Hub : Genes

LRRC47

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0740	0.0280	3.9e-03	-0.002	0.009	0.003	NA	-0.001	6.9e-01	2.3e-02	1.4e-01	NA	4.6e-01
2	GTEx	Nerve Tibial	0.2062	0.0566	1.8e-04	0.092	NA	0.059	NA	0.061	4.5e-07	NA	5.0e-05	NA	3.9e-05
3	GTEx	Skin Sun Exposed Lower leg	0.0990	0.0370	2.8e-03	0.003	NA	0.016	NA	0.010	1.9e-01	NA	1.5e-02	NA	4.2e-02
4	GTEx	Thyroid	0.1270	0.0470	4.5e-03	0.011	NA	0.007	NA	0.006	4.5e-02	NA	8.8e-02	NA	1.1e-01
5	METSIM	Adipose	0.0798	0.0208	1.6e-06	0.055	0.051	0.079	0.068	0.078	1.2e-08	3.3e-08	7.1e-12	2.3e-10	8.9e-12
6	NTR	Blood	0.0559	0.0124	6.9e-11	0.044	0.037	0.063	0.051	0.038	5.2e-14	5.7e-12	1.7e-19	6.2e-16	2.2e-12
7	ROSMAP	Brain Pre-frontal Cortex	0.0812	0.0217	9.6e-06	0.044	0.057	0.052	0.058	0.042	2.3e-06	6.8e-08	2.4e-07	5.6e-08	3.2e-06
8	YFS	Blood	0.3260	0.0303	0.0e+00	0.305	0.287	0.334	0.344	0.323	7.5e-102	4.7e-95	7.9e-114	6.2e-118	3.0e-109
9	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0630	0.0380	9.6e-03	0.003	0.014	0.006	NA	0.010	1.9e-01	5.0e-02	1.4e-01	NA	8.6e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.1	0.2	0.8	-0.1	0.0	-0.3	-0.6	-0.2	0.1	0.0	0.9	-0.8
Bipolar Disorder or Schizophrenia	0.2	0.5	1.7	0.2	0.0	-1.3	-0.6	-0.9	-0.6	-0.1	-0.0	-1.1
Depressed Affect (Nagel 2018)	0.3	0.5	1.8	0.1	-0.3	-0.3	-1.0	-0.6	0.9	-0.7	1.3	-0.4
Depression (Nagel 2018)	0.2	0.3	0.7	-0.0	-0.8	-0.4	-0.3	0.0	-0.8	-0.2	-0.6	-0.8
Intelligence (Savage-Jansen 2018)	0.7	2.0	7.7	-2.8	1.1	0.7	1.8	1.3	-0.8	1.1	-1.3	-0.2
Neuroticism (Nagel 2018)	0.9	2.2	3.6	1.0	-1.2	-1.3	-1.7	-1.8	1.2	-1.5	1.6	-1.9
Schizophrenia (2018)	0.3	0.7	2.0	-0.1	-1.1	-1.4	-0.4	-0.9	-0.8	-0.4	-0.7	-0.8
Schizophrenia vs Biploar Disorder	0.3	0.3	0.8	0.7	0.0	-0.3	0.0	0.7	-0.5	0.8	0.4	0.9
Worry (Nagel 2018)	0.6	1.2	3.8	2.0	-1.1	-1.0	-1.2	-1.2	0.2	-0.6	0.0	-1.3
Alzheimer’s Disease (in mother)	1.3	1.5	3.2	-1.8	0.4	0.2	0.3	1.5	-1.7	1.2	-1.4	1.3
Alzheimer’s Disease (in father)	0.2	0.2	0.6	0.7	0.2	-0.2	-0.7	0.2	-0.5	-0.4	0.1	-0.2
Alzheimer’s Disease (including proxy)	0.4	0.6	1.3	-0.8	0.4	-0.5	-1.1	1.1	-1.1	0.2	0.4	0.8
Crohns Disease (2017)	0.6	1.3	4.0	-1.7	-0.0	-0.2	-0.2	0.8	-1.9	0.8	-2.0	-0.0
Irritable Bowel Disease (IBD)	0.2	0.5	1.4	-1.2	-0.5	0.5	-0.6	0.1	-1.1	0.1	-1.0	0.2
Ulcerative Colitis (UC)	0.2	0.5	1.1	0.1	-1.0	0.8	-0.7	-1.0	0.3	-0.7	0.6	0.2
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Reaction Time	0.5	0.9	5.0	2.2	-0.8	0.4	-0.9	-0.7	0.2	0.8	0.2	-0.2
Verbal and Numeric Reasoning (VNR)	0.8	1.9	8.1	-2.9	0.9	0.7	1.7	1.6	-0.2	0.9	-0.8	0.2
Breast Cancer	0.3	0.6	2.5	0.7	-1.3	-0.1	-1.6	-0.3	-0.8	0.1	-0.5	-0.0
Ovarian Cancer	3.7	4.8	8.2	-1.5	-2.7	-1.8	-2.4	-2.5	1.2	-2.9	1.3	-2.7
Prostate Cancer	1.4	2.0	6.5	-2.5	1.6	1.3	1.2	1.4	-0.1	0.7	-0.0	1.8
Age at First Birth	0.9	1.3	1.9	-1.1	-1.2	-1.0	-1.0	-1.2	0.9	-1.4	0.9	-1.4
Bipolar Disorder (2011)	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.5
Body Mass Index (BMI) (2010)	0.2	0.2	1.2	0.4	-0.2	0.2	-0.1	-0.1	1.1	0.4	-0.1	0.5
Coronary Artery Disease (CAD)	0.4	0.5	1.2	1.1	0.0	0.9	-0.3	0.0	-1.1	0.1	-0.7	0.8
Crohns Disease (2012)	1.1	1.8	6.9	-2.6	0.6	-0.6	0.9	0.9	-1.8	0.7	-1.7	0.0
Mean Putamen Volume	2.1	2.4	4.4	-1.2	1.7	2.1	1.4	1.5	-1.4	1.3	-1.2	1.7
Fasting Glucose	1.0	1.2	3.0	1.7	0.7	0.5	1.0	0.3	1.6	0.3	0.5	1.7
HbA1C	2.8	3.1	10.3	-0.2	-0.8	0.0	-1.4	-1.4	3.0	-1.8	3.2	-0.2
HDL Cholesterol	2.7	4.5	11.2	0.9	1.8	1.6	1.0	2.7	-2.5	3.3	-2.2	1.7
LDL Cholesterol	0.1	0.1	0.5	-0.2	-0.4	-0.7	-0.1	-0.2	0.2	-0.6	-0.0	-0.5
Lupus	0.7	1.0	2.4	-0.3	-0.8	-1.6	-0.4	-0.6	0.8	-1.4	0.4	-1.6
Neuroticism (2016)	0.6	0.9	2.2	-0.5	1.2	-0.2	-0.9	1.4	-1.5	1.0	-0.2	-0.4
Primary Biliary Cirrhosis	0.4	0.6	2.0	0.2	-0.7	-1.2	-0.6	-0.3	-1.4	0.2	-0.7	-0.1
