Hub : Genes

MAN2A2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellum	0.2940	0.0880	0.00038	0.288	NA	0.220	NA	0.159	3.6e-09	NA	4.0e-07	NA	2.0e-05
2	GTEx	Muscle Skeletal	0.1503	0.0567	0.00250	0.008	NA	0.021	NA	0.027	5.0e-02	NA	3.5e-03	NA	1.1e-03
3	GTEx	Testis	0.2740	0.0920	0.00150	0.104	NA	0.039	NA	0.098	2.4e-05	NA	7.7e-03	NA	4.1e-05
4	METSIM	Adipose	0.0413	0.0167	0.00180	-0.001	0.013	-0.001	0.011	-0.002	6.0e-01	3.4e-03	4.5e-01	7.1e-03	7.7e-01
5	YFS	Blood	0.1626	0.0290	0.00000	0.061	0.095	0.118	0.111	0.127	2.3e-19	1.9e-29	1.3e-36	3.4e-34	1.9e-39
6	TCGA	Brain Lower Grade Glioma	0.0508	0.0291	0.00460	0.033	0.010	0.018	NA	0.024	1.1e-04	2.6e-02	3.0e-03	NA	8.2e-04
7	TCGA	Prostate Adenocarcinoma	0.0286	0.0164	0.00570	0.027	0.025	0.020	NA	0.021	7.7e-04	1.0e-03	3.0e-03	NA	2.7e-03
8	TCGA	Thyroid Carcinoma	0.0480	0.0260	0.00290	0.012	0.009	-0.001	NA	0.007	2.2e-02	4.2e-02	4.4e-01	NA	5.6e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.1	0.1	0.5	-0.2	-0.3	0.0	-0.2	-0.7	0.2	-0.1	-0.1
Bipolar Disorder or Schizophrenia	2.1	5.1	10.9	1.9	2.0	-2.7	0.8	-3.3	0.7	2.7	2.6
Depressed Affect (Nagel 2018)	0.8	1.7	3.5	-1.1	-1.3	1.5	-1.6	0.4	0.1	-1.9	-1.6
Depression (Nagel 2018)	1.2	1.8	4.7	-1.8	-0.8	1.6	-2.2	-0.5	1.1	-1.3	-0.4
Intelligence (Savage-Jansen 2018)	0.3	0.9	2.5	-0.1	-1.6	0.3	-0.0	1.4	-1.1	-1.3	-0.4
Neuroticism (Nagel 2018)	0.7	1.7	4.0	-0.6	-2.0	1.0	-1.6	0.4	-0.6	-1.6	-1.6
Schizophrenia (2018)	3.8	7.8	12.7	2.5	2.7	-3.5	1.3	-3.1	0.7	3.6	3.4
Schizophrenia vs Biploar Disorder	0.2	0.2	1.0	0.5	1.0	-0.3	0.1	0.1	-0.7	-0.1	-0.1
Worry (Nagel 2018)	1.2	2.6	4.7	-0.6	-2.0	1.0	-1.9	1.3	-1.2	-2.2	-1.9
Alzheimer’s Disease (in mother)	1.0	1.1	2.6	-1.1	-1.2	1.5	-1.6	0.2	0.4	-0.9	-0.6
Alzheimer’s Disease (in father)	1.3	1.4	4.6	-1.7	0.5	1.2	-1.2	-0.6	2.1	0.0	-0.2
Alzheimer’s Disease (including proxy)	1.7	2.4	5.5	-2.2	-1.0	1.9	-2.3	-0.4	2.0	-0.5	-0.4
Crohns Disease (2017)	0.3	0.6	1.5	0.5	-0.8	-0.0	-0.8	0.6	-1.2	-1.0	-0.4
Irritable Bowel Disease (IBD)	0.1	0.2	0.9	0.5	0.2	-0.3	0.6	0.9	-0.4	-0.1	0.3
Ulcerative Colitis (UC)	0.2	0.3	1.1	-0.1	0.8	-0.1	1.0	0.6	0.4	0.4	0.4
Major Depression (MDD)	0.3	0.4	1.7	-0.4	0.5	0.8	1.3	-0.0	0.0	0.0	0.0
Reaction Time	0.2	0.5	2.1	-0.3	0.2	-0.1	-1.4	-0.4	0.8	0.6	0.4
Verbal and Numeric Reasoning (VNR)	0.5	1.1	3.1	0.0	-0.6	0.5	0.4	1.8	-1.4	-1.6	-0.9
Breast Cancer	4.7	11.4	25.5	-3.3	-3.1	4.2	-1.6	2.1	-1.1	-5.1	-4.4
Ovarian Cancer	2.1	2.8	6.7	-1.1	-2.1	2.0	0.7	1.9	-0.4	-2.6	-1.5
Prostate Cancer	0.2	0.3	1.7	-0.1	-0.5	0.1	1.3	-0.1	0.7	-0.1	-0.3
Age at First Birth	1.5	2.1	4.3	2.1	1.7	-1.6	1.8	-0.2	-1.7	0.9	0.7
Bipolar Disorder (2011)	1.0	1.0	2.5	0.9	-0.0	-1.1	-1.0	-1.1	-0.4	1.1	1.6
Body Mass Index (BMI) (2010)	0.3	0.4	2.7	-0.1	1.6	-0.1	-0.3	0.3	0.6	-0.3	-0.1
Coronary Artery Disease (CAD)	1.1	1.3	2.9	-0.6	-0.1	0.1	-1.0	-1.3	1.4	1.5	1.7
Crohns Disease (2012)	0.9	1.4	4.4	0.6	-1.6	-0.0	-0.2	2.1	-1.2	-1.5	-0.3
Mean Putamen Volume	3.2	3.7	8.2	0.6	1.0	-1.5	1.9	-2.9	1.0	2.4	2.7
Fasting Glucose	2.3	2.8	7.3	-2.2	0.7	1.7	-2.7	0.3	0.9	-2.1	-1.2
HbA1C	0.6	0.7	4.5	0.2	2.1	-0.5	0.4	-0.1	0.1	0.2	0.7
HDL Cholesterol	0.4	0.6	1.8	0.7	-0.9	-0.1	1.2	0.6	-1.3	0.1	-0.4
LDL Cholesterol	1.1	1.7	3.5	1.8	1.9	-1.7	0.6	-0.2	-1.5	1.0	0.7
Lupus	0.9	1.3	3.5	-0.6	-0.5	0.2	-0.7	-1.9	1.4	1.1	1.6
Neuroticism (2016)	0.6	0.8	3.7	-0.8	-0.5	1.1	-1.9	-0.4	0.9	-0.4	0.0
Primary Biliary Cirrhosis	0.6	0.9	2.0	-0.3	-0.2	-0.6	-0.3	-1.4	1.3	1.1	1.3
Rheumatoid Arthritis	0.3	0.5	1.4	0.8	-1.1	-0.4	0.2	-0.0	-1.2	0.2	-0.2
