Hub : Genes

MAN1A1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adrenal Gland 0.3397 0.1137 8.1e-03 0.077 NA 0.098 NA 0.092 9.9e-04 NA 2.2e-04 NA 3.5e-04
2 GTEx Artery Aorta 0.1180 0.0450 1.0e-03 0.011 NA 0.062 NA 0.039 7.7e-02 NA 2.4e-04 NA 3.1e-03
3 GTEx Cells Transformed fibroblasts 0.1150 0.0370 4.3e-05 0.043 NA 0.046 NA 0.058 3.3e-04 NA 2.3e-04 NA 3.9e-05
4 GTEx Ovary 0.3180 0.1280 7.8e-03 0.121 NA 0.225 NA 0.124 7.1e-04 NA 3.2e-06 NA 6.1e-04
5 GTEx Spleen 0.1660 0.0710 6.1e-03 0.003 NA -0.004 NA -0.010 2.7e-01 NA 4.2e-01 NA 7.4e-01
6 NTR Blood 0.0210 0.0080 8.1e-05 0.004 0.011 0.014 0.011 0.008 1.1e-02 1.3e-04 1.7e-05 9.4e-05 6.7e-04
7 YFS Blood 0.0637 0.0174 8.9e-14 0.043 0.051 0.042 0.050 0.048 7.0e-14 2.6e-16 1.1e-13 4.9e-16 1.8e-15
8 TCGA Thyroid Carcinoma 0.0440 0.0240 2.1e-03 0.018 0.022 0.015 NA 0.010 5.8e-03 3.1e-03 1.1e-02 NA 3.1e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.9 1.4 6.1 -0.1 -0.0 -1.3 0.6 2.5 0.2 0.7 -1.6
Bipolar Disorder or Schizophrenia 0.5 1.1 6.4 0.5 -0.7 0.1 0.3 2.5 -0.1 0.0 -1.4
Depressed Affect (Nagel 2018) 0.5 1.0 2.2 -0.1 -1.1 0.4 -0.4 1.2 1.5 1.0 -1.2
Depression (Nagel 2018) 0.5 0.8 1.9 0.9 -0.9 0.6 -0.4 -0.3 0.9 1.4 1.2
Intelligence (Savage-Jansen 2018) 0.9 2.9 7.6 -0.4 -1.2 -1.0 -2.3 2.8 1.7 1.3 -1.8
Neuroticism (Nagel 2018) 0.8 2.0 8.1 -1.1 -0.1 -1.5 0.2 1.6 0.6 1.1 -2.9
Schizophrenia (2018) 0.3 0.6 1.6 0.8 -0.9 1.1 -0.2 1.3 -0.3 -0.5 -0.5
Schizophrenia vs Biploar Disorder 1.1 1.5 3.6 1.0 1.5 -0.7 -1.5 -1.9 -1.4 -0.8 0.3
Worry (Nagel 2018) 1.0 2.2 6.9 -1.0 0.6 -2.6 0.7 1.1 0.1 0.7 -2.6
Alzheimer’s Disease (in mother) 0.5 0.6 1.9 -1.4 0.9 -0.9 0.5 0.3 -0.5 -0.1 -0.9
Alzheimer’s Disease (in father) 0.7 0.8 2.6 -0.2 0.5 -1.6 -0.7 0.8 0.6 -0.5 -1.2
Alzheimer’s Disease (including proxy) 0.9 1.3 3.9 -1.2 1.6 -2.0 -0.5 0.3 -0.3 -0.6 -1.1
Crohns Disease (2017) 0.8 1.7 3.5 -0.8 1.9 -0.8 0.6 -1.8 -1.5 -1.4 1.0
Irritable Bowel Disease (IBD) 0.1 0.3 0.6 -0.6 0.6 -0.7 0.6 0.3 -0.2 0.7 0.4
Ulcerative Colitis (UC) 0.8 1.5 5.7 0.4 -0.7 -0.7 0.2 2.2 0.8 2.4 -0.1
Major Depression (MDD) 0.8 0.9 2.3 -1.2 1.5 -1.1 -0.9 0.8 -0.1 -0.5 -0.8
Reaction Time 0.9 1.7 4.8 0.1 -0.6 -0.5 1.3 2.2 1.7 0.9 -1.7
Verbal and Numeric Reasoning (VNR) 0.6 1.6 3.0 0.1 0.1 -1.4 -1.7 1.7 1.0 1.3 -1.4
Breast Cancer 0.4 0.9 3.5 0.0 -0.9 1.6 -0.1 -1.9 -0.2 0.6 0.4
Ovarian Cancer 1.6 2.1 6.7 1.1 0.8 0.6 -1.3 -2.2 -0.6 -1.1 2.6
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.2 0.2 0.6 0.5 -0.7 -0.1 -0.8 0.1 -0.7 0.2 -0.3
Bipolar Disorder (2011) 1.5 1.5 5.7 0.7 -0.6 -0.2 1.5 2.4 0.5 1.1 -1.2
Body Mass Index (BMI) (2010) 1.4 1.9 7.5 0.1 0.7 1.1 0.5 -1.9 -1.2 -1.1 2.7
Coronary Artery Disease (CAD) 0.7 0.8 2.5 -0.9 -0.0 -0.7 0.6 1.6 1.1 0.8 -0.7
Crohns Disease (2012) 1.1 1.8 4.2 -1.3 2.0 -0.5 0.9 -1.3 -1.7 -1.7 0.1
Mean Putamen Volume 0.6 0.7 2.7 0.2 0.6 0.5 -0.7 -0.5 -1.6 -1.1 0.4
Fasting Glucose 0.1 0.1 0.6 0.1 0.1 0.8 0.0 0.5 0.2 0.0 -0.2
HbA1C 0.7 0.8 4.3 -0.4 -0.0 0.9 2.1 -0.6 0.5 0.4 0.4
HDL Cholesterol 0.3 0.6 2.0 1.4 0.7 -1.0 -0.4 0.4 -0.0 -0.3 -0.8
LDL Cholesterol 1.0 1.6 3.4 1.1 -1.6 1.8 0.3 1.1 1.7 1.2 0.1
Lupus 1.0 1.5 5.2 -0.6 1.5 -0.4 -0.1 -2.3 -1.2 -0.3 1.5
Neuroticism (2016) 1.6 2.4 8.7 -1.7 0.2 -1.5 -0.3 1.8 1.2 0.2 -2.9
Primary Biliary Cirrhosis 0.5 0.7 3.8 -0.2 -0.3 0.5 -0.9 0.0 -1.9 -0.6 0.4
Rheumatoid Arthritis 0.5 0.7 2.2 1.5 -0.6 0.8 1.3 -0.6 0.8 0.3 0.2
Schizophrenia (2014) 0.3 0.6 1.9 1.1 -0.6 0.7 -0.2 1.4 -0.3 -0.1 -0.5
