Hub : Genes

LONP2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0520 0.0200 3.0e-06 0.068 0.045 0.065 0.049 0.066 1.1e-08 3.0e-06 2.6e-08 1.1e-06 1.9e-08
2 GTEx Adipose Subcutaneous 0.0970 0.0460 3.7e-04 0.084 NA 0.049 NA 0.066 2.1e-07 NA 6.9e-05 NA 4.7e-06
3 GTEx Cells EBV-transformed lymphocytes 0.1510 0.0610 2.0e-04 0.123 NA 0.174 NA 0.170 8.1e-05 NA 2.6e-06 NA 3.4e-06
4 GTEx Esophagus Muscularis 0.2880 0.0940 2.9e-03 0.056 NA 0.009 NA 0.005 2.5e-04 NA 8.5e-02 NA 1.4e-01
5 GTEx Lung 0.2004 0.0679 2.1e-03 0.053 NA 0.086 NA 0.003 6.8e-05 NA 4.1e-07 NA 1.7e-01
6 GTEx Muscle Skeletal 0.1492 0.0590 6.1e-05 0.047 NA 0.025 NA 0.043 1.9e-05 NA 1.6e-03 NA 4.4e-05
7 GTEx Nerve Tibial 0.4097 0.0772 3.8e-07 0.187 NA 0.121 NA 0.042 2.7e-13 NA 6.4e-09 NA 5.5e-04
8 GTEx Skin Not Sun Exposed Suprapubic 0.2000 0.0870 5.3e-03 0.111 NA 0.046 NA 0.003 1.2e-06 NA 1.5e-03 NA 2.2e-01
9 GTEx Skin Sun Exposed Lower leg 0.3110 0.0710 1.8e-05 0.138 NA 0.133 NA -0.003 1.7e-11 NA 4.0e-11 NA 6.4e-01
10 GTEx Thyroid 0.2700 0.0620 7.2e-07 0.179 NA 0.152 NA 0.077 1.1e-13 NA 1.1e-11 NA 1.7e-06
11 METSIM Adipose 0.0464 0.0217 7.5e-04 0.024 0.017 0.032 0.021 0.034 1.2e-04 1.1e-03 1.1e-05 3.7e-04 7.4e-06
12 NTR Blood 0.0175 0.0070 1.5e-05 0.022 0.017 0.015 0.017 0.019 1.0e-07 2.6e-06 9.3e-06 2.5e-06 8.5e-07
13 YFS Blood 0.1858 0.0350 0.0e+00 0.120 0.162 0.175 0.171 0.182 5.3e-37 1.8e-50 5.0e-55 1.6e-53 3.3e-57
14 TCGA Prostate Adenocarcinoma 0.3786 0.1209 1.4e-04 0.039 0.040 0.046 NA 0.056 5.4e-05 4.6e-05 1.3e-05 NA 1.4e-06
15 TCGA Thyroid Carcinoma 0.0810 0.0470 6.9e-06 0.054 0.059 0.069 NA 0.067 5.3e-06 1.9e-06 3.1e-07 NA 4.2e-07

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 0.4 0.6 2.0 -0.0 0.4 0.8 -1.4 1.1 0.7 -0.7 -0.3 -0.2 -0.3 0.3 0.8 0.3 1.0 1.3
Bipolar Disorder or Schizophrenia 0.5 1.2 3.3 -0.4 1.5 0.6 -1.5 -0.3 1.1 -1.5 -1.0 -1.1 -0.7 -0.3 0.9 -0.3 1.6 1.8
Depressed Affect (Nagel 2018) 0.4 0.9 4.0 1.8 0.2 2.0 -0.1 0.5 1.1 -0.2 -1.4 -0.2 -0.1 0.6 1.2 0.8 -0.1 1.0
Depression (Nagel 2018) 0.7 1.1 5.0 2.1 0.4 2.2 0.3 -0.5 1.4 -0.2 -0.7 -0.8 -0.2 0.5 1.4 0.9 -0.4 0.7
Intelligence (Savage-Jansen 2018) 0.3 1.1 3.4 0.9 1.5 0.4 -0.8 -1.3 0.7 -1.5 -0.8 -1.8 -1.5 -0.7 0.4 -0.4 0.6 -0.7
Neuroticism (Nagel 2018) 1.2 2.9 7.5 2.7 -0.8 2.7 1.7 0.6 2.0 0.9 0.1 0.6 1.2 1.7 2.2 2.0 -1.5 1.8
Schizophrenia (2018) 0.5 1.0 2.7 -0.6 1.6 0.2 -0.9 -1.3 0.8 -1.4 -1.0 -1.3 -0.7 -0.6 0.4 -0.6 1.3 1.3
Schizophrenia vs Biploar Disorder 0.7 0.9 2.0 -1.3 -1.3 -1.4 0.7 1.0 -0.3 1.3 1.4 0.0 1.4 0.6 -0.3 0.2 -0.4 0.8
Worry (Nagel 2018) 1.2 2.5 7.3 2.7 -0.9 2.6 2.0 0.2 1.8 0.9 0.1 0.6 1.1 1.6 1.9 1.7 -1.7 1.1
Alzheimer’s Disease (in mother) 0.5 0.6 1.6 0.0 -1.1 -0.3 -0.2 1.0 0.0 0.8 1.0 1.3 0.8 0.8 0.2 0.7 -0.8 -0.5
Alzheimer’s Disease (in father) 0.5 0.5 2.2 0.7 -0.3 0.2 -0.2 1.1 0.7 0.2 1.5 1.0 0.4 0.6 0.8 0.7 0.3 0.9
Alzheimer’s Disease (including proxy) 1.2 1.7 4.7 0.6 -1.6 -0.0 0.1 1.8 0.6 1.5 2.0 2.2 1.6 1.5 0.6 1.4 -1.1 0.4
Crohns Disease (2017) 0.3 0.6 1.8 0.8 -0.3 1.3 0.2 0.8 1.2 0.4 0.5 0.6 0.5 1.0 1.1 1.0 -0.5 0.9
Irritable Bowel Disease (IBD) 0.5 1.3 3.7 1.4 -0.6 1.9 0.5 0.4 1.4 0.8 1.0 0.8 0.8 1.4 1.5 1.3 -0.9 1.1
Ulcerative Colitis (UC) 0.3 0.5 1.6 1.0 -0.5 1.3 0.1 0.4 0.8 0.6 1.0 0.6 0.6 0.9 0.9 0.8 -0.5 0.5
Major Depression (MDD) 0.3 0.4 1.5 1.2 -0.3 1.0 0.5 0.2 0.7 0.5 0.4 0.4 0.4 0.5 0.7 0.7 -0.0 0.2
Reaction Time 0.1 0.1 0.4 -0.5 -0.1 -0.7 0.4 0.2 -0.1 -0.3 -0.4 0.3 0.5 -0.1 -0.3 -0.1 0.5 -0.1
Verbal and Numeric Reasoning (VNR) 0.2 0.5 1.8 0.9 0.6 0.6 -0.0 -1.0 1.2 -0.6 -0.5 -1.4 -0.5 0.1 0.9 0.1 -0.1 0.7
Breast Cancer 0.1 0.3 1.1 -0.5 -0.6 -1.0 0.0 0.3 -0.7 0.2 0.3 0.7 0.2 -0.0 -0.7 -0.1 -0.4 -0.9
Ovarian Cancer 0.7 0.9 3.4 1.8 -0.6 1.3 0.7 0.4 0.9 0.7 0.3 0.7 0.6 1.0 1.0 1.1 -1.2 -0.2
Prostate Cancer 1.5 2.1 6.4 -1.1 0.6 -1.6 -1.6 -0.3 -2.1 -1.3 -0.5 -0.5 -1.7 -1.5 -2.1 -1.5 1.1 -2.5
Age at First Birth 0.7 1.0 4.9 1.8 -0.4 0.8 -0.9 2.2 0.8 0.1 -0.1 1.5 0.3 0.8 1.1 1.0 -0.1 0.4
Bipolar Disorder (2011) 1.5 1.4 7.7 -0.6 2.4 0.2 -1.6 0.2 -0.3 0.0 0.0 0.0 0.0 -1.7 -0.5 -1.5 2.8 0.0
Body Mass Index (BMI) (2010) 0.1 0.2 0.6 -0.4 -0.1 -0.8 -0.7 -0.7 -0.3 0.0 0.5 -0.2 0.1 -0.1 -0.3 -0.2 -0.2 0.0
Coronary Artery Disease (CAD) 1.2 1.5 3.6 -0.4 1.9 -0.2 -1.7 -0.5 -0.3 -1.6 -1.8 0.0 -1.6 -1.2 -0.8 -1.0 1.9 0.0
Crohns Disease (2012) 1.8 2.9 6.5 1.5 -1.2 2.0 0.4 2.6 2.0 1.2 1.5 1.7 1.4 2.1 2.1 2.0 -0.8 1.8
Mean Putamen Volume 0.2 0.3 0.9 0.3 -0.4 0.2 -0.6 1.0 -0.0 0.3 0.9 1.0 0.3 0.3 -0.1 0.1 0.0 -0.7
Fasting Glucose 0.7 0.9 6.9 -0.9 -0.4 -1.1 -0.6 0.9 -2.6 0.2 -1.2 0.2 0.2 -0.4 -0.9 -0.5 -0.1 -0.2
HbA1C 0.4 0.4 1.6 -0.7 0.3 -1.3 0.2 -1.2 0.3 -0.5 0.1 -0.4 -0.7 -0.6 -0.8 -0.8 0.3 -0.4
HDL Cholesterol 0.6 1.0 1.9 -0.7 1.0 -1.1 -0.9 -1.4 -0.7 -0.9 -1.1 -0.9 -1.1 -1.2 -0.8 -1.0 0.8 -0.9
LDL Cholesterol 0.1 0.1 0.4 0.5 0.7 0.4 -0.4 -0.0 -0.1 -0.4 -0.1 -0.4 -0.4 -0.1 0.3 -0.1 0.5 0.2
