TWAS hub - LOC440957

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Brain Lower Grade Glioma	0.0302	0.0179	0.0075	0.003	0.013	0.004	NA	0.003	0.1400	0.0098	0.100	NA	0.1500
2	TCGA	Ovarian Serous Cystadenocarcinoma	0.0400	0.0270	0.0068	0.017	0.008	0.000	NA	0.002	0.0240	0.0880	0.300	NA	0.2400
3	TCGA	Prostate Adenocarcinoma	0.0512	0.0320	0.0018	0.017	0.016	0.013	NA	0.019	0.0063	0.0078	0.014	NA	0.0043

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Waist Hip Ratio (WHR)	25.2	113.5	156.2	-12.5	-12.0	6.3
Age when periods started (menarche)	13.2	31.6	37.3	6.1	6.1	-4.6
Worry (Nagel 2018)	11.0	23.1	38.5	-4.5	-6.2	3.3
Wears glasses or contact lenses	9.7	11.2	13.5	3.4	3.7	-2.8
Verbal and Numeric Reasoning (VNR)	8.9	21.5	34.0	4.3	5.8	-3.5
Bipolar Disorder or Schizophrenia	8.5	20.8	33.5	-3.8	-5.8	3.8
HDL Cholesterol	8.3	13.9	27.1	5.2	3.6	-1.3
Impedance of whole body	8.2	41.7	70.6	-6.8	-8.4	3.0
Headache pain in last month	7.8	13.5	19.4	-2.6	-4.4	3.8
Intelligence (Savage-Jansen 2018)	7.6	23.4	38.3	3.9	6.2	-4.1
Impedance of leg (left)	7.6	37.1	59.0	-7.0	-7.7	1.6
Bipolar Disorder (2018)	7.4	11.7	16.5	-2.8	-4.1	3.3
Pulse rate	7.1	11.9	16.4	-3.6	-4.1	2.5
Schizophrenia (2014)	7.0	15.4	25.9	-3.7	-5.1	2.6
Impedance of leg (right)	6.9	33.3	52.7	-6.8	-7.3	1.0
Triglycerides	6.7	11.0	17.0	-4.1	-3.0	2.6
Worrier / anxious feelings	6.5	12.3	21.2	-3.9	-4.6	0.9
Nervous feelings	6.4	12.0	18.4	-2.7	-4.3	3.2
Impedance of arm (left)	6.3	29.0	51.0	-5.2	-7.1	3.0
Blood Red Count	6.0	58.2	91.2	-7.8	-9.6	4.7
Impedance of arm (right)	6.0	27.9	49.0	-5.2	-7.0	2.7
Average weekly champagne plus white wine intake	5.9	8.0	10.1	2.7	3.2	-2.6
Pulse rate, automated reading	5.8	18.9	32.9	-5.7	-4.8	1.1
Illness, injury, bereavement, stress in last 2 years	5.4	6.6	9.9	3.1	3.0	-0.9
Mouth/teeth dental problems: Bleeding gums	5.3	6.9	11.5	-3.0	-3.4	0.7
Medication: Paracetamol	5.3	8.8	10.4	-3.0	-3.2	2.6
Glaucoma (self-reported)	5.3	6.2	10.6	-3.2	-2.9	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	5.3	6.9	9.4	-2.5	-3.1	2.2
Stomach or abdominal pain in last month	4.8	6.0	8.9	-2.6	-3.0	1.6
Schizophrenia (2018)	4.7	9.8	17.3	-2.7	-4.2	2.2
Type 2 Diabetes (T2D) (2012)	4.7	5.5	7.3	-2.7	-2.4	1.8
BMI	4.7	27.2	43.4	5.6	6.6	-2.6
Bilateral oophorectomy (both ovaries removed)	4.7	5.4	9.6	-3.1	-2.4	1.0
Medication: Blood pressure	4.7	8.3	9.9	2.6	3.1	-2.9
Neuroticism	4.6	11.1	17.5	-1.8	-4.2	3.5
Pack years adult smoking proportion	4.6	7.1	9.0	-3.0	-3.0	1.8
