer’s Disease (in mother)	1.7	2.0	5.0	1.2	1.8	1.3	1.5	0.7	1.1	1.1	1.6	1.7	1.5	1.2	1.8	2.2	1.1	1.1	1.5	1.1	1.0	0.8	1.6	1.8	1.1
Trunk fat percentage	1.7	7.0	13.2	-2.3	-2.9	-2.4	-2.7	-2.4	-2.4	-2.5	-2.4	-3.2	-3.6	-2.4	-3.5	-2.3	-2.2	-2.2	-3.0	-2.2	-2.4	-1.9	-3.0	-3.0	-2.2
Body mass index (BMI)	1.7	7.3	10.8	-2.7	-2.8	-2.7	-2.7	-2.8	-2.6	-2.8	-2.5	-3.2	-3.3	-2.5	-3.0	-2.1	-2.7	-2.7	-3.0	-2.7	-2.1	-2.1	-2.7	-3.0	-2.7
Arm fat percentage (right)	1.7	6.8	11.1	-2.5	-2.8	-2.4	-2.4	-2.5	-2.5	-2.6	-2.3	-3.1	-3.3	-2.1	-3.3	-2.3	-2.4	-2.5	-3.0	-2.5	-1.9	-2.0	-2.9	-2.9	-2.5
Forced vital capacity (FVC), Best measure	1.7	6.3	15.1	2.3	2.5	2.3	1.6	2.3	3.0	2.5	2.1	3.0	2.9	0.8	3.9	2.8	2.3	2.3	2.9	2.3	1.4	2.2	3.1	2.9	2.3
Eye problems/disorders: None of the above	1.7	1.9	6.0	-1.0	-1.2	-1.4	-1.1	-0.3	-1.7	-0.7	-1.8	-1.3	-1.5	-0.9	-2.4	-2.4	-0.9	-0.9	-1.3	-0.9	-1.3	-1.6	-1.8	-1.5	-0.9
BMI	1.6	9.1	11.4	-3.2	-3.0	-3.1	-2.7	-3.3	-3.1	-3.3	-2.9	-3.2	-3.4	-2.4	-3.3	-2.1	-3.1	-3.2	-3.2	-3.2	-2.3	-3.0	-2.8	-3.1	-3.2
Medication: Co-codamol	1.6	1.9	3.3	1.5	1.2	1.7	1.3	0.8	1.4	1.2	1.7	1.5	1.0	1.8	1.2	1.8	1.4	1.4	1.3	1.4	0.9	1.0	1.0	1.6	1.4
Hip circumference	1.6	7.0	10.2	-3.0	-2.7	-2.8	-2.6	-3.2	-2.0	-3.1	-2.3	-2.9	-2.7	-2.7	-2.0	-1.4	-3.0	-3.1	-2.7	-3.1	-2.6	-2.0	-1.6	-2.7	-3.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.0	12.4	2.0	2.3	2.0	1.5	2.0	2.6	2.2	1.8	2.7	2.6	0.7	3.5	2.5	2.0	2.0	2.7	2.0	1.3	1.8	2.8	2.5	2.0
Ever taken oral contraceptive pill	1.6	1.8	4.0	1.1	0.8	1.2	1.1	1.2	1.9	1.2	1.1	1.2	1.4	1.4	1.6	1.7	1.0	1.0	1.4	1.0	1.3	1.9	2.0	1.2	1.0
Depression (Nagel 2018)	1.5	2.2	3.9	-1.3	-2.0	-1.3	-1.7	-1.5	-1.4	-1.5	-1.4	-1.8	-1.8	-0.9	-1.0	-1.3	-1.3	-1.3	-1.8	-1.3	-1.4	-1.3	-1.8	-1.8	-1.3
Systolic blood pressure, automated reading	1.5	4.4	7.7	-2.0	-1.2	-1.9	-1.2	-2.6	-2.8	-2.3	-1.2	-2.3	-2.3	-1.0	-2.4	-1.7	-2.0	-2.0	-2.4	-2.0	-2.3	-2.6	-2.5	-1.8	-2.0
High blood pressure (mother)	1.5	2.0	3.8	1.4	1.9	1.4	1.4	1.2	1.3	1.3	1.5	1.4	1.5	1.5	1.6	1.6	1.3	1.3	1.5	1.3	1.1	1.2	1.4	1.4	1.3
Hearing difficulty/problems with background noise	1.5	2.3	4.2	-1.2	-1.5	-1.5	-2.1	-1.4	-1.9	-1.3	-1.5	-1.5	-1.8	-0.8	-1.2	-1.4	-1.2	-1.2	-1.6	-1.2	-2.1	-2.0	-1.9	-1.3	-1.2
Arm fat mass (right)	1.5	6.2	9.0	-2.6	-2.6	-2.5	-2.6	-2.8	-2.1	-2.7	-2.2	-2.9	-3.0	-2.5	-2.4	-1.5	-2.6	-2.6	-2.7	-2.6	-2.3	-1.9	-2.1	-2.6	-2.6
Medication for cholesterol, blood pressure or diabetes	1.5	2.4	4.8	1.3	1.6	1.5	2.2	1.7	1.5	1.5	1.3	1.9	1.9	2.0	1.1	1.2	1.2	1.2	1.8	1.2	2.0	1.3	1.7	1.6	1.2
Whole body fat mass	1.5	6.1	10.4	-2.4	-2.7	-2.4	-2.6	-2.7	-2.0	-2.6	-2.2	-2.9	-3.2	-2.4	-2.7	-1.5	-2.4	-2.4	-2.7	-2.4	-2.4	-1.8	-2.2	-2.6	-2.4
Leg fat mass (right)	1.5	5.9	10.4	-2.2	-2.6	-2.3	-2.8	-2.6	-2.1	-2.4	-2.2	-3.0	-3.2	-2.6	-2.5	-1.8	-2.1	-2.1	-2.7	-2.1	-2.5	-1.6	-2.4	-2.6	-2.1
Age at First Birth	1.4	2.1	3.3	-1.2	-1.6	-1.4	-1.6	-1.2	-1.5	-1.4	-1.1	-1.7	-1.6	-1.7	-1.5	-1.8	-1.2	-1.2	-1.7	-1.2	-1.5	-1.1	-1.7	-1.4	-1.2
Blood White Count	1.4	10.7	30.0	-0.9	-2.7	-2.5	-4.4	-0.9	-3.9	-1.1	-2.8	-4.3	-5.0	-4.2	-3.7	-4.8	-0.4	-0.4	-3.7	-0.4	-3.9	-2.2	-5.5	-3.6	-0.4
Height	1.4	26.5	78.3	3.2	4.5	4.3	3.8	0.8	6.9	2.7	5.8	5.3	5.7	2.4	8.7	8.8	3.0	2.9	5.4	2.9	1.3	5.1	8.8	6.5	2.9
Medication for hormone replacement therapy	1.4	1.6	3.1	-1.2	-1.7	-1.3	-1.2	-0.6	-1.0	-1.0	-1.5	-1.5	-1.3	-1.8	-1.1	-1.6	-1.1	-1.1	-1.3	-1.1	-1.1	-0.5	-0.8	-1.5	-1.1
Trunk fat mass	1.4	6.0	10.2	-2.4	-2.7	-2.4	-2.6	-2.8	-1.9	-2.6	-2.1	-2.9	-3.2	-2.5	-2.6	-1.5	-2.3	-2.4	-2.7	-2.4	-2.6	-1.6	-2.1	-2.6	-2.4
Waist circumference	1.4	5.2	8.0	-2.4	-2.3	-2.3	-2.4	-2.7	-1.9	-2.6	-1.8	-2.8	-2.8	-2.0	-2.1	-1.3	-2.3	-2.3	-2.6	-2.3	-2.5	-1.6	-1.8	-2.3	-2.3
Had menopause	1.4	1.8	3.4	-1.4	-1.0	-1.1	-1.3	-1.9	-1.5	-1.7	-0.5	-1.1	-1.0	-1.7	-0.6	-0.9	-1.5	-1.5	-1.5	-1.5	-1.1	-1.7	-1.5	-0.7	-1.5
Illnesses of father: None of the above (group 1)	1.4	1.8	3.4	-1.2	-1.4	-1.4	-1.4	-0.9	-1.5	-1.1	-1.3	-1.7	-1.6	-0.7	-1.3	-1.8	-1.1	-1.1	-1.6	-1.1	-1.5	-1.1	-1.5	-1.3	-1.1
Arm fat mass (left)	1.4	5.6	8.4	-2.4	-2.5	-2.4	-2.5	-2.7	-2.0	-2.6	-2.1	-2.8	-2.9	-2.3	-2.3	-1.4	-2.4	-2.4	-2.6	-2.4	-2.2	-1.7	-2.0	-2.5	-2.4
Blood Red Count	1.3	12.1	31.2	5.1	2.4	3.7	1.6	5.6	2.1	5.0	2.7	1.8	0.8	1.1	-0.1	-1.3	5.4	5.4	2.0	5.4	2.0	3.4	-0.6	2.1	5.4
Qualifications: A levels/AS levels or equivalent	1.3	2.8	8.2	1.0	1.4	1.2	1.8	0.7	2.0	1.0	1.5	1.7	1.9	2.3	2.2	2.9	0.9	0.9	1.8	0.9	1.2	1.4	2.9	1.7	0.9
Guilty feelings	1.3	1.9	6.1	-0.5	-0.9	-1.1	-1.6	-1.0	-1.9	-0.8	-0.8	-1.8	-2.0	-1.1	-1.3	-1.7	-0.4	-0.4	-1.7	-0.4	-2.5	-1.4	-2.2	-1.3	-0.4
Coronary Artery Disease (CAD)	1.2	1.4	5.2	-0.8	-1.3	-1.1	-1.0	-0.2	-1.2	-0.6	-1.5	-1.1	-1.5	-0.5	-2.3	-1.9	-0.8	-0.8	-1.1	-0.8	-0.5	-1.1	-1.6	-1.5	-0.8
HbA1C	1.2	1.3	6.1	-0.7	1.6	-0.8	0.8	2.5	1.7	0.5	1.7	-1.0	1.2	0.7	1.5	-0.1	-0.6	-0.6	-0.3	-0.6	1.3	1.8	1.0	0.8	-0.6
Sensitivity / hurt feelings	1.2	2.1	3.5	-1.7	-1.5	-1.6	-0.6	-1.2	-1.4	-1.5	-1.5	-1.5	-1.0	-1.6	-1.9	-1.4	-1.7	-1.7	-1.3	-1.7	-0.4	-0.9	-1.0	-1.8	-1.7
Mean time to correctly identify matches	1.2	2.2	10.7	0.1	0.4	1.0	1.7	-0.6	2.1	-0.1	1.5	1.1	1.4	1.5	1.5	3.1	-0.1	-0.1	1.3	-0.1	1.5	2.0	3.3	1.3	-0.1
Mother’s age at death	1.2	1.5	3.3	-1.3	-1.2	-1.2	-1.8	-1.4	-1.0	-1.3	-1.4	-1.1	-1.2	-1.1	-0.1	-0.6	-1.3	-1.3	-1.2	-1.3	-1.3	-1.3	-1.1	-1.0	-1.3
High cholesterol (Self-reported)	1.2	2.1	5.5	-0.7	-1.8	-1.2	-2.3	-0.9	-1.4	-0.9	-1.2	-1.9	-2.1	-2.0	-1.2	-1.7	-0.6	-0.6	-1.6	-0.6	-2.1	-0.9	-1.8	-1.4	-0.6