Lupus 0.5 0.7 4.8 -1.0 -0.1 -1.1 0.8 -2.2 -0.8 0.3 -0.0 -0.8 0.2 -0.4 -0.8 -0.6 -0.5 0.0
Neuroticism (2016) 1.0 1.4 4.5 1.2 -0.4 1.5 0.5 2.1 1.7 0.4 0.7 1.4 0.6 1.3 1.5 1.3 0.0 1.2
Primary Biliary Cirrhosis 0.1 0.2 0.6 -0.8 0.3 -0.0 -0.5 0.5 0.1 -0.3 -0.3 -0.4 0.0 -0.2 0.1 -0.4 0.4 0.7
Rheumatoid Arthritis 0.6 0.8 2.2 1.2 -0.1 1.5 -0.1 -0.5 1.0 0.6 1.5 -0.2 0.3 0.8 1.1 1.1 -0.9 0.5
Schizophrenia (2014) 0.2 0.5 1.4 -1.1 1.2 0.0 -0.6 -0.3 0.9 -1.0 -0.8 0.0 0.0 -0.2 0.6 -0.4 0.8 0.0
Triglycerides 0.2 0.4 3.2 -0.5 -0.2 -0.7 0.2 0.2 -1.8 0.5 0.3 0.3 0.3 -0.2 -0.5 -0.6 0.3 -0.3
Type 2 Diabetes (T2D) (2012) 0.4 0.5 2.2 -0.4 0.8 -0.1 -1.5 0.7 -0.5 -0.7 -0.5 -0.5 -0.8 -0.6 -0.2 -0.5 1.0 0.0
Ulcerative Colitis 1.6 2.3 3.7 1.9 -1.2 1.4 0.1 1.6 1.8 1.0 1.5 1.7 1.4 1.9 1.8 1.9 -1.0 1.2
Blood Eosinophil Count 0.9 6.8 25.5 1.5 -2.4 2.2 1.0 2.2 2.0 2.8 5.0 3.0 2.7 2.9 2.2 2.8 -1.8 2.3
Blood Platelet Count 0.5 5.5 11.4 -3.2 1.0 -3.2 -1.6 -0.5 -3.2 -1.3 -1.6 -0.7 -1.7 -2.8 -3.4 -3.0 1.7 -3.2
Blood Red Count 1.7 16.9 33.9 -2.1 3.4 -3.0 -4.0 -3.2 -4.3 -4.3 -5.8 -3.6 -5.0 -4.6 -4.3 -4.6 3.0 -4.7
Blood White Count 0.4 2.9 5.4 -2.1 1.6 -1.6 -0.2 -1.0 -1.7 -1.5 -2.0 -1.6 -1.6 -2.1 -2.0 -2.3 2.0 -1.0
Heel T-Score 1.5 11.8 20.4 -3.0 3.4 -3.0 -4.5 -1.5 -2.7 -4.1 -4.5 -3.1 -4.2 -3.8 -2.9 -3.5 4.0 -1.9
BMI 0.1 0.7 3.9 0.4 -0.8 0.5 0.2 0.6 0.3 1.6 2.0 0.8 1.0 0.6 0.4 0.7 -0.9 0.0
Height 0.2 3.3 5.4 -2.3 1.7 -1.8 -2.1 -0.4 -1.4 -2.1 -2.0 -1.3 -1.8 -2.1 -1.6 -2.2 2.1 -1.3
Waist Hip Ratio (WHR) 0.2 1.1 3.2 -0.9 1.0 -0.7 -1.2 0.4 -1.0 -1.1 -0.9 -0.2 -1.2 -1.2 -1.1 -1.6 1.8 -0.3
Systolic Blood Pressure 0.1 0.6 2.4 -0.6 -0.4 -0.5 1.6 -0.6 -0.9 0.4 -1.1 -0.2 0.1 -0.3 -0.9 -0.6 -0.8 -1.1
Smoking Status 0.2 0.5 2.4 0.3 -0.7 0.2 1.5 -1.0 -0.2 1.2 0.6 0.3 0.7 0.3 -0.2 -0.1 -1.0 -0.2
Allergy or Eczema 0.4 1.1 3.3 0.6 -1.3 1.2 0.9 0.7 0.3 1.1 1.7 0.9 1.1 1.1 0.5 0.9 -1.8 -0.1
Cardiovascular Disease 0.0 0.1 0.7 0.1 -0.0 0.0 -0.3 -0.1 -0.8 0.1 0.4 -0.3 -0.4 -0.3 -0.5 -0.3 -0.1 -0.8
Hypothyroidism (self reported) 0.9 2.0 4.4 2.0 -0.9 2.1 1.2 0.7 1.6 0.9 0.7 0.7 1.3 1.6 1.8 1.7 -1.3 1.6
Respiratory disease 0.6 1.4 2.8 0.4 -1.6 -0.5 1.7 1.0 -0.3 1.7 1.5 1.7 1.4 1.0 -0.1 0.7 -1.6 -0.4
Type 2 Diabetes (T2D) (2018) 0.0 0.1 0.4 -0.1 0.2 0.3 -0.2 0.4 -0.2 0.0 0.4 0.1 -0.1 -0.2 -0.1 0.0 0.6 -0.0
Lung FEV1/FVC ratio 0.1 0.6 2.5 -0.7 -0.0 -0.7 -1.6 -0.8 -1.0 0.1 -0.6 -0.2 -0.3 -0.6 -0.9 -0.4 -0.3 -1.5
Lung FVC 0.4 2.0 6.2 -1.0 0.7 -1.4 -1.0 -0.5 -1.9 -1.1 -1.1 -0.6 -1.6 -1.6 -1.9 -1.7 0.8 -2.5
Neuroticism 0.4 1.0 3.9 1.8 -0.2 2.0 0.7 0.5 1.0 0.2 -0.7 0.5 0.3 0.8 1.2 1.0 -0.7 0.9
Chronotype (morning person) 0.4 1.0 5.3 -2.3 0.0 -1.4 -1.4 0.4 -0.1 0.1 0.9 0.6 0.6 -0.2 -0.3 -0.4 1.2 1.5
Hair Pigment 0.0 0.8 2.1 -0.5 -1.3 -0.5 1.4 0.5 -0.2 1.5 0.0 0.9 1.4 0.7 -0.2 0.3 -1.0 0.7
Tanning 0.0 0.2 1.0 -0.6 -0.5 -0.6 -0.1 0.6 -0.3 0.5 1.0 0.6 0.6 0.1 -0.3 0.2 -0.1 0.2
Hand grip strength (left) 0.1 0.4 1.9 -0.5 -0.2 -1.4 0.1 -0.2 -0.7 0.2 1.2 0.1 0.2 -0.3 -0.7 -0.6 0.1 -0.6
Number of treatments/medications taken 0.1 0.1 0.9 0.6 0.0 1.0 -0.1 0.0 0.2 0.2 -0.4 -0.1 -0.0 0.2 0.4 0.4 -0.3 0.1
Average weekly spirits intake 1.0 1.2 3.3 -0.1 -1.7 -0.3 1.0 0.3 0.1 1.6 1.8 0.9 1.4 1.2 0.3 0.8 -1.7 1.0
Sensitivity / hurt feelings 0.2 0.3 1.7 -0.1 0.6 0.8 0.2 -0.4 0.4 -0.3 -0.3 -0.3 -0.3 -0.1 0.4 -0.0 0.7 1.3
Frequency of depressed mood in last 2 weeks 0.9 1.3 5.2 2.0 0.1 2.3 0.2 0.2 1.9 0.3 -0.0 -0.3 0.2 1.0 1.8 1.2 -0.7 0.9
Hearing difficulty/problems: Yes 3.4 5.2 11.9 -0.8 3.0 -0.5 -3.4 -2.2 -0.7 -3.1 -2.3 -2.6 -3.1 -2.4 -1.0 -1.8 2.7 -1.5
Relative age of first facial hair 0.2 0.4 1.9 0.3 0.0 0.6 0.9 -1.1 0.8 0.2 -0.1 -0.4 0.2 0.3 0.4 0.4 -1.4 0.1
Other serious medical condition/disability diagnosed by doctor 0.1 0.2 0.6 -0.3 0.3 0.1 -0.4 -0.7 -0.0 -0.2 -0.6 -0.8 -0.3 -0.3 -0.2 -0.5 -0.1 0.3
Ever used hormone-replacement therapy (HRT) 5.1 6.5 15.3 2.7 -3.3 1.7 2.9 1.7 1.2 3.3 2.0 2.8 2.8 2.8 1.6 2.7 -3.9 -0.2
Ever had hysterectomy (womb removed) 0.3 0.3 1.2 0.1 -0.5 -0.1 1.1 -0.5 0.2 0.7 -0.1 0.1 0.8 0.5 0.3 0.2 -1.1 0.5
Systolic blood pressure, automated reading 0.1 0.2 0.7 -0.8 -0.1 -0.2 0.8 -0.3 -0.5 0.4 -0.3 -0.0 0.3 -0.1 -0.5 -0.2 -0.3 -0.1
Eye problems/disorders: Diabetes related eye disease 0.3 0.4 1.0 -0.4 0.4 -0.2 -0.1 -0.1 -0.9 -0.5 -1.0 -0.6 -0.6 -0.7 -0.8 -0.8 0.4 -0.3
Angina 1.4 1.9 2.9 -0.9 1.4 -1.1 -0.4 -1.5 -1.4 -1.2 -1.5 -1.5 -1.7 -1.7 -1.5 -1.5 1.4 -1.4
Medication for hormone replacement therapy 0.2 0.2 0.4 -0.6 -0.6 -0.6 0.2 0.4 -0.5 0.3 0.0 0.5 0.5 -0.0 -0.6 -0.1 -0.3 -0.4
Vitamin and mineral supplements 1.0 1.4 5.1 2.3 -0.6 2.1 -0.0 1.0 1.2 0.4 1.0 1.2 0.4 1.1 1.3 1.5 -0.9 0.1
Supplements: Zinc 0.7 0.7 1.8 -1.2 0.4 -1.3 1.0 -1.4 -0.9 -0.1 0.4 -0.7 -0.1 -0.8 -0.9 -1.0 0.2 -0.8
Medication: Co-codamol 1.7 1.9 3.2 1.6 -1.6 1.3 1.5 1.0 1.0 1.6 0.9 1.8 1.6 1.6 1.1 1.4 -1.8 0.2
Medication: Metformin 0.2 0.3 1.0 -0.7 0.7 0.0 0.4 -0.7 -0.0 -0.3 0.4 -0.5 -0.5 -0.3 0.0 -0.1 0.8 1.0