Rheumatoid Arthritis	0.4	0.5	1.7	0.2	0.4	0.5	-0.8	1.3	-0.9	0.7	-0.4	0.4
Schizophrenia (2014)	0.4	0.9	2.9	0.1	-1.4	-1.7	-1.0	-0.6	-0.9	-0.4	-0.7	-0.5
Triglycerides	0.9	1.4	4.0	-0.2	-1.0	0.5	-0.6	-1.4	1.8	-1.3	2.0	-0.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	3.2	0.7	0.0	0.6	-0.4	-0.5	1.8	-0.3	1.4	-0.4
Ulcerative Colitis	0.2	0.3	1.0	-1.0	-0.3	1.0	-0.8	0.0	-0.5	-0.1	0.1	-0.0
Blood Eosinophil Count	0.1	0.9	6.6	-1.1	0.5	0.2	2.6	-0.3	0.4	-0.1	0.0	0.2
Blood Platelet Count	0.2	2.4	7.7	-1.4	-1.1	-1.6	2.8	-2.1	-0.4	-0.1	-1.6	-0.9
Blood Red Count	3.5	33.7	104.0	-3.7	6.2	3.6	10.2	3.8	-2.8	5.7	-7.0	5.6
Blood White Count	0.5	3.7	8.2	-2.8	2.2	-0.0	2.9	1.3	-1.4	1.3	-2.5	0.9
Heel T-Score	0.1	0.9	6.1	2.5	0.5	0.9	0.7	0.1	-0.0	0.5	0.4	0.6
BMI	0.4	2.3	5.3	-1.7	1.9	2.3	1.1	0.4	1.1	0.1	1.3	2.0
Height	0.3	5.5	15.8	4.0	2.4	2.3	0.6	2.5	0.1	2.9	-0.2	2.8
Waist Hip Ratio (WHR)	0.4	2.0	3.5	0.3	-0.7	-1.7	-1.8	-1.7	0.4	-1.6	1.9	-1.6
Systolic Blood Pressure	0.6	3.1	17.5	4.2	-1.4	-0.0	-1.6	-0.4	1.2	-0.2	1.7	-1.1
Smoking Status	0.4	0.8	2.9	-0.1	1.2	0.5	0.2	0.3	1.3	0.3	1.7	1.0
Allergy or Eczema	0.3	0.8	1.7	1.3	-1.1	0.1	-0.4	-0.1	-0.6	1.3	-1.1	-0.8
Cardiovascular Disease	0.3	1.0	3.0	1.4	-0.3	-0.9	-0.4	-0.8	1.3	-0.8	1.7	-0.5
Hypothyroidism (self reported)	0.2	0.4	0.8	0.3	0.6	0.7	0.8	0.0	0.9	-0.5	0.9	0.1
Respiratory disease	0.5	1.1	4.7	2.2	-1.1	-0.8	-1.0	-0.4	-0.1	0.6	0.4	-1.4
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.9	-1.1	1.1	1.0	1.4	-0.1	0.4	-0.2	0.0	0.8
Lung FEV1/FVC ratio	0.7	3.4	11.3	0.9	0.6	-0.7	-0.7	-1.3	3.4	-2.8	2.7	0.4
Lung FVC	0.2	0.8	2.9	0.9	-0.4	-1.7	-0.5	0.4	-0.7	0.5	0.5	-1.3
Neuroticism	0.4	1.0	2.2	1.3	-0.0	-1.1	-1.5	-0.8	0.3	-0.5	1.2	-1.3
Chronotype (morning person)	1.0	2.4	7.3	1.5	-0.5	-0.5	1.3	-1.4	2.7	-2.3	1.4	-0.7
Hair Pigment	0.0	0.5	2.5	-0.9	-0.4	-0.6	1.6	-0.5	0.4	-0.2	-0.5	-0.5
Tanning	0.5	6.0	10.3	1.0	2.8	2.5	0.1	3.0	-3.2	3.1	-2.2	2.3
Hand grip strength (left)	0.5	1.4	3.4	0.6	0.9	1.6	-0.1	1.7	-0.4	1.8	0.2	1.6
Number of treatments/medications taken	0.4	0.7	2.3	1.4	0.7	0.1	0.5	0.7	-0.5	1.5	-0.7	0.3
Average weekly spirits intake	0.3	0.4	2.2	-0.6	0.1	-0.2	1.0	-0.3	-0.3	0.4	-1.5	-0.1
Sensitivity / hurt feelings	0.9	1.5	4.8	0.3	-0.7	-1.3	-2.2	-0.8	-0.2	-0.7	1.5	-1.8
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.8	-0.2	-0.2	-0.8	-1.7	0.4	-1.5	0.0	0.0	-0.8
Hearing difficulty/problems: Yes	0.4	0.6	1.5	0.5	0.2	0.7	1.2	0.1	-0.1	0.9	-1.2	1.1
Relative age of first facial hair	1.2	2.6	5.5	-1.2	1.7	1.4	2.3	1.2	-0.9	1.7	-1.7	1.9
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.3	0.7	0.2	1.1	-0.6	0.3	-0.7	0.6	-0.3	-0.2
Ever used hormone-replacement therapy (HRT)	0.9	1.1	7.2	2.7	0.9	0.3	-0.1	0.4	0.8	0.7	0.5	0.4
Ever had hysterectomy (womb removed)	0.4	0.5	1.6	0.1	-0.0	0.3	0.9	-0.7	1.2	-0.9	0.8	0.2
Systolic blood pressure, automated reading	0.7	1.9	10.0	3.2	-0.6	1.0	0.3	-0.5	2.0	-0.6	1.1	0.1
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	3.6	-1.9	0.5	0.1	0.4	-1.0	1.2	-1.1	1.4	-0.5
Angina	0.8	1.0	2.2	1.2	-1.0	-0.6	-0.3	-1.5	1.3	-0.8	0.7	-1.0
Medication for hormone replacement therapy	0.6	0.6	2.8	0.3	0.7	-0.2	-0.9	1.7	-0.6	0.9	-0.2	0.6
Vitamin and mineral supplements	0.5	0.7	2.0	0.6	1.2	0.6	-0.3	1.4	-0.3	0.6	0.2	1.1
Supplements: Zinc	0.1	0.1	0.4	0.2	0.2	0.3	0.5	0.1	0.1	-0.2	0.1	0.6
Medication: Co-codamol	1.0	1.2	2.5	0.2	0.9	0.5	1.1	1.3	-1.2	1.6	-1.3	1.0
Medication: Metformin	0.5	0.7	3.2	-1.8	0.4	0.3	0.9	-0.5	0.5	-0.9	0.2	-0.7
Diabetes (father)	0.6	0.7	1.9	-1.4	1.3	0.8	0.9	0.4	0.1	-0.0	0.7	0.8
Diabetes (mother)	0.8	1.0	4.0	1.3	1.0	0.3	-0.7	-0.0	1.0	-0.5	2.0	-0.6
