TWAS hub - LOC645752

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.108	0.0331	0.0e+00	0.142	0.105	0.145	NA	0.114	7.5e-28	1.0e-20	1.7e-28	NA	1.7e-22
2	TCGA	Glioblastoma Multiforme	0.204	0.0940	1.8e-04	0.178	0.095	0.130	NA	0.147	4.3e-06	8.0e-04	9.1e-05	NA	3.3e-05
3	TCGA	Kidney Renal Clear Cell Carcinoma	0.245	0.0616	0.0e+00	0.233	0.240	0.271	NA	0.254	6.3e-26	1.1e-26	1.6e-30	NA	2.0e-28
4	TCGA	Kidney Renal Papillary Cell Carcinoma	0.367	0.0850	0.0e+00	0.343	0.274	0.335	NA	0.199	2.0e-20	5.9e-16	7.5e-20	NA	1.3e-11
5	TCGA	Brain Lower Grade Glioma	0.259	0.0691	0.0e+00	0.335	0.296	0.321	NA	0.334	4.0e-39	5.3e-34	2.8e-37	NA	5.2e-39
6	TCGA	Lung Adenocarcinoma	0.176	0.0511	0.0e+00	0.153	0.141	0.184	NA	0.090	1.7e-17	3.6e-16	5.5e-21	NA	1.1e-10
7	TCGA	Lung Squamous Cell Carcinoma	0.122	0.0411	6.7e-13	0.090	0.100	0.117	NA	0.079	2.0e-10	1.8e-11	3.4e-13	NA	2.9e-09
8	TCGA	Ovarian Serous Cystadenocarcinoma	0.174	0.0850	1.8e-04	0.053	0.045	0.048	NA	0.047	1.8e-04	5.4e-04	3.6e-04	NA	3.8e-04
9	TCGA	Pancreatic Adenocarcinoma	0.413	0.0940	2.3e-10	0.162	0.231	0.210	NA	0.172	2.7e-07	4.5e-10	3.1e-09	NA	1.1e-07
10	TCGA	Pheochromocytoma and Paraganglioma	0.140	0.0760	6.0e-04	0.049	0.067	0.035	NA	0.068	5.2e-03	1.2e-03	1.5e-02	NA	1.1e-03
11	TCGA	Soft Tissue Sarcoma	0.164	0.0610	3.4e-09	0.180	0.087	0.152	NA	0.060	6.8e-11	7.8e-06	2.4e-09	NA	2.0e-04
12	TCGA	Testicular Germ Cell Tumors	0.176	0.0700	3.7e-06	0.112	0.120	0.124	NA	0.080	9.1e-05	5.3e-05	4.0e-05	NA	8.8e-04
13	TCGA	Thyroid Carcinoma	0.339	0.0790	0.0e+00	0.387	0.346	0.386	NA	0.385	8.0e-40	7.6e-35	1.2e-39	NA	1.5e-39

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Illnesses of father: None of the above (group 1)	6.8	8.4	10.0	-2.6	-3.1	-2.8	-2.8	-3.1	-3.0	-2.8	-2.6	-2.8	-3.1	-3.0	-2.5	-3.2
Chronotype (morning person)	6.2	14.4	19.7	3.9	4.0	3.9	4.0	3.9	4.3	3.3	3.1	2.8	3.5	4.1	4.4	3.8
Mouth/teeth dental problems: Dentures	5.7	9.7	13.0	3.1	2.8	3.2	3.1	2.8	3.2	3.5	3.6	3.3	3.0	2.9	2.6	3.3
Medication: Metformin	5.4	7.7	13.0	3.2	2.4	2.7	3.6	2.4	3.5	2.5	2.5	2.8	2.2	2.8	2.5	2.5
Medication: Atorvastatin	4.6	5.6	8.1	2.5	2.3	1.9	2.8	2.3	2.7	2.2	2.3	2.9	2.0	2.4	2.0	2.2
Medication: Atenolol	4.3	5.3	9.2	2.4	2.4	2.2	2.1	2.5	2.0	2.5	1.2	3.0	2.5	2.4	1.5	2.6
Breastfed as a baby	4.1	5.0	6.8	-2.4	-2.3	-2.1	-2.6	-2.4	-2.3	-2.4	-0.7	-1.9	-2.3	-2.3	-2.6	-2.3
Eye problems/disorders: None of the above	4.1	4.8	6.5	-2.2	-2.2	-2.1	-2.5	-2.2	-2.3	-2.0	-1.9	-2.2	-2.2	-2.3	-1.9	-2.2
Qualifications: None of the above	3.8	8.1	10.1	2.6	2.8	2.5	3.2	2.8	3.2	2.7	3.1	3.1	2.3	2.9	2.6	2.9
Eye problems/disorders: Glaucoma	3.6	4.3	7.4	2.1	1.8	2.4	2.2	1.9	2.0	2.7	2.1	2.3	1.8	2.0	1.0	2.1
Pain type(s) experienced in last month: Hip pain	3.6	4.5	6.8	1.9	1.8	2.0	2.4	1.8	2.5	2.4	2.6	1.6	2.3	2.1	2.0	2.0
Type 2 Diabetes (T2D) (2018)	3.5	6.5	11.4	3.0	2.3	2.3	3.4	2.4	3.2	2.3	1.6	2.6	2.1	2.6	2.5	2.3
Glaucoma (self-reported)	3.5	4.1	7.3	2.0	1.6	2.3	2.1	1.7	2.1	2.6	2.2	2.7	1.7	1.9	0.7	2.1
Number of self-reported non-cancer illnesses	3.4	5.9	10.4	2.1	2.5	2.2	2.4	2.5	2.4	2.6	3.2	1.9	2.5	2.4	2.2	2.4
Angina (self-reported)	3.3	4.4	6.6	2.0	2.6	1.6	2.3	2.5	2.0	1.4	2.4	1.1	1.7	2.5	2.4	2.1
Loneliness, isolation	3.3	4.5	14.8	1.3	2.1	1.7	1.7	2.0	2.0	2.0	3.9	2.2	2.1	2.1	1.3	2.1
Angina	3.2	4.2	6.2	1.9	2.5	1.6	2.3	2.5	2.0	1.4	2.4	1.3	1.6	2.4	2.2	2.1
Serious illness, injury or assault to yourself	3.2	3.8	6.4	1.8	2.4	1.3	2.5	2.3	2.3	1.1	1.3	1.4	1.5	2.5	2.3	1.9
Mouth/teeth dental problems	3.2	4.9	6.6	-2.2	-2.1	-2.1	-2.4	-2.1	-2.3	-2.6	-2.6	-1.7	-2.1	-2.3	-2.0	-2.1
Neck or shoulder pain in last month	3.2	4.5	5.6	2.3	2.2	2.3	2.2	2.2	2.3	2.4	1.6	0.8	2.0	2.2	2.4	2.2
Medication: Aspirin	3.2	4.2	6.4	2.4	2.0	1.9	2.5	2.0	2.3	1.5	2.0	1.8	1.6	2.3	2.0	1.8
Eye problems/disorders: Diabetes related eye disease	3.1	3.4	4.4	1.9	1.9	1.9	1.8	2.0	1.6	2.1	1.6	1.8	2.0	1.9	1.3	2.0
Supplements: Glucosamine	3.1	4.1	6.3	-1.9	-2.3	-1.8	-1.8	-2.3	-1.9	-1.5	-2.5	-1.2	-2.2	-2.2	-2.2	-2.1
Diabetes diagnosed by doctor	3.1	5.1	9.1	2.7	2.0	2.0	3.0	2.1	2.8	1.9	1.2	2.6	1.9	2.4	2.1	2.0
Family relationship satisfaction	2.9	3.6	7.0	1.4	2.2	1.9	1.2	2.1	1.4	2.1	2.6	0.9	2.5	1.9	1.5	2.1
Osteoarthritis (self-reported)	2.9	3.7	7.2	1.8	1.6	1.9	1.8	1.7	1.8	2.7	2.5	1.7	2.4	1.6	1.2	1.8
Basal cell carcinoma (self-reported)	2.9	3.5	6.0	2.0	2.4	1.8	1.7	2.4	1.4	1.2	1.2	1.0	2.2	2.3	1.7	2.1
