Hub : Genes

MAP7

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Aorta 0.1460 0.0480 2.2e-05 0.140 NA 0.136 NA 0.144 3.9e-08 NA 6.2e-08 NA 2.5e-08
2 GTEx Artery Tibial 0.1847 0.0366 1.1e-16 0.284 NA 0.305 NA 0.303 1.7e-22 NA 2.6e-24 NA 4.0e-24
3 GTEx Esophagus Muscularis 0.1480 0.0430 4.9e-07 0.113 NA 0.133 NA 0.142 2.3e-07 NA 1.8e-08 NA 6.3e-09
4 GTEx Heart Atrial Appendage 0.0830 0.0390 9.2e-03 0.090 NA 0.074 NA 0.082 7.3e-05 NA 3.3e-04 NA 1.6e-04
5 GTEx Heart Left Ventricle 0.2135 0.0616 4.1e-07 0.152 NA 0.155 NA 0.159 1.9e-08 NA 1.2e-08 NA 7.9e-09
6 GTEx Nerve Tibial 0.1039 0.0408 3.0e-04 0.028 NA 0.047 NA 0.089 4.2e-03 NA 2.8e-04 NA 7.8e-07
7 METSIM Adipose 0.0688 0.0302 1.4e-03 0.027 0.014 0.024 0.020 0.018 5.1e-05 0.0027 1.2e-04 0.00045 7.3e-04
8 YFS Blood 0.0331 0.0156 1.9e-03 0.007 0.005 0.005 0.006 0.004 2.2e-03 0.0073 5.6e-03 0.00240 1.4e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.1 0.2 1.0 -0.3 -0.1 0.1 -0.1 -0.3 -0.4 0.6 -1.0
Bipolar Disorder or Schizophrenia 0.3 0.8 2.0 -1.0 -1.1 -0.8 -1.1 -1.4 -0.7 -0.4 -0.4
Depressed Affect (Nagel 2018) 0.3 0.6 2.2 -0.2 -0.5 -0.7 -0.5 -0.2 -1.5 -0.2 1.1
Depression (Nagel 2018) 0.1 0.1 0.8 0.1 0.1 0.1 0.3 0.2 -0.4 -0.1 -0.9
Intelligence (Savage-Jansen 2018) 1.2 3.6 8.3 2.9 2.3 2.1 2.2 0.9 1.3 1.7 -0.5
Neuroticism (Nagel 2018) 0.3 0.7 1.2 -0.2 -0.7 -0.9 -0.8 -1.1 -1.1 0.2 1.0
Schizophrenia (2018) 0.6 1.3 2.5 -1.0 -1.3 -1.2 -1.3 -1.6 -1.0 -0.9 0.2
Schizophrenia vs Biploar Disorder 0.7 0.9 4.6 0.1 -0.3 -0.6 -0.5 -0.8 0.4 -1.2 2.1
Worry (Nagel 2018) 0.6 1.3 3.1 -0.9 -1.2 -1.4 -1.4 -1.8 -0.6 -0.6 0.5
Alzheimer’s Disease (in mother) 0.3 0.3 0.9 -0.1 -0.2 -0.0 -0.0 -0.9 -0.8 -0.8 0.8
Alzheimer’s Disease (in father) 0.7 0.8 1.6 -1.3 -1.1 -1.2 -1.2 -0.3 -0.6 -0.2 -0.0
Alzheimer’s Disease (including proxy) 0.1 0.2 0.5 -0.3 -0.2 -0.2 -0.1 -0.4 -0.6 -0.7 0.7
Crohns Disease (2017) 0.3 0.7 4.0 0.3 0.1 0.0 -0.0 -0.4 1.1 -0.7 -2.0
Irritable Bowel Disease (IBD) 0.4 0.9 3.7 0.3 0.3 0.2 0.1 0.6 1.3 -1.2 -1.9
Ulcerative Colitis (UC) 0.2 0.3 1.1 0.0 0.0 0.1 -0.1 1.0 0.3 -0.9 -0.8
Major Depression (MDD) 0.3 0.4 1.7 0.1 0.4 0.6 0.2 0.6 0.3 1.3 -0.4
Reaction Time 0.7 1.4 6.5 0.2 -0.0 -0.1 -0.1 -0.1 -0.3 -2.6 2.1
Verbal and Numeric Reasoning (VNR) 0.8 1.9 4.9 2.2 1.6 1.4 1.6 0.2 1.0 1.4 0.2
Breast Cancer 1.6 3.9 5.4 -2.3 -2.2 -2.2 -2.2 -2.0 -0.8 -2.0 1.6
Ovarian Cancer 1.2 1.6 3.5 -1.4 -1.3 -1.1 -1.1 -0.7 -1.9 -0.6 1.8
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.3 0.5 1.7 -0.1 -0.4 -0.5 -0.7 -1.3 0.8 -0.5 -0.5
Bipolar Disorder (2011) 0.7 0.7 3.3 0.3 0.5 0.6 0.6 0.1 0.5 1.8 -0.9
Body Mass Index (BMI) (2010) 0.3 0.4 1.4 -0.2 -0.3 -0.3 -0.2 -0.9 -0.4 -1.2 -0.4
Coronary Artery Disease (CAD) 0.4 0.5 3.1 0.4 0.5 0.3 0.1 -0.1 1.8 0.1 0.2
Crohns Disease (2012) 0.1 0.2 1.4 -0.0 -0.1 -0.2 -0.2 -0.3 0.1 -0.2 -1.2
Mean Putamen Volume 0.5 0.6 2.0 -0.1 0.0 0.1 0.2 1.4 1.1 -0.0 -1.2
Fasting Glucose 0.5 0.6 3.0 -0.4 -0.5 -0.6 -0.6 -0.3 -0.8 -1.7 0.1
HbA1C 0.3 0.3 0.8 -0.7 -0.7 -0.5 -0.4 -0.4 -0.9 -0.5 -0.2
HDL Cholesterol 0.6 0.9 4.8 0.2 0.1 0.2 0.2 0.1 -0.4 2.2 1.6
LDL Cholesterol 0.5 0.8 2.8 0.5 0.9 0.9 0.7 0.3 1.7 -0.1 -0.9
Lupus 0.5 0.8 2.0 1.0 0.9 0.8 0.8 0.8 1.4 0.8 0.1
Neuroticism (2016) 0.2 0.2 1.1 0.3 0.3 0.2 0.4 0.5 -1.1 0.5 0.1
Primary Biliary Cirrhosis 0.1 0.2 0.5 -0.4 -0.3 -0.4 -0.3 -0.7 0.2 0.2 0.4
Rheumatoid Arthritis 0.4 0.5 1.1 -0.8 -0.9 -1.0 -0.9 -0.6 -0.1 -0.1 0.6
Schizophrenia (2014) 1.2 2.7 4.5 -1.8 -2.1 -1.9 -2.1 -1.5 -1.1 -1.3 0.7
