TWAS hub - LOC84740

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.2624	0.0567	5.6e-17	0.222	0.181	0.221	NA	0.222	1.5e-24	6.7e-20	1.6e-24	NA	1.3e-24
2	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1130	0.0570	8.0e-03	0.018	0.030	0.052	NA	0.041	3.1e-02	7.3e-03	5.9e-04	NA	2.2e-03
3	TCGA	Brain Lower Grade Glioma	0.0546	0.0256	1.3e-03	0.024	0.019	0.020	NA	0.030	9.4e-04	2.7e-03	2.3e-03	NA	2.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Family relationship satisfaction	4.0	4.9	8.5	1.6	2.9	1.9
Age at First Birth	3.7	5.4	12.6	1.5	-1.2	-3.6
Smoking status: Previous	3.5	5.2	8.4	1.4	2.9	2.3
Ever depressed for a whole week	3.3	4.1	7.0	-2.6	-0.8	2.1
Deep venous thrombosis (DVT) (self-reported)	2.8	3.6	10.5	-0.5	0.1	3.2
Mean Putamen Volume	2.6	3.0	6.1	-1.5	-2.5	-0.9
Blood clot in the leg (DVT)	2.6	3.4	10.1	-0.3	0.1	3.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.6	3.1	8.0	-0.3	-2.8	-1.1
Systolic Blood Pressure	2.5	12.5	19.7	4.4	1.3	-4.0
Angina	2.5	3.2	6.8	1.6	-0.6	-2.6
Coronary Artery Disease (CAD)	2.4	2.9	7.4	1.0	2.7	-0.4
Past tobacco smoking	2.4	4.5	6.7	-1.8	-2.6	-1.9
Angina (self-reported)	2.4	3.1	6.4	1.6	-0.7	-2.5
Age at last live birth	2.4	3.5	10.0	-0.1	0.6	-3.2
Qualifications: nursing, teaching	2.3	3.6	7.5	0.6	1.7	-2.7
Medication: Simvastatin	2.2	3.2	5.1	2.2	-0.1	-2.3
Medication: Lansoprazole	2.2	2.5	6.7	-0.7	-2.6	-0.6
Lung FEV1/FVC ratio	2.1	10.6	28.9	1.6	-0.6	-5.4
Mouth/teeth dental problems	2.1	3.2	5.5	2.0	0.5	-2.3
Ever smoked	2.0	3.4	6.5	1.0	2.5	1.7
Hair/balding pattern: Pattern 3	1.9	2.9	7.1	1.1	-0.5	-2.7
Mouth/teeth dental problems: Dentures	1.9	3.3	5.9	-2.4	-1.9	0.4
Medication: Ramipril	1.8	2.3	6.8	2.6	0.0	-0.1
Father’s age at death	1.7	2.3	4.3	-2.1	0.5	1.6
Falls in the last year	1.7	2.3	5.8	-1.0	-2.4	-0.2
Happiness	1.7	2.0	3.3	-0.5	1.6	1.8
Basal cell carcinoma (self-reported)	1.7	2.0	4.1	-2.0	-0.8	1.2
Ovarian Cancer	1.6	2.1	3.8	1.4	0.7	1.9
Medication: Co-codamol	1.6	1.8	3.3	-1.8	-1.5	0.0
Pain all over the body in last month	1.6	1.7	2.7	-1.6	0.4	1.5
Serious illness, injury or assault of a close relative in last 2 years	1.6	1.8	3.2	1.1	-1.8	-1.0
Eye problems/disorders: None of the above	1.6	1.8	3.9	2.0	1.1	0.6
Friendships satisfaction	1.6	2.0	2.6	1.0	1.5	1.6
Supplements: Fish oil (including cod liver oil)	1.6	2.0	3.8	1.5	-0.2	-2.0
Heart attack/myocardial infarction (self-reported)	1.6	2.1	4.4	1.3	-0.5	-2.1
Chronotype (morning person)	1.5	3.4	7.1	2.7	0.4	-1.7
Ever unenthusiastic/disinterested for a whole week	1.5	1.9	3.1	-1.4	-1.8	0.8
Qualifications: None of the above	1.5	3.3	6.9	-0.6	-1.6	2.6
Medication: Cholesterol lowering	1.5	2.3	4.9	2.2	-0.2	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.2	3.3	-1.2	-1.8	1.4