Medication: Bendroflumethiazide	1.2	1.8	5.4	-1.1	-1.1	-1.3	-2.1	-1.7	-1.1	-1.4	-0.8	-1.8	-1.6	-1.6	-0.2	-0.7	-1.0	-1.1	-1.6	-1.1	-2.3	-1.1	-1.3	-1.1	-1.1
Commuting to job workplace: Cycle	1.2	1.5	2.5	-1.4	-1.5	-1.2	-0.9	-1.6	-1.1	-1.4	-1.3	-0.8	-1.4	-0.1	-1.4	-0.3	-1.4	-1.4	-1.0	-1.4	-0.5	-1.6	-0.9	-1.1	-1.4
Mean Putamen Volume	1.1	1.2	3.2	-1.2	-0.7	-1.3	-0.9	-0.8	-1.3	-1.0	-1.4	-0.8	-1.0	-1.2	-1.1	-0.9	-1.1	-1.1	-0.9	-1.1	-0.9	-1.8	-1.3	-1.0	-1.1
Average weekly fortified wine intake	1.1	1.3	2.6	-1.5	-1.0	-1.2	0.0	-1.6	-0.9	-1.5	-0.9	-0.8	-0.9	-0.4	-1.3	-0.1	-1.6	-1.6	-0.9	-1.6	-0.4	-1.2	-0.3	-1.2	-1.6
Fed-up feelings	1.1	2.1	6.1	-0.2	-1.0	-0.9	-1.9	-0.7	-1.5	-0.5	-0.7	-2.0	-2.1	-2.4	-1.0	-2.2	-0.0	-0.1	-1.7	-0.1	-2.5	-0.7	-2.3	-1.4	-0.1
Neuroticism score	1.1	2.3	5.5	-0.9	-1.2	-1.4	-2.0	-1.4	-2.0	-1.1	-1.1	-2.1	-2.1	-1.8	-0.9	-1.5	-0.7	-0.8	-1.8	-0.8	-2.3	-1.3	-2.1	-1.7	-0.8
Breastfed as a baby	1.1	1.3	2.7	0.9	0.8	1.1	1.6	0.7	1.4	0.8	1.4	1.0	1.2	1.5	0.5	1.5	0.8	0.8	1.1	0.8	1.4	1.4	1.7	0.9	0.8
Loud music exposure frequency	1.1	1.1	2.7	-0.8	-0.8	-1.1	-1.1	-0.8	-1.4	-0.7	-1.1	-1.3	-1.5	-1.1	-1.4	-1.3	-0.6	-0.6	-1.1	-0.6	-1.6	-0.9	-1.1	-1.0	-0.6
High blood pressure (siblings)	1.1	1.6	2.7	1.6	1.6	1.5	1.4	1.0	0.8	1.3	1.5	1.2	0.8	0.8	0.4	1.3	1.6	1.6	1.1	1.6	1.2	0.9	0.5	1.5	1.6
Exposure to tobacco smoke outside home	1.1	1.5	2.7	1.5	1.4	1.2	1.0	1.3	1.1	1.5	1.0	0.8	0.8	0.9	1.1	0.9	1.6	1.6	1.1	1.6	0.4	1.6	1.1	0.8	1.6
Asthma (self-reported)	1.1	2.2	4.4	-1.9	-1.4	-1.6	-1.0	-2.1	-1.1	-2.0	-1.1	-1.5	-1.1	-1.4	-1.0	-0.6	-2.0	-2.0	-1.4	-2.0	-1.1	-0.8	-0.4	-1.2	-2.0
Medication: Gliclazide	1.1	1.3	2.7	1.0	1.1	1.2	1.4	0.5	1.2	0.8	1.6	1.1	1.3	1.4	0.8	1.2	1.0	1.0	1.0	1.0	1.0	1.2	1.3	1.1	1.0
Commuting to job workplace: Public transport	1.1	1.3	3.3	1.2	1.4	1.3	1.8	0.5	0.5	0.9	1.7	1.1	0.9	1.8	0.2	0.9	1.2	1.2	0.9	1.2	0.6	0.6	0.8	1.3	1.2
Age started oral contraceptive pill	1.1	1.3	2.3	-1.4	-1.1	-1.2	-1.1	-1.4	-1.0	-1.4	-1.0	-0.9	-1.0	-0.7	-0.9	-0.5	-1.4	-1.4	-1.1	-1.4	-0.9	-1.5	-0.9	-0.9	-1.4
Medication: Cholesterol lowering	1.0	1.6	4.3	-0.7	-1.3	-1.2	-2.1	-0.9	-1.3	-0.8	-1.2	-1.7	-1.8	-1.7	-1.0	-1.5	-0.5	-0.6	-1.4	-0.6	-1.7	-0.8	-1.6	-1.4	-0.6
Chronic bronchitis/emphysema (mother)	1.0	1.1	4.5	1.2	1.0	1.0	0.4	0.8	0.8	1.1	0.9	0.8	0.9	1.0	2.1	1.1	1.3	1.2	1.0	1.2	0.1	0.9	0.9	0.7	1.2
Supplements: Vitamin C	1.0	1.2	4.0	0.7	0.4	1.0	1.0	1.3	1.7	0.9	0.9	0.9	1.2	0.8	1.0	0.8	0.6	0.6	1.2	0.6	1.5	2.0	1.7	0.7	0.6
Smoking status: Previous	1.0	1.5	2.9	-1.4	-1.7	-1.2	-1.4	-1.7	-0.5	-1.5	-1.1	-1.0	-1.1	-0.9	-0.4	-0.2	-1.5	-1.5	-1.1	-1.5	-1.5	-1.0	-0.3	-0.8	-1.5
Pack years of smoking	1.0	1.4	3.4	-0.9	-0.8	-1.0	-0.9	-0.8	-1.4	-1.0	-0.8	-1.2	-1.2	-1.8	-1.9	-1.8	-0.9	-0.9	-1.4	-0.9	-0.8	-1.2	-1.7	-1.0	-0.9
Major Depression (MDD)	0.9	1.1	2.0	-0.7	-1.1	-0.9	-1.3	-0.7	-0.9	-0.7	-1.3	-0.9	-1.2	-1.3	-0.9	-1.0	-0.7	-0.7	-0.9	-0.7	-1.0	-1.3	-1.4	-1.2	-0.7
Chronotype (morning person)	0.9	2.2	5.7	1.8	1.7	1.6	1.3	2.4	1.0	1.9	1.2	1.3	1.1	0.7	0.7	-0.0	1.9	1.9	1.1	1.9	1.9	1.2	-0.2	1.0	1.9
Number of treatments/medications taken	0.9	1.7	3.3	1.3	0.6	1.5	0.8	0.6	1.6	1.0	1.8	1.0	0.9	1.5	1.8	1.8	1.3	1.3	1.1	1.3	0.4	1.7	1.4	1.3	1.3
Had other major operations	0.9	1.1	3.2	0.9	1.1	0.8	1.1	0.4	0.9	0.8	1.0	1.1	1.0	1.2	1.6	1.8	0.9	0.9	1.0	0.9	0.6	0.5	1.4	1.3	0.9
Forced vital capacity (FVC)	0.9	3.6	10.6	1.5	1.7	1.6	0.9	1.5	2.5	1.7	1.4	2.3	2.2	0.4	3.2	2.5	1.4	1.4	2.3	1.4	0.7	1.6	2.7	2.4	1.4
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	8.3	1.3	1.6	1.4	1.0	1.5	2.2	1.6	1.1	2.2	2.1	0.4	2.9	2.1	1.3	1.3	2.2	1.3	0.9	1.3	2.4	1.9	1.3
Leg pain on walking	0.9	1.1	2.1	1.0	1.3	1.1	1.4	1.2	0.8	1.1	0.9	1.0	1.1	1.2	0.4	0.7	1.0	1.0	1.0	1.0	1.3	1.0	0.8	0.8	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	4.8	-1.5	-1.9	-1.5	-2.2	-1.6	-0.5	-1.4	-1.4	-1.5	-1.2	-1.6	0.3	-0.2	-1.4	-1.4	-1.0	-1.4	-2.0	-0.3	0.2	-1.2	-1.4
Ever had bowel cancer screening	0.9	1.1	3.5	0.7	1.1	0.7	1.1	0.0	0.8	0.5	1.3	0.9	1.3	1.2	1.9	1.9	0.7	0.7	1.0	0.7	-0.0	0.5	1.5	0.9	0.7
Illnesses of father: High blood pressure	0.9	1.1	2.2	1.1	1.1	1.2	0.4	0.6	1.1	0.9	1.5	1.0	1.4	0.5	1.2	0.9	1.1	1.1	1.0	1.1	0.5	1.0	0.8	1.4	1.1
Respiratory disease	0.8	1.9	3.3	-1.8	-1.3	-1.5	-0.8	-1.8	-1.1	-1.8	-1.1	-1.5	-1.1	-1.0	-1.4	-0.6	-1.8	-1.8	-1.3	-1.8	-0.9	-0.8	-0.5	-1.3	-1.8
Impedance of leg (right)	0.8	3.9	9.3	2.9	1.5	2.0	0.8	2.8	1.3	2.8	1.4	1.3	1.1	1.1	1.4	0.1	3.0	3.0	1.6	3.0	0.6	1.7	0.4	1.4	3.0
Number of incorrect matches in round	0.8	1.4	2.2	-1.1	-1.3	-1.1	-1.1	-1.4	-1.2	-1.3	-1.0	-1.1	-1.3	-0.6	-0.8	-0.7	-1.2	-1.2	-1.2	-1.2	-1.5	-1.5	-1.3	-1.2	-1.2
Pain all over the body in last month	0.8	0.8	1.4	1.1	1.2	1.1	0.7	0.7	0.5	0.9	1.2	0.8	0.9	0.4	1.0	0.7	1.1	1.1	0.7	1.1	0.8	0.8	0.2	0.9	1.1
Weight	0.8	4.1	7.9	-2.3	-2.1	-2.1	-2.3	-2.8	-1.1	-2.5	-1.6	-2.2	-2.2	-2.4	-1.1	-0.3	-2.3	-2.4	-2.0	-2.4	-2.3	-1.2	-0.7	-1.7	-2.4
Asthma	0.8	1.5	3.3	-1.6	-1.1	-1.3	-0.7	-1.8	-0.8	-1.7	-0.7	-1.3	-0.8	-1.2	-0.8	-0.4	-1.7	-1.7	-1.1	-1.7	-0.7	-0.5	-0.1	-1.0	-1.7
Hair/balding pattern: Pattern 4	0.8	2.1	3.6	-1.2	-1.2	-1.4	-1.6	-1.2	-1.7	-1.3	-1.6	-1.4	-1.4	-1.1	-1.2	-1.8	-1.2	-1.2	-1.6	-1.2	-1.5	-1.7	-1.9	-1.5	-1.2
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	3.0	-0.9	-0.8	-1.1	-1.4	-0.8	-1.0	-0.8	-1.1	-1.2	-1.2	-1.3	-0.5	-1.1	-0.8	-0.8	-1.0	-0.8	-1.7	-0.8	-0.8	-1.0	-0.8
Knee pain experienced in last month	0.8	1.2	2.5	-1.3	-0.8	-1.3	-1.0	-1.4	-1.2	-1.3	-0.8	-1.2	-1.0	-0.5	-0.3	-0.4	-1.3	-1.3	-1.1	-1.3	-1.6	-1.2	-0.7	-0.9	-1.3
