TWAS hub - LRRC58

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0780	0.0330	0.00260	0.034	NA	0.051	NA	0.040	7.8e-04	NA	5.4e-05	NA	3.2e-04
2	GTEx	Brain Hippocampus	0.3502	0.1139	0.00059	-0.002	NA	0.003	NA	-0.012	3.7e-01	NA	2.7e-01	NA	8.6e-01
3	GTEx	Muscle Skeletal	0.0687	0.0262	0.00032	0.022	NA	0.028	NA	0.017	2.6e-03	NA	7.7e-04	NA	7.2e-03
4	GTEx	Pituitary	0.2860	0.1140	0.00720	0.000	NA	0.006	NA	0.029	3.1e-01	NA	2.2e-01	NA	6.2e-02
5	NTR	Blood	0.0218	0.0099	0.00280	-0.001	0.005	0.000	0.006	0.000	6.7e-01	5.9e-03	2.3e-01	4.8e-03	2.8e-01
6	YFS	Blood	0.1247	0.0261	0.00000	0.142	0.114	0.137	0.141	0.140	4.5e-44	2.7e-35	1.1e-42	9.2e-44	1.7e-43
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0383	0.0210	0.00310	0.002	0.007	0.003	NA	0.000	2.0e-01	4.4e-02	1.4e-01	NA	3.4e-01
8	TCGA	Lung Squamous Cell Carcinoma	0.0209	0.0126	0.00750	0.018	0.007	0.003	NA	0.010	3.1e-03	4.8e-02	1.5e-01	NA	2.4e-02
9	TCGA	Prostate Adenocarcinoma	0.0326	0.0189	0.00210	0.009	0.025	0.021	NA	0.016	3.6e-02	9.8e-04	2.4e-03	NA	6.9e-03
10	TCGA	Testicular Germ Cell Tumors	0.1530	0.0770	0.00010	0.091	0.094	0.107	NA	0.103	4.0e-04	3.3e-04	1.3e-04	NA	1.8e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	3	4	5	6	7	8	9	10
Hearing difficulty/problems: Yes	3.2	4.9	12.0	1.1	0.4	2.8	2.2	-3.4	3.5	1.0	2.9	1.1
Had menopause	2.6	3.3	12.0	-0.6	-3.5	1.1	0.4	-0.4	1.8	3.1	-1.3	-2.0
Medication: Lisinopril	2.5	3.2	9.5	1.7	3.1	1.5	2.0	-1.5	-0.7	-1.6	2.2	1.9
Illnesses of father: High blood pressure	2.4	3.0	9.9	3.1	1.2	-0.2	1.1	-1.8	1.3	-0.7	2.5	2.4
Frequency of tenseness / restlessness in last 2 weeks	2.3	3.6	10.2	0.8	-0.9	1.2	1.5	-2.9	3.2	3.1	1.1	-1.1
Number of live births	2.2	3.1	8.3	-0.2	-1.7	-2.1	-0.4	1.0	0.5	2.9	-2.6	-2.6
Illnesses of mother	2.1	2.6	13.7	-3.7	1.8	-1.1	-0.5	0.5	-1.9	-0.7	-0.9	-1.7
Commuting to job workplace: Cycle	2.1	2.6	7.8	2.8	1.0	0.9	1.5	-1.0	0.2	-1.3	2.0	2.6
Illnesses of father: Heart disease	2.0	2.8	10.2	0.7	0.9	2.3	0.4	-0.1	0.2	-2.6	2.0	3.2
Had other major operations	1.8	2.2	9.3	-0.5	-2.0	0.4	-0.7	-0.2	1.2	3.1	-1.5	-2.0
Medication: Atorvastatin	1.8	2.2	5.6	2.0	1.2	0.2	1.4	-2.1	1.1	-0.8	2.4	1.6
Comparative height size at age 10	1.7	9.4	27.8	-5.3	-1.3	1.2	-3.4	4.1	-4.0	-2.0	-3.4	-1.8
Type 2 Diabetes (T2D) (2012)	1.6	1.9	5.3	1.9	1.0	-0.5	0.8	-1.1	0.2	-1.7	2.0	2.3
Hand grip strength (right)	1.6	4.3	9.1	-3.0	-1.6	2.3	-2.2	1.5	-0.6	2.1	-2.9	-2.5
Birth weight	1.6	3.5	16.5	-4.1	-1.7	1.2	-1.1	1.5	-1.5	0.3	-2.1	-2.0
Crohns Disease (2012)	1.5	2.4	9.9	-0.0	-2.0	0.9	0.9	-1.1	2.4	3.1	-0.4	-1.2
Hand grip strength (left)	1.5	4.0	9.3	-3.1	-2.1	2.3	-1.0	1.3	0.1	2.4	-2.7	-2.4
Diverticular disease/diverticulitis (self-reported)	1.5	1.8	6.5	-0.8	-0.1	-0.7	-0.9	1.9	-2.5	-0.7	-1.9	-1.5
Chronic bronchitis/emphysema (father)	1.5	1.8	8.7	-2.9	-0.4	-1.7	-0.4	1.1	0.1	0.8	-1.5	-1.3
Age at last live birth	1.5	2.2	7.1	1.3	-2.1	1.5	1.0	0.8	1.1	2.7	-1.7	-1.0
Leg pain on walking	1.5	1.8	5.2	-0.7	-1.1	-0.9	-2.1	2.3	-1.4	-0.4	-1.9	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.7	4.8	-1.5	0.5	1.1	2.1	-2.2	1.0	1.0	1.1	-0.9
Illnesses of father: None of the above (group 1)	1.5	1.8	5.5	-1.4	-1.3	-1.4	-0.1	0.9	-1.1	1.1	-1.9	-2.3
Average weekly beer plus cider intake	1.5	2.2	4.9	-1.2	-2.2	-1.9	-1.7	2.0	-0.2	0.3	-1.9	-1.2
Pack years of smoking	1.5	2.1	10.1	-0.3	3.2	-1.0	-0.1	-0.2	-1.2	-2.3	1.3	1.3
Crohns Disease (2017)	1.4	3.1	11.7	1.2	-2.2	0.5	0.6	-1.6	2.7	3.4	-0.3	-1.6
Ovarian Cancer	1.4	1.9	4.8	2.2	2.2	-1.1	-0.2	-0.5	-0.3	-1.2	1.4	2.1
Eye problems/disorders: Diabetes related eye disease	1.4	1.6	10.3	3.2	0.6	-0.4	1.0	-0.6	0.2	-0.9	1.2	1.2
Number of full brothers	1.4	1.7	5.6	-2.4	-0.8	-0.8	-1.2	1.8	-0.9	0.9	-1.9	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	4.5	-0.8	-0.0	0.2	1.8	-2.1	2.0	1.2	1.3	-0.5