Triglycerides 0.1 0.2 0.8 -0.1 0.0 0.3 -0.9 0.4 0.3 0.1 0.5
Type 2 Diabetes (T2D) (2012) 1.8 2.0 4.4 -0.6 -2.1 1.8 1.7 2.0 -0.2 0.8 -0.9
Ulcerative Colitis 1.2 1.8 6.3 -0.4 -0.9 -0.4 0.0 2.5 0.9 2.3 -0.8
Blood Eosinophil Count 0.4 2.8 5.4 1.9 0.9 0.3 -2.3 -1.7 -1.5 -1.7 2.1
Blood Platelet Count 0.2 2.5 11.2 3.3 -1.3 1.4 -0.2 0.4 0.6 2.0 1.0
Blood Red Count 0.2 2.0 11.4 -0.5 -0.4 1.6 3.4 0.0 1.1 -0.4 -0.4
Blood White Count 0.1 0.5 1.3 0.5 -0.3 1.1 0.8 -0.9 0.3 -0.7 0.1
Heel T-Score 0.4 3.3 9.5 1.0 2.0 -0.3 -1.4 -1.2 -2.9 -3.1 0.2
BMI 1.2 6.8 29.9 1.3 -0.1 3.3 -1.4 -2.9 0.6 -1.2 5.5
Height 0.1 1.5 5.0 0.9 -0.7 -0.7 -0.7 1.5 -0.3 1.7 -2.2
Waist Hip Ratio (WHR) 0.4 1.7 4.4 2.1 0.7 0.9 -0.4 0.1 -1.4 -2.0 -1.4
Systolic Blood Pressure 0.3 1.6 4.0 -0.4 -1.9 0.5 -0.1 2.0 1.7 0.7 -1.2
Smoking Status 0.4 1.0 3.1 -1.8 -0.0 -0.5 -0.6 -0.6 -0.9 -1.7 -0.6
Allergy or Eczema 0.1 0.2 1.1 0.3 1.0 -0.7 -0.3 0.2 0.0 0.2 -0.2
Cardiovascular Disease 0.7 2.3 5.4 -0.7 1.5 -0.5 -1.6 -1.9 -0.9 -2.3 1.7
Hypothyroidism (self reported) 0.1 0.3 0.9 0.3 -0.0 -0.4 0.9 0.5 -0.5 -0.2 -0.6
Respiratory disease 0.6 1.4 2.5 -0.2 0.8 -0.1 -1.2 -1.6 -1.4 -1.6 1.4
Type 2 Diabetes (T2D) (2018) 0.4 0.7 2.8 -0.7 0.9 0.1 -0.8 0.8 -0.7 -1.7 -0.1
Lung FEV1/FVC ratio 0.5 2.6 8.8 -3.0 -1.0 1.9 1.5 -0.5 1.6 -1.1 1.2
Lung FVC 1.2 6.0 13.8 -2.1 -0.6 -2.1 -0.8 3.4 3.7 2.7 -2.3
Neuroticism 1.1 2.6 11.1 -1.5 -0.7 -1.2 0.2 2.1 0.7 0.9 -3.3
Chronotype (morning person) 0.3 0.6 1.9 1.3 -0.3 0.7 0.4 -0.2 -1.4 -0.7 0.0
Hair Pigment 0.1 1.4 4.9 0.8 1.1 0.5 -0.7 -1.8 -1.0 -0.1 2.2
Tanning 0.0 0.3 1.0 0.3 -0.1 0.8 -1.0 -0.3 0.1 0.8 -0.1
Hand grip strength (left) 1.0 2.8 10.4 -3.2 -1.0 -0.7 -0.5 2.5 1.8 0.0 -0.7
Number of treatments/medications taken 1.2 2.1 8.5 -0.6 -1.4 2.9 -0.6 -1.3 -0.5 -0.7 1.7
Average weekly spirits intake 1.6 2.0 4.6 1.9 -1.0 2.0 -2.1 -0.8 0.9 0.7 1.1
Sensitivity / hurt feelings 0.9 1.6 5.2 -1.2 1.4 -2.3 0.4 0.7 0.9 0.7 -1.5
Frequency of depressed mood in last 2 weeks 0.5 0.8 2.4 -0.2 -0.3 -0.5 0.8 -0.7 0.8 1.6 1.2
Hearing difficulty/problems: Yes 0.5 0.8 2.6 0.5 1.1 -1.6 -0.9 -0.2 0.5 0.7 1.1
Relative age of first facial hair 0.2 0.5 1.0 -1.0 0.2 -0.7 -0.2 0.3 -1.0 -0.7 -1.0
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 0.4 0.6 -0.3 0.4 -0.3 0.6 -0.4 -0.4 -0.6
Ever used hormone-replacement therapy (HRT) 0.9 1.1 2.8 1.0 -0.4 1.3 -1.1 -1.7 -0.3 0.4 1.5
Ever had hysterectomy (womb removed) 1.6 1.8 7.5 0.3 0.2 1.1 0.3 -2.7 -1.2 -0.7 1.9
Systolic blood pressure, automated reading 0.3 0.9 1.7 0.2 -1.3 1.0 -1.3 1.2 0.6 0.8 -0.9
Eye problems/disorders: Diabetes related eye disease 1.0 1.1 2.8 -1.0 -1.0 0.1 -1.6 1.7 0.9 -0.7 -0.4
Angina 1.4 1.8 3.9 1.6 -0.4 1.8 0.1 -2.0 -1.1 -1.0 1.4
Medication for hormone replacement therapy 1.3 1.4 4.6 0.7 0.4 0.7 -1.2 -1.6 -1.3 -0.4 2.2
Vitamin and mineral supplements 1.1 1.5 5.2 -0.3 -0.6 0.8 1.0 1.2 2.3 1.9 0.0
Supplements: Zinc 0.8 0.8 2.0 0.4 1.4 -1.3 0.3 -0.3 -0.4 -1.1 -1.2
Medication: Co-codamol 2.3 2.7 8.0 2.1 0.0 -0.5 -2.8 -0.4 -2.2 -1.1 -1.6
Medication: Metformin 0.2 0.2 0.7 -0.5 -0.1 0.8 0.1 0.8 0.2 -0.0 0.4
Diabetes (father) 0.7 0.8 3.0 -0.1 -0.2 1.7 0.1 -0.4 -1.2 -1.1 0.8
Diabetes (mother) 0.3 0.4 1.0 -0.7 -0.6 0.3 0.6 -0.1 -0.6 -0.8 -1.0
Severe depression (siblings) 0.5 0.6 2.7 -0.7 0.5 -1.0 1.6 -0.4 -0.1 -0.2 -0.0
Pack years adult smoking proportion 0.7 1.1 2.5 0.6 -1.4 0.5 0.9 1.0 1.6 1.1 -0.6
Impedance of leg (right) 0.4 2.2 5.1 1.3 -1.4 0.7 2.0 1.1 -0.1 1.7 -2.2