Commuting to job workplace: Cycle	4.4	5.3	7.3	1.8	2.3	-2.7
Age at First Birth	4.3	6.3	9.9	2.6	3.1	-1.4
Frequency of tiredness / lethargy in last 2 weeks	4.3	7.0	8.7	-2.7	-3.0	2.2
Prospective memory result	4.3	5.3	8.6	-1.4	-2.9	2.3
Ever used hormone-replacement therapy (HRT)	4.2	5.4	10.7	-3.3	-2.1	1.0
Basal cell carcinoma (self-reported)	4.2	5.0	8.0	-2.4	-2.8	1.0
Frequency of tenseness / restlessness in last 2 weeks	4.1	6.3	9.1	-1.8	-3.0	2.6
Fluid intelligence score	4.1	8.4	14.5	2.5	3.8	-2.1
Ever smoked	4.1	7.2	10.9	2.3	3.3	-2.4
Medication for cholesterol, blood pressure or diabetes	4.0	6.6	8.2	-2.2	-2.9	2.6
Serious illness, injury or assault to yourself	3.8	4.6	7.6	-2.8	-2.3	0.8
Suffer from ‘nerves’	3.8	6.0	10.4	-0.7	-2.6	3.2
Neuroticism (Nagel 2018)	3.7	8.7	14.8	-1.9	-3.8	2.8
Average weekly spirits intake	3.6	4.5	7.1	2.7	2.5	-0.4
Major Depression (MDD)	3.5	4.2	6.5	-1.4	-2.5	2.0
Rheumatoid Arthritis	3.5	4.8	6.2	1.8	2.5	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	3.5	5.3	6.8	-1.6	-2.6	2.6
Relative age voice broke	3.4	5.1	8.1	1.2	2.4	-2.8
Medication for hormone replacement therapy	3.2	3.6	8.2	-2.9	-1.6	0.3
Heart attack	3.2	4.0	9.8	0.3	1.5	-3.1
Comparative height size at age 10	3.2	17.9	39.2	-0.9	-3.7	6.3
Guilty feelings	3.2	4.8	7.5	-1.3	-2.7	2.2
Medication: Cholesterol lowering	3.1	4.9	7.8	1.4	2.2	-2.8
Wheeze or whistling in the chest in last year	3.1	5.6	7.7	-1.5	-2.6	2.8
Pack years of smoking	3.1	4.6	6.2	-2.3	-2.5	1.4
Pulse wave reflection index	3.0	3.7	5.8	2.1	2.4	-1.0
Frequency of depressed mood in last 2 weeks	2.9	4.0	7.3	-1.2	-1.8	2.7
Depression (Nagel 2018)	2.8	4.2	5.1	-1.6	-2.2	2.3
Forced expiratory volume in 1-second (FEV1), predicted	2.8	5.7	14.3	0.5	-1.6	3.8
Ulcerative Colitis	2.7	3.9	5.9	-1.3	-2.4	2.0
Medication: Levothyroxine sodium	2.7	4.5	6.6	2.0	1.7	-2.6
Worry too long after embarrassment	2.7	4.6	5.1	-2.2	-1.9	2.2
Sitting height	2.6	18.4	47.7	1.9	-2.0	6.9
Gout (self-reported)	2.6	3.6	4.8	-1.9	-2.2	1.5
Medication: Atorvastatin	2.6	3.2	8.5	-0.1	1.1	-2.9
Myopia	2.6	3.8	7.0	1.3	2.6	-1.7
Ever had hysterectomy (womb removed)	2.5	2.8	6.1	-2.5	-1.3	0.7
High blood pressure (mother)	2.5	3.5	5.5	-2.3	-2.1	0.8
Heart attack/myocardial infarction (self-reported)	2.5	3.3	8.7	-0.1	1.1	-2.9
Lung FEV1/FVC ratio	2.4	12.3	16.3	2.3	3.9	-4.0
Allergy	2.4	5.5	8.1	1.5	2.4	-2.8
Alcohol intake versus 10 years previously	2.4	3.6	5.0	1.7	2.2	-1.7
