TWAS hub - LOC652276

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0850	0.0410	1.8e-05	0.032	0.055	0.041	NA	0.045	9.4e-04	1.9e-05	2.2e-04	NA	1.1e-04
2	TCGA	Breast Invasive Carcinoma	0.0226	0.0124	1.2e-03	-0.001	0.008	0.008	NA	0.000	8.9e-01	7.9e-03	7.3e-03	NA	2.5e-01
3	TCGA	Cervical Squamous Cell Carcinoma	0.1040	0.0550	3.2e-03	0.017	0.041	0.016	NA	0.020	4.6e-02	4.2e-03	5.1e-02	NA	3.6e-02
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0481	0.0268	1.4e-03	0.011	0.022	0.002	NA	0.022	1.6e-02	1.3e-03	1.7e-01	NA	1.6e-03
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2100	0.0860	4.0e-06	0.078	0.074	0.021	NA	0.085	2.9e-05	4.7e-05	2.2e-02	NA	1.3e-05
6	TCGA	Brain Lower Grade Glioma	0.0710	0.0309	1.9e-10	0.087	0.093	0.083	NA	0.083	3.8e-10	9.6e-11	1.0e-09	NA	1.2e-09
7	TCGA	Lung Adenocarcinoma	0.0180	0.0114	5.6e-03	0.021	0.012	0.000	NA	0.014	1.3e-03	1.3e-02	3.6e-01	NA	7.0e-03
8	TCGA	Pancreatic Adenocarcinoma	0.1270	0.0680	2.3e-03	0.004	0.053	0.038	NA	0.029	2.1e-01	2.9e-03	1.0e-02	NA	2.3e-02
9	TCGA	Pheochromocytoma and Paraganglioma	0.2660	0.0940	1.7e-08	0.034	0.150	0.157	NA	0.139	1.6e-02	1.5e-06	8.5e-07	NA	3.7e-06
10	TCGA	Prostate Adenocarcinoma	0.1204	0.0586	3.5e-08	0.053	0.074	0.108	NA	0.074	2.8e-06	3.2e-08	2.5e-11	NA	3.8e-08
11	TCGA	Thyroid Carcinoma	0.0850	0.0410	1.2e-04	0.017	0.048	0.052	NA	0.051	7.8e-03	1.6e-05	7.4e-06	NA	1.1e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Had major operations	5.0	5.9	12.2	2.2	3.0	1.0	2.5	0.1	3.2	1.8	1.6	3.3	3.5	2.0
Exposure to tobacco smoke outside home	4.7	6.2	10.0	-3.0	-2.8	-1.4	-2.8	-0.4	-3.0	-3.2	-2.8	-2.6	-2.7	-1.2
Medication: Simvastatin	3.6	5.2	10.3	2.2	2.0	1.4	2.4	1.0	2.8	1.8	1.9	2.8	3.2	2.5
Qualifications: NVQ or HND or HNC or equivalent	3.2	3.8	6.7	-2.1	-2.1	-0.7	-2.2	-0.7	-2.5	-2.6	-2.1	-1.9	-1.9	-1.5
Ever depressed for a whole week	3.0	3.6	5.6	2.0	1.7	1.8	2.3	1.2	2.0	1.5	1.8	2.4	1.4	2.3
Stomach or abdominal pain in last month	2.3	2.8	5.3	-2.1	-1.7	-0.9	-1.7	-1.1	-1.9	-2.1	-2.3	-1.2	-1.6	-1.2
Illnesses of siblings: Diabetes	2.2	2.7	7.3	-2.1	-1.7	-0.7	-1.7	0.9	-1.8	-2.7	-2.0	-1.5	-0.6	0.7
Medication: Levothyroxine sodium	2.1	3.5	14.5	-1.7	-1.3	1.0	-1.0	1.6	-2.6	-3.8	-2.0	-1.4	-1.1	1.2
Diabetes (mother)	2.0	2.5	5.6	-2.3	-1.3	-1.2	-1.7	-0.3	-1.7	-2.3	-2.4	-1.4	-0.6	-0.3
Nervous feelings	2.0	3.7	8.1	-2.4	-1.0	-2.3	-2.5	-0.1	-2.0	-2.0	-2.1	-2.8	-0.2	-1.5
Mouth/teeth dental problems: Bleeding gums	2.0	2.6	6.8	-1.5	-0.7	0.4	-1.0	1.6	-2.5	-2.6	-1.3	-2.1	-1.7	0.4
Alzheimer’s Disease (in mother)	1.9	2.3	5.6	-2.1	-2.0	-0.4	-1.2	-0.8	-1.5	-2.0	-2.4	-0.3	-1.5	0.1
Medication: Gliclazide	1.9	2.1	4.2	-1.6	-1.5	-0.6	-1.5	-0.8	-1.8	-1.5	-1.6	-1.3	-2.1	-1.3
Leg pain on walking	1.8	2.2	4.8	1.6	1.0	0.5	1.5	-0.4	2.2	2.2	1.4	2.1	1.2	0.8
Worry (Nagel 2018)	1.7	3.5	11.0	-2.2	-0.5	-2.3	-2.4	0.0	-2.0	-1.8	-1.7	-3.3	-0.4	-1.2
Medication: Atenolol	1.7	2.2	6.6	1.3	1.5	2.6	2.0	1.3	0.4	-0.1	0.9	1.6	0.3	1.9
Sitting height	1.7	11.9	24.2	4.3	2.5	3.9	4.0	0.9	3.8	2.5	3.5	4.9	2.5	3.1
Mouth/teeth dental problems: Loose teeth	1.7	2.0	6.2	0.6	0.7	2.5	1.4	2.0	-0.3	-1.2	0.4	1.0	-0.3	2.5
Chest pain or discomfort	1.7	2.4	4.6	-2.1	-1.3	-1.3	-1.8	-0.3	-1.7	-2.1	-2.1	-1.7	-0.8	-0.7
Back pain experienced in last month	1.7	2.5	7.1	0.9	-0.5	-1.6	-0.2	-2.1	2.7	2.3	0.8	1.7	1.7	-0.6
HbA1C	1.6	1.8	5.2	-1.4	0.0	-1.6	-1.8	0.0	-1.2	-0.4	-1.3	0.0	-1.9	-2.3
Age when periods started (menarche)	1.6	3.8	10.1	-1.3	-2.3	-2.0	-1.8	-2.7	-1.0	0.7	-1.0	-1.3	-2.4	-3.2
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	3.2	1.8	1.1	1.2	1.6	0.6	1.4	1.5	1.8	1.4	0.5	0.9
Heart disease (siblings)	1.6	2.0	7.9	-1.7	-0.3	0.5	-0.6	0.9	-2.1	-2.8	-1.9	-1.1	-0.5	0.6
Crohns Disease (2017)	1.5	3.3	7.1	1.5	2.2	1.5	2.2	0.3	2.0	1.2	1.0	2.7	2.3	1.8
Ulcerative Colitis (UC)	1.5	2.8	6.6	-2.2	-0.8	-2.5	-1.9	-2.2	-0.4	-1.2	-2.6	-0.5	0.7	-1.4
Severe depression (siblings)	1.5	1.6	4.0	-1.5	-1.2	-0.3	-1.3	-0.5	-1.6	-2.0	-1.7	-0.9	-1.1	-0.7