Schizophrenia (2014)	1.7	3.7	7.1	1.9	2.1	-2.7	1.2	-2.3	0.0	1.9	2.0
Triglycerides	1.4	2.2	5.4	2.2	1.4	-2.3	0.6	-0.4	-1.4	0.8	1.6
Type 2 Diabetes (T2D) (2012)	4.0	4.6	13.0	-3.6	-1.4	2.9	-2.2	-0.5	2.2	-1.5	-1.0
Ulcerative Colitis	0.2	0.2	0.5	-0.5	0.5	0.5	0.5	0.4	0.7	0.3	0.4
Blood Eosinophil Count	0.7	5.2	15.6	-3.0	-1.2	2.4	-4.0	-0.9	3.0	-0.1	0.1
Blood Platelet Count	1.4	16.2	47.6	2.5	2.9	-3.8	2.1	-3.5	2.6	6.9	5.4
Blood Red Count	0.0	0.4	1.3	-0.1	-0.6	-0.1	1.1	1.1	-0.2	-0.1	0.6
Blood White Count	0.1	0.5	1.5	0.7	0.1	-0.5	0.2	0.7	0.4	1.2	1.2
Heel T-Score	0.6	4.5	8.4	-1.6	-2.6	2.5	-2.3	1.0	-0.7	-2.9	-2.2
BMI	0.2	1.0	2.8	-1.2	-0.8	-0.2	-0.2	-0.8	1.7	0.8	1.3
Height	0.2	3.2	6.1	2.4	1.4	-2.5	1.5	-0.6	-0.2	1.8	2.5
Waist Hip Ratio (WHR)	0.3	1.2	2.0	0.8	1.1	-1.3	-0.9	-1.2	0.2	1.3	1.4
Systolic Blood Pressure	2.0	9.8	30.2	2.7	-1.7	-0.7	2.9	5.5	-4.6	-2.5	-1.6
Smoking Status	1.0	2.4	10.9	-1.7	-0.8	0.9	-3.3	-1.3	1.5	0.6	0.5
Allergy or Eczema	1.4	3.7	27.3	-0.2	-0.8	0.5	-5.2	-0.2	0.5	0.6	0.7
Cardiovascular Disease	0.3	0.8	4.6	-0.1	-0.9	0.2	0.1	2.1	-0.9	-0.7	-0.0
Hypothyroidism (self reported)	0.9	2.1	5.0	-0.8	-1.0	1.6	-1.2	1.1	-1.2	-2.2	-1.9
Respiratory disease	1.8	4.0	9.4	-2.3	0.3	1.3	-2.8	-2.6	3.1	0.7	0.5
Type 2 Diabetes (T2D) (2018)	1.1	2.0	4.3	-2.1	-1.6	1.7	-1.9	0.0	1.1	-1.1	-0.2
Lung FEV1/FVC ratio	0.1	0.3	1.6	0.1	1.3	-0.6	0.5	-0.5	0.1	-0.2	-0.0
Lung FVC	0.0	0.2	1.1	0.1	-1.1	0.1	0.1	-0.3	-0.3	-0.3	0.3
Neuroticism	1.2	2.9	7.3	-1.5	-2.0	1.8	-2.7	0.1	0.3	-2.0	-1.7
Chronotype (morning person)	0.3	0.7	2.5	1.2	0.0	-0.6	0.8	0.5	-1.6	-0.1	-0.3
Hair Pigment	0.0	1.3	4.4	1.1	1.6	-2.1	-0.1	-0.7	0.4	1.4	0.3
Tanning	0.2	1.9	4.6	-2.1	-0.4	2.1	-1.8	-0.1	0.8	-1.4	-0.9
Hand grip strength (left)	0.2	0.4	1.1	-0.4	0.1	0.2	0.8	0.6	-0.5	-1.0	-0.9
Number of treatments/medications taken	2.5	4.5	10.1	-3.2	-3.1	2.8	-1.5	0.7	1.7	-1.6	-0.5
Average weekly spirits intake	1.3	1.6	3.8	1.3	0.4	-1.3	0.8	-2.0	-0.1	1.4	1.6
Sensitivity / hurt feelings	0.4	0.6	2.4	-0.8	-0.8	0.5	-0.0	-1.5	0.9	0.6	0.3
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.0	-1.0	0.8	0.1	-0.5	-1.1	1.4	-0.1	0.3
Hearing difficulty/problems: Yes	0.2	0.4	1.1	0.4	0.5	-0.4	0.0	0.4	0.6	1.0	1.0
Relative age of first facial hair	0.7	1.4	3.6	-0.4	1.0	-0.1	-1.2	-1.6	1.9	1.2	0.8
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.7	0.7	-0.8	-0.7	0.4	-0.3	-0.8	0.5	0.4
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.8	0.1	-0.2	-0.1	-0.6	-0.9	-0.2	0.1	0.6
Ever had hysterectomy (womb removed)	0.6	0.6	1.9	0.1	-0.9	0.3	0.8	-0.8	-1.4	-0.6	-0.8
Systolic blood pressure, automated reading	2.2	6.5	16.6	2.1	-2.7	-0.4	1.8	3.8	-4.1	-2.0	-1.2
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	3.6	-0.7	-1.9	1.1	-1.3	1.8	-1.2	-1.4	-1.6
Angina	1.4	1.8	4.7	-0.2	-2.2	0.7	-0.9	1.9	-1.3	-1.6	-0.8
Medication for hormone replacement therapy	1.0	1.1	1.9	-1.1	0.2	0.1	-0.9	-1.4	1.1	1.4	1.2
Vitamin and mineral supplements	0.7	0.9	2.3	1.5	1.5	-1.4	-0.1	0.2	-0.8	-0.1	0.3
Supplements: Zinc	1.1	1.2	2.5	-1.2	0.2	1.2	0.5	1.6	0.5	-0.9	-1.6
Medication: Co-codamol	0.3	0.4	1.3	-0.8	-0.0	0.4	1.1	0.4	0.7	-0.3	-0.1
Medication: Metformin	2.2	3.1	9.2	-1.8	-2.7	1.8	-3.0	-0.4	1.0	-0.9	-0.0
Diabetes (father)	3.8	4.8	8.7	-3.0	-1.5	2.8	-2.4	0.4	1.8	-2.5	-2.0
Diabetes (mother)	1.6	2.0	6.4	-2.5	-0.3	1.5	-1.8	-0.3	1.4	-1.1	-0.8
Severe depression (siblings)	1.6	1.8	3.8	-0.9	-1.4	1.4	-0.8	1.6	-0.5	-1.9	-1.5
Pack years adult smoking proportion	0.5	0.8	3.8	-1.0	0.6	0.5	-0.6	0.3	1.9	0.4	0.5