Trunk predicted mass	2.4	13.5	24.9	5.0	3.6	1.7
Medication for pain relief, constipation, heartburn	2.4	4.0	4.9	2.2	2.2	-1.6
Medication for cholesterol	2.4	3.6	9.2	3.0	0.6	1.1
Leg fat-free mass (left)	2.3	12.1	21.5	4.6	3.3	2.1
Leg predicted mass (left)	2.3	12.2	21.8	4.7	3.3	2.0
Neuroticism score	2.3	4.8	6.7	-1.1	-2.6	2.6
Trunk fat-free mass	2.3	13.0	23.8	4.9	3.5	1.8
Whole body fat-free mass	2.3	12.9	23.1	4.8	3.4	2.1
Whole body water mass	2.3	13.4	23.8	4.9	3.5	2.0
Chest pain or discomfort	2.2	3.2	5.2	-1.3	-2.3	1.6
Family relationship satisfaction	2.2	2.7	3.8	-1.0	-1.9	1.8
Leg fat-free mass (right)	2.2	11.9	20.6	4.5	3.1	2.4
Leg predicted mass (right)	2.2	11.6	19.8	4.5	3.1	2.3
Illnesses of father: High blood pressure	2.2	2.7	3.4	1.4	1.6	-1.8
Height	2.1	39.9	84.3	1.2	-5.8	9.2
Hip circumference	2.1	8.8	14.2	3.8	3.5	-0.1
Breastfed as a baby	2.1	2.7	4.8	2.2	1.7	-0.4
Ever highly irritable/argumentative for 2 days	2.1	2.5	5.1	0.9	2.3	-1.3
Arm fat-free mass (right)	2.1	10.9	19.4	4.4	3.1	1.8
Arm predicted mass (right)	2.1	11.0	20.0	4.5	3.3	1.5
Tinnitus: Yes, now most or all of the time	2.1	2.5	4.3	-1.3	-2.1	1.2
Pain type(s) experienced in last month: Hip pain	2.1	2.6	5.9	-2.4	-1.4	0.3
Medication: Paracetamol	2.1	3.2	3.3	-1.7	-1.8	1.8
Multivitamins +/- minerals	2.0	2.5	4.4	1.6	2.1	-0.7
Hearing difficulty/problems with background noise	2.0	3.2	4.0	-1.5	-1.8	2.0
Standing height	2.0	19.5	45.0	1.0	-3.5	6.7
Arm fat-free mass (left)	2.0	10.0	17.8	4.2	3.0	1.7
Neuroticism (2016)	1.9	2.7	4.0	-0.6	-2.0	1.9
Blood Platelet Count	1.9	21.7	41.7	1.5	4.6	-6.5
Vitamin and mineral supplements	1.9	2.5	3.4	-1.8	-1.8	0.9
Body mass index (BMI)	1.9	8.1	15.1	2.7	3.9	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.9	4.0	11.2	-0.6	0.6	-3.4
Basal metabolic rate	1.9	10.6	18.6	4.3	3.0	2.1
Diastolic blood pressure, automated reading	1.9	5.8	8.1	-2.8	-2.4	1.9
Arm predicted mass (left)	1.9	9.8	17.0	4.1	3.1	1.6
Systolic blood pressure, automated reading	1.8	5.2	9.4	1.6	3.1	-1.9
Medication: Co-codamol	1.8	2.1	4.3	-2.1	-1.0	-1.1
Medication: Atenolol	1.8	2.3	6.2	-0.5	0.6	-2.5
Hair/balding pattern: Pattern 2	1.8	2.3	3.1	1.8	1.2	-1.5
Eye problems/disorders: Glaucoma	1.8	2.1	3.5	-1.9	-1.7	-0.3
Ulcerative Colitis (UC)	1.7	3.1	5.3	-1.0	-1.7	2.3
Severe depression (siblings)	1.7	1.9	3.2	-1.8	-1.5	0.3
Past tobacco smoking	1.7	3.1	5.2	-1.2	-2.3	1.6
Falls in the last year	1.7	2.2	4.0	-2.0	-1.1	1.2
Illnesses of mother	1.7	2.1	3.3	1.3	1.8	-1.1