Severe depression (siblings)	0.3	0.4	0.6	0.7	0.7	0.8	0.0	0.6	0.1	0.7	0.7	0.6
Pack years adult smoking proportion	0.4	0.6	1.7	-0.9	0.3	-0.6	-0.1	-0.3	0.7	-1.2	1.3	-1.0
Impedance of leg (right)	0.7	3.3	11.8	3.4	-2.2	-2.1	-1.9	-0.9	-0.2	-0.7	0.6	-1.9
Leg fat-free mass (left)	1.0	5.4	12.0	-1.9	3.1	3.5	2.4	1.8	1.2	1.5	0.4	3.2
Trunk fat percentage	0.3	1.2	3.1	1.0	0.4	1.7	1.1	-0.6	1.8	-0.6	0.6	1.1
Hand grip strength (right)	1.0	2.7	5.2	1.2	2.0	2.3	0.4	2.2	-0.3	2.3	0.2	1.9
Townsend deprivation index at recruitment	0.7	1.1	3.5	-0.9	0.1	-1.9	-1.4	-0.4	-0.2	-0.8	1.2	-1.1
Current tobacco smoking	0.5	0.9	2.1	0.5	0.8	1.0	0.4	1.1	-0.8	1.5	-0.0	1.4
Average weekly fortified wine intake	0.2	0.2	1.0	0.4	-1.0	0.1	-0.4	-0.7	-0.0	0.3	0.4	0.3
Maternal smoking around birth	0.3	0.4	1.0	1.0	-0.1	-0.6	-0.8	0.0	0.1	-0.9	0.7	-0.4
Fed-up feelings	0.2	0.4	1.8	-0.4	0.8	-0.3	-0.6	0.2	0.6	-0.4	1.4	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	3.5	-1.4	-0.8	-0.6	-1.0	0.4	-1.9	0.2	-1.1	-1.2
Relative age voice broke	0.1	0.2	0.5	-0.2	-0.2	-0.5	-0.5	-0.7	-0.5	-0.4	0.4	-0.1
Taking other prescription medications	0.3	0.5	1.0	1.0	0.9	0.7	0.7	0.6	-0.2	0.9	0.2	0.8
Age when periods started (menarche)	0.7	1.8	6.6	-1.5	-0.8	-0.9	0.2	-1.5	1.1	-1.3	0.8	-2.6
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	2.0	0.2	-0.0	-0.2	1.4	-0.4	1.0	-0.5	0.9	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.7	0.8	0.1	-0.0	0.3	-0.4	0.4	-0.3	0.8	0.8
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	2.2	0.4	1.5	0.4	0.9	0.5	-0.8	0.6	0.8	0.5
Qualifications: CSEs or equivalent	0.4	0.5	1.6	0.5	0.5	0.1	-1.3	0.9	0.1	0.9	0.4	0.6
Serious illness, injury or assault to yourself	0.7	0.9	3.6	-0.4	-0.9	-0.7	-1.9	0.0	-1.2	-0.5	0.6	-0.9
High blood pressure	0.6	1.8	3.5	0.9	-1.4	-1.0	-0.4	-1.6	1.9	-1.5	1.2	-1.5
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.7	1.3	-0.7	0.4	-0.5	-0.1	-0.2	0.9	-0.6	-1.0
Multivitamins +/- minerals	1.0	1.3	3.3	-0.1	-1.5	-1.2	-0.4	-1.6	0.2	-1.2	0.5	-1.8
Stomach or abdominal pain in last month	0.3	0.4	1.6	0.1	-0.8	-0.6	-1.3	0.1	-0.5	0.3	-0.5	-0.4
Supplements: Glucosamine	0.4	0.5	1.1	0.9	-0.4	1.1	-0.2	0.1	-1.0	0.4	-1.0	0.3
Diverticular disease/diverticulitis (self-reported)	2.7	3.2	9.2	-1.9	1.4	3.0	3.0	0.6	1.2	0.3	-1.0	1.6
Medication: Atenolol	3.2	4.0	8.8	0.6	-1.2	-0.8	-0.7	-2.7	2.6	-2.8	3.0	-1.6
Medication: Levothyroxine sodium	0.3	0.5	1.8	0.6	0.4	0.9	0.0	-0.6	1.0	-0.5	1.3	-0.1
Sitting height	0.8	5.4	10.8	1.5	3.2	2.9	0.3	3.2	-1.2	3.3	0.1	2.4
Chronic bronchitis/emphysema (father)	0.6	0.7	3.6	1.9	0.5	0.1	-0.3	1.2	0.2	0.3	0.4	0.5
High blood pressure (mother)	1.6	2.2	5.2	1.0	-2.2	-0.6	-2.3	-1.5	0.5	-0.7	1.8	-1.4
Body mass index (BMI)	0.6	2.6	7.3	-1.6	1.7	2.7	1.8	0.1	1.7	-0.3	0.8	1.9
Impedance of leg (left)	0.9	4.1	14.6	3.8	-2.4	-2.1	-2.4	-1.2	-0.2	-0.7	0.8	-2.1
Leg predicted mass (left)	1.0	5.5	12.4	-1.9	3.2	3.5	2.3	1.9	1.1	1.5	0.4	3.3
Trunk fat mass	0.5	1.9	6.2	0.3	1.4	2.5	1.4	0.2	1.7	-0.1	0.8	1.9
Waist circumference	0.6	2.4	5.8	-1.2	1.9	2.4	1.3	0.1	2.0	-0.4	1.5	1.6
Number of incorrect matches in round	0.8	1.3	3.7	1.4	0.0	0.5	0.4	0.2	-1.9	1.9	-1.2	0.6
Past tobacco smoking	0.3	0.6	2.6	-1.6	-0.1	-0.2	0.0	0.2	-1.3	-0.1	-0.7	-0.4
Alcohol usually taken with meals	0.5	0.9	2.5	1.6	0.6	1.0	0.9	0.9	-0.2	1.3	-0.5	0.6
Nervous feelings	0.8	1.6	3.6	1.7	-1.3	-1.9	-1.4	-1.2	-0.6	-0.9	0.0	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.4	0.4	0.5	0.5	-1.6	1.1	-1.3	0.9	-0.5	-0.2
Hearing difficulty/problems with background noise	0.8	1.3	4.3	0.4	1.0	2.1	0.5	0.6	0.2	1.3	-0.5	1.9
Hair/balding pattern: Pattern 2	0.8	1.0	2.4	0.7	-1.1	-0.4	-0.7	-0.9	0.8	-1.2	0.9	-1.6
Had menopause	0.6	0.8	2.7	1.6	0.6	0.2	1.2	0.3	1.0	0.6	0.4	0.9