Migraine (self-reported)	1.5	1.8	3.3	-1.1	-1.1	1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	3.6	-1.9	0.6	1.1
Miserableness	1.5	2.5	4.6	-1.7	-2.1	0.3
Ever taken oral contraceptive pill	1.5	1.7	2.7	1.6	-0.3	-1.5
Fasting Glucose	1.4	1.6	3.8	0.1	1.1	2.0
Waist Hip Ratio (WHR)	1.4	6.3	9.7	0.8	2.9	3.1
Average weekly spirits intake	1.4	1.7	2.9	-0.7	-1.4	1.7
Heart attack	1.4	1.8	3.5	1.4	-0.3	-1.9
Number of live births	1.4	2.0	3.8	-1.4	0.2	2.0
High blood pressure (siblings)	1.4	2.1	3.5	1.1	-1.2	-1.9
Illnesses of father: Heart disease	1.4	1.9	3.0	1.7	-0.4	-1.6
Pack years adult smoking proportion	1.3	2.0	5.8	0.1	-2.4	0.4
Length of working week for main job	1.3	1.5	3.3	1.8	-1.0	0.4
Number of children fathered	1.3	1.5	2.4	1.6	0.7	-1.2
Age at first live birth	1.3	2.4	5.9	-0.4	1.0	-2.4
Health satisfaction	1.3	1.7	3.7	-0.9	0.8	1.9
Mouth/teeth dental problems: Loose teeth	1.3	1.5	3.1	0.5	1.8	1.1
Heart disease (mother)	1.3	1.5	3.8	0.8	0.4	-1.9
Pack years of smoking	1.3	1.9	5.4	0.2	-2.3	0.3
Systolic blood pressure, automated reading	1.2	3.5	5.9	2.4	0.9	-1.9
Impedance of arm (left)	1.2	5.4	13.8	-0.4	1.5	3.7
Osteoporosis (self-reported)	1.2	1.4	3.1	1.0	1.8	0.5
Eye problems/disorders: Glaucoma	1.2	1.4	3.0	-1.1	-1.7	0.0
Bipolar Disorder or Schizophrenia	1.1	2.6	5.2	2.3	1.0	1.3
Schizophrenia (2018)	1.1	2.3	3.7	1.9	0.8	1.6
Prostate Cancer	1.1	1.6	2.2	-0.9	1.5	1.3
Neuroticism (2016)	1.1	1.5	4.3	-2.1	-0.4	0.2
Respiratory disease	1.1	2.4	3.7	-1.6	-1.9	-1.0
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	1.6	-1.0	-1.0	1.2
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	2.9	0.8	-0.9	-1.7
Illnesses of siblings	1.1	1.6	2.0	-1.1	1.2	1.4
Birth weight of first child	1.1	1.9	3.0	-1.7	-0.2	1.7
Knee pain experienced in last month	1.1	1.7	2.2	1.5	-1.0	-1.4
Commuting to job workplace: Cycle	1.1	1.4	3.6	0.2	-0.7	-1.9
Cholesterol lowering medication	1.1	1.6	4.4	0.6	-0.1	-2.1
Heart disease (siblings)	1.1	1.3	2.6	0.9	1.6	-0.7
Average weekly fortified wine intake	1.0	1.2	3.0	-0.4	0.6	-1.7
Impedance of arm (right)	1.0	4.6	13.0	-0.4	0.7	3.6
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	2.0	-1.2	-1.2	1.4
Noisy workplace	1.0	1.2	2.2	0.9	0.7	1.5
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.5	-0.1	0.3	1.9
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	3.0	-0.3	1.2	-1.7
Neck or shoulder pain in last month	1.0	1.4	4.1	0.5	0.0	2.0
Medication: Ibuprofen	1.0	1.2	2.4	-0.8	-1.6	0.8
Medication: Aspirin	1.0	1.4	1.5	1.2	-1.1	-1.1
Pain type(s) experienced in last month: Hip pain	1.0	1.2	2.2	0.3	-1.5	-1.1
Irritability	1.0	1.6	2.8	1.7	-0.7	-1.2
Age started oral contraceptive pill	1.0	1.2	3.2	0.5	0.5	-1.8
Alzheimer’s Disease (in mother)	0.9	1.1	2.3	0.4	1.5	0.9
HbA1C	0.9	1.0	2.4	-0.7	0.3	-1.5
Lupus	0.9	1.3	2.6	-1.1	-0.4	1.6
Rheumatoid Arthritis	0.9	1.2	1.8	1.3	1.4	0.1