Leg fat-free mass (left) 0.3 1.8 6.3 -0.5 0.4 1.2 -1.9 -0.9 0.1 -1.3 2.5
Trunk fat percentage 1.1 4.3 15.1 2.0 -0.4 3.0 -1.8 -1.6 0.2 0.2 3.9
Hand grip strength (right) 1.3 3.6 13.2 -3.6 -1.2 -0.8 -0.3 2.7 1.8 0.1 -1.5
Townsend deprivation index at recruitment 0.6 0.8 1.7 -0.3 0.9 -1.3 1.2 -0.6 -0.7 -0.4 -1.0
Current tobacco smoking 0.7 1.1 4.7 -0.2 0.6 -0.7 -0.7 -2.2 -1.5 -0.9 0.2
Average weekly fortified wine intake 1.1 1.3 4.5 0.9 -1.5 0.1 -0.0 1.0 1.3 2.1 -0.1
Maternal smoking around birth 0.5 0.8 3.2 0.5 0.5 0.5 -0.3 -1.2 -0.8 -0.2 1.8
Fed-up feelings 1.0 1.9 4.9 -0.0 -1.5 -0.0 -0.3 1.8 2.2 1.9 -1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 1.6 0.6 0.1 -0.6 -1.2 0.1 1.1 1.3 0.6
Relative age voice broke 0.2 0.3 0.8 -0.3 -0.8 0.9 0.5 -0.3 0.1 0.6 0.7
Taking other prescription medications 0.2 0.3 0.9 -0.2 -1.0 0.9 -0.6 -0.3 -0.5 -0.6 -0.0
Age when periods started (menarche) 0.7 1.7 7.7 0.4 -0.2 -1.0 1.2 1.8 -0.3 0.1 -2.8
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 1.8 0.6 0.4 0.3 -1.3 -1.0 -0.9 -0.7 0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 3.6 -0.1 0.8 -0.2 -0.7 -1.2 -1.9 -1.5 1.0
Tinnitus: Yes, but not now, but have in the past 0.7 0.7 3.6 0.6 0.3 -0.2 -1.9 -0.2 -1.0 -0.8 0.5
Qualifications: CSEs or equivalent 0.1 0.1 0.4 -0.0 0.7 0.4 -0.3 -0.4 -0.1 -0.3 0.3
Serious illness, injury or assault to yourself 0.7 0.9 2.8 -0.2 0.4 -1.7 1.0 0.5 0.8 1.3 -0.7
High blood pressure 0.8 2.3 7.9 -0.1 1.2 0.2 -1.7 -2.1 -0.5 -1.1 2.8
Hayfever, allergic rhinitis or eczema 0.1 0.2 0.6 0.5 0.8 -0.4 0.1 -0.0 0.5 0.3 0.2
Multivitamins +/- minerals 0.4 0.6 1.5 1.0 0.2 0.1 -0.6 -1.0 -1.2 -0.5 0.5
Stomach or abdominal pain in last month 0.6 0.7 2.9 -1.4 0.1 -0.5 -0.2 0.8 0.4 0.0 -1.7
Supplements: Glucosamine 0.1 0.2 0.5 0.3 0.3 -0.3 -0.6 -0.7 -0.3 0.1 0.5
Diverticular disease/diverticulitis (self-reported) 0.9 1.0 3.6 -0.2 1.4 -0.9 -1.9 -0.7 -0.8 0.1 0.7
Medication: Atenolol 0.4 0.5 1.5 1.2 -0.8 0.5 -0.7 -0.1 0.6 0.2 0.6
Medication: Levothyroxine sodium 0.0 0.1 0.3 -0.2 -0.2 0.0 -0.1 0.5 -0.4 -0.1 -0.3
Sitting height 0.1 0.6 1.5 -0.8 -0.3 0.2 0.1 1.2 1.0 -0.7 -1.1
Chronic bronchitis/emphysema (father) 0.5 0.6 1.0 0.7 0.9 -0.8 -0.9 -0.7 -0.5 0.5 1.0
High blood pressure (mother) 1.2 1.7 4.1 -0.8 1.5 -0.4 -1.3 -2.0 -1.3 -1.7 0.5
Body mass index (BMI) 1.4 6.1 26.4 1.2 0.3 2.5 -2.7 -2.5 0.3 -0.8 5.1
Impedance of leg (left) 0.3 1.7 3.5 1.2 -1.1 0.4 1.9 0.8 -0.3 1.6 -1.9
Leg predicted mass (left) 0.3 1.8 6.5 -0.4 0.5 1.2 -1.9 -1.0 0.1 -1.3 2.6
Trunk fat mass 1.0 4.5 15.7 1.7 -0.3 3.0 -2.4 -1.6 0.2 -0.1 4.0
Waist circumference 1.0 3.5 9.3 2.2 -0.1 2.4 -2.4 -1.4 -0.2 -0.8 3.0
Number of incorrect matches in round 0.8 1.4 4.3 1.0 0.5 -0.3 -0.6 -2.1 -1.2 0.3 1.8
Past tobacco smoking 0.5 0.8 2.5 1.0 0.4 0.8 0.6 -1.5 0.0 0.3 1.6
Alcohol usually taken with meals 1.4 2.3 4.0 1.7 1.0 -2.0 0.0 1.9 1.5 0.7 -2.0
Nervous feelings 2.0 3.6 10.9 -0.1 -0.4 -2.1 0.5 2.8 0.5 2.3 -3.3
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 2.1 0.3 -0.0 -0.9 -0.1 -0.3 0.4 1.5 0.7
Hearing difficulty/problems with background noise 0.6 0.9 2.6 1.4 -0.6 -0.4 -1.6 0.9 0.9 1.0 0.4
Hair/balding pattern: Pattern 2 0.6 0.7 1.4 -0.4 -1.2 0.7 -1.0 0.5 1.1 1.0 -0.6
Had menopause 0.7 0.9 5.0 2.2 -0.3 0.5 0.2 -0.0 0.5 0.9 0.7
Had other major operations 0.6 0.8 3.3 1.8 0.2 -0.2 -1.5 -0.5 -0.1 0.2 0.3
Forced vital capacity (FVC) 1.3 4.8 13.4 -1.3 -1.5 -1.0 0.1 3.7 2.8 2.0 -2.9