Tense / ‘highly strung’	1.7	2.9	5.6	-1.2	-2.4	1.3
Overall health rating	1.7	3.6	6.9	-2.6	-1.9	0.4
Hypertension (Self-reported)	1.7	4.6	7.2	1.2	2.3	-2.7
Primary Biliary Cirrhosis	1.6	2.3	3.4	0.9	1.8	-1.7
Heel T-Score	1.6	12.9	36.0	-0.4	1.6	-6.0
Hayfever, allergic rhinitis or eczema	1.6	3.5	4.5	-1.6	-1.9	2.1
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.7	7.8	-1.8	-0.2	-2.8
Length of working week for main job	1.6	1.7	3.2	1.8	1.4	-0.3
Neck or shoulder pain in last month	1.6	2.2	3.6	-1.9	-1.7	0.5
Medication: Allopurinol	1.6	2.2	3.1	-1.7	-1.8	0.8
Schizophrenia vs Biploar Disorder	1.5	2.0	5.2	0.6	0.6	-2.3
Ovarian Cancer	1.5	2.0	4.0	-2.0	-1.4	0.1
Fasting Glucose	1.5	1.8	2.6	-1.4	-0.9	1.6
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.4	8.2	-1.4	0.2	-2.9
Diverticular disease/diverticulitis (self-reported)	1.5	1.8	4.3	-2.1	-1.0	-0.2
Number of incorrect matches in round	1.5	2.5	5.0	-0.5	-2.2	1.5
Pain all over the body in last month	1.5	1.7	2.5	-1.2	-1.6	1.0
Hypothyroidism/myxoedema (self-reported)	1.5	3.0	4.7	1.7	1.2	-2.2
Alcohol intake frequency.	1.5	3.5	4.0	-1.9	-2.0	1.7
Commuting to job workplace: Walk	1.5	1.6	3.4	-1.8	-1.2	0.1
Illnesses of father: None of the above (group 1)	1.5	1.8	4.0	-0.7	-1.0	2.0
Risk taking	1.5	2.2	3.3	-1.8	-1.7	0.6
Breast Cancer	1.4	3.3	5.5	1.7	2.4	-1.2
Hypothyroidism (self reported)	1.4	3.2	6.0	1.6	1.1	-2.4
Maternal smoking around birth	1.4	2.0	3.3	-1.8	-1.6	0.5
Taking other prescription medications	1.4	2.2	4.2	-1.5	-0.6	-2.0
Qualifications: CSEs or equivalent	1.4	1.9	4.9	0.2	-0.9	2.2
High blood pressure	1.4	4.0	5.7	1.2	2.2	-2.4
Qualifications: A levels/AS levels or equivalent	1.4	3.2	4.8	1.9	2.2	-1.1
Birth weight	1.4	3.0	6.8	1.5	0.1	2.6
Shortness of breath walking on level ground	1.4	1.6	4.1	-0.4	-0.8	2.0
Illnesses of father: Heart disease	1.4	2.0	4.9	-1.0	0.2	-2.2
Diabetes diagnosed by doctor	1.4	2.2	3.7	0.2	1.7	-1.9
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	4.3	-2.1	-0.9	-0.4
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	3.1	-1.0	-1.8	1.1
Systolic Blood Pressure	1.3	6.6	10.7	0.8	3.3	-2.9
Number of full brothers	1.3	1.6	2.6	1.2	1.6	-0.8
Medication: Ibuprofen	1.3	1.6	2.5	1.4	1.6	-0.4
Medication: Omeprazole	1.3	1.6	4.0	-2.0	-0.8	-0.2
Friendships satisfaction	1.3	1.7	3.7	0.7	-0.9	1.9
Irritability	1.3	2.2	4.5	2.1	1.4	0.2
Vascular/heart problems diagnosed by doctor	1.3	3.4	6.1	-0.9	-1.9	2.5