Blood White Count	2.8	20.8	42.8	4.5	5.3	3.9	4.5	5.2	4.3	3.3	4.0	1.2	5.1	4.8	6.5	4.5
Chronic bronchitis/emphysema (father)	2.8	3.3	4.3	2.0	2.0	1.7	2.0	2.1	1.7	1.4	1.2	1.0	2.0	2.0	1.9	2.0
Coronary Artery Disease (CAD)	2.7	3.2	5.5	0.0	0.0	-2.3	-1.8	-1.7	-2.0	-2.3	-2.2	-1.5	-1.9	-1.9	-1.6	-2.0
Number of treatments/medications taken	2.7	4.9	7.6	1.9	2.5	1.4	2.3	2.5	2.0	1.9	2.8	1.9	2.3	2.4	2.3	2.1
Average weekly red wine intake	2.7	3.9	8.4	-1.4	-1.5	-1.6	-1.8	-1.4	-2.2	-2.7	-2.9	-2.7	-1.5	-1.5	-1.9	-1.7
Smoking Status	2.6	6.1	11.0	2.3	3.0	2.0	2.1	2.9	2.2	1.7	2.6	0.6	3.2	2.5	3.3	2.6
Diabetes (father)	2.6	3.2	4.2	1.9	1.9	1.8	1.8	2.0	1.9	2.1	1.3	1.5	1.6	1.9	1.8	1.8
Illnesses of siblings	2.6	3.6	6.7	-1.7	-2.2	-1.7	-1.6	-2.3	-1.3	-2.1	-0.9	-1.9	-2.6	-2.0	-1.2	-2.2
Asthma (self-reported)	2.6	5.1	8.0	2.0	2.7	1.7	2.1	2.7	2.2	1.9	2.8	1.9	2.2	2.4	2.1	2.4
Smoking status: Current	2.6	4.2	9.9	2.2	2.3	1.9	1.8	2.2	1.8	1.2	1.8	0.1	2.5	2.1	3.1	2.0
Medication: Ramipril	2.5	3.2	5.3	2.2	1.7	2.0	2.3	1.7	1.9	1.3	0.4	2.0	1.2	2.0	1.8	1.8
Happiness	2.5	3.0	6.9	1.1	2.0	1.6	0.8	1.9	0.8	2.0	2.5	0.8	2.6	1.5	1.6	1.8
Tense / ‘highly strung’	2.5	4.2	7.2	1.5	2.1	1.9	1.7	2.0	2.0	2.4	2.7	1.7	2.5	2.0	1.9	2.0
Chronic bronchitis/emphysema (mother)	2.5	2.9	4.8	-2.0	-1.2	-2.1	-1.7	-1.2	-2.0	-2.2	-2.2	-1.4	-1.5	-1.4	-1.4	-1.5
Medication: Aspirin	2.5	3.3	5.2	2.1	1.8	1.7	2.3	1.8	2.1	1.3	1.6	1.5	1.5	2.1	1.7	1.6
High cholesterol (Self-reported)	2.5	4.4	6.2	1.9	2.1	1.7	2.5	2.0	2.4	2.4	1.9	2.4	1.8	2.3	1.9	2.0
Diabetes (self-reported)	2.4	3.8	5.9	2.4	2.0	1.8	2.4	2.0	2.2	1.7	1.3	1.2	2.0	2.2	2.0	1.7
Medication: Gliclazide	2.4	2.7	6.8	1.9	1.2	1.2	2.6	1.2	2.5	1.4	0.9	2.6	0.5	1.6	1.0	1.1
Alcohol drinker status: Never	2.4	2.9	8.8	1.4	1.3	1.3	2.1	1.3	2.2	1.8	2.1	3.0	0.7	1.5	0.7	1.5
Respiratory disease	2.3	5.1	7.1	2.2	2.7	1.8	2.1	2.7	2.0	1.9	2.2	2.0	2.3	2.4	2.4	2.4
Current tobacco smoking	2.3	3.7	8.1	2.0	2.2	1.8	1.7	2.1	1.7	1.2	1.9	0.3	2.4	2.0	2.8	1.9
Smoking status: Previous	2.3	3.5	6.5	1.6	1.9	1.5	1.7	1.9	1.9	2.1	2.5	1.6	1.8	1.8	1.3	2.0
Prostate Cancer	2.2	3.1	4.3	1.9	1.8	1.9	1.8	1.8	2.0	1.6	1.3	0.7	2.1	2.0	1.8	1.7
Alcohol usually taken with meals	2.2	3.6	6.0	-1.7	-2.0	-1.9	-1.5	-2.0	-1.6	-1.8	-2.3	-1.5	-2.4	-1.9	-1.8	-2.1
Worrier / anxious feelings	2.2	4.1	14.3	1.1	1.7	1.5	1.7	1.7	2.0	2.2	3.8	2.8	1.7	1.7	0.7	1.9
Hair/balding pattern: Pattern 4	2.1	5.1	6.9	2.4	2.5	2.2	2.2	2.5	2.0	1.8	2.6	1.2	2.5	2.4	2.0	2.4
Illnesses of father: High blood pressure	2.1	2.6	5.3	1.2	1.9	1.7	1.4	1.8	1.4	1.3	2.3	1.7	1.3	1.8	0.7	1.9
Hayfever/allergic rhinitis (self-reported)	2.0	2.6	5.0	1.8	1.5	2.0	1.7	1.6	1.7	1.5	2.2	0.9	1.2	1.8	0.7	1.7
Arm fat percentage (right)	2.0	7.9	17.1	3.1	3.0	2.2	3.4	2.9	3.2	1.6	2.0	2.1	2.3	2.9	4.1	2.6
Length of working week for main job	2.0	2.2	3.4	-1.5	-1.4	-1.4	-1.6	-1.4	-1.8	-1.7	-0.4	-1.3	-1.8	-1.5	-1.7	-1.3
Emphysema/chronic bronchitis	2.0	2.2	3.6	-1.4	-1.5	-1.6	-1.6	-1.5	-1.7	-1.2	-1.9	-1.6	-1.2	-1.7	-0.6	-1.6
Arm fat percentage (left)	2.0	8.1	16.7	3.2	3.0	2.2	3.5	3.0	3.2	1.8	1.9	2.4	2.3	2.9	4.1	2.6
Medication: Paracetamol	2.0	3.1	5.0	1.7	1.8	1.0	2.2	1.7	2.0	1.3	1.6	2.2	1.3	1.8	2.2	1.5
Qualifications: CSEs or equivalent	1.9	2.6	8.8	-1.5	-1.3	-1.8	-1.4	-1.3	-1.5	-2.0	-0.8	-3.0	-1.2	-1.5	-0.4	-1.7
Medication: Simvastatin	1.9	2.8	4.5	1.9	1.6	1.5	2.1	1.7	2.0	1.7	1.2	1.7	1.3	1.9	1.6	1.5
Asthma	1.9	3.7	6.9	1.5	2.3	1.3	1.7	2.3	1.9	1.6	2.6	1.7	1.9	2.0	1.8	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.9	2.2	5.7	-1.6	-1.3	-1.1	-1.9	-1.3	-1.8	-1.6	-0.8	-2.4	-1.0	-1.5	-1.2	-1.3
Townsend deprivation index at recruitment	1.8	2.5	4.6	-1.8	-1.1	-2.1	-1.8	-1.2	-1.8	-2.1	-0.3	-2.1	-1.0	-1.6	-0.3	-1.7
Body fat percentage	1.8	7.0	14.3	3.1	2.7	2.1	3.3	2.6	3.1	1.8	1.8	2.2	2.0	2.7	3.8	2.4
Cholesterol lowering medication	1.8	2.6	4.1	1.6	1.9	1.1	2.0	1.8	2.0	1.2	1.0	0.9	1.5	2.0	2.0	1.4
Ovarian Cancer	1.7	2.3	5.0	-2.0	-1.5	-1.3	-1.9	-1.5	-1.6	-1.1	0.3	-1.2	-1.1	-1.7	-2.2	-1.2
Waist circumference	1.7	6.1	11.9	2.7	2.6	1.9	3.2	2.5	3.0	1.5	1.7	2.0	1.7	2.6	3.4	2.3
Past tobacco smoking	1.7	3.2	5.7	-1.6	-2.0	-1.4	-1.6	-2.0	-1.8	-1.5	-2.4	-0.7	-2.0	-1.8	-2.0	-1.9
Medication: Cholesterol lowering	1.6	2.5	6.7	1.7	1.2	1.2	1.9	1.3	1.8	1.8	1.7	2.6	0.8	1.3	1.0	1.4
Wheeze or whistling in the chest in last year	1.6	2.8	7.7	1.0	1.9	1.1	1.4	1.8	1.6	1.5	2.8	1.1	1.8	1.6	1.9	1.6
