TWAS hub - MAGEF1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2270	0.0520	3.3e-06	0.091	NA	0.085	NA	0.100	6.5e-08	NA	1.8e-07	NA	1.6e-08
2	GTEx	Artery Tibial	0.1534	0.0489	1.1e-03	0.095	NA	0.072	NA	0.085	6.8e-08	NA	2.7e-06	NA	3.7e-07
3	GTEx	Breast Mammary Tissue	0.3790	0.0950	9.0e-05	0.038	NA	0.048	NA	0.037	4.8e-03	NA	1.7e-03	NA	5.6e-03
4	GTEx	Breast Mammary Tissue (Female)	0.1152	0.0934	1.8e-01	0.115	NA	-0.008	NA	0.071	2.6e-04	NA	6.8e-01	NA	3.8e-03
5	GTEx	Cells Transformed fibroblasts	0.1920	0.0640	5.7e-04	0.073	NA	0.113	NA	0.140	3.8e-06	NA	8.3e-09	NA	1.1e-10
6	GTEx	Esophagus Mucosa	0.1440	0.0450	4.9e-04	0.097	NA	0.093	NA	0.106	5.1e-07	NA	9.4e-07	NA	1.5e-07
7	GTEx	Esophagus Muscularis	0.2280	0.0550	1.3e-05	0.143	NA	0.098	NA	0.145	5.5e-09	NA	1.5e-06	NA	4.2e-09
8	GTEx	Lung	0.1394	0.0412	3.1e-04	0.069	NA	0.072	NA	0.074	5.3e-06	NA	3.3e-06	NA	2.7e-06
9	GTEx	Nerve Tibial	0.1763	0.0675	4.2e-03	0.013	NA	0.036	NA	0.031	3.5e-02	NA	1.3e-03	NA	2.7e-03
10	GTEx	Skin Sun Exposed Lower leg	0.2250	0.0490	3.5e-07	0.152	NA	0.096	NA	0.126	1.4e-12	NA	2.5e-08	NA	1.4e-10
11	METSIM	Adipose	0.1156	0.0335	2.0e-05	0.039	0.024	0.032	0.034	0.023	1.6e-06	0.00014	1.2e-05	7.2e-06	1.6e-04
12	NTR	Blood	0.0183	0.0086	1.8e-02	0.003	0.005	0.002	0.006	0.002	3.8e-02	0.00650	8.1e-02	2.9e-03	6.8e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Medication: Seretide 50 evohaler	5.5	6.3	10.1	2.6	3.2	0.2	2.6	2.4	1.9	3.1	2.6	2.8	2.7	2.2	2.5
Vitamin and mineral supplements	5.1	6.9	9.1	2.6	2.7	2.5	2.7	2.6	2.5	2.6	3.0	3.0	2.5	1.8	2.7
Breast Cancer	4.6	11.0	15.0	-3.4	-3.2	-2.4	-3.1	-3.9	-3.7	-3.3	-3.5	-3.8	-3.5	-2.2	-3.5
Medication: Ibuprofen	4.5	5.4	8.7	-2.6	-2.0	-0.8	-1.9	-2.7	-2.7	-2.3	-2.7	-3.0	-2.6	-2.0	-1.8
Medication: Ibuprofen (e.g. Nurofen)	4.4	5.6	8.3	-2.6	-2.0	-0.8	-2.0	-2.8	-2.8	-2.3	-2.7	-2.8	-2.9	-2.1	-1.8
Multivitamins +/- minerals	4.3	5.4	11.0	-2.2	-2.2	-2.4	-2.1	-2.4	-2.4	-2.2	-2.4	-3.3	-2.2	-1.7	-2.1
Headache pain in last month	4.0	6.9	10.6	-2.8	-2.3	-1.8	-2.4	-2.5	-3.0	-2.3	-3.0	-3.0	-2.4	-2.4	-3.3
Deep venous thrombosis (DVT) (self-reported)	3.8	4.9	8.9	2.3	2.5	-0.3	2.3	2.0	1.8	2.5	1.8	2.6	2.2	2.1	3.0
Blood clot in the leg (DVT)	3.6	4.7	8.5	2.2	2.4	-0.3	2.2	2.1	1.9	2.5	1.7	2.4	2.2	2.0	2.9
Noisy workplace	3.5	4.3	6.3	-1.9	-2.0	-2.5	-2.2	-1.8	-2.2	-2.2	-2.1	-1.9	-2.1	-2.1	-1.5
Irritable Bowel Disease (IBD)	3.2	7.7	12.0	2.6	3.3	1.2	3.2	3.0	2.3	3.0	3.2	2.0	2.6	3.5	2.5
Eye problems/disorders: Cataract	3.1	3.6	6.2	-2.1	-2.5	-0.5	-2.1	-2.0	-1.6	-2.3	-2.5	-1.3	-2.0	-1.4	-1.4
Diabetes (self-reported)	3.0	4.7	7.8	2.5	2.1	1.4	2.1	2.2	2.8	2.2	1.8	2.3	2.7	1.5	2.0
Diabetes diagnosed by doctor	2.9	4.7	8.1	2.4	2.0	1.4	1.9	2.3	2.8	2.1	2.0	2.2	2.8	1.6	2.1
Leg fat mass (right)	2.7	10.5	18.8	3.7	3.5	3.9	3.3	4.3	3.2	3.4	2.2	3.1	3.5	1.8	2.0
Arm fat percentage (right)	2.6	10.4	17.8	3.7	3.3	4.2	3.3	4.1	3.3	3.1	1.7	3.3	3.0	1.8	2.9
Bilateral oophorectomy (both ovaries removed)	2.5	2.8	6.9	1.8	1.3	1.6	1.5	1.5	2.6	1.7	1.9	1.1	1.8	2.0	0.5
Whole body fat mass	2.5	10.3	17.8	3.6	3.3	4.2	3.3	4.2	3.3	3.2	2.0	3.3	3.2	1.8	2.1
Pain type(s) experienced in last month: Hip pain	2.5	3.1	5.2	-1.7	-1.7	-1.0	-1.4	-0.9	-1.7	-2.0	-2.1	-2.2	-1.9	-1.6	-2.3
Leg fat mass (left)	2.5	9.7	16.6	3.5	3.3	3.8	3.1	4.1	3.2	3.3	2.0	3.1	3.4	1.8	2.1
Ulcerative Colitis (UC)	2.4	4.4	8.5	1.8	2.7	0.5	2.6	2.3	1.5	2.3	2.1	1.2	2.0	2.9	2.0
Average weekly fortified wine intake	2.4	2.8	8.6	-1.8	-1.6	-1.5	-1.6	-0.5	-2.0	-1.4	-1.6	-2.9	-1.2	-0.6	-1.9
Medication: Simvastatin	2.4	3.5	5.3	2.2	2.3	2.1	2.3	1.9	1.2	2.2	1.8	1.5	2.0	0.8	1.7
Arm fat mass (right)	2.4	10.0	17.1	3.6	3.3	4.1	3.2	4.1	3.2	3.2	2.0	3.0	3.2	1.6	2.2
Birth weight	2.4	5.3	11.8	-2.4	-1.8	-0.1	-1.7	-2.7	-2.4	-2.0	-2.5	-2.8	-2.3	-1.9	-3.4
Depression (Nagel 2018)	2.2	3.3	6.7	-1.8	-1.8	-1.8	-1.8	-2.6	-1.4	-1.7	-2.3	-1.3	-1.8	-1.8	-1.2
Age at first live birth	2.2	4.0	9.2	-2.2	-1.7	-2.2	-1.5	-3.0	-2.6	-1.9	-1.6	-1.9	-2.1	-0.7	-1.4
Arm fat mass (left)	2.2	8.9	17.1	3.4	3.0	4.1	3.0	3.9	3.1	3.0	1.9	2.8	3.1	1.3	2.1
Supplements: Zinc	2.1	2.3	4.1	-1.5	-1.8	-1.1	-2.0	-1.1	-1.3	-1.7	-1.7	-1.5	-1.5	-1.3	-1.3
Trunk fat mass	2.1	9.0	15.7	3.3	3.1	3.9	3.1	4.0	3.0	3.0	1.8	3.2	3.1	1.5	2.0
Hair/balding pattern: Pattern 2	2.1	2.7	4.5	-1.6	-1.9	-1.2	-1.6	-1.4	-1.5	-1.9	-1.4	-1.4	-2.1	-2.0	-1.4