Risk taking	1.4	2.0	9.2	3.0	-1.6	0.4	0.3	0.5	1.4	0.9	0.2	2.2
Lung FVC	1.3	6.5	24.8	5.0	0.0	1.8	2.6	-2.0	2.8	-0.0	2.8	3.1
Diabetes (father)	1.3	1.6	5.1	1.6	0.4	-0.5	1.8	-1.7	2.2	0.9	1.1	-0.2
Severe depression (siblings)	1.3	1.5	4.5	-0.6	-1.9	2.1	0.4	-0.6	1.6	1.8	0.1	-0.1
Pack years adult smoking proportion	1.3	2.1	9.9	0.2	3.1	-0.9	-0.2	-0.3	-0.9	-2.2	1.4	1.5
Maternal smoking around birth	1.3	1.9	9.5	-0.1	0.7	-0.3	-3.1	1.8	-1.8	-0.9	-1.3	-0.4
Hearing difficulty/problems with background noise	1.3	2.0	5.7	0.2	0.8	1.1	1.3	-1.6	2.0	-0.5	2.4	2.1
Diabetes (self-reported)	1.3	2.0	6.3	2.5	1.7	-0.0	1.3	-1.5	0.5	-1.0	2.0	1.2
Exposure to tobacco smoke outside home	1.3	1.7	6.1	-0.5	0.7	-0.7	-2.5	0.6	-1.9	-2.3	0.1	0.2
Hearing aid user	1.3	1.5	5.5	0.7	1.7	2.3	1.2	-0.9	0.3	-0.9	1.4	1.1
Chronotype (morning person)	1.2	2.8	13.5	-1.4	2.3	-3.7	-0.2	1.3	-1.7	-1.6	-0.5	0.2
Medication: Aspirin	1.2	1.6	5.4	0.6	1.5	0.5	1.1	-0.8	-0.7	-2.3	1.7	1.4
HbA1C	1.1	1.3	6.9	-0.1	0.4	-2.6	1.4	-0.6	0.5	-0.3	1.0	1.3
Sensitivity / hurt feelings	1.1	1.9	9.1	-2.7	1.0	-3.0	-0.9	-0.1	-0.1	-0.2	0.0	-1.0
Pain all over the body in last month	1.1	1.2	4.4	2.1	-0.8	0.9	0.5	-0.8	1.3	0.4	1.1	1.4
Father’s age at death	1.1	1.4	5.1	-0.3	-2.3	1.0	0.8	-0.3	1.3	2.0	-0.6	-1.2
Diabetes diagnosed by doctor	1.1	1.8	4.5	2.1	1.9	0.7	1.5	-1.2	-0.1	-1.4	1.7	1.0
Mouth/teeth dental problems: Mouth ulcers	1.1	1.7	9.2	-0.3	1.0	0.3	-0.1	1.0	-0.8	-2.1	1.0	3.0
Financial situation satisfaction	1.1	1.4	3.6	-1.5	-0.2	1.1	0.4	-1.9	1.6	1.7	0.7	-0.9
Alzheimer’s Disease (in father)	1.0	1.1	3.2	-0.2	-0.9	1.3	-1.8	0.9	-1.3	0.3	-1.2	-1.1
Lupus	1.0	1.5	6.9	1.6	0.8	0.4	-1.0	0.8	-0.5	-1.5	0.8	2.6
Type 2 Diabetes (T2D) (2018)	1.0	1.8	4.1	1.6	1.8	1.6	2.0	-1.4	0.2	-0.9	1.6	0.8
Leg fat-free mass (left)	1.0	5.3	23.2	-4.8	0.6	1.2	-2.4	1.7	-2.4	-0.5	-2.2	-2.8
Hayfever, allergic rhinitis or eczema	1.0	2.3	6.0	1.9	0.3	0.1	2.4	-1.4	1.9	-0.3	1.9	1.9
High blood pressure (mother)	1.0	1.3	2.9	1.5	0.0	1.6	1.7	-1.3	1.1	0.3	1.3	1.0
Leg predicted mass (left)	1.0	5.3	23.4	-4.8	0.5	1.2	-2.5	1.7	-2.3	-0.5	-2.2	-2.9
Allergy	1.0	2.2	7.6	-1.2	-0.2	0.5	-2.8	1.7	-2.4	-0.7	-1.6	-1.1
Noisy workplace	1.0	1.2	4.4	-2.1	-0.9	1.1	-1.2	0.7	-0.3	0.9	-1.1	-1.3
Medication: Lansoprazole	1.0	1.2	3.8	1.0	0.4	-0.4	1.0	-1.7	1.9	0.6	1.4	0.4
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	7.7	2.8	1.0	0.9	0.3	-1.2	0.0	-0.9	1.5	1.3
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	4.0	1.3	-1.4	-0.3	1.1	-0.5	2.0	2.0	0.2	0.3
Age at first live birth	1.0	1.7	6.4	0.6	-1.7	2.2	2.5	-0.1	1.4	0.8	0.2	0.4
Leg fat-free mass (right)	1.0	5.5	23.6	-4.9	0.1	1.4	-2.7	1.7	-2.2	-0.1	-2.4	-3.1
Smoking status: Current	1.0	1.7	5.4	2.3	0.4	-0.4	0.5	-1.6	1.4	-0.4	2.0	1.3
Leg predicted mass (right)	1.0	5.4	23.0	-4.8	0.1	1.4	-2.6	1.7	-2.1	-0.1	-2.3	-3.0
Prostate Cancer	0.9	1.3	4.7	0.2	-2.2	0.6	-0.1	0.9	-0.3	1.4	-1.7	-1.4
Mean Putamen Volume	0.9	1.0	3.8	-1.2	-0.6	1.6	-0.4	-0.1	-0.5	0.8	-0.8	-1.9
Ever used hormone-replacement therapy (HRT)	0.9	1.1	2.6	-1.5	-0.8	-0.3	0.3	-1.4	1.4	1.3	0.3	-1.6
Age when periods started (menarche)	0.9	2.2	7.6	1.4	0.3	-0.8	2.8	-2.0	2.0	0.8	1.6	0.6
Nervous feelings	0.9	1.7	5.9	-1.8	1.3	2.4	0.8	-1.4	1.3	0.2	1.1	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	4.3	-2.1	-0.4	1.2	-0.6	-0.8	1.1	1.3	0.1	-0.6
Mouth/teeth dental problems: Dentures	0.9	1.5	3.8	-1.2	-0.1	0.6	-0.9	-1.8	1.7	2.0	0.3	-1.4
Lung cancer (father)	0.9	1.0	3.4	0.1	-0.1	-0.1	1.4	-1.0	1.0	1.9	-0.4	-1.6
Exposure to tobacco smoke at home	0.9	1.0	4.5	2.1	1.1	-1.3	0.4	-0.7	0.6	-0.5	0.9	0.9
Birth weight of first child	0.9	1.7	9.5	-0.8	3.1	0.1	-0.4	-0.2	-1.5	-1.9	0.8	0.5