Diabetes (father) 0.9 1.2 2.7 -0.1 -1.6 -0.8 1.1 0.4 -1.0 1.5 1.5 1.4 0.9 0.5 -0.7 0.3 -1.5 -1.2
Diabetes (mother) 0.7 0.9 2.3 -0.6 1.3 -0.2 -1.5 -0.7 -0.4 -1.3 -0.8 -0.9 -1.1 -1.0 -0.4 -1.0 1.4 -0.2
Severe depression (siblings) 2.6 3.0 5.3 1.9 -1.1 1.6 2.2 0.6 2.2 1.5 0.9 0.9 1.6 2.1 2.2 2.3 -1.5 1.8
Pack years adult smoking proportion 2.0 3.0 7.4 -0.1 2.7 -0.0 -1.7 -2.4 0.1 -2.3 -1.4 -2.6 -2.3 -1.7 -0.2 -1.3 2.1 -0.5
Impedance of leg (right) 0.2 0.8 3.2 -0.9 0.6 -1.1 -0.6 0.3 -0.8 -1.3 -1.8 -0.5 -0.7 -0.9 -0.8 -0.8 1.0 -0.5
Leg fat-free mass (left) 0.1 0.6 1.8 -1.1 0.2 -1.3 -0.9 -0.3 -1.0 -0.1 0.4 -0.2 -0.3 -0.8 -1.1 -0.9 0.2 -1.1
Trunk fat percentage 0.2 0.7 2.8 0.1 -1.0 -0.1 -0.3 1.7 0.4 1.0 1.2 1.2 1.0 0.8 0.5 0.8 -0.6 0.7
Hand grip strength (right) 0.1 0.2 1.1 0.1 -0.1 -0.7 0.1 -0.2 -0.5 -0.1 0.8 -0.0 -0.2 -0.3 -0.5 -0.4 -0.3 -1.0
Townsend deprivation index at recruitment 0.8 1.2 4.6 -0.0 1.4 0.1 -1.0 0.0 -0.3 -1.4 -2.1 -1.1 -1.5 -1.1 -0.2 -0.6 1.6 -0.7
Current tobacco smoking 0.1 0.2 1.2 1.1 -0.2 0.7 0.6 -0.6 0.1 0.4 0.1 0.3 0.1 0.2 0.0 -0.2 -0.3 -0.6
Average weekly fortified wine intake 0.6 0.7 2.1 0.6 0.9 0.8 0.3 -1.4 1.3 -0.6 -0.7 -1.4 -0.1 0.2 1.0 0.1 -0.1 1.1
Maternal smoking around birth 0.6 0.8 5.1 0.4 0.2 -0.3 -1.6 0.5 -1.1 -0.3 -0.5 -0.3 -0.8 -0.7 -1.0 -0.6 0.4 -2.3
Fed-up feelings 0.1 0.2 1.0 0.8 0.5 1.0 -0.2 -0.3 0.4 -0.3 -0.4 -0.4 -0.4 -0.0 0.5 0.2 0.3 0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.2 2.8 0.9 1.7 1.1 -1.1 -1.2 0.2 -1.4 -1.1 -1.6 -1.6 -0.8 0.1 -0.6 0.9 -0.2
Relative age voice broke 0.1 0.2 1.1 -0.8 0.2 -0.3 0.3 -0.7 0.4 -0.2 0.3 -0.6 -0.0 0.1 0.1 -0.1 -0.3 1.0
Taking other prescription medications 1.7 2.7 5.6 2.1 -0.7 2.4 1.3 1.0 2.3 0.9 0.7 0.7 1.1 1.9 2.2 2.0 -1.5 1.9
Age when periods started (menarche) 0.4 1.0 4.4 -0.5 0.7 -0.7 -0.1 -0.7 -1.1 -0.7 -2.1 -0.3 -0.7 -1.0 -1.1 -1.1 1.1 -1.1
Bilateral oophorectomy (both ovaries removed) 0.9 1.0 3.0 -0.5 0.3 -1.7 -1.1 -0.3 -1.3 -0.9 -0.9 -0.2 -0.6 -1.1 -1.3 -1.2 0.4 -1.5
Heel bone mineral density (BMD) T-score, automated (left) 1.1 2.4 6.7 -1.6 0.5 -2.6 -1.3 -1.0 -2.1 -1.1 -1.2 -0.7 -1.5 -1.6 -2.1 -1.6 0.7 -2.1
Tinnitus: Yes, but not now, but have in the past 1.0 1.1 2.1 -1.1 1.1 -1.5 -1.3 -0.9 -0.8 -1.3 -0.7 -0.9 -0.9 -1.1 -1.0 -1.2 1.1 -0.6
Qualifications: CSEs or equivalent 0.7 1.0 2.4 0.5 -1.5 -0.4 0.5 1.6 -0.1 1.4 -0.1 1.4 1.3 0.8 0.1 0.8 -1.3 -0.8
Serious illness, injury or assault to yourself 1.8 2.2 4.1 -1.0 1.8 -0.2 -1.3 -1.4 -1.1 -1.5 -1.8 -2.0 -1.8 -1.9 -1.0 -1.9 1.4 -1.1
High blood pressure 0.5 1.4 2.7 1.5 -0.6 1.6 1.4 0.0 1.2 1.0 1.3 0.2 0.9 1.2 1.4 1.1 -1.5 1.1
Hayfever, allergic rhinitis or eczema 1.2 2.5 5.9 0.8 -1.8 1.7 1.1 1.5 0.8 1.8 2.4 1.6 1.8 1.8 1.1 1.6 -1.8 1.2
Multivitamins +/- minerals 2.3 2.9 5.6 -2.4 1.7 -1.8 -1.7 -1.0 -1.4 -1.7 -1.4 -1.8 -1.6 -2.0 -1.6 -2.1 2.0 -0.7
Stomach or abdominal pain in last month 1.6 2.0 5.5 2.3 -1.3 2.1 1.2 0.5 1.3 1.2 0.7 0.7 1.2 1.6 1.4 1.6 -2.1 0.2
Supplements: Glucosamine 0.4 0.5 3.0 -1.6 -0.3 -1.7 0.3 0.1 -0.8 0.4 0.5 0.1 0.5 -0.3 -0.6 -0.2 0.2 0.4
Diverticular disease/diverticulitis (self-reported) 0.4 0.4 2.2 1.4 0.1 1.5 -0.4 0.1 0.8 -0.1 0.4 -0.2 -0.1 0.4 0.9 0.5 -0.3 0.5
Medication: Atenolol 0.3 0.3 1.7 -1.0 -0.4 -0.9 0.9 -0.4 -0.2 0.2 0.2 -0.2 0.4 0.2 -0.1 0.0 -0.5 1.3
Medication: Levothyroxine sodium 1.2 2.0 5.5 2.1 -0.4 2.3 1.3 -0.1 2.0 0.6 0.9 -0.1 0.8 1.5 1.9 1.6 -1.1 1.6
Sitting height 0.0 0.2 0.6 0.0 0.6 -0.2 -0.7 0.2 0.8 -0.8 -0.6 -0.2 -0.2 -0.1 0.4 -0.3 0.6 0.3
Chronic bronchitis/emphysema (father) 1.8 2.1 4.3 -2.1 1.4 -1.7 -1.1 -1.0 -1.5 -1.4 -1.5 -1.4 -1.3 -1.8 -1.5 -1.6 1.5 -0.9
High blood pressure (mother) 0.3 0.4 0.9 0.9 -0.3 0.8 0.5 0.2 0.5 0.3 -0.8 0.2 0.4 0.5 0.8 0.6 -0.9 -0.2
Body mass index (BMI) 0.0 0.2 1.2 -0.3 -0.3 -0.2 -0.4 0.1 -0.2 0.8 1.1 0.1 0.4 0.1 0.0 0.3 -0.5 0.2
Impedance of leg (left) 0.1 0.6 2.2 -0.9 0.5 -1.0 -0.3 0.2 -0.5 -1.1 -1.5 -0.3 -0.5 -0.7 -0.6 -0.8 1.0 0.0
Leg predicted mass (left) 0.1 0.6 1.7 -1.1 0.1 -1.3 -0.9 -0.2 -1.1 -0.1 0.4 -0.2 -0.3 -0.8 -1.1 -0.9 0.2 -1.1
Trunk fat mass 0.1 0.3 1.6 -0.3 -0.6 -0.5 -0.6 1.2 0.0 0.6 0.8 0.8 0.6 0.3 0.1 0.4 -0.3 0.3
Waist circumference 0.0 0.1 0.6 -0.4 -0.2 -0.3 -0.5 0.4 -0.3 0.5 0.7 0.3 0.1 -0.0 -0.1 -0.1 -0.2 0.2
Number of incorrect matches in round 0.6 1.0 3.2 -1.0 -1.1 0.1 0.0 1.0 0.2 1.2 1.4 1.4 1.2 1.0 0.2 0.7 -0.1 1.8
Past tobacco smoking 0.3 0.6 1.5 0.8 1.1 0.7 -0.8 -0.2 0.3 -1.2 -0.8 -1.0 -1.0 -0.6 0.2 -0.3 0.9 -0.4
Alcohol usually taken with meals 0.3 0.4 1.5 -0.0 -1.0 -0.6 0.9 1.2 -0.6 0.5 -0.2 0.7 0.9 0.4 -0.2 0.4 -0.5 -0.4
Nervous feelings 0.5 1.0 3.3 1.8 -1.0 1.2 1.1 0.2 0.5 1.1 -0.3 0.9 0.7 1.0 0.7 1.0 -1.5 0.1
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 2.1 0.0 1.0 0.4 -0.5 -0.6 0.5 -0.9 -1.4 -1.3 -0.9 -0.4 0.1 -0.7 0.8 0.5
Hearing difficulty/problems with background noise 0.8 1.3 5.7 -1.0 1.4 -0.7 -2.4 -0.6 -0.6 -1.6 -0.4 -0.9 -1.2 -1.2 -0.5 -0.7 1.8 -0.2
