Hub : Genes

MAP7

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1460	0.0480	2.2e-05	0.140	NA	0.136	NA	0.144	3.9e-08	NA	6.2e-08	NA	2.5e-08
2	GTEx	Artery Tibial	0.1847	0.0366	1.1e-16	0.284	NA	0.305	NA	0.303	1.7e-22	NA	2.6e-24	NA	4.0e-24
3	GTEx	Esophagus Muscularis	0.1480	0.0430	4.9e-07	0.113	NA	0.133	NA	0.142	2.3e-07	NA	1.8e-08	NA	6.3e-09
4	GTEx	Heart Atrial Appendage	0.0830	0.0390	9.2e-03	0.090	NA	0.074	NA	0.082	7.3e-05	NA	3.3e-04	NA	1.6e-04
5	GTEx	Heart Left Ventricle	0.2135	0.0616	4.1e-07	0.152	NA	0.155	NA	0.159	1.9e-08	NA	1.2e-08	NA	7.9e-09
6	GTEx	Nerve Tibial	0.1039	0.0408	3.0e-04	0.028	NA	0.047	NA	0.089	4.2e-03	NA	2.8e-04	NA	7.8e-07
7	METSIM	Adipose	0.0688	0.0302	1.4e-03	0.027	0.014	0.024	0.020	0.018	5.1e-05	0.0027	1.2e-04	0.00045	7.3e-04
8	YFS	Blood	0.0331	0.0156	1.9e-03	0.007	0.005	0.005	0.006	0.004	2.2e-03	0.0073	5.6e-03	0.00240	1.4e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.1	0.2	1.0	-0.3	-0.1	0.1	-0.1	-0.3	-0.4	0.6	-1.0
Bipolar Disorder or Schizophrenia	0.3	0.8	2.0	-1.0	-1.1	-0.8	-1.1	-1.4	-0.7	-0.4	-0.4
Depressed Affect (Nagel 2018)	0.3	0.6	2.2	-0.2	-0.5	-0.7	-0.5	-0.2	-1.5	-0.2	1.1
Depression (Nagel 2018)	0.1	0.1	0.8	0.1	0.1	0.1	0.3	0.2	-0.4	-0.1	-0.9
Intelligence (Savage-Jansen 2018)	1.2	3.6	8.3	2.9	2.3	2.1	2.2	0.9	1.3	1.7	-0.5
Neuroticism (Nagel 2018)	0.3	0.7	1.2	-0.2	-0.7	-0.9	-0.8	-1.1	-1.1	0.2	1.0
Schizophrenia (2018)	0.6	1.3	2.5	-1.0	-1.3	-1.2	-1.3	-1.6	-1.0	-0.9	0.2
Schizophrenia vs Biploar Disorder	0.7	0.9	4.6	0.1	-0.3	-0.6	-0.5	-0.8	0.4	-1.2	2.1
Worry (Nagel 2018)	0.6	1.3	3.1	-0.9	-1.2	-1.4	-1.4	-1.8	-0.6	-0.6	0.5
Alzheimer’s Disease (in mother)	0.3	0.3	0.9	-0.1	-0.2	-0.0	-0.0	-0.9	-0.8	-0.8	0.8
Alzheimer’s Disease (in father)	0.7	0.8	1.6	-1.3	-1.1	-1.2	-1.2	-0.3	-0.6	-0.2	-0.0
Alzheimer’s Disease (including proxy)	0.1	0.2	0.5	-0.3	-0.2	-0.2	-0.1	-0.4	-0.6	-0.7	0.7
Crohns Disease (2017)	0.3	0.7	4.0	0.3	0.1	0.0	-0.0	-0.4	1.1	-0.7	-2.0
Irritable Bowel Disease (IBD)	0.4	0.9	3.7	0.3	0.3	0.2	0.1	0.6	1.3	-1.2	-1.9
Ulcerative Colitis (UC)	0.2	0.3	1.1	0.0	0.0	0.1	-0.1	1.0	0.3	-0.9	-0.8
Major Depression (MDD)	0.3	0.4	1.7	0.1	0.4	0.6	0.2	0.6	0.3	1.3	-0.4
Reaction Time	0.7	1.4	6.5	0.2	-0.0	-0.1	-0.1	-0.1	-0.3	-2.6	2.1
Verbal and Numeric Reasoning (VNR)	0.8	1.9	4.9	2.2	1.6	1.4	1.6	0.2	1.0	1.4	0.2