Arm fat percentage (left)	2.1	8.3	14.5	3.3	2.9	3.8	2.9	3.8	2.9	2.8	1.4	2.8	2.8	1.6	2.6
Mineral and other dietary supplements	2.1	2.8	5.5	1.2	1.4	0.7	1.5	2.4	2.3	1.6	1.5	1.9	2.2	1.0	1.6
Depressed Affect (Nagel 2018)	2.0	4.2	7.5	-1.8	-1.8	-2.4	-1.5	-2.4	-2.1	-2.0	-2.7	-1.7	-2.1	-2.3	-1.5
Crohns Disease (2017)	2.0	4.5	8.4	2.0	2.4	1.2	2.3	2.9	1.7	2.2	2.6	1.7	2.2	2.0	1.6
Type 2 Diabetes (T2D) (2018)	2.0	3.7	5.6	2.3	2.2	0.7	2.0	2.0	2.1	2.1	1.6	1.9	2.4	1.1	1.8
Stomach or abdominal pain in last month	2.0	2.5	3.5	-1.6	-1.9	-0.8	-1.7	-1.5	-1.4	-1.8	-1.8	-1.8	-1.5	-1.7	-1.2
Prospective memory result	2.0	2.4	6.0	-1.7	-1.7	-0.3	-1.9	-0.8	-0.8	-1.5	-2.5	-1.6	-1.4	-1.4	-1.9
Number of children fathered	2.0	2.3	3.1	-1.7	-1.6	-0.1	-1.7	-1.1	-1.6	-1.6	-1.8	-1.4	-1.6	-1.7	-1.4
Supplements: Fish oil (including cod liver oil)	2.0	2.6	4.5	-1.2	-1.3	-1.5	-1.3	-2.1	-2.1	-1.4	-1.5	-2.0	-2.1	-0.8	-1.4
Medication: Metformin	1.9	2.7	5.0	2.0	1.6	0.4	1.5	2.2	2.1	1.6	1.3	1.9	1.9	0.8	1.3
Body fat percentage	1.9	7.5	14.2	3.1	2.6	3.7	2.7	3.8	2.8	2.6	1.2	3.0	2.7	1.5	2.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.3	4.1	1.4	1.4	1.4	1.2	1.1	1.3	1.3	2.0	1.9	1.3	1.8	1.8
Medication: Omeprazole (e.g. Zanprol)	1.9	2.4	7.2	-1.1	-1.7	-1.2	-1.7	-0.8	-1.0	-1.6	-1.7	-1.5	-1.5	-2.7	-0.7
Schizophrenia vs Biploar Disorder	1.8	2.4	5.2	1.5	1.4	0.1	1.2	2.0	1.6	1.5	1.3	1.3	2.0	2.3	1.2
Ulcerative Colitis	1.8	2.6	5.7	1.4	2.1	0.4	2.0	0.7	1.2	1.9	1.9	0.6	1.4	2.4	1.9
Gout (self-reported)	1.8	2.5	3.8	1.6	1.6	1.6	1.5	1.3	1.4	1.6	2.0	1.7	1.7	1.4	1.2
Medication for pain relief, constipation, heartburn	1.8	3.0	8.8	1.7	1.7	1.1	2.3	1.5	1.5	1.5	1.3	1.9	1.5	3.0	1.2
Lupus	1.7	2.5	7.6	1.6	1.7	2.8	1.8	1.1	1.1	1.6	1.9	0.6	1.1	0.4	1.8
Trunk fat percentage	1.7	6.8	12.6	2.9	2.4	3.5	2.5	3.5	2.8	2.4	1.1	3.0	2.6	1.3	2.1
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	4.4	-0.9	-2.1	-0.6	-2.0	-2.0	-0.6	-2.0	-1.6	-0.1	-1.8	-0.3	0.4
Body mass index (BMI)	1.7	7.1	13.1	3.1	2.9	3.1	2.8	3.6	2.6	2.9	1.7	2.2	3.0	1.2	1.8
Leg fat percentage (right)	1.7	6.0	14.1	2.8	2.5	3.2	2.4	3.8	2.2	2.4	1.1	2.4	2.6	1.2	1.5
Mood swings	1.7	3.0	8.2	-1.3	-1.3	-1.4	-1.2	-1.5	-1.6	-1.7	-2.9	-1.9	-2.1	-2.0	-0.9
Hearing aid user	1.7	1.9	3.3	-1.3	-1.5	-0.7	-1.0	-1.7	-1.8	-1.7	-1.6	-0.4	-1.8	-1.6	-0.5
Basal cell carcinoma (self-reported)	1.7	2.0	5.2	-1.4	-1.3	-1.3	-1.2	0.1	-1.3	-1.2	-1.9	-2.3	-1.0	-1.5	-1.5
Cardiovascular Disease	1.6	5.4	11.6	2.5	2.3	0.2	2.2	2.8	1.8	2.4	2.1	3.4	2.4	0.3	3.3
Frequency of depressed mood in last 2 weeks	1.6	2.2	4.8	-1.5	-1.6	-1.2	-1.4	-2.0	-0.9	-1.5	-2.2	-1.2	-1.5	-1.8	-0.3
Fed-up feelings	1.6	2.9	14.3	-1.3	-1.3	-3.8	-1.4	-1.3	-0.8	-1.3	-2.3	-1.1	-1.4	-1.7	0.1
Medication: Aspirin	1.6	2.1	4.5	1.6	1.5	1.1	0.7	1.8	1.5	1.7	2.1	1.2	1.8	-0.5	0.8
Medication: Aspirin	1.6	2.1	3.6	1.7	1.6	1.1	0.8	1.6	1.6	1.6	1.9	1.5	1.5	-0.6	1.3
Leg fat percentage (left)	1.6	5.9	13.0	2.7	2.4	3.1	2.2	3.6	2.4	2.3	1.1	2.5	2.6	1.4	1.8
Hair/balding pattern: Pattern 4	1.5	3.6	7.9	2.6	1.3	1.3	1.1	1.5	2.8	1.4	1.2	2.0	2.0	2.2	2.4
Risk taking	1.5	2.1	5.4	1.3	1.3	0.2	0.9	2.3	1.8	1.5	2.3	1.2	1.6	0.7	0.6
Mean Putamen Volume	1.4	1.6	2.8	1.2	1.7	1.6	1.6	1.3	0.5	1.4	1.3	1.2	1.6	0.7	0.2
Falls in the last year	1.4	1.9	4.2	-1.3	-1.3	-0.2	-1.0	-0.3	-1.5	-1.3	-1.7	-2.0	-1.6	-0.8	-2.1
Depression (self-reported)	1.4	1.7	4.0	-1.6	-1.5	-1.6	-1.3	-2.0	-1.0	-1.3	-1.3	-1.1	-1.1	-0.2	-0.5
Exposure to tobacco smoke at home	1.4	1.5	3.5	-1.1	-1.2	-0.4	-0.9	-1.7	-1.1	-1.1	-1.4	-1.5	-1.1	-1.9	-0.8
Medication for cholesterol, blood pressure or diabetes	1.4	2.4	4.6	-1.6	-1.8	-0.3	-1.5	-1.2	-1.2	-1.7	-1.7	-2.0	-1.7	-0.0	-2.1
Leg pain on walking	1.4	1.7	3.3	-1.0	-1.3	0.4	-1.3	-1.7	-1.1	-1.4	-1.8	-0.7	-1.5	-1.6	-1.2
Medication: Bendroflumethiazide	1.4	2.1	3.3	1.4	1.7	0.4	1.5	1.4	1.6	1.7	1.8	1.7	1.8	0.6	1.0
Crohns Disease (2012)	1.3	2.1	4.6	0.8	1.2	1.7	1.4	2.1	1.0	1.2	2.0	1.0	1.4	1.5	1.3
Ever used hormone-replacement therapy (HRT)	1.3	1.6	4.5	-1.0	-2.0	-0.1	-2.1	-0.5	-0.1	-1.3	-1.1	-1.2	-0.5	-1.9	-1.2
Weight	1.3	6.6	14.7	2.8	2.8	3.8	2.7	3.2	2.4	2.7	1.9	2.4	2.7	0.9	1.1
Illnesses of mother	1.3	1.6	4.7	1.2	1.3	1.1	1.6	1.0	0.6	1.2	1.1	0.6	0.9	2.2	1.7
Health satisfaction	1.3	1.7	4.0	-1.0	-1.2	-0.7	-1.4	-1.1	-0.8	-1.1	-1.7	-1.7	-1.1	-0.9	-2.0
Medication: Blood pressure	1.3	2.3	4.0	1.4	1.8	-0.3	1.5	2.0	1.3	1.8	1.7	1.6	1.7	0.1	1.6