Hair/balding pattern: Pattern 2 0.2 0.2 1.5 -0.2 -0.0 0.1 1.2 -0.3 0.1 0.6 0.7 -0.1 0.7 -0.1 0.2 0.2 0.1 0.5
Had menopause 4.9 6.1 10.6 2.5 -2.7 2.2 2.4 1.9 2.3 2.7 1.4 2.3 2.8 3.1 2.3 2.8 -3.3 1.6
Had other major operations 1.3 1.6 4.4 -0.4 2.0 0.2 -0.9 -2.1 0.4 -1.6 -1.6 -1.9 -1.4 -0.9 0.4 -0.5 1.1 1.3
Forced vital capacity (FVC) 0.4 1.5 4.2 -1.0 0.7 -1.3 -0.7 -0.1 -1.2 -1.2 -1.3 -0.7 -1.2 -1.4 -1.5 -1.7 0.8 -2.0
Heel bone mineral density (BMD) T-score, automated (right) 1.1 2.4 6.0 -1.7 0.7 -2.4 -1.5 -1.1 -1.9 -1.3 -1.2 -0.9 -1.6 -1.7 -2.0 -1.6 0.8 -1.8
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 1.2 0.9 0.2 1.1 -0.1 -0.7 0.4 -0.1 -0.9 -0.7 -0.4 0.2 0.5 0.3 -0.7 -0.2
Qualifications: None of the above 0.3 0.6 1.3 0.6 1.1 1.1 -0.3 -1.1 0.8 -0.7 -1.1 -0.7 -0.5 -0.1 0.8 -0.1 0.3 0.8
Financial difficulties in last 2 years 1.1 1.5 4.5 1.5 1.5 1.7 0.2 -2.1 1.1 -1.3 -1.1 -2.1 -0.9 -0.3 0.9 0.0 -0.0 -0.1
Mouth/teeth dental problems 0.5 0.7 2.9 -0.6 -1.3 -1.0 0.6 1.7 -0.5 0.9 0.3 1.4 0.8 0.4 -0.5 0.3 -0.4 -0.3
Heart attack 0.6 0.8 1.7 -0.7 0.8 -0.5 -1.3 -0.7 -0.8 -1.0 -1.2 -1.0 -1.2 -1.0 -0.7 -0.5 0.7 -0.3
Allergy 1.5 3.5 6.5 -1.0 2.4 -1.2 -2.0 -1.6 -0.7 -2.5 -2.4 -2.0 -2.4 -2.0 -1.0 -1.7 2.5 -1.0
Pain all over the body in last month 0.7 0.7 2.2 1.1 0.7 1.4 -0.3 -0.1 1.5 -0.4 -0.3 -0.5 -0.2 0.4 1.3 0.6 0.4 1.2
Diabetes (self-reported) 0.2 0.2 0.9 -0.2 0.6 0.3 -1.0 0.1 -0.2 -0.5 -0.4 -0.4 -0.8 -0.5 -0.2 -0.4 0.7 -0.1
Hayfever/allergic rhinitis (self-reported) 0.3 0.5 2.9 0.1 0.4 -0.0 -1.7 0.3 -0.8 -0.5 0.1 -0.1 -0.8 -0.4 -0.6 -0.2 0.8 -0.9
Medication: Ramipril 0.3 0.4 2.2 0.7 0.3 0.4 0.5 -1.5 -0.4 -0.3 0.1 -0.9 -0.8 -0.4 -0.3 -0.4 -0.3 -0.8
Medication: Simvastatin 0.1 0.2 0.5 0.0 -0.1 0.4 -0.5 0.7 -0.6 0.2 0.7 0.5 -0.4 -0.2 -0.4 -0.1 0.3 -0.3
Fluid intelligence score 0.2 0.4 1.4 0.8 0.2 0.6 0.4 -0.4 1.2 -0.1 -0.4 -0.6 -0.0 0.4 1.0 0.4 -0.4 0.8
Illnesses of siblings 0.3 0.4 0.9 -0.9 0.0 -0.7 0.5 0.3 -0.9 -0.2 0.5 0.5 -0.3 -0.5 -0.8 -0.6 0.9 -0.6
Neuroticism score 0.3 0.7 2.4 1.6 -0.5 1.5 0.8 0.7 0.5 0.6 -0.5 0.5 0.3 0.7 0.7 0.9 -0.7 0.7
Weight 0.0 0.2 0.8 -0.8 -0.0 -0.9 -0.8 0.2 -0.5 0.2 0.5 -0.0 0.0 -0.3 -0.4 -0.3 -0.0 -0.3
Impedance of arm (right) 0.3 1.3 3.2 1.2 -1.2 0.7 1.3 1.8 1.1 0.7 0.1 1.6 1.1 1.3 1.1 1.2 -0.7 0.8
Arm fat percentage (right) 0.1 0.5 1.7 -0.0 -1.1 -0.2 0.3 0.8 -0.1 1.3 1.1 0.8 0.9 0.6 0.1 0.7 -1.0 0.3
Trunk fat-free mass 0.2 1.1 2.8 -1.7 0.5 -1.6 -1.0 -0.8 -1.3 -0.4 -0.2 -0.8 -0.6 -1.2 -1.3 -1.3 0.4 -1.0
Hip circumference 0.1 0.3 1.0 -0.2 -0.7 -0.6 -0.3 0.1 -0.4 0.9 0.9 0.4 0.5 0.2 -0.3 0.1 -1.0 -0.5
Time employed in main current job 1.3 1.5 5.0 1.3 0.1 1.8 1.0 0.6 2.2 0.2 -0.3 -0.1 0.5 1.1 2.0 1.2 -0.4 2.2
Alcohol intake versus 10 years previously 2.7 4.0 6.4 -2.5 1.6 -2.1 -1.7 -0.6 -2.1 -2.0 -2.1 -1.3 -2.2 -2.3 -2.2 -2.4 2.4 -1.6
Father’s age at death 1.1 1.5 2.5 1.0 -1.1 1.2 0.6 0.7 1.6 1.2 0.7 0.9 1.3 1.6 1.5 1.5 -1.5 1.5
Worrier / anxious feelings 0.2 0.4 1.3 0.7 0.3 0.9 0.6 0.7 0.9 -0.3 -0.1 0.3 -0.0 0.3 0.7 0.1 0.6 1.2
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 2.7 1.4 0.5 1.6 -0.2 0.1 1.3 -0.2 -0.7 -0.5 -0.3 0.5 1.3 0.7 -0.1 0.9
Falls in the last year 0.9 1.2 7.1 0.0 -0.2 1.2 0.5 1.0 1.7 0.5 0.7 0.5 1.3 1.0 1.3 0.6 0.5 2.7
Hair/balding pattern: Pattern 3 2.1 3.2 6.2 -1.4 2.2 -0.9 -2.5 -1.4 -0.9 -2.4 -1.6 -2.0 -2.2 -2.0 -1.1 -1.6 2.4 -0.3
Number of live births 0.4 0.6 2.2 -0.3 1.1 0.8 -0.4 -0.7 0.5 -0.6 -0.2 -1.5 -0.4 -0.4 0.1 -0.5 1.0 1.0
Forced expiratory volume in 1-second (FEV1) 0.5 1.6 6.4 -1.1 0.3 -1.7 -0.7 -0.2 -1.7 -0.9 -1.3 -0.4 -0.9 -1.3 -1.7 -1.5 0.4 -2.5
Pulse rate 1.9 3.3 7.9 -1.9 2.4 -1.2 -1.0 -1.9 -0.9 -2.0 -1.8 -1.9 -1.8 -2.2 -1.2 -2.1 2.8 0.2
Happiness 0.3 0.3 1.1 0.4 0.8 0.9 -0.0 -0.5 0.3 -1.0 -0.3 -0.7 -0.9 -0.3 0.2 -0.1 0.6 0.4
Noisy workplace 1.1 1.3 1.8 -1.3 1.1 -1.3 -1.2 -1.3 -0.8 -1.3 -0.8 -1.1 -1.3 -1.3 -1.0 -1.3 1.0 -0.8
Qualifications: A levels/AS levels or equivalent 0.3 0.6 2.1 0.3 0.8 -0.4 -0.2 -1.3 0.0 -1.1 -1.1 -1.4 -0.7 -0.6 -0.1 -0.6 0.3 0.2
Serious illness, injury or assault of a close relative in last 2 years 1.1 1.2 2.8 -1.1 1.2 -0.5 -0.2 -1.2 -0.7 -1.0 -1.5 -1.7 -1.0 -1.3 -0.9 -1.5 0.8 -0.8
Mouth/teeth dental problems: Dentures 0.6 1.1 3.9 -0.1 1.6 0.5 -0.3 -2.0 -0.0 -1.1 -1.1 -1.5 -1.2 -1.1 -0.2 -0.9 1.0 0.2
Asthma 0.3 0.6 2.8 -0.2 -0.9 -0.6 1.7 0.2 -0.1 1.1 1.1 0.7 1.0 0.7 -0.1 0.3 -0.9 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 3.0 -0.2 -0.3 0.2 1.3 0.2 0.9 0.6 0.7 0.4 0.8 0.7 0.9 1.0 0.0 1.7
Medication: Cholesterol lowering 0.4 0.6 2.8 -0.3 0.3 -0.0 -1.7 1.0 -0.9 -0.4 -0.0 0.2 -0.9 -0.6 -0.7 -0.6 1.0 -0.7
Depression (self-reported) 0.4 0.5 2.5 1.6 0.0 1.0 -0.8 0.8 0.6 -0.2 -0.5 0.1 -0.3 0.2 0.6 0.4 -0.3 -0.7
Medication: Lansoprazole 0.3 0.4 0.9 0.9 -0.0 0.8 0.0 0.8 0.9 -0.0 -0.8 -0.1 0.3 0.5 0.9 0.4 -0.4 0.8