Chronic bronchitis/emphysema (father)	1.5	1.7	4.3	-1.3	-1.8	-2.1	-1.7	-1.8	0.0	-0.1	-1.3	-0.4	0.4	-1.3
Illnesses of father: High blood pressure	1.5	1.9	3.3	1.6	0.8	1.5	1.6	1.1	1.4	0.9	1.4	1.6	0.9	1.8
Average weekly spirits intake	1.4	1.7	6.0	1.1	1.4	-0.6	0.6	-0.5	1.6	1.9	1.2	0.7	2.4	-0.5
Medication: Cholesterol lowering	1.4	2.2	5.5	1.2	1.0	0.5	1.7	-0.2	2.1	1.7	1.0	2.3	1.6	1.6
Loud music exposure frequency	1.4	1.5	5.7	1.3	-0.0	-0.0	0.7	-1.4	1.5	2.4	1.4	1.2	0.2	-1.0
Medication for cholesterol, blood pressure or diabetes	1.4	2.3	3.9	-1.5	-1.1	-1.0	-1.9	-0.7	-1.9	-1.5	-1.3	-2.0	-1.6	-1.9
Glaucoma (self-reported)	1.4	1.6	3.7	1.7	1.7	0.5	1.3	0.5	1.3	1.9	1.9	0.6	0.9	0.1
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	9.0	-0.7	-0.1	1.7	-0.1	2.6	-2.1	-3.0	-0.7	-1.3	-0.6	1.7
Wheeze or whistling in the chest in last year	1.4	2.5	6.2	-1.5	-1.9	-2.1	-1.9	-2.5	-0.3	-0.6	-1.7	-0.3	-0.4	-1.9
Suffer from ‘nerves’	1.4	2.2	5.2	-2.1	-0.9	-2.3	-1.9	-0.5	-1.1	-1.1	-1.8	-1.8	-0.6	-0.9
Mood swings	1.4	2.5	4.7	-2.2	-1.1	-1.8	-1.9	-0.2	-1.7	-1.6	-1.9	-2.1	-1.0	-0.9
Intelligence (Savage-Jansen 2018)	1.3	3.9	11.9	1.9	-0.0	-0.9	0.9	0.0	3.4	3.5	1.9	2.3	2.2	0.2
Height	1.3	25.1	67.1	6.8	2.7	8.2	6.0	3.7	3.1	2.3	6.2	5.4	0.9	4.8
Prospective memory result	1.3	1.6	5.3	1.2	0.7	1.9	1.3	2.3	-0.1	0.4	1.6	0.1	-0.2	1.6
Standing height	1.3	12.7	31.0	4.6	2.3	5.6	4.1	3.3	2.2	1.4	4.3	3.6	0.7	4.0
Mean time to correctly identify matches	1.3	2.4	7.6	1.8	1.1	2.8	2.2	1.1	0.6	0.8	1.6	1.7	0.7	1.5
Medication: Atorvastatin	1.3	1.7	2.9	-1.6	-0.9	-1.4	-1.2	-1.4	-1.1	-0.7	-1.7	-0.9	-1.5	-1.4
Supplements: Calcium	1.3	1.5	4.0	0.2	-0.8	-2.0	-1.0	-1.4	0.7	1.7	0.6	-0.7	-0.5	-2.0
Average weekly fortified wine intake	1.2	1.4	4.3	1.4	2.1	1.1	1.2	0.1	1.1	0.7	1.0	1.2	1.5	0.2
Father’s age at death	1.2	1.6	2.8	1.4	0.6	0.5	1.1	1.1	1.6	1.6	1.7	1.0	1.4	1.4
Pulse rate	1.2	2.1	8.4	1.0	1.9	-0.9	0.6	0.5	2.1	1.3	1.1	0.8	2.9	0.8
Commuting to job workplace: Public transport	1.2	1.4	4.0	0.8	1.7	2.0	1.3	1.6	-0.2	-0.7	0.6	0.5	0.9	1.3
Heart attack	1.1	1.3	3.7	0.7	0.8	0.4	1.1	-0.0	1.6	0.7	0.4	1.9	1.7	1.5
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	4.2	-0.8	-0.9	-2.0	-1.3	-1.7	0.3	0.8	-0.6	-0.5	-0.1	-1.6
Medication: Bendroflumethiazide	1.1	1.7	3.1	-1.3	-1.0	-0.5	-1.4	-1.5	-1.4	-1.7	-1.6	-0.8	-0.8	-1.7
Alcohol drinker status: Never	1.1	1.3	2.5	-1.4	0.1	-1.4	-1.3	-0.3	-1.1	-1.3	-1.3	-1.6	0.3	-1.1
Alzheimer’s Disease (in father)	1.0	1.1	2.7	1.6	1.0	1.0	1.0	0.5	1.0	1.1	1.6	0.8	0.5	0.3
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	5.9	0.7	1.7	0.5	1.0	0.2	1.1	0.1	0.3	1.3	2.4	1.0
Fed-up feelings	1.0	1.7	6.3	-1.5	-0.5	-2.5	-1.7	-0.9	-0.5	0.0	-1.1	-1.6	-0.0	-1.6
Financial difficulties in last 2 years	1.0	1.3	4.6	-1.5	-0.1	-0.4	-1.0	0.4	-1.4	-2.1	-1.6	-1.0	-0.7	0.2
Length of working week for main job	1.0	1.1	2.3	0.6	1.5	1.4	1.1	0.6	0.6	-0.2	0.2	1.4	1.2	1.3
Tense / ‘highly strung’	1.0	1.7	8.1	-1.7	-0.3	-2.9	-1.6	0.2	-0.2	-0.2	-1.2	-1.7	0.4	-0.2
Arm fat-free mass (right)	1.0	5.2	14.1	1.8	1.2	2.6	2.4	1.1	2.3	0.1	1.0	3.8	2.1	3.7
Comparative height size at age 10	1.0	5.5	10.2	3.1	1.3	3.2	2.5	2.1	1.9	1.1	2.9	2.4	1.7	2.6
Knee pain experienced in last month	1.0	1.5	7.3	-0.8	-1.3	-1.4	-0.8	-2.7	0.5	0.6	-1.1	0.7	-0.3	-1.5
Average weekly red wine intake	1.0	1.5	4.1	1.9	1.1	1.1	1.2	0.2	0.8	1.9	2.0	0.5	-0.4	-0.5
Eye problems/disorders: Cataract	1.0	1.2	2.9	1.5	1.7	1.3	1.2	0.8	0.3	1.1	1.6	0.1	0.6	-0.2
Medication: Blood pressure	1.0	1.9	4.8	1.4	1.8	2.2	1.6	1.5	0.5	-0.1	1.2	1.1	1.3	1.5
Neuroticism (Nagel 2018)	0.9	2.0	7.2	-1.6	-0.4	-1.6	-1.8	0.0	-1.7	-1.2	-1.0	-2.7	-0.6	-1.0
Fasting Glucose	0.9	1.1	1.7	-1.3	-0.9	-1.1	-1.3	0.0	-1.1	-0.9	-1.2	-1.2	-0.7	-1.1
Systolic Blood Pressure	0.9	4.3	9.5	1.6	1.3	0.7	2.3	0.3	2.9	2.0	1.3	3.1	2.6	2.6
Alcohol usually taken with meals	0.9	1.5	3.7	1.4	1.2	1.5	1.2	1.9	0.5	0.2	1.5	0.4	0.6	1.5
Hearing difficulty/problems with background noise	0.9	1.4	5.9	0.4	-0.7	-1.4	0.1	-1.6	1.7	2.4	0.6	0.9	0.2	-0.7