Triglycerides 0.7 1.1 2.1 -1.1 -1.0 -0.9 -1.2 -1.5 -0.8 -1.2 -0.1
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.7 -0.0 -0.0 -0.1 -0.2 -0.8 0.3 0.8 0.1
Ulcerative Colitis 0.2 0.3 0.9 -0.4 -0.4 -0.5 -0.7 0.9 0.3 -0.3 -0.3
Blood Eosinophil Count 0.2 1.4 2.3 1.5 1.4 1.1 1.2 0.4 1.4 0.6 -1.4
Blood Platelet Count 0.9 10.0 37.9 1.6 1.3 1.3 1.7 2.2 -0.5 5.3 6.2
Blood Red Count 0.1 0.8 3.9 1.0 0.5 0.0 0.3 -0.6 -0.6 -0.7 -2.0
Blood White Count 0.3 2.3 6.8 1.7 1.5 1.3 1.6 1.5 -0.3 2.6 -0.5
Heel T-Score 0.5 4.3 7.6 1.7 2.4 2.6 2.5 1.9 2.8 1.2 0.3
BMI 1.0 5.5 7.8 -2.8 -2.7 -2.6 -2.5 -1.8 -2.4 -1.4 2.4
Height 0.0 0.8 5.9 -0.5 0.0 0.4 0.2 0.1 0.1 0.6 2.4
Waist Hip Ratio (WHR) 0.1 0.3 0.7 0.8 0.6 0.3 0.6 0.6 -0.3 0.1 -0.2
Systolic Blood Pressure 0.3 1.5 3.3 -0.9 -1.2 -1.4 -1.3 -1.8 -1.6 -0.1 0.5
Smoking Status 0.2 0.4 1.4 0.8 0.6 0.5 0.5 1.2 0.1 -0.3 0.3
Allergy or Eczema 0.3 0.8 4.1 0.3 0.2 -0.2 -0.2 -0.1 1.3 0.5 -2.0
Cardiovascular Disease 0.1 0.4 1.5 0.7 0.5 0.4 0.6 -0.2 -0.1 -1.2 0.1
Hypothyroidism (self reported) 0.3 0.8 1.9 0.8 0.9 0.6 0.8 1.0 1.4 0.3 0.9
Respiratory disease 1.4 3.1 4.3 -1.6 -1.9 -2.0 -1.8 -1.9 -2.1 0.7 1.7
Type 2 Diabetes (T2D) (2018) 1.5 2.8 3.6 -1.4 -1.9 -1.9 -1.9 -1.7 -1.3 -1.3 1.8
Lung FEV1/FVC ratio 0.3 1.5 2.6 -1.1 -1.4 -1.5 -1.4 -1.6 -0.9 -1.0 -0.1
Lung FVC 2.3 11.8 16.3 3.7 4.0 4.0 4.0 3.5 3.7 2.4 -0.9
Neuroticism 0.1 0.1 0.6 0.2 -0.1 -0.3 -0.1 -0.4 -0.1 -0.8 0.4
Chronotype (morning person) 0.0 0.1 0.4 0.1 0.2 0.3 0.2 -0.6 0.0 -0.6 -0.1
Hair Pigment 0.2 6.0 8.9 2.1 2.5 2.7 2.5 3.0 2.3 1.2 -2.7
Tanning 0.2 2.6 12.9 1.1 1.1 0.9 0.9 1.4 0.8 3.6 1.1
Hand grip strength (left) 0.2 0.5 1.9 -0.8 -0.7 -0.6 -0.7 -0.3 0.2 0.3 1.4
Number of treatments/medications taken 1.5 2.8 10.9 -0.9 -1.5 -1.7 -1.5 -1.3 -1.0 -3.3 0.1
Average weekly spirits intake 0.3 0.4 1.2 0.0 -0.3 -0.4 -0.2 -0.6 -0.6 1.1 0.8
Sensitivity / hurt feelings 0.1 0.1 0.7 0.3 0.3 0.1 0.2 -0.0 -0.2 0.4 0.9
Frequency of depressed mood in last 2 weeks 0.1 0.2 0.7 -0.0 -0.2 -0.4 0.1 -0.3 -0.4 -0.4 -0.8
Hearing difficulty/problems: Yes 1.0 1.5 2.8 1.7 1.5 1.5 1.5 1.0 0.4 1.1 -0.1
Relative age of first facial hair 0.5 1.1 1.7 -1.3 -1.2 -1.1 -1.2 -1.1 -1.0 0.8 -0.1
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 1.7 1.0 0.6 0.4 0.5 0.0 1.3 1.2 -0.7
Ever used hormone-replacement therapy (HRT) 0.6 0.8 3.0 0.4 0.5 0.6 0.6 0.1 1.4 0.1 -1.7
Ever had hysterectomy (womb removed) 0.4 0.4 1.0 -0.7 -0.6 -0.6 -0.5 -1.0 0.3 0.5 0.7
Systolic blood pressure, automated reading 1.8 5.2 9.2 -2.2 -2.7 -2.8 -2.7 -2.2 -3.0 0.1 0.4
Eye problems/disorders: Diabetes related eye disease 1.2 1.3 2.1 -1.3 -1.1 -0.8 -0.9 -1.0 -1.4 -1.3 1.1
Angina 0.4 0.6 1.2 1.0 0.6 0.4 0.6 0.4 -1.1 1.1 -0.4
Medication for hormone replacement therapy 0.5 0.6 1.7 0.4 0.7 0.6 1.0 1.3 -0.0 -0.4 -0.8
Vitamin and mineral supplements 0.5 0.6 2.0 -0.1 -0.6 -0.8 -0.5 -1.4 -0.7 -1.0 0.5
Supplements: Zinc 2.2 2.4 3.5 -1.9 -1.7 -1.9 -1.8 -1.6 0.1 -1.2 1.3
Medication: Co-codamol 0.3 0.4 1.5 -0.6 -0.3 0.1 -0.2 -0.2 -0.2 1.2 0.9
Medication: Metformin 0.5 0.7 4.1 -0.3 -0.3 -0.2 -0.2 -0.1 -1.2 -0.0 2.0
Diabetes (father) 2.6 3.2 6.2 -2.0 -2.0 -2.1 -1.8 -1.5 -0.8 0.4 2.5
Diabetes (mother) 1.7 2.2 3.3 -1.8 -1.8 -1.7 -1.6 -1.6 -1.6 -0.6 0.2
Severe depression (siblings) 1.5 1.7 5.0 -0.8 -1.2 -1.4 -1.1 -1.2 -2.2 0.2 1.4
Pack years adult smoking proportion 0.2 0.3 2.0 -0.2 -0.1 -0.2 -0.2 0.2 0.1 1.4 0.1
Impedance of leg (right) 0.2 0.8 2.2 0.9 0.8 0.7 0.6 0.4 1.5 1.0 -1.0