Prospective memory result 0.5 0.6 1.6 -0.6 -0.9 -1.0 0.3 1.3 -1.1 0.4 1.0 0.9 0.5 0.1 -0.9 -0.2 -0.1 -0.6
Lung cancer (father) 1.3 1.6 2.9 -1.7 1.1 -1.1 -1.6 -1.1 -1.2 -1.2 -1.0 -0.8 -1.1 -1.4 -1.3 -1.5 1.3 -1.0
Illnesses of mother 0.2 0.2 1.4 -0.1 -0.0 -0.1 -0.7 0.8 0.3 -0.1 1.2 0.7 -0.0 0.0 0.1 0.0 0.4 0.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.5 5.6 -0.9 0.4 -1.4 -0.7 -0.4 -1.6 -1.0 -1.6 -0.6 -0.9 -1.3 -1.6 -1.4 0.3 -2.4
Pulse wave Arterial Stiffness index 0.4 0.5 2.3 1.0 0.4 1.5 0.9 -0.1 0.8 0.2 -0.8 -0.8 -0.0 0.2 0.7 0.5 -0.2 0.5
Impedance of arm (left) 0.3 1.5 4.2 1.2 -1.3 0.9 1.2 2.1 1.1 0.7 0.3 1.9 1.2 1.4 1.1 1.2 -0.6 0.6
Arm fat mass (right) 0.1 0.4 1.3 -0.4 -0.9 -0.7 0.2 0.4 -0.4 1.1 1.1 0.5 0.7 0.3 -0.3 0.3 -0.9 -0.1
Trunk predicted mass 0.2 1.1 3.1 -1.8 0.5 -1.7 -0.9 -0.7 -1.4 -0.4 -0.2 -0.7 -0.5 -1.2 -1.4 -1.4 0.5 -1.0
Standing height 0.2 1.6 4.0 -1.7 0.8 -2.0 -1.1 0.3 -1.1 -1.3 -1.1 -0.3 -0.8 -1.4 -1.5 -1.7 1.3 -1.2
Length of working week for main job 0.3 0.3 1.3 0.0 -0.6 -0.1 1.1 0.0 0.5 0.4 -0.3 0.4 0.6 0.5 0.5 0.5 -1.1 0.2
Exposure to tobacco smoke at home 1.1 1.2 2.8 0.6 1.6 1.1 -1.4 -1.1 1.4 -1.0 -0.7 -1.7 -1.0 -0.2 1.1 0.1 0.7 1.3
Breastfed as a baby 1.4 1.8 5.7 1.1 1.2 2.4 1.0 -0.8 2.3 -0.5 0.2 -1.2 0.1 0.7 2.1 1.0 0.2 2.0
Tense / ‘highly strung’ 0.4 0.6 1.8 1.3 0.3 1.3 0.6 -0.4 1.2 -0.2 -0.9 -0.1 0.2 0.5 1.1 0.7 -0.4 0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 1.6 1.2 0.9 1.3 -1.0 0.2 1.2 -0.9 -0.1 -0.7 -0.8 0.0 1.0 0.0 0.6 0.6
Hair/balding pattern: Pattern 4 0.5 1.1 2.3 1.5 -0.8 1.3 1.1 0.6 1.3 0.9 -0.3 0.7 1.0 1.3 1.2 1.0 -1.3 0.8
Birth weight of first child 0.9 1.6 4.5 0.9 -1.0 1.2 0.4 2.1 1.3 1.1 1.6 1.5 1.1 1.3 1.2 1.5 -0.1 1.4
Peak expiratory flow (PEF) 0.4 1.0 4.3 -1.2 -0.2 -2.1 -0.7 -0.0 -1.5 -0.3 -0.1 0.0 -0.2 -0.8 -1.4 -0.8 -0.2 -1.7
Pulse wave reflection index 1.0 1.2 2.7 1.6 -1.1 1.4 1.2 1.1 0.4 1.3 0.6 0.5 1.0 1.1 0.8 1.3 -1.6 -0.5
Ever highly irritable/argumentative for 2 days 0.4 0.5 1.7 -1.1 -0.1 -1.3 0.1 -1.3 -1.1 -0.0 0.0 -0.3 -0.2 -0.5 -1.0 -0.7 -0.2 -0.4
Loud music exposure frequency 1.4 1.5 4.6 2.2 0.0 2.1 1.0 -1.1 1.6 0.6 1.5 -0.1 0.2 0.9 1.5 1.0 -1.3 0.5
Qualifications: O levels/GCSEs or equivalent 0.7 1.2 4.1 0.4 -1.7 -0.1 1.0 2.0 -0.3 1.5 0.8 1.4 1.3 0.9 -0.1 0.9 -1.0 -0.6
Mouth/teeth dental problems: Bleeding gums 0.3 0.3 0.8 0.1 0.7 0.4 -0.9 -0.7 -0.2 -0.6 0.3 -0.8 -0.8 -0.5 -0.3 -0.4 0.4 -0.8
Blood clot in the leg (DVT) 0.5 0.6 2.0 1.4 -0.5 1.0 1.2 0.2 0.7 0.7 -0.1 0.1 0.7 0.5 0.8 0.8 -1.2 -0.4
Medication: Paracetamol 0.3 0.5 1.7 -0.5 1.0 -0.4 0.5 -1.1 0.3 -0.6 -1.3 -1.0 -0.2 -0.6 0.1 -0.4 0.8 0.8
Headache pain in last month 0.1 0.2 1.0 1.0 0.3 0.2 -0.1 -0.2 0.8 -0.3 -0.7 -0.2 0.2 0.2 0.7 0.4 0.2 0.8
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 1.1 -0.1 0.5 -0.2 1.1 -1.1 0.6 -0.4 -0.8 -0.8 0.1 -0.0 0.3 0.1 -0.3 0.3
Glaucoma (self-reported) 0.6 0.7 2.9 0.4 -0.3 0.6 1.3 0.0 1.1 0.5 0.7 0.3 0.7 0.8 1.0 0.7 -0.3 1.7
Gout (self-reported) 1.3 1.8 4.7 0.1 2.2 0.8 -0.5 -1.9 0.5 -1.7 -1.3 -2.1 -1.6 -1.0 0.3 -0.8 1.8 1.0
Hypothyroidism/myxoedema (self-reported) 1.0 1.9 4.9 1.8 -0.4 2.2 0.4 0.8 2.0 0.4 0.9 0.4 0.9 1.6 2.0 1.7 -0.7 2.0
Medication: Amlodipine 0.2 0.3 0.9 0.3 -0.3 0.8 -0.7 0.9 0.3 0.3 0.9 0.5 0.3 0.4 0.5 0.5 0.1 0.6
Medication: Ventolin 100micrograms inhaler 1.2 1.5 6.1 -1.8 -0.2 -2.5 -0.5 -0.2 -1.9 -0.1 -0.0 -0.1 -0.3 -0.9 -2.0 -1.5 0.3 -1.6
Birth weight 0.8 1.8 3.1 1.3 -1.0 1.2 1.2 -0.1 1.7 1.2 1.3 0.7 1.4 1.8 1.6 1.5 -1.6 1.6
Chronic bronchitis/emphysema (mother) 0.2 0.2 1.1 -0.3 -0.5 -0.5 -0.0 0.7 -0.3 0.5 -1.0 0.3 0.6 0.3 -0.1 0.4 -0.0 0.2
High blood pressure (siblings) 0.6 0.9 2.9 0.6 1.2 0.7 -1.7 -1.1 1.2 -1.0 -0.8 -1.5 -0.7 -0.2 0.8 -0.2 0.3 0.8
Forced vital capacity (FVC), Best measure 0.3 0.9 3.1 -0.6 0.5 -0.9 -0.5 -0.1 -1.0 -1.0 -1.3 -0.5 -0.8 -1.0 -1.2 -1.3 0.5 -1.8
Body fat percentage 0.1 0.3 1.3 -0.1 -0.7 -0.3 -0.5 1.1 0.0 0.7 0.8 0.6 0.6 0.4 0.2 0.5 -0.5 0.4
Leg fat percentage (right) 0.1 0.4 1.6 -0.8 0.5 -0.7 -1.3 0.1 -0.7 -0.4 -0.4 -0.7 -0.6 -0.7 -0.5 -0.4 0.4 -0.3
Arm fat-free mass (right) 0.1 0.6 1.9 -1.3 0.2 -1.4 -0.8 -0.5 -0.9 0.0 0.4 -0.3 -0.2 -0.8 -1.0 -0.9 0.2 -0.7
Exposure to tobacco smoke outside home 0.2 0.3 0.8 -0.0 -0.7 -0.9 0.2 0.6 -0.2 0.7 0.2 0.9 0.9 0.1 -0.2 -0.0 -0.2 -0.5
Comparative body size at age 10 0.1 0.2 0.6 -0.1 -0.1 -0.5 0.7 -0.7 -0.2 0.4 -0.4 -0.2 0.1 -0.0 -0.1 -0.1 -0.5 -0.5
Number of full brothers 0.2 0.2 1.1 0.2 0.3 -0.1 -1.0 -0.0 -0.3 -0.4 -1.0 -0.4 -0.5 -0.4 -0.2 -0.1 0.3 -0.3
Worry too long after embarrassment 0.9 1.5 3.7 -0.4 -1.9 -0.5 1.9 0.7 -0.2 1.7 1.2 1.7 1.5 1.2 0.0 0.8 -1.5 1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 0.9 3.1 1.3 0.9 1.8 -0.9 0.2 1.4 -0.9 -0.6 -0.6 -0.5 0.2 1.4 0.5 0.4 1.0
Wheeze or whistling in the chest in last year 0.0 0.1 0.3 0.1 -0.1 0.5 0.5 -0.1 0.3 0.4 0.2 -0.0 0.1 0.2 0.0 -0.0 -0.1 0.5