Trunk fat-free mass	0.9	5.2	13.2	2.4	1.6	3.0	2.6	0.9	2.2	0.4	1.6	3.6	1.6	3.0
Trunk predicted mass	0.9	5.3	13.2	2.4	1.6	3.1	2.6	1.0	2.2	0.4	1.6	3.6	1.6	3.1
Chronic bronchitis/emphysema (mother)	0.9	1.1	5.0	0.3	-0.2	-0.9	-0.1	-2.2	1.1	1.4	0.1	1.0	0.1	-1.4
Heart disease (mother)	0.9	1.0	2.6	0.4	1.6	1.2	0.9	1.6	-0.2	-0.9	0.2	0.1	1.1	1.4
Arm predicted mass (right)	0.9	4.4	13.6	1.6	1.0	2.5	2.2	0.8	2.1	-0.1	0.8	3.7	1.8	3.4
Medication for cholesterol	0.9	1.3	3.3	-1.1	-1.0	-0.9	-1.0	-1.2	-1.0	-0.5	-1.0	-1.0	-1.8	-1.5
Ever taken oral contraceptive pill	0.9	1.0	2.9	-1.2	-0.8	-0.9	-0.8	-1.7	-0.6	-0.6	-1.5	-0.1	-0.8	-1.2
Heart attack/myocardial infarction (self-reported)	0.9	1.2	3.1	0.7	0.8	0.3	1.0	-0.0	1.5	0.7	0.4	1.7	1.7	1.4
Verbal and Numeric Reasoning (VNR)	0.8	1.8	5.3	1.6	0.3	-0.3	0.6	-0.6	2.3	2.1	1.6	1.6	1.3	0.1
Heel T-Score	0.8	6.1	16.3	-2.5	-2.6	-4.0	-3.0	-3.2	-0.5	0.0	-2.3	-1.6	-1.4	-3.0
Hypothyroidism (self reported)	0.8	1.9	5.7	-0.2	0.3	2.0	0.5	2.4	-1.5	-2.2	-0.3	-0.5	-0.3	1.9
Time employed in main current job	0.8	0.9	4.1	0.5	1.3	0.7	0.5	2.0	0.2	-0.3	0.7	-0.2	0.8	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	3.9	0.5	1.3	1.2	1.0	1.4	0.5	-0.9	0.2	1.0	1.2	2.0
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	2.1	-1.2	-1.2	-1.0	-1.3	-1.4	-0.7	-1.0	-1.4	-0.4	-0.6	-1.2
Eye problems/disorders: None of the above	0.8	1.0	2.7	-1.3	-1.6	-1.5	-1.2	-0.7	-0.2	-0.5	-1.2	-0.4	-0.3	-0.1
Medication: Allopurinol	0.8	1.1	2.5	-1.4	-0.5	-1.5	-1.2	-0.6	0.2	-1.2	-1.6	-0.0	1.6	0.3
Whole body fat-free mass	0.8	4.4	12.8	2.0	1.3	2.7	2.4	0.6	2.1	0.3	1.1	3.6	1.5	2.9
Whole body water mass	0.8	4.4	12.6	2.0	1.2	2.8	2.4	0.7	2.0	0.2	1.2	3.5	1.4	3.0
Tinnitus: Yes, now most or all of the time	0.8	0.9	1.7	1.1	1.3	0.5	0.8	0.3	1.3	0.7	0.9	1.1	1.1	0.7
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.9	0.7	-0.3	0.1	0.7	-1.3	1.6	1.2	0.4	2.0	0.2	0.3
Number of operations (self-reported)	0.8	1.1	3.4	0.4	0.1	-1.3	-0.1	-1.3	1.9	1.3	0.3	1.1	1.6	-0.3
Unable to work because of sickness or disability	0.8	1.1	2.6	1.0	0.9	-0.1	1.0	-0.3	1.6	1.6	1.0	1.2	1.2	0.4
Myopia	0.8	1.1	4.2	-1.0	1.0	0.2	-0.3	1.2	-1.3	-2.0	-1.1	-1.0	0.5	0.6
Pain experienced in last month	0.8	1.4	3.9	-0.1	0.4	1.4	0.2	1.8	-2.0	-1.3	0.2	-1.7	-1.1	0.0
Reaction Time	0.7	1.4	3.7	1.4	1.0	1.9	1.7	0.6	0.6	0.8	1.2	1.3	0.8	0.9
Blood Eosinophil Count	0.7	5.6	11.4	2.4	3.2	0.4	2.0	0.5	3.4	2.2	2.2	2.5	3.3	1.5
Neuroticism	0.7	1.6	3.8	-1.6	-0.5	-1.3	-1.6	0.9	-1.2	-1.7	-1.3	-1.9	0.2	0.0
Sensitivity / hurt feelings	0.7	1.2	2.9	-1.0	-1.7	-0.1	-1.1	-0.2	-1.3	-1.4	-1.0	-0.8	-1.4	-0.4
Leg fat-free mass (left)	0.7	3.7	12.3	1.7	0.9	2.4	2.3	0.2	2.0	0.5	1.0	3.5	1.3	2.6
Maternal smoking around birth	0.7	1.1	3.4	1.0	1.8	0.6	1.1	-0.6	1.2	0.9	0.6	1.5	0.7	-0.0
Supplements: Glucosamine	0.7	0.9	3.3	-0.6	-1.8	-1.5	-1.5	-0.4	0.1	0.2	-0.2	-0.8	-0.3	-0.6
Leg predicted mass (left)	0.7	3.5	12.0	1.6	0.9	2.4	2.2	0.1	1.9	0.4	0.8	3.5	1.2	2.5
Had other major operations	0.7	0.9	3.1	-0.8	-1.7	-1.3	-1.3	-0.5	-0.4	-0.3	-0.6	-0.9	-0.6	-0.7
Allergy	0.7	1.7	3.5	1.4	1.4	1.9	1.8	1.1	0.7	0.7	1.3	1.3	0.7	1.4
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.9	0.9	1.1	1.7	0.8	1.4	-0.6	-0.4	1.0	-0.3	-0.6	0.4
Hip circumference	0.7	3.0	8.3	1.8	1.0	2.1	2.1	0.3	1.8	1.0	1.2	2.9	1.2	2.0
Birth weight of first child	0.7	1.3	3.1	-0.5	-1.1	0.5	-0.9	1.4	-1.5	-1.5	-0.1	-1.5	-1.8	0.2
Age at first live birth	0.7	1.2	2.9	-0.7	-1.1	-1.0	-1.1	-0.6	-1.1	-0.2	-0.4	-1.6	-1.5	-1.7
Medication for pain relief, constipation, heartburn	0.7	1.1	3.8	1.1	0.8	1.9	1.1	1.1	-0.8	0.4	1.3	-0.4	-1.4	-0.2
Smoking status: Previous	0.7	1.0	1.9	1.4	0.8	0.8	1.0	0.5	1.2	1.1	1.4	1.0	0.4	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	2.6	1.5	0.3	0.9	1.1	0.6	1.5	1.5	1.6	1.4	0.9	1.1
Medication: Aspirin	0.7	0.9	2.7	-0.8	-0.8	-1.6	-1.1	-1.6	0.3	-0.0	-1.0	-0.1	0.4	-1.1
Miserableness	0.7	1.3	4.6	-1.4	-0.1	-1.1	-1.1	1.1	-1.4	-1.0	-0.8	-2.1	-0.5	-0.1
Wears glasses or contact lenses	0.7	0.8	2.8	0.6	1.7	1.0	1.2	0.6	0.5	0.3	0.5	0.8	0.6	0.9
