TWAS hub - MAP3K8

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0537	0.0178	1.4e-04	0.030	0.024	0.043	0.027	0.042	1.9e-05	1.3e-04	3.7e-07	5.6e-05	5.4e-07
2	YFS	Blood	0.0804	0.0205	4.3e-08	0.015	0.039	0.045	0.045	0.034	5.4e-06	6.9e-13	1.2e-14	1.6e-14	2.1e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Crohns Disease (2017)	8.0	17.6	30.1	2.3	-5.5
Medication: Omeprazole (e.g. Zanprol)	6.8	8.3	9.1	3.0	2.8
Irritable Bowel Disease (IBD)	6.7	16.0	20.4	3.4	-4.5
Osteoarthritis (self-reported)	5.4	7.1	7.3	2.6	2.7
Crohns Disease (2012)	5.1	8.3	10.9	2.4	-3.3
Primary Biliary Cirrhosis	4.1	5.8	8.6	1.7	-2.9
Medication: Omeprazole	4.1	4.9	5.2	2.2	2.3
Medication: Seretide 50 evohaler	3.7	4.3	8.5	2.9	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.3	3.9	6.9	2.6	0.9
Age at First Birth	2.9	4.3	7.2	-2.7	-1.2
Ulcerative Colitis (UC)	2.8	5.2	6.6	2.6	-1.9
Medication: Paracetamol	2.7	4.4	7.0	1.4	2.6
Hayfever, allergic rhinitis or eczema	2.6	5.7	11.0	3.3	0.7
Medication: Cholesterol lowering	2.5	3.9	7.1	0.8	-2.7
Fractured/broken bones in last 5 years	2.5	3.2	5.6	2.4	-0.9
Financial difficulties in last 2 years	2.4	3.2	5.4	-1.0	-2.3
Chronic bronchitis/emphysema (father)	2.3	2.6	4.3	2.1	-1.0
Medication for cholesterol, blood pressure or diabetes	2.3	3.8	7.2	-0.6	2.7
Medication: Blood pressure	2.3	4.1	7.0	1.1	-2.6
Ulcerative Colitis	2.2	3.2	6.3	2.5	-0.3
Medication: Simvastatin	2.2	3.2	6.2	0.4	-2.5
Exposure to tobacco smoke outside home	2.0	2.7	4.6	0.9	-2.2
Allergy	1.9	4.3	7.7	-2.8	-0.9
Peak expiratory flow (PEF)	1.9	4.3	8.4	-2.9	-0.5
Shortness of breath walking on level ground	1.9	2.2	4.5	2.1	-0.0
Osteoporosis (self-reported)	1.9	2.4	4.6	2.1	0.5
Medication: Paracetamol	1.9	2.9	4.5	1.1	2.1
High cholesterol (Self-reported)	1.8	3.2	6.2	0.5	-2.5
Waist Hip Ratio (WHR)	1.7	7.4	14.7	0.5	-3.8
Allergy or Eczema	1.6	4.2	8.4	2.9	-0.1
Hayfever/allergic rhinitis (self-reported)	1.6	2.2	4.1	2.0	0.5
Commuting to job workplace: Public transport	1.6	2.0	3.7	1.9	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.5	5.5	1.2	2.3
Medication: Levothyroxine sodium	1.5	2.6	5.2	0.2	-2.3
Alcohol usually taken with meals	1.5	2.5	4.6	-0.6	2.1
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	2.7	-1.6	1.0
Alzheimer’s Disease (including proxy)	1.4	2.0	4.0	0.2	-2.0
Average weekly spirits intake	1.4	1.8	2.0	-1.3	1.4
Supplements: Glucosamine	1.4	1.9	3.6	-0.4	1.9
Worrier / anxious feelings	1.4	2.7	4.8	-2.2	-0.8
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.7	3.4	0.3	1.8
Number of self-reported non-cancer illnesses	1.4	2.5	2.8	1.7	-1.5
Bipolar Disorder (2011)	1.3	1.3	2.5	-0.2	1.6
Serious illness, injury or assault to yourself	1.3	1.6	3.1	1.8	-0.3
Had other major operations	1.3	1.6	3.2	-0.0	1.8
Heel bone mineral density (BMD) T-score, automated (right)	1.3	2.9	4.9	0.9	2.2
Pain all over the body in last month	1.3	1.4	2.0	-0.9	1.4
Asthma	1.3	2.5	4.2	2.0	0.9
Ever had bowel cancer screening	1.3	1.5	2.1	0.9	-1.5