Illnesses of siblings: Diabetes	1.6	2.0	3.0	1.4	1.7	1.3	1.2	1.7	1.1	1.0	1.5	0.8	1.7	1.5	1.6	1.5
Irritability	1.6	2.7	5.7	0.9	2.0	1.3	1.0	2.0	1.1	1.8	2.0	1.0	2.4	1.6	1.7	1.8
Heart attack/myocardial infarction (self-reported)	1.6	2.1	4.8	1.9	1.4	1.2	1.6	1.4	1.5	0.8	0.8	1.0	1.7	1.3	2.2	1.2
Trunk fat percentage	1.5	6.2	11.8	3.0	2.5	2.0	3.1	2.5	3.0	1.7	1.7	2.0	1.9	2.5	3.4	2.2
Qualifications: O levels/GCSEs or equivalent	1.5	2.4	4.4	-1.6	-1.4	-1.6	-1.5	-1.4	-1.6	-1.9	-2.1	-1.6	-1.2	-1.3	-1.0	-1.6
Trunk fat mass	1.4	5.9	11.7	2.9	2.4	2.0	3.1	2.4	2.9	1.7	1.4	2.1	1.8	2.4	3.4	2.2
Age when periods started (menarche)	1.3	3.0	6.6	1.6	1.4	1.9	1.5	1.5	1.8	2.6	1.9	2.1	1.5	1.5	0.7	1.8
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	2.8	-1.2	-1.4	-1.4	-0.9	-1.4	-0.8	-1.2	-0.3	-1.2	-1.7	-1.3	-0.8	-1.5
Illnesses of mother	1.3	1.6	4.3	-1.3	-1.7	-1.0	-1.0	-1.6	-0.4	-0.3	0.9	-1.0	-1.5	-1.5	-2.1	-1.3
Gout (self-reported)	1.3	1.8	2.8	1.1	1.4	1.0	1.2	1.3	1.4	1.6	1.5	1.4	1.4	1.1	1.7	1.3
Qualifications: College or University degree	1.3	4.3	7.0	-2.0	-2.1	-2.0	-2.3	-2.0	-2.5	-1.6	-1.8	-1.6	-1.7	-2.1	-2.6	-2.1
Mouth/teeth dental problems: Loose teeth	1.3	1.6	2.6	1.2	1.2	1.3	1.5	1.2	1.5	1.3	1.6	0.9	0.8	1.4	0.9	1.3
Suffer from ‘nerves’	1.3	2.1	5.1	-1.9	-1.7	-1.6	-1.1	-1.7	-0.8	-0.8	0.4	-0.1	-1.7	-1.4	-2.3	-1.6
Stomach or abdominal pain in last month	1.2	1.5	2.7	1.2	1.4	1.1	1.3	1.4	1.0	1.1	0.6	0.4	1.7	1.4	1.4	1.2
Heart attack	1.2	1.5	3.8	1.6	1.2	1.0	1.3	1.2	1.3	0.7	0.6	0.6	1.5	1.1	2.0	1.0
Pain all over the body in last month	1.2	1.3	3.3	1.1	0.9	0.9	1.1	0.9	1.2	1.8	1.8	1.3	0.9	0.8	0.9	0.9
Arm fat mass (right)	1.2	4.8	12.4	2.5	2.3	1.5	2.8	2.2	2.6	1.1	0.9	1.7	1.6	2.3	3.5	1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	6.2	1.1	1.1	0.5	1.5	1.1	1.5	0.9	1.5	2.5	0.3	1.0	0.6	1.1
Heart disease (mother)	1.2	1.5	2.0	1.3	1.4	1.1	1.1	1.4	0.8	1.1	0.7	1.3	1.4	1.4	1.1	1.3
Whole body fat mass	1.2	5.0	11.7	2.7	2.2	1.7	2.9	2.2	2.7	1.4	1.2	1.8	1.7	2.2	3.4	2.0
Chest pain or discomfort	1.2	1.7	5.7	0.7	1.4	0.5	1.3	1.3	1.4	1.0	2.4	1.3	0.8	1.1	1.7	1.0
Had major operations	1.2	1.4	3.5	-1.0	-1.2	-1.3	-0.6	-1.3	-0.8	-1.9	-1.2	-0.4	-1.7	-0.9	-0.9	-1.4
Supplements: Vitamin C	1.2	1.4	2.2	-1.4	-1.2	-1.2	-1.3	-1.3	-1.2	-1.0	-0.3	-1.0	-1.5	-1.3	-1.1	-1.3
Arm fat mass (left)	1.2	4.8	12.1	2.6	2.3	1.6	2.9	2.2	2.6	1.1	0.9	1.8	1.6	2.3	3.5	1.9
Leg fat percentage (left)	1.2	4.2	9.1	2.5	1.8	1.6	2.7	1.8	2.5	1.6	1.2	2.0	1.4	1.9	3.0	1.8
Leg fat mass (left)	1.2	4.5	10.6	2.5	2.0	1.7	2.8	2.0	2.6	1.5	0.8	1.8	1.5	2.1	3.3	1.9
Blood Platelet Count	1.1	12.4	15.7	3.7	4.0	3.5	3.6	4.0	3.2	2.7	3.0	3.2	3.6	3.9	3.5	3.9
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	6.6	-1.3	-0.6	-1.2	-1.3	-0.7	-0.9	-1.4	0.1	-2.6	-0.6	-0.9	-0.2	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.5	6.2	-1.5	-1.6	-1.5	-1.9	-1.6	-2.1	-2.4	-2.5	-2.5	-1.6	-1.6	-1.3	-1.7
Medication: Ventolin 100micrograms inhaler	1.1	1.4	6.6	0.7	1.3	1.0	0.9	1.3	1.0	0.7	2.6	0.3	0.9	1.3	0.5	1.3
Leg fat mass (right)	1.1	4.2	10.4	2.4	2.0	1.6	2.6	1.9	2.4	1.4	1.0	1.7	1.6	2.0	3.2	1.8
Supplements: Zinc	1.0	1.1	2.9	-1.3	-1.2	-0.9	-0.9	-1.2	-0.8	0.2	-1.4	-0.2	-0.8	-1.0	-1.7	-1.0
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.5	7.5	0.3	1.3	0.5	0.7	1.3	1.1	0.9	2.7	0.6	1.5	1.2	0.6	1.1
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	3.7	-0.8	-0.9	-1.2	-0.8	-0.9	-1.2	-1.9	-1.2	-0.6	-1.4	-0.9	-0.9	-1.0
Forced expiratory volume in 1-second (FEV1)	1.0	3.4	6.7	-1.5	-1.6	-1.2	-2.0	-1.6	-2.0	-2.1	-2.4	-2.6	-1.5	-1.7	-1.6	-1.6
Financial situation satisfaction	1.0	1.3	7.4	-0.1	1.1	0.2	0.5	1.0	0.9	1.3	2.7	0.7	1.1	0.7	1.2	0.8
Pain experienced in last month	1.0	1.6	2.9	-1.1	-1.1	-1.2	-1.2	-1.0	-1.3	-1.6	-1.7	-1.0	-1.1	-1.0	-1.6	-1.2
Heart disease (siblings)	1.0	1.2	1.9	1.0	1.2	1.0	1.1	1.2	0.9	1.4	1.0	1.0	1.3	1.1	0.8	1.2
Alzheimer’s Disease (in mother)	0.9	1.1	2.3	1.0	0.9	1.0	1.5	0.9	1.3	0.8	0.2	1.5	0.6	1.2	0.9	1.0
Crohns Disease (2017)	0.9	1.9	8.6	1.3	0.7	1.4	1.2	0.7	1.4	1.8	1.5	2.9	0.9	1.0	0.1	1.3
Diabetes (mother)	0.9	1.1	2.9	1.0	0.8	0.9	1.1	0.8	1.0	1.3	1.4	1.7	0.7	0.8	0.7	0.8
Medication: Levothyroxine sodium	0.9	1.5	3.3	-1.3	-1.4	-1.8	-1.0	-1.4	-1.0	-1.0	-0.3	-0.1	-1.2	-1.5	-1.3	-1.5
Body mass index (BMI)	0.9	3.9	10.9	2.1	2.0	1.3	2.6	2.0	2.3	0.9	0.8	1.7	1.4	2.0	3.3	1.7
Lung cancer (father)	0.9	1.0	3.3	1.3	1.0	0.7	1.2	1.0	1.3	0.4	0.5	-0.2	0.9	1.0	1.8	0.7