Breast Cancer	1.6	3.9	5.4	-2.3	-2.2	-2.2	-2.2	-2.0	-0.8	-2.0	1.6
Ovarian Cancer	1.2	1.6	3.5	-1.4	-1.3	-1.1	-1.1	-0.7	-1.9	-0.6	1.8
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.3	0.5	1.7	-0.1	-0.4	-0.5	-0.7	-1.3	0.8	-0.5	-0.5
Bipolar Disorder (2011)	0.7	0.7	3.3	0.3	0.5	0.6	0.6	0.1	0.5	1.8	-0.9
Body Mass Index (BMI) (2010)	0.3	0.4	1.4	-0.2	-0.3	-0.3	-0.2	-0.9	-0.4	-1.2	-0.4
Coronary Artery Disease (CAD)	0.4	0.5	3.1	0.4	0.5	0.3	0.1	-0.1	1.8	0.1	0.2
Crohns Disease (2012)	0.1	0.2	1.4	-0.0	-0.1	-0.2	-0.2	-0.3	0.1	-0.2	-1.2
Mean Putamen Volume	0.5	0.6	2.0	-0.1	0.0	0.1	0.2	1.4	1.1	-0.0	-1.2
Fasting Glucose	0.5	0.6	3.0	-0.4	-0.5	-0.6	-0.6	-0.3	-0.8	-1.7	0.1
HbA1C	0.3	0.3	0.8	-0.7	-0.7	-0.5	-0.4	-0.4	-0.9	-0.5	-0.2
HDL Cholesterol	0.6	0.9	4.8	0.2	0.1	0.2	0.2	0.1	-0.4	2.2	1.6
LDL Cholesterol	0.5	0.8	2.8	0.5	0.9	0.9	0.7	0.3	1.7	-0.1	-0.9
Lupus	0.5	0.8	2.0	1.0	0.9	0.8	0.8	0.8	1.4	0.8	0.1
Neuroticism (2016)	0.2	0.2	1.1	0.3	0.3	0.2	0.4	0.5	-1.1	0.5	0.1
Primary Biliary Cirrhosis	0.1	0.2	0.5	-0.4	-0.3	-0.4	-0.3	-0.7	0.2	0.2	0.4
Rheumatoid Arthritis	0.4	0.5	1.1	-0.8	-0.9	-1.0	-0.9	-0.6	-0.1	-0.1	0.6
Schizophrenia (2014)	1.2	2.7	4.5	-1.8	-2.1	-1.9	-2.1	-1.5	-1.1	-1.3	0.7
Triglycerides	0.7	1.1	2.1	-1.1	-1.0	-0.9	-1.2	-1.5	-0.8	-1.2	-0.1
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.7	-0.0	-0.0	-0.1	-0.2	-0.8	0.3	0.8	0.1
Ulcerative Colitis	0.2	0.3	0.9	-0.4	-0.4	-0.5	-0.7	0.9	0.3	-0.3	-0.3
Blood Eosinophil Count	0.2	1.4	2.3	1.5	1.4	1.1	1.2	0.4	1.4	0.6	-1.4
Blood Platelet Count	0.9	10.0	37.9	1.6	1.3	1.3	1.7	2.2	-0.5	5.3	6.2
Blood Red Count	0.1	0.8	3.9	1.0	0.5	0.0	0.3	-0.6	-0.6	-0.7	-2.0
Blood White Count	0.3	2.3	6.8	1.7	1.5	1.3	1.6	1.5	-0.3	2.6	-0.5
Heel T-Score	0.5	4.3	7.6	1.7	2.4	2.6	2.5	1.9	2.8	1.2	0.3
BMI	1.0	5.5	7.8	-2.8	-2.7	-2.6	-2.5	-1.8	-2.4	-1.4	2.4
Height	0.0	0.8	5.9	-0.5	0.0	0.4	0.2	0.1	0.1	0.6	2.4
Waist Hip Ratio (WHR)	0.1	0.3	0.7	0.8	0.6	0.3	0.6	0.6	-0.3	0.1	-0.2
Systolic Blood Pressure	0.3	1.5	3.3	-0.9	-1.2	-1.4	-1.3	-1.8	-1.6	-0.1	0.5
Smoking Status	0.2	0.4	1.4	0.8	0.6	0.5	0.5	1.2	0.1	-0.3	0.3
Allergy or Eczema	0.3	0.8	4.1	0.3	0.2	-0.2	-0.2	-0.1	1.3	0.5	-2.0
Cardiovascular Disease	0.1	0.4	1.5	0.7	0.5	0.4	0.6	-0.2	-0.1	-1.2	0.1
Hypothyroidism (self reported)	0.3	0.8	1.9	0.8	0.9	0.6	0.8	1.0	1.4	0.3	0.9