Number of children fathered 0.4 0.4 1.8 0.5 0.9 0.8 -1.4 0.1 0.7 -0.7 -0.1 -0.8 -0.5 -0.1 0.5 -0.2 0.9 0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 0.9 0.5 -0.1 0.6 0.7 0.6 0.4 0.3 1.0 0.2 0.2 0.3 0.4 0.1 0.1 0.4
Age at first live birth 0.3 0.5 1.9 0.5 -0.7 -0.4 0.1 1.2 -0.5 0.2 1.2 1.4 0.3 0.2 -0.2 0.0 -0.2 -0.8
Pulse wave peak to peak time 0.4 0.4 2.2 -1.0 -0.4 -1.5 -0.9 0.1 -0.6 -0.2 0.8 0.8 0.0 -0.1 -0.7 -0.5 0.3 -0.3
Health satisfaction 0.0 0.0 0.1 -0.1 -0.1 -0.1 -0.1 0.4 -0.0 0.2 0.3 0.3 0.2 0.1 0.1 0.2 -0.0 0.3
Shortness of breath walking on level ground 2.2 2.6 4.5 -0.5 1.9 -0.1 -1.9 -1.1 -1.3 -1.8 -1.3 -1.8 -2.0 -1.9 -1.3 -1.7 1.7 -2.1
Qualifications: College or University degree 0.1 0.4 2.3 1.5 0.6 0.8 -0.4 -0.2 0.9 -0.5 0.4 -0.2 -0.5 -0.0 0.7 0.1 0.3 -0.0
Eye problems/disorders: None of the above 0.2 0.3 1.5 -0.4 0.2 -0.6 -1.2 0.3 -0.4 -0.2 0.6 0.2 -0.5 -0.4 -0.2 -0.0 0.7 -0.6
Mouth/teeth dental problems: Loose teeth 0.8 0.9 2.7 0.4 1.6 1.0 -0.4 -1.1 0.6 -1.3 -0.3 -1.5 -1.2 -0.8 0.2 -0.7 1.0 -0.0
Emphysema/chronic bronchitis 2.2 2.4 3.9 1.8 -1.4 1.3 1.5 1.0 1.4 1.9 1.4 1.4 2.0 1.8 1.6 1.8 -1.6 1.3
Medication for pain relief, constipation, heartburn 0.3 0.4 1.4 -0.2 0.4 -0.4 -0.9 -0.2 -0.8 -0.7 -0.4 -0.3 -0.8 -0.6 -0.8 -0.8 0.5 -1.2
Neck or shoulder pain in last month 0.6 0.9 2.5 1.6 -0.5 1.5 0.5 1.1 0.8 0.6 -0.3 0.5 0.8 1.0 1.0 1.2 -0.9 0.3
Medication: Blood pressure 1.0 1.8 4.0 1.6 -1.0 2.0 0.4 1.1 1.3 1.4 1.9 1.1 1.0 1.4 1.4 1.4 -1.0 1.1
Angina (self-reported) 1.5 2.0 3.1 -1.2 1.2 -1.2 -0.4 -1.4 -1.6 -1.2 -1.4 -1.4 -1.7 -1.8 -1.7 -1.7 1.4 -1.4
Migraine (self-reported) 0.9 1.1 2.1 0.9 -1.1 0.7 1.4 0.6 0.9 1.3 0.8 1.0 1.5 1.3 1.0 1.2 -1.1 0.6
Medication: Ibuprofen 0.5 0.5 2.5 -0.1 -0.2 0.4 0.5 0.5 0.9 0.4 1.0 0.6 0.6 0.6 0.9 0.9 0.4 1.6
Medication: Allopurinol 0.8 1.1 2.2 -0.3 1.3 -0.5 -1.1 -1.0 -0.7 -1.4 -1.1 -1.1 -1.5 -1.2 -0.7 -1.3 1.4 -0.3
Medication: Omeprazole 0.0 0.1 0.4 -0.0 0.1 0.2 -0.3 0.6 -0.1 -0.1 -0.3 0.2 0.0 -0.0 -0.0 0.0 0.3 0.1
Medication: Seretide 50 evohaler 0.4 0.4 2.2 -1.5 0.3 -1.3 0.4 0.3 -0.3 -0.2 -0.7 -0.7 0.1 -0.5 -0.5 -0.6 0.7 0.3
Mean time to correctly identify matches 0.2 0.3 1.5 -0.0 -0.1 0.5 0.6 0.4 0.9 0.2 -0.2 0.3 0.7 0.5 0.7 0.5 0.1 1.2
Heart disease (mother) 2.0 2.4 5.0 0.9 -1.6 0.5 2.2 0.1 1.3 1.8 0.9 0.8 2.2 1.9 1.4 1.7 -2.1 1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 2.5 -1.6 0.7 -1.4 -0.2 0.1 -0.8 -0.6 0.3 -0.1 -0.4 -0.9 -1.0 -0.8 1.4 0.1
Whole body fat mass 0.0 0.2 0.5 -0.4 -0.3 -0.6 -0.7 0.7 -0.3 0.5 0.7 0.3 0.3 -0.0 -0.2 0.0 -0.2 -0.1
Leg fat mass (right) 0.2 0.8 2.2 -1.4 0.5 -1.5 -1.4 -0.3 -1.2 -0.4 -0.1 -0.6 -0.6 -1.0 -1.0 -0.8 0.5 -0.7
Arm predicted mass (right) 0.3 1.3 3.2 -1.7 0.7 -1.8 -1.3 -0.9 -1.3 -0.5 -0.1 -0.8 -0.7 -1.3 -1.4 -1.4 0.6 -1.1
Pulse rate, automated reading 0.3 1.1 2.7 0.9 -0.4 1.6 1.6 0.7 1.4 1.0 -0.1 0.7 0.9 0.9 1.2 0.7 -0.4 1.4
Alcohol intake frequency. 0.5 1.2 3.4 -0.8 0.9 -0.8 -0.2 -1.5 -1.0 -0.8 -1.8 -1.5 -1.0 -1.2 -1.1 -1.2 0.8 -0.9
Comparative height size at age 10 0.1 0.5 1.4 -0.8 0.2 -1.1 -0.7 0.9 -0.6 -0.7 -0.1 0.1 -0.5 -0.6 -0.8 -0.8 0.7 -1.2
Number of full sisters 0.3 0.4 1.6 0.2 -0.1 0.9 -0.9 1.2 0.6 0.4 0.2 0.5 0.4 0.4 0.5 0.4 0.3 0.5
Suffer from ‘nerves’ 0.7 1.1 2.9 1.7 -0.9 1.4 0.8 0.6 1.0 0.9 -0.3 0.6 0.9 1.2 1.1 1.3 -1.3 0.9
Overall health rating 0.4 0.9 2.8 1.1 0.8 1.7 -1.4 0.4 1.4 -0.3 0.2 -0.3 -0.2 0.3 1.4 0.5 0.5 1.1
Chest pain or discomfort 0.6 0.9 2.2 1.0 -0.8 0.9 0.4 1.5 0.8 1.0 1.1 0.9 1.0 1.0 0.9 1.0 -0.6 0.6
Had major operations 0.0 0.0 0.1 0.3 -0.2 -0.1 -0.0 0.3 0.2 0.1 0.1 0.0 0.1 0.1 0.2 0.2 -0.1 0.0
Age at last live birth 0.2 0.2 0.7 0.3 0.7 0.1 -0.6 -0.4 -0.2 -0.8 0.0 -0.4 -0.6 -0.5 -0.1 -0.5 0.5 -0.6
Family relationship satisfaction 0.2 0.3 1.0 -0.6 0.7 0.2 0.1 -1.0 -0.2 -0.7 -0.0 -0.8 -0.8 -0.5 -0.3 -0.7 0.3 0.3
Leg pain on walking 0.2 0.3 1.0 0.1 -0.1 0.7 1.0 -0.8 0.4 0.4 -0.0 -0.0 0.4 0.4 0.6 0.6 -0.3 0.6
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.1 -0.7 -0.9 -0.7 0.5 0.6 -0.4 1.0 -0.1 0.3 0.9 0.4 -0.3 0.2 -0.4 0.6
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.7 0.7 -0.3 0.8 0.2 0.6 0.6 0.2 -0.4 0.3 0.4 0.5 0.7 0.6 -0.2 0.4
Illness, injury, bereavement, stress in last 2 years 0.6 0.8 2.7 0.0 -1.3 -0.9 0.2 1.7 -0.3 0.9 1.0 1.6 0.8 0.8 -0.1 0.9 -0.3 0.1
Medication: Aspirin 1.6 2.1 3.6 -1.1 1.4 -1.1 -1.6 -1.0 -1.7 -1.1 -0.9 -1.3 -1.7 -1.9 -1.8 -1.8 1.5 -1.5
Supplements: Vitamin C 0.3 0.4 2.2 0.0 0.6 0.3 1.1 -1.5 0.4 0.2 0.7 -0.7 0.0 -0.2 0.2 -0.3 0.0 0.5
Knee pain experienced in last month 0.3 0.4 1.9 0.1 -0.1 -0.0 0.4 -0.1 0.7 0.4 0.8 -0.3 0.7 0.6 0.9 1.0 -0.2 1.4
Hypertension (Self-reported) 0.2 0.7 2.0 1.2 -0.3 1.4 0.9 -0.1 0.8 0.7 1.1 0.0 0.5 0.8 0.9 0.7 -0.9 0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 4.0 1.4 0.9 1.2 -2.0 1.4 0.2 -1.1 -0.3 -0.3 -0.9 -0.3 0.2 -0.2 0.4 -1.2
Illnesses of father: Heart disease 2.4 3.3 6.5 -0.4 -2.5 -0.7 2.2 2.0 0.3 2.4 2.2 2.5 2.5 1.8 0.6 1.7 -1.4 1.5