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.4 1.9 0.2 -0.1 -0.0 -0.7 -0.0 -0.9 -1.4 0.1
Ever unenthusiastic/disinterested for a whole week 0.8 1.0 2.1 1.0 -0.3 1.2 -0.7 -1.4 0.9 0.3 1.3
Qualifications: None of the above 0.4 0.9 3.8 -0.0 0.6 1.1 -0.6 -2.0 -1.0 -0.7 0.5
Financial difficulties in last 2 years 0.4 0.6 1.8 -1.3 0.3 -0.6 -1.2 -0.6 0.1 -0.8 0.2
Mouth/teeth dental problems 0.8 1.2 2.3 -1.1 1.2 -1.5 1.5 0.5 0.7 1.4 -0.1
Heart attack 1.2 1.5 6.0 0.8 -2.4 2.3 0.3 0.1 0.3 0.3 0.3
Allergy 0.1 0.2 0.4 -0.3 -0.0 0.1 0.6 -0.5 -0.3 0.6 0.4
Pain all over the body in last month 2.2 2.3 3.9 2.0 1.9 -0.9 -2.0 -1.9 -0.6 -0.0 1.5
Diabetes (self-reported) 0.5 0.8 1.8 -0.6 0.9 -0.2 -1.0 1.3 -0.0 -1.3 -0.8
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.5 -0.7 -0.6 1.2 -0.2 -1.0 0.3 -0.4 0.8
Medication: Ramipril 0.7 0.9 3.4 0.3 1.5 -0.2 1.8 -0.6 0.6 -0.3 0.8
Medication: Simvastatin 0.9 1.3 3.0 -0.9 1.5 -1.3 -1.3 -0.1 -1.1 -1.7 0.2
Fluid intelligence score 0.7 1.4 5.8 0.9 0.1 -0.7 -2.4 1.3 0.9 0.6 -1.3
Illnesses of siblings 0.9 1.3 2.7 1.6 0.1 -1.1 -0.1 1.6 0.6 1.0 -1.6
Neuroticism score 0.7 1.4 4.3 -0.8 -0.3 -1.1 0.8 1.1 0.9 1.5 -2.1
Weight 0.8 4.1 16.8 0.9 0.0 2.4 -2.5 -1.6 0.1 -0.7 4.1
Impedance of arm (right) 1.1 5.2 12.5 -0.2 -1.2 -1.4 3.2 2.5 1.2 2.7 -3.5
Arm fat percentage (right) 0.9 3.5 14.0 1.2 -0.5 2.5 -1.9 -1.1 1.2 0.3 3.7
Trunk fat-free mass 0.2 1.2 4.5 -0.1 0.1 1.1 -2.1 -0.2 -0.1 -1.3 1.5
Hip circumference 1.0 4.2 14.5 1.7 -0.4 2.5 -2.7 -1.6 0.2 -0.3 3.8
Time employed in main current job 1.4 1.6 4.4 1.4 -1.1 2.1 -0.3 -0.9 -1.0 -1.3 1.4
Alcohol intake versus 10 years previously 0.4 0.6 2.3 1.5 -0.7 1.0 -0.4 -0.1 0.2 0.8 0.7
Father’s age at death 0.8 1.1 2.5 -1.2 1.5 -1.6 0.8 0.4 -1.0 -0.3 -0.6
Worrier / anxious feelings 0.7 1.3 2.8 -1.0 0.7 -1.6 1.4 0.4 0.8 1.7 -0.9
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.3 6.2 0.6 0.8 -1.6 -2.5 0.7 0.2 0.3 -0.6
Falls in the last year 0.7 0.9 3.9 1.3 -0.0 0.5 -0.4 -0.8 -0.7 0.4 2.0
Hair/balding pattern: Pattern 3 0.9 1.3 2.7 -0.2 1.3 -0.8 1.1 -1.3 -1.6 -1.4 0.9
Number of live births 1.3 1.8 7.4 -0.2 -0.3 -1.3 -0.6 2.0 -0.3 -0.7 -2.7
Forced expiratory volume in 1-second (FEV1) 1.4 4.7 11.1 -2.2 -1.5 -0.3 0.7 3.3 3.3 1.4 -2.4
Pulse rate 2.3 3.8 8.6 -0.6 -1.5 0.1 1.6 2.4 2.4 2.2 -2.9
Happiness 0.7 0.8 3.0 1.2 0.9 0.1 0.5 -0.3 1.7 1.0 0.2
Noisy workplace 1.2 1.4 2.9 0.2 0.2 0.9 1.7 -1.6 -1.6 -0.9 1.4
Qualifications: A levels/AS levels or equivalent 0.5 1.0 3.4 0.4 -0.3 -0.9 -0.7 1.9 0.4 1.4 -0.9
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 1.1 1.1 0.4 0.2 -0.2 -0.3 -0.9 -0.7 -0.0
Mouth/teeth dental problems: Dentures 1.5 2.5 8.5 0.8 0.0 0.4 -2.5 -0.7 -2.0 -2.9 -0.2
Asthma 0.1 0.3 0.5 0.7 -0.1 0.3 -0.4 -0.4 -0.7 -0.4 0.7
Medication: Ibuprofen (e.g. Nurofen) 1.2 1.5 6.3 -1.6 -1.3 2.5 1.0 0.4 -0.1 0.4 -0.7
Medication: Cholesterol lowering 0.1 0.1 0.4 -0.6 0.0 -0.4 -0.2 0.3 0.6 0.1 -0.1
Depression (self-reported) 1.3 1.5 3.6 -1.9 0.1 -1.8 1.2 0.8 0.7 -0.0 -1.7
Medication: Lansoprazole 0.4 0.4 2.0 -1.4 -0.1 -0.0 -1.1 0.3 -0.0 0.0 0.0
Prospective memory result 0.7 0.9 2.9 -1.7 0.5 -0.4 1.1 -0.8 -1.2 -0.6 0.4
Lung cancer (father) 0.4 0.4 1.2 1.1 -0.0 1.1 -0.3 -0.7 -0.4 -0.2 0.3
Illnesses of mother 1.6 1.9 4.8 0.4 -1.1 0.4 1.8 2.2 2.2 0.9 -0.7
Forced expiratory volume in 1-second (FEV1), Best measure 1.3 4.1 10.6 -2.2 -1.3 -0.3 1.2 3.0 3.2 1.7 -1.4