Leg fat-free mass (left) 0.3 1.7 3.8 -1.3 -1.3 -1.2 -1.2 -1.1 -1.6 -0.1 1.9
Trunk fat percentage 1.4 5.7 8.8 -2.6 -2.9 -3.0 -2.7 -2.4 -2.7 -1.1 0.6
Hand grip strength (right) 0.2 0.4 1.9 -0.4 -0.3 -0.3 -0.4 -0.3 0.9 -0.5 1.4
Townsend deprivation index at recruitment 0.1 0.1 0.4 0.5 0.3 0.1 0.3 0.1 -0.6 0.1 0.4
Current tobacco smoking 0.1 0.2 1.4 -0.2 0.0 -0.0 0.0 -0.0 -0.1 1.2 0.2
Average weekly fortified wine intake 0.5 0.6 3.2 0.7 0.4 0.4 0.6 -0.4 0.1 0.6 -1.8
Maternal smoking around birth 0.8 1.2 4.8 0.9 0.9 0.9 1.1 0.9 -0.5 2.2 -0.3
Fed-up feelings 0.3 0.5 2.1 0.3 0.1 -0.0 0.2 0.3 -1.1 -1.4 -0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 0.8 -0.1 -0.1 -0.1 0.1 0.1 -0.9 -0.9 -0.8
Relative age voice broke 0.1 0.2 1.0 0.1 0.3 0.1 0.2 -0.5 0.0 1.0 -0.1
Taking other prescription medications 2.7 4.1 6.9 -1.9 -2.5 -2.6 -2.4 -2.4 -1.2 -1.1 1.6
Age when periods started (menarche) 0.1 0.3 0.7 0.4 0.1 0.0 -0.1 -0.4 0.7 0.8 0.8
Bilateral oophorectomy (both ovaries removed) 0.4 0.4 1.7 -0.8 -0.5 -0.6 -0.6 -1.3 0.3 0.3 0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 2.2 -0.4 -0.1 0.2 -0.0 0.2 -0.5 1.5 -0.1
Tinnitus: Yes, but not now, but have in the past 0.1 0.1 0.3 -0.5 -0.1 -0.1 -0.2 0.0 0.0 0.5 0.1
Qualifications: CSEs or equivalent 0.5 0.6 1.5 1.0 0.7 0.4 0.5 0.4 1.2 -1.2 -0.0
Serious illness, injury or assault to yourself 0.8 1.0 3.5 -0.5 -0.8 -1.0 -0.9 -1.1 -0.1 0.7 1.9
High blood pressure 0.8 2.2 4.7 -1.1 -1.5 -1.6 -1.3 -1.8 -2.2 -1.2 0.6
Hayfever, allergic rhinitis or eczema 0.2 0.4 1.8 -0.4 -0.4 -0.6 -0.3 -0.5 0.0 0.2 -1.3
Multivitamins +/- minerals 0.5 0.6 2.7 -0.3 0.3 0.7 0.3 1.6 0.9 0.7 -0.1
Stomach or abdominal pain in last month 0.8 1.0 1.7 -0.9 -1.0 -1.2 -1.2 -1.3 -0.2 0.3 1.3
Supplements: Glucosamine 0.4 0.5 1.5 0.7 0.7 0.7 0.7 0.2 1.2 0.8 -0.3
Diverticular disease/diverticulitis (self-reported) 1.1 1.3 8.2 0.6 0.2 0.2 0.3 0.4 -0.7 1.1 2.9
Medication: Atenolol 1.0 1.3 1.9 -1.4 -1.2 -1.1 -1.3 -1.3 -1.1 -0.4 0.9
Medication: Levothyroxine sodium 1.8 3.0 5.4 -1.9 -2.1 -2.3 -2.1 -1.4 -1.3 0.4 1.6
Sitting height 0.2 1.4 3.1 1.4 1.4 1.2 1.1 0.8 1.8 0.0 0.9
Chronic bronchitis/emphysema (father) 0.4 0.5 1.0 -1.0 -0.8 -0.7 -0.9 -0.6 -0.5 -0.3 0.3
High blood pressure (mother) 0.6 0.8 1.8 -0.7 -0.9 -1.3 -1.1 -1.3 0.6 -0.3 -0.7
Body mass index (BMI) 1.1 4.8 7.5 -2.3 -2.5 -2.6 -2.3 -2.1 -2.7 -1.3 1.0
Impedance of leg (left) 0.2 1.0 2.6 0.9 0.8 0.8 0.7 0.3 1.6 0.8 -1.4
Leg predicted mass (left) 0.3 1.7 3.3 -1.3 -1.3 -1.3 -1.2 -1.2 -1.6 -0.1 1.8
Trunk fat mass 1.4 6.1 8.8 -2.7 -2.9 -3.0 -2.8 -2.4 -2.9 -1.0 1.2
Waist circumference 0.8 2.8 6.1 -1.6 -1.9 -2.0 -1.6 -1.4 -2.5 -0.6 1.2
Number of incorrect matches in round 3.7 6.1 8.6 -2.5 -2.6 -2.5 -2.8 -2.7 -2.9 -2.0 1.4
Past tobacco smoking 0.3 0.5 1.6 -0.9 -0.5 -0.4 -0.5 -0.9 0.0 1.2 -0.2
Alcohol usually taken with meals 1.0 1.6 3.5 0.9 1.5 1.5 1.5 1.3 1.9 -0.3 0.6
Nervous feelings 0.3 0.6 2.6 0.6 0.2 0.0 0.1 -0.5 0.4 -1.3 -1.6
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 2.7 0.5 0.4 0.3 0.4 -0.1 -0.1 -0.7 -1.6
Hearing difficulty/problems with background noise 0.2 0.4 0.9 -0.1 -0.5 -0.8 -0.6 -0.9 0.2 -0.9 0.4
Hair/balding pattern: Pattern 2 0.8 1.0 6.7 -0.4 -0.6 -0.6 -0.6 -0.4 0.5 0.3 2.6
Had menopause 0.1 0.1 0.2 -0.1 -0.2 -0.2 -0.3 -0.1 -0.5 -0.3 -0.0
Had other major operations 0.4 0.5 2.4 0.2 0.5 0.6 0.6 1.5 0.2 0.7 0.7
Forced vital capacity (FVC) 2.6 10.1 14.8 3.5 3.9 3.8 3.7 3.1 3.6 1.6 -0.7