Eye problems/disorders: Glaucoma	0.7	0.8	3.8	1.0	0.9	-0.4	0.6	-0.2	1.0	1.9	1.2	0.2	0.1	-0.5
Arm fat-free mass (left)	0.7	3.7	11.8	1.5	0.8	2.3	2.0	0.5	2.0	-0.1	0.7	3.4	1.6	3.0
Risk taking	0.7	1.1	3.6	0.9	0.3	-0.0	1.1	-1.1	1.4	1.9	0.8	1.5	0.3	-0.1
Arm predicted mass (left)	0.7	3.7	11.5	1.4	0.8	2.5	2.0	0.7	1.8	-0.4	0.6	3.4	1.5	3.2
Depressed Affect (Nagel 2018)	0.6	1.2	4.5	-1.1	-0.3	-1.6	-1.5	0.0	-0.9	-0.4	-0.6	-2.1	-0.3	-0.9
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	2.9	0.7	1.7	0.4	1.0	0.3	0.7	0.9	0.7	0.5	0.4	0.3
Pack years adult smoking proportion	0.6	0.9	2.4	-1.0	-0.0	-0.9	-0.3	-1.1	0.8	-0.9	-1.6	1.2	1.0	0.7
Number of incorrect matches in round	0.6	0.9	2.6	-1.0	-0.2	0.0	-0.7	0.5	-1.6	-1.4	-0.9	-1.4	-1.0	-0.4
Pain all over the body in last month	0.6	0.6	2.2	-0.2	0.1	-1.5	-0.3	-1.2	1.0	1.1	-0.2	0.3	0.6	-0.7
Pulse wave Arterial Stiffness index	0.6	0.7	2.1	0.8	0.4	0.2	0.9	-0.8	1.1	1.5	0.7	1.2	0.3	-0.1
Medication: Paracetamol	0.6	0.9	3.8	0.3	-0.8	0.1	0.3	-0.3	1.5	0.1	-0.0	1.9	0.8	1.6
Number of children fathered	0.6	0.6	1.2	0.0	-0.9	-1.0	-0.8	-0.2	-0.1	1.0	0.5	-1.1	-1.0	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.4	-1.0	-0.6	-0.7	-1.0	-0.1	-1.0	-0.8	-0.8	-1.2	-1.1	-0.7
Loneliness, isolation	0.6	0.8	1.7	0.8	0.8	0.3	0.6	1.1	1.0	0.4	0.9	0.5	1.3	1.3
Breast cancer (self-reported)	0.6	0.7	3.2	-0.7	-0.2	0.2	-0.6	0.6	-1.1	-1.8	-0.8	-0.9	-0.2	0.1
Average weekly champagne plus white wine intake	0.6	0.9	2.3	-0.8	-1.5	-0.6	-1.3	-0.1	-0.8	-1.3	-0.7	-0.9	-0.7	-0.4
Basal metabolic rate	0.6	3.5	11.5	1.6	0.9	2.5	2.1	0.4	1.8	0.1	0.8	3.4	1.3	2.7
Fractured/broken bones in last 5 years	0.6	0.8	2.0	0.8	0.9	1.3	1.0	1.4	0.3	-0.1	0.8	0.5	0.4	1.4
Age at First Birth	0.5	0.8	3.0	-1.0	0.4	-0.7	-0.9	0.0	-1.2	-1.1	-0.7	-1.7	0.2	-0.1
Lupus	0.5	0.7	2.0	-0.3	-1.1	-1.4	-0.6	0.0	0.7	1.2	-0.3	0.4	-0.1	-1.4
Number of treatments/medications taken	0.5	0.9	2.7	0.4	0.4	0.2	0.8	0.5	1.2	0.4	0.3	1.3	1.6	1.6
Ever had hysterectomy (womb removed)	0.5	0.5	1.2	0.8	0.1	0.7	0.5	0.9	0.7	0.1	0.8	0.6	1.1	1.1
Angina	0.5	0.7	1.5	-1.0	-0.0	-0.5	-0.6	0.2	-1.1	-1.2	-1.0	-1.1	-0.9	-0.2
Medication for hormone replacement therapy	0.5	0.6	2.5	0.3	-0.5	0.1	0.6	-0.7	1.1	0.6	-0.0	1.6	0.7	0.9
Supplements: Zinc	0.5	0.5	2.1	0.2	-1.5	-0.4	-0.2	-1.0	0.3	0.9	0.3	0.2	-0.9	-0.6
Qualifications: CSEs or equivalent	0.5	0.7	2.6	-0.4	-0.2	1.3	0.3	0.5	-1.4	-0.9	-0.4	-0.4	-1.6	0.0
Waist circumference	0.5	2.0	6.7	0.7	0.4	1.8	1.5	0.4	1.2	-0.3	0.1	2.6	1.1	2.5
Past tobacco smoking	0.5	0.9	2.1	-1.2	-0.5	-0.8	-1.0	0.3	-1.2	-1.1	-1.0	-1.4	-0.4	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	3.8	-1.1	0.3	-2.0	-1.0	-0.2	0.1	-0.3	-0.9	-0.9	0.2	-0.3
Had menopause	0.5	0.6	2.8	0.3	-0.2	0.7	0.3	1.4	0.3	-0.5	0.4	0.3	0.4	1.7
Forced vital capacity (FVC)	0.5	1.9	6.3	1.6	1.6	2.5	1.7	1.5	0.1	-0.0	1.4	0.9	0.1	1.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	3.7	-0.0	-0.0	0.7	0.4	1.0	0.3	-0.9	-0.3	0.9	0.1	1.9
Illnesses of siblings	0.5	0.7	2.0	1.2	0.4	0.2	0.3	-0.4	0.7	1.4	1.4	0.1	-0.2	-1.0
Neuroticism score	0.5	1.0	2.4	-1.5	-0.2	-1.6	-1.2	0.2	-0.7	-0.9	-1.2	-1.4	0.2	-0.2
Weight	0.5	2.3	8.6	1.0	0.2	2.0	1.6	0.2	1.4	-0.2	0.3	2.9	0.9	2.5
Worrier / anxious feelings	0.5	0.9	2.1	-1.2	-0.4	-1.3	-1.2	0.2	-0.8	-0.9	-0.9	-1.5	0.1	-0.4
Falls in the last year	0.5	0.7	2.7	-0.2	0.8	0.5	0.3	1.7	-0.3	-1.0	-0.2	-0.3	0.9	1.5
Number of live births	0.5	0.8	2.7	-0.4	-0.7	-1.6	-0.4	-1.4	0.8	1.4	-0.3	0.2	-0.2	-0.7
Mouth/teeth dental problems: Dentures	0.5	0.8	1.3	-1.1	-0.7	-1.1	-0.8	-1.1	-0.4	0.0	-1.0	-0.4	-1.1	-0.9
Depression (self-reported)	0.5	0.6	1.6	-0.6	-0.5	0.6	-0.3	0.4	-1.2	-1.1	-0.6	-0.5	-1.3	0.1
Medication: Lansoprazole	0.5	0.6	1.1	-0.8	-1.0	-0.6	-0.9	-0.9	-0.6	-0.5	-0.8	-0.5	-0.8	-0.9
Blood clot in the leg (DVT)	0.5	0.7	3.3	-0.4	-0.5	-1.8	-1.0	-0.7	0.5	0.9	-0.0	-0.7	-0.3	-1.0
Number of full brothers	0.5	0.7	1.7	-0.7	0.5	0.1	-0.1	1.3	-1.0	-1.2	-0.6	-1.0	-0.6	0.7