Diabetes (father)	0.9	1.1	2.6	-0.8	-0.3	1.6
Diabetes (mother)	0.9	1.1	2.4	0.2	0.9	1.6
Chronic bronchitis/emphysema (father)	0.9	1.0	1.8	1.3	0.4	1.0
Pulse rate	0.9	1.5	3.7	-0.7	-0.6	-1.9
Qualifications: A levels/AS levels or equivalent	0.9	2.0	5.5	-0.1	2.3	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	2.3	-0.7	-0.8	1.5
Leg pain on walking	0.9	1.1	2.5	1.6	0.6	-0.7
Medication: Aspirin	0.9	1.2	1.3	1.1	-1.1	-1.0
Tinnitus: Yes, now most or all of the time	0.9	1.0	2.6	-0.3	0.6	1.6
Unable to work because of sickness or disability	0.9	1.2	3.1	-0.6	-1.8	0.4
Alzheimer’s Disease (including proxy)	0.8	1.1	1.6	0.4	1.2	1.3
Crohns Disease (2017)	0.8	1.8	3.5	-1.9	0.1	1.4
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.5	-0.5	-1.6	0.1
Smoking Status	0.8	1.9	2.7	1.5	0.8	1.6
Fed-up feelings	0.8	1.4	3.0	-0.2	-1.1	1.7
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.6	-0.4	-0.1	-1.6
Alcohol usually taken with meals	0.8	1.3	3.2	0.9	0.1	-1.8
Had other major operations	0.8	1.0	1.6	-1.0	-0.7	1.3
Lung cancer (father)	0.8	1.0	2.7	1.6	-0.3	-0.5
Number of full brothers	0.8	1.1	3.1	-1.8	-0.0	0.3
Worry too long after embarrassment	0.8	1.4	2.6	-1.6	-0.4	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.1	3.2	0.2	0.0	1.8
Ever had bowel cancer screening	0.8	0.9	1.6	1.3	-0.8	0.7
Mineral and other dietary supplements	0.8	1.1	1.4	-1.2	1.0	1.0
High cholesterol (Self-reported)	0.8	1.3	2.9	1.7	0.9	-0.4
Depressed Affect (Nagel 2018)	0.7	1.4	2.7	-0.9	-0.9	1.6
Depression (Nagel 2018)	0.7	1.0	2.2	-0.9	-0.3	1.5
HDL Cholesterol	0.7	1.1	2.5	1.6	0.5	-0.8
Blood Red Count	0.7	6.9	13.5	2.5	3.7	1.0
Sensitivity / hurt feelings	0.7	1.2	3.0	0.1	-1.7	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.5	-0.3	0.1	1.6
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	1.7	-0.1	-0.8	1.3
Arm fat percentage (right)	0.7	2.9	3.6	-1.7	-1.5	1.9
Trunk fat-free mass	0.7	4.1	9.7	1.6	-0.2	-3.1
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	6.3	-0.4	-0.8	-2.5
Trunk predicted mass	0.7	4.1	9.8	1.6	-0.2	-3.1
Headache pain in last month	0.7	1.2	2.5	1.6	-0.5	1.0
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	2.1	-0.5	-1.5	-1.2
Medication: Blood pressure	0.7	1.2	2.6	1.6	-0.2	1.0
Hearing aid user	0.7	0.8	1.9	-0.5	-1.4	-0.4
Medication: Bendroflumethiazide	0.7	1.1	1.8	1.3	-1.2	-0.2
Illnesses of father: High blood pressure	0.7	0.8	1.2	1.1	-0.5	1.0
Arm fat-free mass (left)	0.7	3.5	8.6	1.2	-0.7	-2.9
Alcohol drinker status: Previous	0.7	0.8	1.1	-0.8	-0.9	1.0
Irritable Bowel Disease (IBD)	0.6	1.5	3.6	-0.9	0.5	1.9
Ulcerative Colitis (UC)	0.6	1.1	3.3	-0.1	0.3	1.8
Schizophrenia (2014)	0.6	1.3	3.4	1.8	-0.8	0.1
Hypothyroidism (self reported)	0.6	1.3	2.8	-0.7	-1.7	-0.8
Number of treatments/medications taken	0.6	1.1	1.7	0.9	-0.9	1.3