Mouth/teeth dental problems: Loose teeth	0.9	1.0	3.0	0.5	0.2	1.6	0.7	-1.7	1.2	1.2	1.0	-0.5
Alcohol intake frequency.	0.9	2.0	3.9	2.0	1.8	1.1	1.5	-1.8	0.7	-0.5	2.0	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	3.0	0.3	-0.4	0.1	1.5	-1.4	1.7	1.5	0.6	-0.8
Whole body fat-free mass	0.9	5.2	21.9	-4.7	0.2	1.4	-2.3	1.4	-2.5	-0.3	-2.2	-3.1
Loneliness, isolation	0.9	1.2	3.4	-1.0	1.3	-1.4	-1.8	0.4	-1.3	-0.3	-0.7	-1.3
Eye problems/disorders: Cataract	0.9	1.1	4.2	-0.7	-0.1	-2.0	-1.9	0.8	-0.8	0.3	-1.0	-0.2
Whole body water mass	0.9	5.2	21.3	-4.6	0.1	1.6	-2.2	1.4	-2.4	-0.2	-2.3	-3.1
Tinnitus: Yes, now most or all of the time	0.9	1.1	3.3	-1.3	-0.6	0.1	-0.4	1.1	-0.5	1.1	-1.8	-1.7
Ever depressed for a whole week	0.9	1.1	2.9	-1.1	-1.7	0.3	-0.2	-0.4	1.4	1.6	-0.6	-1.3
Respiratory disease	0.8	1.9	3.9	1.3	-1.7	-1.2	2.0	-1.0	1.8	2.0	0.0	-0.9
Lung FEV1/FVC ratio	0.8	4.0	13.0	3.0	2.0	1.0	-0.5	-0.7	0.3	-2.4	2.5	3.6
Number of treatments/medications taken	0.8	1.5	3.5	1.0	1.9	0.4	1.4	-1.1	0.4	-1.3	1.9	1.3
Medication for hormone replacement therapy	0.8	0.9	2.0	-0.1	-0.1	1.0	1.4	-1.4	1.3	0.2	1.4	0.6
Supplements: Zinc	0.8	0.9	2.6	0.3	1.4	-0.8	1.6	-0.6	0.2	-1.2	1.1	0.7
Impedance of leg (right)	0.8	4.0	12.7	2.8	0.7	-1.9	2.7	-0.5	1.0	-1.5	2.2	3.6
Current tobacco smoking	0.8	1.4	4.2	1.8	0.4	-0.2	0.1	-1.3	1.0	-1.0	2.1	1.6
Taking other prescription medications	0.8	1.2	2.9	1.1	0.8	1.1	0.8	-1.1	1.6	-0.5	1.7	1.3
Serious illness, injury or assault to yourself	0.8	0.9	2.7	0.1	1.6	-0.4	1.2	-1.1	0.2	-0.8	1.5	1.1
Impedance of leg (left)	0.8	3.9	13.6	3.0	0.1	-1.4	2.4	-0.7	1.5	-1.1	2.2	3.7
Qualifications: None of the above	0.8	1.7	6.1	-1.1	0.2	-2.5	-0.6	0.2	-0.1	1.7	-1.3	-2.0
Medication: Ramipril	0.8	1.1	3.9	-1.3	0.3	0.2	-1.0	1.6	-0.9	-2.0	-0.3	0.6
Trunk fat-free mass	0.8	4.6	18.1	-4.3	0.2	1.5	-2.1	1.2	-2.6	-0.4	-2.1	-3.0
Qualifications: A levels/AS levels or equivalent	0.8	1.8	6.6	1.8	0.6	-0.3	-0.5	0.6	-1.1	-2.2	1.0	2.6
Trunk predicted mass	0.8	4.8	19.2	-4.4	0.2	1.5	-2.2	1.3	-2.6	-0.4	-2.2	-3.0
Blood clot in the leg (DVT)	0.8	1.0	2.2	0.7	1.4	-1.5	0.6	-0.9	0.2	-1.2	1.4	0.8
Gout (self-reported)	0.8	1.1	4.2	-2.1	-1.3	-0.7	-0.4	0.4	0.5	0.9	-1.1	-1.6
Neck or shoulder pain in last month	0.8	1.1	2.5	1.0	1.6	-0.2	1.1	-0.8	-0.2	-1.3	1.6	1.3
Medication: Blood pressure	0.8	1.5	3.8	-0.5	0.9	1.2	1.8	-2.0	1.4	0.1	1.7	0.3
Medication: Allopurinol	0.8	1.1	3.4	-1.8	-1.2	-0.4	-1.3	1.1	-0.1	0.2	-1.1	-1.1
Number of full sisters	0.8	1.0	2.2	0.7	-0.7	-0.4	1.1	-1.4	1.4	1.5	0.3	-1.1
Commuting to job workplace: Car/motor vehicle	0.8	0.9	3.3	-0.3	-0.9	1.8	0.9	-0.7	1.3	1.1	0.3	-0.1
Average weekly red wine intake	0.8	1.2	6.2	2.5	0.2	0.6	0.6	-1.3	1.0	1.4	0.6	-0.0
Basal metabolic rate	0.8	4.6	18.4	-4.3	0.4	1.6	-2.4	1.5	-2.3	-0.5	-2.1	-2.7
Age started oral contraceptive pill	0.8	1.0	2.8	-0.7	-1.7	1.1	0.8	0.1	-0.1	1.4	-1.1	-1.2
Heart attack/myocardial infarction (self-reported)	0.8	1.1	3.6	-1.1	-0.2	-1.9	-1.5	0.9	-0.7	-0.3	-1.0	-1.2
Bipolar Disorder (2018)	0.7	1.2	3.7	1.9	-0.6	1.2	0.2	-1.0	1.5	1.4	0.7	0.9
Fasting Glucose	0.7	0.8	1.6	0.1	1.2	-1.1	-1.1	1.3	-1.2	-0.6	-0.9	-0.3
Rheumatoid Arthritis	0.7	0.9	3.6	-0.7	0.2	1.0	-0.9	1.0	-0.8	-1.9	0.4	1.2
Waist Hip Ratio (WHR)	0.7	3.4	9.9	3.1	-0.0	0.5	1.8	-1.6	2.0	-0.2	2.3	2.9
Relative age voice broke	0.7	1.1	2.8	-0.1	-1.5	1.7	1.3	0.3	1.3	1.5	-0.6	-0.4
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	1.9	0.1	1.4	1.1	-0.9	-1.0	-0.5	-1.2	1.2	0.3
Qualifications: CSEs or equivalent	0.7	0.9	2.7	0.7	1.6	-1.2	-0.3	-0.1	-0.5	-1.7	1.0	0.9
Stomach or abdominal pain in last month	0.7	0.9	4.3	0.4	-0.7	-0.0	0.3	-1.2	2.1	1.4	0.9	0.3
Hair/balding pattern: Pattern 2	0.7	0.9	5.1	-2.3	0.4	0.6	-1.4	0.7	-0.5	-0.4	-0.5	-0.7