Commuting to job workplace: Walk	1.3	1.4	1.9	1.0	-1.4
Medication: Lisinopril	1.3	1.6	3.2	0.1	-1.8
Medication: Atorvastatin	1.3	1.6	3.2	0.3	-1.8
Illnesses of father: High blood pressure	1.3	1.5	1.8	-1.1	1.4
Alzheimer’s Disease (in mother)	1.2	1.4	2.6	-0.5	-1.6
Coronary Artery Disease (CAD)	1.2	1.5	2.9	1.7	0.2
Ever had hysterectomy (womb removed)	1.2	1.3	2.4	1.6	-0.4
Multivitamins +/- minerals	1.2	1.6	3.1	0.3	1.8
Medication: Atenolol	1.2	1.5	2.0	-1.4	-1.1
Hearing difficulty/problems with background noise	1.2	1.9	3.4	1.9	-0.6
Prospective memory result	1.2	1.4	2.7	-1.6	-0.4
Hair/balding pattern: Pattern 4	1.2	2.9	3.1	1.6	-1.8
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	2.9	-1.7	-0.1
Health satisfaction	1.2	1.6	2.3	1.5	0.9
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	2.4	-1.5	0.7
Asthma (self-reported)	1.2	2.5	3.9	2.0	1.0
Tinnitus: Yes, now most or all of the time	1.2	1.4	1.8	-1.0	-1.4
Maternal smoking around birth	1.1	1.6	2.8	1.7	-0.7
Hair/balding pattern: Pattern 3	1.1	1.7	3.0	1.7	0.6
Glaucoma (self-reported)	1.1	1.3	2.5	0.3	-1.6
Hypothyroidism/myxoedema (self-reported)	1.1	2.1	4.0	-0.3	-2.0
Knee pain experienced in last month	1.1	1.7	2.4	1.0	-1.5
Supplements: Fish oil (including cod liver oil)	1.1	1.5	2.7	0.6	1.6
LDL Cholesterol	1.0	1.5	2.5	1.6	0.7
Medication: Ramipril	1.0	1.2	2.0	0.7	-1.4
Medication: Lansoprazole	1.0	1.2	2.2	1.5	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	1.3	1.1	1.1
Friendships satisfaction	1.0	1.2	2.5	-1.6	0.1
Alcohol drinker status: Never	1.0	1.2	1.9	0.7	-1.4
Schizophrenia vs Biploar Disorder	0.9	1.1	1.2	1.1	-1.0
Worry (Nagel 2018)	0.9	2.0	2.2	-1.3	1.5
Breast Cancer	0.9	2.1	3.9	0.5	2.0
Medication: Metformin	0.9	1.2	2.0	-0.6	-1.4
Relative age voice broke	0.9	1.4	2.6	1.6	0.4
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	1.1	0.9	1.0
Mouth/teeth dental problems	0.9	1.4	2.6	-1.6	-0.5
Birth weight of first child	0.9	1.6	2.1	1.4	-1.1
Loud music exposure frequency	0.9	1.0	2.0	1.4	0.0
Chronic bronchitis/emphysema (mother)	0.9	1.0	2.0	1.4	-0.1
Number of full brothers	0.9	1.2	1.4	1.0	1.2
Medication: Ibuprofen	0.9	1.0	2.1	-0.0	1.4
Number of operations (self-reported)	0.9	1.3	2.5	1.6	0.4
Irritability	0.9	1.5	2.7	-1.6	0.5
Alzheimer’s Disease (in father)	0.8	0.8	1.6	0.1	-1.3
Respiratory disease	0.8	1.7	3.3	1.8	0.3
Number of treatments/medications taken	0.8	1.4	2.8	1.7	-0.1
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.7	0.1	-1.3
Taking other prescription medications	0.8	1.3	2.4	1.6	0.4
Age at first live birth	0.8	1.5	2.3	-1.5	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	2.4	1.6	0.1
Back pain experienced in last month	0.8	1.1	1.6	0.8	1.3
Guilty feelings	0.8	1.2	1.6	-1.3	0.9
Heart disease (siblings)	0.8	1.0	1.9	1.4	0.2
Depression (Nagel 2018)	0.7	1.0	1.3	1.1	-0.8
Reaction Time	0.7	1.3	1.5	-1.0	1.2
HbA1C	0.7	0.8	1.4	0.4	1.2
HDL Cholesterol	0.7	1.2	2.4	1.5	-0.3