Trunk fat percentage	0.6	2.4	5.6	-1.0	-0.8	2.4
Townsend deprivation index at recruitment	0.6	0.9	1.7	-1.3	-0.8	0.7
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	1.2	0.3	-1.1	-0.9
Had menopause	0.6	0.8	1.7	-0.8	0.2	1.3
Neuroticism score	0.6	1.3	3.5	-0.2	-0.6	1.9
Asthma	0.6	1.2	2.2	-0.8	-0.8	-1.5
Standing height	0.6	5.6	11.2	3.3	1.8	-1.5
Exposure to tobacco smoke at home	0.6	0.7	1.3	-0.1	-1.2	-0.9
Breastfed as a baby	0.6	0.7	1.5	1.2	0.7	-0.4
Medication: Paracetamol	0.6	1.0	3.1	0.2	0.0	1.7
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	2.5	-1.6	0.4	-0.4
Medication: Ventolin 100micrograms inhaler	0.6	0.8	1.6	-1.3	-0.0	0.9
Qualifications: College or University degree	0.6	2.0	5.0	-0.9	0.4	-2.2
Chest pain or discomfort	0.6	0.8	2.0	0.3	-0.6	-1.4
Arm fat percentage (left)	0.6	2.6	4.0	-1.6	-1.0	2.0
Loneliness, isolation	0.6	0.8	1.2	-0.7	-0.9	1.1
Breast cancer (self-reported)	0.6	0.7	1.6	0.4	-1.3	0.5
Guilty feelings	0.6	0.9	1.7	-0.5	0.8	1.3
Commuting to job workplace: Public transport	0.6	0.7	1.4	-0.6	1.2	0.5
Medication: Paracetamol	0.6	0.9	1.6	0.7	-0.7	1.3
Number of operations (self-reported)	0.6	0.9	2.4	0.4	-1.5	-0.5
Myopia	0.6	0.8	1.8	1.3	0.6	-0.5
Supplements: Calcium	0.6	0.7	1.4	-0.2	-0.8	1.2
Impedance of whole body	0.6	3.2	8.4	-0.0	1.0	2.9
Arm predicted mass (left)	0.6	2.8	7.0	1.0	-0.7	-2.6
Neuroticism (Nagel 2018)	0.5	1.2	1.3	-1.1	-1.1	1.1
Schizophrenia vs Biploar Disorder	0.5	0.7	1.0	0.6	-1.0	-0.8
Heel T-Score	0.5	3.6	6.0	-0.5	-2.4	-2.1
Neuroticism	0.5	1.3	2.3	-1.0	-0.7	1.5
Hearing difficulty/problems: Yes	0.5	0.7	1.5	0.8	-0.4	1.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.0	0.4	-0.8	-1.0
Medication: Levothyroxine sodium	0.5	0.9	2.2	-0.8	-1.5	-0.1
Time employed in main current job	0.5	0.6	1.2	-0.5	-1.1	-0.6
Illnesses of mother	0.5	0.7	1.0	-1.0	-0.2	1.0
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.2	0.8	1.1	0.6
Body fat percentage	0.5	1.8	3.6	-0.9	-1.0	1.9
Medication for pain relief, constipation, heartburn	0.5	0.8	1.9	0.2	1.4	-0.7
Arm predicted mass (right)	0.5	2.7	5.7	1.5	0.3	-2.4
Suffer from ‘nerves’	0.5	0.8	1.7	0.6	-1.3	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.5	0.0	-0.7	-1.2
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.0	-0.9	1.0	0.2
Supplements: Vitamin C	0.5	0.5	0.8	-0.9	-0.8	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.1	-0.2	-1.1	-0.6
Medication for cholesterol	0.5	0.8	0.9	-1.0	-0.9	-0.9
Asthma (self-reported)	0.5	0.9	1.4	-1.0	-0.7	-1.2
Illnesses of father: None of the above (group 1)	0.5	0.7	1.5	-1.2	0.3	0.6
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.0	-0.7	-1.0	0.2
Bipolar Disorder (2018)	0.4	0.6	1.5	1.2	0.6	0.1
Alzheimer’s Disease (in father)	0.4	0.5	1.0	-0.4	-0.4	1.0
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.1	-0.2	0.5	1.4