Impedance of leg (right)	0.6	3.0	11.2	2.1	0.2	-0.9	0.7	3.4	-2.5	-0.9	-0.5
Leg fat-free mass (left)	0.3	1.4	3.5	-0.9	-0.2	-0.4	-0.0	-1.6	1.9	1.2	1.7
Trunk fat percentage	0.3	1.1	3.2	-0.5	-1.0	-0.4	0.1	-0.7	1.7	1.0	1.8
Hand grip strength (right)	0.4	1.1	2.4	-1.3	0.0	1.4	0.5	0.4	-0.0	-1.5	-1.6
Townsend deprivation index at recruitment	1.2	1.6	5.2	-1.0	-0.4	-0.1	-2.0	-0.4	2.3	1.0	1.2
Current tobacco smoking	0.5	0.8	3.0	-0.8	-1.5	0.5	-1.7	-0.0	-0.1	0.3	0.5
Average weekly fortified wine intake	0.4	0.5	1.2	-0.7	-0.0	0.7	0.4	-1.1	1.1	-0.1	0.3
Maternal smoking around birth	0.7	1.0	2.6	-1.5	-0.0	1.6	-1.1	-0.5	1.0	-0.5	-0.7
Fed-up feelings	0.0	0.1	0.2	-0.1	-0.5	-0.2	-0.4	-0.0	0.3	0.0	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	1.6	-0.9	-0.4	0.1	-1.3	-0.6	1.1	0.1	0.7
Relative age voice broke	1.3	1.9	4.9	-0.0	2.1	-0.7	-0.0	-2.2	1.6	1.6	0.7
Taking other prescription medications	2.6	4.0	10.5	-2.5	-3.2	2.1	-2.6	0.4	1.1	-1.7	-0.3
Age when periods started (menarche)	0.2	0.5	1.5	0.7	1.2	-0.8	0.9	0.1	-0.7	0.4	0.1
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.4	-0.2	-0.6	0.1	-0.6	0.1	-0.4	-0.2	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	3.4	0.3	-1.3	0.8	-1.5	0.9	-1.8	-1.8	-1.5
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.9	0.0	0.1	-0.4	0.2	1.1	0.2	0.9	1.4
Qualifications: CSEs or equivalent	0.9	1.2	4.2	-0.7	0.3	0.4	-1.4	2.1	0.5	-1.1	-1.1
Serious illness, injury or assault to yourself	0.2	0.3	1.2	-0.1	0.0	0.1	1.1	-0.6	0.4	0.5	0.3
High blood pressure	0.7	1.9	6.2	0.4	-2.5	-0.1	-0.4	2.5	-1.4	-0.6	0.6
Hayfever, allergic rhinitis or eczema	1.5	3.3	22.8	-0.8	-0.5	0.9	-4.8	-0.6	1.2	0.2	0.4
Multivitamins +/- minerals	0.5	0.7	1.5	-1.0	-0.9	0.6	0.6	-1.2	0.7	0.9	0.4
Stomach or abdominal pain in last month	3.9	4.8	10.7	-3.3	-2.9	3.0	-2.2	0.4	1.9	-1.1	-0.7
Supplements: Glucosamine	1.2	1.6	3.9	-1.2	-2.0	1.9	0.5	0.7	-0.1	-1.4	-1.2
Diverticular disease/diverticulitis (self-reported)	2.0	2.3	8.0	-1.2	-1.9	1.9	-2.8	-0.7	0.1	-1.0	-0.8
Medication: Atenolol	1.3	1.6	8.5	1.0	-1.2	-0.2	0.2	2.9	-1.3	-0.8	0.0
Medication: Levothyroxine sodium	0.8	1.4	3.2	-0.3	-1.1	0.8	-0.0	1.7	-1.3	-1.8	-1.1
Sitting height	0.1	0.6	2.3	0.7	-0.7	-0.8	0.3	0.1	-0.1	0.6	1.5
Chronic bronchitis/emphysema (father)	0.6	0.7	2.1	-0.9	0.2	0.6	1.4	-0.2	1.0	-0.9	-0.7
High blood pressure (mother)	1.6	2.3	5.4	-0.6	-1.8	1.3	0.7	1.7	-1.7	-2.3	-1.2
Body mass index (BMI)	0.3	1.2	2.6	-1.5	-1.5	0.6	-0.3	-0.9	1.6	0.3	0.8
Impedance of leg (left)	0.6	2.7	10.1	2.0	0.6	-1.1	0.8	3.2	-2.2	-0.6	-0.3
Leg predicted mass (left)	0.3	1.4	3.6	-0.9	-0.2	-0.3	-0.0	-1.5	1.9	1.2	1.6
Trunk fat mass	0.3	1.3	3.9	-0.5	-1.0	-0.5	0.1	-0.8	1.8	1.1	2.0
Waist circumference	0.3	1.0	3.6	-0.5	-1.0	-0.3	0.4	-0.8	1.2	1.0	1.9
Number of incorrect matches in round	1.2	2.0	6.3	-1.3	0.2	-0.3	-1.3	-0.8	2.5	1.2	2.0
Past tobacco smoking	0.1	0.3	0.9	-0.2	0.2	0.1	0.9	0.8	0.1	-0.3	-0.6
Alcohol usually taken with meals	0.2	0.4	0.8	0.1	0.3	0.6	0.9	0.3	-0.7	-0.8	-0.7
Nervous feelings	0.6	1.0	2.1	0.7	-0.5	-0.2	0.3	1.4	-1.4	-1.1	-1.4
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	3.2	-1.8	0.9	1.4	-0.4	-0.2	1.5	-1.1	-1.2
Hearing difficulty/problems with background noise	0.2	0.4	1.4	-0.1	-1.2	0.7	-0.7	0.3	-0.1	-0.7	-0.5
Hair/balding pattern: Pattern 2	0.1	0.2	0.9	-0.0	1.0	0.3	-0.0	-0.2	0.5	0.2	-0.3
Had menopause	0.3	0.4	2.2	0.3	0.3	0.0	0.4	-0.1	-1.5	-0.7	-0.4
Had other major operations	1.1	1.4	3.5	-1.9	-0.1	1.6	-1.6	-0.4	1.4	-0.5	-0.2