Weight	0.7	3.5	10.2	-3.2	0.7	1.7	-2.6	1.9	-2.2	-1.1	-1.7	-1.5
Time employed in main current job	0.7	0.8	4.5	-1.1	-0.5	2.1	0.1	-0.5	1.2	0.3	0.6	0.1
Happiness	0.7	0.8	3.0	-1.2	1.7	0.3	-0.1	-1.1	-0.3	-1.1	1.1	-0.2
Standing height	0.7	7.1	36.7	-6.1	-0.6	0.8	-1.4	2.8	-3.2	-1.6	-2.6	-2.0
Loud music exposure frequency	0.7	0.8	1.7	-0.7	-0.6	-1.0	1.2	-1.1	1.3	0.7	0.4	-1.0
Arm fat-free mass (right)	0.7	3.8	11.5	-3.4	-0.4	1.4	-2.1	1.3	-1.9	0.5	-2.3	-3.0
Emphysema/chronic bronchitis	0.7	0.8	2.3	-1.5	-0.4	0.1	1.1	0.0	0.5	1.5	-0.7	-0.8
Migraine (self-reported)	0.7	0.9	2.3	-0.5	-0.9	1.3	-0.4	-0.9	0.8	1.5	-0.2	-1.5
Arm predicted mass (right)	0.7	3.5	12.3	-3.5	-0.6	1.5	-1.6	0.9	-1.4	0.9	-2.1	-3.1
Qualifications: nursing, teaching	0.7	1.1	6.0	0.1	0.7	2.4	1.6	-0.3	0.1	-1.0	0.8	0.8
Commuting to job workplace: Walk	0.7	0.7	2.7	1.4	0.4	-1.7	-1.4	-0.2	-0.6	-0.4	0.2	0.4
Medication: Aspirin	0.7	0.9	3.0	0.4	0.9	0.2	1.4	-0.7	-0.4	-1.7	1.3	1.0
Mother’s age at death	0.7	0.9	4.7	2.2	-0.6	-0.6	0.7	-1.0	0.8	0.8	0.6	0.2
Commuting to job workplace: Public transport	0.7	0.9	1.8	0.6	1.2	-1.3	-1.3	0.2	-0.7	-1.0	0.6	1.4
Alcohol drinker status: Never	0.7	0.8	3.3	0.3	1.0	0.2	1.8	-0.7	0.9	-0.2	1.1	0.9
Arm fat-free mass (left)	0.7	3.4	11.6	-3.4	-0.1	1.6	-1.8	1.4	-1.8	0.1	-2.1	-2.6
Number of operations (self-reported)	0.7	1.1	3.8	-0.1	-0.2	1.8	0.4	-1.5	1.2	1.9	0.2	-0.5
Worry (Nagel 2018)	0.6	1.3	4.1	-0.5	1.9	2.0	0.5	-0.0	0.0	-1.3	1.0	1.4
Irritable Bowel Disease (IBD)	0.6	1.3	5.2	0.8	-1.2	-0.2	-0.6	-0.5	1.0	2.3	-0.9	-1.9
Major Depression (MDD)	0.6	0.8	4.5	-0.4	-0.9	2.1	0.5	0.4	0.5	0.5	-0.7	-0.9
HDL Cholesterol	0.6	1.1	4.3	1.3	-1.3	2.1	0.1	0.6	0.8	1.1	-0.8	-0.1
Primary Biliary Cirrhosis	0.6	0.8	2.6	-0.9	0.6	1.4	-1.6	0.4	-1.0	-1.0	-0.1	0.4
Smoking Status	0.6	1.5	5.9	0.7	-1.0	-0.2	1.0	-1.5	2.4	1.1	1.5	0.7
Allergy or Eczema	0.6	1.6	4.3	2.1	-0.3	0.4	1.9	-1.1	1.1	-0.6	1.6	1.7
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.1	-0.8	1.3	0.2	0.7	-0.9	0.4	-1.0	1.5	1.1
Medication: Metformin	0.6	0.8	2.2	1.2	0.8	1.5	0.5	-0.5	-0.3	-1.3	1.2	0.6
Heart attack	0.6	0.8	3.5	-1.3	0.1	-1.9	-1.1	0.4	-0.5	-0.2	-0.6	-1.1
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.5	1.5	-0.7	0.0	0.3	-0.1	1.6	1.5	0.0	0.8
Impedance of arm (right)	0.6	2.7	11.0	-0.3	1.1	-1.7	0.5	1.2	-1.1	-3.3	1.1	2.7
Hair/balding pattern: Pattern 3	0.6	0.8	4.7	2.2	-0.4	0.3	-1.0	0.8	-1.1	-0.7	-0.4	0.3
Asthma	0.6	1.2	3.9	1.0	-0.3	-0.8	2.0	-1.3	1.7	1.0	0.9	0.2
Prospective memory result	0.6	0.8	3.1	0.2	0.4	0.1	-0.9	0.8	-0.7	-1.8	0.6	1.5
Length of working week for main job	0.6	0.6	1.6	-0.8	-1.1	-1.3	-0.6	0.6	0.0	0.9	-0.9	-0.7
Hair/balding pattern: Pattern 4	0.6	1.3	5.8	-0.0	-1.1	-0.9	1.2	-0.7	1.6	2.4	-0.5	-1.0
Wheeze or whistling in the chest in last year	0.6	1.2	2.7	0.0	1.2	-1.2	1.4	-1.4	1.3	1.6	0.5	-0.6
Health satisfaction	0.6	0.8	2.1	0.8	1.4	0.8	0.3	-0.5	-0.2	-1.3	1.2	1.3
Angina (self-reported)	0.6	0.7	3.4	1.3	0.6	-1.9	-1.1	0.1	-0.6	-0.2	-0.1	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.5	0.5	-1.6	-0.2	0.4	0.2	0.1	1.3	-1.0	-1.3
Supplements: Vitamin C	0.6	0.7	2.2	-1.0	1.5	0.4	1.1	-1.2	-0.6	-0.2	0.7	-0.4
Long-standing illness, disability or infirmity	0.6	0.9	3.0	0.4	1.7	-0.0	0.7	-1.3	0.6	-0.4	1.6	0.9
Asthma (self-reported)	0.6	1.3	3.9	0.9	-0.5	-0.9	2.0	-1.5	1.7	1.0	0.9	-0.0
Medication: Gliclazide	0.6	0.7	2.7	0.4	0.6	1.3	0.1	0.5	-1.2	-1.6	-0.0	-0.3
Guilty feelings	0.6	0.9	5.0	-0.3	1.4	-2.2	0.1	-0.7	0.1	-0.6	0.6	-0.4
Medication: Bendroflumethiazide	0.6	0.8	2.7	0.6	1.6	-0.9	-0.1	-1.2	-0.4	-0.9	1.3	0.8
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.0	0.6	1.1	-1.1	0.8	-1.1	0.6	-0.8	1.4	0.5