Alzheimer’s Disease (in father)	1.2	1.2	2.7	1.6	0.9	-0.4
Tanning	1.2	15.1	21.5	3.7	4.6	-3.2
Weight	1.2	5.7	9.7	3.1	2.2	1.6
Depression (self-reported)	1.2	1.4	2.4	-1.4	-1.6	-0.3
Medication: Lansoprazole	1.2	1.3	2.7	-1.6	-1.1	-0.5
Migraine (self-reported)	1.2	1.5	2.6	0.0	-1.6	1.4
Illnesses of siblings: Diabetes	1.2	1.4	2.0	1.0	1.4	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.5	2.4	-0.2	-1.6	1.4
Osteoarthritis (self-reported)	1.2	1.6	2.6	-1.6	-1.4	-0.5
Body Mass Index (BMI) (2010)	1.1	1.5	2.2	1.3	1.5	-0.7
LDL Cholesterol	1.1	1.8	2.7	-1.3	0.9	-1.7
Smoking Status	1.1	2.6	5.2	0.4	2.3	-1.6
Medication: Ramipril	1.1	1.4	2.7	0.6	1.1	-1.6
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	1.7	-1.3	-1.3	0.7
Age at first live birth	1.1	1.9	2.5	1.6	1.6	-0.9
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.4	2.0	-1.4	-1.2	-0.8
Mood swings	1.1	2.1	5.0	0.5	-1.0	2.2
Ever had prostate specific antigen (PSA) test	1.1	1.3	2.1	1.4	1.0	-0.9
Blood White Count	1.0	7.4	18.5	-4.3	-1.9	0.1
Medication: Metformin	1.0	1.4	1.8	1.1	1.4	-1.1
Waist circumference	1.0	3.5	4.0	-2.0	-1.7	1.9
Mouth/teeth dental problems	1.0	1.5	1.8	1.0	1.3	-1.4
Diabetes (self-reported)	1.0	1.6	2.3	0.3	1.5	-1.5
Blood clot in the leg (DVT)	1.0	1.3	2.5	-1.0	-1.6	0.5
Eye problems/disorders: None of the above	1.0	1.1	2.3	0.8	1.5	-0.6
Had major operations	1.0	1.1	3.2	-0.1	0.3	-1.8
Knee pain experienced in last month	1.0	1.6	3.0	-1.7	-0.9	-1.0
Long-standing illness, disability or infirmity	1.0	1.5	4.1	-2.0	-0.5	0.2
Age started oral contraceptive pill	1.0	1.3	1.7	1.2	0.7	-1.3
Alzheimer’s Disease (in mother)	0.9	1.1	2.9	0.2	-0.4	1.7
Financial difficulties in last 2 years	0.9	1.2	2.6	-1.6	-1.0	-0.0
Happiness	0.9	1.1	1.4	0.9	-1.0	1.2
Medication: Ventolin 100micrograms inhaler	0.9	1.2	2.1	-1.4	-1.0	0.6
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	4.4	0.3	0.0	2.1
Back pain experienced in last month	0.9	1.3	2.7	0.6	1.6	-0.9
Miserableness	0.9	1.5	2.7	1.6	1.1	0.8
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.4	0.8	1.5	-0.8
High cholesterol (Self-reported)	0.9	1.5	2.4	0.9	1.5	-1.2
Medication: Bendroflumethiazide	0.9	1.3	3.1	0.5	1.8	-0.8
Alcohol drinker status: Never	0.9	1.1	1.5	-1.2	-1.2	-0.6
Alcohol drinker status: Previous	0.9	1.0	2.2	-1.5	-0.9	0.1
Cardiovascular Disease	0.8	2.6	4.0	0.5	1.9	-2.0
Respiratory disease	0.8	1.7	4.5	0.0	-0.7	2.1
Number of treatments/medications taken	0.8	1.4	2.8	-0.8	0.9	-1.7