Pulse wave peak to peak time	0.5	0.6	1.9	-0.4	-0.2	0.4	-0.5	1.2	-1.0	-1.4	-0.3	-1.0	-0.4	0.4
Shortness of breath walking on level ground	0.5	0.5	1.6	-0.2	-0.3	-0.8	-0.1	-0.9	1.1	0.2	-0.5	1.1	1.3	0.4
Qualifications: College or University degree	0.5	1.6	6.9	-0.0	-1.2	-1.3	-0.7	-2.6	0.8	1.3	-0.2	0.5	-0.0	-2.0
Medication: Blood pressure	0.5	0.8	2.0	0.7	0.3	0.0	0.9	0.1	1.4	0.9	0.6	1.2	1.2	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.8	-0.2	0.2	0.3	-0.3	1.2	-1.2	-0.9	-0.0	-1.3	-1.1	-0.0
Age at last live birth	0.5	0.7	3.1	0.1	-0.5	0.0	-0.3	-0.0	-1.0	0.4	0.4	-1.3	-1.7	-1.3
Leg fat-free mass (right)	0.5	2.7	9.2	1.4	0.7	2.1	1.9	0.2	1.7	0.2	0.7	3.0	1.0	2.4
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.2	0.7	0.5	-0.1	0.4	-0.4	0.0	1.5	0.9	-0.5	-0.9	-1.3
Ever had bowel cancer screening	0.5	0.6	2.3	-0.5	-0.8	0.3	-0.7	0.7	-0.9	-1.5	-0.5	-0.7	-0.8	0.4
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	2.4	0.8	-0.2	-0.4	0.4	-0.4	1.5	1.5	0.9	1.1	0.6	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	3.8	-0.2	1.2	1.0	0.2	2.0	-1.0	-1.5	-0.1	-0.9	0.2	1.0
Leg predicted mass (right)	0.5	2.6	9.1	1.4	0.8	2.0	1.9	0.2	1.7	0.3	0.7	3.0	1.1	2.3
Guilty feelings	0.5	0.8	2.3	0.9	0.7	-0.1	0.9	-0.2	1.3	1.5	0.9	0.9	1.1	0.3
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.8	0.6	1.4	0.2	0.3	1.7	0.2	-0.0	0.8	-0.6	0.9	0.8
High cholesterol (Self-reported)	0.5	0.9	2.4	0.6	0.7	0.0	0.9	-0.0	1.3	1.1	0.5	1.2	1.5	0.9
Medication: Lisinopril	0.5	0.7	1.6	0.8	0.8	-0.1	0.6	0.2	1.1	1.2	0.9	0.6	1.2	0.3
Age started oral contraceptive pill	0.5	0.6	3.0	0.4	0.2	0.8	0.8	1.0	0.6	-0.1	0.3	0.9	0.5	1.7
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	2.9	-0.2	-0.5	-1.7	-1.0	-0.5	0.4	0.9	0.2	-0.8	-0.4	-1.0
Pack years of smoking	0.5	0.8	2.0	-0.7	0.3	-0.5	0.1	-0.6	0.9	-0.8	-1.2	1.4	1.0	1.2
Irritable Bowel Disease (IBD)	0.4	1.0	2.8	-0.9	0.7	-0.9	-0.2	-1.5	0.6	-0.3	-1.4	1.0	1.7	-0.2
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.5	-1.2	-0.3	-1.2	-1.0	-1.1	-0.6	-0.3	-1.2	-0.6	-0.2	-1.1
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.3	-0.3	-1.2	-1.0	-0.7	-0.5	0.8	-0.1	-0.4	0.4	1.1	0.4
Systolic blood pressure, automated reading	0.4	1.2	4.2	0.5	0.4	0.7	1.1	0.6	1.2	0.1	0.2	1.7	1.5	2.1
Medication: Metformin	0.4	0.5	1.4	-1.0	-0.7	-0.7	-0.8	-1.0	-0.4	-0.7	-1.2	-0.0	-0.2	-0.5
Taking other prescription medications	0.4	0.7	2.8	0.0	0.5	-0.1	0.5	0.6	0.9	-0.0	-0.1	0.8	1.7	1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	2.3	-1.4	-0.9	-1.4	-1.3	-0.7	-0.3	-1.1	-1.5	-0.5	-0.1	-0.2
Serious illness, injury or assault to yourself	0.4	0.5	1.6	0.3	0.1	0.4	0.6	0.2	0.8	-0.2	0.0	1.2	1.1	1.3
Diabetes (self-reported)	0.4	0.6	2.0	-0.7	-0.4	-1.4	-0.5	-1.2	0.7	0.5	-0.7	0.4	0.6	-0.2
Medication: Ramipril	0.4	0.5	2.0	-0.4	-0.9	-0.7	-0.2	-1.4	0.1	0.7	-0.5	0.3	-0.2	-0.8
Alcohol intake versus 10 years previously	0.4	0.7	1.1	-1.0	-1.0	-0.5	-0.9	-0.8	-0.8	-0.8	-1.1	-0.5	-0.7	-0.7
Hair/balding pattern: Pattern 3	0.4	0.5	2.0	0.4	0.8	1.1	0.6	1.4	-0.5	-0.2	0.6	-0.5	-0.6	0.6
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	5.5	1.1	1.2	2.3	1.2	1.5	-0.5	-0.5	0.9	0.3	-0.5	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.6	1.9	-0.8	-1.1	-1.4	-1.0	-0.7	0.2	-0.2	-0.8	-0.2	0.3	-0.2
Lung cancer (father)	0.4	0.4	1.2	-0.5	-0.4	-0.0	-0.6	0.4	-1.1	-0.7	-0.4	-1.1	-0.8	-0.4
Breastfed as a baby	0.4	0.5	1.3	1.0	0.0	0.4	0.6	0.3	0.7	1.1	1.1	0.5	-0.5	0.3
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.2	0.1	-0.7	-0.5	-0.2	-1.5	0.6	0.9	0.0	0.7	-0.5	-0.9
Medication: Ibuprofen	0.4	0.5	2.1	-0.9	-0.9	-1.4	-0.8	-0.6	0.1	-0.0	-0.8	-0.4	0.3	-0.3
Medication: Omeprazole	0.4	0.4	1.3	-0.7	-0.5	-1.0	-0.4	-1.1	0.3	-0.0	-0.9	0.4	0.7	-0.2
Pulse rate, automated reading	0.4	1.4	4.3	-0.3	0.6	-2.1	-0.3	-1.4	1.7	1.0	-0.5	0.8	2.1	-0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.2	-0.0	-0.6	-1.0	-0.3	-1.1	0.8	1.0	0.0	0.4	-0.0	-0.6
Medication: Aspirin	0.4	0.5	2.1	-0.7	-0.4	-1.4	-0.9	-0.9	0.2	0.1	-0.6	-0.4	0.6	-0.8