Peak expiratory flow (PEF)	0.9	2.1	7.2	-1.2	-0.9	-1.1	-1.5	-1.0	-1.4	-2.1	-1.7	-2.7	-1.0	-1.1	-0.3	-1.2
Loud music exposure frequency	0.9	1.0	3.5	0.8	0.6	1.4	0.7	0.5	1.0	1.9	1.4	0.9	0.8	0.6	0.8	0.9
Mouth/teeth dental problems: Bleeding gums	0.9	1.1	2.2	1.1	0.9	1.0	1.2	0.9	1.3	1.5	1.5	0.1	0.8	1.0	0.9	0.8
Leg fat percentage (right)	0.9	3.4	8.3	2.1	1.7	1.4	2.3	1.6	2.2	1.4	1.3	1.7	1.4	1.6	2.9	1.6
Hypertension (Self-reported)	0.9	2.6	6.9	1.4	1.6	1.1	1.9	1.6	1.7	1.2	1.3	2.6	1.0	1.6	1.2	1.7
Breast Cancer	0.8	1.9	6.9	0.8	0.9	0.9	1.3	0.9	1.6	1.8	2.0	2.6	0.9	1.0	0.3	1.2
HbA1C	0.8	0.9	2.4	0.6	1.3	0.5	0.6	1.3	0.6	-0.1	0.7	-0.6	1.2	1.1	1.5	0.9
Blood Eosinophil Count	0.8	6.5	13.5	2.4	3.1	1.7	2.6	3.0	2.6	1.9	2.0	1.8	2.4	2.8	3.7	2.5
Lung FVC	0.8	4.0	6.7	-1.4	-2.0	-1.4	-1.9	-2.0	-2.3	-2.5	-2.6	-1.7	-2.1	-1.8	-2.0	-1.9
Relative age of first facial hair	0.8	1.5	3.1	-1.5	-1.3	-0.8	-1.5	-1.3	-1.1	-0.9	-0.1	-1.8	-1.1	-1.2	-1.6	-1.2
Hayfever, allergic rhinitis or eczema	0.8	1.7	3.0	1.7	1.5	1.0	1.6	1.5	1.6	0.8	0.6	0.8	0.9	1.4	1.7	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	4.5	0.6	0.9	0.7	1.4	0.9	1.6	1.0	2.1	1.3	0.6	1.0	0.1	1.0
Exposure to tobacco smoke outside home	0.8	1.0	3.8	0.7	1.1	0.7	1.1	1.0	1.0	0.2	-0.4	1.9	0.5	1.1	0.9	1.1
Age at first live birth	0.8	1.4	2.6	-1.2	-1.1	-1.2	-1.0	-1.1	-1.0	-1.6	-1.2	-0.8	-1.5	-0.9	-1.4	-1.1
Shortness of breath walking on level ground	0.8	1.0	3.6	0.4	1.3	0.3	0.7	1.1	0.8	0.2	1.9	0.3	1.0	0.9	1.6	0.8
Medication: Blood pressure	0.8	1.5	2.7	1.2	1.2	1.0	1.3	1.3	1.2	1.2	1.3	1.6	0.9	1.2	1.0	1.3
Average weekly champagne plus white wine intake	0.8	1.1	4.4	1.1	0.8	1.0	1.2	0.8	1.1	1.1	-0.2	2.1	0.5	0.9	0.9	1.0
Diastolic blood pressure, automated reading	0.8	2.4	6.2	-1.4	-1.0	-0.9	-2.0	-1.1	-2.1	-1.6	-2.2	-2.5	-0.4	-1.3	-1.0	-1.1
Ever depressed for a whole week	0.8	1.0	3.1	1.4	1.0	0.8	1.2	1.0	0.9	0.3	0.5	0.2	0.9	0.9	1.8	0.8
Vascular/heart problems diagnosed by doctor	0.8	2.3	5.0	-1.3	-1.7	-1.1	-1.6	-1.7	-1.4	-1.0	-1.3	-2.2	-1.1	-1.6	-1.3	-1.7
Worry (Nagel 2018)	0.7	1.5	5.5	0.6	0.4	1.1	1.1	0.3	1.4	1.7	2.3	2.3	0.5	0.6	0.0	0.8
HDL Cholesterol	0.7	1.2	2.2	-1.0	-1.2	-1.1	-0.7	-1.2	-0.7	-1.1	-1.5	-0.6	-1.4	-1.0	-1.2	-1.3
LDL Cholesterol	0.7	1.1	2.9	-0.9	-0.9	-1.1	-1.0	-0.9	-1.1	-1.2	-1.7	-0.8	-1.0	-1.0	-0.5	-1.0
Father’s age at death	0.7	0.9	3.2	0.9	0.5	1.0	1.1	0.5	1.4	1.8	0.3	1.1	0.7	0.7	0.5	0.7
Hair/balding pattern: Pattern 3	0.7	1.1	7.3	-0.8	-1.0	-0.9	-0.3	-1.0	-0.5	-0.7	-2.7	-0.5	-0.4	-0.6	-0.6	-1.1
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	3.0	-1.1	-1.0	-0.7	-1.3	-1.0	-1.1	-1.0	-1.3	-1.7	-0.5	-1.0	-0.7	-1.0
Forced vital capacity (FVC), Best measure	0.7	2.7	4.8	-1.4	-1.3	-1.4	-1.8	-1.3	-1.9	-2.0	-1.5	-2.2	-1.6	-1.4	-1.7	-1.5
Worry too long after embarrassment	0.7	1.2	8.2	0.2	-0.0	0.7	0.4	-0.0	0.9	1.3	2.9	1.8	0.1	0.1	-0.7	0.4
Medication: Allopurinol	0.7	1.0	2.5	1.0	0.5	0.8	1.0	0.5	1.2	1.5	1.1	1.6	0.7	0.5	1.2	0.7
Medication: Omeprazole	0.7	0.8	3.9	0.5	0.8	0.5	0.8	0.8	0.8	1.0	2.0	0.5	0.8	0.7	1.1	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	2.7	-1.4	-1.3	-1.2	-1.2	-1.3	-1.2	-0.7	-0.4	-1.6	-1.3	-1.3	-1.1	-1.4
Long-standing illness, disability or infirmity	0.7	1.1	4.9	0.7	1.2	0.2	0.7	1.2	0.7	0.5	2.2	-0.1	0.9	0.9	1.5	0.7
Qualifications: nursing, teaching	0.7	1.1	2.1	-0.9	-1.3	-1.0	-0.9	-1.2	-1.0	-0.8	-1.0	-0.4	-1.5	-1.1	-1.4	-1.1
Mineral and other dietary supplements	0.7	0.9	2.2	1.0	1.1	0.9	0.8	1.0	0.7	0.5	1.0	0.8	1.0	0.8	1.5	1.0
Guilty feelings	0.7	1.0	6.7	-0.1	0.3	0.2	0.4	0.3	0.7	1.0	2.6	1.9	0.6	0.3	-0.7	0.6
Wears glasses or contact lenses	0.7	0.8	3.4	0.7	0.5	0.8	1.1	0.5	1.4	0.9	0.3	1.8	0.2	0.7	0.3	0.8
Alcohol drinker status: Previous	0.7	0.8	1.6	-1.1	-0.8	-1.2	-0.6	-0.8	-0.7	-1.1	-1.3	-0.5	-0.8	-0.8	-0.9	-1.0
Depressed Affect (Nagel 2018)	0.6	1.2	6.3	0.2	0.4	1.0	0.7	0.3	0.9	1.4	2.5	1.6	1.2	0.6	0.0	0.9
Neuroticism (Nagel 2018)	0.6	1.4	7.9	0.1	-0.1	0.9	0.5	-0.1	0.9	1.6	2.8	2.0	0.7	0.2	-0.6	0.6
Alzheimer’s Disease (including proxy)	0.6	0.9	2.0	0.9	0.9	0.8	1.3	0.8	1.3	0.6	-0.1	1.4	0.5	1.1	1.0	0.9
Medication for hormone replacement therapy	0.6	0.7	1.4	-1.0	-0.6	-1.0	-0.9	-0.7	-0.9	-0.7	-0.0	-1.2	-0.9	-0.9	-0.5	-0.8
High blood pressure	0.6	1.6	5.2	1.0	1.4	0.8	1.4	1.4	1.2	0.8	0.9	2.3	0.7	1.3	0.9	1.4