Sensitivity / hurt feelings	0.8	1.3	2.2	-1.3	-1.5	0.4
Hand grip strength (right)	0.8	2.1	6.1	2.5	0.6	0.2
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	1.5	-0.6	-0.9	1.2
Forced vital capacity (FVC)	0.8	3.0	6.9	-0.1	-1.5	2.6
Number of live births	0.8	1.2	3.0	-0.7	0.1	-1.7
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	1.1	-1.1	-0.7	1.0
Breast cancer (self-reported)	0.8	0.9	1.8	-1.3	-0.9	0.4
Depressed Affect (Nagel 2018)	0.7	1.5	3.3	0.6	-0.9	1.8
Alzheimer’s Disease (including proxy)	0.7	1.0	1.9	1.4	0.3	1.0
Irritable Bowel Disease (IBD)	0.7	1.6	2.3	-0.7	-1.5	1.5
Type 2 Diabetes (T2D) (2018)	0.7	1.2	2.5	0.0	1.1	-1.6
Angina	0.7	1.0	1.3	1.0	1.2	-0.8
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	1.6	-1.0	-1.3	0.5
Medication: Amlodipine	0.7	1.0	1.6	0.0	1.2	-1.1
Forced vital capacity (FVC), Best measure	0.7	2.6	6.0	-0.1	-1.3	2.4
Comparative body size at age 10	0.7	2.0	5.0	0.7	2.2	-0.8
Number of full sisters	0.7	0.9	2.2	0.5	0.4	1.5
Loneliness, isolation	0.7	0.9	1.5	1.1	-0.2	1.2
Hearing aid user	0.7	0.8	2.0	0.5	1.4	-0.2
Ever depressed for a whole week	0.7	0.9	1.7	-1.3	-0.8	0.6
Diabetes (mother)	0.6	0.8	1.4	-1.2	-1.0	-0.3
Average weekly fortified wine intake	0.6	0.7	1.9	1.4	0.4	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.9	2.3	-0.3	-0.5	1.5
Had other major operations	0.6	0.8	1.6	-1.2	-0.8	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.1	1.1	0.8	0.7
Angina (self-reported)	0.6	0.8	1.0	0.7	1.0	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.4	0.1	1.2	-0.8
Arm fat mass (left)	0.6	2.5	3.8	2.0	1.8	0.5
Blood Eosinophil Count	0.5	3.5	9.2	0.6	3.0	-1.0
Lung FVC	0.5	2.6	5.4	-0.7	1.4	-2.3
Hand grip strength (left)	0.5	1.4	2.7	1.0	-0.8	1.6
Alcohol usually taken with meals	0.5	0.7	1.5	-0.8	-1.2	-0.1
Had menopause	0.5	0.6	1.4	0.1	0.5	-1.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.4	-1.2	-0.5	0.1
Arm fat mass (right)	0.5	2.2	3.3	1.8	1.8	0.5
Age at last live birth	0.5	0.8	1.0	1.0	0.9	-0.7
Smoking status: Previous	0.5	0.7	1.3	0.6	1.1	-0.7
Medication: Gliclazide	0.5	0.5	1.0	-1.0	-0.5	-0.6
Pain experienced in last month	0.5	0.8	1.3	0.9	0.6	-1.1
Prostate Cancer	0.4	0.5	1.5	-0.2	-1.2	0.1
Allergy or Eczema	0.4	1.0	1.5	-0.7	-1.0	1.2
Hearing difficulty/problems: Yes	0.4	0.5	1.5	-1.2	-0.3	-0.0
Trunk fat percentage	0.4	1.4	2.1	-0.8	-1.4	1.3
Townsend deprivation index at recruitment	0.4	0.5	1.0	0.7	1.0	0.2
Fed-up feelings	0.4	0.6	1.1	-0.3	-0.9	1.0
Father’s age at death	0.4	0.6	1.7	0.3	-0.1	1.3