Average weekly beer plus cider intake	1.3	1.9	4.3	1.9	1.1	1.1	1.1	0.8	2.0	1.1	1.5	1.4	1.0	-0.1	2.1
Neuroticism (Nagel 2018)	1.2	2.8	8.1	-1.3	-1.5	-2.8	-1.4	-1.9	-1.2	-1.4	-2.3	-1.4	-1.3	-1.8	-0.4
BMI	1.2	7.0	10.7	3.2	2.9	3.1	2.6	3.3	2.6	2.9	2.0	2.6	2.8	0.9	2.0
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	3.5	-1.2	-1.7	-1.2	-1.6	-1.9	-0.4	-1.4	-1.8	-1.7	-1.3	-0.9	-0.9
Had menopause	1.2	1.5	4.1	1.6	0.5	1.9	0.4	1.2	2.0	0.7	0.8	1.5	1.3	0.5	0.9
Age at last live birth	1.2	1.7	6.3	-1.5	-0.9	-1.5	-0.7	-2.5	-1.8	-1.1	-0.6	-0.9	-1.4	-0.6	-0.9
Average weekly red wine intake	1.2	1.8	4.8	-1.6	-1.5	-0.4	-1.3	-0.9	-1.2	-1.6	-0.7	-0.8	-1.4	-1.7	-2.2
Commuting to job workplace: Cycle	1.2	1.5	3.7	-1.6	-1.6	-0.7	-1.6	-0.6	-1.3	-1.3	-0.7	-0.9	-0.8	-0.5	-1.9
Age at First Birth	1.1	1.6	3.9	-1.0	-1.1	-0.7	-1.2	-2.0	-1.4	-1.5	-1.2	-0.5	-1.9	-1.2	-0.4
HbA1C	1.1	1.2	2.1	-1.1	-1.0	-0.2	-1.0	-1.0	-1.3	-1.3	-1.3	-1.0	-1.5	-1.2	-0.3
Diabetes (mother)	1.1	1.4	4.4	-0.6	-0.6	0.6	-0.5	-1.5	-0.7	-0.9	-1.6	-0.4	-1.1	-2.1	-1.7
Pack years adult smoking proportion	1.1	1.7	3.0	1.5	1.7	-0.3	1.3	1.1	1.7	1.6	1.1	0.8	1.2	1.2	1.4
Leg fat-free mass (left)	1.1	6.1	11.7	2.5	2.8	3.4	2.7	2.9	2.2	2.8	2.4	2.0	2.6	0.8	1.0
Leg predicted mass (left)	1.1	6.1	11.3	2.5	2.8	3.4	2.7	2.9	2.2	2.8	2.4	2.1	2.6	0.8	1.0
Leg fat-free mass (right)	1.1	5.7	10.2	2.4	2.7	3.2	2.6	2.6	2.2	2.7	2.4	2.1	2.6	0.9	1.1
Smoking status: Current	1.1	1.7	5.6	-1.2	-1.2	-0.5	-1.3	-2.4	-0.1	-1.1	-1.4	-0.8	-1.0	-1.3	-1.8
Basal metabolic rate	1.1	5.9	11.4	2.5	2.8	3.4	2.6	2.9	2.1	2.7	2.4	2.0	2.6	0.7	0.7
Arm fat-free mass (left)	1.1	5.6	10.0	2.4	2.8	3.2	2.6	2.9	1.9	2.7	2.4	1.8	2.7	0.7	0.3
Alcohol drinker status: Previous	1.1	1.3	2.3	-1.1	-1.4	-0.9	-1.4	-1.1	-0.9	-1.5	-1.3	-1.0	-1.2	-0.7	-0.6
Alzheimer’s Disease (in mother)	1.0	1.1	2.3	0.9	1.1	1.0	1.2	1.4	1.2	1.1	0.9	0.1	1.1	1.5	0.2
Smoking Status	1.0	2.5	4.5	-1.8	-1.9	-0.9	-1.9	-2.1	-1.3	-1.9	-1.0	-1.2	-1.6	-1.7	-1.0
Medication: Cholesterol lowering	1.0	1.6	2.5	1.4	1.4	1.3	1.6	0.7	0.9	1.3	1.5	1.3	1.0	-0.1	1.6
Tense / ‘highly strung’	1.0	1.6	3.2	-1.4	-1.8	-1.1	-1.7	-1.1	-0.2	-1.3	-1.4	-0.9	-1.0	-1.6	-0.6
Medication: Ventolin 100micrograms inhaler	1.0	1.2	2.3	1.0	1.3	0.6	1.2	1.4	1.1	1.2	1.1	1.4	1.5	0.5	-0.2
Heart disease (mother)	1.0	1.3	2.9	1.0	1.2	-0.1	0.5	1.2	1.2	1.3	1.5	1.7	1.2	-0.0	1.1
Qualifications: nursing, teaching	1.0	1.5	4.7	-1.3	-1.0	-2.2	-1.2	-0.3	-0.9	-0.8	-0.5	-1.7	-0.5	-1.5	-1.5
Leg predicted mass (right)	1.0	5.3	9.4	2.3	2.6	3.1	2.5	2.5	2.1	2.6	2.4	2.0	2.5	0.9	1.0
Average weekly champagne plus white wine intake	1.0	1.4	4.2	0.9	1.4	0.4	1.2	0.7	0.8	1.3	2.1	1.3	1.6	0.6	-0.6
Unable to work because of sickness or disability	1.0	1.2	3.1	-1.3	-1.1	-1.8	-1.3	-1.2	-0.5	-1.2	-1.2	-1.1	-0.7	-0.9	0.0
Arm predicted mass (left)	1.0	5.3	8.6	2.4	2.7	2.9	2.5	2.9	1.9	2.6	2.4	1.8	2.6	0.7	0.5
Blood Platelet Count	0.9	10.0	65.8	-1.8	-1.3	2.6	-1.2	-0.9	-3.0	-1.5	8.1	1.1	-1.8	-3.1	-3.8
Maternal smoking around birth	0.9	1.3	4.2	1.0	0.5	0.8	0.5	1.6	1.6	0.7	1.2	2.0	1.3	0.5	0.5
High blood pressure	0.9	2.5	5.3	1.6	1.5	-0.2	1.1	2.3	1.5	1.7	1.3	2.2	1.8	-0.6	1.8
Illnesses of siblings	0.9	1.3	4.9	0.7	1.0	1.3	1.4	1.1	0.8	0.9	1.1	0.7	0.8	2.2	0.2
Hip circumference	0.9	4.0	11.1	2.1	2.2	3.3	2.2	2.8	1.8	2.0	1.0	1.6	1.8	0.5	0.0
Pulse wave Arterial Stiffness index	0.9	1.1	2.5	-1.1	-1.1	0.4	-0.9	-1.6	-0.8	-1.3	-0.6	-0.3	-1.4	-1.6	-0.1
Pulse wave peak to peak time	0.9	1.1	2.7	1.1	1.2	-0.0	1.0	1.5	0.7	1.3	0.6	0.3	1.3	1.6	0.0
Shortness of breath walking on level ground	0.9	1.1	2.5	0.7	0.7	1.5	0.6	1.0	1.2	1.0	0.8	1.6	1.3	0.5	1.0
Mouth/teeth dental problems: Loose teeth	0.9	1.0	2.3	-0.8	-1.4	-0.8	-1.4	-0.5	-0.5	-1.5	-1.2	-0.8	-1.1	-1.1	0.1
Medication: Omeprazole	0.9	1.1	3.7	-0.4	-0.9	-0.9	-1.1	-0.7	-0.5	-1.0	-1.3	-1.1	-1.1	-1.9	-0.2
Family relationship satisfaction	0.9	1.1	2.8	-0.5	-1.1	-1.4	-1.5	-1.0	-0.3	-1.1	-0.4	-0.8	-1.1	-1.7	-0.8
Guilty feelings	0.9	1.4	4.0	-1.1	-0.9	-1.7	-0.6	-0.9	-1.2	-0.9	-2.0	-1.7	-0.8	-0.6	0.3
Ovarian Cancer	0.8	1.1	2.7	-1.0	-0.8	-0.9	-0.5	-0.9	-1.7	-1.1	-1.4	-0.7	-1.2	-0.5	-1.3
Allergy or Eczema	0.8	2.2	3.6	-1.7	-1.5	-0.9	-1.2	-1.8	-1.9	-1.6	-0.9	-1.1	-1.5	-1.4	-1.6
Severe depression (siblings)	0.8	0.9	1.6	-1.3	-1.1	-0.7	-1.1	-0.2	-1.2	-1.0	-0.7	-0.9	-0.8	-0.5	-1.2