High blood pressure (mother)	0.6	0.8	5.3	-0.6	-0.2	-0.6	-0.8	-0.3	-1.0	-1.0	-2.3	-1.1	0.1	-0.5	0.6	-0.6
Had other major operations	0.6	0.7	1.8	0.6	0.6	0.8	0.5	0.5	0.7	1.2	1.3	1.3	0.5	0.4	0.9	0.8
Forced vital capacity (FVC)	0.6	2.3	4.9	-1.2	-1.4	-0.9	-1.8	-1.3	-1.8	-1.5	-1.6	-2.2	-1.2	-1.4	-1.8	-1.2
Neuroticism score	0.6	1.2	9.0	-0.3	0.4	0.2	0.3	0.4	0.8	1.1	3.0	1.9	0.6	0.3	-0.3	0.5
Weight	0.6	2.8	7.0	1.9	1.6	1.1	2.3	1.6	2.1	0.9	0.6	1.4	1.1	1.8	2.6	1.4
Medication: Paracetamol	0.6	1.0	4.3	0.7	0.7	0.2	1.4	0.7	1.3	0.6	1.1	2.1	0.2	0.8	1.2	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	3.7	-0.9	-0.6	-0.6	-1.1	-0.6	-0.9	-0.4	0.6	-1.9	-0.1	-0.8	-0.8	-0.6
Ever had bowel cancer screening	0.6	0.7	1.5	-0.5	-1.2	-0.7	-0.5	-1.2	-0.6	-0.8	-0.5	0.3	-1.1	-1.0	-1.1	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	4.3	-0.9	-1.2	-0.9	-0.8	-1.2	-0.8	-1.1	-2.1	-0.9	-1.4	-1.1	-0.6	-1.2
Triglycerides	0.5	0.9	3.3	0.5	1.1	0.7	0.5	1.1	0.5	0.3	1.8	0.3	1.2	1.1	0.8	1.0
BMI	0.5	2.8	7.6	1.7	1.6	1.1	2.2	1.6	2.1	0.9	0.7	1.3	1.3	1.7	2.8	1.4
Allergy or Eczema	0.5	1.3	2.5	1.6	1.3	0.8	1.4	1.3	1.3	0.6	-0.1	0.9	0.7	1.2	1.5	1.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	4.2	-0.1	0.8	0.2	0.3	0.7	0.5	0.5	2.1	0.9	0.9	0.7	-0.0	0.7
Ever used hormone-replacement therapy (HRT)	0.5	0.6	2.6	0.4	0.9	0.1	0.8	0.9	0.8	0.7	1.6	0.5	0.2	0.7	0.3	0.7
Pack years adult smoking proportion	0.5	0.8	1.5	-0.9	-0.5	-1.2	-0.9	-0.6	-0.9	-1.1	-0.8	-1.0	-0.8	-0.8	0.7	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	5.2	-0.1	0.6	0.2	0.2	0.6	0.3	0.7	2.3	0.7	0.9	0.5	-0.2	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	3.1	-0.5	-1.3	-1.2	-0.4	-1.3	-0.6	-1.2	-1.8	-0.2	-1.6	-0.9	-0.7	-1.4
Hair/balding pattern: Pattern 2	0.5	0.7	1.7	-0.9	-1.0	-0.6	-0.9	-0.9	-0.6	-0.3	0.7	-0.4	-0.8	-1.0	-1.3	-0.7
Alcohol intake versus 10 years previously	0.5	0.8	2.0	0.7	0.8	0.5	1.2	0.8	1.3	0.9	1.4	0.6	0.5	0.9	0.5	0.8
High blood pressure (siblings)	0.5	0.8	3.0	0.4	0.7	0.5	0.6	0.8	0.4	1.2	-0.9	1.7	1.2	0.6	0.3	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.8	-0.8	-0.7	-0.5	-0.8	-0.7	-0.7	-0.2	-0.8	-1.3	-0.1	-0.7	-1.0	-0.6
Medication for pain relief, constipation, heartburn	0.5	0.9	2.9	-0.7	-0.8	-0.4	-1.1	-0.7	-1.1	-0.5	-1.7	-0.8	-0.3	-0.8	-1.7	-0.5
Mother’s age at death	0.5	0.7	1.6	-0.8	-1.0	-0.8	-0.3	-1.0	-0.4	-0.8	-0.3	-0.6	-1.3	-0.7	-1.2	-1.0
Medication: Blood pressure	0.5	0.9	2.7	1.0	1.1	0.6	1.1	1.1	0.8	0.1	-0.5	0.6	0.8	1.1	1.7	0.8
Medication: Lisinopril	0.5	0.6	2.9	1.0	0.9	0.6	0.8	0.8	0.7	0.1	0.2	0.0	0.6	0.7	1.7	0.7
Unable to work because of sickness or disability	0.5	0.7	1.7	0.0	0.9	0.2	0.3	0.8	0.5	1.0	1.3	1.0	1.1	0.7	0.9	0.7
Pack years of smoking	0.5	0.7	1.2	-0.9	-0.5	-1.1	-0.9	-0.7	-0.9	-0.8	-0.9	-0.9	-0.6	-0.8	0.5	-0.9
Irritable Bowel Disease (IBD)	0.4	0.9	3.9	0.8	0.5	0.8	0.7	0.5	0.8	0.7	1.7	2.0	0.2	0.7	0.1	0.8
Neuroticism (2016)	0.4	0.6	5.5	-0.5	0.7	-0.4	-0.2	0.6	-0.2	-0.1	2.3	0.2	0.5	0.3	0.0	0.4
Waist Hip Ratio (WHR)	0.4	1.8	2.9	1.5	1.7	1.1	1.5	1.7	1.3	1.0	1.3	0.7	1.1	1.5	1.3	1.5
Neuroticism	0.4	1.0	8.2	-0.6	-0.0	0.3	0.0	-0.1	0.4	1.2	2.9	1.2	0.4	0.1	-0.9	0.3
Sensitivity / hurt feelings	0.4	0.7	1.1	-0.9	-0.7	-0.8	-1.0	-0.7	-0.8	-0.9	0.7	-0.8	-0.7	-0.9	-0.8	-0.8
Relative age voice broke	0.4	0.5	1.2	-1.1	-0.7	-0.6	-1.1	-0.7	-0.8	-0.3	0.2	-0.5	-0.7	-0.8	-0.9	-0.7
Allergy	0.4	0.9	1.9	-1.0	-1.4	-0.3	-1.1	-1.4	-1.0	-0.4	-0.7	-0.0	-0.7	-1.2	-1.4	-0.8
Hip circumference	0.4	1.5	4.3	1.4	1.1	0.7	1.9	1.1	1.7	0.5	0.5	0.9	0.6	1.3	2.1	0.9
Number of live births	0.4	0.5	1.5	0.4	0.7	0.2	0.5	0.7	0.7	1.1	1.2	0.7	0.7	0.4	0.6	0.6
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.2	0.6	1.1	0.6	0.4	1.0	0.1	0.2	0.3	-0.6	0.7	0.9	1.1	0.7
Migraine (self-reported)	0.4	0.5	1.7	-0.4	-0.5	-0.5	-0.7	-0.4	-0.8	-0.8	-0.8	-1.3	-0.1	-0.6	-0.5	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.5	-0.6	-0.9	-0.3	-0.4	-0.9	-0.5	-0.4	-1.2	0.1	-0.9	-0.7	-0.5	-0.7
Overall health rating	0.4	0.9	3.6	-0.0	1.2	-0.4	0.5	1.1	0.3	0.5	1.9	-0.1	1.1	0.7	1.5	0.4
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	3.6	0.2	-0.5	0.2	-0.4	-0.4	-0.6	0.1	-1.9	0.7	0.1	-0.4	-0.9	-0.1
Mood swings	0.4	0.7	3.2	-0.2	0.8	-0.0	0.3	0.8	0.4	0.7	1.8	1.0	1.2	0.5	0.4	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	0.8	0.2	0.8	0.2	0.7	0.7	0.6	0.9	0.9	0.7	0.8	0.7	0.5	0.7
Commuting to job workplace: Walk	0.4	0.5	0.8	-0.8	-0.8	-0.9	-0.1	-0.8	-0.1	-0.5	-0.8	0.6	-0.9	-0.5	-0.8	-0.6