Respiratory disease	1.4	3.1	4.3	-1.6	-1.9	-2.0	-1.8	-1.9	-2.1	0.7	1.7
Type 2 Diabetes (T2D) (2018)	1.5	2.8	3.6	-1.4	-1.9	-1.9	-1.9	-1.7	-1.3	-1.3	1.8
Lung FEV1/FVC ratio	0.3	1.5	2.6	-1.1	-1.4	-1.5	-1.4	-1.6	-0.9	-1.0	-0.1
Lung FVC	2.3	11.8	16.3	3.7	4.0	4.0	4.0	3.5	3.7	2.4	-0.9
Neuroticism	0.1	0.1	0.6	0.2	-0.1	-0.3	-0.1	-0.4	-0.1	-0.8	0.4
Chronotype (morning person)	0.0	0.1	0.4	0.1	0.2	0.3	0.2	-0.6	0.0	-0.6	-0.1
Hair Pigment	0.2	6.0	8.9	2.1	2.5	2.7	2.5	3.0	2.3	1.2	-2.7
Tanning	0.2	2.6	12.9	1.1	1.1	0.9	0.9	1.4	0.8	3.6	1.1
Hand grip strength (left)	0.2	0.5	1.9	-0.8	-0.7	-0.6	-0.7	-0.3	0.2	0.3	1.4
Number of treatments/medications taken	1.5	2.8	10.9	-0.9	-1.5	-1.7	-1.5	-1.3	-1.0	-3.3	0.1
Average weekly spirits intake	0.3	0.4	1.2	0.0	-0.3	-0.4	-0.2	-0.6	-0.6	1.1	0.8
Sensitivity / hurt feelings	0.1	0.1	0.7	0.3	0.3	0.1	0.2	-0.0	-0.2	0.4	0.9
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.7	-0.0	-0.2	-0.4	0.1	-0.3	-0.4	-0.4	-0.8
Hearing difficulty/problems: Yes	1.0	1.5	2.8	1.7	1.5	1.5	1.5	1.0	0.4	1.1	-0.1
Relative age of first facial hair	0.5	1.1	1.7	-1.3	-1.2	-1.1	-1.2	-1.1	-1.0	0.8	-0.1
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.7	1.0	0.6	0.4	0.5	0.0	1.3	1.2	-0.7
Ever used hormone-replacement therapy (HRT)	0.6	0.8	3.0	0.4	0.5	0.6	0.6	0.1	1.4	0.1	-1.7
Ever had hysterectomy (womb removed)	0.4	0.4	1.0	-0.7	-0.6	-0.6	-0.5	-1.0	0.3	0.5	0.7
Systolic blood pressure, automated reading	1.8	5.2	9.2	-2.2	-2.7	-2.8	-2.7	-2.2	-3.0	0.1	0.4
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	2.1	-1.3	-1.1	-0.8	-0.9	-1.0	-1.4	-1.3	1.1
Angina	0.4	0.6	1.2	1.0	0.6	0.4	0.6	0.4	-1.1	1.1	-0.4
Medication for hormone replacement therapy	0.5	0.6	1.7	0.4	0.7	0.6	1.0	1.3	-0.0	-0.4	-0.8
Vitamin and mineral supplements	0.5	0.6	2.0	-0.1	-0.6	-0.8	-0.5	-1.4	-0.7	-1.0	0.5
Supplements: Zinc	2.2	2.4	3.5	-1.9	-1.7	-1.9	-1.8	-1.6	0.1	-1.2	1.3
Medication: Co-codamol	0.3	0.4	1.5	-0.6	-0.3	0.1	-0.2	-0.2	-0.2	1.2	0.9
Medication: Metformin	0.5	0.7	4.1	-0.3	-0.3	-0.2	-0.2	-0.1	-1.2	-0.0	2.0
Diabetes (father)	2.6	3.2	6.2	-2.0	-2.0	-2.1	-1.8	-1.5	-0.8	0.4	2.5
Diabetes (mother)	1.7	2.2	3.3	-1.8	-1.8	-1.7	-1.6	-1.6	-1.6	-0.6	0.2
Severe depression (siblings)	1.5	1.7	5.0	-0.8	-1.2	-1.4	-1.1	-1.2	-2.2	0.2	1.4