Waist circumference	0.8	2.8	5.9	1.9	1.5	2.2	1.3	2.4	2.0	1.6	0.7	1.9	1.9	0.3	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	4.8	-1.0	-0.8	-1.4	-0.7	-1.2	-0.8	-0.9	-1.2	-0.5	-1.4	-2.2	0.4
Forced vital capacity (FVC), Best measure	0.8	2.8	5.2	-1.7	-1.1	-0.3	-1.1	-2.0	-2.1	-1.4	-1.2	-2.1	-1.6	-1.8	-2.3
Arm predicted mass (right)	0.8	4.3	6.7	2.1	2.4	2.3	2.2	2.6	1.7	2.4	2.5	1.4	2.5	0.8	0.4
Hypertension (Self-reported)	0.8	2.3	4.7	1.6	1.6	-0.2	1.2	2.0	1.3	1.6	1.3	2.2	1.7	-0.4	1.8
Illnesses of father: Heart disease	0.8	1.1	4.8	0.8	1.2	2.2	0.7	1.0	0.4	1.2	1.3	0.5	1.2	0.6	0.4
Whole body fat-free mass	0.8	4.3	9.0	2.0	2.5	3.0	2.3	2.4	1.6	2.4	2.4	1.5	2.3	0.4	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	5.1	-1.2	-0.8	-0.2	-0.8	-0.4	-1.6	-1.0	-1.6	-2.2	-1.2	-1.3	-1.5
Whole body water mass	0.8	4.4	8.5	2.1	2.5	2.9	2.4	2.5	1.6	2.4	2.4	1.5	2.3	0.5	0.3
Financial situation satisfaction	0.8	1.0	5.4	-0.3	-1.0	-0.0	-1.0	-2.3	-0.0	-0.9	-1.3	-0.2	-1.0	-0.9	-0.0
Myopia	0.8	1.2	3.0	-1.0	-1.1	-0.9	-1.2	-1.1	-0.8	-1.1	-1.3	0.6	-1.2	-1.7	0.3
Major Depression (MDD)	0.7	0.9	6.3	-0.5	-0.3	-0.9	-0.1	-0.2	-0.6	-0.5	-0.3	-0.9	-1.1	-2.5	-0.8
Prostate Cancer	0.7	1.0	3.6	-0.3	-1.0	-1.9	-1.1	-1.5	-0.2	-1.0	-1.0	-1.4	-0.7	0.3	-0.1
Triglycerides	0.7	1.2	3.0	0.7	1.3	-0.5	1.7	1.1	0.3	1.1	1.5	0.7	0.9	1.7	0.2
Lung FVC	0.7	3.3	9.2	-2.1	-1.2	-2.1	-1.4	-0.8	-2.5	-1.2	-1.7	-3.0	-1.0	-0.7	-2.4
Age when periods started (menarche)	0.7	1.7	3.9	-1.7	-1.5	-1.2	-1.3	-2.0	-1.6	-1.4	-0.4	-0.6	-1.4	-0.7	0.8
Medication: Levothyroxine sodium	0.7	1.3	3.7	-0.9	-0.4	1.4	-0.6	-0.6	-1.9	-0.6	-1.7	-1.3	-0.9	-0.8	-1.3
Alcohol usually taken with meals	0.7	1.1	3.3	-1.6	-0.8	0.6	-0.5	-1.0	-1.3	-0.9	-0.7	-0.1	-0.8	-0.9	-1.8
Had other major operations	0.7	0.8	2.4	0.6	0.7	-0.7	0.4	1.5	0.7	1.0	0.9	0.6	1.5	0.9	-0.3
Financial difficulties in last 2 years	0.7	0.9	4.1	-0.4	-1.0	0.1	-0.8	-1.0	0.1	-0.8	-1.2	-1.0	-0.4	-2.0	-0.9
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	3.3	-1.4	-1.2	0.2	-0.7	-1.8	-0.8	-1.1	-1.0	-0.7	-1.1	-0.5	-0.3
Lung cancer (father)	0.7	0.8	2.9	0.7	0.8	0.3	0.6	1.7	1.3	1.0	0.6	0.4	1.4	0.4	-0.5
Breastfed as a baby	0.7	0.9	1.8	-0.9	-1.1	-0.6	-1.0	-1.0	-1.0	-1.1	-0.7	-0.6	-1.3	-0.5	-1.1
Ever highly irritable/argumentative for 2 days	0.7	0.8	1.6	-0.7	-1.0	0.4	-0.9	-1.1	-0.3	-1.0	-1.1	-0.9	-1.1	-1.2	-0.5
Arm fat-free mass (right)	0.7	3.8	6.0	1.9	2.4	2.3	2.2	2.3	1.4	2.4	2.5	1.2	2.4	0.7	0.3
Medication: Allopurinol	0.7	0.9	2.2	0.4	0.5	1.5	0.3	1.1	1.2	0.7	1.4	1.0	1.1	0.6	0.4
Loneliness, isolation	0.7	0.9	3.5	-0.5	-0.8	-0.6	-0.6	-1.9	-0.3	-0.8	-1.7	-1.1	-1.1	-0.4	-0.4
Osteoarthritis (self-reported)	0.7	0.9	1.8	1.1	1.2	0.6	1.0	0.7	0.9	1.0	0.5	0.9	0.8	1.0	1.4
Diastolic blood pressure, automated reading	0.7	2.3	3.7	1.5	1.9	1.6	1.6	1.1	1.1	1.9	1.1	1.6	1.9	-0.3	1.6
Pack years of smoking	0.7	1.1	1.7	1.1	1.3	-0.8	0.9	0.9	1.3	1.2	0.9	0.5	0.9	1.2	0.9
Intelligence (Savage-Jansen 2018)	0.6	2.0	3.6	-1.6	-1.5	-0.7	-1.5	-1.9	-1.3	-1.9	-0.1	-1.1	-1.9	-0.7	-1.5
Reaction Time	0.6	1.1	4.3	0.8	0.8	2.1	0.7	0.8	0.7	1.3	0.2	0.3	1.2	1.6	0.7
Rheumatoid Arthritis	0.6	0.9	1.6	1.0	1.0	1.2	0.9	0.6	0.8	0.9	1.0	0.4	0.6	1.2	1.3
Neuroticism	0.6	1.5	4.7	-1.1	-1.3	-2.2	-1.2	-1.0	-0.7	-1.0	-1.8	-0.9	-0.8	-1.4	0.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.7	1.8	-1.1	-1.3	-0.1	-1.3	-0.8	-0.9	-1.0	-0.7	-0.3	-0.5	-0.7	-0.6
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.5	0.6	0.6	0.0	0.4	1.6	1.5	0.8	0.6	0.2	1.2	-0.3	0.1
Townsend deprivation index at recruitment	0.6	0.8	2.9	-1.1	-1.2	-0.5	-1.0	-1.0	-0.2	-0.9	-0.4	-1.1	-0.3	-1.7	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	5.8	-1.4	-0.2	-0.5	-0.3	-0.9	-2.1	-0.5	-0.9	-1.2	-0.3	-1.0	-2.4
Neuroticism score	0.6	1.2	3.5	-0.8	-1.0	-1.5	-0.8	-1.2	-0.2	-1.0	-1.9	-1.2	-0.9	-1.1	0.7
Number of live births	0.6	0.8	1.4	1.2	1.1	0.6	1.1	1.2	0.8	1.0	0.7	0.7	1.0	0.8	-0.3
Pulse rate	0.6	1.0	2.6	-0.9	-0.9	-1.2	-1.0	-1.6	-0.8	-1.0	-1.1	0.0	-0.9	-1.4	0.1
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	3.3	-0.9	-0.8	-0.3	-0.7	-1.3	-0.8	-0.8	-0.1	-1.1	-0.9	-1.8	-1.0
Medication: Amlodipine	0.6	0.9	2.7	0.6	0.7	-0.4	0.9	1.1	1.2	0.6	0.6	1.6	0.6	0.4	1.5
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.9	-0.8	-1.3	-0.3	-1.4	-0.5	-0.6	-0.9	-0.7	-0.5	-0.8	-0.7	-0.7