Illnesses of father: Heart disease	0.4	0.6	1.7	-0.9	-0.1	-0.1	-0.5	0.2	-1.3	-1.2	-0.9	-1.1	-0.2	-0.4
Osteoporosis (self-reported)	0.4	0.5	1.6	0.2	-0.4	-0.7	-0.5	-0.2	-0.2	0.7	0.6	-1.1	-1.0	-1.3
Osteoarthritis (self-reported)	0.4	0.5	1.7	0.5	0.8	0.3	0.7	-1.1	0.9	0.7	0.1	1.3	0.2	-0.3
Illnesses of father: None of the above (group 1)	0.4	0.5	1.1	0.7	0.6	1.0	1.0	-0.0	0.5	0.5	0.5	1.1	0.1	0.5
Smoking status: Current	0.4	0.7	2.0	-1.1	-0.6	-0.4	-0.7	-1.2	-0.6	-1.1	-1.4	0.0	-0.3	-0.7
Medication: Paracetamol	0.4	0.6	2.6	0.0	-1.1	-0.0	0.2	-0.8	1.1	0.1	-0.3	1.6	0.4	1.0
Basal cell carcinoma (self-reported)	0.4	0.4	1.2	0.3	0.9	-0.6	0.3	0.0	1.1	0.7	0.3	0.6	1.1	0.5
Depression (Nagel 2018)	0.3	0.4	2.2	-0.1	0.5	-1.0	-0.6	0.0	-0.1	0.3	0.5	-1.5	0.1	-0.2
HDL Cholesterol	0.3	0.5	5.1	0.0	0.0	0.0	0.0	0.0	0.0	2.3	0.0	0.0	0.0	0.0
Blood Platelet Count	0.3	3.3	9.9	-1.9	0.1	-0.7	-1.5	1.0	-2.8	-2.2	-1.5	-3.1	-1.7	-1.1
Blood Red Count	0.3	2.8	12.0	0.1	0.5	-2.0	-0.1	-1.1	2.8	1.3	-0.1	1.7	3.5	0.8
Blood White Count	0.3	1.9	8.5	-0.7	0.7	1.5	-0.1	1.6	-1.8	-2.9	-1.0	-0.8	-0.5	1.0
Smoking Status	0.3	0.7	2.8	0.9	0.3	0.4	0.8	-0.7	1.3	0.6	0.5	1.7	0.8	0.4
Lung FEV1/FVC ratio	0.3	1.6	5.3	-0.9	-0.4	0.4	-0.7	0.1	-2.0	-1.7	-1.0	-1.4	-2.3	-0.9
Chronotype (morning person)	0.3	0.7	3.2	1.3	-0.3	0.2	0.1	1.1	0.5	1.1	1.8	-0.5	-0.5	0.1
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.3	-0.8	-0.1	-1.2	-0.6	0.7	0.0	-0.3	-0.4	-0.7	0.2	0.7
Hearing difficulty/problems: Yes	0.3	0.5	1.5	0.8	0.5	-0.1	0.4	0.0	1.2	1.0	0.9	0.8	0.8	0.3
Relative age of first facial hair	0.3	0.6	1.1	-0.5	-1.1	-0.4	-1.0	-0.2	-0.7	-0.7	-0.4	-0.9	-1.0	-0.7
Vitamin and mineral supplements	0.3	0.4	1.2	0.5	0.4	0.6	0.6	0.0	0.8	0.5	0.4	1.1	0.5	0.7
Current tobacco smoking	0.3	0.6	1.3	-1.0	-0.5	-0.7	-0.8	-0.9	-0.6	-0.8	-1.1	-0.3	-0.2	-0.7
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.7	-0.6	-1.0	-0.9	-1.0	-1.2	-0.4	-0.2	-0.7	-0.5	-0.6	-1.3
Impedance of leg (left)	0.3	1.4	6.0	-0.6	-0.6	-0.3	-1.0	1.3	-1.7	-0.7	0.0	-2.5	-1.2	-0.7
Trunk fat mass	0.3	1.2	4.2	0.5	-0.0	1.6	1.2	0.4	0.7	-0.4	-0.0	2.0	0.3	2.0
Hair/balding pattern: Pattern 2	0.3	0.4	1.4	-0.1	-0.2	-0.3	-0.0	-1.2	0.5	0.0	-0.5	0.8	1.2	-0.3
Fluid intelligence score	0.3	0.6	1.8	0.7	0.2	-0.7	-0.1	-0.3	1.3	0.8	0.7	0.6	1.4	-0.1
Impedance of arm (right)	0.3	1.5	5.3	0.5	-0.2	1.0	-0.0	1.0	-1.7	0.1	1.1	-1.9	-2.3	-1.3
Noisy workplace	0.3	0.4	2.0	-0.3	-0.6	0.3	0.2	-1.4	-0.1	0.2	-0.6	0.8	-0.7	-0.5
Illnesses of mother	0.3	0.4	1.2	0.8	-0.2	0.3	0.5	-0.2	0.7	1.1	0.8	0.7	-0.0	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.8	3.1	0.5	0.6	1.8	0.6	1.3	-1.0	-0.8	0.5	-0.3	-0.9	0.5
Hair/balding pattern: Pattern 4	0.3	0.7	3.2	0.5	0.2	1.1	0.8	1.1	0.4	-0.4	0.4	0.9	0.4	1.8
Birth weight	0.3	0.7	2.4	-0.2	-0.7	1.1	-0.1	1.0	-0.5	-1.5	-0.4	0.2	-0.6	1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.3	-0.7	0.3	-0.2	-0.0	-0.2	0.2	-1.2	-1.2	0.7	0.4	0.8
Health satisfaction	0.3	0.4	1.6	0.1	0.4	-0.3	0.4	0.2	1.0	0.1	-0.1	0.9	1.3	1.1
Emphysema/chronic bronchitis	0.3	0.3	1.6	-0.3	-1.3	-0.4	-0.3	-0.5	0.4	-0.2	-0.4	0.5	-0.5	0.5
Angina (self-reported)	0.3	0.5	0.9	-0.9	0.2	-0.6	-0.5	0.1	-0.8	-0.9	-0.9	-0.9	-0.6	-0.2
Alcohol intake frequency.	0.3	0.7	2.3	-1.2	-0.8	-0.4	-0.9	0.2	-0.9	-1.5	-1.2	-0.6	-0.2	0.3
Overall health rating	0.3	0.6	2.2	-0.0	-0.4	-0.5	0.0	-0.9	1.3	0.1	-0.4	1.5	1.0	0.7
Family relationship satisfaction	0.3	0.4	1.2	0.8	0.1	0.7	0.2	1.1	0.1	0.1	1.1	-0.2	-0.7	0.5
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.9	0.6	-0.9	0.7	0.1	-0.1	-0.2	0.4	0.7	0.1	-0.9	-0.4
Friendships satisfaction	0.3	0.4	1.4	0.3	-0.9	-0.4	-0.3	-0.7	0.2	0.9	0.4	-0.0	-1.2	-0.8
Qualifications: nursing, teaching	0.3	0.5	1.9	0.6	0.9	1.4	0.9	0.8	-0.4	-0.1	0.6	0.1	-0.7	0.3
Mother’s age at death	0.3	0.4	1.7	0.4	-0.5	-0.4	-0.4	-0.5	-0.1	0.9	0.6	-0.6	-0.3	-1.3
Ever smoked	0.3	0.6	1.7	1.0	0.4	0.8	0.8	-0.3	1.0	0.7	0.8	1.3	0.2	0.3
Average weekly beer plus cider intake	0.3	0.4	1.3	-0.5	0.4	-0.2	-0.0	0.4	0.3	-0.8	-0.7	0.4	1.2	1.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.1	-0.4	-0.6	-0.9	-0.4	-1.1	0.4	0.2	-0.5	0.3	0.3	-0.4