Pack years adult smoking proportion	0.2	0.3	2.0	-0.2	-0.1	-0.2	-0.2	0.2	0.1	1.4	0.1
Impedance of leg (right)	0.2	0.8	2.2	0.9	0.8	0.7	0.6	0.4	1.5	1.0	-1.0
Leg fat-free mass (left)	0.3	1.7	3.8	-1.3	-1.3	-1.2	-1.2	-1.1	-1.6	-0.1	1.9
Trunk fat percentage	1.4	5.7	8.8	-2.6	-2.9	-3.0	-2.7	-2.4	-2.7	-1.1	0.6
Hand grip strength (right)	0.2	0.4	1.9	-0.4	-0.3	-0.3	-0.4	-0.3	0.9	-0.5	1.4
Townsend deprivation index at recruitment	0.1	0.1	0.4	0.5	0.3	0.1	0.3	0.1	-0.6	0.1	0.4
Current tobacco smoking	0.1	0.2	1.4	-0.2	0.0	-0.0	0.0	-0.0	-0.1	1.2	0.2
Average weekly fortified wine intake	0.5	0.6	3.2	0.7	0.4	0.4	0.6	-0.4	0.1	0.6	-1.8
Maternal smoking around birth	0.8	1.2	4.8	0.9	0.9	0.9	1.1	0.9	-0.5	2.2	-0.3
Fed-up feelings	0.3	0.5	2.1	0.3	0.1	-0.0	0.2	0.3	-1.1	-1.4	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.8	-0.1	-0.1	-0.1	0.1	0.1	-0.9	-0.9	-0.8
Relative age voice broke	0.1	0.2	1.0	0.1	0.3	0.1	0.2	-0.5	0.0	1.0	-0.1
Taking other prescription medications	2.7	4.1	6.9	-1.9	-2.5	-2.6	-2.4	-2.4	-1.2	-1.1	1.6
Age when periods started (menarche)	0.1	0.3	0.7	0.4	0.1	0.0	-0.1	-0.4	0.7	0.8	0.8
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.7	-0.8	-0.5	-0.6	-0.6	-1.3	0.3	0.3	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	2.2	-0.4	-0.1	0.2	-0.0	0.2	-0.5	1.5	-0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	-0.5	-0.1	-0.1	-0.2	0.0	0.0	0.5	0.1
Qualifications: CSEs or equivalent	0.5	0.6	1.5	1.0	0.7	0.4	0.5	0.4	1.2	-1.2	-0.0
Serious illness, injury or assault to yourself	0.8	1.0	3.5	-0.5	-0.8	-1.0	-0.9	-1.1	-0.1	0.7	1.9
High blood pressure	0.8	2.2	4.7	-1.1	-1.5	-1.6	-1.3	-1.8	-2.2	-1.2	0.6
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.8	-0.4	-0.4	-0.6	-0.3	-0.5	0.0	0.2	-1.3
Multivitamins +/- minerals	0.5	0.6	2.7	-0.3	0.3	0.7	0.3	1.6	0.9	0.7	-0.1
Stomach or abdominal pain in last month	0.8	1.0	1.7	-0.9	-1.0	-1.2	-1.2	-1.3	-0.2	0.3	1.3
Supplements: Glucosamine	0.4	0.5	1.5	0.7	0.7	0.7	0.7	0.2	1.2	0.8	-0.3
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	8.2	0.6	0.2	0.2	0.3	0.4	-0.7	1.1	2.9
Medication: Atenolol	1.0	1.3	1.9	-1.4	-1.2	-1.1	-1.3	-1.3	-1.1	-0.4	0.9
Medication: Levothyroxine sodium	1.8	3.0	5.4	-1.9	-2.1	-2.3	-2.1	-1.4	-1.3	0.4	1.6
Sitting height	0.2	1.4	3.1	1.4	1.4	1.2	1.1	0.8	1.8	0.0	0.9