Pulse wave Arterial Stiffness index 2.7 3.1 8.9 -0.1 3.0 -1.7 -0.2 -2.1 -2.3 -1.7 0.8
Impedance of arm (left) 1.0 4.4 12.5 -0.2 -0.7 -1.7 3.0 2.5 0.6 1.9 -3.5
Arm fat mass (right) 1.0 4.1 17.1 1.1 -0.1 2.5 -2.2 -1.5 0.6 -0.4 4.1
Trunk predicted mass 0.2 1.2 4.4 -0.1 0.1 1.0 -2.1 -0.2 -0.1 -1.3 1.5
Standing height 0.1 0.8 2.9 -0.7 -0.7 -0.0 0.1 1.5 -0.6 0.0 -1.7
Length of working week for main job 0.9 1.0 2.8 -0.2 -1.1 1.6 -0.2 -1.0 0.8 0.0 1.7
Exposure to tobacco smoke at home 0.6 0.6 1.4 0.7 -0.2 1.2 -0.9 -1.1 -0.7 -0.6 0.6
Breastfed as a baby 1.5 1.9 4.5 1.2 0.3 0.9 -2.1 -1.9 -1.4 0.1 1.5
Tense / ‘highly strung’ 0.7 1.1 5.5 -1.0 -0.8 -0.3 2.3 -0.5 0.0 1.1 -0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 1.3 1.9 4.8 -0.8 -0.7 -1.7 0.7 2.0 0.4 1.4 -2.2
Hair/balding pattern: Pattern 4 0.4 1.0 2.0 -0.4 -1.4 1.0 -0.5 1.2 0.8 0.1 -1.4
Birth weight of first child 0.2 0.4 1.0 0.9 0.3 0.3 0.4 0.3 1.0 -0.4 0.9
Peak expiratory flow (PEF) 0.7 1.6 4.5 -1.6 -0.8 0.7 0.5 1.9 2.1 -0.2 -0.7
Pulse wave reflection index 3.1 3.8 8.2 1.0 2.1 -0.8 0.1 -2.9 -2.9 -1.9 2.2
Ever highly irritable/argumentative for 2 days 0.3 0.4 1.0 0.5 0.4 0.9 0.2 -0.8 -0.3 0.2 1.0
Loud music exposure frequency 2.8 3.0 9.2 0.1 -0.9 -0.4 2.2 3.0 2.4 1.5 -1.2
Qualifications: O levels/GCSEs or equivalent 0.2 0.4 0.9 0.8 -0.3 0.3 -0.3 0.6 0.9 0.9 0.1
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 0.9 0.9 -0.8 0.4 0.9 0.8 0.6 1.0 -0.3
Blood clot in the leg (DVT) 1.1 1.4 3.3 1.1 -1.3 0.4 -1.5 1.8 0.3 1.0 -1.2
Medication: Paracetamol 0.5 0.8 3.0 0.1 -1.4 1.7 -1.2 0.2 -0.1 -0.0 -0.5
Headache pain in last month 0.5 0.9 3.2 -1.1 -1.8 1.0 0.7 0.0 0.6 0.8 -0.2
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 0.8 0.0 -0.5 0.6 0.5 0.4 -0.8 -0.3 -0.9
Glaucoma (self-reported) 0.7 0.8 3.1 -0.4 0.5 1.1 -0.3 -1.8 0.3 0.1 1.3
Gout (self-reported) 1.6 2.2 5.7 -0.6 2.2 -2.4 1.2 -1.3 -1.3 -1.2 0.6
Hypothyroidism/myxoedema (self-reported) 0.3 0.6 1.6 -0.2 -0.1 -0.5 -0.6 0.6 -1.3 -1.0 -0.9
Medication: Amlodipine 0.3 0.4 1.5 0.6 0.7 0.0 0.5 -0.7 0.4 -0.5 1.2
Medication: Ventolin 100micrograms inhaler 1.0 1.3 3.4 -1.2 0.8 0.6 0.3 -1.8 -0.4 -1.9 1.1
Birth weight 0.5 1.1 3.5 -0.6 -0.8 0.0 1.1 0.8 1.6 1.9 -0.3
Chronic bronchitis/emphysema (mother) 0.9 1.1 3.0 0.8 -0.4 0.2 0.1 -1.5 0.1 1.5 1.7
High blood pressure (siblings) 1.4 2.0 3.9 -1.3 1.1 -0.8 -0.1 -2.0 -1.5 -1.9 1.5
Forced vital capacity (FVC), Best measure 0.8 3.0 8.6 -1.6 -0.9 -1.1 -0.1 2.9 2.4 1.5 -1.7
Body fat percentage 1.2 4.8 16.4 2.1 -0.4 3.1 -2.2 -1.5 0.5 0.3 4.0
Leg fat percentage (right) 1.8 6.4 18.7 2.5 -0.7 3.6 -2.9 -1.9 0.7 0.4 4.3
Arm fat-free mass (right) 0.6 3.0 7.6 0.3 0.7 1.4 -2.7 -1.4 -0.9 -1.9 2.8
Exposure to tobacco smoke outside home 0.3 0.4 1.9 -0.2 -1.4 0.8 0.1 0.1 0.8 0.5 -0.4
Comparative body size at age 10 0.6 1.5 5.4 0.3 -0.1 1.1 -2.3 -1.2 0.6 -0.5 1.9
Number of full brothers 1.3 1.7 3.8 -0.3 -1.2 -0.1 0.8 1.9 1.9 1.1 -1.7
Worry too long after embarrassment 1.3 2.2 7.2 -0.5 -0.9 -0.6 0.5 1.5 1.2 2.4 -2.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.9 1.1 4.7 0.9 1.0 -2.2 0.2 0.6 0.1 1.3 -0.4
Wheeze or whistling in the chest in last year 0.5 0.8 2.5 0.8 -0.0 0.6 -0.0 -1.6 -1.0 -0.4 1.3
Number of children fathered 0.5 0.5 1.1 -0.1 0.8 -0.6 -0.9 -0.7 -0.1 -0.8 1.1
Reason for reducing amount of alcohol drunk: Health precaution 2.3 2.7 6.6 -1.0 1.7 -0.7 -1.2 -1.7 -2.6 -2.4 -0.2
Age at first live birth 1.5 2.6 7.2 -2.7 0.8 -2.3 2.1 1.2 0.1 0.7 -1.1