Noisy workplace	0.4	0.5	0.7	0.5	0.8	-0.8
Peak expiratory flow (PEF)	0.4	1.0	1.7	1.3	0.5	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	0.7	0.3	-0.7	0.9
Leg fat mass (right)	0.4	1.4	2.4	1.4	1.6	0.1
Qualifications: nursing, teaching	0.4	0.7	1.5	0.1	0.7	-1.2
Mineral and other dietary supplements	0.4	0.6	1.5	-0.5	-1.2	-0.1
Asthma (self-reported)	0.4	0.8	1.5	-0.5	-0.7	1.2
Medication: Aspirin	0.4	0.5	0.6	-0.8	-0.7	-0.6
Medication: Blood pressure	0.4	0.9	1.4	-0.7	0.8	-1.2
Number of operations (self-reported)	0.4	0.7	1.3	-1.1	-0.9	0.0
Fractured/broken bones in last 5 years	0.4	0.5	1.1	0.6	1.1	0.4
Unable to work because of sickness or disability	0.4	0.5	1.2	-1.1	-0.5	0.3
Leg fat mass (left)	0.4	1.4	2.1	1.4	1.4	0.3
Chronotype (morning person)	0.3	0.8	1.7	-1.3	-0.1	0.7
Relative age of first facial hair	0.3	0.6	1.0	0.6	0.7	-1.0
Trunk fat mass	0.3	1.2	3.0	0.8	-0.2	1.7
Qualifications: None of the above	0.3	0.6	1.1	1.1	0.6	0.6
Medication: Simvastatin	0.3	0.4	0.5	0.7	0.7	-0.4
Asthma	0.3	0.5	1.0	-0.5	-0.6	1.0
Exposure to tobacco smoke at home	0.3	0.3	0.7	0.9	0.1	0.4
Hair/balding pattern: Pattern 4	0.3	0.8	1.2	0.5	1.1	-1.0
Loud music exposure frequency	0.3	0.3	0.4	-0.6	-0.5	-0.5
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.8	-0.3	-0.9	0.2
Exposure to tobacco smoke outside home	0.3	0.4	1.0	-0.4	-1.0	0.5
Pulse wave peak to peak time	0.3	0.3	0.4	0.5	-0.7	0.6
Qualifications: College or University degree	0.3	0.9	1.6	-0.9	-1.3	0.4
Medication: Seretide 50 evohaler	0.3	0.3	0.6	0.3	0.6	0.8
Heart disease (mother)	0.3	0.4	1.0	-0.5	-0.1	-1.0
Eye problems/disorders: Cataract	0.3	0.4	1.1	-0.1	-1.1	-0.1
Smoking status: Current	0.3	0.4	1.0	-0.0	1.0	-0.6
Number of self-reported non-cancer illnesses	0.3	0.5	1.2	-0.5	0.1	-1.1
Commuting to job workplace: Public transport	0.3	0.4	0.7	-0.8	-0.7	-0.1
Medication: Lisinopril	0.3	0.4	0.8	-0.5	0.4	-0.9
Coronary Artery Disease (CAD)	0.2	0.2	0.4	-0.6	-0.1	-0.6
HbA1C	0.2	0.2	0.5	0.2	0.0	-0.7
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.4	-0.7	-0.5	-0.0
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.3	-0.1	0.6	-0.5
Diabetes (father)	0.2	0.3	0.5	-0.7	-0.5	0.3
Arm fat percentage (right)	0.2	0.7	1.3	0.9	1.2	-0.1
Time employed in main current job	0.2	0.2	0.4	-0.3	0.6	-0.4
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.6	0.5	-0.3	1.3
Birth weight of first child	0.2	0.3	0.6	0.3	-0.5	0.7
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	0.6	0.7	-0.1	0.8