Heel bone mineral density (BMD) T-score, automated (right) 0.0 0.1 0.2 -0.0 0.2 0.4 0.2 0.3 -0.1 0.3 -0.4
Ever unenthusiastic/disinterested for a whole week 2.2 2.7 4.1 -1.3 -1.7 -1.8 -1.7 -1.9 -1.8 -2.0 -0.7
Qualifications: None of the above 3.4 7.2 10.1 -3.2 -3.1 -3.2 -3.2 -2.5 -2.6 -2.0 1.1
Financial difficulties in last 2 years 0.7 0.9 1.9 -1.3 -1.2 -1.0 -0.8 -0.7 -1.4 -0.6 -0.0
Mouth/teeth dental problems 0.1 0.1 0.4 0.3 0.3 0.3 0.2 -0.4 -0.3 0.6 0.2
Heart attack 0.4 0.5 2.7 -0.1 -0.3 -0.4 -0.3 -0.7 -1.7 -0.1 -0.5
Allergy 0.1 0.2 1.0 0.2 0.3 0.4 0.2 0.5 0.1 -1.0 0.3
Pain all over the body in last month 1.4 1.5 4.9 -1.2 -1.4 -1.2 -1.1 0.1 -2.2 -0.9 0.7
Diabetes (self-reported) 1.6 2.4 3.5 -1.2 -1.6 -1.7 -1.5 -1.9 -1.3 -1.3 1.8
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 0.6 -0.6 -0.5 -0.5 -0.6 -0.8 0.2 -0.6 -0.5
Medication: Ramipril 1.2 1.5 6.4 0.2 -0.6 -1.1 -0.8 -1.0 -1.2 -2.5 1.1
Medication: Simvastatin 0.2 0.3 0.6 0.7 0.6 0.6 0.6 0.1 -0.2 0.4 -0.6
Fluid intelligence score 1.5 3.0 5.9 2.4 2.1 1.9 2.1 0.4 1.7 1.5 -0.6
Illnesses of siblings 1.5 2.1 4.2 1.9 1.5 1.2 1.4 1.2 2.0 1.4 0.4
Neuroticism score 0.1 0.3 2.1 0.3 0.1 -0.0 0.2 -0.4 -0.2 -1.5 0.1
Weight 1.1 5.2 7.3 -2.3 -2.5 -2.5 -2.4 -2.3 -2.7 -0.8 2.1
Impedance of arm (right) 0.1 0.4 0.8 0.9 0.7 0.5 0.7 0.3 0.9 0.7 -0.4
Arm fat percentage (right) 1.3 5.1 9.2 -2.2 -2.6 -2.8 -2.4 -2.2 -3.0 -1.2 0.6
Trunk fat-free mass 0.2 1.2 5.3 -0.8 -0.8 -0.7 -0.8 -0.9 -1.2 0.1 2.3
Hip circumference 1.1 4.6 6.4 -2.2 -2.4 -2.5 -2.4 -2.2 -2.3 -1.3 1.6
Time employed in main current job 1.4 1.6 4.1 0.8 1.1 1.1 1.1 1.0 1.4 -1.2 -2.0
Alcohol intake versus 10 years previously 0.3 0.5 0.9 0.9 0.8 0.7 0.6 0.0 0.8 0.4 0.9
Father’s age at death 0.1 0.2 0.4 0.4 0.5 0.5 0.6 0.1 -0.3 -0.0 0.5
Worrier / anxious feelings 0.2 0.5 1.1 -0.4 -0.6 -0.6 -0.6 -1.1 -0.5 -0.9 -0.6
Frequency of tiredness / lethargy in last 2 weeks 1.0 1.7 2.8 -1.7 -1.6 -1.4 -1.3 -1.1 -1.1 -1.6 -0.0
Falls in the last year 0.2 0.3 1.0 -0.0 -0.4 -0.5 -0.1 1.0 -0.5 -0.3 0.6
Hair/balding pattern: Pattern 3 1.3 2.0 4.4 1.0 1.5 1.9 1.5 1.5 0.6 -0.3 -2.1
Number of live births 0.6 0.9 1.7 -1.2 -1.2 -1.3 -1.1 -0.8 -0.3 -0.3 0.6
Forced expiratory volume in 1-second (FEV1) 1.7 5.6 9.1 2.6 2.8 2.8 2.7 2.2 3.0 1.0 -0.7
Pulse rate 1.7 2.9 3.9 1.8 1.8 1.9 1.9 2.0 0.3 1.6 -1.6
Happiness 0.5 0.7 4.3 -0.4 -0.3 -0.3 -0.3 0.6 0.1 0.1 -2.1
Noisy workplace 0.4 0.5 1.3 0.7 0.7 0.6 0.7 1.2 0.9 0.0 -0.5
Qualifications: A levels/AS levels or equivalent 0.6 1.3 3.4 1.9 1.3 0.8 1.0 0.2 1.8 0.1 0.6
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.7 0.4 -0.0 -0.3 0.0 -0.5 -0.1 0.7 0.8
Mouth/teeth dental problems: Dentures 0.2 0.3 0.6 -0.8 -0.7 -0.7 -0.6 0.3 -0.5 -0.1 -0.1
Asthma 1.1 2.3 3.1 -1.5 -1.8 -1.8 -1.6 -1.6 -1.5 0.8 1.2
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 3.8 -0.2 0.1 0.4 0.3 1.1 0.2 -0.1 -1.9
Medication: Cholesterol lowering 0.2 0.3 1.5 0.5 0.2 0.1 0.1 -0.1 -1.2 0.1 0.6
Depression (self-reported) 0.2 0.2 0.9 0.7 0.3 -0.0 0.1 -0.2 0.9 -0.5 -0.4
Medication: Lansoprazole 1.2 1.4 3.3 -0.8 -1.2 -1.3 -1.4 -1.8 -0.2 -0.9 -1.2
Prospective memory result 0.4 0.5 2.9 -0.5 -0.3 -0.2 -0.2 -0.2 0.0 -1.7 -0.7
Lung cancer (father) 0.8 0.9 4.3 -0.9 -0.7 -0.6 -0.7 -0.7 -0.4 -2.1 -0.0
Illnesses of mother 1.1 1.4 3.0 1.0 1.3 1.4 1.3 1.7 0.8 0.6 -0.8
Forced expiratory volume in 1-second (FEV1), Best measure 1.9 5.9 9.1 2.6 3.0 3.0 2.9 2.3 2.8 0.9 -0.4