Forced vital capacity (FVC)	0.1	0.3	0.8	-0.2	-0.3	0.4	-0.3	0.7	-0.3	-0.9	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	2.8	-0.1	-1.3	1.0	-1.3	0.7	-1.5	-1.7	-1.3
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.9	0.5	0.9	-1.0	-0.1	-0.3	-0.1	0.5	0.8
Qualifications: None of the above	0.2	0.4	1.0	-0.4	-1.0	0.7	0.8	-1.0	-0.1	-0.1	-0.3
Financial difficulties in last 2 years	1.6	2.1	6.0	-1.1	1.4	0.0	-2.4	-1.2	1.9	1.2	1.1
Mouth/teeth dental problems	0.5	0.8	3.2	0.1	0.1	-0.5	1.8	0.6	-0.5	-1.3	-0.6
Heart attack	0.4	0.6	3.1	0.3	-1.0	0.5	0.2	1.8	-0.2	-0.2	-0.1
Allergy	1.7	3.9	18.2	1.2	0.2	-0.8	4.3	0.9	-2.7	-0.9	-1.2
Pain all over the body in last month	0.9	1.0	2.5	-1.6	-0.7	0.7	-0.6	1.2	1.5	-0.2	0.3
Diabetes (self-reported)	1.5	2.2	5.9	-2.0	-1.6	1.8	-2.4	-0.1	1.0	-1.0	-0.2
Hayfever/allergic rhinitis (self-reported)	2.5	3.3	10.5	-2.3	-2.0	1.9	-3.2	-0.6	0.9	-0.9	-0.8
Medication: Ramipril	0.9	1.2	3.0	-1.3	-1.7	1.2	-1.0	0.0	0.3	-1.4	-0.3
Medication: Simvastatin	0.1	0.1	0.3	0.5	0.0	0.0	-0.3	-0.5	-0.5	0.4	0.2
Fluid intelligence score	0.4	0.9	2.8	-0.6	-0.5	1.0	-0.2	0.8	-0.9	-1.7	-1.0
Illnesses of siblings	0.9	1.2	2.3	-0.1	1.5	-0.9	-1.0	-1.0	1.3	1.4	0.9
Neuroticism score	0.2	0.5	1.2	-0.4	-1.1	0.4	-1.0	0.3	0.1	-0.8	-0.7
Weight	0.3	1.5	4.5	-0.6	-0.8	-0.6	0.2	-1.1	1.6	1.4	2.1
Impedance of arm (right)	0.1	0.3	1.0	0.5	1.0	-0.1	-0.8	-0.0	-0.2	-0.1	-0.3
Arm fat percentage (right)	0.5	1.9	5.0	-1.6	-1.3	0.7	-0.9	-1.6	2.2	0.6	1.1
Trunk fat-free mass	0.1	0.5	1.9	0.2	-0.3	-0.8	0.6	-0.4	0.3	0.9	1.4
Hip circumference	0.2	0.8	2.7	-0.6	-1.6	0.1	1.0	0.1	0.8	0.4	1.3
Time employed in main current job	0.6	0.7	1.9	0.8	-0.1	-0.8	0.2	-1.4	-0.3	1.1	1.1
Alcohol intake versus 10 years previously	0.4	0.6	2.1	-1.4	-0.2	0.8	-0.7	-0.3	0.5	-0.0	0.9
Father’s age at death	0.4	0.5	2.5	-0.6	-0.0	0.8	-0.6	-1.6	0.2	-0.6	-0.3
Worrier / anxious feelings	0.3	0.5	1.4	-0.5	1.1	0.2	-1.0	-0.5	1.2	-0.1	-0.2
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.7	5.1	-0.9	1.0	-0.7	-0.5	-1.0	2.3	1.4	1.8
Falls in the last year	2.4	3.3	9.3	-3.0	-1.2	2.6	-0.4	-0.5	2.5	-0.7	-1.3
Hair/balding pattern: Pattern 3	0.3	0.4	0.9	0.8	-0.7	-0.6	0.2	0.4	-0.9	0.2	0.5
Number of live births	0.5	0.7	2.0	-0.4	-1.4	1.1	-0.6	0.6	-0.5	-0.9	-0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.7	-0.2	0.3	0.4	0.2	1.0	-0.2	-1.3	-0.9
Pulse rate	0.2	0.4	1.7	-1.3	0.2	0.5	0.7	0.2	0.4	-0.3	-0.1
Happiness	0.4	0.5	1.9	-0.0	0.5	-0.8	-0.1	-0.1	0.6	0.8	1.4
Noisy workplace	1.0	1.2	2.8	1.4	1.5	-1.7	0.0	-0.3	-0.3	1.2	1.0
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.3	-0.1	-0.1	0.1	-1.2	-0.4	-0.0	-0.2	0.1
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.9	-1.3	-0.6	1.4	-2.0	-0.4	0.3	-1.2	-1.3
Mouth/teeth dental problems: Dentures	0.1	0.2	0.6	0.1	0.2	0.3	-0.7	-0.1	0.8	0.4	-0.2
Asthma	1.7	3.4	9.8	-1.4	0.2	0.6	-2.9	-1.7	3.1	1.5	1.3
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.6	0.1	-0.5	0.2	0.1	1.3	0.3	-0.9	-0.7
Medication: Cholesterol lowering	0.4	0.7	2.4	-1.2	-1.6	1.3	0.1	0.1	0.2	-0.4	0.1
Depression (self-reported)	2.0	2.4	6.2	-1.9	-0.5	0.9	-0.9	-2.5	2.3	0.9	1.2
Medication: Lansoprazole	0.6	0.7	2.5	-0.9	-1.6	0.7	-0.5	1.0	0.2	-0.4	-0.5
Prospective memory result	2.1	2.6	5.2	1.4	0.9	-2.3	2.1	-0.0	-0.1	2.1	2.0
Lung cancer (father)	0.4	0.5	1.1	-0.9	0.4	0.7	0.4	-1.0	1.0	0.5	-0.1
Illnesses of mother	2.0	2.4	5.4	1.6	1.9	-1.7	1.1	-1.7	0.6	2.3	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.5	1.6	-0.4	0.3	0.5	-0.1	0.5	-0.0	-1.2	-1.3