Had other major operations	2.5	3.0	7.8	0.2	2.4	2.6	2.8	1.0	1.4	0.8	-0.6	1.7
Forced vital capacity (FVC)	0.3	1.3	4.5	0.6	1.2	-0.1	-0.2	1.9	-1.1	2.1	0.2	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	3.0	1.7	0.5	0.3	0.6	0.1	-0.1	1.0	0.1	1.2
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	2.8	-1.3	-0.6	-0.9	0.4	-1.4	0.1	-1.7	-0.5	-0.3
Qualifications: None of the above	0.7	1.6	3.7	0.5	1.4	0.9	0.7	-0.3	1.8	-1.9	1.9	0.3
Financial difficulties in last 2 years	1.5	2.1	8.0	-0.3	-1.9	-1.4	-2.8	-1.3	-0.1	-0.6	1.4	-0.9
Mouth/teeth dental problems	0.3	0.5	1.7	0.3	0.0	0.7	1.3	-0.4	-0.1	0.6	-0.8	0.9
Heart attack	0.3	0.4	1.1	-0.5	-0.2	-1.0	0.3	-0.6	0.7	-0.8	0.4	0.1
Allergy	0.6	1.4	5.1	-1.4	1.5	0.9	1.5	0.6	-0.0	-0.3	0.1	2.3
Pain all over the body in last month	1.0	1.0	3.7	-0.9	0.1	-0.3	-1.1	0.8	-1.9	0.5	-1.4	-0.8
Diabetes (self-reported)	0.8	1.2	3.3	-1.7	1.8	0.9	1.2	0.8	0.3	0.0	0.1	1.3
Hayfever/allergic rhinitis (self-reported)	0.3	0.5	2.8	-0.3	0.0	0.5	1.7	-0.2	0.4	0.3	-0.7	0.4
Medication: Ramipril	0.2	0.3	1.7	-0.3	0.1	0.7	-0.5	0.4	-0.3	0.2	0.1	1.3
Medication: Simvastatin	0.8	1.1	2.3	0.5	-1.2	-1.5	0.0	-1.5	0.8	-1.4	0.4	-1.1
Fluid intelligence score	0.7	1.4	2.7	-1.6	0.8	0.2	1.6	1.6	-0.3	1.5	-1.0	0.9
Illnesses of siblings	0.3	0.4	2.2	-0.1	0.3	0.3	-1.5	0.3	-0.9	0.7	0.2	0.3
Neuroticism score	0.5	1.0	5.0	0.9	0.2	-1.0	-2.2	-0.1	-0.1	-0.4	1.2	-1.0
Weight	0.9	4.5	13.5	-0.8	2.9	3.7	1.9	1.4	1.4	1.0	1.1	2.9
Impedance of arm (right)	0.9	4.2	10.6	2.4	-3.2	-2.7	-1.3	-2.1	0.2	-1.3	-0.6	-2.4
Arm fat percentage (right)	0.4	1.7	4.5	-0.9	-0.0	1.7	1.5	-1.4	2.1	-1.3	0.5	0.8
Trunk fat-free mass	1.1	6.3	14.5	-1.8	3.8	3.8	1.6	2.4	0.8	1.7	1.5	3.3
Hip circumference	1.1	4.7	12.2	-1.1	2.8	3.5	2.6	1.2	1.9	0.7	0.6	2.8
Time employed in main current job	0.2	0.2	0.5	-0.3	-0.7	-0.1	0.4	-0.7	0.2	-0.0	-0.3	0.5
Alcohol intake versus 10 years previously	0.7	1.0	4.6	0.6	-0.3	0.2	1.5	-1.1	2.1	-0.5	0.3	0.2
Father’s age at death	1.0	1.3	2.9	-0.2	-0.2	-1.2	0.2	-1.5	1.7	-1.6	0.8	-1.3
Worrier / anxious feelings	0.5	0.9	3.6	0.7	-0.0	-0.9	-1.9	-0.4	0.2	-0.6	1.0	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.6	0.9	1.3	1.1	-0.5	0.6	-0.7	0.9	-0.8	0.2
Falls in the last year	0.5	0.7	1.8	-0.9	-1.0	-0.7	-1.0	-0.6	-0.5	-1.0	-0.3	-1.3
Hair/balding pattern: Pattern 3	0.2	0.3	1.1	-1.0	-0.3	-0.1	0.9	-0.2	-0.2	-0.4	-0.9	-0.1
Number of live births	0.5	0.7	3.8	0.0	0.2	2.0	0.8	0.3	-0.1	0.7	-0.9	0.9
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.1	0.7	1.1	-0.2	-0.3	1.0	-0.0	0.9	0.9	0.1
Pulse rate	0.2	0.3	1.2	0.4	0.1	0.2	0.1	-0.4	1.1	-1.0	0.5	0.1
Happiness	0.3	0.3	0.7	0.5	-0.6	-0.3	0.3	-0.0	-0.8	0.4	-0.8	-0.6
Noisy workplace	0.4	0.5	1.6	0.7	1.3	1.1	0.4	0.6	-0.6	0.4	-0.5	0.5
Qualifications: A levels/AS levels or equivalent	0.4	0.9	2.7	-0.5	-0.0	-0.2	-1.2	1.6	-1.6	0.7	-0.1	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.7	0.2	0.1	0.4	0.9	-0.2	-0.0	0.2	-0.0	0.1
Mouth/teeth dental problems: Dentures	0.1	0.1	0.2	0.2	-0.5	-0.2	-0.4	-0.4	0.2	-0.2	-0.1	-0.5
Asthma	1.0	2.0	5.3	1.3	-1.5	-1.8	-1.4	-1.0	0.9	-0.9	0.8	-2.3
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	4.8	0.2	2.2	1.2	-0.6	1.6	-0.7	1.9	-0.2	1.6
Medication: Cholesterol lowering	2.4	3.7	7.0	-0.7	-2.5	-2.6	-1.6	-2.0	-0.5	-2.2	0.5	-2.6
Depression (self-reported)	1.0	1.2	4.8	1.8	-0.0	0.9	0.7	-0.1	-0.4	0.6	-2.2	0.8
Medication: Lansoprazole	0.1	0.1	0.5	-0.2	-0.3	-0.5	-0.2	-0.7	-0.2	0.5	0.2	0.4
Prospective memory result	0.8	1.0	3.0	-0.0	-0.6	-0.3	-0.7	-1.5	0.7	-1.7	0.7	-1.2
Lung cancer (father)	0.4	0.4	1.9	-1.4	-0.0	-0.4	1.2	-0.0	-0.2	0.1	-0.7	-0.1