Pulse wave peak to peak time 2.7 3.1 8.8 0.1 -3.0 1.7 0.2 2.2 2.1 1.8 -0.9
Health satisfaction 0.2 0.3 0.8 0.8 0.3 -0.1 -0.9 0.3 0.8 0.0 -0.0
Shortness of breath walking on level ground 2.4 2.8 8.3 -0.2 2.9 -1.7 -0.3 -2.2 -0.8 -1.3 2.0
Qualifications: College or University degree 1.4 4.4 11.7 1.8 -1.6 -1.1 0.2 3.4 2.3 3.1 -1.3
Eye problems/disorders: None of the above 0.7 0.8 2.2 -0.7 1.1 -1.0 0.7 -0.8 -1.5 -0.7 0.3
Mouth/teeth dental problems: Loose teeth 0.4 0.5 1.6 0.4 -1.3 1.1 -0.3 -0.6 0.6 0.4 0.5
Emphysema/chronic bronchitis 1.0 1.1 4.3 -0.8 -1.1 -0.5 -0.6 0.9 1.1 -0.5 -2.1
Medication for pain relief, constipation, heartburn 1.1 1.8 8.5 0.9 1.3 -2.9 0.9 1.0 0.5 0.2 -1.1
Neck or shoulder pain in last month 0.2 0.3 1.1 -0.1 0.2 0.1 -0.5 -0.6 -0.7 -1.1 -0.3
Medication: Blood pressure 0.3 0.6 2.9 0.1 0.5 0.4 0.2 -1.1 0.5 -0.1 1.7
Angina (self-reported) 1.3 1.7 4.2 1.7 -0.4 1.7 0.3 -2.1 -1.0 -0.8 1.3
Migraine (self-reported) 0.6 0.8 2.9 -0.4 -1.7 1.1 0.5 0.9 0.1 0.4 -0.7
Medication: Ibuprofen 1.1 1.3 5.8 -1.6 -0.9 2.4 0.9 0.0 -0.1 0.3 0.1
Medication: Allopurinol 0.9 1.2 3.8 -0.9 0.8 -0.8 1.4 -0.7 -1.0 -1.9 0.3
Medication: Omeprazole 0.2 0.3 0.6 0.1 -0.8 0.7 0.1 -0.2 0.8 0.2 0.3
Medication: Seretide 50 evohaler 0.2 0.3 0.7 -0.8 0.2 -0.1 -0.2 0.8 0.7 -0.5 -0.1
Mean time to correctly identify matches 0.8 1.5 3.3 -0.5 -0.7 -0.4 1.4 1.8 1.5 0.8 -1.8
Heart disease (mother) 1.2 1.4 4.9 -0.4 -0.4 1.4 -0.5 -1.8 -2.2 -0.9 -0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 5.0 0.3 -1.5 2.2 0.4 -0.6 0.5 -0.2 0.9
Whole body fat mass 1.2 5.0 18.1 1.8 -0.3 3.0 -2.7 -1.6 0.3 -0.2 4.3
Leg fat mass (right) 1.5 5.8 21.7 1.8 -0.1 3.2 -2.6 -2.1 0.4 -0.4 4.7
Arm predicted mass (right) 0.6 2.8 7.5 0.0 0.6 1.4 -2.6 -1.4 -0.9 -1.8 2.7
Pulse rate, automated reading 2.3 7.4 17.6 -0.7 -2.3 0.5 1.0 3.8 3.4 4.2 -2.9
Alcohol intake frequency. 0.3 0.6 1.3 -0.6 0.5 0.3 0.9 -1.1 -1.1 -0.8 0.5
Comparative height size at age 10 0.1 0.5 1.4 0.6 -0.8 1.2 -1.0 0.2 -0.6 -0.5 0.2
Number of full sisters 0.8 1.0 2.3 -1.4 0.9 -1.3 -0.0 -0.5 -0.8 -1.5 0.3
Suffer from ‘nerves’ 1.7 2.7 8.7 -1.0 0.6 -2.5 1.4 1.6 -0.3 0.8 -3.0
Overall health rating 0.6 1.4 6.5 0.8 0.3 0.4 -2.5 -1.3 -1.1 -0.6 0.6
Chest pain or discomfort 0.6 0.8 2.0 1.0 -1.4 1.3 -1.0 -0.4 -0.8 0.2 -0.0
Had major operations 1.1 1.3 5.8 0.9 -0.8 -0.5 -0.2 2.4 1.1 0.8 -1.1
Age at last live birth 1.0 1.5 5.5 -1.3 0.7 -2.3 0.9 1.3 -0.6 0.8 -1.0
Family relationship satisfaction 0.6 0.7 1.7 0.7 0.9 0.2 -0.1 -0.7 1.1 0.8 1.3
Leg pain on walking 0.8 1.0 3.3 0.7 0.4 0.8 -1.1 -1.4 -0.4 0.5 1.8
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.2 2.3 1.1 0.4 0.6 -1.5 -1.5 -0.3 -1.3 1.3
Commuting to job workplace: Car/motor vehicle 0.7 0.8 2.0 -0.3 1.4 -1.1 -0.9 -1.4 -0.3 -0.4 0.7
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 1.7 -1.1 0.1 -1.3 0.4 1.1 0.3 0.2 -0.9
Medication: Aspirin 2.1 2.8 6.9 1.2 -0.2 1.7 -2.6 -1.8 -0.8 -0.9 2.4
Supplements: Vitamin C 1.5 1.8 6.5 0.8 1.4 -0.8 -0.7 -1.4 -1.6 -2.5 0.4
Knee pain experienced in last month 1.3 2.0 5.8 0.8 -1.0 2.4 -1.3 -1.9 0.0 0.4 1.7
Hypertension (Self-reported) 0.8 2.3 8.6 -0.1 1.4 -0.2 -1.8 -2.0 0.0 -0.5 2.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.2 0.4 -0.6 0.5 0.1 0.1 -0.5 -0.7 -0.6 -0.1
Illnesses of father: Heart disease 0.8 1.1 2.4 1.1 -0.5 0.9 0.1 -0.9 -1.3 1.6 1.4
Illnesses of siblings: Diabetes 0.1 0.1 0.2 -0.3 -0.3 -0.1 -0.4 0.3 -0.0 -0.4 0.1