Pulse wave Arterial Stiffness index	0.5	0.6	1.5	1.0	0.8	-0.8	0.3	1.2	0.1	0.4	0.8
Impedance of arm (left)	0.1	0.3	1.3	0.7	1.1	-0.4	-0.5	-0.3	0.2	0.3	0.1
Arm fat mass (right)	0.3	1.2	3.1	-1.2	-1.4	0.3	-0.4	-1.1	1.8	0.5	1.1
Trunk predicted mass	0.1	0.4	1.7	0.2	-0.3	-0.7	0.6	-0.3	0.2	0.8	1.3
Standing height	0.3	3.0	6.3	2.1	1.2	-2.4	1.1	-0.3	-0.1	2.1	2.5
Length of working week for main job	0.2	0.2	0.6	-0.0	-0.2	0.1	0.7	0.8	0.3	0.4	0.5
Exposure to tobacco smoke at home	0.8	0.9	2.1	-0.9	-1.4	1.2	-0.6	0.7	-0.1	-1.3	-0.9
Breastfed as a baby	0.7	0.8	1.9	1.1	-0.9	-0.7	0.4	1.0	-1.0	0.2	1.4
Tense / ‘highly strung’	1.1	1.9	4.6	-1.9	-1.6	1.6	-2.1	-0.2	0.9	-1.0	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.1	7.6	-2.3	-0.9	1.4	-2.8	-1.8	2.4	0.2	0.6
Hair/balding pattern: Pattern 4	0.8	2.0	5.7	-0.6	-1.0	1.1	-2.4	0.9	-0.9	-1.6	-1.9
Birth weight of first child	4.2	7.6	18.3	0.0	4.3	-1.7	-1.2	-2.6	3.4	3.1	3.3
Peak expiratory flow (PEF)	0.5	1.1	3.4	-1.2	-0.5	1.1	0.1	1.1	0.3	-1.8	-1.2
Pulse wave reflection index	0.4	0.5	1.7	1.3	0.7	-0.5	-0.0	1.2	-0.5	-0.3	0.2
Ever highly irritable/argumentative for 2 days	1.2	1.4	3.9	-0.6	0.8	-0.3	0.5	-1.3	2.0	1.5	1.5
Loud music exposure frequency	0.4	0.4	1.1	-1.0	-0.1	0.8	0.8	-0.3	0.2	-0.2	-1.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.5	0.3	-0.7	0.0	-0.7	0.4	-0.5	-0.4	0.2
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.1	1.1	0.2	-1.0	-0.6	-0.3	-0.7	1.5	1.1
Blood clot in the leg (DVT)	0.3	0.3	1.3	0.0	0.7	0.2	0.2	-0.1	1.1	0.3	0.8
Medication: Paracetamol	0.4	0.7	3.4	0.3	-0.3	-0.1	-0.7	1.8	-0.4	-0.9	-0.8
Headache pain in last month	0.4	0.7	1.8	-1.2	-0.1	0.8	-1.3	-0.5	1.3	-0.0	-0.0
Medication for cholesterol, blood pressure or diabetes	1.0	1.7	6.1	1.0	2.5	-1.1	0.5	-1.8	0.2	1.4	0.0
Glaucoma (self-reported)	0.9	1.1	2.8	0.1	-1.7	0.1	-1.1	1.4	-1.1	-1.0	-0.5
Gout (self-reported)	0.8	1.0	2.5	1.5	0.7	-1.2	0.1	-1.6	-0.6	1.0	0.5
Hypothyroidism/myxoedema (self-reported)	1.2	2.3	5.7	-0.6	-0.6	1.3	-0.6	2.4	-1.2	-2.4	-1.8
Medication: Amlodipine	1.6	2.2	4.3	-0.9	-1.8	1.4	0.0	1.7	-1.1	-2.1	-1.8
Medication: Ventolin 100micrograms inhaler	1.7	2.2	7.9	-1.1	1.9	0.4	-1.0	-0.9	2.8	1.3	1.1
Birth weight	1.8	3.9	9.4	0.6	2.4	-1.5	-0.6	-3.1	1.8	2.3	2.1
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.7	-1.3	0.1	1.1	-0.8	-0.1	1.3	-0.8	-0.6
High blood pressure (siblings)	1.3	1.9	5.4	0.7	-2.3	0.1	1.8	1.5	-1.9	-0.9	-0.1
Forced vital capacity (FVC), Best measure	0.1	0.2	0.6	-0.5	-0.1	0.4	-0.4	-0.0	0.1	-0.6	-0.8
Body fat percentage	0.3	1.2	3.3	-0.9	-1.3	0.0	-0.3	-0.8	1.8	0.8	1.7
Leg fat percentage (right)	0.3	1.1	3.1	-1.3	-1.8	0.6	-0.7	-0.2	1.4	0.2	1.2
Arm fat-free mass (right)	0.2	0.8	3.0	0.1	-0.6	-0.8	1.0	-0.2	0.6	1.0	1.7
Exposure to tobacco smoke outside home	0.6	0.7	2.9	-0.2	-1.7	0.3	-1.0	0.3	-0.7	-1.1	-0.4
Comparative body size at age 10	0.3	0.9	3.3	-0.5	-1.6	0.5	0.0	-0.1	-0.6	-0.6	-1.8
Number of full brothers	0.7	0.8	3.2	-0.4	-1.6	0.1	-1.8	-0.2	0.3	-0.1	0.8
Worry too long after embarrassment	0.2	0.3	1.1	0.2	0.7	-0.2	0.4	-0.6	0.3	1.0	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	4.5	-1.1	0.2	0.0	-1.7	-2.1	1.9	1.3	1.8
Wheeze or whistling in the chest in last year	1.4	2.4	5.1	-2.2	-1.0	2.0	-2.1	-0.1	2.2	-0.3	-0.3
Number of children fathered	0.9	1.1	3.5	-1.0	-1.0	1.9	-0.1	-0.1	0.8	-0.9	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.8	1.0	-0.3	-0.4	0.3	1.5	-1.7	-1.0	-0.1
Age at first live birth	1.7	3.1	7.1	2.7	2.2	-2.1	1.2	1.1	-2.4	-0.1	-0.1