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.5	-1.1	-0.9	-1.0	-1.0	-1.6	-0.8	-1.3	-0.5	-1.1	-0.9	-0.7	-0.6	-0.2	-1.2	-1.2	-1.2	-1.2	-1.0	-0.8	-0.6	-0.6	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.4	-1.5	-1.4	-1.2	-1.0	-1.8	-0.3	-1.6	-0.8	-1.1	-1.0	-0.1	-0.3	0.6	-1.6	-1.6	-0.9	-1.6	-1.2	-0.6	0.4	-0.7	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.6	4.8	1.0	1.4	1.2	1.2	0.7	1.1	1.0	1.1	1.6	1.4	1.1	2.2	2.1	1.0	1.0	1.5	1.0	1.0	0.7	1.4	1.5	1.0
Alcohol drinker status: Previous	0.8	0.9	2.6	-0.6	-0.9	-1.0	-1.1	-0.2	-1.2	-0.5	-1.6	-1.0	-1.2	-0.8	-0.9	-1.4	-0.5	-0.5	-1.0	-0.5	-0.7	-1.0	-1.4	-1.1	-0.5
Worry (Nagel 2018)	0.7	1.4	2.5	-1.3	-1.1	-1.3	-1.4	-1.6	-1.2	-1.4	-0.8	-1.5	-1.2	-1.1	-0.3	-0.3	-1.3	-1.3	-1.3	-1.3	-1.4	-0.8	-0.8	-1.2	-1.3
Alzheimer’s Disease (in father)	0.7	0.7	2.5	0.5	0.7	0.7	1.4	0.8	0.9	0.7	0.4	1.1	1.1	1.1	0.1	0.9	0.4	0.4	1.0	0.4	1.6	0.8	1.1	0.6	0.4
Neuroticism	0.7	1.6	5.8	-0.4	-0.8	-1.0	-1.8	-1.0	-1.6	-0.7	-0.8	-1.8	-1.8	-1.6	-0.4	-1.3	-0.2	-0.3	-1.5	-0.3	-2.4	-1.0	-1.8	-1.3	-0.3
Past tobacco smoking	0.7	1.3	2.6	1.3	1.6	1.2	1.5	1.6	0.7	1.4	1.1	1.1	1.1	0.7	0.3	0.3	1.3	1.3	1.1	1.3	1.6	1.1	0.5	0.8	1.3
Hair/balding pattern: Pattern 3	0.7	1.1	2.4	1.4	1.3	1.1	1.0	1.4	0.4	1.4	1.2	0.6	0.5	0.8	0.4	0.0	1.5	1.5	0.7	1.5	0.1	0.7	-0.1	0.8	1.5
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.2	0.8	0.7	0.6	0.9	1.1	0.9	1.0	0.6	0.7	0.7	1.5	0.5	0.8	0.8	0.8	1.0	0.8	0.8	1.1	1.2	0.5	0.8
Lung cancer (father)	0.7	0.8	2.0	-0.7	-1.1	-0.6	-0.7	-0.8	-0.8	-0.9	-0.7	-0.9	-1.0	-1.4	-1.3	-1.0	-0.7	-0.7	-1.0	-0.7	-0.5	-0.6	-1.1	-1.1	-0.7
Birth weight of first child	0.7	1.3	2.3	1.1	1.1	1.0	1.1	1.1	1.2	1.2	1.1	1.1	1.5	0.7	1.4	0.7	1.1	1.1	1.2	1.1	0.6	1.2	1.4	1.0	1.1
Medication: Amlodipine	0.7	1.0	2.3	0.9	0.6	1.1	0.4	0.1	1.4	0.6	1.5	0.7	0.8	-0.0	1.4	1.5	0.8	0.8	0.8	0.8	0.5	1.5	1.3	1.1	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	2.0	1.0	0.9	0.7	0.8	1.4	0.8	1.2	0.5	0.8	0.8	0.7	0.7	0.2	1.1	1.1	0.9	1.1	0.6	0.7	0.8	0.7	1.1
Qualifications: nursing, teaching	0.7	1.1	3.3	-1.4	-0.9	-1.1	-0.8	-1.8	-0.4	-1.5	-0.5	-1.0	-0.5	-1.1	0.0	0.5	-1.5	-1.5	-0.9	-1.5	-0.7	-0.4	0.4	-0.7	-1.5
Osteoporosis (self-reported)	0.7	0.9	1.6	-0.9	-0.8	-1.0	-1.3	-0.7	-1.0	-0.9	-0.9	-1.1	-0.8	-1.2	-0.4	-1.0	-0.9	-0.9	-1.0	-0.9	-0.7	-0.7	-1.1	-1.3	-0.9
Breast Cancer	0.6	1.5	3.7	-0.8	-1.3	-1.1	-1.2	-0.2	-1.4	-0.6	-1.5	-1.1	-1.3	-1.2	-1.5	-1.9	-0.7	-0.7	-1.3	-0.7	-0.8	-1.4	-1.9	-1.4	-0.7
Fasting Glucose	0.6	0.7	1.3	1.1	-0.8	1.1	-0.6	-1.0	-0.7	0.3	-0.8	0.9	-0.7	0.2	-0.8	0.7	1.1	1.1	0.5	1.1	-0.0	-0.7	-0.7	-0.4	1.1
Neuroticism (2016)	0.6	0.9	3.7	-0.2	-0.6	-0.6	-1.3	-0.8	-1.1	-0.5	-0.7	-0.9	-0.7	-1.8	0.0	-1.4	-0.2	-0.2	-1.0	-0.2	-1.9	-0.9	-1.4	-0.8	-0.2
Blood Platelet Count	0.6	6.7	11.5	-3.2	-2.8	-2.8	-1.6	-2.4	-2.1	-2.9	-2.9	-2.4	-2.2	-1.8	-3.2	-1.8	-3.2	-3.2	-2.2	-3.2	-0.1	-1.7	-1.8	-3.4	-3.2
Cardiovascular Disease	0.6	2.0	4.9	-1.0	-2.2	-1.2	-2.2	-1.1	-0.9	-1.0	-1.6	-1.7	-2.1	-1.4	-1.5	-1.2	-0.9	-0.9	-1.5	-0.9	-1.6	-0.8	-1.4	-1.7	-0.9
Tanning	0.6	7.4	10.7	-2.6	-2.3	-2.7	-2.1	-2.5	-3.3	-2.7	-2.3	-3.1	-3.0	-2.1	-3.1	-2.9	-2.6	-2.6	-3.2	-2.6	-2.4	-2.8	-3.3	-2.8	-2.6
Hearing difficulty/problems: Yes	0.6	0.9	2.9	-0.4	-0.5	-0.9	-1.0	-0.4	-1.5	-0.4	-1.2	-0.8	-1.4	-0.3	-0.8	-1.0	-0.3	-0.3	-0.9	-0.3	-1.5	-1.7	-1.6	-1.0	-0.3
Supplements: Zinc	0.6	0.7	2.4	0.3	0.5	0.6	1.6	0.8	1.0	0.5	0.3	1.1	0.7	1.2	-0.1	0.9	0.2	0.2	1.0	0.2	1.4	0.7	1.4	0.6	0.2
Pack years adult smoking proportion	0.6	0.9	3.1	-0.5	-0.6	-0.7	-0.7	-0.3	-1.1	-0.5	-0.7	-0.9	-1.0	-1.4	-1.7	-1.8	-0.5	-0.5	-1.0	-0.5	-0.5	-0.9	-1.5	-0.8	-0.5
High blood pressure	0.6	1.6	3.6	-1.1	-1.5	-1.1	-1.6	-1.8	-0.9	-1.4	-0.9	-1.5	-1.6	-0.9	-0.7	-0.4	-1.1	-1.1	-1.4	-1.1	-1.9	-1.1	-1.0	-1.2	-1.1
Pulse wave Arterial Stiffness index	0.6	0.7	1.7	-1.1	-1.1	-0.7	-0.7	-1.3	0.1	-1.1	-0.6	-0.7	-0.5	-0.3	0.1	0.5	-1.2	-1.2	-0.5	-1.2	-0.7	0.2	0.8	-0.4	-1.2
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.7	-0.6	-0.9	-0.7	-0.8	-0.5	-0.8	-0.6	-0.9	-1.1	-1.2	-1.0	-1.3	-1.0	-0.6	-0.6	-0.9	-0.6	-0.6	-0.3	-1.0	-1.1	-0.6
Pulse rate, automated reading	0.6	2.1	4.3	1.4	1.8	1.4	1.8	0.4	1.3	1.1	2.0	1.4	1.1	1.1	1.4	2.1	1.4	1.4	1.4	1.4	0.1	0.8	1.7	1.9	1.4
Alcohol intake frequency.	0.6	1.5	8.4	0.3	-0.1	-0.2	-0.7	1.3	-1.3	0.5	-0.8	-0.7	-1.1	-1.6	-2.1	-2.9	0.4	0.4	-0.9	0.4	0.4	-0.7	-2.7	-1.0	0.4
Diabetes diagnosed by doctor	0.6	1.0	3.6	0.9	1.2	1.2	1.2	0.5	1.1	0.6	1.9	0.7	1.2	0.9	1.0	1.0	0.8	0.8	0.6	0.8	0.9	1.2	0.9	1.2	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.0	0.6	0.7	0.9	1.0	0.1	0.9	0.4	1.1	1.1	0.9	0.9	0.7	1.2	0.5	0.5	0.8	0.5	0.5	0.4	1.1	1.4	0.5
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.4	-1.1	-1.2	-0.8	-0.6	-1.1	-0.6	-1.1	-0.6	-0.7	-0.8	-0.9	-1.1	-0.6	-1.2	-1.2	-0.9	-1.2	-0.4	-0.8	-0.6	-0.7	-1.2
Verbal and Numeric Reasoning (VNR)	0.5	1.1	4.5	0.5	0.5	0.8	0.2	-0.2	1.6	0.3	1.1	0.6	0.9	-0.2	2.1	2.0	0.4	0.4	0.8	0.4	0.3	1.8	1.9	1.0	0.4
Taking other prescription medications	0.5	0.8	3.1	0.9	1.1	0.9	0.9	0.1	0.5	0.5	1.8	0.5	0.8	0.7	1.4	1.3	0.9	0.8	0.5	0.8	0.4	0.8	0.6	1.2	0.8
Stomach or abdominal pain in last month	0.5	0.7	2.8	0.2	-0.1	0.4	0.5	0.8	1.5	0.5	0.5	0.3	0.9	1.1	0.6	1.0	0.2	0.2	0.7	0.2	1.4	1.6	1.7	-0.0	0.2
Standing height	0.5	4.7	20.2	0.8	1.5	1.3	0.7	-0.3	3.2	0.7	2.1	2.1	2.4	0.0	4.5	4.1	0.7	0.7	2.2	0.7	-0.7	1.9	4.3	2.7	0.7