Ovarian Cancer	0.2	0.2	0.8	0.4	-0.4	0.8	0.5	-0.5	0.3	0.4	0.3	0.9	-0.4	0.1
Prostate Cancer	0.2	0.3	1.3	-0.2	0.2	-0.4	-0.3	0.4	-0.6	0.1	0.2	-1.1	-0.8	-0.6
BMI	0.2	1.2	3.8	-1.6	-1.0	-0.6	-0.9	-1.2	-0.8	-1.5	-1.9	0.1	-0.6	-0.3
Waist Hip Ratio (WHR)	0.2	0.9	3.6	-0.6	-0.1	1.0	0.1	1.0	-0.5	-1.9	-0.9	0.5	0.6	1.7
Lung FVC	0.2	0.8	2.4	-1.0	-0.3	-1.0	-0.7	-1.6	-0.5	-0.2	-1.2	-0.3	-0.3	-1.3
Tanning	0.2	2.0	7.2	-0.9	-0.7	-2.1	-1.5	-1.7	-0.7	0.6	-0.6	-1.6	-0.7	-2.7
Hand grip strength (left)	0.2	0.5	1.7	0.7	0.1	0.0	0.5	-0.5	1.0	1.3	0.8	0.8	0.0	-0.0
Medication: Co-codamol	0.2	0.2	0.7	-0.5	0.0	0.2	0.3	-0.5	-0.0	-0.6	-0.8	0.8	0.1	0.5
Townsend deprivation index at recruitment	0.2	0.2	0.9	-0.4	0.1	-0.3	-0.1	-1.0	0.2	-0.4	-0.8	0.6	0.5	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.2	-0.1	0.0	-1.1	-0.4	0.3	0.3	0.8	0.3	-0.7	0.3	-0.2
Relative age voice broke	0.2	0.2	1.7	-0.1	-0.3	-0.1	-0.3	0.3	-0.4	-0.0	0.2	-0.7	-1.3	-0.3
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.8	0.0	-0.8	0.2	-0.2	-0.3	0.2	-0.7	-0.3	0.6	0.9	0.4
Multivitamins +/- minerals	0.2	0.3	0.9	-0.4	-0.1	-0.9	-0.4	-0.9	0.0	0.4	-0.4	-0.3	-0.1	-1.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.7	-0.7	-0.3	-0.1	-0.3	-0.1	-0.6	-0.7	-0.8	-0.3	-0.6	0.0
Body mass index (BMI)	0.2	1.0	2.8	-1.1	-0.7	-0.4	-0.2	-1.2	0.4	-0.9	-1.7	1.4	0.6	0.9
Arm fat percentage (right)	0.2	0.9	2.8	-1.2	-0.9	0.2	-0.4	-0.9	-0.9	-1.4	-1.7	0.3	-0.8	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.4	-0.5	0.4	-1.2	0.0	-0.4	0.7	0.4	-0.5	0.3	0.8	0.2
Asthma	0.2	0.4	1.4	-0.4	-0.5	-1.2	-0.5	-0.9	0.4	0.7	-0.3	-0.1	0.2	-0.7
Impedance of arm (left)	0.2	1.0	1.9	0.9	0.4	1.3	0.5	1.1	-1.1	0.5	1.3	-1.1	-1.4	-0.7
Arm fat mass (right)	0.2	0.7	3.1	-0.1	-0.5	1.1	0.6	-0.4	0.3	-0.8	-0.7	1.8	-0.0	1.3
Exposure to tobacco smoke at home	0.2	0.2	0.8	-0.5	-0.3	-0.5	-0.0	0.0	0.5	0.1	-0.4	0.4	0.9	0.8
Peak expiratory flow (PEF)	0.2	0.5	1.1	0.9	0.9	0.6	0.8	-0.2	0.9	0.7	0.7	1.1	0.6	0.3
Pulse wave reflection index	0.2	0.2	0.8	0.1	-0.4	0.2	0.4	-0.8	0.4	0.7	-0.0	0.9	-0.3	0.1
Headache pain in last month	0.2	0.3	1.0	-0.5	-0.3	-1.0	-0.4	-0.6	0.6	0.2	-0.6	0.4	0.6	0.1
Gout (self-reported)	0.2	0.3	1.0	-0.6	0.4	-0.9	-0.5	-0.5	0.2	-0.2	-0.7	-0.0	1.0	-0.3
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.7	-0.5	-0.8	-0.5	-0.8	-0.0	-0.5	-0.8	-0.5	-0.7	-0.0	-0.3
High blood pressure (siblings)	0.2	0.3	0.7	-0.8	-0.9	-0.5	-0.3	-0.1	-0.0	-0.4	-0.8	0.2	0.3	0.7
Forced vital capacity (FVC), Best measure	0.2	0.8	3.3	0.9	0.9	1.8	0.9	1.3	-0.4	-0.4	0.8	0.2	-0.3	0.8
Worry too long after embarrassment	0.2	0.4	1.4	0.0	-0.1	-0.5	0.2	-0.2	0.9	0.5	-0.0	0.8	1.2	0.7
Neck or shoulder pain in last month	0.2	0.3	1.3	-0.4	-0.5	-1.1	-0.4	-0.4	0.7	0.4	-0.3	0.3	0.7	0.3
Migraine (self-reported)	0.2	0.2	0.7	-0.5	-0.8	0.2	-0.2	-0.2	-0.6	-0.6	-0.5	-0.1	-0.5	-0.0
Medication: Seretide 50 evohaler	0.2	0.2	0.7	-0.1	-0.9	-0.6	-0.6	-0.6	0.3	0.2	-0.0	0.0	0.1	-0.5
Whole body fat mass	0.2	0.8	3.0	-0.1	-0.3	1.1	0.7	-0.0	0.4	-0.7	-0.6	1.7	0.2	1.7
Leg fat mass (right)	0.2	0.7	3.1	-0.3	-0.5	0.7	0.6	-0.5	0.6	-0.5	-0.8	1.8	0.5	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.9	-0.7	0.0	-1.0	-0.6	-0.7	0.1	-0.1	-0.7	-0.1	0.4	-0.5
Diabetes diagnosed by doctor	0.2	0.4	1.3	-1.0	-0.5	-0.8	-0.6	-0.6	-0.2	-0.6	-1.1	-0.0	-0.1	0.0
Commuting to job workplace: Walk	0.2	0.2	0.8	-0.5	-0.6	-0.2	-0.4	0.2	-0.2	-0.9	-0.6	-0.1	0.5	0.6
Mineral and other dietary supplements	0.2	0.3	1.6	-0.0	-0.2	0.4	0.5	-1.3	0.2	0.4	-0.4	1.1	-0.3	-0.3
Asthma (self-reported)	0.2	0.4	1.7	-0.5	-0.5	-1.3	-0.6	-1.0	0.3	0.6	-0.4	-0.1	0.2	-0.8
Arm fat mass (left)	0.2	0.7	3.3	-0.1	-0.2	1.0	0.7	-0.5	0.4	-0.7	-0.7	1.8	0.4	1.3
Number of self-reported non-cancer illnesses	0.2	0.3	0.9	-0.1	0.4	-0.2	0.3	-0.0	0.7	0.1	-0.2	0.7	0.9	0.8
Financial situation satisfaction	0.2	0.3	1.0	-0.7	0.1	0.0	-0.1	0.3	-0.5	-1.0	-0.8	-0.2	0.1	0.5