Pulse wave peak to peak time	0.4	0.4	1.8	-0.8	-0.7	0.5	-0.1	-1.3	-0.0	-0.2	-0.6
Health satisfaction	0.3	0.4	0.9	0.0	-0.5	-0.6	-0.8	-0.9	0.2	0.6	0.8
Shortness of breath walking on level ground	0.6	0.7	1.4	1.0	0.2	-1.2	0.9	1.0	-1.1	-0.0	0.2
Qualifications: College or University degree	0.2	0.6	3.3	-0.4	0.5	0.6	-0.7	-1.8	0.7	-0.0	-0.2
Eye problems/disorders: None of the above	0.4	0.5	2.1	0.0	1.4	-0.0	-0.4	-1.2	0.4	0.3	0.0
Mouth/teeth dental problems: Loose teeth	0.7	0.8	4.5	-0.4	-0.2	0.6	-2.1	-1.3	-0.1	0.0	-0.1
Emphysema/chronic bronchitis	0.8	0.9	2.1	-1.1	1.5	0.9	0.0	-0.9	1.4	0.1	-0.5
Medication for pain relief, constipation, heartburn	1.5	2.6	7.0	1.5	2.6	-1.5	2.0	-1.8	-0.8	1.2	0.0
Neck or shoulder pain in last month	1.2	1.7	7.4	-1.1	-2.7	1.0	0.0	1.1	-0.0	-1.0	-1.3
Medication: Blood pressure	1.0	1.8	5.7	-0.6	-2.4	0.7	0.3	2.2	-0.5	-1.6	-0.2
Angina (self-reported)	1.2	1.5	3.8	-0.1	-1.9	0.6	-0.8	1.7	-1.4	-1.5	-0.7
Migraine (self-reported)	0.3	0.3	0.7	-0.6	-0.9	0.6	-0.2	-0.4	0.3	0.6	0.6
Medication: Ibuprofen	0.5	0.6	1.8	-0.7	-0.9	0.8	-0.3	0.7	1.4	-0.8	-0.4
Medication: Allopurinol	0.4	0.6	3.3	0.1	0.4	-0.1	-0.4	-1.8	0.6	0.8	0.3
Medication: Omeprazole	2.6	3.1	9.6	-2.5	-3.1	2.1	-0.0	1.1	1.4	-1.3	-0.2
Medication: Seretide 50 evohaler	1.2	1.4	4.5	-0.9	1.4	-0.2	-1.1	-1.1	2.1	0.9	1.0
Mean time to correctly identify matches	0.4	0.8	1.5	-0.0	0.8	-0.3	-0.9	-1.0	0.7	1.2	1.2
Heart disease (mother)	0.4	0.5	1.4	-0.7	-1.2	0.6	-0.7	0.6	0.3	-0.4	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.7	-0.0	-1.3	0.7	-1.7	0.2	-0.2	-0.5	-0.3
Whole body fat mass	0.3	1.3	3.7	-0.8	-1.1	-0.2	0.1	-0.8	1.9	0.9	1.8
Leg fat mass (right)	0.3	1.1	2.9	-0.9	-1.2	-0.0	-0.2	-0.6	1.7	0.8	1.7
Arm predicted mass (right)	0.2	1.0	3.4	0.2	-0.2	-1.0	1.2	-0.2	0.6	1.1	1.9
Pulse rate, automated reading	0.1	0.2	0.4	0.3	-0.0	-0.6	0.4	-0.1	-0.6	0.5	0.6
Alcohol intake frequency.	0.6	1.4	5.5	-2.0	0.6	0.8	-0.8	-0.3	2.4	0.3	0.2
Comparative height size at age 10	0.2	1.4	2.9	1.1	0.6	-1.7	1.7	-0.5	-0.1	1.2	1.4
Number of full sisters	0.3	0.4	2.0	0.2	-1.4	0.1	0.1	-0.2	0.5	0.7	0.3
Suffer from ‘nerves’	1.9	3.0	6.2	-0.7	-2.4	1.6	-1.0	1.5	-0.9	-2.5	-2.2
Overall health rating	1.6	3.3	9.3	-3.0	-1.9	1.8	-2.4	-0.8	1.8	0.1	0.6
Chest pain or discomfort	0.8	1.2	2.5	-1.2	-1.4	1.4	-1.6	0.4	0.5	-1.0	-0.8
Had major operations	0.3	0.4	1.4	-1.2	-0.3	0.9	-0.2	-0.4	0.8	-0.2	0.1
Age at last live birth	0.2	0.3	0.9	0.0	0.5	0.0	-0.9	0.7	-0.3	-0.9	-0.3
Family relationship satisfaction	0.7	0.9	3.2	0.1	-0.4	-0.2	-0.6	-1.8	0.3	1.1	1.4
Leg pain on walking	0.5	0.7	1.4	0.4	1.2	-1.1	0.2	0.9	0.8	0.6	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	2.5	-0.8	1.5	0.6	-0.1	-0.6	1.6	1.0	0.1
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.1	1.1	0.4	-0.9	0.0	-1.4	-0.5	0.9	0.8
Illness, injury, bereavement, stress in last 2 years	1.1	1.4	2.8	1.5	-0.1	-1.7	1.1	-0.9	-0.4	1.5	1.3
Medication: Aspirin	2.4	3.2	11.9	-1.5	-3.4	2.1	-1.3	1.7	-0.3	-1.5	0.1
Supplements: Vitamin C	1.5	1.8	3.7	-1.6	-1.3	1.7	-1.9	0.8	0.7	-1.1	-1.2
Knee pain experienced in last month	0.4	0.7	2.0	-0.4	-0.6	-0.2	-0.0	-1.4	0.9	0.9	1.0
Hypertension (Self-reported)	0.6	1.5	5.5	0.2	-2.3	-0.1	-0.1	2.2	-1.2	-0.6	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	5.4	-1.0	-2.3	1.3	0.7	0.9	-0.3	-2.0	-0.9
Illnesses of father: Heart disease	0.9	1.3	4.9	-0.6	-0.7	1.1	-1.0	2.2	-0.2	-1.4	-0.5
Illnesses of siblings: Diabetes	5.0	6.2	14.0	-3.6	-2.0	3.7	-1.7	-0.5	1.0	-2.9	-2.5