Age at first live birth	0.5	0.8	2.1	-1.1	-0.8	-0.9	-0.8	-1.4	-0.8	-1.2	-0.6	-0.7	-0.3	-0.1	0.2	-0.2	-1.1	-1.1	-0.8	-1.1	-1.4	-1.3	-0.3	-0.6	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.5	0.1	-0.4	-0.4	-0.4	0.7	-0.8	0.3	-1.1	-0.4	-0.9	-0.7	-1.6	-1.6	0.2	0.2	-0.5	0.2	-0.1	-0.6	-1.3	-0.7	0.2
Medication: Blood pressure	0.5	1.0	2.4	1.2	0.7	1.1	0.7	0.3	1.0	0.8	1.6	0.4	0.2	0.9	0.7	1.3	1.3	1.2	0.6	1.2	-0.0	1.3	0.8	1.1	1.2
Heart disease (siblings)	0.5	0.6	2.6	-0.5	-0.5	-0.6	-0.4	-0.6	-1.1	-0.6	-0.2	-0.9	-1.1	-0.3	-1.6	-1.0	-0.4	-0.4	-0.9	-0.4	-0.8	-0.8	-1.1	-0.3	-0.4
Bipolar Disorder (2018)	0.4	0.7	2.4	0.7	1.0	0.8	1.1	0.1	0.6	0.5	1.2	0.5	0.7	1.6	0.9	1.3	0.7	0.7	0.6	0.7	0.2	0.7	1.0	0.8	0.7
Depressed Affect (Nagel 2018)	0.4	0.7	3.8	0.7	0.2	0.0	-1.2	0.1	-0.6	0.4	0.2	-1.0	-1.0	-1.2	0.7	-0.7	0.9	0.9	-0.6	0.9	-1.9	-0.0	-1.2	-0.5	0.9
Neuroticism (Nagel 2018)	0.4	1.0	4.6	-0.6	-0.6	-0.9	-1.3	-1.2	-1.1	-0.8	-0.4	-1.5	-1.2	-1.1	0.1	-0.6	-0.5	-0.5	-1.2	-0.5	-2.1	-0.7	-1.0	-1.0	-0.5
Irritable Bowel Disease (IBD)	0.4	0.9	2.2	0.9	0.9	0.9	0.8	1.3	1.0	1.0	0.8	0.6	1.0	0.7	0.8	0.6	0.9	0.9	0.8	0.9	1.4	1.5	0.9	0.5	0.9
Prostate Cancer	0.4	0.5	1.6	-0.9	-0.4	-0.7	-0.5	-1.3	-0.5	-1.0	-0.4	-0.5	-0.4	-0.3	-0.3	0.2	-1.0	-1.0	-0.5	-1.0	-0.9	-0.8	0.1	-0.3	-1.0
HDL Cholesterol	0.4	0.6	2.3	-0.8	-0.3	-0.8	-0.4	-1.5	-1.0	-1.0	-0.3	-0.9	-0.6	-0.5	-0.4	-0.1	-0.7	-0.7	-0.8	-0.7	-1.5	-0.9	-0.5	-0.7	-0.7
Hypothyroidism (self reported)	0.4	0.8	1.9	1.1	0.9	1.1	0.7	1.4	0.8	1.2	0.7	0.9	0.8	0.4	0.3	0.1	1.1	1.1	0.9	1.1	1.3	0.9	0.2	0.7	1.1
Ever had hysterectomy (womb removed)	0.4	0.4	0.9	0.8	0.8	0.8	0.6	0.5	0.5	0.7	0.9	0.5	0.5	-0.0	0.5	0.5	0.8	0.8	0.5	0.8	0.2	0.5	0.3	0.9	0.8
Leg fat-free mass (left)	0.4	1.9	5.8	-1.9	-1.0	-1.3	-1.1	-2.4	0.0	-2.0	-0.6	-0.8	-0.6	-1.5	0.4	1.2	-2.0	-2.0	-0.8	-2.0	-1.4	-0.6	0.9	-0.5	-2.0
Hand grip strength (right)	0.4	1.1	3.6	-1.0	-1.0	-1.4	-1.7	-0.4	-0.6	-0.7	-1.5	-1.0	-0.7	-1.9	0.0	-1.0	-0.9	-0.9	-0.6	-0.9	-1.5	-0.7	-0.3	-1.1	-0.9
Maternal smoking around birth	0.4	0.5	2.2	-0.3	-0.3	-0.6	-1.0	-0.5	-1.0	-0.4	-0.5	-0.9	-0.8	-0.7	-0.1	-1.0	-0.2	-0.2	-0.8	-0.2	-1.5	-0.9	-1.2	-0.6	-0.2
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.1	-0.3	-0.7	-0.4	-0.9	-0.4	-0.7	-0.4	-0.7	-0.6	-0.9	-0.6	-0.9	-1.0	-0.3	-0.3	-0.6	-0.3	-0.9	-0.7	-1.0	-0.8	-0.3
Qualifications: CSEs or equivalent	0.4	0.5	2.8	-0.0	-0.4	-0.5	-0.9	0.8	-0.6	0.2	-1.0	-0.7	-0.9	-0.7	-1.1	-1.7	0.1	0.1	-0.5	0.1	-0.2	-0.2	-1.3	-0.9	0.1
Impedance of leg (left)	0.4	2.0	5.7	2.2	0.9	1.3	0.2	2.3	0.6	2.2	0.7	0.6	0.3	0.8	0.5	-0.5	2.4	2.4	0.9	2.4	0.2	1.2	-0.2	0.8	2.4
Leg predicted mass (left)	0.4	2.0	5.9	-1.9	-1.0	-1.3	-1.1	-2.4	-0.0	-2.0	-0.7	-0.9	-0.6	-1.6	0.4	1.1	-2.0	-2.0	-0.8	-2.0	-1.4	-0.6	0.8	-0.6	-2.0
Hair/balding pattern: Pattern 2	0.4	0.5	1.0	-0.9	-0.9	-0.6	-0.2	-0.8	-0.1	-0.9	-0.7	-0.6	-0.4	-0.3	-0.9	-0.0	-1.0	-1.0	-0.5	-1.0	0.8	0.1	0.1	-0.9	-1.0
Financial difficulties in last 2 years	0.4	0.5	1.3	-0.5	-0.9	-0.9	-1.0	0.1	-0.6	-0.3	-1.1	-1.0	-1.0	-0.3	-1.1	-1.2	-0.4	-0.4	-0.6	-0.4	-0.7	-0.1	-0.4	-1.0	-0.4
Medication: Simvastatin	0.4	0.6	1.6	1.1	0.4	1.0	0.5	0.7	0.8	0.8	1.1	0.4	0.3	0.3	0.2	0.2	1.1	1.1	0.5	1.1	0.4	1.3	0.4	0.6	1.1
Pulse rate	0.4	0.7	1.7	0.8	1.3	0.6	1.1	0.4	0.4	0.8	0.9	0.9	0.5	1.1	0.8	1.2	0.9	0.9	0.8	0.9	0.0	-0.2	0.8	1.0	0.9
Prospective memory result	0.4	0.4	2.4	-0.1	-0.5	-0.4	-0.3	0.0	-0.9	-0.0	-0.8	-0.5	-1.0	0.1	-1.5	-1.0	0.0	0.0	-0.5	0.0	-0.3	-1.0	-1.2	-0.7	0.0
Peak expiratory flow (PEF)	0.4	1.0	2.4	-1.2	-1.4	-1.1	-1.4	-1.0	-0.3	-1.0	-1.6	-0.4	-0.8	-1.2	-0.2	-0.1	-1.2	-1.2	-0.5	-1.2	-1.0	-1.1	-0.3	-0.9	-1.2
Pulse wave peak to peak time	0.4	0.5	1.2	0.9	1.1	0.7	0.5	1.1	-0.0	1.0	0.6	0.7	0.5	0.0	0.1	-0.3	1.0	1.0	0.5	1.0	0.6	-0.2	-0.6	0.5	1.0
Medication for pain relief, constipation, heartburn	0.4	0.7	2.4	-1.0	-0.7	-0.9	-0.1	-0.3	-0.7	-0.7	-1.3	-0.1	-0.3	-0.9	-1.6	-1.0	-1.1	-1.1	-0.3	-1.1	0.7	-1.0	-0.5	-0.8	-1.1
Chest pain or discomfort	0.4	0.6	1.0	0.9	0.7	0.8	0.8	0.6	0.7	0.8	1.0	0.6	0.5	0.7	0.5	0.8	0.9	0.9	0.7	0.9	0.3	0.9	0.8	0.7	0.9
Age at last live birth	0.4	0.6	1.4	-1.1	-0.7	-0.8	-0.9	-1.1	-0.3	-1.1	-0.6	-0.5	-0.1	-0.2	0.6	0.0	-1.2	-1.2	-0.5	-1.2	-0.9	-0.6	0.1	-0.5	-1.2
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	2.0	-0.7	-0.2	-0.4	-0.5	-1.4	-0.5	-1.0	-0.2	0.0	-0.2	-0.7	0.2	0.5	-0.8	-0.8	-0.4	-0.8	-0.8	-1.4	-0.3	0.2	-0.8
Hypertension (Self-reported)	0.4	1.2	3.3	-0.9	-1.4	-0.9	-1.6	-1.6	-0.7	-1.2	-0.6	-1.3	-1.5	-0.8	-0.6	-0.2	-0.9	-0.9	-1.2	-0.9	-1.8	-0.8	-0.9	-1.0	-0.9
Leg fat-free mass (right)	0.4	2.2	6.2	-2.0	-1.0	-1.4	-1.1	-2.5	-0.0	-2.1	-0.7	-0.9	-0.6	-1.4	0.3	1.1	-2.2	-2.2	-0.8	-2.2	-1.4	-0.6	0.9	-0.6	-2.2
Average weekly red wine intake	0.4	0.6	2.2	0.1	1.0	0.4	1.1	-0.4	0.8	-0.0	0.9	0.8	1.1	0.5	1.0	1.5	-0.0	-0.0	0.8	-0.0	0.6	0.5	1.5	0.8	-0.0
Mood swings	0.4	0.7	2.6	0.1	-0.5	-0.5	-1.2	-0.3	-0.8	-0.1	-0.4	-1.2	-1.2	-1.6	-0.2	-1.0	0.2	0.2	-0.9	0.2	-1.5	-0.2	-1.2	-0.8	0.2
Friendships satisfaction	0.4	0.5	2.0	0.1	0.4	0.4	0.5	0.3	1.2	0.2	0.6	0.7	1.0	0.4	1.1	1.1	0.1	0.1	0.8	0.1	0.6	0.9	1.4	0.7	0.1
Leg predicted mass (right)	0.4	2.0	5.9	-2.0	-0.9	-1.3	-1.0	-2.4	0.1	-2.0	-0.6	-0.8	-0.5	-1.3	0.4	1.2	-2.1	-2.1	-0.7	-2.1	-1.3	-0.5	1.0	-0.5	-2.1
Ever smoked	0.4	0.7	1.3	-0.8	-1.0	-0.9	-1.1	-1.0	-0.8	-0.8	-1.0	-0.6	-0.8	-0.8	-0.4	-0.5	-0.8	-0.8	-0.7	-0.8	-1.1	-1.1	-0.8	-0.7	-0.8
Impedance of whole body	0.4	2.1	5.1	2.1	1.1	1.6	1.1	2.2	0.9	2.0	1.1	1.1	0.8	1.3	0.3	-0.3	2.1	2.2	1.1	2.2	0.8	1.1	-0.1	0.9	2.2