Illnesses of mother	0.5	0.6	1.8	0.4	0.7	-0.2	1.2	-0.5	1.3	-0.4	-0.1	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	4.2	0.6	-0.2	-1.2	-1.8	0.2	0.4	-0.5	2.1	-1.4
Pulse wave Arterial Stiffness index	0.3	0.4	1.3	0.9	0.3	1.1	0.4	0.2	0.6	0.6	-0.3	0.1
Impedance of arm (left)	0.9	4.0	9.3	2.3	-3.0	-3.0	-1.6	-1.4	-0.7	-0.9	-1.1	-2.5
Arm fat mass (right)	0.6	2.3	7.4	-1.2	1.4	2.7	1.8	-0.2	1.9	-0.5	0.8	1.8
Trunk predicted mass	1.1	6.4	14.6	-1.9	3.8	3.8	1.6	2.4	0.7	1.7	1.5	3.3
Standing height	0.5	5.2	10.4	1.6	3.0	2.7	0.5	3.2	-0.6	3.0	0.5	2.8
Length of working week for main job	0.5	0.6	1.9	-0.9	1.0	0.7	0.1	1.4	-0.8	-0.1	-0.6	0.4
Exposure to tobacco smoke at home	0.1	0.1	0.6	-0.4	0.0	-0.3	0.2	-0.3	-0.1	-0.5	0.1	-0.8
Breastfed as a baby	0.8	1.0	4.7	0.5	-0.1	1.0	2.2	-0.1	0.2	0.4	-1.7	0.3
Tense / ‘highly strung’	1.2	2.0	4.1	0.6	-1.8	-1.7	-1.8	-1.2	0.1	-1.4	0.7	-2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.1	0.9	0.4	-0.2	-1.1	0.3	-0.6	0.6	0.0	0.1
Hair/balding pattern: Pattern 4	0.6	1.4	3.8	-0.3	1.6	1.0	0.3	2.0	-1.0	1.5	-0.1	1.4
Birth weight of first child	0.9	1.6	6.5	-0.5	1.6	1.4	2.5	0.1	1.6	0.1	0.2	0.8
Peak expiratory flow (PEF)	0.3	0.8	1.8	1.3	1.3	0.5	0.7	0.5	1.0	1.0	0.6	0.5
Pulse wave reflection index	0.3	0.4	0.8	0.6	0.6	0.8	0.6	0.4	-0.1	0.9	-0.5	0.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.2	-0.3	-0.3	-0.9	0.4	-0.9	0.8	-1.5	0.1	-0.6
Loud music exposure frequency	0.7	0.8	2.6	1.6	-0.1	0.5	0.5	-0.6	-0.3	1.1	-1.4	-0.6
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	2.6	-0.6	0.4	1.4	-0.6	1.6	-1.0	1.6	-0.5	1.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.9	-0.1	0.8	-0.5	1.0	0.7	0.8	0.4	0.0	0.2
Blood clot in the leg (DVT)	0.5	0.6	1.3	0.4	-0.8	-0.8	-0.4	-1.1	1.2	-0.7	-0.0	-1.0
Medication: Paracetamol	0.3	0.4	1.9	1.4	0.1	0.5	0.1	0.1	0.3	1.1	-0.5	-0.3
Headache pain in last month	3.0	5.2	12.4	-0.9	2.3	2.5	0.0	3.0	-2.0	3.5	-1.5	2.6
Medication for cholesterol, blood pressure or diabetes	1.7	2.9	6.2	0.4	2.1	1.9	1.7	1.6	-0.5	2.5	-1.4	2.0
Glaucoma (self-reported)	0.4	0.5	1.8	0.3	-0.2	-0.7	0.2	-0.3	0.1	-0.1	-1.2	-1.4
Gout (self-reported)	0.4	0.5	1.8	-1.3	0.1	-0.1	-0.7	1.3	-0.7	0.3	-0.1	0.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.3	0.6	1.0	1.1	-0.2	0.4	0.5	-0.3	1.5	0.4
Medication: Amlodipine	0.3	0.4	1.3	-0.2	0.6	-1.1	0.1	0.3	0.7	-0.8	0.8	-0.0
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.2	1.1	-0.7	0.1	-0.8	-0.2	0.4	0.3	0.1	-0.4
Birth weight	0.3	0.6	3.1	0.1	0.5	-0.2	1.8	0.2	0.1	-0.1	-1.2	-0.4
Chronic bronchitis/emphysema (mother)	2.1	2.5	6.7	0.2	1.8	1.0	0.4	2.6	-2.2	1.8	-1.0	1.5
High blood pressure (siblings)	0.8	1.1	5.6	0.3	1.0	0.4	2.4	0.6	1.0	0.6	-1.2	0.5
Forced vital capacity (FVC), Best measure	0.3	0.9	2.1	0.5	-0.1	-1.0	-1.5	1.1	-0.7	0.7	1.1	-1.3
Body fat percentage	0.3	1.3	3.9	0.6	0.4	1.8	1.0	-0.8	2.0	-0.9	0.8	0.9
Leg fat percentage (right)	0.6	2.1	6.3	0.1	1.0	2.5	1.7	-0.5	2.2	-0.8	1.0	1.4
Arm fat-free mass (right)	1.2	6.3	15.6	-1.2	4.0	3.7	1.6	2.7	0.4	2.0	1.0	3.2
Exposure to tobacco smoke outside home	0.6	0.8	2.7	0.6	0.0	-0.2	-1.0	-0.5	0.8	-1.5	1.6	-0.6
Comparative body size at age 10	0.1	0.2	0.6	-0.7	-0.8	0.0	-0.2	-0.3	0.3	0.1	-0.4	-0.8
Number of full brothers	0.4	0.5	1.7	-0.2	-0.3	-0.5	0.2	-1.3	0.6	-0.9	-1.0	-0.8
Worry too long after embarrassment	0.4	0.7	2.8	-0.3	-0.1	0.3	-1.7	-0.1	0.6	-1.1	1.2	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.6	0.7	0.1	0.7	-0.7	-0.3	-0.8	-0.2	-0.5	-0.6
Wheeze or whistling in the chest in last year	0.3	0.5	1.1	0.8	-1.1	-0.0	-1.0	-1.0	-0.5	0.2	-0.3	-0.1
Number of children fathered	1.6	1.8	4.5	1.3	1.8	1.4	2.1	0.4	0.6	0.7	-0.9	1.6
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.2	1.5	-0.2	0.3	-0.2	0.5	-1.5	0.9	-1.1	-0.4