Cardiovascular Disease	0.7	2.3	3.9	0.9	-2.0
Type 2 Diabetes (T2D) (2018)	0.7	1.3	2.6	-0.0	-1.6
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.0	0.9	-1.0
Heart attack	0.7	0.9	1.2	0.8	-1.1
Diabetes (self-reported)	0.7	1.1	2.3	0.1	-1.5
Alcohol intake versus 10 years previously	0.7	1.0	1.5	-1.2	-0.8
Illnesses of mother	0.7	0.9	1.7	1.3	-0.0
Pulse wave Arterial Stiffness index	0.7	0.9	1.7	-0.2	-1.3
Breastfed as a baby	0.7	0.9	1.8	1.3	0.0
Tense / ‘highly strung’	0.7	1.1	2.2	-0.1	1.5
Headache pain in last month	0.7	1.2	1.9	-0.7	1.4
Pulse wave peak to peak time	0.7	0.8	1.6	0.1	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	1.5	-1.2	-1.2
Vascular/heart problems diagnosed by doctor	0.7	1.9	2.2	-1.2	1.5
Supplements: Calcium	0.7	0.8	1.5	-0.2	-1.2
Heart attack/myocardial infarction (self-reported)	0.7	0.9	1.3	0.8	-1.1
Prostate Cancer	0.6	0.9	1.0	1.0	-0.9
Fasting Glucose	0.6	0.7	1.4	0.1	-1.2
Hypothyroidism (self reported)	0.6	1.3	2.1	-0.7	-1.5
Sensitivity / hurt feelings	0.6	1.0	1.9	0.2	-1.4
Systolic blood pressure, automated reading	0.6	1.6	2.3	1.5	0.9
Diabetes (mother)	0.6	0.7	0.8	-0.8	0.9
Falls in the last year	0.6	0.8	1.5	1.2	0.4
Number of live births	0.6	0.8	1.3	-1.1	0.6
Happiness	0.6	0.8	0.8	-0.9	0.8
Exposure to tobacco smoke at home	0.6	0.7	1.3	-0.3	-1.1
Medication: Amlodipine	0.6	0.9	1.8	0.2	-1.3
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.5	1.2	0.1
Wheeze or whistling in the chest in last year	0.6	1.1	1.6	0.7	1.3
Number of children fathered	0.6	0.7	1.3	-1.1	-0.3
Medication for pain relief, constipation, heartburn	0.6	1.1	1.3	-0.9	-1.1
Hypertension (Self-reported)	0.6	1.6	1.8	1.3	-1.2
Mineral and other dietary supplements	0.6	0.8	1.4	0.3	-1.2
Medication: Aspirin	0.6	0.8	1.6	0.2	-1.3
Average weekly champagne plus white wine intake	0.6	0.8	0.9	1.0	-0.8
Ever taken oral contraceptive pill	0.6	0.6	1.2	-1.1	-0.1
Alcohol drinker status: Previous	0.6	0.7	0.8	0.7	-0.9
Rheumatoid Arthritis	0.5	0.6	1.3	-0.1	-1.1
Triglycerides	0.5	0.8	1.5	1.2	-0.3
Heel T-Score	0.5	3.8	7.0	-0.7	2.6
Fed-up feelings	0.5	1.0	1.4	-1.2	-0.7
Qualifications: CSEs or equivalent	0.5	0.7	1.3	-1.1	-0.1
High blood pressure	0.5	1.5	1.5	1.2	-1.2
Number of incorrect matches in round	0.5	0.9	1.4	-1.2	0.6
Nervous feelings	0.5	1.0	2.0	-1.4	0.0
Birth weight	0.5	1.0	1.4	1.2	-0.8
High blood pressure (siblings)	0.5	0.7	1.3	-1.1	0.3
Eye problems/disorders: None of the above	0.5	0.6	1.0	1.0	-0.3
Neck or shoulder pain in last month	0.5	0.7	0.8	-0.9	0.7
Long-standing illness, disability or infirmity	0.5	0.8	1.1	0.7	1.1
Breast cancer (self-reported)	0.5	0.6	1.1	1.0	0.3
Wears glasses or contact lenses	0.5	0.6	1.1	0.2	1.1
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.2	0.1	1.1
Pain experienced in last month	0.5	0.8	1.3	0.4	-1.1
Bipolar Disorder (2018)	0.4	0.6	1.0	0.4	1.0
Mean Putamen Volume	0.4	0.5	0.8	-0.5	-0.9
Blood Red Count	0.4	4.2	8.0	-2.8	-0.6
Lung FVC	0.4	1.9	2.3	-1.2	-1.5