Smoking status: Previous	0.1	0.2	1.1	-0.0	0.1	0.3	-0.2	-1.1	0.2	0.1	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	2.0	-1.1	0.3	0.3	0.1	0.7	1.4	-0.3	0.4
Whole body fat-free mass	0.1	0.7	2.3	-0.3	-0.3	-0.6	0.4	-0.8	0.9	1.1	1.5
Leg fat-free mass (right)	0.3	1.7	4.2	-0.9	0.1	-0.4	0.1	-1.8	2.1	1.4	1.7
Arm fat percentage (left)	0.4	1.7	5.3	-1.6	-1.3	0.7	-0.8	-1.4	2.3	0.5	1.0
Average weekly red wine intake	0.6	0.9	3.7	-0.9	-0.1	0.3	-1.9	-1.2	1.0	0.5	0.3
Handedness (chirality/laterality): Left-handed	2.0	2.3	5.4	-1.8	-0.9	1.9	-0.7	0.6	0.4	-2.2	-2.3
Mood swings	0.4	0.7	1.5	-0.5	-1.2	1.1	-1.1	-0.2	0.5	-0.6	-0.8
Loneliness, isolation	0.9	1.2	4.3	-1.2	-0.1	-0.1	-1.3	-0.8	2.1	0.6	1.1
Long-standing illness, disability or infirmity	0.9	1.3	3.5	-1.2	-1.9	0.9	-1.9	0.2	0.6	-0.6	0.5
Ever had bowel cancer screening	0.8	1.0	3.0	-0.7	-1.7	1.4	-1.0	-0.5	-0.5	-0.9	-0.1
Diabetes diagnosed by doctor	2.4	4.0	9.4	-2.3	-2.9	2.3	-3.1	0.7	0.6	-1.7	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	3.3	-1.7	-1.0	1.8	-1.4	-0.6	0.7	-1.1	-1.6
Friendships satisfaction	2.4	3.0	8.0	0.2	1.1	-1.6	0.7	-1.6	1.6	2.6	2.8
Qualifications: nursing, teaching	0.2	0.4	1.2	-0.4	0.2	0.3	0.6	1.1	-0.0	-1.0	-0.5
Commuting to job workplace: Walk	1.3	1.4	5.9	-1.4	0.3	0.4	-0.0	-0.7	2.4	1.2	1.1
Eye problems/disorders: Cataract	0.4	0.4	1.6	0.1	0.3	-0.3	0.8	0.2	0.6	0.8	1.3
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	5.7	-1.3	-0.7	1.6	-2.4	-0.7	1.1	-0.5	-0.2
Medication for cholesterol	0.2	0.3	1.3	-0.2	0.2	0.2	0.2	-0.2	0.5	-1.1	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.7	-0.5	0.1	0.1	0.4	-0.8	0.2	0.4	-0.5
Back pain experienced in last month	0.4	0.6	1.3	-1.1	-0.7	1.1	-0.3	0.2	0.9	-0.7	0.1
Mineral and other dietary supplements	2.4	3.2	9.6	1.6	3.1	-2.4	-0.3	-1.2	0.2	1.9	1.6
Breast cancer (self-reported)	0.7	0.8	1.8	0.1	1.3	-0.7	-1.0	-1.3	0.3	1.1	-0.2
Asthma (self-reported)	1.6	3.1	8.8	-1.3	0.0	0.7	-3.0	-1.8	2.8	1.3	1.0
Osteoporosis (self-reported)	4.5	5.6	16.2	-0.0	1.2	-1.3	-0.1	-2.4	2.8	3.3	4.0
Osteoarthritis (self-reported)	0.5	0.7	3.0	-0.8	-1.7	0.9	0.6	0.6	0.3	-0.6	-0.5
Medication: Aspirin	2.2	2.9	10.8	-1.5	-3.3	2.0	-1.1	1.3	-0.3	-1.6	-0.1
Medication: Gliclazide	2.8	3.1	7.0	-2.4	-1.9	2.2	-2.6	0.4	1.1	-1.3	-0.9
Illnesses of father: None of the above (group 1)	3.2	3.9	7.9	2.2	1.6	-2.8	1.6	-2.3	-1.0	2.3	1.5
Smoking status: Current	0.5	0.8	2.4	-0.8	-1.5	0.3	-1.3	-0.2	0.1	0.6	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.9	-0.4	0.5	0.1	-0.2	-1.4	0.6	0.3	0.6
Whole body water mass	0.2	0.9	2.7	-0.3	-0.2	-0.6	0.3	-1.0	1.1	1.2	1.7
Leg predicted mass (right)	0.3	1.7	4.3	-0.9	0.2	-0.4	0.1	-1.8	2.1	1.4	1.6
Arm fat mass (left)	0.3	1.3	3.6	-1.1	-1.3	0.1	-0.3	-1.2	1.9	0.7	1.4
Number of self-reported non-cancer illnesses	1.8	3.2	8.8	-2.6	-1.8	1.4	-1.6	0.1	3.0	0.2	1.5
Average weekly champagne plus white wine intake	0.2	0.3	0.5	0.3	0.5	-0.5	0.5	-0.7	0.5	0.7	0.6
Miserableness	0.5	0.9	1.9	-1.4	-0.6	1.1	-0.5	0.2	0.9	-1.2	-1.0
Guilty feelings	0.2	0.3	1.1	-0.2	-0.7	0.3	-1.0	-0.3	0.3	-0.1	-0.6
Wears glasses or contact lenses	0.4	0.5	1.8	-0.5	-0.2	0.5	-0.4	-1.4	1.0	0.3	0.4
Ever taken oral contraceptive pill	1.5	1.6	4.9	-0.2	0.9	-0.7	-0.3	-2.2	0.6	1.8	1.7
Hearing aid user	2.3	2.6	4.9	1.9	1.7	-2.2	2.1	1.3	-0.6	0.9	1.5
Mother’s age at death	3.1	3.9	9.1	-2.1	-1.1	2.7	-1.2	0.9	0.6	-3.0	-2.5
Financial situation satisfaction	0.4	0.4	1.3	-0.4	-0.2	-0.4	0.4	0.1	1.1	0.7	1.1