Emphysema/chronic bronchitis	0.6	0.6	2.2	-0.6	-1.2	-1.1	-1.5	0.3	0.1	-1.0	-1.0	-0.2	-0.5	-0.5	-0.1
Migraine (self-reported)	0.6	0.8	4.6	-0.9	-0.1	-2.1	-0.5	0.1	-0.7	-0.1	-0.6	-0.0	-0.3	-1.4	-0.8
Suffer from ‘nerves’	0.6	1.0	2.2	-0.7	-1.1	-1.3	-1.2	-0.7	-0.2	-0.9	-1.5	-1.2	-1.0	-0.9	-0.5
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.7	-1.0	-0.6	-1.3	-0.7	-0.4	-0.9	-0.7	-1.2	-0.5	-0.8	-0.2	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	3.5	-1.2	-1.4	0.1	-1.6	-1.9	-0.6	-1.2	-0.1	0.3	-1.1	-1.9	0.0
Commuting to job workplace: Walk	0.6	0.7	2.0	0.7	0.7	1.4	0.6	-0.2	1.0	0.7	0.7	0.8	0.9	0.3	1.2
Asthma (self-reported)	0.6	1.2	2.5	1.1	1.5	0.4	1.4	1.2	1.0	1.3	1.1	0.8	1.6	0.4	0.6
Miserableness	0.6	1.1	4.3	-0.7	-0.8	-1.0	-0.7	-1.2	-0.6	-1.0	-1.4	-0.7	-1.1	-2.1	0.0
Irritability	0.6	1.0	2.1	-0.6	-1.0	-1.2	-0.8	-1.4	-0.2	-1.1	-1.0	-0.9	-1.3	-1.2	0.9
Vascular/heart problems diagnosed by doctor	0.6	1.6	4.0	-1.1	-1.0	0.1	-0.6	-2.0	-1.1	-1.3	-1.1	-1.8	-1.5	0.9	-1.4
Pain experienced in last month	0.6	1.0	4.5	1.1	0.7	0.6	0.9	-0.0	0.7	0.7	1.0	1.3	0.6	0.8	2.1
Alzheimer’s Disease (including proxy)	0.5	0.7	1.6	0.8	0.7	1.3	1.1	1.0	0.7	0.8	0.6	0.0	0.8	1.1	-0.0
Primary Biliary Cirrhosis	0.5	0.8	4.7	0.1	0.9	0.4	1.3	-0.1	0.0	0.7	0.7	0.6	0.4	2.2	0.4
Average weekly spirits intake	0.5	0.6	1.9	1.2	0.7	1.4	0.9	0.7	0.5	0.8	0.2	0.1	0.5	1.0	0.1
Ever had hysterectomy (womb removed)	0.5	0.6	2.8	0.9	0.2	-0.2	-0.1	0.9	1.7	0.6	0.6	-0.3	0.7	1.0	0.2
Current tobacco smoking	0.5	0.8	3.6	-0.7	-0.8	0.0	-0.9	-1.9	0.2	-0.7	-1.1	-0.2	-0.5	-1.0	-1.1
Sitting height	0.5	3.7	7.8	1.6	2.7	1.8	2.5	1.5	0.8	2.5	2.8	1.4	2.1	1.3	-0.0
Hearing difficulty/problems with background noise	0.5	0.9	2.0	-0.7	-1.4	-0.1	-1.3	-1.1	-0.2	-1.1	-0.7	-0.8	-0.2	-1.0	-1.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.4	-0.7	-0.7	-0.4	-0.7	-0.8	-0.4	-0.6	-0.7	-0.9	-0.8	-1.5	-0.2
Trunk fat-free mass	0.5	2.9	6.9	1.6	2.0	2.6	1.8	2.1	1.1	1.9	2.2	1.1	1.9	0.1	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	4.1	-1.2	-0.8	0.1	-0.8	-1.4	-1.5	-1.0	-0.9	-1.7	-1.1	-1.6	-2.0
Trunk predicted mass	0.5	3.1	7.1	1.6	2.1	2.7	1.9	2.1	1.1	2.0	2.2	1.0	1.9	0.1	-0.2
Medication: Paracetamol	0.5	0.9	2.1	-1.1	-1.0	-0.9	-1.4	-1.4	-0.1	-0.9	-0.8	-0.5	-0.6	-1.4	0.0
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.3	-0.9	-0.4	0.9	-0.6	-0.5	-1.5	-0.5	-1.4	-1.0	-0.8	-1.1	-1.0
Had major operations	0.5	0.6	3.2	-0.3	-0.2	-1.8	-0.7	-0.6	-0.4	0.0	0.2	-1.3	-0.0	0.0	-0.9
Knee pain experienced in last month	0.5	0.8	1.7	-1.0	-0.7	0.3	-0.5	-0.9	-0.9	-1.0	-0.7	-0.8	-1.0	-1.3	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.7	-0.4	-0.3	-0.6	-0.6	-0.9	-0.8	-0.5	-0.8	-0.7	-1.2	-1.3	0.1
Ever taken oral contraceptive pill	0.5	0.6	1.7	0.3	0.4	0.9	0.5	1.2	-0.3	0.3	1.2	0.2	0.4	0.8	1.3
Mother’s age at death	0.5	0.6	1.8	1.3	0.7	1.0	0.5	-0.6	0.9	0.5	0.8	0.2	0.1	0.2	1.2
Ever smoked	0.5	0.8	1.8	-0.8	-1.0	-0.1	-1.0	-1.2	-0.9	-1.2	-0.6	-0.4	-1.2	-1.3	-0.0
Number of operations (self-reported)	0.5	0.7	2.2	0.7	0.6	-0.9	0.3	1.1	0.8	0.9	1.2	0.3	1.5	0.5	-0.5
Worry (Nagel 2018)	0.4	0.9	2.3	-0.8	-1.2	-1.3	-1.0	-1.0	-0.3	-0.8	-1.5	-0.7	-0.5	-0.8	-0.1
Neuroticism (2016)	0.4	0.5	2.9	-0.1	-0.5	-1.3	-0.4	0.3	0.3	-0.4	-1.7	-0.7	-0.6	-0.5	0.0
Schizophrenia (2014)	0.4	0.9	4.6	0.3	0.5	0.5	0.5	2.1	1.1	0.8	1.1	0.6	0.9	1.2	0.5
Heel T-Score	0.4	2.8	7.7	-1.9	-0.5	-1.2	-0.4	-2.0	-2.8	-1.0	-1.1	-2.0	-1.4	-1.5	-2.3
Hypothyroidism (self reported)	0.4	0.9	2.8	-0.8	-0.4	-0.2	-0.7	-0.1	-1.2	-0.5	-1.7	-1.4	-0.8	-1.2	-1.1
Respiratory disease	0.4	0.8	3.2	-0.8	-0.6	-1.8	-0.9	-0.3	-0.7	-0.6	-0.8	-1.0	-0.2	-0.7	-1.2
Hearing difficulty/problems: Yes	0.4	0.6	3.2	-0.3	-0.7	-1.0	-0.7	-1.3	-0.4	-0.6	0.0	0.2	-0.3	-1.8	-0.5
Hand grip strength (right)	0.4	1.1	1.8	-1.0	-1.2	-1.1	-1.3	-1.0	-1.0	-1.3	-0.9	-1.4	-1.2	-0.7	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	2.9	-0.7	-0.9	-0.5	-0.8	-1.7	-0.1	-0.7	-0.8	-0.5	-0.4	-0.5	-0.1
Relative age voice broke	0.4	0.6	2.2	0.3	0.6	-1.5	0.6	0.7	-0.0	0.5	0.3	0.4	0.5	-0.5	1.5
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.9	-1.1	-0.6	-0.8	-0.2	-1.1	-1.4	-0.7	-0.3	0.1	-0.8	-1.1	-1.2
Chronic bronchitis/emphysema (father)	0.4	0.5	1.3	0.7	0.3	0.6	0.2	1.1	0.9	0.5	0.3	1.1	0.7	0.2	0.8
Qualifications: None of the above	0.4	0.9	3.0	0.9	0.7	0.0	0.5	1.7	0.7	0.9	0.2	0.5	0.9	1.1	1.4