Medication for cholesterol	0.4	0.6	2.1	-0.7	-1.1	-0.3	-0.6	-1.0	-0.5	0.0	-0.3	0.5	-0.6	-0.8	-1.5	-0.6
Miserableness	0.4	0.8	3.8	-1.2	-0.5	-1.1	-0.8	-0.5	-0.4	-0.4	1.9	-0.7	-0.3	-0.7	-0.6	-0.7
Medication: Bendroflumethiazide	0.4	0.7	1.1	0.8	0.8	0.8	0.8	0.9	0.7	0.9	0.4	1.1	1.0	0.9	0.1	0.9
Average weekly beer plus cider intake	0.4	0.6	3.1	-1.2	-0.5	-0.3	-1.2	-0.6	-0.8	-0.2	0.2	-1.8	0.5	-0.6	-0.2	-0.5
Ever had prostate specific antigen (PSA) test	0.4	0.5	0.9	-0.4	-0.8	-0.2	-0.8	-0.9	-0.9	-0.5	0.0	-0.8	-0.7	-0.8	-0.1	-0.9
Cardiovascular Disease	0.3	0.9	1.9	1.0	1.1	0.6	1.4	1.1	1.2	0.5	0.5	0.9	0.4	1.2	0.9	0.9
Hearing difficulty/problems: Yes	0.3	0.5	1.1	-0.9	-0.6	-1.0	-0.9	-0.6	-0.8	-0.3	0.1	0.5	-0.7	-0.9	-0.3	-0.8
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.7	-0.5	-0.8	-0.6	-0.6	-0.7	-0.7	-0.3	0.5	-0.7	-0.7	-0.8	-0.6	-0.8
Fed-up feelings	0.3	0.5	4.0	-0.5	0.2	-0.1	-0.1	0.2	0.2	0.5	2.0	1.4	0.4	0.1	-0.3	0.3
Multivitamins +/- minerals	0.3	0.4	0.8	0.5	0.9	0.5	0.7	0.9	0.6	0.7	-0.0	0.4	0.5	0.9	0.4	0.8
Number of incorrect matches in round	0.3	0.6	1.1	0.8	0.7	1.0	0.7	0.6	0.8	0.6	0.5	0.6	0.8	0.8	1.0	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.9	-0.3	-1.0	-1.0	-0.0	-0.9	-0.2	-0.6	-1.2	0.6	-1.4	-0.7	-0.6	-1.0
Financial difficulties in last 2 years	0.3	0.4	1.5	-0.8	-0.6	-0.9	-0.4	-0.7	-0.1	-0.4	1.2	0.3	-0.7	-0.7	-0.5	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.6	-1.3	-0.3	-1.1	-0.6	-0.5	-0.5	-0.2	1.0	0.8	-0.5	-0.6	-0.4	-0.5
Falls in the last year	0.3	0.4	3.2	0.3	0.6	0.6	0.3	0.5	0.3	0.3	1.8	0.2	0.7	0.5	0.4	0.6
Exposure to tobacco smoke at home	0.3	0.3	2.9	0.4	0.2	0.1	0.7	0.2	0.6	0.1	0.1	1.7	-0.3	0.4	-0.1	0.2
Pulse wave reflection index	0.3	0.4	2.7	-0.5	-0.4	-0.4	-0.8	-0.4	-0.7	-0.3	-0.5	-1.6	0.0	-0.5	0.1	-0.5
Medication: Amlodipine	0.3	0.5	1.1	-0.4	-0.7	-0.6	-0.7	-0.7	-1.0	-0.6	-0.9	-0.7	-0.5	-0.8	-0.1	-0.8
Pulse wave peak to peak time	0.3	0.4	1.2	-0.3	-0.6	-0.5	-0.1	-0.6	0.1	-0.4	-0.1	1.0	-1.1	-0.4	-1.0	-0.5
Health satisfaction	0.3	0.4	2.0	-0.5	0.6	-0.4	-0.4	0.5	-0.4	-0.0	1.4	-0.3	0.8	0.1	0.8	0.2
Medication: Ibuprofen	0.3	0.3	0.9	0.0	0.5	0.3	0.6	0.4	0.7	0.6	0.9	0.9	0.5	0.6	0.5	0.5
Number of full sisters	0.3	0.3	1.8	-0.3	0.3	0.2	-0.4	0.2	0.0	0.6	1.3	-0.7	0.7	0.0	0.7	0.1
Leg pain on walking	0.3	0.3	2.2	-0.4	0.2	-0.0	-0.6	0.1	-0.1	0.7	1.5	-0.4	0.7	-0.3	0.4	0.2
Friendships satisfaction	0.3	0.4	2.3	-0.4	0.1	-0.1	-1.0	-0.0	-0.7	-0.1	0.5	-1.5	0.4	-0.3	0.5	-0.2
Eye problems/disorders: Cataract	0.3	0.4	0.9	0.5	0.5	0.3	0.8	0.5	1.0	0.0	0.8	-0.1	0.7	0.7	0.8	0.4
Back pain experienced in last month	0.3	0.5	1.1	-1.0	-0.6	-0.8	-0.9	-0.7	-0.8	-0.2	0.3	-1.1	-0.0	-0.9	0.1	-0.6
Age started oral contraceptive pill	0.3	0.4	2.2	0.2	-0.6	0.1	0.3	-0.5	0.2	0.4	-0.3	0.9	-0.8	-0.2	-1.5	-0.1
Supplements: Calcium	0.3	0.3	0.6	0.6	0.6	0.6	0.6	0.6	0.6	0.7	0.1	0.5	0.3	0.6	0.6	0.5
Reaction Time	0.2	0.3	0.7	-0.8	-0.5	-0.9	-0.6	-0.5	-0.6	0.3	0.1	0.5	-0.4	-0.7	-0.5	-0.5
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.5	1.0	0.4	1.2	0.7	0.5	0.6	0.7	0.4	0.5	0.5	0.7	0.2	0.7
Body Mass Index (BMI) (2010)	0.2	0.3	1.5	0.1	0.5	-0.1	-0.1	0.4	0.0	-0.2	-0.3	-1.1	0.7	0.2	1.2	0.1
Blood Red Count	0.2	1.5	7.8	-0.3	0.7	-0.6	-1.1	0.5	-1.3	-0.7	-1.6	-2.8	0.8	-0.3	2.1	-0.3
Heel T-Score	0.2	1.8	3.8	-0.9	-1.3	-1.7	-0.8	-1.3	-1.2	-1.6	-1.8	-0.1	-2.0	-1.2	-0.9	-1.6
Hypothyroidism (self reported)	0.2	0.5	1.4	-0.7	-0.7	-1.1	-0.5	-0.7	-0.7	-0.7	-1.2	0.1	-0.3	-0.8	-0.6	-0.7
Lung FEV1/FVC ratio	0.2	1.2	6.7	-1.1	-1.0	-0.5	-1.1	-1.1	-0.7	-0.9	-2.6	-1.2	-0.2	-1.0	0.2	-0.9
Average weekly spirits intake	0.2	0.2	0.5	0.6	0.6	0.4	0.1	0.6	-0.0	0.0	0.2	0.1	0.7	0.4	0.6	0.6
Leg fat-free mass (left)	0.2	0.8	3.2	1.0	0.8	0.5	1.3	0.7	1.2	0.3	-0.3	0.5	0.5	0.9	1.8	0.6
Hand grip strength (right)	0.2	0.7	3.1	-0.7	-0.7	-0.1	-0.6	-0.7	-0.4	-0.2	-1.8	-1.4	-0.1	-0.4	-0.9	-0.5
Taking other prescription medications	0.2	0.3	1.6	0.4	0.4	0.0	0.8	0.4	0.6	0.5	1.3	0.8	0.2	0.4	0.3	0.3
Nervous feelings	0.2	0.3	2.6	-0.4	-0.4	-0.3	-0.1	-0.4	0.3	0.3	1.6	0.3	-0.4	-0.3	-0.6	-0.5
Hearing difficulty/problems with background noise	0.2	0.3	1.6	0.4	0.5	0.3	0.3	0.5	0.4	0.4	1.3	0.6	0.5	0.2	0.5	0.5
Pulse rate	0.2	0.4	0.9	-0.8	-0.7	-0.6	-0.8	-0.7	-0.7	0.0	0.4	0.0	-0.6	-0.9	-0.3	-0.6
Noisy workplace	0.2	0.2	0.6	-0.8	-0.4	-0.6	-0.7	-0.5	-0.3	-0.6	0.2	0.1	-0.5	-0.6	-0.1	-0.3