Chronic bronchitis/emphysema (father)	0.4	0.5	1.0	-1.0	-0.8	-0.7	-0.9	-0.6	-0.5	-0.3	0.3
High blood pressure (mother)	0.6	0.8	1.8	-0.7	-0.9	-1.3	-1.1	-1.3	0.6	-0.3	-0.7
Body mass index (BMI)	1.1	4.8	7.5	-2.3	-2.5	-2.6	-2.3	-2.1	-2.7	-1.3	1.0
Impedance of leg (left)	0.2	1.0	2.6	0.9	0.8	0.8	0.7	0.3	1.6	0.8	-1.4
Leg predicted mass (left)	0.3	1.7	3.3	-1.3	-1.3	-1.3	-1.2	-1.2	-1.6	-0.1	1.8
Trunk fat mass	1.4	6.1	8.8	-2.7	-2.9	-3.0	-2.8	-2.4	-2.9	-1.0	1.2
Waist circumference	0.8	2.8	6.1	-1.6	-1.9	-2.0	-1.6	-1.4	-2.5	-0.6	1.2
Number of incorrect matches in round	3.7	6.1	8.6	-2.5	-2.6	-2.5	-2.8	-2.7	-2.9	-2.0	1.4
Past tobacco smoking	0.3	0.5	1.6	-0.9	-0.5	-0.4	-0.5	-0.9	0.0	1.2	-0.2
Alcohol usually taken with meals	1.0	1.6	3.5	0.9	1.5	1.5	1.5	1.3	1.9	-0.3	0.6
Nervous feelings	0.3	0.6	2.6	0.6	0.2	0.0	0.1	-0.5	0.4	-1.3	-1.6
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.7	0.5	0.4	0.3	0.4	-0.1	-0.1	-0.7	-1.6
Hearing difficulty/problems with background noise	0.2	0.4	0.9	-0.1	-0.5	-0.8	-0.6	-0.9	0.2	-0.9	0.4
Hair/balding pattern: Pattern 2	0.8	1.0	6.7	-0.4	-0.6	-0.6	-0.6	-0.4	0.5	0.3	2.6
Had menopause	0.1	0.1	0.2	-0.1	-0.2	-0.2	-0.3	-0.1	-0.5	-0.3	-0.0
Had other major operations	0.4	0.5	2.4	0.2	0.5	0.6	0.6	1.5	0.2	0.7	0.7
Forced vital capacity (FVC)	2.6	10.1	14.8	3.5	3.9	3.8	3.7	3.1	3.6	1.6	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.2	-0.0	0.2	0.4	0.2	0.3	-0.1	0.3	-0.4
Ever unenthusiastic/disinterested for a whole week	2.2	2.7	4.1	-1.3	-1.7	-1.8	-1.7	-1.9	-1.8	-2.0	-0.7
Qualifications: None of the above	3.4	7.2	10.1	-3.2	-3.1	-3.2	-3.2	-2.5	-2.6	-2.0	1.1
Financial difficulties in last 2 years	0.7	0.9	1.9	-1.3	-1.2	-1.0	-0.8	-0.7	-1.4	-0.6	-0.0
Mouth/teeth dental problems	0.1	0.1	0.4	0.3	0.3	0.3	0.2	-0.4	-0.3	0.6	0.2
Heart attack	0.4	0.5	2.7	-0.1	-0.3	-0.4	-0.3	-0.7	-1.7	-0.1	-0.5
Allergy	0.1	0.2	1.0	0.2	0.3	0.4	0.2	0.5	0.1	-1.0	0.3
Pain all over the body in last month	1.4	1.5	4.9	-1.2	-1.4	-1.2	-1.1	0.1	-2.2	-0.9	0.7
Diabetes (self-reported)	1.6	2.4	3.5	-1.2	-1.6	-1.7	-1.5	-1.9	-1.3	-1.3	1.8
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.6	-0.6	-0.5	-0.5	-0.6	-0.8	0.2	-0.6	-0.5
Medication: Ramipril	1.2	1.5	6.4	0.2	-0.6	-1.1	-0.8	-1.0	-1.2	-2.5	1.1
Medication: Simvastatin	0.2	0.3	0.6	0.7	0.6	0.6	0.6	0.1	-0.2	0.4	-0.6