Worrier / anxious feelings	0.4	0.7	2.5	-0.8	-1.0	-1.6	-0.9	-0.3	-0.1	-0.6	-1.5	-0.7	-0.1	-0.7	0.2
Happiness	0.4	0.5	2.9	0.1	-0.4	-0.0	-0.1	-1.7	0.1	-0.6	-0.8	-0.6	-0.9	-0.6	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.0	0.7	0.6	1.0	0.4	0.8	0.8	0.6	0.4	0.4	0.7	-0.6	0.5
Asthma	0.4	0.7	1.8	0.7	1.2	0.1	1.0	0.8	0.7	1.0	0.9	0.6	1.3	0.3	0.2
Pulse wave reflection index	0.4	0.5	1.8	0.6	0.5	1.1	0.5	-0.0	0.5	0.3	1.2	0.8	0.1	-0.5	1.3
Glaucoma (self-reported)	0.4	0.4	1.7	0.0	0.4	0.9	0.7	1.3	-0.0	0.3	0.9	0.5	0.5	0.1	0.6
Exposure to tobacco smoke outside home	0.4	0.5	1.4	0.6	0.8	0.3	0.9	1.2	0.8	0.8	0.2	0.1	0.2	1.0	0.5
Worry too long after embarrassment	0.4	0.7	3.1	-0.6	-0.8	-1.8	-0.6	-0.5	0.1	-0.7	-0.9	-0.7	-0.5	-0.7	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.3	0.7	0.7	0.1	0.7	1.0	-0.1	0.7	1.0	1.2	0.3	-0.6	0.1
Mean time to correctly identify matches	0.4	0.7	2.6	0.5	0.3	1.6	0.3	0.7	0.7	1.0	-0.1	0.5	1.0	1.4	0.5
Pulse rate, automated reading	0.4	1.2	3.0	-1.4	-0.8	-1.7	-1.3	-1.2	-1.2	-0.9	-0.7	-0.7	-0.7	-0.9	-1.0
Chest pain or discomfort	0.4	0.5	3.8	-0.0	-0.2	-2.0	-0.7	-0.2	0.4	-0.2	-0.6	-0.1	-0.3	-1.2	0.2
Illnesses of siblings: Diabetes	0.4	0.5	1.2	1.1	1.1	-0.2	1.0	0.0	0.8	0.8	0.4	0.7	0.3	0.5	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	2.4	-0.2	-0.3	-1.3	-0.7	-0.3	-0.4	-0.5	-0.2	-0.0	-0.4	-1.6	0.5
Osteoporosis (self-reported)	0.4	0.5	1.0	-0.9	-1.0	-0.3	-0.8	-0.5	-0.3	-0.9	-0.7	0.6	-1.0	-0.1	-0.3
Tinnitus: Yes, now most or all of the time	0.4	0.5	3.9	0.1	-0.3	-2.0	-0.4	0.8	0.4	-0.3	0.2	-0.5	0.2	0.3	0.3
Ever depressed for a whole week	0.4	0.5	1.2	0.7	0.7	0.8	0.7	0.6	1.0	0.8	0.6	0.7	0.4	-0.1	1.1
Impedance of whole body	0.4	1.9	3.8	-1.4	-1.9	-1.1	-1.6	-1.9	-0.6	-1.8	-1.8	-0.2	-1.7	-0.3	0.2
Coronary Artery Disease (CAD)	0.3	0.4	1.5	-0.1	0.2	-1.2	0.2	0.9	-0.7	0.0	0.1	-0.2	0.0	-1.2	-0.2
Type 2 Diabetes (T2D) (2012)	0.3	0.4	3.0	0.1	0.6	-1.7	0.5	0.4	-0.3	0.4	0.3	-0.3	0.1	-0.3	-0.0
Blood Eosinophil Count	0.3	2.2	6.1	-1.4	-1.6	0.3	-1.5	-1.1	-1.5	-1.5	-0.2	-0.9	-1.7	-2.5	-1.9
Hand grip strength (left)	0.3	0.8	3.4	-0.4	-0.8	-1.9	-0.9	-0.5	-0.5	-0.8	-0.6	-1.6	-0.7	-0.6	0.3
Relative age of first facial hair	0.3	0.5	2.4	0.6	0.5	-0.4	0.3	-0.1	0.6	0.4	0.9	1.6	0.2	0.7	1.2
Impedance of leg (right)	0.3	1.5	2.5	-1.2	-1.5	-1.1	-1.5	-1.4	-0.9	-1.6	-1.5	-0.4	-1.5	-0.6	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.5	-0.8	0.2	-0.1	0.1	-0.4	-1.5	-0.1	-0.4	-0.4	0.2	-1.0	-1.6
Medication: Atenolol	0.3	0.4	1.7	0.1	0.2	-0.7	0.5	1.3	-0.0	0.6	0.5	-0.1	1.0	0.4	0.3
High blood pressure (mother)	0.3	0.4	2.2	-0.3	-0.7	-0.6	-0.8	0.2	0.9	-0.4	-0.6	0.2	0.1	-1.5	0.0
Impedance of leg (left)	0.3	1.4	2.7	-1.2	-1.6	-1.1	-1.6	-1.6	-0.6	-1.6	-1.5	-0.1	-1.3	-0.2	-0.1
Heart attack	0.3	0.3	1.3	-0.7	-0.4	-0.0	-0.6	0.1	-0.2	-0.1	0.1	-0.9	0.1	-1.2	-0.9
Fluid intelligence score	0.3	0.6	1.5	-1.2	-0.8	-0.9	-0.6	-0.8	-0.9	-1.0	0.1	-0.7	-0.9	-0.4	-0.5
Time employed in main current job	0.3	0.3	1.0	-0.2	-0.9	-0.3	-0.7	-0.1	-0.3	-0.7	-0.2	0.6	-0.5	-1.0	0.7
High blood pressure (siblings)	0.3	0.4	3.0	-0.1	-0.5	-0.5	-0.9	-0.5	0.4	-0.1	-0.5	-0.1	0.2	-1.7	0.5
Comparative body size at age 10	0.3	0.8	5.7	-0.1	0.3	2.4	0.6	0.3	-0.3	-0.2	-0.0	-0.2	-0.6	-0.5	-1.5
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.5	-0.9	-0.6	-0.1	-0.3	-0.1	-0.7	-0.7	-0.0	-0.4	-0.4	0.7	-1.2
Long-standing illness, disability or infirmity	0.3	0.4	1.2	-0.7	-0.6	-0.4	-0.7	-0.6	-1.0	-0.8	-0.2	0.3	-0.5	-1.1	-0.1
Ever had bowel cancer screening	0.3	0.4	0.8	-0.7	-0.6	-0.6	-0.7	-0.1	-0.7	-0.8	-0.6	-0.7	-0.5	-0.9	-0.5
Friendships satisfaction	0.3	0.4	1.2	-0.2	-0.5	0.5	-0.5	-0.5	-0.3	-0.4	-0.3	-0.5	-0.7	-1.0	-1.1
Medication for cholesterol	0.3	0.5	2.1	-0.8	-0.7	-0.3	-0.6	-1.5	-0.3	-0.8	-0.7	-0.8	-0.7	-0.1	-0.3
Commuting to job workplace: Public transport	0.3	0.3	1.0	0.5	0.3	0.3	0.5	1.0	0.9	0.4	0.7	0.4	0.7	0.1	-0.1
Medication: Blood pressure	0.3	0.6	1.9	0.8	0.6	-0.0	0.5	1.4	0.6	0.8	0.4	0.9	1.2	-0.2	0.2
Medication: Lisinopril	0.3	0.4	1.8	0.1	0.1	-0.0	-0.3	1.4	0.6	0.8	0.4	0.1	1.2	-0.2	-0.0
Medication: Atorvastatin	0.3	0.4	2.4	0.2	-0.4	-1.5	-0.6	-0.2	0.0	-0.5	-0.3	-0.3	-0.7	-0.5	0.3
Age started oral contraceptive pill	0.3	0.3	1.1	-0.4	-0.9	0.4	-0.8	0.7	0.2	-0.4	-0.2	-0.5	0.3	1.0	-0.4
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.7	-0.7	-0.6	-0.3	-0.8	-0.2	-0.2	-0.3	-0.1	-0.9	-0.0	-1.3	-0.8