Medication: Lansoprazole	0.2	0.2	0.6	0.6	0.4	-0.0	0.7	0.4	0.4	0.1	0.5	0.2	-0.0	0.4	0.7	0.1
Prospective memory result	0.2	0.2	1.1	-0.1	0.3	0.1	-0.6	0.2	-0.5	-0.1	0.3	-1.0	0.9	-0.2	0.8	0.0
Pulse wave Arterial Stiffness index	0.2	0.3	1.2	0.2	0.4	0.4	-0.1	0.4	-0.2	0.3	-0.1	-1.1	0.9	0.2	0.8	0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	1.2	-0.7	-0.8	-1.1	-0.3	-0.8	-0.3	-0.6	-0.7	0.3	-0.6	-0.9	-0.4	-0.8
Number of full brothers	0.2	0.2	0.7	0.3	0.4	0.4	0.2	0.4	0.5	0.6	0.3	0.2	0.8	0.3	0.8	0.4
Medication: Seretide 50 evohaler	0.2	0.2	1.1	0.3	0.6	0.2	0.2	0.7	-0.0	0.4	0.5	0.0	1.0	0.5	0.5	0.5
Mean time to correctly identify matches	0.2	0.5	1.0	-0.7	-0.7	-0.7	-0.6	-0.7	-0.6	0.5	0.4	1.0	-0.4	-0.9	-0.9	-0.5
Pulse rate, automated reading	0.2	0.8	1.6	0.9	0.6	0.8	1.0	0.6	1.1	1.0	1.0	0.9	0.7	0.7	1.3	0.6
Alcohol intake frequency.	0.2	0.6	2.0	0.3	0.3	-0.4	1.4	0.2	1.2	-0.2	0.5	1.4	-0.7	0.5	0.7	0.0
Leg fat-free mass (right)	0.2	0.9	3.0	1.1	0.7	0.5	1.4	0.7	1.3	0.4	-0.5	0.7	0.3	1.0	1.7	0.6
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.7	0.4	0.4	0.2	0.7	0.4	0.8	-0.3	0.1	0.7	-0.2	0.5	0.5	0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.5	-0.2	-0.7	-0.6	-0.4	-0.6	-0.7	-0.4	-0.7	0.6	-0.7	-0.6	-0.5	-0.6
Osteoporosis (self-reported)	0.2	0.2	0.8	0.0	-0.2	0.3	0.4	-0.1	0.9	0.6	0.7	0.6	-0.2	0.0	-0.5	0.2
Leg predicted mass (right)	0.2	0.8	2.8	1.0	0.7	0.5	1.4	0.7	1.3	0.4	-0.4	0.6	0.4	1.0	1.7	0.6
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.7	0.2	0.4	0.3	0.6	0.4	0.7	0.4	0.8	0.5	0.2	0.7	-0.4	0.4
Ever smoked	0.2	0.3	1.1	-0.0	0.4	-0.4	-0.1	0.4	0.0	-0.4	1.0	-1.0	0.6	0.0	0.9	0.1
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	2.3	-0.1	0.3	-0.1	0.1	0.3	0.3	0.5	1.5	-0.0	0.5	0.1	0.8	0.2
Depression (Nagel 2018)	0.1	0.2	1.1	-0.4	-0.5	0.0	-0.3	-0.5	-0.3	0.2	0.7	0.4	0.2	-0.3	-1.1	-0.1
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.7	0.6	0.3	0.8	0.1	0.4	-0.0	0.3	0.1	0.7	0.3	0.4	-0.2	0.6
Alzheimer’s Disease (in father)	0.1	0.1	0.2	-0.2	0.2	-0.3	-0.1	0.2	0.1	-0.1	-0.2	0.5	0.2	0.0	0.5	0.0
Ulcerative Colitis (UC)	0.1	0.1	0.6	0.3	0.1	0.1	0.3	0.1	0.2	-0.4	0.5	0.8	-0.3	0.2	0.2	0.2
Age at First Birth	0.1	0.1	0.4	-0.6	0.2	-0.4	-0.3	0.1	-0.2	-0.1	0.4	-0.1	0.0	0.1	-0.5	0.0
Fasting Glucose	0.1	0.1	0.4	0.2	0.4	0.2	-0.3	0.4	0.1	-0.3	0.3	-0.5	0.5	0.1	0.6	0.3
Lupus	0.1	0.2	0.9	0.3	-0.3	0.1	-0.1	-0.2	-0.5	0.2	0.5	0.9	-0.4	-0.2	-0.7	-0.0
Primary Biliary Cirrhosis	0.1	0.1	0.3	-0.5	-0.0	-0.3	-0.4	-0.1	-0.1	-0.2	0.4	-0.5	0.2	-0.0	-0.2	-0.3
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.4	0.2	0.2	-0.2	0.4	0.2	0.6	-0.3	-0.3	-0.7	-0.2	0.2	0.5	-0.0
Systolic Blood Pressure	0.1	0.3	1.8	0.0	0.3	0.4	-0.1	0.3	0.0	-0.2	-1.3	-1.2	0.6	0.3	-0.1	0.2
Hand grip strength (left)	0.1	0.3	2.4	0.3	0.0	0.6	0.1	0.1	0.3	-0.0	-1.6	-0.9	-0.0	0.3	0.1	0.1
Ever had hysterectomy (womb removed)	0.1	0.1	0.7	-0.0	-0.0	0.1	-0.4	0.0	-0.4	0.1	0.8	-0.4	0.1	-0.2	-0.4	0.0
Systolic blood pressure, automated reading	0.1	0.2	0.7	0.6	0.3	0.8	0.3	0.3	0.4	0.2	-0.8	0.0	0.6	0.4	0.2	0.5
Vitamin and mineral supplements	0.1	0.1	0.3	0.5	0.2	0.3	0.2	0.2	0.1	0.1	0.4	0.1	0.5	0.2	0.3	0.2
Medication: Co-codamol	0.1	0.1	0.4	-0.3	0.1	-0.4	0.1	0.1	0.3	0.2	0.3	-0.4	0.3	-0.1	0.6	-0.0
Severe depression (siblings)	0.1	0.1	0.7	-0.2	-0.1	0.0	-0.2	-0.1	-0.1	0.4	0.8	-0.9	0.4	-0.1	-0.2	-0.2
Impedance of leg (right)	0.1	0.4	2.0	-0.4	-0.5	-0.1	-0.8	-0.4	-0.7	0.3	0.6	-0.6	-0.1	-0.6	-1.4	-0.3
Average weekly fortified wine intake	0.1	0.1	0.8	0.1	0.3	-0.0	0.2	0.3	0.2	-0.0	0.3	0.9	-0.1	0.2	-0.1	0.2
Maternal smoking around birth	0.1	0.2	0.7	-0.8	0.1	-0.5	-0.6	0.1	-0.6	-0.1	0.1	-0.8	0.2	-0.2	-0.1	-0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.5	-0.3	0.1	0.3	0.0	0.1	0.3	0.5	0.7	-0.2	0.2	0.3	-0.5	0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.8	0.2	-0.1	0.1	0.3	-0.2	0.2	0.3	0.9	0.1	-0.3	-0.1	0.4	-0.2
Sitting height	0.1	0.4	1.6	-0.4	-0.4	-0.4	-0.8	-0.4	-0.9	-0.5	-0.8	-1.2	-0.0	-0.5	-0.2	-0.5
Leg predicted mass (left)	0.1	0.8	3.3	1.0	0.8	0.4	1.3	0.7	1.2	0.3	-0.3	0.4	0.5	0.9	1.8	0.5
Had menopause	0.1	0.1	0.9	0.3	0.1	0.3	-0.0	0.2	-0.1	-0.2	0.5	-0.9	0.3	0.1	0.2	0.1
Fluid intelligence score	0.1	0.2	0.6	0.4	0.5	0.6	0.2	0.5	-0.1	0.3	-0.1	-0.6	0.8	0.5	0.1	0.4
Impedance of arm (right)	0.1	0.7	4.4	0.5	0.9	0.6	0.3	0.9	0.3	0.5	2.1	-0.3	0.8	0.8	-0.1	0.6