Age at first live birth	0.9	1.5	5.8	-0.5	0.3	-0.2	-0.7	1.6	-2.4	1.3	-1.6	0.5
Pulse wave peak to peak time	0.3	0.3	1.2	-0.8	-0.3	-1.1	-0.5	-0.2	-0.5	-0.5	0.5	-0.1
Health satisfaction	0.6	0.8	1.7	-0.6	-0.3	-0.1	-0.8	-0.9	1.0	-1.3	1.1	-1.0
Shortness of breath walking on level ground	1.6	1.9	5.8	-0.7	-0.1	0.1	-1.0	-1.3	2.0	-2.4	1.8	-1.0
Qualifications: College or University degree	0.3	0.8	2.4	-0.6	-0.3	-0.2	0.8	0.3	-1.2	0.6	-1.6	-1.4
Eye problems/disorders: None of the above	0.6	0.7	2.1	0.9	-1.2	0.5	-1.4	-0.2	-0.6	0.7	0.6	0.1
Mouth/teeth dental problems: Loose teeth	0.5	0.5	1.7	0.8	-1.0	-1.3	-0.6	-0.4	0.2	-0.7	0.7	-0.1
Emphysema/chronic bronchitis	0.2	0.3	1.0	0.5	-0.2	1.0	0.4	-0.6	0.7	0.1	0.0	0.3
Medication for pain relief, constipation, heartburn	0.5	0.8	2.5	-0.2	-1.0	-0.2	-0.0	-0.7	0.8	-1.6	1.5	0.1
Neck or shoulder pain in last month	0.6	0.8	2.3	-0.7	0.7	1.1	1.5	0.2	0.6	0.2	-0.0	1.5
Medication: Blood pressure	0.6	1.0	2.0	0.3	-0.9	-0.9	-1.3	-0.7	0.9	-1.4	1.3	-1.0
Angina (self-reported)	0.7	0.9	2.6	1.2	-0.9	-0.3	0.0	-1.6	1.3	-0.7	0.6	-0.7
Migraine (self-reported)	0.4	0.5	2.0	0.3	0.3	-0.7	-0.4	0.4	1.4	0.3	1.3	0.2
Medication: Ibuprofen	1.5	1.8	5.5	-0.2	2.3	1.1	-0.5	1.8	-0.8	1.8	0.0	1.5
Medication: Allopurinol	0.9	1.3	2.8	-0.6	-0.7	-1.0	-1.5	-0.1	0.6	-1.7	1.5	-1.4
Medication: Omeprazole	0.4	0.5	2.1	1.4	0.1	0.1	0.5	-1.0	0.7	0.2	-0.5	-0.4
Medication: Seretide 50 evohaler	0.4	0.5	1.0	0.4	-0.8	-0.7	-1.0	-0.8	-0.6	-0.6	-0.0	-0.9
Mean time to correctly identify matches	0.8	1.4	8.5	2.9	-1.0	0.8	-0.1	-1.2	1.1	0.4	0.1	0.2
Heart disease (mother)	0.4	0.4	1.5	-0.8	0.6	1.2	-0.0	0.8	-0.8	0.3	-0.3	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.0	0.1	0.3	1.4	-0.4	1.1	-0.9	1.4	-0.4	0.6
Whole body fat mass	0.5	2.1	6.7	-0.0	1.4	2.6	1.4	-0.1	2.0	-0.2	1.1	1.7
Leg fat mass (right)	0.8	3.1	9.5	-0.2	1.7	3.1	1.9	0.1	2.4	-0.3	1.2	2.1
Arm predicted mass (right)	1.2	6.1	14.2	-1.2	3.7	3.8	1.4	2.7	0.5	1.9	1.3	3.3
Pulse rate, automated reading	0.1	0.4	0.8	-0.9	0.3	-0.2	-0.4	0.8	-0.8	0.3	-0.9	-0.4
Alcohol intake frequency.	0.4	1.0	3.2	-0.1	1.8	0.7	0.8	0.6	-0.5	1.2	-0.5	1.6
Comparative height size at age 10	0.4	2.5	6.2	1.3	1.4	1.3	-0.2	2.5	-1.0	2.4	-0.2	1.9
Number of full sisters	0.9	1.1	3.7	-0.4	-0.3	0.5	-0.3	-0.7	1.9	-1.3	1.9	-0.3
Suffer from ‘nerves’	0.6	0.9	2.3	0.9	-1.0	-0.9	-1.5	-1.3	-0.0	-0.7	0.3	-0.8
Overall health rating	0.6	1.3	3.0	-1.6	0.7	1.7	0.2	-0.4	1.7	-1.1	1.1	0.0
Chest pain or discomfort	0.4	0.5	2.1	1.4	-0.6	0.4	-0.4	-0.5	-0.5	0.3	-1.1	-0.4
Had major operations	0.2	0.2	0.5	-0.2	0.7	0.0	0.4	0.7	-0.2	0.5	0.6	0.1
Age at last live birth	1.0	1.5	5.3	-0.5	0.6	0.4	-0.1	1.6	-2.3	1.5	-1.5	0.4
Family relationship satisfaction	0.2	0.3	0.8	-0.2	0.3	-0.6	0.9	-0.1	-0.1	0.6	-0.5	-0.7
Leg pain on walking	1.1	1.4	5.1	0.2	1.3	1.4	0.0	-0.5	1.7	-0.9	2.2	0.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.3	1.5	-0.3	-0.6	-0.4	-0.2	-0.2	1.0	-0.3	1.1
Commuting to job workplace: Car/motor vehicle	2.1	2.4	4.8	-1.4	1.6	1.6	1.9	1.7	-0.9	1.2	-1.0	2.2
Illness, injury, bereavement, stress in last 2 years	2.1	2.6	7.3	0.7	2.0	0.8	2.7	1.3	-0.5	1.6	-2.3	0.9
Medication: Aspirin	1.2	1.6	5.3	-0.3	-1.2	-2.3	0.6	-1.3	0.3	-0.8	-0.8	-2.0
Supplements: Vitamin C	0.4	0.5	1.8	0.6	-0.5	0.9	-0.5	0.1	-0.6	0.8	-0.1	1.4
Knee pain experienced in last month	1.2	1.9	7.7	-1.2	1.7	2.8	1.7	0.5	0.8	0.3	0.2	1.2
Hypertension (Self-reported)	0.6	1.6	2.8	0.6	-1.4	-1.3	-0.4	-1.5	1.7	-1.4	0.9	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.8	0.5	-0.2	0.3	0.5	-0.2	-0.2	0.8	-0.9	0.4
Illnesses of father: Heart disease	1.9	2.6	7.0	1.3	-2.6	-1.4	-1.2	-1.7	0.5	-1.9	0.1	-2.0
Illnesses of siblings: Diabetes	0.6	0.8	3.0	-0.1	-0.5	0.5	1.7	-0.2	0.5	0.5	-1.6	0.6