Heart disease (siblings)	0.3	0.3	1.7	0.4	0.8	-1.3	0.5	0.6	-0.6	0.5	-0.1	-0.3	-0.2	0.1	-0.5
Bipolar Disorder (2018)	0.2	0.4	1.9	-0.8	-0.2	0.5	-0.2	-0.3	-0.5	-0.1	0.2	0.0	-0.5	-1.0	-1.4
Body Mass Index (BMI) (2010)	0.2	0.3	0.8	-0.1	-0.1	0.9	-0.1	0.3	-0.1	-0.0	-0.5	-0.9	-0.1	-0.5	-0.9
Fasting Glucose	0.2	0.3	1.4	0.2	0.2	0.3	0.2	1.2	-0.2	0.4	0.2	0.6	0.6	-0.8	0.0
Waist Hip Ratio (WHR)	0.2	0.8	4.5	-0.0	-0.5	-2.1	-1.1	-0.6	0.7	-0.3	0.1	0.7	0.0	-0.5	1.6
Lung FEV1/FVC ratio	0.2	1.2	4.0	1.5	0.9	2.0	0.9	0.3	1.7	1.0	0.7	1.0	0.7	-0.0	0.9
Angina	0.2	0.3	1.0	-0.1	0.1	-0.9	-0.2	1.0	-0.1	0.0	-0.2	-0.5	0.1	-0.9	0.5
Diabetes (father)	0.2	0.3	0.8	-0.6	-0.3	-0.7	-0.6	-0.9	-0.5	-0.2	-0.2	0.1	-0.2	-0.8	-0.3
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.7	0.6	0.3	0.8	-0.1	0.3	0.1	0.3	0.3	0.3	0.2	-0.6	0.5
Qualifications: CSEs or equivalent	0.2	0.2	1.0	0.2	0.0	-0.2	-0.4	-0.4	0.0	0.2	-0.8	-0.6	-0.1	-1.0	0.4
Supplements: Glucosamine	0.2	0.3	0.9	0.2	0.1	-0.3	0.0	-0.6	-0.9	-0.4	-0.3	-0.9	-0.9	-0.1	-0.2
Number of incorrect matches in round	0.2	0.3	0.8	0.1	-0.9	-0.7	-0.9	0.4	0.3	-0.7	-0.8	0.0	-0.4	0.1	0.5
Past tobacco smoking	0.2	0.4	1.2	0.5	0.7	0.3	0.9	0.2	0.7	0.9	0.2	-0.0	0.8	1.1	-0.4
Nervous feelings	0.2	0.4	1.9	-0.1	-0.4	-0.7	-0.1	-1.0	0.2	-0.4	-1.4	-0.8	-0.5	0.3	0.4
Medication: Ramipril	0.2	0.2	0.8	-0.3	-0.4	-0.9	-0.6	-0.2	-0.3	-0.2	-0.4	-0.1	0.1	-0.9	-0.7
Alcohol intake versus 10 years previously	0.2	0.3	1.5	0.7	0.5	-0.6	0.4	-0.1	0.6	0.5	-0.1	-0.3	0.1	0.2	1.2
Father’s age at death	0.2	0.3	1.0	-0.9	-0.3	-0.4	-0.5	-0.3	-1.0	-0.3	-0.5	-0.2	-0.4	-0.4	-0.9
Qualifications: A levels/AS levels or equivalent	0.2	0.4	2.0	0.1	0.8	-0.5	0.8	-0.4	-0.5	0.6	1.4	-0.0	0.2	0.4	-0.9
Mouth/teeth dental problems: Dentures	0.2	0.4	1.1	-0.4	-0.9	1.0	-0.6	0.5	0.3	-0.6	-0.3	0.2	-0.2	1.1	-0.3
Medication: Lansoprazole	0.2	0.2	1.2	0.1	-0.2	-0.5	0.1	1.1	0.3	0.2	0.3	-0.4	0.9	-0.2	0.2
Impedance of arm (left)	0.2	1.2	2.5	-1.0	-1.6	0.1	-1.2	-1.5	-0.1	-1.4	-1.6	0.1	-1.4	-0.2	0.4
Length of working week for main job	0.2	0.2	0.7	-0.2	0.0	-0.8	0.4	-0.5	-0.4	-0.1	0.2	-0.0	-0.0	0.9	0.0
Birth weight of first child	0.2	0.3	1.6	0.0	0.7	-0.4	0.3	-0.5	-0.7	0.4	0.4	0.2	0.0	-0.1	-1.2
Loud music exposure frequency	0.2	0.2	0.7	0.7	0.5	0.5	0.6	-0.8	0.2	0.2	-0.1	0.1	-0.2	-0.2	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.7	-0.8	-0.2	-0.3	-0.4	-0.8	-0.8	-0.2	-0.6	0.1	-0.2	-0.8	0.7
Wheeze or whistling in the chest in last year	0.2	0.4	2.9	0.2	0.5	-1.7	0.1	-0.2	-0.2	0.3	0.5	-0.2	0.3	-0.6	0.4
Qualifications: College or University degree	0.2	0.7	2.8	0.1	0.6	0.5	0.8	-0.6	-0.2	0.3	1.7	0.3	0.1	1.1	-1.4
Neck or shoulder pain in last month	0.2	0.4	1.8	-0.5	-0.2	-0.4	-0.6	-0.1	-0.2	-0.3	-0.6	-0.4	-0.1	-1.3	-1.0
Angina (self-reported)	0.2	0.3	1.2	0.1	0.2	-0.8	-0.1	1.1	0.1	0.1	-0.0	-0.3	0.2	-0.8	0.7
Alcohol intake frequency.	0.2	0.4	0.9	0.8	0.8	0.2	0.6	0.3	1.0	0.7	0.1	0.4	0.6	0.4	0.9
Comparative height size at age 10	0.2	0.9	2.6	-0.5	-0.9	1.6	-0.8	0.4	0.4	-0.7	-1.4	-0.8	-0.5	-0.4	-1.6
Number of full sisters	0.2	0.2	0.6	-0.2	-0.7	0.7	-0.6	-0.0	0.4	-0.6	0.3	0.7	0.2	-0.3	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.9	0.1	-0.6	-0.2	-0.8	-0.9	0.3	-0.6	-0.3	-0.0	-0.4	-0.2	0.9
Smoking status: Previous	0.2	0.3	1.5	-0.0	-0.4	-0.0	-0.5	0.4	-0.5	-0.5	0.2	0.2	-0.5	-0.6	1.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.1	-0.5	-0.5	-0.1	-0.1	-0.0	-0.5	-0.5	-1.0	-0.3	-0.2	-0.1	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.9	0.6	0.4	-0.8	0.3	0.9	0.3	0.6	0.0	-0.1	0.5	-0.3	-0.7
Back pain experienced in last month	0.2	0.3	1.2	-1.1	-0.6	-0.4	-0.5	0.0	-0.6	-0.8	-0.4	-0.5	-0.5	-0.4	-0.1
Medication: Gliclazide	0.2	0.2	0.7	0.3	0.4	-0.0	0.0	0.7	0.1	0.3	0.1	0.8	0.4	-0.8	0.0
Illnesses of father: None of the above (group 1)	0.2	0.2	0.9	0.2	0.1	-0.3	0.8	-0.1	0.7	-0.1	0.2	-0.0	-0.1	1.0	-0.0
Eye problems/disorders: Glaucoma	0.2	0.2	0.6	-0.6	0.1	0.5	0.7	0.8	-0.7	-0.1	0.2	-0.5	-0.1	-0.1	-0.4
Medication: Paracetamol	0.2	0.3	0.9	-0.4	-0.4	-0.3	-0.8	-0.7	0.4	-0.4	-0.5	0.1	0.3	-0.9	0.3
Illnesses of father: High blood pressure	0.2	0.3	0.6	-0.2	-0.3	-0.5	-0.8	-0.6	-0.2	-0.4	-0.7	0.4	-0.6	-0.7	0.2
Alcohol drinker status: Never	0.2	0.2	0.6	0.2	0.7	-0.8	0.8	0.0	0.2	0.2	0.1	0.4	0.1	0.5	0.8