Ulcerative Colitis (UC)	0.3	0.6	1.7	0.5	0.7	0.6	0.7	0.7	0.8	0.6	0.5	0.6	1.0	1.1	1.0	1.1	0.4	0.4	0.8	0.4	1.3	1.0	1.1	0.5	0.4
Body Mass Index (BMI) (2010)	0.3	0.5	1.3	-0.7	-0.7	-0.6	-0.1	-0.7	-0.8	-0.7	-0.8	-0.2	-0.5	-0.3	-1.1	-0.5	-0.8	-0.8	-0.6	-0.8	0.1	-1.0	-0.8	-0.7	-0.8
Ulcerative Colitis	0.3	0.4	1.4	0.3	0.6	0.4	0.5	0.3	0.8	0.4	0.5	0.3	0.7	0.8	1.0	1.1	0.3	0.3	0.6	0.3	0.6	0.9	1.2	0.4	0.3
Smoking Status	0.3	0.6	2.1	-0.7	-0.7	-0.8	-0.9	-1.1	-1.0	-0.8	-0.6	-0.9	-1.1	-0.0	-0.3	-0.1	-0.6	-0.6	-0.9	-0.6	-1.4	-1.1	-0.6	-0.3	-0.6
Hand grip strength (left)	0.3	0.8	3.5	-0.8	-0.9	-1.1	-1.4	-0.2	-0.5	-0.4	-1.4	-0.6	-0.6	-1.9	-0.1	-0.9	-0.8	-0.8	-0.4	-0.8	-0.9	-0.7	-0.4	-1.0	-0.8
Current tobacco smoking	0.3	0.4	1.2	0.8	0.7	0.4	0.6	1.1	-0.4	0.9	0.1	0.1	-0.2	0.7	-0.6	-0.6	1.0	1.0	0.1	1.0	0.2	-0.1	-0.7	0.2	1.0
Relative age voice broke	0.3	0.5	1.3	0.9	0.8	0.6	0.9	1.1	-0.0	0.9	0.6	0.5	0.3	0.9	-0.6	-0.5	0.9	0.9	0.4	0.9	0.5	0.0	-0.5	0.1	0.9
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.8	0.0	0.3	0.3	0.1	-0.8	0.4	-0.3	1.2	0.1	0.4	0.1	1.1	1.3	-0.0	-0.1	0.1	-0.1	-0.1	0.5	0.8	0.9	-0.1
Supplements: Glucosamine	0.3	0.4	1.1	-0.8	-0.3	-0.4	0.3	-1.1	0.1	-0.9	0.0	-0.3	0.0	0.5	-0.1	0.8	-0.9	-0.9	-0.1	-0.9	0.1	0.2	1.0	-0.1	-0.9
Medication: Atenolol	0.3	0.4	2.4	-0.2	-0.1	-0.1	-1.2	-1.0	0.2	-0.5	0.3	-0.5	-0.2	-1.1	1.6	0.7	-0.2	-0.2	-0.3	-0.2	-1.1	0.6	0.3	0.2	-0.2
Allergy	0.3	0.6	1.2	1.1	1.0	1.0	0.8	1.0	0.6	1.0	0.8	0.9	0.6	0.5	0.0	0.0	1.1	1.1	0.6	1.1	0.7	0.3	-0.2	0.6	1.1
Fluid intelligence score	0.3	0.5	2.4	-0.8	-0.4	-0.4	-0.4	-1.5	0.2	-1.1	0.2	-0.6	-0.1	-0.8	0.8	1.2	-0.9	-0.9	-0.4	-0.9	-0.5	0.4	0.9	-0.2	-0.9
Trunk fat-free mass	0.3	1.7	8.4	-0.6	0.3	-0.2	-0.7	-1.5	1.4	-0.7	0.6	0.4	0.8	-1.2	2.9	2.8	-0.7	-0.7	0.6	-0.7	-1.2	0.7	2.6	1.1	-0.7
Time employed in main current job	0.3	0.3	0.7	-0.8	-0.4	-0.5	-0.1	-0.5	-0.3	-0.7	-0.4	-0.4	-0.1	-0.8	-0.6	-0.7	-0.8	-0.8	-0.4	-0.8	0.2	-0.2	-0.1	-0.7	-0.8
Father’s age at death	0.3	0.3	1.8	0.1	0.9	0.6	1.3	-0.3	0.1	-0.1	0.9	0.9	1.1	0.3	-0.1	0.4	-0.0	-0.0	0.5	-0.0	0.7	-0.2	0.2	0.7	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.1	1.0	0.2	0.9	-0.0	0.5	0.6	0.7	0.9	0.1	0.1	0.5	0.8	0.3	1.0	1.0	0.2	1.0	-0.2	1.0	0.0	0.2	1.0
Number of live births	0.3	0.5	1.1	-1.0	-0.3	-0.7	-0.5	-0.8	-0.4	-0.9	-0.4	-0.8	-0.4	-0.2	-0.2	-0.3	-1.0	-1.1	-0.7	-1.1	-0.6	-0.2	-0.1	-0.6	-1.1
Impedance of arm (left)	0.3	1.3	2.5	1.5	0.9	1.4	1.4	1.6	0.8	1.4	1.1	1.1	0.9	1.4	0.1	-0.1	1.4	1.5	0.9	1.5	1.0	0.7	-0.1	0.8	1.5
Trunk predicted mass	0.3	1.7	8.5	-0.5	0.4	-0.1	-0.6	-1.4	1.5	-0.7	0.6	0.5	0.8	-1.1	2.9	2.8	-0.6	-0.6	0.7	-0.6	-1.2	0.7	2.6	1.1	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.9	-0.6	-0.9	-0.8	-1.1	-0.0	-0.4	-0.3	-1.0	-1.0	-0.6	-1.1	0.1	-0.8	-0.5	-0.5	-0.6	-0.5	-0.7	0.1	-0.3	-1.4	-0.5
Arm fat-free mass (right)	0.3	1.5	4.2	-1.2	-0.6	-0.9	-1.5	-2.0	0.5	-1.4	-0.3	-0.6	-0.4	-1.8	1.8	1.8	-1.2	-1.3	-0.3	-1.3	-1.9	0.1	1.5	0.1	-1.3
Number of full brothers	0.3	0.3	0.9	0.5	0.4	0.6	0.8	0.7	0.5	0.6	0.5	0.7	0.6	0.7	0.1	0.4	0.5	0.5	0.7	0.5	1.0	0.3	0.3	0.6	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.2	-0.8	-1.1	-0.5	-0.5	-0.9	-0.2	-0.9	-0.4	-0.7	-0.5	-0.2	-0.3	0.1	-0.9	-0.9	-0.6	-0.9	0.2	0.1	-0.1	-0.8	-0.9
Health satisfaction	0.3	0.3	1.0	-0.8	-0.7	-0.7	-0.1	-0.3	0.1	-0.6	-0.8	-0.5	-0.3	0.1	-0.6	-0.0	-0.8	-0.8	-0.2	-0.8	0.3	0.2	0.5	-1.0	-0.8
Medication: Ibuprofen	0.3	0.3	3.4	0.2	0.1	-0.1	-0.7	-0.5	-0.7	-0.1	0.1	-0.5	-0.6	0.5	0.4	0.0	0.3	0.3	-0.4	0.3	-1.9	-0.8	-0.7	0.1	0.3
Medication: Allopurinol	0.3	0.4	1.3	0.3	0.8	0.5	0.9	0.1	0.6	0.2	0.7	0.8	0.7	1.0	0.7	1.1	0.2	0.2	0.6	0.2	0.4	0.2	1.0	0.9	0.2
Medication: Omeprazole	0.3	0.3	0.7	0.6	0.5	0.5	0.3	0.7	0.5	0.6	0.7	0.2	0.5	0.4	0.9	0.4	0.7	0.6	0.3	0.6	0.5	0.7	0.2	0.1	0.6
Arm predicted mass (right)	0.3	1.4	4.2	-1.1	-0.4	-0.9	-1.4	-2.0	0.4	-1.3	-0.2	-0.6	-0.3	-1.7	1.8	1.8	-1.1	-1.2	-0.3	-1.2	-1.9	-0.0	1.5	0.2	-1.2
Comparative height size at age 10	0.3	1.5	7.0	-0.9	0.0	-0.5	-1.2	-1.8	0.6	-1.1	0.1	0.2	0.3	-1.9	2.6	1.9	-0.9	-1.0	0.1	-1.0	-2.2	-0.6	1.4	0.9	-1.0
Whole body fat-free mass	0.3	1.5	4.3	-1.3	-0.4	-0.8	-1.0	-2.1	0.7	-1.4	-0.1	-0.3	0.0	-1.5	1.8	2.0	-1.4	-1.4	-0.1	-1.4	-1.5	0.1	1.8	0.3	-1.4
Loneliness, isolation	0.3	0.5	1.2	1.0	0.5	0.5	-0.4	0.6	0.2	0.8	0.4	-0.1	-0.2	-0.8	0.5	-0.3	1.1	1.1	0.1	1.1	-0.7	0.8	-0.2	0.2	1.1
Back pain experienced in last month	0.3	0.5	1.2	-0.5	-0.3	-0.7	-0.5	-0.4	-1.1	-0.5	-0.7	-0.7	-0.7	0.1	-0.8	-0.9	-0.5	-0.5	-0.8	-0.5	-0.7	-1.1	-1.1	-0.6	-0.5
Osteoarthritis (self-reported)	0.3	0.3	1.8	-0.4	-0.0	-0.4	-0.7	-1.3	-0.7	-0.7	0.2	-0.4	-0.3	-0.3	0.6	0.7	-0.4	-0.4	-0.4	-0.4	-0.9	-0.9	-0.4	-0.0	-0.4
Whole body water mass	0.3	1.7	4.8	-1.4	-0.5	-1.0	-1.1	-2.2	0.6	-1.5	-0.2	-0.4	-0.1	-1.6	1.7	2.0	-1.5	-1.5	-0.2	-1.5	-1.6	-0.0	1.8	0.1	-1.5
Average weekly champagne plus white wine intake	0.3	0.5	1.4	-0.9	-0.3	-0.5	0.3	-1.2	-0.4	-1.0	-0.1	0.1	-0.2	0.8	-0.3	0.7	-1.0	-1.0	-0.2	-1.0	-0.6	-1.1	0.3	0.1	-1.0
Miserableness	0.3	0.6	2.9	0.7	0.0	0.0	-1.1	0.1	-0.5	0.4	0.2	-0.8	-0.8	-1.0	0.4	-0.7	0.8	0.8	-0.5	0.8	-1.7	-0.0	-1.1	-0.4	0.8
Medication: Lisinopril	0.3	0.4	1.1	0.8	0.0	0.8	-0.1	1.1	1.1	0.8	0.4	0.6	0.5	-0.2	0.9	0.2	0.7	0.7	0.5	0.7	0.5	0.9	0.4	0.5	0.7
Basal metabolic rate	0.3	1.8	5.2	-1.6	-0.9	-1.2	-1.4	-2.3	0.3	-1.7	-0.6	-0.8	-0.6	-1.8	1.1	1.5	-1.7	-1.7	-0.6	-1.7	-1.7	-0.2	1.2	-0.3	-1.7