Fluid intelligence score	1.5	3.0	5.9	2.4	2.1	1.9	2.1	0.4	1.7	1.5	-0.6
Illnesses of siblings	1.5	2.1	4.2	1.9	1.5	1.2	1.4	1.2	2.0	1.4	0.4
Neuroticism score	0.1	0.3	2.1	0.3	0.1	-0.0	0.2	-0.4	-0.2	-1.5	0.1
Weight	1.1	5.2	7.3	-2.3	-2.5	-2.5	-2.4	-2.3	-2.7	-0.8	2.1
Impedance of arm (right)	0.1	0.4	0.8	0.9	0.7	0.5	0.7	0.3	0.9	0.7	-0.4
Arm fat percentage (right)	1.3	5.1	9.2	-2.2	-2.6	-2.8	-2.4	-2.2	-3.0	-1.2	0.6
Trunk fat-free mass	0.2	1.2	5.3	-0.8	-0.8	-0.7	-0.8	-0.9	-1.2	0.1	2.3
Hip circumference	1.1	4.6	6.4	-2.2	-2.4	-2.5	-2.4	-2.2	-2.3	-1.3	1.6
Time employed in main current job	1.4	1.6	4.1	0.8	1.1	1.1	1.1	1.0	1.4	-1.2	-2.0
Alcohol intake versus 10 years previously	0.3	0.5	0.9	0.9	0.8	0.7	0.6	0.0	0.8	0.4	0.9
Father’s age at death	0.1	0.2	0.4	0.4	0.5	0.5	0.6	0.1	-0.3	-0.0	0.5
Worrier / anxious feelings	0.2	0.5	1.1	-0.4	-0.6	-0.6	-0.6	-1.1	-0.5	-0.9	-0.6
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.7	2.8	-1.7	-1.6	-1.4	-1.3	-1.1	-1.1	-1.6	-0.0
Falls in the last year	0.2	0.3	1.0	-0.0	-0.4	-0.5	-0.1	1.0	-0.5	-0.3	0.6
Hair/balding pattern: Pattern 3	1.3	2.0	4.4	1.0	1.5	1.9	1.5	1.5	0.6	-0.3	-2.1
Number of live births	0.6	0.9	1.7	-1.2	-1.2	-1.3	-1.1	-0.8	-0.3	-0.3	0.6
Forced expiratory volume in 1-second (FEV1)	1.7	5.6	9.1	2.6	2.8	2.8	2.7	2.2	3.0	1.0	-0.7
Pulse rate	1.7	2.9	3.9	1.8	1.8	1.9	1.9	2.0	0.3	1.6	-1.6
Happiness	0.5	0.7	4.3	-0.4	-0.3	-0.3	-0.3	0.6	0.1	0.1	-2.1
Noisy workplace	0.4	0.5	1.3	0.7	0.7	0.6	0.7	1.2	0.9	0.0	-0.5
Qualifications: A levels/AS levels or equivalent	0.6	1.3	3.4	1.9	1.3	0.8	1.0	0.2	1.8	0.1	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.7	0.4	-0.0	-0.3	0.0	-0.5	-0.1	0.7	0.8
Mouth/teeth dental problems: Dentures	0.2	0.3	0.6	-0.8	-0.7	-0.7	-0.6	0.3	-0.5	-0.1	-0.1
Asthma	1.1	2.3	3.1	-1.5	-1.8	-1.8	-1.6	-1.6	-1.5	0.8	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	3.8	-0.2	0.1	0.4	0.3	1.1	0.2	-0.1	-1.9
Medication: Cholesterol lowering	0.2	0.3	1.5	0.5	0.2	0.1	0.1	-0.1	-1.2	0.1	0.6
Depression (self-reported)	0.2	0.2	0.9	0.7	0.3	-0.0	0.1	-0.2	0.9	-0.5	-0.4
Medication: Lansoprazole	1.2	1.4	3.3	-0.8	-1.2	-1.3	-1.4	-1.8	-0.2	-0.9	-1.2
Prospective memory result	0.4	0.5	2.9	-0.5	-0.3	-0.2	-0.2	-0.2	0.0	-1.7	-0.7
Lung cancer (father)	0.8	0.9	4.3	-0.9	-0.7	-0.6	-0.7	-0.7	-0.4	-2.1	-0.0