Pulse wave Arterial Stiffness index 0.4 0.5 0.9 -0.7 -0.7 -0.8 -0.7 -1.0 -0.8 -0.3 0.3
Impedance of arm (left) 0.0 0.2 0.7 0.4 0.3 0.3 0.4 0.0 0.7 0.8 -0.3
Arm fat mass (right) 1.2 5.1 8.0 -2.3 -2.6 -2.7 -2.4 -2.3 -2.8 -0.9 1.3
Trunk predicted mass 0.2 1.3 5.4 -0.8 -0.8 -0.7 -0.8 -0.9 -1.2 0.1 2.3
Standing height 0.1 0.9 6.3 -0.4 -0.3 -0.2 -0.4 -0.6 -0.1 0.6 2.5
Length of working week for main job 0.4 0.4 1.4 0.4 0.4 0.2 0.3 -0.4 1.2 -0.6 -1.1
Exposure to tobacco smoke at home 1.2 1.3 2.3 -1.5 -1.4 -1.4 -1.5 -0.9 -0.4 -0.1 -1.0
Breastfed as a baby 2.7 3.3 6.5 -2.6 -2.0 -1.9 -2.2 -2.5 -1.1 -0.2 0.4
Tense / ‘highly strung’ 0.5 0.8 1.6 -1.1 -0.9 -0.8 -0.7 -1.3 -0.8 -0.8 -0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 2.6 4.0 6.4 -2.4 -2.3 -2.3 -2.4 -2.5 -1.1 -1.0 0.6
Hair/balding pattern: Pattern 4 0.2 0.5 0.8 0.7 0.8 0.7 0.8 -0.1 0.9 0.4 0.9
Birth weight of first child 0.5 1.0 2.7 -1.6 -1.2 -0.9 -1.1 -1.0 -0.6 -0.6 0.0
Peak expiratory flow (PEF) 1.7 4.1 5.9 2.0 2.3 2.4 2.3 2.4 1.9 1.3 -0.8
Pulse wave reflection index 1.4 1.8 2.8 -1.2 -1.4 -1.4 -1.5 -1.7 -1.6 -0.9 0.8
Ever highly irritable/argumentative for 2 days 1.6 1.9 4.5 -1.6 -1.5 -1.3 -1.2 -1.1 -2.1 0.7 1.0
Loud music exposure frequency 0.5 0.5 3.2 0.1 0.1 0.1 0.1 -0.1 0.6 -1.8 -0.6
Qualifications: O levels/GCSEs or equivalent 0.2 0.4 1.3 1.1 0.5 0.2 0.4 0.0 0.5 0.9 0.4
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 0.6 -0.6 -0.7 -0.8 -0.7 -0.4 0.1 -0.3 0.5
Blood clot in the leg (DVT) 1.2 1.5 4.6 1.0 0.9 0.8 0.8 0.2 -0.5 2.2 2.0
Medication: Paracetamol 0.3 0.6 2.6 -0.1 0.2 0.3 0.1 0.3 1.0 0.8 -1.6
Headache pain in last month 1.7 2.8 7.9 -1.2 -1.7 -1.9 -1.6 -1.8 -2.8 -0.8 0.3
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 2.6 -0.0 0.3 0.4 0.3 0.5 1.6 1.4 -0.6
Glaucoma (self-reported) 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.4 -0.4
Gout (self-reported) 3.2 4.4 9.0 -3.0 -2.8 -2.5 -2.8 -1.8 -0.8 -0.1 -0.0
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 0.5 -0.2 -0.4 -0.7 -0.4 -0.1 0.3 0.4 0.5
Medication: Amlodipine 0.4 0.5 2.3 -0.0 -0.3 -0.3 -0.3 -0.7 0.3 -1.5 -0.9
Medication: Ventolin 100micrograms inhaler 0.3 0.3 0.9 0.7 0.1 -0.4 -0.3 -0.7 0.4 0.6 0.9
Birth weight 0.3 0.6 2.6 0.2 -0.1 -0.1 -0.1 -1.3 -0.2 -1.6 -0.2
Chronic bronchitis/emphysema (mother) 0.8 1.0 1.4 -1.0 -1.0 -0.9 -1.0 -1.2 -0.9 -0.9 0.9
High blood pressure (siblings) 2.3 3.3 5.0 -2.2 -2.1 -2.0 -2.1 -1.6 -2.2 -1.2 -0.6
Forced vital capacity (FVC), Best measure 1.8 6.6 10.6 2.7 3.2 3.3 3.0 2.5 2.8 1.3 -0.3
Body fat percentage 1.5 6.0 9.1 -2.6 -2.9 -3.0 -2.7 -2.4 -3.0 -1.0 0.6
Leg fat percentage (right) 1.8 6.6 10.3 -2.6 -3.0 -3.1 -2.9 -2.7 -3.2 -1.2 0.4
Arm fat-free mass (right) 0.2 1.2 2.7 -1.2 -1.1 -0.9 -1.1 -0.9 -1.1 0.4 1.6
Exposure to tobacco smoke outside home 0.5 0.7 3.4 0.7 0.1 -0.1 0.3 0.5 -1.8 -0.2 1.1
Comparative body size at age 10 0.4 1.0 2.3 1.5 1.2 1.0 1.1 0.4 1.2 -0.6 0.0
Number of full brothers 0.6 0.7 2.9 -0.5 -0.3 -0.3 -0.5 -0.1 1.4 -0.3 -1.7
Worry too long after embarrassment 0.6 1.0 1.9 1.4 1.2 1.1 1.2 -0.2 1.4 -0.3 -0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 2.4 -0.4 -0.6 -0.7 -0.6 -1.0 -0.2 0.6 1.6
Wheeze or whistling in the chest in last year 1.0 1.8 2.9 -1.4 -1.5 -1.4 -1.2 -1.1 -1.7 -0.1 -1.7
Number of children fathered 0.3 0.4 1.6 -0.5 -0.2 -0.1 -0.1 0.5 -1.3 0.6 0.8
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 1.8 0.5 0.6 0.7 0.7 1.3 1.3 1.2 0.1
Age at first live birth 0.5 1.0 1.7 1.2 1.0 0.9 0.9 0.4 1.3 1.3 -0.2