Arm fat-free mass (left)	0.3	1.5	4.0	-1.4	-0.8	-1.1	-1.5	-2.0	0.4	-1.4	-0.5	-0.8	-0.5	-1.8	1.4	1.5	-1.4	-1.4	-0.5	-1.4	-1.7	-0.1	1.3	-0.2	-1.4
Average weekly beer plus cider intake	0.3	0.5	1.0	-0.7	-0.4	-0.9	-0.8	-0.4	-0.6	-0.6	-0.7	-1.0	-0.8	-0.3	-0.8	-0.7	-0.7	-0.7	-0.9	-0.7	-0.4	-0.4	-0.6	-0.9	-0.7
Ever depressed for a whole week	0.3	0.4	1.1	0.8	0.1	0.7	0.1	0.7	0.7	0.8	0.6	0.4	0.5	0.4	0.6	0.3	0.9	0.9	0.7	0.9	0.3	1.1	0.5	0.1	0.9
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.3	0.8	1.0	0.7	1.2	1.4	0.7	1.1	0.4	1.1	1.2	0.8	0.5	0.3	0.8	0.8	1.1	0.8	1.5	0.8	1.0	0.7	0.8
Arm predicted mass (left)	0.3	1.8	4.8	-1.4	-0.8	-1.2	-1.7	-2.2	0.3	-1.6	-0.5	-0.9	-0.6	-2.0	1.4	1.4	-1.5	-1.5	-0.6	-1.5	-1.9	-0.1	1.2	-0.2	-1.5
Intelligence (Savage-Jansen 2018)	0.2	0.7	3.1	0.4	0.1	0.5	-0.2	-0.4	1.1	0.1	0.8	0.3	0.4	-0.1	1.8	1.6	0.3	0.3	0.6	0.3	-0.4	1.4	1.8	1.1	0.3
Schizophrenia (2018)	0.2	0.5	1.4	-0.7	-1.0	-0.9	-1.2	-0.3	-0.6	-0.5	-0.8	-1.1	-0.7	-0.5	-0.6	-0.7	-0.6	-0.6	-0.8	-0.6	-0.0	-0.1	-0.5	-0.9	-0.6
Lupus	0.2	0.4	2.1	0.3	-0.4	0.5	0.8	0.6	1.1	0.3	0.3	0.1	0.2	1.0	-0.3	0.3	0.2	0.2	0.3	0.2	1.0	1.4	0.9	-0.1	0.2
Primary Biliary Cirrhosis	0.2	0.3	0.7	0.6	0.3	0.4	0.5	0.8	0.5	0.8	0.0	0.3	0.3	0.1	-0.1	0.2	0.7	0.7	0.6	0.7	0.8	0.8	0.4	-0.3	0.7
Heel T-Score	0.2	1.3	4.1	0.7	0.6	0.9	1.8	1.3	1.2	0.9	0.3	1.4	1.7	2.0	0.9	0.8	0.6	0.6	1.3	0.6	1.9	0.9	1.5	0.4	0.6
Systolic Blood Pressure	0.2	1.0	2.5	-0.9	0.0	-0.7	-0.1	-1.4	-1.5	-1.2	-0.1	-1.0	-1.1	0.1	-1.3	-0.7	-0.9	-0.9	-1.2	-0.9	-1.4	-1.6	-1.4	-0.6	-0.9
Type 2 Diabetes (T2D) (2018)	0.2	0.5	1.0	0.7	0.7	0.8	0.9	0.4	0.7	0.5	1.0	0.7	0.9	0.5	0.3	0.6	0.6	0.6	0.5	0.6	0.9	0.6	0.4	0.7	0.6
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.8	0.3	0.2	0.4	0.4	0.2	0.7	0.2	0.7	0.4	0.4	0.2	0.5	0.8	0.2	0.2	0.4	0.2	0.5	0.7	0.9	0.7	0.2
Diabetes (father)	0.2	0.3	1.1	0.4	0.1	0.4	0.5	0.9	0.8	0.6	0.1	0.7	0.5	0.8	-0.0	0.4	0.4	0.4	0.6	0.4	1.1	0.3	0.5	0.1	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.2	-0.0	-0.6	-0.0	-0.2	-0.0	-0.5	-0.2	-0.3	-0.6	-0.8	0.4	-0.6	-0.7	-0.0	-0.0	-0.7	-0.0	-0.3	-0.4	-1.1	-0.7	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.3	1.0	-0.7	-0.6	-0.4	-0.4	-1.0	-0.4	-0.9	-0.3	-0.3	-0.2	-0.4	-0.6	-0.5	-0.8	-0.8	-0.5	-0.8	-0.7	-0.5	-0.1	-0.1	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.3	0.8	-0.0	0.6	-0.3	0.7	0.5	0.7	0.3	-0.3	-0.0	-0.3	0.8	-0.1	0.9	0.9	0.1	0.9	-0.1	1.1	-0.2	-0.4	0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.0	0.3	0.5	0.7	0.5	-0.2	0.7	0.1	1.0	0.6	0.9	0.6	0.9	0.6	0.3	0.3	0.5	0.3	0.0	0.6	0.9	1.0	0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.0	-0.2	-0.6	-0.2	-0.8	-0.3	-0.6	-0.3	-0.2	-0.7	-0.6	-1.0	-0.3	-0.7	-0.1	-0.1	-0.6	-0.1	-0.2	-0.0	-0.9	-0.6	-0.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	2.1	0.1	0.1	0.1	-0.4	-0.4	0.4	-0.1	0.6	-0.3	0.2	-0.1	1.4	0.9	0.1	0.1	0.1	0.1	-0.7	1.0	0.9	0.4	0.1
Medication: Ramipril	0.2	0.3	1.7	0.2	0.5	0.0	-0.8	-0.7	-0.5	-0.2	0.6	-0.3	-0.2	-0.4	0.9	0.4	0.2	0.2	-0.4	0.2	-1.3	-0.6	-0.6	0.4	0.2
Illnesses of siblings	0.2	0.3	1.0	-0.5	-0.7	-0.3	-0.2	0.3	0.7	-0.1	-0.6	0.1	0.6	0.3	0.8	0.0	-0.6	-0.6	0.3	-0.6	0.3	0.5	1.0	-0.4	-0.6
Alcohol intake versus 10 years previously	0.2	0.3	1.9	0.2	0.2	-0.0	0.4	0.4	-0.7	0.2	-0.1	-0.4	-0.7	0.3	-1.4	-1.0	0.3	0.3	-0.5	0.3	-0.0	-0.5	-1.2	-0.5	0.3
Happiness	0.2	0.2	1.3	-0.2	-0.8	-0.3	-1.1	-0.3	-0.0	-0.2	-0.8	-0.5	-0.8	-0.5	0.2	0.0	-0.2	-0.2	-0.4	-0.2	-0.6	0.0	-0.3	-0.5	-0.2
Noisy workplace	0.2	0.2	0.4	-0.5	-0.4	-0.4	-0.1	-0.6	-0.5	-0.6	-0.3	-0.4	-0.3	-0.3	-0.5	-0.2	-0.6	-0.6	-0.5	-0.6	-0.2	-0.5	-0.4	-0.3	-0.6
Mouth/teeth dental problems: Dentures	0.2	0.4	1.3	0.7	0.5	0.8	0.4	0.1	0.7	0.4	1.1	0.3	0.2	-0.0	0.5	0.5	0.7	0.7	0.2	0.7	-0.1	0.9	0.5	1.1	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	2.3	0.4	0.2	0.0	-0.6	-0.0	-0.6	0.3	0.1	-0.4	-0.5	0.7	0.5	-0.1	0.5	0.5	-0.3	0.5	-1.5	-0.6	-0.6	0.1	0.5
Length of working week for main job	0.2	0.2	0.5	-0.6	-0.1	-0.4	-0.1	-0.6	-0.4	-0.6	-0.0	-0.7	-0.5	-0.3	-0.1	-0.2	-0.6	-0.6	-0.6	-0.6	-0.3	0.1	-0.1	-0.1	-0.6
Exposure to tobacco smoke at home	0.2	0.2	0.4	0.6	0.6	0.4	0.1	0.5	0.1	0.6	0.3	0.2	0.1	0.1	0.3	0.3	0.7	0.6	0.3	0.6	0.2	0.4	-0.0	0.1	0.6
Blood clot in the leg (DVT)	0.2	0.2	0.9	0.4	0.1	0.5	0.7	0.4	0.6	0.3	0.4	0.4	0.4	0.4	-0.0	0.2	0.3	0.3	0.4	0.3	0.7	1.0	0.6	0.5	0.3
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.7	-0.7	-0.0	-0.4	0.1	-1.3	-0.6	-0.9	0.2	-0.5	-0.0	-0.0	-0.0	0.1	-0.7	-0.7	-0.5	-0.7	-0.5	-0.6	-0.1	-0.1	-0.7
Birth weight	0.2	0.4	3.6	-0.4	0.1	-0.2	-0.4	-0.9	0.2	-0.5	0.1	0.4	0.7	-0.3	1.9	1.2	-0.5	-0.5	0.3	-0.5	-0.8	-0.5	0.7	0.3	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.6	0.3	0.7	0.3	0.4	0.1	0.1	0.3	0.2	0.7	0.5	0.7	0.5	0.5	0.3	0.3	0.5	0.3	-0.4	-0.6	0.2	0.5	0.3
Qualifications: College or University degree	0.2	0.6	2.4	-0.7	-0.1	-0.3	0.1	-1.2	0.5	-0.8	0.0	0.3	0.6	0.0	1.5	1.5	-0.8	-0.8	0.3	-0.8	-0.5	-0.2	1.5	0.2	-0.8
Neck or shoulder pain in last month	0.2	0.3	1.4	0.0	0.1	-0.3	-0.6	-0.3	-0.9	-0.1	0.0	-0.6	-0.6	-0.4	0.0	-0.5	0.1	0.1	-0.6	0.1	-1.2	-0.7	-1.0	-0.3	0.1
Medication: Blood pressure	0.2	0.3	1.5	-0.3	-0.2	-0.3	-1.1	-0.9	-0.3	-0.5	-0.0	-0.6	-0.5	-0.6	0.5	0.2	-0.2	-0.2	-0.5	-0.2	-1.2	-0.5	-0.4	-0.2	-0.2
Overall health rating	0.2	0.3	0.6	-0.6	-0.6	-0.4	-0.5	-0.7	-0.4	-0.7	-0.4	-0.7	-0.5	-0.6	-0.7	-0.5	-0.6	-0.6	-0.8	-0.6	-0.2	-0.3	-0.6	-0.7	-0.6
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.0	0.3	1.0	0.2	0.1	0.4	0.0	0.4	0.3	0.3	0.6	-0.9	0.9	0.0	0.3	0.3	0.2	0.3	0.2	0.2	-0.1	0.4	0.3