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.4	0.6	0.4	-0.8	-0.9	0.5	-0.5	0.0	1.2
Commuting to job workplace: Public transport	1.7	2.0	4.8	-2.2	-1.2	2.1	-0.6	-1.0	1.8	-0.8	-0.5
Eye problems/disorders: Glaucoma	1.1	1.3	4.0	-0.3	-2.0	0.4	-0.9	1.8	-0.7	-1.1	-0.6
Medication: Blood pressure	0.5	0.9	2.4	1.1	-0.7	-0.6	1.4	0.5	-1.6	0.5	0.5
Pain type(s) experienced in last month: Hip pain	0.6	0.7	1.6	-0.8	-0.9	0.3	-1.0	-1.3	0.6	0.8	0.6
Supplements: Fish oil (including cod liver oil)	1.4	1.8	5.7	-1.4	-2.4	1.8	-0.0	1.1	-0.2	-1.1	-1.1
High cholesterol (Self-reported)	0.4	0.7	2.5	-0.2	0.6	0.2	1.6	-1.2	0.4	0.6	0.6
Medication: Bendroflumethiazide	1.1	1.6	8.1	-0.1	-0.7	-0.5	2.8	2.0	-0.1	-0.1	0.3
Medication: Paracetamol	0.2	0.3	1.5	0.3	-0.1	-0.4	-0.6	1.2	0.1	-0.3	-0.2
Medication: Lisinopril	0.5	0.7	1.8	-0.1	1.2	-0.2	-0.3	-0.5	1.3	0.8	1.0
Medication: Atorvastatin	0.5	0.6	3.1	-0.3	-0.1	0.3	1.8	1.2	-0.3	-0.4	0.1
Illnesses of father: High blood pressure	4.1	5.1	9.5	-0.7	-3.1	2.0	-0.8	2.5	-2.0	-2.9	-2.7
Alcohol drinker status: Never	1.6	1.9	7.1	-1.7	0.4	0.8	-1.4	-1.2	2.7	0.9	0.5
Ever smoked	0.5	0.9	2.4	1.5	-0.2	-1.2	-0.6	0.6	-1.5	0.2	0.7
Basal metabolic rate	0.2	0.9	3.2	-0.2	-0.3	-0.8	0.4	-0.9	1.1	1.2	1.8
Leg fat percentage (left)	0.3	1.2	2.7	-1.4	-1.5	0.6	-0.8	-0.3	1.6	0.3	1.2
Arm fat-free mass (left)	0.1	0.6	2.6	0.2	-0.5	-0.8	0.6	-0.1	0.3	0.8	1.6
Number of operations (self-reported)	0.9	1.4	4.2	-2.0	-1.0	1.2	-0.3	-0.4	1.8	-0.0	0.9
Average weekly beer plus cider intake	0.2	0.3	0.6	0.8	0.0	-0.7	0.5	-0.2	-0.5	0.6	0.3
Irritability	0.1	0.2	1.1	0.3	-1.0	-0.1	0.3	-0.3	-0.0	0.2	-0.1
Risk taking	0.7	1.0	2.0	0.4	1.4	-0.7	-0.7	-1.2	1.0	1.1	1.2
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.6	0.4	-0.9	-0.1	1.6	0.3	-0.1	0.3	0.5
Fractured/broken bones in last 5 years	1.4	1.8	3.8	-1.5	-0.6	1.1	-0.7	-1.9	1.6	1.3	1.1
Age started oral contraceptive pill	1.1	1.4	3.5	1.9	0.2	-1.1	1.0	-0.1	-1.5	0.8	1.5
Diastolic blood pressure, automated reading	2.4	7.5	17.2	1.4	-3.6	0.0	1.1	4.0	-4.2	-3.0	-1.5
Ever depressed for a whole week	0.2	0.3	1.1	-1.1	-0.5	0.4	0.4	0.3	0.6	0.1	0.3
Unable to work because of sickness or disability	3.1	4.0	10.1	-3.2	-2.2	2.6	-1.4	-1.0	2.2	-1.1	-1.0
Commuting to job workplace: Cycle	0.3	0.3	1.0	0.4	1.0	-0.4	-1.0	-0.1	0.1	0.4	0.3
Myopia	1.2	1.7	3.1	1.8	1.6	-1.6	0.2	-0.8	-1.1	1.3	1.2
Vascular/heart problems diagnosed by doctor	0.8	2.3	8.4	-0.5	2.4	0.0	0.2	-2.9	1.7	0.8	-0.3
Cholesterol lowering medication	0.3	0.4	0.9	-0.5	0.9	0.6	0.3	-0.6	1.0	0.5	-0.0
Medication: Omeprazole (e.g. Zanprol)	2.2	2.7	8.2	-2.4	-2.9	2.0	-0.3	0.4	1.5	-0.8	0.2
Pain experienced in last month	2.4	4.0	10.0	3.2	3.1	-2.4	0.1	-0.6	-2.2	1.2	0.8
Supplements: Calcium	0.4	0.5	1.7	-0.6	-0.3	1.1	1.3	-0.1	0.7	-0.2	-0.2
Basal cell carcinoma (self-reported)	0.8	0.9	1.9	-1.1	-0.6	1.4	-0.2	0.7	-0.0	-1.2	-1.4
Heart attack/myocardial infarction (self-reported)	0.5	0.6	3.1	-0.0	-0.8	0.7	0.2	1.8	0.0	-0.5	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.7	0.0	0.7	0.2	0.1	-0.3	1.3	0.4	0.8
Heart disease (siblings)	0.8	1.0	2.8	1.2	-1.3	-0.0	0.6	1.7	-1.2	-0.6	-0.0
Alcohol drinker status: Previous	0.3	0.4	1.5	0.3	1.2	-0.6	-0.8	-0.4	0.3	0.3	-0.2
Pack years of smoking	0.6	0.9	4.2	-0.7	0.6	0.2	-0.3	-0.1	2.0	0.9	1.0
Impedance of whole body	0.2	0.9	2.8	1.4	0.8	-0.7	0.1	1.7	-1.1	-0.4	-0.3
Leg fat mass (left)	0.3	1.2	3.3	-1.0	-1.0	-0.1	-0.2	-0.7	1.8	0.9	1.7
Arm predicted mass (left)	0.1	0.5	2.2	-0.2	-0.7	-0.6	0.7	-0.2	0.6	0.7	1.5