Pulse wave peak to peak time 0.3 0.3 0.7 0.6 0.6 0.7 0.6 0.9 0.5 0.4 -0.1
Health satisfaction 0.4 0.5 2.5 0.6 0.3 0.2 0.5 0.7 -0.0 0.1 -1.6
Shortness of breath walking on level ground 0.2 0.2 0.5 0.7 -0.1 -0.6 -0.1 -0.0 0.0 0.6 0.5
Qualifications: College or University degree 0.9 2.8 4.5 2.1 2.0 1.9 1.9 1.4 1.5 -0.5 -1.3
Eye problems/disorders: None of the above 0.6 0.6 1.7 1.1 0.9 0.7 0.8 0.5 0.1 1.3 0.2
Mouth/teeth dental problems: Loose teeth 0.2 0.2 0.6 0.7 0.1 -0.2 0.2 -0.4 -0.6 -0.3 0.8
Emphysema/chronic bronchitis 0.8 0.9 5.9 -0.1 -0.3 -0.4 -0.5 -0.4 -0.8 0.5 2.4
Medication for pain relief, constipation, heartburn 0.4 0.6 2.2 -0.2 -0.2 -0.2 -0.2 -1.5 -0.7 -1.0 1.0
Neck or shoulder pain in last month 0.8 1.2 2.1 -1.4 -1.3 -1.3 -1.3 -1.1 -0.2 0.4 0.8
Medication: Blood pressure 0.6 1.1 3.3 -0.2 -0.5 -0.6 -0.5 -1.1 -1.7 -1.8 0.4
Angina (self-reported) 0.4 0.5 1.5 0.9 0.4 0.2 0.5 0.2 -1.0 1.2 -0.4
Migraine (self-reported) 0.1 0.2 0.9 -0.2 -0.1 0.2 0.1 0.2 -1.0 0.1 -0.5
Medication: Ibuprofen 0.7 0.8 3.9 0.0 0.1 0.4 0.4 1.0 -0.3 -1.1 -2.0
Medication: Allopurinol 1.2 1.6 3.4 -1.8 -1.6 -1.3 -1.6 -0.9 -0.1 1.1 0.6
Medication: Omeprazole 0.8 1.0 4.4 0.7 0.8 0.8 0.9 2.1 0.5 0.9 -0.0
Medication: Seretide 50 evohaler 0.5 0.6 1.5 -0.9 -0.8 -0.6 -0.8 -1.2 -0.2 -0.2 1.0
Mean time to correctly identify matches 0.9 1.7 7.4 -0.3 -0.6 -0.6 -0.6 -0.6 -0.9 -2.7 1.9
Heart disease (mother) 0.5 0.6 1.1 -0.5 -0.8 -1.0 -0.8 -0.9 -0.6 -0.6 -0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.2 1.4 2.5 -1.6 -1.4 -1.5 -1.4 -0.7 0.5 -1.0 0.9
Whole body fat mass 1.2 5.2 8.5 -2.4 -2.7 -2.7 -2.5 -2.1 -2.9 -0.8 1.1
Leg fat mass (right) 1.5 5.7 9.0 -2.5 -2.8 -2.9 -2.6 -2.3 -3.0 -1.0 1.1
Arm predicted mass (right) 0.3 1.3 2.7 -1.2 -1.1 -1.0 -1.1 -1.1 -1.3 0.1 1.6
Pulse rate, automated reading 0.1 0.3 1.5 0.2 0.2 0.4 0.5 0.4 -1.2 -0.6 0.2
Alcohol intake frequency. 0.1 0.3 1.9 -0.2 -0.3 -0.3 -0.1 -0.2 -1.4 -0.3 -0.4
Comparative height size at age 10 0.1 0.8 2.2 -0.3 -0.4 -0.5 -0.5 -0.3 -1.4 1.1 1.5
Number of full sisters 0.5 0.6 1.0 0.8 0.8 0.8 0.9 1.0 -0.4 -0.7 0.7
Suffer from ‘nerves’ 0.4 0.7 1.3 -0.8 -1.0 -1.0 -0.9 -1.1 -0.6 -0.7 -0.3
Overall health rating 0.1 0.2 0.9 -0.5 -0.7 -0.9 -0.5 -0.2 -0.0 0.0 0.3
Chest pain or discomfort 1.5 2.2 3.9 -1.6 -1.8 -1.9 -1.7 -2.0 -1.1 0.3 -0.4
Had major operations 0.4 0.4 0.9 0.9 0.8 0.7 0.6 0.0 0.5 0.3 -1.0
Age at last live birth 1.0 1.5 2.8 1.5 1.3 1.2 1.2 0.8 1.7 1.1 -0.5
Family relationship satisfaction 0.6 0.7 2.9 -0.4 -0.7 -0.6 -0.6 -1.1 0.3 -1.7 -0.4
Leg pain on walking 0.4 0.5 2.4 0.5 0.0 -0.5 0.0 0.4 0.3 1.6 -0.7
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 0.9 -0.3 -0.0 0.0 0.1 0.2 -0.3 0.9 0.6
Commuting to job workplace: Car/motor vehicle 0.5 0.6 2.8 -0.5 -0.4 -0.2 -0.2 -0.4 -1.1 0.2 1.7
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.0 0.6 0.4 0.2 0.2 0.2 1.0 0.5 0.9
Medication: Aspirin 1.7 2.2 4.5 1.9 1.6 1.3 1.5 2.1 0.8 0.2 -1.3
Supplements: Vitamin C 0.1 0.2 0.6 0.0 -0.2 -0.4 -0.2 -0.3 -0.4 -0.8 0.4
Knee pain experienced in last month 2.3 3.6 5.9 -2.1 -2.2 -2.1 -2.0 -2.4 -1.5 -0.2 1.8
Hypertension (Self-reported) 0.7 1.9 3.4 -1.1 -1.4 -1.6 -1.3 -1.8 -1.9 -1.0 0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 3.1 -0.7 -0.8 -0.7 -0.6 -0.5 -0.6 -1.8 -1.3
Illnesses of father: Heart disease 0.7 0.9 1.9 -0.9 -0.9 -0.7 -0.6 -1.3 -1.4 0.6 1.0
Illnesses of siblings: Diabetes 0.6 0.8 1.5 -0.8 -0.9 -1.0 -0.8 -0.6 -0.8 -0.8 -1.2