Medication: Co-codamol	0.4	0.5	0.6	-0.8	-0.6
Townsend deprivation index at recruitment	0.4	0.5	0.7	0.6	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	0.8	0.5	-0.9
Impedance of leg (left)	0.4	2.0	3.4	-1.9	0.8
Had menopause	0.4	0.5	1.0	1.0	0.0
Forced vital capacity (FVC)	0.4	1.4	2.9	-0.2	-1.7
Qualifications: None of the above	0.4	0.8	1.5	-0.4	1.2
Illnesses of siblings	0.4	0.5	1.0	-0.3	-1.0
Time employed in main current job	0.4	0.5	0.9	-0.9	-0.3
Father’s age at death	0.4	0.6	0.8	-0.9	-0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.8	1.3	-0.1
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	0.9	0.5	-0.9
Forced vital capacity (FVC), Best measure	0.4	1.3	2.1	0.7	-1.4
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.0	-0.2	1.0
Suffer from ‘nerves’	0.4	0.6	0.8	-0.7	0.9
Leg pain on walking	0.4	0.5	1.1	1.0	0.2
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.8	-0.5	0.9
Arm fat percentage (left)	0.4	1.5	2.2	1.5	1.0
Qualifications: nursing, teaching	0.4	0.6	1.1	0.4	1.1
Medication: Gliclazide	0.4	0.4	0.5	0.6	-0.7
Eye problems/disorders: Glaucoma	0.4	0.4	0.6	0.5	-0.8
Myopia	0.4	0.6	1.1	-1.0	0.2
Schizophrenia (2018)	0.3	0.6	0.7	-0.7	-0.9
Blood Eosinophil Count	0.3	2.3	3.6	1.9	1.0
Systolic Blood Pressure	0.3	1.5	2.6	0.7	-1.6
Hearing difficulty/problems: Yes	0.3	0.4	0.8	-0.3	-0.9
Severe depression (siblings)	0.3	0.3	0.4	0.5	-0.6
Trunk fat percentage	0.3	1.3	1.8	1.3	0.8
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.6	-0.2	0.8
Hip circumference	0.3	1.5	2.0	1.0	1.4
Pulse rate	0.3	0.5	0.9	0.9	-0.4
Depression (self-reported)	0.3	0.4	0.7	-0.4	0.8
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.6	-0.4	-0.8
Body fat percentage	0.3	1.3	1.7	1.3	0.9
Leg fat percentage (right)	0.3	1.1	1.4	1.2	0.9
Qualifications: College or University degree	0.3	0.8	1.0	1.0	-0.8
Medication: Allopurinol	0.3	0.4	0.8	0.1	-0.9
Heart disease (mother)	0.3	0.4	0.6	0.4	0.8
Chest pain or discomfort	0.3	0.4	0.7	-0.9	-0.3
Had major operations	0.3	0.3	0.5	0.4	0.7
Age at last live birth	0.3	0.5	0.9	-0.9	0.2
Supplements: Vitamin C	0.3	0.4	0.7	0.1	-0.8
Illnesses of father: Heart disease	0.3	0.4	0.6	-0.8	0.4
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.4	0.7	-0.6
Diabetes diagnosed by doctor	0.3	0.6	1.0	-0.4	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.4	-0.7	0.5
Arm fat mass (left)	0.3	1.1	1.6	1.3	0.7
Ever smoked	0.3	0.5	1.0	-0.2	-1.0
Leg fat percentage (left)	0.3	1.2	1.8	0.8	1.3
Pack years of smoking	0.3	0.4	0.7	0.0	-0.9
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.0	0.5	-1.0
Neuroticism (2016)	0.2	0.3	0.4	-0.5	-0.7
Schizophrenia (2014)	0.2	0.3	0.5	-0.7	-0.4
Blood Platelet Count	0.2	2.8	5.2	0.6	2.3
Lung FEV1/FVC ratio	0.2	1.1	1.5	-1.2	0.8
Neuroticism	0.2	0.6	1.1	0.2	1.0
Hand grip strength (left)	0.2	0.5	1.0	-0.2	-1.0
Relative age of first facial hair	0.2	0.4	0.8	0.9	-0.1
Medication for hormone replacement therapy	0.2	0.3	0.5	0.7	-0.2