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.7	-0.0	-0.4	-0.6	-0.5	0.9	0.2	-0.1	-0.2	-0.2	0.0	0.7	0.3
Fractured/broken bones in last 5 years	0.2	0.3	1.0	-0.4	-0.4	-0.9	-0.4	-0.5	0.3	-0.1	-0.9	-1.0	-0.2	-0.2	-0.6
Supplements: Calcium	0.2	0.3	1.3	-0.3	0.4	0.6	0.7	-1.1	-0.6	0.1	0.4	0.3	-0.1	-0.1	-0.5
Bipolar Disorder or Schizophrenia	0.1	0.2	0.8	-0.9	-0.4	0.3	-0.5	0.6	-0.0	-0.2	0.1	-0.2	-0.4	-0.4	-0.6
Schizophrenia (2018)	0.1	0.2	0.9	-0.6	-0.3	0.0	-0.5	1.0	0.3	-0.1	-0.1	-0.3	-0.1	0.4	0.2
Alzheimer’s Disease (in father)	0.1	0.1	0.6	0.4	-0.0	0.8	0.4	0.0	-0.2	0.0	-0.0	-0.2	0.1	0.2	-0.0
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.4	-0.2	0.0	-0.2	0.5	-0.3	0.1	-0.3	1.2	0.3	-0.4	0.7	0.7
HDL Cholesterol	0.1	0.2	0.8	-0.2	-0.6	0.5	-0.9	-0.8	0.2	-0.3	-0.2	0.3	-0.2	-0.7	-0.0
LDL Cholesterol	0.1	0.1	0.5	0.6	0.2	-0.1	0.1	0.4	0.2	0.4	0.2	-0.2	0.3	0.7	-0.0
Blood White Count	0.1	0.4	3.2	-0.1	0.5	0.2	0.1	0.2	-0.3	0.3	1.8	0.7	0.4	-0.5	0.2
Height	0.1	2.0	4.8	1.1	1.5	2.2	1.5	1.7	1.1	1.2	1.9	1.8	0.8	0.5	0.1
Systolic Blood Pressure	0.1	0.5	2.9	0.1	0.7	-1.7	0.6	0.5	0.1	0.7	0.3	0.0	0.8	-0.6	0.9
Chronotype (morning person)	0.1	0.3	1.0	0.8	1.0	0.0	0.8	-0.4	0.1	0.6	-0.2	0.7	-0.6	-0.0	0.2
Hair Pigment	0.1	4.1	8.6	2.9	2.4	0.5	2.1	2.1	2.2	2.3	1.3	1.6	2.0	1.8	2.1
Tanning	0.1	1.1	2.2	0.9	1.5	0.3	1.0	1.5	1.1	1.3	1.0	0.8	1.5	0.8	-0.1
Number of treatments/medications taken	0.1	0.2	1.1	-0.2	0.0	-0.7	-0.4	-0.4	-0.4	-0.1	-0.6	-0.3	-0.2	-1.0	-0.2
Sensitivity / hurt feelings	0.1	0.2	0.8	0.5	0.2	0.6	0.3	-0.1	0.6	0.4	-0.9	-0.1	0.2	0.5	0.1
Systolic blood pressure, automated reading	0.1	0.3	1.0	0.6	0.5	0.5	0.7	1.0	0.7	0.6	-0.1	0.3	0.9	-0.1	0.5
Medication for hormone replacement therapy	0.1	0.1	0.5	-0.1	0.0	-0.7	-0.4	0.3	-0.3	0.0	-0.5	-0.5	-0.1	-0.3	-0.1
Medication: Co-codamol	0.1	0.1	0.7	-0.4	0.1	-0.8	0.2	0.3	-0.3	0.0	-0.1	-0.2	0.2	-0.5	0.1
Taking other prescription medications	0.1	0.2	0.6	0.3	-0.0	0.8	-0.1	0.8	0.3	0.1	-0.1	0.7	0.2	-0.8	0.2
Serious illness, injury or assault to yourself	0.1	0.1	0.2	-0.3	-0.1	-0.0	-0.5	-0.1	-0.4	-0.1	-0.4	-0.2	-0.4	-0.4	-0.2
Forced vital capacity (FVC)	0.1	0.3	1.7	-0.3	0.4	0.4	0.3	-0.5	-0.8	0.3	0.4	-0.8	-0.1	-0.3	-1.3
Mouth/teeth dental problems	0.1	0.2	1.0	0.5	0.4	-0.4	-0.2	0.1	-0.3	0.1	0.2	-0.1	-0.1	-0.7	1.0
Allergy	0.1	0.1	0.5	0.0	-0.4	0.2	-0.5	-0.2	0.1	-0.3	-0.3	-0.7	-0.3	0.2	0.1
Pain all over the body in last month	0.1	0.1	0.5	0.2	-0.2	-0.6	-0.4	0.5	0.7	0.1	-0.1	0.1	0.2	0.4	-0.4
Impedance of arm (right)	0.1	0.6	1.4	-0.4	-0.8	0.6	-0.4	-0.9	0.3	-0.9	-1.2	0.8	-1.1	-0.1	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.6	-0.1	0.0	-0.1	-0.3	-0.7	0.2	-0.1	-0.8	-0.2	-0.2	-0.8	0.2
Hair/balding pattern: Pattern 3	0.1	0.2	0.8	-0.3	0.2	-0.0	0.1	0.4	-0.7	0.2	-0.9	-0.6	-0.3	-0.0	-0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	1.3	0.1	0.5	0.7	0.4	-0.2	-0.2	0.5	0.6	-0.6	0.3	-0.5	-1.1
Standing height	0.1	0.5	3.6	-0.2	0.1	1.9	0.1	-0.3	0.0	0.0	0.6	0.7	-0.1	-0.7	-1.1
Peak expiratory flow (PEF)	0.1	0.3	0.9	0.5	0.6	0.9	0.4	-0.7	0.7	0.2	0.6	0.5	-0.3	-0.7	0.4
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.5	-0.7	0.2	-0.6	0.5	-0.3	-0.3	0.2	-0.1	-0.6	0.1	0.4	-0.0
Number of full brothers	0.1	0.2	0.7	-0.7	-0.2	-0.3	0.3	0.0	-0.3	-0.1	-0.3	-0.5	0.1	-0.9	-0.4
Eye problems/disorders: None of the above	0.1	0.1	0.3	0.3	-0.0	0.3	-0.3	-0.2	0.5	-0.0	0.4	0.1	0.2	-0.6	0.1
Overall health rating	0.1	0.3	1.0	0.1	-0.2	-0.1	-0.6	-0.9	0.4	-0.1	-1.0	-0.5	-0.1	-0.2	-0.7
Supplements: Vitamin C	0.1	0.1	0.7	-0.2	-0.3	0.1	-0.3	0.5	-0.3	-0.4	-0.8	0.0	0.0	0.3	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.6	0.4	0.3	0.3	0.7	-0.1	0.3	0.3	-0.4	0.2	0.1	0.1	-0.7
Breast cancer (self-reported)	0.1	0.2	0.5	0.1	-0.5	-0.7	-0.4	0.2	0.1	-0.3	-0.5	-0.4	0.2	0.5	0.2
Number of self-reported non-cancer illnesses	0.1	0.2	1.0	-0.5	-0.2	-0.5	-0.3	-0.2	-0.5	-0.1	-0.6	0.3	-0.1	-1.0	0.4
High cholesterol (Self-reported)	0.1	0.1	0.5	0.5	0.5	0.6	0.7	-0.1	-0.3	0.3	-0.1	0.3	-0.0	0.1	0.4
Cholesterol lowering medication	0.1	0.2	0.5	0.7	0.6	0.5	0.4	0.7	0.0	0.5	0.3	0.3	0.4	0.4	-0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.4	1.2	0.6	0.5	1.1	0.6	0.1	0.2	0.5	0.2	0.9	0.4	-0.8	-0.5
Wears glasses or contact lenses	0.0	0.0	0.0	0.2	0.2	-0.1	0.1	0.0	0.1	0.0	-0.0	0.0	-0.2	-0.1	-0.0

Hub : Genes

MAGEF1

Models

Trait associations