Leg fat percentage (right)	0.2	0.8	1.8	-0.3	0.7	-1.4
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.5	-0.4	-0.7	0.3
Whole body fat mass	0.2	0.7	1.1	1.1	0.6	0.9
Leg pain on walking	0.2	0.2	0.4	-0.7	-0.2	-0.5
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.5	0.7	0.1	0.3
Medication: Aspirin	0.2	0.3	0.4	-0.6	-0.5	-0.6
Supplements: Vitamin C	0.2	0.2	0.4	-0.6	-0.2	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.4	0.4	0.6	0.5
Average weekly red wine intake	0.2	0.3	0.6	0.8	0.4	0.5
Ever had bowel cancer screening	0.2	0.3	0.7	-0.3	0.2	-0.8
Osteoporosis (self-reported)	0.2	0.3	0.6	-0.5	0.1	-0.8
Mother’s age at death	0.2	0.3	0.7	0.9	-0.2	0.1
Heart disease (siblings)	0.2	0.2	0.3	-0.5	-0.5	-0.3
Reaction Time	0.1	0.1	0.4	-0.1	-0.6	0.1
Crohns Disease (2012)	0.1	0.2	0.5	-0.2	-0.7	-0.3
Mean Putamen Volume	0.1	0.1	0.2	-0.1	-0.5	0.3
Lupus	0.1	0.2	0.5	0.2	0.1	-0.7
Supplements: Zinc	0.1	0.1	0.2	-0.5	-0.1	0.4
Current tobacco smoking	0.1	0.1	0.2	-0.3	0.5	-0.1
Supplements: Glucosamine	0.1	0.1	0.2	-0.4	0.1	-0.3
Illnesses of siblings	0.1	0.1	0.3	-0.2	-0.3	0.5
Hair/balding pattern: Pattern 3	0.1	0.2	0.3	-0.1	0.6	-0.5
Mouth/teeth dental problems: Dentures	0.1	0.1	0.2	0.3	0.5	0.4
Lung cancer (father)	0.1	0.2	0.2	-0.4	-0.5	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.9	0.1	-0.4	1.0
Pulse wave Arterial Stiffness index	0.1	0.1	0.2	-0.4	0.4	-0.0
Body fat percentage	0.1	0.3	0.3	-0.4	-0.6	0.5
Number of children fathered	0.1	0.1	0.2	-0.1	0.3	0.4
Health satisfaction	0.1	0.2	0.4	-0.7	-0.0	-0.3
Mean time to correctly identify matches	0.1	0.2	0.4	0.3	-0.1	-0.6
Arm fat percentage (left)	0.1	0.6	1.0	0.9	1.0	0.0
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.1	0.3	0.3	0.2
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.1	0.3	0.4
Financial situation satisfaction	0.1	0.1	0.2	-0.4	-0.3	0.3
Leg fat percentage (left)	0.1	0.5	1.1	-0.2	0.7	-1.1
Average weekly beer plus cider intake	0.1	0.2	0.4	0.3	-0.3	0.6
Cholesterol lowering medication	0.1	0.2	0.5	-0.7	-0.1	-0.2
Supplements: Calcium	0.1	0.1	0.3	-0.1	-0.2	0.5
Crohns Disease (2017)	0.0	0.1	0.1	0.3	-0.3	-0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.5	1.1	0.6	0.2	1.0
Chronic bronchitis/emphysema (father)	0.0	0.0	0.1	0.2	-0.0	-0.3
High blood pressure (siblings)	0.0	0.0	0.0	-0.2	0.2	-0.1
Emphysema/chronic bronchitis	0.0	0.1	0.1	0.3	-0.0	-0.3

Hub : Genes

LOC440957

Models

Trait associations