Pack years adult smoking proportion	0.2	0.3	0.5	-0.2	-0.7
Leg fat-free mass (left)	0.2	0.9	1.3	0.7	-1.1
Current tobacco smoking	0.2	0.3	0.3	-0.6	-0.5
Sitting height	0.2	1.5	3.0	-1.7	0.2
High blood pressure (mother)	0.2	0.3	0.4	-0.6	-0.5
Body mass index (BMI)	0.2	1.0	1.6	1.2	0.7
Leg predicted mass (left)	0.2	1.0	1.3	0.8	-1.1
Trunk fat mass	0.2	0.9	1.4	1.2	0.6
Waist circumference	0.2	0.7	0.8	0.9	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	0.7	-0.3	0.8
Hair/balding pattern: Pattern 2	0.2	0.2	0.4	-0.6	0.2
Arm fat percentage (right)	0.2	0.9	1.7	1.3	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.7	-0.8	-0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.4	-0.3	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	0.0	0.6
Mouth/teeth dental problems: Dentures	0.2	0.4	0.8	0.9	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	1.0	0.0	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.4	-0.4	0.6
Gout (self-reported)	0.2	0.2	0.3	0.5	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.5	-0.7	-0.4
Whole body fat mass	0.2	1.0	1.8	1.3	0.5
Overall health rating	0.2	0.3	0.4	0.6	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.9	-0.9	0.1
Average weekly red wine intake	0.2	0.3	0.4	0.4	0.6
Loneliness, isolation	0.2	0.3	0.3	0.5	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.5	0.0	0.7
Smoking status: Current	0.2	0.3	0.4	-0.6	-0.4
Miserableness	0.2	0.4	0.7	-0.8	0.2
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.5	0.7	-0.0
Average weekly beer plus cider intake	0.2	0.3	0.4	0.4	-0.6
Age started oral contraceptive pill	0.2	0.2	0.4	0.0	-0.6
Commuting to job workplace: Cycle	0.2	0.3	0.5	0.1	-0.7
Basal cell carcinoma (self-reported)	0.2	0.3	0.6	-0.7	-0.2
Neuroticism (Nagel 2018)	0.1	0.3	0.4	-0.6	0.4
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.4	0.6	-0.4
Ovarian Cancer	0.1	0.2	0.3	0.6	0.0
Body Mass Index (BMI) (2010)	0.1	0.2	0.3	-0.6	0.3
Lupus	0.1	0.2	0.4	-0.6	-0.2
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.2	0.4	-0.0
Blood White Count	0.1	0.4	0.4	0.6	0.7
Height	0.1	1.3	2.5	0.4	-1.6
Smoking Status	0.1	0.2	0.4	-0.3	0.6
Chronotype (morning person)	0.1	0.2	0.3	-0.6	0.1
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.2	-0.5	-0.4
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.1	0.3	-0.3
Angina	0.1	0.1	0.2	-0.3	-0.4
Vitamin and mineral supplements	0.1	0.1	0.1	-0.4	0.3
Supplements: Zinc	0.1	0.1	0.1	-0.2	0.3
Diabetes (father)	0.1	0.2	0.2	-0.5	-0.3
Impedance of leg (right)	0.1	0.5	1.0	-1.0	0.1
Hand grip strength (right)	0.1	0.3	0.4	0.5	-0.6
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.3	0.5	-0.2
Past tobacco smoking	0.1	0.2	0.2	0.4	0.5
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.1	-0.1	-0.4
Fluid intelligence score	0.1	0.3	0.6	0.8	0.0
Neuroticism score	0.1	0.2	0.4	-0.6	-0.0
Weight	0.1	0.5	1.1	1.0	0.0
Impedance of arm (right)	0.1	0.5	1.0	-0.1	-1.0
Trunk fat-free mass	0.1	0.4	0.7	-0.3	-0.9
Lung cancer (father)	0.1	0.2	0.3	0.2	0.6