Ever used hormone-replacement therapy (HRT)	0.4	0.6	1.3	-1.2	0.2	0.6
Hand grip strength (right)	0.4	1.1	2.4	0.7	1.5	-0.7
Age when periods started (menarche)	0.4	1.0	3.1	-1.8	-0.1	0.1
Serious illness, injury or assault to yourself	0.4	0.4	1.2	-0.3	-0.1	1.1
High blood pressure	0.4	1.2	3.0	1.7	0.6	0.3
Stomach or abdominal pain in last month	0.4	0.5	1.3	1.1	0.5	0.1
Medication: Atenolol	0.4	0.5	0.9	0.5	1.0	-0.4
Body mass index (BMI)	0.4	1.5	2.9	-1.3	-1.7	0.1
Worrier / anxious feelings	0.4	0.7	1.9	-1.4	-0.0	0.5
Depression (self-reported)	0.4	0.4	0.7	-0.5	-0.6	0.8
Prospective memory result	0.4	0.5	1.3	0.0	-0.1	1.2
Pulse wave Arterial Stiffness index	0.4	0.4	0.6	0.3	0.8	-0.8
Arm fat-free mass (right)	0.4	2.1	4.3	1.4	0.2	-2.1
Shortness of breath walking on level ground	0.4	0.5	0.9	0.9	-0.3	-0.6
Pulse rate, automated reading	0.4	1.4	2.9	-0.9	-0.6	-1.7
Number of full sisters	0.4	0.5	1.1	-0.6	-0.3	1.0
Whole body fat-free mass	0.4	2.4	5.5	1.2	-0.0	-2.4
Handedness (chirality/laterality): Left-handed	0.4	0.4	0.8	0.9	0.3	0.7
Mood swings	0.4	0.7	2.0	-0.1	-1.4	0.1
Eye problems/disorders: Cataract	0.4	0.4	1.1	0.1	1.1	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	0.9	-0.8	-0.3	1.0
Whole body water mass	0.4	2.4	5.4	1.4	-0.1	-2.3
Alcohol drinker status: Never	0.4	0.5	1.2	-0.3	1.1	-0.5
Reaction Time	0.3	0.6	1.5	0.1	1.2	0.6
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.9	-0.6	1.4	0.3
Primary Biliary Cirrhosis	0.3	0.4	0.7	-0.6	0.8	0.2
Blood Platelet Count	0.3	3.2	6.7	1.7	-2.6	-0.4
Blood White Count	0.3	2.5	5.5	2.3	-0.0	-1.4
Height	0.3	5.7	12.5	3.5	1.8	-1.2
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.0	0.2	-0.5	1.0
Supplements: Zinc	0.3	0.3	0.5	0.1	0.6	0.7
Medication: Metformin	0.3	0.4	0.9	-0.5	-0.2	0.9
Maternal smoking around birth	0.3	0.5	0.9	-0.7	0.1	1.0
Taking other prescription medications	0.3	0.5	1.1	-0.7	-1.0	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	1.2	-0.5	-1.1	-0.4
Qualifications: CSEs or equivalent	0.3	0.4	0.9	0.6	-1.0	-0.0
Multivitamins +/- minerals	0.3	0.3	0.9	-1.0	-0.2	-0.1
Supplements: Glucosamine	0.3	0.4	0.8	0.6	-0.9	0.2
Sitting height	0.3	2.2	4.5	2.1	1.4	-0.3
High blood pressure (mother)	0.3	0.4	0.7	0.6	-0.2	-0.9
Hair/balding pattern: Pattern 2	0.3	0.4	1.2	-0.2	-0.2	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.0	-1.0	-0.9	-0.0
Hip circumference	0.3	1.1	2.0	-0.0	-1.4	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	1.4	-1.1	-0.7	-1.2
Arm fat mass (right)	0.3	1.2	1.6	-1.0	-1.3	0.9
Pulse wave reflection index	0.3	0.4	0.6	0.4	0.8	-0.6
Glaucoma (self-reported)	0.3	0.3	0.7	-0.2	-0.9	0.4
Gout (self-reported)	0.3	0.5	0.8	0.9	0.8	-0.3
Birth weight	0.3	0.7	1.0	0.4	1.0	1.0
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.5	-0.7	-0.6	0.5