Illnesses of mother	1.1	1.4	3.0	1.0	1.3	1.4	1.3	1.7	0.8	0.6	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.9	5.9	9.1	2.6	3.0	3.0	2.9	2.3	2.8	0.9	-0.4
Pulse wave Arterial Stiffness index	0.4	0.5	0.9	-0.7	-0.7	-0.8	-0.7	-1.0	-0.8	-0.3	0.3
Impedance of arm (left)	0.0	0.2	0.7	0.4	0.3	0.3	0.4	0.0	0.7	0.8	-0.3
Arm fat mass (right)	1.2	5.1	8.0	-2.3	-2.6	-2.7	-2.4	-2.3	-2.8	-0.9	1.3
Trunk predicted mass	0.2	1.3	5.4	-0.8	-0.8	-0.7	-0.8	-0.9	-1.2	0.1	2.3
Standing height	0.1	0.9	6.3	-0.4	-0.3	-0.2	-0.4	-0.6	-0.1	0.6	2.5
Length of working week for main job	0.4	0.4	1.4	0.4	0.4	0.2	0.3	-0.4	1.2	-0.6	-1.1
Exposure to tobacco smoke at home	1.2	1.3	2.3	-1.5	-1.4	-1.4	-1.5	-0.9	-0.4	-0.1	-1.0
Breastfed as a baby	2.7	3.3	6.5	-2.6	-2.0	-1.9	-2.2	-2.5	-1.1	-0.2	0.4
Tense / ‘highly strung’	0.5	0.8	1.6	-1.1	-0.9	-0.8	-0.7	-1.3	-0.8	-0.8	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.6	4.0	6.4	-2.4	-2.3	-2.3	-2.4	-2.5	-1.1	-1.0	0.6
Hair/balding pattern: Pattern 4	0.2	0.5	0.8	0.7	0.8	0.7	0.8	-0.1	0.9	0.4	0.9
Birth weight of first child	0.5	1.0	2.7	-1.6	-1.2	-0.9	-1.1	-1.0	-0.6	-0.6	0.0
Peak expiratory flow (PEF)	1.7	4.1	5.9	2.0	2.3	2.4	2.3	2.4	1.9	1.3	-0.8
Pulse wave reflection index	1.4	1.8	2.8	-1.2	-1.4	-1.4	-1.5	-1.7	-1.6	-0.9	0.8
Ever highly irritable/argumentative for 2 days	1.6	1.9	4.5	-1.6	-1.5	-1.3	-1.2	-1.1	-2.1	0.7	1.0
Loud music exposure frequency	0.5	0.5	3.2	0.1	0.1	0.1	0.1	-0.1	0.6	-1.8	-0.6
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.3	1.1	0.5	0.2	0.4	0.0	0.5	0.9	0.4
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.6	-0.6	-0.7	-0.8	-0.7	-0.4	0.1	-0.3	0.5
Blood clot in the leg (DVT)	1.2	1.5	4.6	1.0	0.9	0.8	0.8	0.2	-0.5	2.2	2.0
Medication: Paracetamol	0.3	0.6	2.6	-0.1	0.2	0.3	0.1	0.3	1.0	0.8	-1.6
Headache pain in last month	1.7	2.8	7.9	-1.2	-1.7	-1.9	-1.6	-1.8	-2.8	-0.8	0.3
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.6	-0.0	0.3	0.4	0.3	0.5	1.6	1.4	-0.6
Glaucoma (self-reported)	0.0	0.1	0.2	0.1	0.1	0.2	0.1	0.1	0.2	0.4	-0.4
Gout (self-reported)	3.2	4.4	9.0	-3.0	-2.8	-2.5	-2.8	-1.8	-0.8	-0.1	-0.0
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.5	-0.2	-0.4	-0.7	-0.4	-0.1	0.3	0.4	0.5
Medication: Amlodipine	0.4	0.5	2.3	-0.0	-0.3	-0.3	-0.3	-0.7	0.3	-1.5	-0.9