Bipolar Disorder or Schizophrenia	0.5	1.1	6.0	1.5	0.1	0.4	-0.5	-0.4	0.9	-0.1	1.2	2.4
Schizophrenia (2018)	0.5	1.0	6.0	0.4	0.7	-0.5	-0.8	0.3	-0.0	-1.3	1.0	2.5
Alzheimer’s Disease (in mother)	0.5	0.6	1.9	1.4	0.1	0.8	0.4	-1.0	0.8	0.2	1.0	0.7
Alzheimer’s Disease (including proxy)	0.5	0.7	3.8	0.9	-0.9	1.9	-0.6	-0.4	0.6	0.9	0.2	0.1
Age at First Birth	0.5	0.8	2.8	1.7	-1.1	1.0	0.6	0.8	-0.3	-0.7	-0.0	1.1
Heel T-Score	0.5	3.7	12.0	-1.1	2.1	-1.3	-1.1	2.4	-3.0	-3.5	-0.9	0.6
Height	0.5	10.6	38.8	-6.2	-2.0	0.2	-2.4	3.8	-3.6	-0.7	-4.1	-3.6
Hypothyroidism (self reported)	0.5	1.2	3.3	-0.9	-1.6	1.8	0.5	0.8	1.3	1.1	-1.0	-0.3
Angina	0.5	0.7	3.0	1.5	0.8	-1.7	-0.9	-0.1	-0.4	-0.2	0.2	0.5
Diabetes (mother)	0.5	0.7	3.1	1.8	-0.2	0.9	-0.3	0.4	0.1	-0.4	0.4	1.5
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.9	0.6	0.0	0.3	0.3	-1.1	1.4	1.1	0.8	0.5
Trunk fat mass	0.5	2.3	5.9	-1.9	0.9	1.5	-2.4	1.7	-1.8	-1.9	-0.8	-0.1
Alcohol usually taken with meals	0.5	0.9	2.6	1.6	0.3	1.2	0.5	-1.2	0.7	0.2	1.2	0.9
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.6	-1.6	-1.4	-0.2	0.5	0.1	0.2	0.3	-0.5	-1.0
Mouth/teeth dental problems	0.5	0.7	2.8	0.5	0.5	-0.2	-0.1	1.0	-1.7	-1.7	-0.3	0.4
Depression (self-reported)	0.5	0.5	2.3	0.2	1.5	-0.6	-0.1	-1.3	0.1	0.8	0.4	-0.6
Arm fat mass (right)	0.5	2.0	5.9	-1.4	1.3	1.7	-2.4	1.3	-1.6	-1.7	-0.6	-0.1
Breastfed as a baby	0.5	0.7	2.6	-1.0	0.1	0.4	-0.2	0.5	-0.0	-1.6	0.6	1.5
Glaucoma (self-reported)	0.5	0.6	1.7	1.3	0.2	1.1	1.2	0.1	0.4	-0.6	0.4	0.9
Chronic bronchitis/emphysema (mother)	0.5	0.6	3.4	-1.8	-0.4	-0.6	-0.2	-0.0	-0.1	0.6	-0.5	-1.3
Eye problems/disorders: None of the above	0.5	0.6	1.7	-0.8	-0.6	0.7	1.3	-0.9	1.0	0.3	0.7	-0.2
Overall health rating	0.5	1.0	3.6	1.3	1.9	-0.4	0.8	-1.1	0.5	-0.2	1.3	0.7
Smoking status: Previous	0.5	0.8	6.3	-2.5	0.3	0.1	0.4	-0.2	0.8	0.7	0.0	-0.1
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.6	-0.5	-1.3	1.6	-0.1	1.0	0.3	0.5	-0.6	0.4
Osteoporosis (self-reported)	0.5	0.7	2.4	-0.0	1.5	-0.3	0.3	-0.5	-0.9	-1.3	0.9	0.8
Arm fat mass (left)	0.5	2.0	6.8	-1.6	1.1	1.6	-2.6	1.3	-1.5	-1.4	-0.8	-0.5
Average weekly champagne plus white wine intake	0.5	0.7	2.5	-0.3	0.8	-0.1	-1.2	0.8	-1.3	-1.6	-0.0	0.7
Eye problems/disorders: Glaucoma	0.5	0.5	2.8	0.9	0.5	0.2	1.7	-0.7	0.6	-0.2	0.7	0.4
Ever smoked	0.5	0.8	2.5	-0.9	0.2	0.1	1.5	-0.6	1.6	0.1	1.1	1.1
Irritability	0.5	0.8	3.8	-0.2	0.2	1.9	0.7	-1.1	1.1	0.8	0.6	-0.3
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.8	0.8	0.2	-0.1	0.1	-0.6	0.6	-0.4	1.2	1.7
Unable to work because of sickness or disability	0.5	0.6	2.3	1.5	0.5	-1.5	-0.2	-0.5	0.6	0.5	0.5	0.4
Cholesterol lowering medication	0.5	0.7	3.0	1.7	0.5	0.3	1.3	0.4	0.5	-0.5	0.2	1.3
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.3	0.9	-0.6	-0.6	0.9	-1.1	0.9	0.6	0.8	-0.2
Supplements: Calcium	0.5	0.5	2.6	1.6	0.8	-0.3	0.9	-0.2	0.3	-0.0	0.4	0.8
Arm predicted mass (left)	0.5	2.6	10.6	-3.3	0.2	1.4	-1.5	1.0	-1.6	-0.1	-1.6	-2.2
Bipolar Disorder (2011)	0.4	0.4	1.3	0.6	-0.6	-0.2	0.3	-0.6	0.9	1.1	0.3	0.6
Body Mass Index (BMI) (2010)	0.4	0.6	3.1	-1.8	-0.5	-0.6	-1.2	-0.1	0.1	0.5	-0.2	-0.4
Schizophrenia (2014)	0.4	1.0	4.8	1.0	-0.1	0.8	-0.2	-0.6	1.2	0.1	1.2	2.2
Blood Eosinophil Count	0.4	3.2	11.0	-3.3	1.9	-2.6	-0.2	0.1	-2.0	-1.8	-0.3	-1.7
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.1	0.7	-0.8	-0.9	-1.1	-0.3	0.6	0.9	-0.2	-0.9
Ever had hysterectomy (womb removed)	0.4	0.5	2.7	1.6	-0.2	0.1	-0.8	0.8	-0.5	0.2	-0.7	-0.1
Trunk fat percentage	0.4	1.5	4.2	-0.8	1.0	1.1	-1.9	1.4	-1.1	-2.0	-0.1	0.9
Townsend deprivation index at recruitment	0.4	0.6	1.9	-0.1	1.2	-1.1	-0.4	0.5	-1.4	-0.7	-0.4	-0.4
Multivitamins +/- minerals	0.4	0.6	3.4	0.7	0.3	0.1	-1.8	0.3	-0.8	-0.8	0.2	0.6