Smoking status: Previous 0.4 0.5 1.6 -0.9 -0.1 -0.4 -0.1 1.3 -0.1 -0.5 -1.2
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.9 3.2 -0.4 -1.8 1.0 1.0 0.3 -0.2 -0.9 -0.9
Whole body fat-free mass 0.3 1.7 4.8 -0.3 0.4 1.2 -2.1 -0.8 -0.2 -1.5 2.2
Leg fat-free mass (right) 0.3 1.8 6.7 -0.6 0.6 0.9 -1.8 -1.1 -0.0 -1.4 2.6
Arm fat percentage (left) 0.8 3.4 14.1 1.4 -0.2 2.3 -2.0 -1.0 0.9 0.2 3.8
Average weekly red wine intake 0.8 1.2 3.2 -0.4 1.0 -1.7 -0.9 1.8 0.2 0.1 -1.3
Handedness (chirality/laterality): Left-handed 1.1 1.3 7.4 0.3 0.6 -0.7 -2.7 -0.4 -1.1 -0.8 -0.1
Mood swings 0.5 0.9 1.9 -1.2 -0.6 -0.4 -0.2 1.3 1.1 0.2 -1.4
Loneliness, isolation 0.4 0.5 1.7 0.1 -0.4 -0.2 -0.9 0.6 1.3 0.9 0.2
Long-standing illness, disability or infirmity 0.6 0.9 1.7 -0.7 -0.5 1.1 -1.3 -0.9 -1.2 -1.1 -0.4
Ever had bowel cancer screening 0.6 0.7 1.3 0.0 1.2 -0.8 -1.0 -0.6 -1.1 0.4 0.8
Diabetes diagnosed by doctor 0.4 0.7 2.9 -0.6 0.1 0.2 -1.1 1.7 0.1 -0.7 -0.7
Ever had stillbirth, spontaneous miscarriage or termination 1.9 2.1 5.2 1.1 1.3 -0.1 -1.1 -2.1 -1.5 -0.9 2.3
Friendships satisfaction 0.5 0.7 1.9 -1.0 0.1 -0.1 -1.0 0.9 0.8 -0.0 -1.4
Qualifications: nursing, teaching 0.8 1.3 3.3 0.8 1.2 -1.8 -0.9 1.3 0.4 0.5 -1.3
Commuting to job workplace: Walk 1.2 1.3 7.1 -0.8 -0.8 0.6 0.4 1.2 -0.4 -0.5 -2.7
Eye problems/disorders: Cataract 0.6 0.7 1.8 0.8 -0.5 1.2 -0.4 0.0 -0.6 -0.8 -1.3
Mouth/teeth dental problems: Mouth ulcers 0.7 1.2 3.6 0.7 -1.5 1.9 -0.6 -0.5 1.5 -0.1 0.1
Medication for cholesterol 2.6 4.0 8.3 -1.5 -0.8 -1.3 1.6 2.5 2.5 2.0 -2.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.4 1.9 1.4 -0.3 0.3 -0.9 -0.2 0.5 0.4 -0.0
Back pain experienced in last month 1.1 1.6 4.8 0.1 -0.7 0.1 -1.1 2.2 1.8 1.8 -0.5
Mineral and other dietary supplements 0.7 0.9 3.1 -0.1 0.1 0.2 0.7 1.8 1.5 0.5 -1.1
Breast cancer (self-reported) 0.7 0.8 3.8 0.7 0.7 0.1 -1.9 -0.5 -0.3 0.3 1.0
Asthma (self-reported) 0.1 0.2 0.4 0.6 -0.3 0.5 -0.0 -0.4 -0.4 -0.2 0.6
Osteoporosis (self-reported) 1.9 2.3 11.2 -1.9 -0.7 -0.5 0.6 1.6 0.5 0.1 -3.3
Osteoarthritis (self-reported) 1.7 2.1 5.6 1.0 -0.4 1.7 -1.2 -2.0 -1.4 -0.4 2.4
Medication: Aspirin 2.6 3.4 10.0 1.5 -0.3 1.7 -3.2 -1.9 -0.5 -0.8 2.8
Medication: Gliclazide 0.4 0.5 1.1 -0.8 1.0 -0.8 -0.6 0.1 0.1 -1.0 0.0
Illnesses of father: None of the above (group 1) 0.3 0.4 1.1 0.2 -0.6 0.2 0.3 0.8 0.9 -0.2 -1.0
Smoking status: Current 0.9 1.5 5.1 -0.5 0.8 -0.9 -1.0 -2.2 -1.7 -1.2 0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.5 7.3 0.3 -1.7 1.6 -1.3 0.8 2.7 2.1 1.1
Whole body water mass 0.3 1.8 5.2 -0.3 0.5 1.0 -2.2 -0.9 -0.2 -1.5 2.3
Leg predicted mass (right) 0.3 1.7 6.2 -0.5 0.6 0.9 -1.9 -1.0 -0.0 -1.4 2.5
Arm fat mass (left) 1.1 4.3 18.1 1.2 -0.1 2.6 -2.2 -1.5 0.7 -0.3 4.3
Number of self-reported non-cancer illnesses 0.2 0.3 1.9 -0.0 -0.3 1.4 0.5 -0.2 -0.2 -0.3 -0.0
Average weekly champagne plus white wine intake 0.8 1.1 2.7 1.6 -0.3 0.4 0.2 0.9 1.3 1.0 -1.5
Miserableness 1.7 2.9 6.5 -0.5 -2.5 1.2 0.1 2.1 2.3 1.6 -1.5
Guilty feelings 2.0 2.9 10.4 -0.4 -0.7 -1.0 1.4 1.5 1.9 3.2 -2.0
Wears glasses or contact lenses 1.1 1.2 4.7 1.4 0.5 0.6 1.2 -0.6 -0.5 2.2 0.8
Ever taken oral contraceptive pill 0.4 0.4 0.9 0.9 0.3 0.1 -0.9 0.0 -0.8 -0.9 -0.4
Hearing aid user 0.4 0.4 1.2 -0.4 -0.4 -0.7 0.4 0.8 1.1 0.7 0.1
Mother’s age at death 0.5 0.6 2.6 0.2 0.0 1.0 0.2 -1.1 -0.3 -0.3 1.6
Financial situation satisfaction 0.9 1.1 4.0 -1.2 2.0 -1.4 -0.8 -0.5 0.2 -0.4 0.8