Smoking status: Previous	0.4	0.6	2.6	0.7	-0.4	-0.1	-0.4	-0.9	1.6	-0.6	0.7	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	1.0	0.1	-0.2	0.7	-1.0	0.7	0.3	0.3	1.0	0.1
Whole body fat-free mass	1.1	6.1	14.5	-1.8	3.6	3.8	1.9	2.1	1.1	1.6	1.2	3.3
Leg fat-free mass (right)	1.0	5.3	12.4	-1.8	3.1	3.5	2.2	1.8	1.1	1.6	0.4	3.2
Arm fat percentage (left)	0.3	1.3	2.9	-1.0	0.1	1.6	1.4	-1.0	1.7	-1.1	0.3	0.8
Average weekly red wine intake	0.7	1.0	2.9	0.8	-0.3	0.3	-0.3	1.2	-1.7	1.7	-1.0	0.2
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.3	0.4	0.5	1.0	0.2	0.6	0.1	-0.1	0.1	1.2
Mood swings	0.5	0.9	2.7	0.3	-0.5	-0.3	-1.1	-1.0	1.6	-0.5	1.5	-0.3
Loneliness, isolation	1.2	1.7	5.3	-0.7	-0.2	-1.2	-2.2	0.8	-2.3	0.7	-0.2	-1.3
Long-standing illness, disability or infirmity	0.3	0.5	3.3	-0.7	0.3	1.8	0.2	0.3	-0.2	0.4	-0.4	0.5
Ever had bowel cancer screening	0.9	1.1	2.1	0.8	0.9	1.4	1.1	0.5	0.2	1.1	-1.1	1.4
Diabetes diagnosed by doctor	0.6	1.0	3.6	-1.9	1.4	0.8	1.2	0.5	-0.1	0.3	-0.3	1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	4.6	-0.9	0.5	2.1	0.5	0.1	1.0	-0.3	0.5	1.5
Friendships satisfaction	0.6	0.7	1.7	-0.4	-0.9	-0.0	-0.9	0.7	-1.3	1.1	-1.1	-0.2
Qualifications: nursing, teaching	0.4	0.7	2.2	0.2	-1.5	-0.8	-1.2	-0.7	-0.1	-0.3	0.1	-1.1
Commuting to job workplace: Walk	0.4	0.5	2.0	0.9	-1.4	-0.2	0.3	-0.5	-0.2	0.1	-0.9	-0.3
Eye problems/disorders: Cataract	0.2	0.2	0.9	-0.9	0.5	0.0	0.2	0.3	-0.3	0.2	-0.6	0.6
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.6	-1.9	-0.1	-0.0	-1.5	-0.0	0.7	-1.5	1.3	-0.8
Medication for cholesterol	0.9	1.4	3.3	-0.7	-1.3	-1.1	-0.7	-1.6	0.6	-1.8	1.0	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.2	3.3	-0.9	0.6	1.8	0.9	-0.5	1.8	-0.8	1.2	0.7
Back pain experienced in last month	0.9	1.3	3.6	0.2	1.5	1.9	1.0	0.5	1.0	0.4	1.0	1.4
Mineral and other dietary supplements	1.3	1.8	4.5	-2.0	-1.4	-2.1	-1.1	-1.0	-0.7	-0.8	-0.3	-1.4
Breast cancer (self-reported)	0.4	0.5	0.9	0.9	-0.7	-0.4	-0.7	0.1	0.3	-0.6	0.7	-1.0
Asthma (self-reported)	0.9	1.9	4.7	1.3	-1.4	-1.7	-1.3	-1.1	1.1	-0.8	0.9	-2.2
Osteoporosis (self-reported)	1.2	1.4	3.1	-0.2	1.3	0.9	-0.7	1.8	-1.7	1.6	-0.6	1.1
Osteoarthritis (self-reported)	0.7	0.9	3.1	0.7	0.6	0.8	1.8	0.1	-0.6	0.9	-1.5	0.5
Medication: Aspirin	1.3	1.7	5.3	-0.1	-1.1	-2.3	0.8	-1.4	0.6	-0.9	-0.9	-2.0
Medication: Gliclazide	0.5	0.6	2.0	-0.0	-0.6	0.8	1.2	-0.3	-0.3	0.0	-1.4	0.5
Illnesses of father: None of the above (group 1)	1.7	2.1	6.7	-0.3	1.7	1.0	0.6	1.1	-1.6	2.6	-1.4	1.5
Smoking status: Current	0.7	1.0	2.4	0.7	1.0	1.0	0.5	1.2	-0.7	1.5	0.2	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	4.0	1.2	-0.5	-0.7	-0.9	-0.5	1.3	-0.9	2.0	-1.1
Whole body water mass	1.1	6.0	14.7	-1.9	3.5	3.8	1.9	2.2	1.0	1.6	1.1	3.3
Leg predicted mass (right)	0.9	5.1	11.9	-1.9	3.0	3.5	2.1	1.8	1.0	1.5	0.4	3.1
Arm fat mass (left)	0.6	2.4	7.3	-1.2	1.6	2.7	1.7	0.1	1.7	-0.4	0.8	1.9
Number of self-reported non-cancer illnesses	0.3	0.4	1.0	1.0	-0.9	-0.5	-0.1	-0.8	0.7	-0.2	-0.0	-0.8
Average weekly champagne plus white wine intake	0.7	0.9	2.3	-1.5	0.2	0.1	1.0	0.6	-1.1	0.7	-1.5	-0.7
Miserableness	0.5	0.8	2.3	-1.0	1.5	0.0	-1.0	0.8	0.0	0.2	1.3	0.8
Guilty feelings	1.2	1.7	4.8	-0.4	0.3	-1.6	-1.8	-1.1	0.3	-1.2	2.2	-1.4
Wears glasses or contact lenses	0.3	0.4	1.1	1.0	-0.2	0.7	-0.0	-0.1	1.0	-0.7	0.5	0.2
Ever taken oral contraceptive pill	0.3	0.4	2.0	-0.1	-0.4	-0.4	-0.9	-0.1	-0.2	0.1	1.4	0.2
Hearing aid user	0.8	0.9	4.9	2.2	0.7	0.2	1.2	0.0	0.8	0.7	-0.0	0.6
Mother’s age at death	0.8	1.0	2.6	-0.1	-1.3	-0.4	-0.6	-1.1	1.6	-1.0	1.4	-0.2
Financial situation satisfaction	0.7	0.9	2.9	-0.7	-0.8	-1.3	-0.7	-0.6	-1.1	0.0	-0.4	-1.7