Medication: Atenolol	0.4	0.4	1.3	-0.5	1.2	0.7	0.2	-1.2	-0.2	-0.3	0.9	-0.3
Sitting height	0.4	3.0	15.5	-3.9	0.2	1.6	-1.2	1.3	-2.1	-1.1	-1.3	-1.3
Past tobacco smoking	0.4	0.7	3.0	1.7	-0.7	-0.3	-1.0	0.6	-1.2	-0.3	-0.7	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	5.5	-0.5	0.8	-0.4	-0.7	0.9	-1.0	-2.3	0.5	1.0
Arm fat percentage (right)	0.4	1.6	4.4	-0.7	1.5	1.4	-2.1	1.1	-1.1	-2.0	0.0	0.7
Hip circumference	0.4	1.9	5.7	-2.4	0.0	0.5	-2.1	1.1	-1.1	0.1	-1.6	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.1	-0.5	-0.1	1.2	0.1	-1.0	1.4	0.2	1.0	0.6
Pulse wave reflection index	0.4	0.5	1.4	-1.1	0.6	-0.8	-0.4	0.2	-1.2	-1.0	-0.2	-0.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.7	0.8	-0.9	-0.9	-0.6	1.1	-0.6	0.6	-1.3	-0.4
Qualifications: College or University degree	0.4	1.1	4.2	0.3	-1.4	1.3	0.0	1.3	-0.5	-1.3	0.0	2.0
Mean time to correctly identify matches	0.4	0.7	2.9	0.1	-0.3	1.6	-1.7	0.3	-0.5	0.8	-0.6	-0.6
Heart disease (mother)	0.4	0.5	2.8	1.7	0.4	-0.8	0.8	0.1	0.1	-0.4	0.4	0.9
Whole body fat mass	0.4	1.8	5.7	-1.6	0.8	1.3	-2.4	1.6	-1.5	-1.4	-0.9	-0.4
Leg fat mass (right)	0.4	1.4	4.0	-1.3	0.8	1.4	-2.0	1.3	-1.3	-0.9	-1.0	-0.7
Had major operations	0.4	0.5	1.9	-0.5	1.4	0.1	0.6	-0.9	-0.5	-0.5	0.8	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	5.1	-2.3	1.3	0.4	0.8	0.2	-0.4	-0.9	0.2	0.3
Arm fat percentage (left)	0.4	1.5	5.8	-0.7	1.0	1.4	-2.4	1.2	-1.1	-1.6	-0.3	0.2
Ever had bowel cancer screening	0.4	0.5	2.3	0.8	1.0	0.3	-1.5	-0.8	0.2	0.3	0.4	-0.1
Friendships satisfaction	0.4	0.5	2.3	-1.5	0.4	-0.7	-0.2	0.4	-0.9	-0.1	-0.7	-0.6
Back pain experienced in last month	0.4	0.7	1.8	-0.8	-0.4	-1.1	-0.4	1.0	-0.2	0.9	-1.3	-0.9
Mineral and other dietary supplements	0.4	0.5	1.6	0.6	-0.5	-1.1	0.5	-0.4	1.1	1.3	-0.1	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	1.0	2.5	1.4	-0.4	1.3	1.0	0.2	-0.2	-1.3	0.7	1.6
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.9	-0.1	0.1	0.2	-1.0	0.8	-1.4	-0.8	-0.7	-0.7
High cholesterol (Self-reported)	0.4	0.8	2.7	0.3	0.4	0.2	-0.3	1.6	-1.4	-1.3	-0.8	0.7
Pain experienced in last month	0.4	0.6	1.7	0.1	0.7	1.0	-0.1	-0.4	-0.2	-1.3	1.1	1.3
Impedance of whole body	0.4	2.1	8.5	1.1	0.1	-1.9	1.2	0.9	0.1	-2.0	1.0	2.9
Ulcerative Colitis (UC)	0.3	0.5	1.5	0.5	0.7	-0.7	-1.1	-0.1	-0.6	0.3	-0.6	-1.2
Reaction Time	0.3	0.6	3.1	-0.5	-0.0	1.8	-1.4	0.4	-0.7	0.3	-0.3	-0.4
Coronary Artery Disease (CAD)	0.3	0.4	2.0	-1.1	-0.1	1.4	-0.2	0.3	-0.1	0.4	-0.5	-0.2
LDL Cholesterol	0.3	0.4	1.6	-0.6	-0.7	0.4	-0.3	-0.3	0.6	1.1	-0.6	-1.2
Triglycerides	0.3	0.5	2.4	-1.0	-0.1	-0.3	-0.5	-0.1	-0.2	0.9	-0.9	-1.6
Ulcerative Colitis	0.3	0.5	2.3	0.3	0.3	0.2	-1.0	0.1	-0.8	0.2	-0.7	-1.5
BMI	0.3	1.6	5.8	0.2	2.4	1.8	-1.8	-0.1	-0.5	-1.5	0.7	0.6
Systolic blood pressure, automated reading	0.3	1.0	4.6	2.2	-0.2	-0.1	-0.9	1.3	-0.2	0.1	-0.6	1.4
Vitamin and mineral supplements	0.3	0.4	1.2	-0.3	-1.1	-0.6	0.8	0.1	0.5	0.7	-0.5	-0.7
Medication: Co-codamol	0.3	0.3	2.2	0.4	0.5	1.5	0.3	0.5	0.3	-0.2	-0.1	0.6
Average weekly fortified wine intake	0.3	0.4	1.4	0.6	0.5	0.5	0.6	0.2	-0.2	-0.9	0.5	1.2
Fed-up feelings	0.3	0.5	1.9	0.4	1.4	-0.4	-0.3	-0.7	-0.1	-1.0	1.1	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.8	4.2	-0.6	0.3	-0.4	-0.7	1.0	-1.0	-2.0	0.1	0.5
Body mass index (BMI)	0.3	1.1	5.2	-0.6	1.2	1.2	-2.3	0.7	-0.9	-0.7	-0.5	-0.6
Fluid intelligence score	0.3	0.7	4.2	-0.1	-0.6	0.7	2.1	-0.3	0.8	0.8	-0.1	-0.5
Neuroticism score	0.3	0.6	2.4	-1.4	1.5	0.7	-0.4	-0.5	-0.1	-0.5	0.6	-0.2
Falls in the last year	0.3	0.4	1.3	0.5	0.7	-1.1	-0.6	-0.2	-0.9	-0.7	0.0	-0.4
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	3.7	0.2	0.3	1.3	0.0	0.6	-0.3	-1.6	0.7	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	4.6	1.0	-0.2	1.6	0.8	0.3	0.7	-1.0	0.9	2.1