Tinnitus: Yes, now most or all of the time 0.7 0.8 1.9 -0.1 1.2 -1.4 -0.2 0.8 -0.9 -0.6 -1.2
Commuting to job workplace: Public transport 0.6 0.7 1.7 1.3 1.1 -1.3 0.0 0.8 -0.3 0.7 0.0
Eye problems/disorders: Glaucoma 0.5 0.6 1.5 0.2 -0.0 1.2 -1.2 -0.7 0.6 0.3 0.8
Medication: Blood pressure 0.6 1.2 3.1 0.7 -0.0 1.2 -1.4 -1.1 -0.8 -1.1 1.7
Pain type(s) experienced in last month: Hip pain 0.6 0.8 2.1 -0.3 -1.0 1.4 -1.1 -0.4 0.6 -0.4 1.0
Supplements: Fish oil (including cod liver oil) 0.8 1.1 2.8 -0.7 -0.6 0.5 -0.3 -1.6 -1.7 -0.5 1.4
High cholesterol (Self-reported) 0.3 0.6 2.5 0.9 0.4 -1.0 -1.6 0.0 -0.3 -0.4 0.0
Medication: Bendroflumethiazide 1.9 2.9 8.1 -0.1 1.6 0.5 -1.7 -2.7 -1.1 -0.7 2.8
Medication: Paracetamol 0.7 1.0 4.3 -0.2 -1.0 2.1 -1.2 -0.7 -0.6 -0.1 0.7
Medication: Lisinopril 0.8 1.1 2.8 1.0 -0.2 0.9 -1.7 -1.2 -0.2 -0.5 1.5
Medication: Atorvastatin 0.7 0.8 1.7 1.3 0.4 0.6 -0.7 -1.2 -1.1 -0.8 0.7
Illnesses of father: High blood pressure 0.3 0.4 1.0 0.2 -0.9 0.7 -1.0 0.8 0.2 0.4 0.5
Alcohol drinker status: Never 0.7 0.8 3.4 -0.3 -0.3 0.5 0.9 0.4 -1.2 -0.1 -1.8
Ever smoked 0.9 1.5 4.3 -0.4 -1.4 -0.5 -0.1 2.1 1.2 1.1 -1.7
Basal metabolic rate 0.4 2.3 7.6 0.1 0.4 1.5 -2.3 -1.1 -0.1 -1.4 2.8
Leg fat percentage (left) 1.8 6.4 20.6 2.3 -0.6 3.5 -2.9 -2.1 0.5 0.3 4.5
Arm fat-free mass (left) 0.6 3.0 8.9 0.3 0.6 1.4 -2.7 -1.6 -0.7 -1.5 3.0
Number of operations (self-reported) 0.7 1.1 3.4 1.8 -0.4 0.2 -0.5 0.9 0.7 1.8 -0.2
Average weekly beer plus cider intake 0.1 0.1 0.6 0.2 -0.2 0.3 -0.0 -0.2 0.8 0.4 0.4
Irritability 0.2 0.3 1.3 -1.1 0.6 -0.8 0.2 0.3 -0.4 -0.0 -0.3
Risk taking 2.2 3.2 10.8 1.4 -2.9 3.3 0.9 0.1 1.2 1.2 0.7
Ever had prostate specific antigen (PSA) test 0.2 0.3 1.4 0.3 0.0 0.1 -1.2 -0.1 0.3 0.6 0.4
Fractured/broken bones in last 5 years 0.3 0.4 1.5 -1.0 0.2 -0.5 -0.1 0.6 1.2 -0.4 0.1
Age started oral contraceptive pill 1.5 1.9 7.6 2.8 -0.6 -0.4 -2.2 0.5 0.4 1.3 0.2
Diastolic blood pressure, automated reading 0.4 1.3 3.0 -0.2 -0.9 1.5 -0.8 0.4 1.7 1.3 1.3
Ever depressed for a whole week 1.5 1.9 5.9 1.4 -1.5 1.3 -0.3 1.1 2.4 1.3 -0.5
Unable to work because of sickness or disability 0.5 0.6 1.3 0.7 -0.0 0.4 -1.2 -1.2 -0.9 -0.9 0.1
Commuting to job workplace: Cycle 0.3 0.4 1.3 0.4 -0.2 0.5 -0.6 -0.1 -0.2 -1.1 1.1
Myopia 0.7 1.1 4.6 2.1 -0.5 1.6 0.6 -0.1 0.5 0.6 0.6
Vascular/heart problems diagnosed by doctor 0.8 2.1 7.6 -0.0 -0.8 -0.4 1.5 2.0 0.5 1.2 -2.8
Cholesterol lowering medication 0.9 1.4 2.5 1.1 1.2 -0.1 -1.6 -0.6 -1.5 -1.5 0.9
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 0.5 -0.3 -0.7 0.7 -0.7 -0.2 0.7 0.2 0.1
Pain experienced in last month 1.1 1.9 6.6 -1.0 1.3 -2.6 0.7 0.7 -1.1 -1.2 -1.4
Supplements: Calcium 0.3 0.3 1.9 0.0 0.2 -1.4 0.1 -0.1 -0.3 0.1 -0.8
Basal cell carcinoma (self-reported) 0.3 0.4 0.9 0.4 -0.6 0.4 -0.9 0.7 0.8 0.2 -0.5
Heart attack/myocardial infarction (self-reported) 0.9 1.1 3.9 1.0 -2.0 1.9 0.1 -0.1 0.0 -0.1 0.4
Deep venous thrombosis (DVT) (self-reported) 1.4 1.8 5.0 1.0 -1.3 0.3 -1.6 2.2 0.3 0.9 -1.6
Heart disease (siblings) 1.0 1.3 4.0 -0.7 -0.4 1.8 1.2 -0.7 0.1 0.5 2.0
Alcohol drinker status: Previous 0.3 0.3 1.2 -0.7 0.1 -0.7 1.1 0.3 0.1 0.3 -0.6
Pack years of smoking 0.8 1.2 2.6 0.6 -1.5 0.5 0.8 1.1 1.6 1.3 -0.8
Impedance of whole body 0.7 3.4 9.2 0.3 -1.0 -0.8 2.9 1.9 0.1 2.0 -3.0
Leg fat mass (left) 1.5 5.8 22.4 1.6 -0.0 3.1 -2.7 -2.1 0.3 -0.5 4.7
Arm predicted mass (left) 0.5 2.6 7.8 0.3 0.6 1.3 -2.6 -1.3 -0.6 -1.4 2.8