Leg fat percentage (left)	0.2	0.8	2.8	-1.4	-1.1	-0.4	-0.6	-0.5	-0.7	-1.2	-1.7	0.1	-0.2	0.4
Irritability	0.2	0.4	1.4	-0.6	0.4	-0.4	-0.6	0.3	-0.8	-0.6	-0.4	-1.2	-0.4	-0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.9	-0.4	-0.1	-0.4	-0.5	-0.6	-0.5	-0.3	-0.5	-0.5	0.0	-0.9
Diastolic blood pressure, automated reading	0.2	0.6	2.1	-0.4	-0.6	-0.3	0.2	-0.1	0.8	-0.3	-0.6	1.2	1.0	1.5
Commuting to job workplace: Cycle	0.2	0.2	0.6	0.6	-0.0	0.6	0.5	-0.2	0.4	0.4	0.5	0.6	-0.8	0.1
Cholesterol lowering medication	0.2	0.3	1.1	-0.4	0.0	-1.1	-0.4	-0.8	0.5	0.4	-0.4	0.1	0.7	-0.5
Alcohol drinker status: Previous	0.2	0.3	1.3	-0.2	-0.2	-0.1	0.2	-1.1	0.4	-0.1	-0.6	1.0	-0.1	0.0
Impedance of whole body	0.2	0.9	2.5	0.4	-0.0	0.8	0.0	1.4	-1.2	-0.1	0.9	-1.6	-1.2	-0.4
Leg fat mass (left)	0.2	0.7	2.1	-0.5	-0.5	0.7	0.4	-0.2	0.3	-0.9	-0.9	1.5	0.4	1.4
Alzheimer’s Disease (including proxy)	0.1	0.2	0.5	-0.4	-0.7	0.1	-0.2	-0.4	-0.1	-0.6	-0.7	0.5	-0.4	0.3
Breast Cancer	0.1	0.3	0.8	0.6	0.0	0.6	0.5	0.7	0.0	0.6	0.9	-0.1	-0.8	0.2
Neuroticism (2016)	0.1	0.1	0.3	-0.2	-0.2	-0.6	-0.3	0.0	0.1	0.6	0.1	-0.4	-0.3	-0.2
Primary Biliary Cirrhosis	0.1	0.2	2.1	0.0	0.0	0.0	0.0	0.0	0.0	1.5	0.0	0.0	0.0	0.0
Allergy or Eczema	0.1	0.2	0.4	-0.4	-0.3	-0.4	-0.4	-0.5	-0.1	-0.6	-0.6	0.1	0.1	-0.2
Cardiovascular Disease	0.1	0.3	1.1	-0.2	-0.4	-0.6	0.0	-0.6	0.8	0.2	-0.4	0.8	1.1	0.5
Respiratory disease	0.1	0.1	0.8	-0.3	-0.1	-0.9	-0.3	-0.0	0.4	0.2	-0.2	-0.1	0.4	0.2
Diabetes (father)	0.1	0.1	0.4	0.1	-0.5	0.3	0.2	0.4	0.1	0.1	0.2	0.2	0.2	0.6
Impedance of leg (right)	0.1	0.6	2.2	0.2	-0.1	0.3	-0.2	1.3	-1.0	-0.1	0.7	-1.5	-0.7	-0.3
Trunk fat percentage	0.1	0.5	2.2	-0.2	-0.3	1.0	0.7	0.2	0.1	-0.6	-0.5	1.2	0.0	1.5
Hand grip strength (right)	0.1	0.3	0.9	0.2	-0.3	-0.3	0.1	-0.9	0.8	0.9	0.1	0.8	0.2	-0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	-0.2	0.4	-0.3	-0.3	0.1	-0.2	-0.2	-0.2	-0.5	0.5	-0.3
High blood pressure	0.1	0.2	0.4	-0.2	-0.6	-0.2	-0.1	-0.2	0.5	-0.1	-0.3	0.7	0.4	0.6
High blood pressure (mother)	0.1	0.1	0.4	0.5	0.5	0.1	-0.0	0.5	0.1	0.3	0.7	-0.4	0.2	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.8	-0.7	-0.0	-0.9	-0.6	0.0	0.2	-0.6	-0.8	-0.1	0.5	0.4
Qualifications: None of the above	0.1	0.3	2.0	-0.4	-1.4	-0.7	-0.4	-0.3	0.1	0.4	-0.3	-0.0	-0.4	0.1
Mouth/teeth dental problems	0.1	0.2	0.8	0.5	0.5	0.2	0.3	-0.4	0.5	0.4	0.3	0.5	0.9	-0.3
Happiness	0.1	0.1	0.6	-0.0	-0.8	-0.2	-0.3	0.3	-0.0	-0.0	0.1	-0.2	-0.2	0.3
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.4	0.4	-0.5	0.2	0.2	-0.7	0.4	0.4	0.3	0.6	-0.2	-0.2
Medication: Amlodipine	0.1	0.2	0.7	-0.2	0.5	0.0	-0.0	0.2	0.1	-0.7	-0.4	0.2	0.8	0.5
Body fat percentage	0.1	0.5	1.2	-0.8	-0.7	0.4	0.1	-0.3	-0.3	-0.9	-1.1	0.8	-0.2	0.9
Leg fat percentage (right)	0.1	0.4	1.5	-0.9	-0.9	-0.1	-0.2	-0.6	-0.2	-0.8	-1.2	0.6	0.2	0.6
Number of full sisters	0.1	0.1	0.3	0.4	0.2	0.5	0.5	-0.2	-0.0	0.4	0.3	0.3	-0.1	-0.1
Supplements: Vitamin C	0.1	0.1	0.3	0.2	-0.3	0.0	0.2	-0.6	0.3	0.5	0.1	0.4	-0.1	-0.3
Hypertension (Self-reported)	0.1	0.2	0.5	-0.2	-0.6	-0.3	-0.1	-0.5	0.6	-0.1	-0.4	0.7	0.5	0.5
Arm fat percentage (left)	0.1	0.5	1.9	-0.9	-0.5	0.3	-0.0	-0.7	-0.5	-1.1	-1.4	0.7	-0.3	0.4
Long-standing illness, disability or infirmity	0.1	0.2	0.8	-0.1	-0.1	-0.2	0.1	-0.6	0.6	-0.1	-0.4	0.9	0.7	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.5	0.3	0.1	-0.2	0.3	0.1	0.6	0.7	0.3	0.3	0.1	0.3
Hearing aid user	0.1	0.2	0.5	0.2	0.5	0.3	0.3	0.7	-0.3	0.3	0.4	-0.5	-0.3	0.1
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.6	0.2	0.4	0.3	-0.0	0.4	-0.5	0.1	0.4	-0.8	-0.3	-0.6
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	-0.7	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	-0.5	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	-0.7	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	1.4	4.0	0.5	1.1	1.9	1.5	1.4	-0.1	-0.9	0.1	1.0	-0.1	2.0
Comparative body size at age 10	0.0	0.1	0.5	0.0	-0.2	-0.2	-0.1	-0.5	0.5	-0.1	-0.2	0.5	0.7	0.1

Hub : Genes

LOC652276

Models

Trait associations