Long-standing illness, disability or infirmity	0.2	0.3	1.3	0.6	0.9	0.6	0.7	-0.1	-0.0	0.3	1.2	0.3	0.4	0.8	0.4	0.6	0.6	0.6	0.1	0.6	0.3	-0.0	-0.1	0.7	0.6
Commuting to job workplace: Walk	0.2	0.2	0.8	-0.2	-0.2	-0.0	0.0	-0.7	0.2	-0.4	0.3	-0.0	0.0	0.8	0.6	0.9	-0.3	-0.3	0.0	-0.3	-0.4	-0.0	0.6	0.1	-0.3
Eye problems/disorders: Cataract	0.2	0.3	0.9	-0.6	-0.6	-0.3	-0.5	-1.0	-0.3	-0.8	-0.1	-0.6	-0.6	-0.3	0.3	0.4	-0.6	-0.6	-0.6	-0.6	-0.4	-0.2	-0.2	-0.3	-0.6
Breast cancer (self-reported)	0.2	0.2	0.5	-0.7	-0.3	-0.5	-0.3	-0.4	-0.3	-0.6	-0.4	-0.2	-0.2	-0.2	-0.4	-0.2	-0.7	-0.7	-0.4	-0.7	0.2	-0.7	-0.3	0.0	-0.7
Smoking status: Current	0.2	0.3	0.9	0.8	0.7	0.3	0.5	1.0	-0.3	0.8	0.2	0.1	-0.2	0.8	-0.2	-0.3	0.9	0.9	0.2	0.9	0.1	-0.1	-0.4	0.2	0.9
Number of self-reported non-cancer illnesses	0.2	0.3	1.7	0.2	0.2	0.4	0.3	-0.6	0.6	-0.1	0.9	0.1	0.3	0.5	0.9	1.3	0.2	0.2	0.2	0.2	0.0	0.7	0.7	0.5	0.2
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.2	-0.4	-0.4	-0.3	-0.5	-0.1	-0.1	-0.4	-0.2	-0.4	-0.1	-1.1	-0.3	-0.8	-0.4	-0.4	-0.4	-0.4	-0.1	-0.0	-0.4	-0.3	-0.4
Alcohol drinker status: Never	0.2	0.2	0.7	0.6	0.8	0.4	-0.0	0.7	0.2	0.7	0.6	0.2	0.1	0.1	0.1	-0.2	0.7	0.7	0.3	0.7	-0.3	0.4	-0.0	0.6	0.7
Number of operations (self-reported)	0.2	0.3	1.9	0.0	0.3	0.3	0.5	-0.4	0.8	-0.1	0.7	0.3	0.4	0.6	0.6	1.3	-0.0	-0.0	0.3	-0.0	0.2	0.7	1.4	0.8	-0.0
Ever had prostate specific antigen (PSA) test	0.2	0.3	1.0	-0.7	-0.9	-0.2	0.3	-0.5	0.2	-0.7	-0.1	-0.1	-0.2	-0.1	-1.0	-0.0	-0.8	-0.8	-0.3	-0.8	0.5	0.0	0.3	-0.4	-0.8
Myopia	0.2	0.4	0.9	0.5	1.0	0.5	0.6	0.2	0.5	0.4	0.8	0.6	0.6	0.9	0.3	0.8	0.5	0.5	0.6	0.5	0.0	0.3	0.8	0.8	0.5
Cholesterol lowering medication	0.2	0.3	0.9	0.4	0.1	0.6	0.7	0.1	0.7	0.3	0.8	0.4	0.2	0.5	0.5	0.9	0.4	0.4	0.4	0.4	0.5	0.9	0.7	0.6	0.4
Pain experienced in last month	0.2	0.3	0.6	0.4	0.2	0.5	0.4	0.5	0.8	0.4	0.4	0.6	0.6	-0.2	0.4	0.3	0.4	0.4	0.6	0.4	0.6	0.7	0.8	0.5	0.4
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.8	0.3	0.1	0.5	0.8	0.4	0.6	0.3	0.5	0.5	0.5	0.5	0.1	0.2	0.3	0.3	0.4	0.3	0.8	0.9	0.7	0.5	0.3
Crohns Disease (2017)	0.1	0.2	0.6	0.5	0.2	0.2	0.1	0.8	0.1	0.6	0.2	-0.2	0.0	-0.5	-0.2	-0.6	0.5	0.5	-0.0	0.5	0.5	0.8	-0.1	-0.3	0.5
Ovarian Cancer	0.1	0.1	0.8	-0.2	-0.0	-0.3	-0.7	-0.4	-0.0	-0.3	0.1	-0.3	-0.2	-0.6	0.6	0.0	-0.2	-0.2	-0.3	-0.2	-0.9	-0.1	-0.1	0.1	-0.2
Schizophrenia (2014)	0.1	0.2	0.5	-0.1	-0.7	-0.3	-0.7	0.5	-0.1	0.1	-0.5	-0.6	-0.4	-0.0	-0.5	-0.5	-0.1	-0.1	-0.4	-0.1	0.5	0.4	-0.2	-0.6	-0.1
Triglycerides	0.1	0.1	0.6	0.3	0.1	-0.0	-0.5	0.4	-0.3	0.3	-0.2	-0.0	-0.3	-0.2	-0.2	-0.6	0.3	0.3	-0.2	0.3	-0.1	-0.4	-0.8	0.1	0.3
Waist Hip Ratio (WHR)	0.1	0.3	1.2	0.7	0.3	0.5	-0.0	0.2	0.4	0.4	0.8	-0.5	-0.4	0.5	0.4	0.2	0.8	0.8	-0.2	0.8	-0.6	1.1	0.3	0.2	0.8
Allergy or Eczema	0.1	0.1	0.6	-0.3	-0.2	-0.3	-0.3	-0.5	0.1	-0.3	0.0	-0.1	0.1	0.5	0.6	0.7	-0.3	-0.3	0.1	-0.3	-0.5	-0.0	0.7	0.2	-0.3
Hair Pigment	0.1	2.4	5.8	2.0	1.8	1.6	1.4	2.4	0.6	2.2	1.0	1.5	1.3	1.1	0.3	-0.5	2.1	2.1	1.4	2.1	1.3	0.6	-0.3	1.1	2.1
Average weekly spirits intake	0.1	0.1	0.8	0.1	0.6	0.2	0.1	-0.2	0.2	0.1	0.5	0.3	0.1	-0.1	0.1	0.4	0.2	0.1	0.3	0.1	-0.6	-0.2	0.3	0.9	0.1
Relative age of first facial hair	0.1	0.3	1.3	0.2	-0.3	-0.2	-0.2	0.7	-0.6	0.4	-0.5	-0.3	-0.6	-0.2	-1.1	-1.1	0.3	0.3	-0.3	0.3	0.2	-0.4	-1.0	-0.5	0.3
Vitamin and mineral supplements	0.1	0.1	0.7	-0.0	0.2	-0.3	-0.2	0.0	-0.7	-0.0	-0.4	-0.4	-0.3	-0.1	-0.3	-0.8	0.0	0.0	-0.5	0.0	-0.2	-0.5	-0.8	-0.3	0.0
Medication: Metformin	0.1	0.2	0.7	-0.3	0.0	-0.1	-0.1	-0.6	-0.6	-0.5	0.2	-0.2	0.0	-0.4	-0.2	-0.5	-0.4	-0.4	-0.6	-0.4	-0.4	-0.8	-0.8	-0.1	-0.4
Diabetes (mother)	0.1	0.1	0.6	-0.2	-0.0	-0.2	-0.2	0.1	-0.2	-0.1	-0.4	-0.1	0.2	-0.5	0.3	-0.1	-0.2	-0.2	-0.2	-0.2	0.8	-0.2	-0.3	-0.5	-0.2
Townsend deprivation index at recruitment	0.1	0.1	0.4	-0.0	-0.2	-0.2	-0.6	-0.3	-0.1	-0.1	0.0	-0.6	-0.5	-0.5	-0.2	-0.2	0.0	0.0	-0.4	0.0	-0.6	0.4	-0.0	-0.0	0.0
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.8	-0.5	-0.6	-0.6	-0.7	-0.5	-0.2	-0.4	-0.4	-0.5	-0.3	-0.1	0.6	0.3	-0.5	-0.5	-0.2	-0.5	-0.9	-0.1	0.4	-0.2	-0.5
Multivitamins +/- minerals	0.1	0.1	0.5	-0.2	-0.6	0.0	0.2	-0.4	0.4	-0.3	0.2	0.2	-0.1	0.3	-0.6	0.6	-0.3	-0.3	0.2	-0.3	0.1	0.1	0.7	0.1	-0.3
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.3	0.2	0.4	0.3	0.2	-0.3	0.2	0.0	0.6	0.2	0.0	0.1	0.5	0.6	0.2	0.2	0.1	0.2	-0.2	0.2	0.2	0.5	0.2
Medication: Levothyroxine sodium	0.1	0.2	0.9	-0.4	-0.1	-0.3	-0.6	-0.9	-0.5	-0.6	0.0	-0.4	-0.4	-0.7	0.2	-0.1	-0.4	-0.4	-0.6	-0.4	-0.8	-0.6	-0.6	-0.2	-0.4
Chronic bronchitis/emphysema (father)	0.1	0.1	0.6	-0.3	-0.5	-0.2	-0.0	0.0	0.1	-0.1	-0.3	-0.2	-0.3	-0.6	-0.7	-0.0	-0.3	-0.3	-0.0	-0.3	0.5	0.3	0.1	-0.4	-0.3
Alcohol usually taken with meals	0.1	0.1	0.4	-0.2	-0.3	0.1	0.2	-0.2	0.4	-0.2	0.0	0.5	0.6	-0.3	0.1	0.1	-0.3	-0.3	0.3	-0.3	0.4	-0.1	0.3	-0.1	-0.3
Nervous feelings	0.1	0.2	0.7	0.1	0.2	-0.2	0.0	0.0	-0.8	0.1	-0.2	-0.1	-0.4	-0.3	-0.6	-0.6	0.1	0.1	-0.2	0.1	-0.6	-0.9	-0.8	-0.3	0.1
Qualifications: None of the above	0.1	0.2	1.4	0.4	0.0	0.2	-0.1	0.7	-0.4	0.4	0.2	-0.1	-0.4	-0.3	-0.7	-1.2	0.4	0.4	-0.3	0.4	0.2	-0.2	-1.2	0.1	0.4
Mouth/teeth dental problems	0.1	0.2	1.7	0.2	0.3	0.2	0.5	0.9	0.0	0.5	-0.2	0.6	0.7	0.5	0.1	-0.1	0.2	0.2	0.5	0.2	1.3	-0.0	-0.1	-0.1	0.2
Diabetes (self-reported)	0.1	0.1	1.0	0.2	0.4	0.4	0.1	-0.2	0.3	-0.1	1.0	-0.0	0.4	0.1	0.8	0.5	0.1	0.1	-0.1	0.1	0.2	0.5	0.2	0.3	0.1
Impedance of arm (right)	0.1	0.7	1.6	1.0	0.4	0.9	1.1	1.2	0.6	1.0	0.7	0.7	0.6	1.2	-0.2	-0.3	1.0	1.0	0.6	1.0	0.9	0.6	-0.1	0.3	1.0