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.2	-1.0	0.0	0.0	-0.5	-0.3	0.5	-0.8	1.1	0.1
Commuting to job workplace: Public transport	1.4	1.7	5.6	1.5	-0.2	-0.8	-2.4	0.8	-1.7	1.0	-0.2	-1.4
Eye problems/disorders: Glaucoma	0.8	0.9	2.8	-1.2	0.0	-0.8	1.1	-0.4	0.4	-1.1	-0.8	-1.7
Medication: Blood pressure	0.2	0.3	1.0	1.0	0.2	0.7	0.6	-0.1	0.9	0.5	0.1	0.2
Pain type(s) experienced in last month: Hip pain	1.0	1.3	3.2	1.2	1.2	1.8	0.8	-0.6	1.6	-0.3	1.2	0.5
Supplements: Fish oil (including cod liver oil)	1.2	1.6	6.4	2.5	0.9	1.2	1.2	-0.1	1.6	0.0	0.8	0.8
High cholesterol (Self-reported)	0.9	1.5	4.4	-1.8	-0.7	-1.8	0.1	-0.8	0.2	-1.4	-0.1	-2.1
Medication: Bendroflumethiazide	0.8	1.2	3.8	-0.7	-0.7	-0.1	-2.0	-0.8	1.1	-1.0	1.7	-0.7
Medication: Paracetamol	0.1	0.2	0.5	0.6	0.2	0.1	-0.2	0.1	0.7	0.6	0.5	-0.6
Medication: Lisinopril	0.9	1.1	2.4	1.0	-0.3	-0.3	-0.4	-1.5	1.6	-1.3	1.1	-1.0
Medication: Atorvastatin	0.9	1.1	6.1	-2.5	-0.1	-0.6	-0.3	-0.3	-0.2	-1.2	0.2	-1.4
Illnesses of father: High blood pressure	0.3	0.4	1.2	-1.1	0.4	-0.7	0.6	0.3	-0.0	-0.2	-0.3	-1.1
Alcohol drinker status: Never	0.8	0.9	3.2	-0.4	-1.0	-1.2	-0.0	-1.8	1.2	-0.6	-0.1	-0.7
Ever smoked	0.3	0.5	1.8	1.3	0.3	0.5	0.4	0.6	0.3	0.9	-0.0	1.0
Basal metabolic rate	1.1	6.0	15.2	-1.6	3.5	3.9	1.9	2.0	1.2	1.5	1.2	3.3
Leg fat percentage (left)	0.5	1.9	5.9	0.3	0.9	2.4	1.4	-0.5	2.1	-0.7	1.1	1.3
Arm fat-free mass (left)	1.2	6.3	16.8	-1.4	3.8	4.1	1.8	2.2	1.0	1.6	1.3	3.3
Number of operations (self-reported)	0.6	1.0	5.2	0.3	-0.1	0.4	0.8	-0.5	2.3	-0.9	1.1	-0.4
Average weekly beer plus cider intake	0.3	0.4	1.3	-0.0	1.1	0.4	0.3	0.1	0.9	-0.1	0.5	1.1
Irritability	1.1	1.8	3.8	0.7	-1.1	-1.2	-1.0	-1.5	1.4	-1.5	1.3	-1.9
Risk taking	0.1	0.2	1.0	-1.0	0.3	-0.4	0.4	-0.2	0.1	-0.5	-0.2	-0.3
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.7	1.3	-0.6	0.7	0.9	-0.6	0.8	-0.1	-0.0	0.4
Fractured/broken bones in last 5 years	1.0	1.3	3.1	0.5	0.6	0.0	0.9	1.1	-1.8	1.0	-1.5	1.5
Age started oral contraceptive pill	0.3	0.4	1.3	0.5	0.6	-0.3	-0.7	1.1	-0.0	0.5	0.6	0.7
Diastolic blood pressure, automated reading	0.5	1.6	6.7	2.6	0.1	1.5	-0.2	-0.5	1.6	-0.7	1.4	-0.4
Ever depressed for a whole week	0.2	0.2	1.4	1.2	0.5	-0.0	-0.1	0.3	-0.3	0.0	-0.0	0.3
Unable to work because of sickness or disability	1.0	1.3	3.0	-0.2	-1.6	-0.9	-0.9	-1.7	0.7	-1.1	0.4	-1.5
Commuting to job workplace: Cycle	0.1	0.2	0.7	-0.9	0.2	-0.2	-0.2	0.3	0.3	-0.1	0.1	0.6
Myopia	0.7	1.0	2.4	1.3	-1.3	-1.2	-1.2	-0.4	0.1	-0.0	-0.2	-1.6
Vascular/heart problems diagnosed by doctor	0.7	1.9	3.2	-1.1	1.4	1.1	0.3	1.7	-1.8	1.5	-1.4	1.4
Cholesterol lowering medication	0.7	1.0	4.7	-0.9	1.4	0.3	2.2	0.5	0.1	0.3	-1.0	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.5	1.0	-0.7	-0.7	0.2	-1.6	0.4	-0.2	-0.5	-0.8
Pain experienced in last month	2.3	3.9	7.3	0.7	-2.6	-2.6	-0.3	-2.7	0.7	-2.7	0.0	-2.4
Supplements: Calcium	0.4	0.4	1.9	0.4	0.1	0.7	0.4	-0.6	1.4	-0.4	0.8	0.1
Basal cell carcinoma (self-reported)	0.2	0.2	0.5	-0.6	-0.2	0.2	-0.7	0.4	-0.7	0.5	-0.4	0.3
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.3	-0.6	-0.3	-1.1	0.4	-0.7	0.9	-0.9	0.3	0.1
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.5	0.2	-0.9	-0.9	-0.6	-1.0	1.1	-0.5	0.0	-1.2
Heart disease (siblings)	1.2	1.5	3.9	0.2	1.8	1.3	0.7	2.0	-1.0	1.1	-0.5	1.0
Alcohol drinker status: Previous	0.4	0.4	1.6	1.3	1.0	0.1	-0.3	0.3	-0.9	0.6	-0.3	0.1
Pack years of smoking	0.5	0.7	2.1	-0.9	0.7	-0.5	0.3	-0.2	0.9	-1.2	1.4	-0.8
Impedance of whole body	1.2	6.0	13.1	3.6	-3.4	-3.2	-2.4	-1.7	-0.5	-1.1	-0.3	-3.0
Leg fat mass (left)	0.8	3.1	10.0	-0.0	1.8	3.2	1.9	0.2	2.3	-0.1	1.1	2.2
Arm predicted mass (left)	1.2	6.0	16.3	-1.4	3.6	4.0	1.5	2.2	1.1	1.4	1.5	3.3