Leg fat percentage (right)	0.3	1.2	1.6	-1.0	-1.3	1.0
Pulse wave peak to peak time	0.3	0.3	0.8	0.1	-0.4	0.9
Hypertension (Self-reported)	0.3	0.8	2.3	1.5	0.3	0.2
Average weekly red wine intake	0.3	0.5	0.8	-0.8	0.9	0.1
Long-standing illness, disability or infirmity	0.3	0.5	0.7	0.8	0.8	0.3
Medication: Gliclazide	0.3	0.3	0.5	0.5	-0.7	0.4
Smoking status: Current	0.3	0.4	0.5	0.7	-0.6	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	0.9	-0.5	-1.0	-0.7
Arm fat mass (left)	0.3	1.3	1.7	-1.3	-1.2	0.9
Number of self-reported non-cancer illnesses	0.3	0.6	1.5	1.2	0.3	0.4
Wears glasses or contact lenses	0.3	0.4	0.8	0.5	0.2	-0.9
Financial situation satisfaction	0.3	0.3	1.0	0.1	0.2	1.0
Medication: Blood pressure	0.3	0.6	1.6	1.3	0.5	-0.0
Medication: Lisinopril	0.3	0.4	0.6	0.8	0.8	-0.1
Basal metabolic rate	0.3	1.6	3.7	1.0	-0.3	-1.9
Average weekly beer plus cider intake	0.3	0.4	0.6	0.7	0.4	0.8
Risk taking	0.3	0.4	0.9	-0.9	0.3	0.5
Fractured/broken bones in last 5 years	0.3	0.4	1.0	0.6	0.1	1.0
Diastolic blood pressure, automated reading	0.3	1.0	1.6	1.3	0.2	-1.1
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.7	-1.6	-0.3	0.1
Pain experienced in last month	0.3	0.5	1.5	-0.2	1.2	-0.1
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.1	-0.6	1.1	0.1
Worry (Nagel 2018)	0.2	0.5	0.8	-0.6	-0.6	0.9
Body Mass Index (BMI) (2010)	0.2	0.2	0.6	0.1	-0.8	-0.3
Crohns Disease (2012)	0.2	0.3	1.0	-1.0	-0.0	0.2
LDL Cholesterol	0.2	0.3	0.5	-0.5	-0.7	0.1
Ulcerative Colitis	0.2	0.2	0.6	0.3	0.1	0.8
Blood Eosinophil Count	0.2	1.4	2.2	0.0	-1.4	1.5
BMI	0.2	1.2	3.2	-0.6	-1.8	-0.2
Lung FVC	0.2	0.8	1.5	-1.0	-1.2	0.0
Hand grip strength (left)	0.2	0.5	0.7	0.6	0.7	-0.8
Vitamin and mineral supplements	0.2	0.2	0.5	0.4	0.7	0.3
Current tobacco smoking	0.2	0.4	0.5	0.4	-0.7	0.7
Relative age voice broke	0.2	0.2	0.6	-0.8	-0.3	-0.1
Impedance of leg (left)	0.2	1.0	2.1	0.6	0.6	1.5
Trunk fat mass	0.2	0.7	1.4	-0.3	-0.8	1.2
Number of incorrect matches in round	0.2	0.4	1.2	0.1	0.1	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.7	-0.2	-0.3	0.9
Hearing difficulty/problems with background noise	0.2	0.3	1.0	0.1	-1.0	-0.2
Tense / ‘highly strung’	0.2	0.4	0.9	1.0	-0.4	-0.4
Peak expiratory flow (PEF)	0.2	0.3	0.5	-0.7	-0.3	-0.7
Loud music exposure frequency	0.2	0.2	0.3	0.5	0.6	0.1
Medication: Amlodipine	0.2	0.3	0.6	-0.5	-0.1	0.8
Exposure to tobacco smoke outside home	0.2	0.2	0.6	-0.1	-0.8	-0.1
Comparative body size at age 10	0.2	0.5	0.8	0.9	-0.7	-0.5
Medication: Allopurinol	0.2	0.3	0.5	0.7	0.2	-0.6
Medication: Omeprazole	0.2	0.3	0.7	-0.2	0.4	0.8
Medication: Seretide 50 evohaler	0.2	0.3	0.5	-0.4	-0.4	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.5	0.5	0.3	-0.7
Alcohol intake frequency.	0.2	0.5	1.4	-0.1	0.5	1.2