Impedance of arm (left)	0.3	1.4	4.8	-0.8	0.1	-1.5	0.0	1.4	-0.8	-2.2	0.3	1.8
Peak expiratory flow (PEF)	0.3	0.8	4.6	-0.8	-0.8	2.1	0.2	0.9	0.1	-0.6	-0.1	1.0
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.9	-0.8	-0.9	0.6	-0.4	1.4	0.4	-0.0	-1.0	-0.0
Medication: Amlodipine	0.3	0.4	2.2	-0.7	-0.0	1.5	0.1	-0.8	0.5	0.4	0.4	-0.4
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.5	1.0	-0.1	-0.0	1.2	-0.5	0.5	-0.3	0.6	0.4
Body fat percentage	0.3	1.0	3.2	-0.6	0.9	1.1	-1.8	1.2	-0.9	-1.5	-0.2	0.5
Worry too long after embarrassment	0.3	0.4	1.1	-1.1	0.5	0.5	0.6	-0.5	-0.2	-1.1	0.8	0.4
Number of children fathered	0.3	0.3	1.0	-0.1	0.0	0.7	0.5	-0.5	0.5	1.0	-0.3	-0.9
Medication: Ibuprofen	0.3	0.4	1.3	-0.4	-0.3	0.6	0.4	-1.0	0.1	-0.8	1.1	0.5
Medication: Omeprazole	0.3	0.4	1.8	-0.2	-0.6	-0.2	0.4	-0.8	0.2	0.8	0.0	-1.3
Suffer from ‘nerves’	0.3	0.5	2.0	-0.9	0.5	1.4	-0.7	-0.7	0.4	-0.3	0.7	0.2
Family relationship satisfaction	0.3	0.4	1.5	-0.4	1.2	0.4	-0.3	-0.1	-0.7	-1.1	0.5	0.4
Knee pain experienced in last month	0.3	0.5	1.9	-0.4	1.1	-1.4	-0.0	-0.6	-0.8	-0.6	0.3	-0.4
Mood swings	0.3	0.6	2.9	0.0	0.2	1.7	-1.7	0.5	-0.4	-0.3	-0.2	-0.0
Miserableness	0.3	0.5	3.3	1.8	-0.7	-0.2	-0.6	0.5	0.0	0.4	-0.4	0.2
Wears glasses or contact lenses	0.3	0.3	1.1	0.9	-1.0	0.0	-0.1	-0.4	0.8	0.2	0.2	-0.1
Ever taken oral contraceptive pill	0.3	0.4	0.9	-0.1	0.3	-0.5	-0.1	0.8	-1.0	-0.9	-0.0	0.9
Medication: Paracetamol	0.3	0.4	1.9	-1.0	0.5	-1.4	-0.8	0.4	-0.4	-0.2	-0.2	-0.2
Fractured/broken bones in last 5 years	0.3	0.4	1.2	-0.2	-0.8	-1.1	-0.8	0.4	-0.8	0.1	-0.6	-0.5
Myopia	0.3	0.4	2.2	1.5	0.1	-0.9	0.7	-0.3	0.6	-0.2	0.5	0.4
Basal cell carcinoma (self-reported)	0.3	0.4	1.0	-0.0	0.5	0.8	-0.8	1.0	-0.4	-0.5	-0.3	1.0
Leg fat mass (left)	0.3	1.3	4.2	-1.2	0.5	1.7	-2.1	1.2	-1.0	-0.7	-1.0	-0.7
Depressed Affect (Nagel 2018)	0.2	0.4	1.8	-0.1	0.6	0.8	-1.3	0.4	-0.8	-0.4	-0.3	-0.3
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.5	1.2	-0.1	1.2	-0.4	1.1	-0.6	-0.5	-0.6	0.5
Neuroticism (Nagel 2018)	0.2	0.5	2.6	-0.4	1.6	1.0	-0.5	0.2	-0.4	-0.8	0.3	0.5
Breast Cancer	0.2	0.5	2.2	-1.5	-0.4	-1.1	0.2	0.2	-0.3	-0.0	-0.4	-1.0
Blood Platelet Count	0.2	2.1	4.8	-0.2	2.2	-1.6	-1.9	1.4	-2.0	-1.8	-0.5	0.2
Blood Red Count	0.2	1.9	8.1	2.2	-1.2	0.7	-2.9	1.3	-0.6	0.7	-1.4	0.1
Blood White Count	0.2	1.2	3.2	-0.7	1.4	-1.1	-1.8	0.1	-1.1	-1.6	0.2	-1.2
Neuroticism	0.2	0.6	2.8	-1.0	1.7	0.7	-0.1	0.1	-0.6	-1.0	0.4	0.3
Average weekly spirits intake	0.2	0.2	1.6	-0.4	-0.1	-1.3	-0.1	-0.1	-0.1	-0.6	0.1	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.8	-0.3	-0.4	0.4	-0.2	-0.9	0.7	-0.0	0.9	-0.0
Supplements: Glucosamine	0.2	0.2	0.6	-0.4	-0.6	-0.8	-0.2	0.6	-0.4	-0.3	-0.6	-0.1
Waist circumference	0.2	0.6	2.0	-1.1	0.6	1.0	-1.4	0.6	-0.5	-0.3	-0.6	-0.5
Forced vital capacity (FVC)	0.2	0.6	2.4	-0.2	0.2	0.7	0.2	0.8	-0.8	-1.5	0.3	1.4
Financial difficulties in last 2 years	0.2	0.3	1.0	-1.0	1.0	0.6	0.1	-0.7	-0.1	0.3	0.2	-0.5
Illnesses of siblings	0.2	0.2	0.9	0.1	0.3	0.5	0.4	-0.8	-0.3	0.3	0.3	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.5	-0.6	-0.6	0.6	0.2	-0.5	0.1	-0.6	0.7	0.2
Medication: Cholesterol lowering	0.2	0.4	0.8	0.7	0.7	0.4	-0.7	-0.5	-0.3	-0.9	0.8	0.5
Tense / ‘highly strung’	0.2	0.4	2.0	-0.5	0.1	0.2	0.3	-0.0	1.4	1.2	-0.2	-0.2
Headache pain in last month	0.2	0.4	0.9	-0.9	-0.6	0.4	-0.3	1.0	0.0	0.1	-0.8	-0.8
High blood pressure (siblings)	0.2	0.3	2.3	-0.3	-0.1	-1.5	0.1	0.4	0.3	-0.3	-0.2	0.3
Forced vital capacity (FVC), Best measure	0.2	0.8	3.7	0.8	-0.3	1.0	1.0	0.5	0.6	-0.7	0.6	1.9
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.2	-0.5	-0.2	-0.2	-1.1	0.6	-0.2	-0.1	-0.4	0.2
Shortness of breath walking on level ground	0.2	0.2	0.6	0.7	0.6	0.6	0.3	-0.5	0.2	0.1	0.5	0.2