Smoking status: Previous 0.3 0.5 2.4 0.7 0.2 0.1 0.2 1.1 -0.2 -1.6 -0.1
Forced expiratory volume in 1-second (FEV1), predicted 1.1 2.3 5.8 1.1 1.3 1.5 1.4 1.2 1.6 -0.8 -2.4
Whole body fat-free mass 0.2 1.4 4.2 -1.1 -1.0 -0.9 -1.0 -1.0 -1.4 0.0 2.0
Leg fat-free mass (right) 0.3 1.6 3.1 -1.2 -1.2 -1.2 -1.1 -1.2 -1.5 -0.2 1.8
Arm fat percentage (left) 1.4 5.5 9.7 -2.4 -2.7 -2.9 -2.5 -2.3 -3.1 -0.9 0.7
Average weekly red wine intake 1.6 2.3 4.1 1.9 2.0 1.9 2.0 1.4 0.5 0.9 -0.5
Handedness (chirality/laterality): Left-handed 0.2 0.2 0.9 0.2 0.1 0.0 0.2 -0.3 -0.2 0.9 -0.6
Mood swings 0.4 0.8 2.1 1.2 0.9 0.7 0.9 1.4 0.8 -0.2 0.3
Loneliness, isolation 0.2 0.3 1.9 0.3 0.2 0.0 0.4 -0.2 -1.4 0.5 0.3
Long-standing illness, disability or infirmity 0.6 0.9 2.0 -0.6 -1.1 -1.4 -1.0 -1.0 -0.9 -0.8 0.7
Ever had bowel cancer screening 0.4 0.5 1.4 -1.0 -0.7 -0.6 -0.7 -0.1 -0.4 0.5 1.2
Diabetes diagnosed by doctor 2.9 4.8 5.2 -2.0 -2.3 -2.3 -2.2 -2.3 -2.0 -2.2 2.1
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 1.3 -0.3 -0.5 -0.4 -0.2 -0.5 -1.2 0.8 -0.2
Friendships satisfaction 0.3 0.4 1.5 1.2 0.7 0.5 0.8 -0.2 0.3 -0.6 -0.2
Qualifications: nursing, teaching 0.3 0.5 1.4 1.2 0.8 0.4 0.7 0.2 0.9 0.1 -0.5
Commuting to job workplace: Walk 0.8 0.8 3.4 0.3 -0.1 -0.5 -0.3 -1.2 1.1 -0.2 -1.9
Eye problems/disorders: Cataract 1.1 1.3 6.2 -0.7 -0.7 -0.7 -0.9 -0.5 -0.3 -2.5 -1.1
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 2.0 -1.4 -1.1 -0.8 -0.9 0.0 -0.4 -0.7 -0.5
Medication for cholesterol 0.8 1.3 1.7 1.2 1.2 1.2 1.0 1.3 1.2 1.2 -0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.9 1.7 -1.0 -1.1 -1.3 -1.1 -1.2 -0.4 0.3 0.1
Back pain experienced in last month 0.5 0.8 1.7 0.5 0.7 0.9 0.9 1.0 0.3 1.3 1.1
Mineral and other dietary supplements 1.3 1.7 6.7 -1.1 -1.2 -1.2 -0.9 -1.1 -2.6 -0.3 0.9
Breast cancer (self-reported) 3.1 3.7 5.8 2.0 2.1 2.0 2.0 1.9 1.6 2.4 -0.5
Asthma (self-reported) 1.2 2.4 3.3 -1.5 -1.8 -1.8 -1.6 -1.7 -1.5 0.9 1.3
Osteoporosis (self-reported) 0.4 0.5 1.3 0.0 -0.6 -1.1 -0.9 -0.8 -0.4 -0.4 0.9
Osteoarthritis (self-reported) 1.1 1.4 2.9 -1.4 -1.3 -1.0 -1.2 -1.2 -1.7 0.7 -0.1
Medication: Aspirin 1.3 1.7 3.6 1.7 1.4 1.1 1.3 1.9 0.7 0.1 -1.2
Medication: Gliclazide 1.8 2.0 5.8 -1.0 -1.2 -1.2 -1.0 -0.6 -1.8 -1.3 2.4
Illnesses of father: None of the above (group 1) 1.2 1.5 3.3 1.8 1.4 1.0 1.2 1.4 1.2 0.6 0.6
Smoking status: Current 0.1 0.1 0.8 -0.2 -0.1 -0.2 -0.1 -0.3 -0.1 0.9 0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 1.0 0.5 0.9 0.9 0.8 0.4 1.0 0.2 0.6
Whole body water mass 0.2 1.2 4.2 -0.9 -0.9 -0.8 -0.8 -1.0 -1.3 0.1 2.1
Leg predicted mass (right) 0.3 1.5 2.9 -1.2 -1.2 -1.2 -1.1 -1.1 -1.4 -0.1 1.7
Arm fat mass (left) 1.1 4.6 7.2 -2.2 -2.5 -2.6 -2.3 -2.1 -2.7 -0.7 1.3
Number of self-reported non-cancer illnesses 0.6 1.0 1.8 -0.7 -1.2 -1.3 -1.0 -1.3 -1.1 -0.9 0.2
Average weekly champagne plus white wine intake 1.2 1.7 4.1 2.0 1.7 1.5 1.6 0.0 1.2 -0.2 -0.0
Miserableness 0.2 0.3 0.9 0.6 0.4 0.3 0.5 1.0 -0.5 0.1 0.4
Guilty feelings 0.2 0.4 1.1 0.3 -0.1 -0.3 -0.1 -0.9 -0.8 -0.5 1.1
Wears glasses or contact lenses 1.0 1.1 2.8 -1.2 -0.9 -0.5 -0.8 -1.0 -1.2 -1.0 1.7
Ever taken oral contraceptive pill 0.9 1.0 3.1 -0.9 -1.0 -1.0 -1.0 -1.8 -0.6 -0.7 0.5
Hearing aid user 0.6 0.7 2.1 1.0 0.5 0.5 0.6 0.7 -0.8 -0.7 1.5
Mother’s age at death 0.2 0.3 1.1 0.5 0.5 0.4 0.3 0.1 1.0 -0.6 0.0
Financial situation satisfaction 0.7 0.8 1.7 1.2 0.7 0.2 0.5 0.6 1.3 -0.9 -1.3