Time employed in main current job	0.1	0.1	0.4	0.1	-0.1	0.4	-0.4	-0.0	-0.6	0.1	-0.6	0.0	0.1	-0.0	-0.4	0.1
Qualifications: A levels/AS levels or equivalent	0.1	0.1	0.8	0.4	0.1	0.3	0.0	0.1	-0.1	-0.0	-0.9	-0.7	-0.1	0.1	0.1	0.0
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.6	-0.0	0.1	0.3	0.4	0.1	0.4	0.5	0.3	0.8	0.1	0.3	0.4	0.2
Depression (self-reported)	0.1	0.1	0.4	-0.6	-0.1	-0.3	0.2	-0.2	0.2	0.0	0.5	0.1	-0.2	0.2	-0.6	-0.1
Impedance of arm (left)	0.1	0.4	2.8	0.3	0.6	0.3	0.2	0.7	0.1	0.4	1.7	-0.3	0.6	0.5	-0.3	0.4
Birth weight of first child	0.1	0.2	1.4	0.3	0.1	-0.1	-0.0	0.1	-0.4	-0.8	-1.2	-0.3	-0.0	0.1	0.2	-0.0
Headache pain in last month	0.1	0.2	0.9	-0.2	0.2	-0.3	0.3	0.1	0.3	-0.3	-0.0	1.0	0.0	0.1	0.9	0.1
Birth weight	0.1	0.2	0.5	0.5	0.3	0.6	0.5	0.3	0.3	0.3	-0.5	0.5	0.7	0.5	0.1	0.6
Arm fat-free mass (right)	0.1	0.4	1.3	0.8	0.1	0.3	0.9	0.2	0.9	0.2	-1.1	0.5	-0.0	0.4	1.1	0.2
Comparative body size at age 10	0.1	0.4	1.7	0.6	0.8	0.3	0.5	0.7	0.5	0.0	-0.4	0.2	0.7	0.5	1.3	0.6
Number of children fathered	0.1	0.2	0.7	0.0	0.3	0.3	-0.2	0.3	-0.3	-0.8	-0.3	0.6	0.2	0.4	-0.3	0.4
Arm predicted mass (right)	0.1	0.3	1.9	0.5	-0.2	0.1	0.6	-0.2	0.6	-0.0	-1.4	0.4	-0.3	0.0	0.7	-0.1
Age at last live birth	0.1	0.1	0.6	0.1	-0.2	-0.1	0.2	-0.2	0.2	-0.3	-0.3	0.1	-0.8	-0.0	-0.1	-0.2
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.4	-0.2	-0.2	0.3	-0.4	-0.2	-0.2	0.5	0.5	-0.6	0.3	-0.2	-0.1	-0.0
Knee pain experienced in last month	0.1	0.1	0.8	0.3	-0.3	0.0	0.1	-0.2	0.3	-0.1	0.9	-0.3	-0.3	-0.2	-0.2	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.5	0.1	0.2	0.2	0.0	0.2	-0.1	0.1	0.7	-0.4	0.2	0.1	0.6	0.2
Illnesses of father: Heart disease	0.1	0.1	0.8	-0.1	0.0	0.2	0.0	0.1	0.3	0.9	0.6	0.3	0.6	-0.1	-0.2	0.2
Whole body fat-free mass	0.1	0.4	1.3	0.7	0.2	0.3	0.9	0.2	0.9	0.2	-0.8	0.4	0.0	0.5	1.2	0.2
Breast cancer (self-reported)	0.1	0.1	0.7	-0.1	0.0	0.1	-0.2	0.1	-0.0	0.7	-0.5	0.0	0.8	-0.1	0.3	0.2
Whole body water mass	0.1	0.4	1.3	0.7	0.3	0.3	0.9	0.2	0.8	0.1	-0.9	0.3	0.0	0.5	1.2	0.2
Ever taken oral contraceptive pill	0.1	0.1	0.2	0.1	0.2	-0.1	0.4	0.3	0.3	0.3	-0.2	-0.2	0.4	0.4	-0.0	0.1
Hearing aid user	0.1	0.2	0.6	-0.2	-0.4	-0.5	-0.0	-0.4	-0.1	-0.6	-0.0	0.4	-0.8	-0.4	-0.1	-0.4
Tinnitus: Yes, now most or all of the time	0.1	0.2	1.1	-0.0	-0.1	-0.1	0.4	-0.2	0.4	-0.1	-0.0	1.0	-0.7	0.0	0.4	-0.0
Commuting to job workplace: Public transport	0.1	0.2	0.7	0.1	0.0	-0.6	-0.1	0.0	-0.4	-0.8	-0.5	-0.5	-0.5	-0.1	0.2	-0.3
Basal metabolic rate	0.1	0.8	2.6	1.1	0.7	0.6	1.4	0.7	1.3	0.4	-0.4	0.7	0.4	0.9	1.6	0.6
Arm fat-free mass (left)	0.1	0.5	1.9	0.9	0.4	0.4	1.1	0.4	1.0	0.3	-0.8	0.4	0.1	0.6	1.4	0.3
Risk taking	0.1	0.1	0.3	0.1	0.4	0.1	-0.2	0.3	-0.3	-0.1	-0.3	-0.5	0.4	0.1	0.5	0.3
Fractured/broken bones in last 5 years	0.1	0.2	0.7	0.4	-0.1	0.3	0.4	-0.0	0.7	-0.0	0.8	-0.1	-0.4	0.2	-0.6	0.0
Myopia	0.1	0.2	1.9	-0.0	-0.3	-0.1	-0.1	-0.3	-0.2	0.1	-1.4	-0.0	-0.1	-0.3	0.3	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	-0.1	-0.2	-0.2	0.1	-0.2	-0.1	-0.3	-0.5	-0.2	-0.5	-0.1	-0.3	-0.3
Impedance of whole body	0.1	0.3	1.8	0.3	0.4	0.5	0.1	0.5	0.2	0.7	1.3	-0.3	0.6	0.4	-0.6	0.4
Arm predicted mass (left)	0.1	0.3	1.2	0.5	0.1	0.1	0.8	0.1	0.7	-0.0	-1.0	0.2	-0.2	0.3	1.1	0.1
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Height	0.0	0.9	2.9	-0.2	-1.4	-0.3	-0.3	-1.3	-0.3	-0.7	-0.6	0.4	-1.7	-0.9	-1.7	-0.9
Hair Pigment	0.0	0.1	0.7	0.1	-0.2	-0.3	0.5	-0.2	0.4	0.0	-0.1	0.8	-0.4	0.1	-0.3	-0.2
Tanning	0.0	0.1	0.5	-0.3	-0.2	-0.0	-0.4	-0.2	-0.2	0.5	-0.7	0.4	0.3	-0.2	-0.3	-0.1
Impedance of leg (left)	0.0	0.2	1.6	0.0	-0.3	0.3	-0.3	-0.2	-0.2	0.7	0.6	-0.1	0.0	-0.3	-1.3	-0.0
Trunk fat-free mass	0.0	0.2	0.8	0.6	0.0	0.3	0.7	0.0	0.7	0.2	-0.9	0.4	-0.1	0.3	0.7	0.2
Trunk predicted mass	0.0	0.3	0.7	0.6	0.1	0.4	0.8	0.1	0.7	0.4	-0.8	0.5	0.0	0.4	0.8	0.3
Standing height	0.0	0.2	1.2	-0.1	-0.7	-0.1	-0.3	-0.5	-0.3	0.0	-0.5	-0.6	-0.5	-0.3	-1.1	-0.4
Blood clot in the leg (DVT)	0.0	0.1	0.2	-0.2	-0.2	-0.3	0.1	-0.1	-0.0	-0.2	-0.3	-0.1	-0.4	-0.1	-0.4	-0.3
Comparative height size at age 10	0.0	0.2	0.8	0.9	0.2	0.5	0.8	0.3	0.3	0.0	-0.6	0.4	-0.1	0.6	-0.2	0.3
Number of operations (self-reported)	0.0	0.1	0.3	0.3	-0.1	0.0	0.3	-0.1	0.1	0.2	-0.1	0.4	-0.1	-0.1	0.6	-0.2
Commuting to job workplace: Cycle	0.0	0.0	0.1	-0.3	-0.1	-0.4	-0.2	-0.1	-0.0	-0.3	0.1	-0.2	-0.3	-0.3	-0.2	-0.2

Hub : Genes

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