Comparative height size at age 10	0.2	1.3	3.0	1.7	0.8	-0.3
Had major operations	0.2	0.2	0.4	0.4	-0.6	-0.4
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.7	0.4	0.8	0.1
Illnesses of siblings: Diabetes	0.2	0.3	0.7	-0.1	-0.9	-0.4
Diabetes diagnosed by doctor	0.2	0.3	0.7	-0.2	0.4	0.8
Back pain experienced in last month	0.2	0.3	0.6	-0.1	-0.8	-0.6
Average weekly champagne plus white wine intake	0.2	0.3	0.9	1.0	0.3	0.1
Medication: Atorvastatin	0.2	0.3	0.7	-0.4	-0.8	-0.1
Leg fat percentage (left)	0.2	0.8	1.3	-0.7	-1.1	0.8
Breast Cancer	0.1	0.3	0.8	-0.9	-0.1	-0.2
Triglycerides	0.1	0.2	0.5	-0.3	-0.7	-0.3
Cardiovascular Disease	0.1	0.3	0.8	0.9	0.4	-0.0
Relative age of first facial hair	0.1	0.3	0.6	-0.1	0.7	-0.5
Ever had hysterectomy (womb removed)	0.1	0.1	0.2	0.4	-0.3	-0.4
Medication for hormone replacement therapy	0.1	0.1	0.4	0.2	-0.1	0.6
Severe depression (siblings)	0.1	0.1	0.1	0.4	0.1	-0.2
Impedance of leg (right)	0.1	0.5	1.5	0.2	0.2	1.2
Leg fat-free mass (left)	0.1	0.6	1.1	0.7	-0.1	-1.1
Leg predicted mass (left)	0.1	0.4	0.8	0.7	-0.1	-0.9
Nervous feelings	0.1	0.3	0.7	0.4	0.8	0.1
Forced vital capacity (FVC)	0.1	0.5	1.3	-0.1	0.4	-1.2
Financial difficulties in last 2 years	0.1	0.2	0.6	-0.0	-0.2	-0.8
Diabetes (self-reported)	0.1	0.2	0.4	-0.3	-0.3	0.6
Fluid intelligence score	0.1	0.1	0.3	-0.3	0.6	0.1
Weight	0.1	0.3	0.6	0.3	-0.8	-0.5
Alcohol intake versus 10 years previously	0.1	0.1	0.3	0.6	-0.1	0.2
Forced vital capacity (FVC), Best measure	0.1	0.5	1.3	-1.1	-0.2	-0.2
Wheeze or whistling in the chest in last year	0.1	0.2	0.3	0.5	-0.3	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.3	-0.0	0.6	0.2
Emphysema/chronic bronchitis	0.1	0.2	0.5	0.7	0.1	-0.1
Whole body fat mass	0.1	0.6	1.0	-0.4	-0.7	1.0
Leg fat mass (right)	0.1	0.5	1.0	-0.6	-1.0	0.4
Overall health rating	0.1	0.1	0.3	0.2	-0.3	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.3	0.2	0.1	-0.6
Leg fat-free mass (right)	0.1	0.7	1.1	1.0	0.2	-1.0
Commuting to job workplace: Walk	0.1	0.1	0.2	-0.2	-0.3	0.4
Osteoarthritis (self-reported)	0.1	0.1	0.3	0.2	-0.5	-0.1
Leg predicted mass (right)	0.1	0.8	1.2	1.1	0.2	-1.0
Mother’s age at death	0.1	0.2	0.5	0.7	-0.2	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.2	0.1	0.2	0.5
Leg fat mass (left)	0.1	0.4	1.0	-0.4	-1.0	0.3
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Allergy or Eczema	0.0	0.1	0.2	0.2	-0.4	0.3
Hair Pigment	0.0	1.4	3.0	1.1	-1.7	-0.1
Tanning	0.0	0.5	0.8	-0.7	-0.9	0.4
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.0	-0.1	0.1	0.1
Waist circumference	0.0	0.1	0.2	-0.5	0.0	0.4
Allergy	0.0	0.0	0.0	0.1	-0.1	-0.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.2	-0.3	-0.4	-0.3
Mean time to correctly identify matches	0.0	0.1	0.1	0.2	0.4	0.0

Hub : Genes

LOC84740

Models

Trait associations