Arm fat mass (right)	0.1	0.6	0.9	0.9	0.5
Trunk predicted mass	0.1	0.4	0.7	-0.3	-0.8
Standing height	0.1	0.7	1.3	-0.4	-1.1
Blood clot in the leg (DVT)	0.1	0.1	0.3	0.5	0.1
Emphysema/chronic bronchitis	0.1	0.1	0.2	0.1	-0.5
Angina (self-reported)	0.1	0.1	0.3	0.0	-0.5
Migraine (self-reported)	0.1	0.2	0.3	-0.3	0.6
Mean time to correctly identify matches	0.1	0.2	0.4	0.1	0.6
Leg fat mass (right)	0.1	0.4	0.6	0.8	0.5
Number of full sisters	0.1	0.1	0.2	-0.4	0.0
Family relationship satisfaction	0.1	0.1	0.1	-0.2	0.3
Medication: Aspirin	0.1	0.2	0.4	-0.2	-0.6
Whole body fat-free mass	0.1	0.4	0.9	0.0	-0.9
Leg fat-free mass (right)	0.1	0.5	0.8	0.4	-0.9
Whole body water mass	0.1	0.5	0.9	0.1	-0.9
Leg predicted mass (right)	0.1	0.5	0.8	0.3	-0.9
Hearing aid user	0.1	0.1	0.3	0.5	0.2
Mother’s age at death	0.1	0.1	0.2	-0.4	0.1
Financial situation satisfaction	0.1	0.1	0.2	0.4	-0.3
Medication: Blood pressure	0.1	0.2	0.2	0.5	0.3
Medication: Bendroflumethiazide	0.1	0.2	0.4	-0.6	-0.1
Risk taking	0.1	0.1	0.2	0.1	0.4
Diastolic blood pressure, automated reading	0.1	0.4	0.8	0.9	0.1
Cholesterol lowering medication	0.1	0.2	0.3	0.2	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	0.5	0.2
Impedance of whole body	0.1	0.3	0.4	-0.4	0.6
Leg fat mass (left)	0.1	0.3	0.4	0.5	0.6
Bipolar Disorder or Schizophrenia	0.0	0.1	0.1	-0.3	0.0
Depressed Affect (Nagel 2018)	0.0	0.1	0.2	-0.1	-0.4
Major Depression (MDD)	0.0	0.0	0.0	0.0	-0.1
BMI	0.0	0.2	0.4	0.1	0.7
Hair Pigment	0.0	0.4	0.8	0.4	0.9
Tanning	0.0	0.6	1.1	0.2	1.0
Average weekly fortified wine intake	0.0	0.0	0.0	0.2	0.2
Age when periods started (menarche)	0.0	0.1	0.1	0.2	-0.3
Stomach or abdominal pain in last month	0.0	0.0	0.0	-0.2	-0.2
Noisy workplace	0.0	0.0	0.1	-0.0	0.2
Impedance of arm (left)	0.0	0.0	0.0	0.1	0.2
Length of working week for main job	0.0	0.0	0.0	-0.2	-0.0
Pulse wave reflection index	0.0	0.0	0.1	0.1	-0.3
Mouth/teeth dental problems: Bleeding gums	0.0	0.0	0.1	-0.2	-0.2
Arm fat-free mass (right)	0.0	0.0	0.0	-0.1	-0.2
Comparative body size at age 10	0.0	0.0	0.0	-0.1	-0.2
Worry too long after embarrassment	0.0	0.0	0.0	0.1	-0.2
Arm predicted mass (right)	0.0	0.0	0.0	-0.1	-0.1
Pulse rate, automated reading	0.0	0.1	0.3	0.0	0.5
Alcohol intake frequency.	0.0	0.1	0.1	0.2	-0.3
Comparative height size at age 10	0.0	0.1	0.1	-0.4	-0.3
Illnesses of siblings: Diabetes	0.0	0.0	0.0	0.2	-0.0
Smoking status: Previous	0.0	0.0	0.0	0.1	-0.0
Mood swings	0.0	0.0	0.0	-0.1	-0.0
Eye problems/disorders: Cataract	0.0	0.1	0.1	-0.3	0.1
Medication for cholesterol	0.0	0.1	0.1	-0.1	0.3
Illnesses of father: None of the above (group 1)	0.0	0.0	0.0	0.0	0.2
Basal metabolic rate	0.0	0.3	0.5	0.2	-0.7
Arm fat-free mass (left)	0.0	0.1	0.1	0.1	-0.4
Ever depressed for a whole week	0.0	0.0	0.1	-0.1	0.3
Unable to work because of sickness or disability	0.0	0.0	0.0	0.1	0.1
Arm predicted mass (left)	0.0	0.2	0.5	0.1	-0.7

Hub : Genes

MAP3K8

Models

Trait associations