Illnesses of siblings: Diabetes 0.3 0.3 1.7 0.1 -0.7 -0.6 0.6 0.2 -0.7 0.4 -0.1 0.4 0.4 -0.0 -0.6 -0.0 -0.9 -1.3
Smoking status: Previous 0.2 0.4 1.7 -0.7 -0.5 -0.3 0.6 0.2 0.3 0.8 0.9 0.4 0.7 0.6 0.3 0.3 -0.2 1.3
Forced expiratory volume in 1-second (FEV1), predicted 2.1 4.4 7.0 -2.5 1.7 -2.6 -1.8 -1.4 -2.0 -2.1 -1.9 -1.9 -1.9 -2.4 -2.4 -2.6 2.4 -1.6
Whole body fat-free mass 0.2 0.9 2.6 -1.5 0.3 -1.6 -0.9 -0.6 -1.2 -0.1 0.2 -0.4 -0.4 -1.0 -1.3 -1.2 0.3 -1.0
Leg fat-free mass (right) 0.1 0.4 1.3 -0.9 0.0 -1.2 -0.5 -0.4 -0.9 0.1 0.7 -0.1 -0.2 -0.6 -0.9 -0.8 0.1 -0.9
Arm fat percentage (left) 0.2 0.8 2.0 0.2 -1.2 0.0 0.3 1.2 0.0 1.4 1.3 1.1 1.0 0.8 0.3 0.9 -1.0 0.2
Average weekly red wine intake 1.3 2.0 5.0 -1.6 -1.6 -2.2 -0.1 1.8 -2.1 0.9 0.5 1.4 0.8 -0.2 -1.8 -0.7 -0.6 -1.9
Handedness (chirality/laterality): Left-handed 0.5 0.5 1.9 0.0 -1.1 -0.4 0.1 0.9 -0.4 1.1 0.4 1.4 0.9 0.5 -0.3 0.2 -0.9 -0.7
Mood swings 0.3 0.6 3.0 0.1 1.1 0.6 -0.6 0.6 -0.1 -0.8 -0.9 -0.4 -1.0 -0.6 -0.1 -0.6 1.7 0.2
Loneliness, isolation 2.1 2.9 5.1 2.2 -1.2 2.3 1.0 1.4 2.0 1.3 0.9 1.4 1.5 1.9 2.0 2.1 -1.7 1.7
Long-standing illness, disability or infirmity 0.8 1.2 3.9 1.0 1.5 1.5 -0.9 -0.7 1.0 -1.2 -2.0 -1.7 -1.0 -0.5 0.6 -0.3 0.7 0.5
Ever had bowel cancer screening 0.2 0.3 0.9 -0.6 -0.3 -0.6 -0.4 0.7 -1.0 -0.1 -0.3 0.3 -0.3 -0.4 -0.8 -0.2 -0.0 -0.5
Diabetes diagnosed by doctor 0.3 0.4 1.3 -0.1 0.8 0.2 -1.1 -0.0 -0.4 -0.8 -0.6 -0.5 -1.0 -0.7 -0.3 -0.5 0.9 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 2.2 -0.1 1.1 0.6 -0.6 -0.8 0.8 -0.6 -0.0 -0.6 -0.3 -0.2 0.7 -0.2 0.9 1.5
Friendships satisfaction 2.4 2.9 5.5 -1.8 2.0 -0.9 -1.6 -2.3 -0.9 -2.2 -1.1 -2.2 -2.3 -1.8 -1.2 -1.9 1.6 -0.4
Qualifications: nursing, teaching 0.1 0.1 0.6 0.8 -0.1 0.1 -0.5 0.3 0.2 0.2 0.5 0.1 0.1 0.2 0.4 0.5 -0.1 0.2
Commuting to job workplace: Walk 2.3 2.5 4.2 -1.0 1.3 -1.3 -1.5 -1.4 -1.9 -1.7 -1.3 -1.5 -2.1 -1.9 -1.9 -1.8 1.0 -1.7
Eye problems/disorders: Cataract 0.4 0.5 3.3 -0.5 -0.4 -0.4 1.8 -1.0 -0.3 0.7 0.3 -0.1 0.7 0.1 -0.3 -0.1 -0.9 -0.0
Mouth/teeth dental problems: Mouth ulcers 0.2 0.4 1.2 0.8 0.1 0.6 -0.8 0.4 0.9 -0.2 0.2 -0.0 0.1 0.7 1.1 0.8 -0.5 0.8
Medication for cholesterol 0.3 0.4 2.7 -0.5 -0.1 -0.2 -1.0 1.7 0.3 -0.2 0.1 0.8 0.1 0.3 0.3 0.1 0.8 0.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.3 0.3 -0.0 0.5 -0.1 -0.2 0.3 0.2 0.3 -0.1 0.2 0.2 0.4 0.5 -0.3 0.4
Back pain experienced in last month 0.4 0.5 2.1 0.3 0.2 0.6 0.9 -0.3 1.2 0.5 0.3 -0.4 0.7 0.5 1.0 0.8 0.1 1.4
Mineral and other dietary supplements 0.6 0.8 3.2 0.7 0.7 0.3 -1.3 -0.7 -0.7 -0.9 -0.8 -0.5 -1.4 -0.8 -0.8 -0.9 0.2 -1.8
Breast cancer (self-reported) 0.9 1.1 3.2 1.8 -0.6 1.8 0.6 0.6 1.0 0.7 1.1 0.9 0.6 1.0 1.0 0.9 -1.1 0.4
Asthma (self-reported) 0.3 0.5 1.9 -0.3 -0.9 -0.9 1.4 0.2 -0.3 1.0 1.0 0.7 0.8 0.6 -0.2 0.3 -0.9 0.2
Osteoporosis (self-reported) 2.5 3.1 5.1 2.0 -1.5 1.7 1.7 0.7 1.8 1.8 1.9 1.2 1.7 2.0 2.0 2.1 -2.3 1.4
Osteoarthritis (self-reported) 0.3 0.4 2.6 -0.3 -0.2 0.2 -0.3 0.0 0.9 0.1 0.2 -0.1 0.5 0.7 0.9 0.9 -0.4 1.6
Medication: Aspirin 2.2 2.9 4.8 -1.1 1.5 -1.3 -1.8 -1.3 -2.1 -1.3 -1.2 -1.5 -1.9 -2.2 -2.1 -2.1 1.7 -2.0
Medication: Gliclazide 0.3 0.3 1.6 0.8 -0.4 0.8 -0.3 1.3 -0.1 0.3 -0.4 0.7 0.1 0.4 0.2 0.3 -0.4 -0.4
Illnesses of father: None of the above (group 1) 0.6 0.8 2.5 1.6 -0.7 1.5 0.9 0.3 0.8 0.7 0.5 0.6 0.6 0.6 0.6 0.5 -1.4 -0.5
Smoking status: Current 0.1 0.2 0.9 0.9 -0.1 0.5 0.5 -0.9 -0.1 0.2 -0.3 0.1 -0.1 -0.1 -0.2 -0.5 -0.3 -0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 4.1 -0.4 -0.9 -1.0 -0.3 0.6 -1.8 0.0 -0.5 0.4 -0.2 -0.4 -1.3 -0.3 -0.9 -2.0
Whole body water mass 0.2 1.0 2.7 -1.5 0.3 -1.6 -0.9 -0.6 -1.3 -0.2 0.1 -0.5 -0.5 -1.1 -1.4 -1.2 0.3 -1.2
Leg predicted mass (right) 0.1 0.5 1.4 -0.9 0.0 -1.2 -0.5 -0.4 -0.9 0.1 0.6 -0.1 -0.2 -0.6 -0.9 -0.9 0.1 -0.9
Arm fat mass (left) 0.1 0.4 1.3 -0.6 -0.7 -0.7 -0.2 0.7 -0.4 1.0 1.1 0.6 0.6 0.2 -0.3 0.2 -0.5 -0.0
Number of self-reported non-cancer illnesses 0.6 1.1 3.4 1.6 -0.5 1.9 0.3 0.3 1.1 0.7 0.9 0.6 0.7 1.1 1.3 1.2 -0.9 1.2
Average weekly champagne plus white wine intake 0.4 0.5 2.2 0.4 0.1 0.9 0.4 -0.1 1.3 0.1 -0.0 0.1 0.4 0.7 1.3 0.6 0.4 1.5
Miserableness 0.2 0.3 0.9 0.2 0.8 0.5 -0.4 -0.4 0.3 -0.4 -0.7 -0.9 -0.6 -0.2 0.4 -0.1 0.6 0.7
Guilty feelings 1.7 2.5 4.2 1.7 -1.8 1.3 1.5 0.9 1.2 1.7 1.4 1.4 1.9 1.9 1.3 1.9 -2.0 1.2
Wears glasses or contact lenses 1.5 1.8 4.9 -0.0 1.8 0.4 -1.4 -1.6 0.1 -1.7 -2.2 -2.2 -1.7 -1.2 -0.0 -0.9 0.6 -0.4
Ever taken oral contraceptive pill 1.4 1.6 3.9 -0.4 1.3 -0.7 -1.4 -0.9 -0.8 -2.0 -1.9 -1.4 -1.9 -1.3 -0.9 -1.1 1.0 -0.5
Hearing aid user 0.8 0.9 2.3 1.4 0.8 1.5 0.2 -1.1 1.2 -0.6 -1.5 -0.9 -0.4 0.3 1.1 0.6 -0.2 0.3
Mother’s age at death 0.2 0.2 1.0 -0.5 -0.4 -0.0 0.4 0.2 -0.2 0.9 1.0 0.6 0.6 0.2 -0.2 0.1 0.1 0.4
Financial situation satisfaction 1.0 1.2 3.3 -0.5 1.6 0.4 -0.5 -1.8 0.3 -1.3 -0.6 -1.8 -1.4 -0.9 0.1 -0.8 1.2 1.0