Pulse rate, automated reading	0.2	0.8	2.3	0.8	-0.3	0.9	1.4	-0.2	1.5	1.2	0.4	0.8
Chest pain or discomfort	0.2	0.3	1.1	0.8	-0.3	-0.4	0.5	-0.7	0.8	1.1	0.3	-0.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.4	0.3	0.2	1.2	-0.0	0.3	-0.6	-0.9	0.1	0.2
Illnesses of siblings: Diabetes	0.2	0.2	0.9	0.9	-0.2	0.6	-0.2	-0.1	0.3	0.4	0.2	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.7	0.4	-0.5	-0.1	-0.8	0.0	0.8	0.5	-0.1	-0.1
Medication for cholesterol	0.2	0.3	0.8	-0.6	-0.6	-0.9	0.8	-0.5	0.5	0.4	0.1	-0.8
Breast cancer (self-reported)	0.2	0.3	0.7	-0.5	-0.1	0.2	-0.9	0.6	-0.7	-0.7	-0.2	0.2
Osteoarthritis (self-reported)	0.2	0.2	1.5	1.2	0.5	-0.1	0.4	-0.3	0.3	-0.3	0.3	0.3
Number of self-reported non-cancer illnesses	0.2	0.3	1.2	-0.0	-0.3	0.2	-0.7	0.2	0.9	1.1	-0.6	-0.5
Medication: Blood pressure	0.2	0.3	2.1	-0.1	0.6	0.4	-1.5	0.2	-0.5	0.3	-0.2	0.1
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.3	0.6	-1.1	0.7	0.4	0.0	0.4	0.1	-0.0	-0.2
Diastolic blood pressure, automated reading	0.2	0.5	1.5	-0.0	-0.1	0.8	-1.2	1.1	-0.6	0.4	-1.0	0.1
Alcohol drinker status: Previous	0.2	0.2	0.8	0.4	0.6	-0.9	0.2	-0.3	0.2	0.2	0.0	-0.4
Depression (Nagel 2018)	0.1	0.1	0.3	0.4	0.4	-0.1	-0.4	-0.4	0.1	-0.0	0.6	0.2
Schizophrenia vs Biploar Disorder	0.1	0.1	0.4	-0.7	-0.1	0.1	-0.0	-0.1	-0.5	0.0	0.0	-0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.5	1.2	-0.4	0.7	0.4	0.1	0.2	0.1	-0.0	0.5
Neuroticism (2016)	0.1	0.2	1.0	-0.1	0.2	1.0	0.2	-0.1	-0.7	-0.1	-0.2	-0.3
Systolic Blood Pressure	0.1	0.7	2.4	1.6	0.7	-0.6	0.6	-0.7	0.4	-0.4	1.1	1.4
Cardiovascular Disease	0.1	0.4	1.4	0.1	0.6	-0.1	-0.7	1.2	-0.3	-0.3	-0.5	1.1
Hair Pigment	0.1	3.2	8.6	2.4	2.1	-1.4	1.2	-2.9	1.0	-0.2	2.7	1.2
Tanning	0.1	1.8	5.2	-0.0	1.1	-0.8	-1.7	1.4	-2.1	-2.3	-0.1	1.1
Relative age of first facial hair	0.1	0.3	1.1	-0.5	-0.7	0.6	-0.0	0.3	0.5	1.1	-0.6	-0.1
High blood pressure	0.1	0.3	1.3	0.0	1.1	0.2	-0.6	0.2	-0.4	-0.7	0.3	0.7
Medication: Levothyroxine sodium	0.1	0.2	0.7	-0.6	-0.4	0.9	0.3	0.3	0.7	0.2	-0.2	0.1
Number of incorrect matches in round	0.1	0.2	1.8	0.4	-0.4	-0.2	-1.4	0.3	-0.2	-0.2	0.0	0.4
Medication: Simvastatin	0.1	0.2	0.4	0.6	0.1	0.6	-0.2	0.5	-0.4	-0.3	-0.5	-0.1
Alcohol intake versus 10 years previously	0.1	0.2	0.7	0.2	-0.2	-0.3	-0.3	0.8	-0.6	-0.7	-0.2	0.6
Worrier / anxious feelings	0.1	0.3	1.3	-0.4	1.1	0.9	0.2	-0.3	0.1	-0.1	0.3	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.5	0.4	0.2	0.7	-0.6	-0.3	0.7	0.6	0.5	0.4
Pulse rate	0.1	0.2	0.6	0.2	0.1	0.6	0.8	0.3	0.6	0.4	-0.1	0.3
Pulse wave Arterial Stiffness index	0.1	0.1	0.7	0.0	0.1	0.8	0.1	-0.5	0.1	-0.4	0.4	0.2
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.6	-0.8	0.2	-0.2	-0.0	0.2	-0.1	0.1	-0.3	-0.3
Medication: Paracetamol	0.1	0.2	0.9	-0.9	0.9	-0.6	-0.4	0.2	-0.2	-0.2	0.0	0.0
Leg fat percentage (right)	0.1	0.5	1.2	0.6	0.7	0.9	-1.1	0.8	-0.5	-0.8	-0.3	0.4
Comparative body size at age 10	0.1	0.2	1.7	-0.3	-0.1	0.3	-1.3	0.2	-0.2	0.2	-0.3	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.4	-0.0	-0.0	-0.5	-0.1	0.6	0.3	-0.3	-0.2	0.6
Pulse wave peak to peak time	0.1	0.1	0.6	-0.2	-0.0	-0.8	-0.1	0.4	-0.1	0.3	-0.3	-0.1
Medication for pain relief, constipation, heartburn	0.1	0.2	0.5	0.5	-0.6	-0.0	0.1	0.7	0.3	0.6	-0.6	0.2
Medication: Seretide 50 evohaler	0.1	0.1	0.3	0.1	0.2	-0.4	0.3	0.1	-0.2	0.1	-0.3	-0.5
Hypertension (Self-reported)	0.1	0.2	0.4	-0.2	0.5	0.6	-0.7	0.3	-0.1	-0.2	0.0	0.5
Leg fat percentage (left)	0.1	0.4	1.5	0.5	0.4	1.2	-1.2	0.7	-0.2	-0.5	-0.3	0.4
Vascular/heart problems diagnosed by doctor	0.1	0.4	1.4	0.1	-0.9	-0.1	1.2	-0.6	0.7	0.6	0.2	-0.4
Heart disease (siblings)	0.1	0.1	0.5	-0.1	-0.2	0.7	-0.1	0.3	0.1	0.5	-0.2	0.2

Hub : Genes

LRRC58

Models

Trait associations