Worrier / anxious feelings	0.1	0.2	0.5	-0.5	-0.1	-0.4	0.3	-0.7	-0.4	-0.6	0.1	-0.6	-0.3	-0.1	-0.0	0.5	-0.5	-0.5	-0.4	-0.5	0.0	-0.0	0.0	-0.5	-0.5
Falls in the last year	0.1	0.1	0.9	-0.3	-0.0	-0.2	0.3	-0.3	-0.2	-0.3	0.2	-0.4	-0.2	0.9	-0.1	0.2	-0.3	-0.3	-0.3	-0.3	-0.1	0.2	0.1	-0.1	-0.3
Depression (self-reported)	0.1	0.1	0.4	-0.1	-0.7	-0.0	-0.4	-0.1	0.5	-0.1	-0.1	-0.2	-0.0	0.3	0.3	0.3	-0.2	-0.2	0.0	-0.2	0.2	0.5	0.4	-0.5	-0.2
Tense / ‘highly strung’	0.1	0.2	0.5	0.3	0.3	0.4	0.3	0.3	0.6	0.4	0.4	0.3	0.3	0.2	0.3	0.5	0.3	0.3	0.4	0.3	0.3	0.7	0.6	0.2	0.3
Headache pain in last month	0.1	0.1	0.4	0.5	0.5	0.3	0.2	0.1	-0.1	0.3	0.6	0.0	-0.1	0.5	0.5	0.1	0.5	0.5	0.0	0.5	-0.6	-0.1	-0.3	0.2	0.5
Glaucoma (self-reported)	0.1	0.1	0.3	-0.2	0.0	-0.0	0.3	-0.3	0.2	-0.3	0.3	-0.1	0.0	0.1	0.3	0.6	-0.2	-0.2	-0.0	-0.2	0.1	0.3	0.4	-0.1	-0.2
Gout (self-reported)	0.1	0.1	0.8	-0.2	0.4	0.0	0.3	-0.7	-0.1	-0.4	0.3	0.3	0.1	0.4	0.4	0.9	-0.3	-0.3	-0.0	-0.3	-0.1	-0.5	0.3	0.6	-0.3
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.4	0.4	0.5	0.5	0.1	0.2	0.1	0.3	0.6	0.3	0.2	-0.1	0.3	0.0	0.4	0.4	0.2	0.4	0.1	0.1	-0.3	0.5	0.4
Number of children fathered	0.1	0.1	0.6	-0.0	0.2	0.1	0.1	-0.3	-0.0	-0.2	0.3	0.0	0.3	0.3	0.7	0.2	-0.1	-0.1	-0.0	-0.1	-0.5	-0.0	0.3	0.3	-0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.1	1.3	0.2	-0.3	0.1	-0.4	-0.2	0.0	0.0	0.0	-0.2	-0.6	0.1	0.3	0.2	0.3	0.2	-0.1	0.2	-1.1	-0.1	0.1	0.3	0.2
Migraine (self-reported)	0.1	0.1	0.2	-0.2	0.0	-0.2	0.0	-0.3	-0.5	-0.2	-0.0	-0.3	-0.2	0.1	-0.3	-0.3	-0.2	-0.2	-0.3	-0.2	-0.3	-0.3	-0.4	-0.4	-0.2
Heart disease (mother)	0.1	0.1	0.5	0.3	0.6	0.2	0.0	0.1	0.1	0.3	0.4	0.0	0.3	-0.5	0.7	0.4	0.3	0.3	0.2	0.3	0.3	0.4	0.1	0.0	0.3
Family relationship satisfaction	0.1	0.2	1.0	0.2	0.1	0.4	-0.2	-0.2	0.6	0.0	0.3	0.3	0.2	0.2	1.0	0.8	0.2	0.2	0.3	0.2	-0.3	0.4	0.5	0.4	0.2
Medication: Aspirin	0.1	0.1	0.3	-0.0	-0.4	0.0	0.2	-0.2	-0.0	-0.2	0.2	-0.4	-0.3	0.1	-0.5	-0.3	-0.0	-0.0	-0.3	-0.0	-0.5	0.5	0.1	-0.2	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	-0.3	-0.1	-0.2	-0.2	-0.4	-0.2	-0.3	-0.2	-0.2	-0.2	-0.1	0.0	0.1	-0.3	-0.3	-0.3	-0.3	-0.2	-0.5	-0.4	-0.3	-0.3
Illnesses of siblings: Diabetes	0.1	0.1	0.8	-0.2	0.2	-0.1	0.9	-0.4	-0.2	-0.3	0.4	-0.2	0.2	0.3	-0.4	0.5	-0.3	-0.3	-0.1	-0.3	0.5	0.1	0.3	-0.3	-0.3
Medication for cholesterol	0.1	0.1	0.8	-0.2	0.7	-0.2	0.4	0.2	-0.4	0.1	-0.3	0.5	0.6	0.2	-0.2	-0.2	-0.2	-0.2	0.3	-0.2	0.4	-0.9	-0.2	0.0	-0.2
Mineral and other dietary supplements	0.1	0.2	0.9	0.6	0.3	0.2	0.0	1.0	-0.0	0.7	-0.1	0.1	0.1	0.3	0.2	-0.5	0.7	0.7	0.2	0.7	0.2	0.2	-0.3	-0.0	0.7
Hearing aid user	0.1	0.1	0.3	-0.4	-0.1	-0.4	-0.4	-0.2	-0.3	-0.3	-0.3	-0.3	-0.2	-0.5	-0.1	-0.3	-0.4	-0.4	-0.4	-0.4	-0.2	-0.4	-0.3	-0.1	-0.4
Eye problems/disorders: Glaucoma	0.1	0.2	0.8	0.3	0.4	0.4	0.2	-0.2	0.5	0.1	0.7	0.3	0.3	0.4	0.7	0.9	0.2	0.2	0.3	0.2	0.0	0.4	0.5	0.5	0.2
Medication: Atorvastatin	0.1	0.1	0.4	-0.1	-0.1	-0.1	-0.1	-0.5	-0.2	-0.3	0.3	-0.4	-0.2	-0.2	0.2	0.0	-0.1	-0.1	-0.3	-0.1	-0.6	0.0	-0.1	0.1	-0.1
Irritability	0.1	0.1	0.6	-0.1	-0.1	-0.1	-0.2	-0.7	-0.3	-0.3	0.1	-0.5	-0.6	0.1	-0.0	0.5	-0.0	-0.0	-0.3	-0.0	-0.8	0.0	0.1	-0.2	-0.0
Diastolic blood pressure, automated reading	0.1	0.5	1.6	-0.4	0.1	-0.5	-0.2	-1.0	-1.0	-0.6	-0.1	-0.8	-1.1	-0.3	-0.9	-0.2	-0.3	-0.3	-0.8	-0.3	-1.3	-0.9	-0.8	-0.5	-0.3
Unable to work because of sickness or disability	0.1	0.1	0.7	-0.0	-0.4	0.2	-0.2	-0.2	0.2	-0.2	0.5	-0.5	-0.3	-0.5	-0.5	-0.2	-0.1	-0.1	-0.5	-0.1	0.6	0.8	-0.3	0.0	-0.1
Supplements: Calcium	0.1	0.1	0.3	0.1	0.2	-0.1	-0.6	0.1	-0.2	0.2	-0.2	0.2	-0.1	-0.4	0.2	0.3	0.2	0.2	0.2	0.2	-0.0	-0.5	-0.2	0.1	0.2
Basal cell carcinoma (self-reported)	0.1	0.1	0.7	-0.3	-0.4	-0.2	0.2	-0.1	-0.1	-0.3	0.1	-0.4	-0.1	-0.2	-0.9	-0.6	-0.3	-0.3	-0.4	-0.3	0.2	0.1	-0.2	-0.5	-0.3
Bipolar Disorder or Schizophrenia	0.0	0.1	0.3	-0.1	-0.2	-0.1	-0.2	-0.1	-0.1	-0.1	0.1	-0.5	-0.1	0.6	0.1	0.3	-0.0	-0.1	-0.2	-0.1	0.1	0.3	0.2	-0.2	-0.1
Bipolar Disorder (2011)	0.0	0.0	0.3	0.1	0.3	0.1	-0.1	-0.1	0.2	0.0	0.2	-0.1	-0.1	0.0	0.4	0.4	0.1	0.1	-0.0	0.1	-0.5	0.1	0.3	0.3	0.1
Crohns Disease (2012)	0.0	0.1	0.2	0.3	0.5	0.1	-0.1	0.2	-0.0	0.3	0.3	-0.2	0.0	0.1	0.5	0.2	0.4	0.4	0.0	0.4	-0.3	0.3	0.2	0.1	0.4
Rheumatoid Arthritis	0.0	0.1	0.3	-0.2	-0.3	-0.1	-0.4	-0.0	0.3	-0.1	-0.1	-0.2	-0.1	-0.3	0.3	0.1	-0.2	-0.2	-0.1	-0.2	0.2	0.6	0.2	-0.2	-0.2
Blood Eosinophil Count	0.0	0.1	0.4	-0.1	0.2	-0.1	-0.2	-0.1	-0.4	-0.1	-0.7	0.1	0.1	0.4	0.1	0.2	-0.1	-0.1	-0.2	-0.1	0.2	-0.5	-0.2	0.3	-0.1
Lung FEV1/FVC ratio	0.0	0.1	0.4	-0.3	0.0	-0.3	0.2	-0.1	-0.4	-0.2	-0.6	0.2	0.1	-0.4	-0.0	-0.2	-0.3	-0.3	0.1	-0.3	0.4	-0.6	-0.1	-0.4	-0.3
Wheeze or whistling in the chest in last year	0.0	0.0	0.3	-0.0	0.0	-0.1	-0.0	-0.2	-0.1	-0.1	0.4	-0.5	-0.3	0.0	-0.4	-0.1	-0.0	-0.0	-0.4	-0.0	-0.2	0.4	-0.0	0.2	-0.0
Shortness of breath walking on level ground	0.0	0.0	0.2	0.1	-0.1	0.2	-0.2	-0.1	0.0	-0.1	0.4	-0.3	-0.3	0.1	-0.0	-0.0	0.1	0.1	-0.4	0.1	0.0	0.3	-0.4	0.1	0.1
Medication: Aspirin	0.0	0.1	0.3	-0.0	-0.3	0.1	0.3	-0.3	0.1	-0.2	0.3	-0.3	-0.1	0.0	-0.4	-0.1	-0.1	-0.1	-0.2	-0.1	-0.4	0.6	0.3	-0.0	-0.1
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.2	-0.0	0.1	-0.2	-0.2	0.1	-0.4	0.0	-0.2	-0.2	-0.1	-0.3	0.1	-0.2	0.0	0.0	-0.2	0.0	-0.2	-0.5	-0.4	-0.2	0.0
Medication: Omeprazole (e.g. Zanprol)	0.0	0.1	0.2	0.3	0.0	0.1	-0.2	0.3	0.0	0.2	0.2	-0.2	-0.0	0.1	0.4	-0.0	0.3	0.3	-0.1	0.3	-0.0	0.3	-0.3	-0.4	0.3

Hub : Genes

LOC375190

Models

Trait associations