Tinnitus: Yes, now most or all of the time 3.8 4.4 6.9 2.0 -2.1 1.8 1.8 1.5 2.1 2.0 1.9 2.0 2.4 2.6 2.2 2.4 -2.3 1.8
Commuting to job workplace: Public transport 0.3 0.4 0.9 0.2 -0.3 0.9 0.1 0.3 0.8 0.7 0.7 0.6 0.6 0.7 0.8 0.7 -0.4 1.0
Eye problems/disorders: Glaucoma 0.8 1.0 1.9 0.5 -1.0 0.6 1.4 0.9 0.9 1.1 0.8 1.0 1.3 1.1 0.8 0.9 -0.6 1.4
Medication: Blood pressure 0.2 0.4 2.3 0.7 -0.2 0.8 1.5 -0.7 0.2 0.4 0.4 -0.4 0.3 0.3 0.2 0.2 -0.9 0.2
Pain type(s) experienced in last month: Hip pain 0.4 0.5 1.2 -0.2 -0.1 0.7 -0.9 1.0 1.0 0.0 0.0 0.2 0.7 0.6 0.9 0.9 0.1 1.1
Supplements: Fish oil (including cod liver oil) 0.4 0.5 3.3 -0.3 0.3 0.5 0.4 0.1 1.1 0.0 -0.1 -0.3 0.4 0.3 1.0 0.7 0.3 1.8
High cholesterol (Self-reported) 0.1 0.2 0.8 -0.3 0.6 0.0 -0.9 -0.2 0.1 -0.1 0.3 -0.3 -0.4 -0.2 0.1 -0.2 0.8 0.7
Medication: Bendroflumethiazide 0.3 0.5 3.0 0.4 -0.2 0.4 1.7 -1.5 0.2 0.8 0.0 -0.2 0.5 0.3 0.2 0.2 -0.9 0.4
Medication: Paracetamol 0.4 0.6 2.3 -1.0 1.0 -0.7 -0.5 -0.6 -0.3 -0.7 -0.6 -0.7 -0.4 -0.9 -0.5 -0.8 1.5 0.5
Medication: Lisinopril 0.5 0.6 1.9 0.8 -0.8 0.4 -0.1 1.4 0.2 1.0 1.4 1.2 0.5 0.8 0.3 0.6 -0.6 -0.3
Medication: Atorvastatin 2.3 2.9 6.1 -0.5 1.9 -0.5 -2.5 -1.6 -1.0 -2.2 -1.8 -1.9 -2.3 -1.8 -1.1 -1.8 1.6 -1.5
Illnesses of father: High blood pressure 0.4 0.5 2.2 0.1 0.7 -0.5 -1.4 -0.3 0.4 -0.7 -1.5 -0.9 -0.4 -0.1 0.4 -0.1 0.7 0.2
Alcohol drinker status: Never 0.4 0.5 1.8 -0.2 -0.2 -0.8 0.2 -0.3 -1.1 -0.0 -1.3 -0.3 -0.2 -0.6 -1.1 -0.6 -0.3 -1.3
Ever smoked 0.2 0.3 0.6 -0.5 -0.7 -0.5 0.7 -0.2 -0.8 0.7 -0.1 0.5 0.3 0.1 -0.5 -0.1 -0.7 -0.5
Basal metabolic rate 0.1 0.8 2.6 -1.5 0.3 -1.6 -0.9 -0.5 -1.2 -0.1 0.2 -0.5 -0.4 -1.0 -1.2 -1.1 0.3 -1.0
Leg fat percentage (left) 0.1 0.2 1.1 -0.7 0.4 -0.6 -1.0 0.0 -0.5 -0.2 -0.1 -0.6 -0.5 -0.5 -0.3 -0.3 0.4 0.0
Arm fat-free mass (left) 0.2 1.2 3.3 -1.7 0.6 -1.8 -1.1 -1.0 -1.3 -0.4 -0.2 -1.0 -0.6 -1.2 -1.4 -1.3 0.4 -0.8
Number of operations (self-reported) 2.1 3.2 5.4 -2.0 1.9 -1.7 -1.6 -2.3 -1.3 -2.1 -1.9 -2.1 -1.9 -2.0 -1.4 -1.8 1.5 -0.4
Average weekly beer plus cider intake 0.2 0.3 1.7 0.5 0.5 0.4 -1.3 0.5 0.1 -0.3 0.9 0.1 -0.5 -0.2 -0.0 -0.3 0.6 -0.7
Irritability 0.2 0.4 1.1 0.4 0.7 0.5 -0.8 0.4 0.3 -0.9 -1.1 -0.6 -0.8 -0.2 0.3 0.1 0.7 0.1
Risk taking 0.5 0.7 2.8 0.4 0.3 0.8 0.2 0.7 1.3 0.1 0.8 0.5 0.6 0.6 1.1 0.6 0.9 1.7
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.2 -0.3 -1.1 -0.8 -0.2 0.6 -1.1 0.7 0.5 0.9 0.3 0.1 -0.8 -0.1 -0.8 -0.6
Fractured/broken bones in last 5 years 0.2 0.3 0.7 0.7 0.8 0.5 -0.8 -0.1 0.3 -0.7 0.1 -0.7 -0.6 -0.4 0.2 -0.1 0.3 -0.7
Age started oral contraceptive pill 0.5 0.7 2.8 1.3 0.3 1.7 1.0 -0.8 0.6 -0.3 -1.1 -0.5 -0.3 0.3 0.7 0.7 -0.8 -0.1
Diastolic blood pressure, automated reading 1.0 3.0 6.2 1.7 -1.7 1.5 2.3 0.2 1.6 2.0 0.9 1.3 2.0 2.0 1.7 1.9 -2.5 1.2
Ever depressed for a whole week 0.4 0.5 1.3 -0.5 1.0 -0.0 -0.8 -0.1 0.1 -1.0 -1.1 -1.1 -1.0 -0.5 0.1 -0.5 0.7 0.4
Unable to work because of sickness or disability 1.0 1.3 2.8 -0.5 1.3 -0.5 -0.4 -1.7 -0.8 -1.3 -1.5 -1.5 -1.0 -1.4 -1.0 -1.6 0.9 -0.7
Commuting to job workplace: Cycle 1.1 1.3 4.0 1.8 -0.5 1.3 1.4 0.1 1.3 0.8 2.0 0.6 0.9 1.0 1.2 1.0 -1.4 -0.0
Myopia 0.5 0.7 1.9 -1.4 0.4 -1.4 0.0 -1.3 -1.0 -0.3 -0.6 -0.8 -0.6 -0.8 -0.9 -0.9 0.3 0.1
Vascular/heart problems diagnosed by doctor 0.3 0.9 2.2 -1.4 0.5 -1.5 -1.2 0.3 -0.9 -0.8 -1.1 -0.1 -0.5 -0.9 -1.0 -0.8 1.3 -0.6
Cholesterol lowering medication 0.2 0.3 1.2 0.0 0.3 -0.3 -0.2 -1.0 -0.9 -0.0 0.2 -0.3 -0.8 -0.7 -0.8 -0.5 0.1 -1.1
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 1.1 0.6 -0.7 0.6 0.2 1.0 0.4 0.6 -0.1 0.8 0.7 0.7 0.6 0.7 -0.7 0.4
Pain experienced in last month 0.9 1.5 3.2 -1.3 0.5 -1.1 -0.9 -0.6 -1.7 -1.0 -0.7 -0.6 -1.5 -1.4 -1.8 -1.8 0.6 -1.7
Supplements: Calcium 1.5 1.6 4.5 1.3 -1.4 0.9 2.1 0.8 0.7 1.6 1.0 1.1 1.6 1.3 0.8 1.0 -1.8 0.2
Basal cell carcinoma (self-reported) 0.1 0.1 0.5 0.2 -0.1 0.7 0.6 -0.1 0.4 0.1 0.4 0.2 -0.1 0.2 0.3 0.1 -0.2 0.5
Heart attack/myocardial infarction (self-reported) 0.8 1.0 2.0 -0.9 0.8 -0.8 -1.4 -0.8 -1.0 -1.1 -1.3 -1.0 -1.3 -1.2 -1.0 -0.7 0.8 -0.4
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 2.0 1.3 -0.7 0.7 1.2 0.2 0.4 0.8 0.0 0.1 0.7 0.4 0.5 0.8 -1.4 -0.9
Heart disease (siblings) 1.0 1.2 3.9 1.4 -0.0 1.6 0.1 0.4 2.0 0.3 -0.7 -0.5 0.6 1.0 1.7 1.1 -0.7 1.7
Alcohol drinker status: Previous 0.6 0.7 1.8 -0.5 1.0 -0.8 -1.4 -0.3 -0.1 -0.9 -1.2 -1.1 -0.8 -0.8 -0.2 -0.6 1.2 0.4
Pack years of smoking 2.6 3.8 9.8 -0.2 3.1 0.1 -1.7 -2.8 0.2 -2.6 -1.7 -3.1 -2.5 -1.9 -0.2 -1.5 2.2 -0.3
Impedance of whole body 0.1 0.3 1.8 0.5 -0.4 0.1 0.2 1.3 0.5 -0.2 -0.7 0.9 0.3 0.5 0.4 0.3 0.1 0.3
Leg fat mass (left) 0.2 0.6 1.8 -1.3 0.4 -1.3 -1.2 -0.2 -1.0 -0.2 0.2 -0.6 -0.5 -0.8 -0.9 -0.7 0.4 -0.4
Arm predicted mass (left) 0.2 0.9 2.9 -1.6 0.4 -1.7 -1.0 -0.8 -1.2 -0.2 -0.1 -0.8 -0.4 -1.0 -1.2 -1.1 0.2 -0.8