Tinnitus: Yes, now most or all of the time 0.6 0.7 4.2 -0.2 0.2 0.3 -0.0 0.4 2.0 0.1 1.1
Commuting to job workplace: Public transport 1.3 1.6 2.7 1.2 1.3 1.5 1.5 1.6 -0.2 1.3 -0.6
Eye problems/disorders: Glaucoma 0.2 0.2 0.5 -0.7 -0.5 -0.4 -0.6 -0.2 -0.0 0.2 0.5
Medication: Blood pressure 0.3 0.6 1.8 -0.5 -0.8 -0.8 -0.8 -1.3 -0.3 0.1 1.0
Pain type(s) experienced in last month: Hip pain 0.2 0.3 0.5 0.2 0.5 0.7 0.6 0.5 0.4 0.7 0.3
Supplements: Fish oil (including cod liver oil) 0.4 0.5 1.9 0.3 0.5 0.6 0.3 1.0 1.4 0.4 -0.1
High cholesterol (Self-reported) 0.7 1.3 2.5 -0.9 -1.0 -0.9 -0.9 -1.2 -1.3 -1.6 1.3
Medication: Bendroflumethiazide 0.2 0.4 1.1 0.0 -0.2 -0.2 -0.2 -0.7 -0.9 -0.7 -1.0
Medication: Paracetamol 0.6 1.0 4.1 0.5 0.7 0.7 0.7 0.6 1.1 0.6 -2.0
Medication: Lisinopril 1.1 1.4 2.9 -0.9 -0.7 -0.6 -0.7 -1.5 -1.7 -0.8 1.7
Medication: Atorvastatin 0.2 0.3 0.8 -0.3 -0.4 -0.5 -0.4 -0.2 -0.6 -0.9 0.7
Illnesses of father: High blood pressure 1.6 2.0 3.3 -1.6 -1.5 -1.5 -1.5 -1.8 -0.4 -1.8 0.1
Alcohol drinker status: Never 1.0 1.2 3.0 -1.3 -1.3 -0.9 -1.0 -0.8 -1.7 -0.9 0.4
Ever smoked 0.3 0.5 1.4 0.7 0.5 0.5 0.6 0.8 0.3 -1.2 -0.4
Basal metabolic rate 0.4 2.2 4.2 -1.4 -1.5 -1.4 -1.4 -1.4 -1.7 -0.2 2.1
Leg fat percentage (left) 1.7 6.0 9.5 -2.5 -2.8 -2.9 -2.7 -2.7 -3.1 -1.3 0.0
Arm fat-free mass (left) 0.2 0.9 2.7 -0.9 -0.9 -0.9 -1.0 -0.9 -0.9 -0.0 1.6
Number of operations (self-reported) 0.1 0.2 0.7 -0.1 0.3 0.3 0.3 0.2 0.7 0.8 -0.1
Average weekly beer plus cider intake 0.7 1.1 4.2 1.0 0.8 0.7 0.8 1.1 0.5 0.3 -2.0
Irritability 0.1 0.1 0.4 0.2 0.3 0.3 0.4 0.2 0.4 -0.6 -0.1
Risk taking 0.2 0.3 1.1 -0.1 0.3 0.3 0.3 0.9 0.4 -1.1 0.0
Ever had prostate specific antigen (PSA) test 0.4 0.5 1.8 -0.2 -0.2 -0.4 -0.2 -0.9 0.3 1.0 1.3
Fractured/broken bones in last 5 years 0.5 0.7 2.1 0.7 0.6 0.6 0.6 1.0 0.8 0.3 -1.5
Age started oral contraceptive pill 0.6 0.7 2.8 -0.8 -0.9 -0.8 -0.9 -1.7 0.2 -0.3 0.2
Diastolic blood pressure, automated reading 0.3 1.0 2.2 -0.7 -1.0 -1.0 -1.0 -1.3 -1.5 -0.0 -0.8
Ever depressed for a whole week 0.1 0.1 0.4 0.1 -0.2 -0.2 -0.0 -0.4 -0.3 -0.5 -0.6
Unable to work because of sickness or disability 1.7 2.2 3.8 -1.9 -2.0 -1.9 -1.7 -1.0 -1.3 0.2 1.1
Commuting to job workplace: Cycle 0.3 0.3 0.8 0.3 0.4 0.5 0.4 0.1 0.9 -0.9 -0.7
Myopia 1.0 1.4 7.5 -1.1 -1.1 -0.6 -0.8 -0.6 -2.7 -0.4 -0.3
Vascular/heart problems diagnosed by doctor 0.6 1.6 4.6 0.7 1.2 1.2 0.9 1.4 2.2 0.9 -1.1
Cholesterol lowering medication 0.5 0.7 1.2 -1.1 -0.9 -0.8 -0.7 -1.1 -1.0 0.1 -0.1
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 2.9 0.3 0.4 0.4 0.4 1.7 0.3 0.1 -0.1
Pain experienced in last month 1.4 2.3 3.6 1.5 1.6 1.8 1.4 1.5 1.6 -0.1 -1.9
Supplements: Calcium 0.9 0.9 2.3 -0.8 -1.0 -0.9 -0.9 -0.9 -0.4 -1.0 1.5
Basal cell carcinoma (self-reported) 0.3 0.3 0.9 -0.1 -0.1 -0.3 -0.2 -0.7 1.0 0.8 0.6
Heart attack/myocardial infarction (self-reported) 0.3 0.4 2.3 -0.2 -0.4 -0.4 -0.3 -0.7 -1.5 -0.1 -0.3
Deep venous thrombosis (DVT) (self-reported) 1.2 1.6 5.7 0.9 0.8 0.8 0.7 0.2 -0.6 2.4 2.0
Heart disease (siblings) 0.4 0.4 1.2 0.0 -0.2 -0.2 -0.4 -1.1 -0.3 -1.0 -0.9
Alcohol drinker status: Previous 0.2 0.2 0.8 -0.0 0.0 0.1 0.3 0.5 -0.9 0.6 0.3
Pack years of smoking 0.1 0.2 1.1 -0.4 -0.2 -0.2 -0.3 0.2 -0.4 1.0 0.1
Impedance of whole body 0.1 0.6 1.6 0.7 0.6 0.5 0.5 0.2 1.2 0.6 -1.2
Leg fat mass (left) 1.3 5.1 8.6 -2.4 -2.6 -2.7 -2.5 -2.2 -2.9 -1.0 0.8
Arm predicted mass (left) 0.4 1.8 3.9 -1.2 -1.4 -1.4 -1.4 -1.3 -1.3 -0.1 2.0