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.9	0.7	0.1	-0.4	-0.3	-0.7	0.4	0.6	0.9
Birth weight	0.3	0.6	2.6	0.2	-0.1	-0.1	-0.1	-1.3	-0.2	-1.6	-0.2
Chronic bronchitis/emphysema (mother)	0.8	1.0	1.4	-1.0	-1.0	-0.9	-1.0	-1.2	-0.9	-0.9	0.9
High blood pressure (siblings)	2.3	3.3	5.0	-2.2	-2.1	-2.0	-2.1	-1.6	-2.2	-1.2	-0.6
Forced vital capacity (FVC), Best measure	1.8	6.6	10.6	2.7	3.2	3.3	3.0	2.5	2.8	1.3	-0.3
Body fat percentage	1.5	6.0	9.1	-2.6	-2.9	-3.0	-2.7	-2.4	-3.0	-1.0	0.6
Leg fat percentage (right)	1.8	6.6	10.3	-2.6	-3.0	-3.1	-2.9	-2.7	-3.2	-1.2	0.4
Arm fat-free mass (right)	0.2	1.2	2.7	-1.2	-1.1	-0.9	-1.1	-0.9	-1.1	0.4	1.6
Exposure to tobacco smoke outside home	0.5	0.7	3.4	0.7	0.1	-0.1	0.3	0.5	-1.8	-0.2	1.1
Comparative body size at age 10	0.4	1.0	2.3	1.5	1.2	1.0	1.1	0.4	1.2	-0.6	0.0
Number of full brothers	0.6	0.7	2.9	-0.5	-0.3	-0.3	-0.5	-0.1	1.4	-0.3	-1.7
Worry too long after embarrassment	0.6	1.0	1.9	1.4	1.2	1.1	1.2	-0.2	1.4	-0.3	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.4	-0.4	-0.6	-0.7	-0.6	-1.0	-0.2	0.6	1.6
Wheeze or whistling in the chest in last year	1.0	1.8	2.9	-1.4	-1.5	-1.4	-1.2	-1.1	-1.7	-0.1	-1.7
Number of children fathered	0.3	0.4	1.6	-0.5	-0.2	-0.1	-0.1	0.5	-1.3	0.6	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.8	0.5	0.6	0.7	0.7	1.3	1.3	1.2	0.1
Age at first live birth	0.5	1.0	1.7	1.2	1.0	0.9	0.9	0.4	1.3	1.3	-0.2
Pulse wave peak to peak time	0.3	0.3	0.7	0.6	0.6	0.7	0.6	0.9	0.5	0.4	-0.1
Health satisfaction	0.4	0.5	2.5	0.6	0.3	0.2	0.5	0.7	-0.0	0.1	-1.6
Shortness of breath walking on level ground	0.2	0.2	0.5	0.7	-0.1	-0.6	-0.1	-0.0	0.0	0.6	0.5
Qualifications: College or University degree	0.9	2.8	4.5	2.1	2.0	1.9	1.9	1.4	1.5	-0.5	-1.3
Eye problems/disorders: None of the above	0.6	0.6	1.7	1.1	0.9	0.7	0.8	0.5	0.1	1.3	0.2
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.6	0.7	0.1	-0.2	0.2	-0.4	-0.6	-0.3	0.8
Emphysema/chronic bronchitis	0.8	0.9	5.9	-0.1	-0.3	-0.4	-0.5	-0.4	-0.8	0.5	2.4
Medication for pain relief, constipation, heartburn	0.4	0.6	2.2	-0.2	-0.2	-0.2	-0.2	-1.5	-0.7	-1.0	1.0
Neck or shoulder pain in last month	0.8	1.2	2.1	-1.4	-1.3	-1.3	-1.3	-1.1	-0.2	0.4	0.8
Medication: Blood pressure	0.6	1.1	3.3	-0.2	-0.5	-0.6	-0.5	-1.1	-1.7	-1.8	0.4
Angina (self-reported)	0.4	0.5	1.5	0.9	0.4	0.2	0.5	0.2	-1.0	1.2	-0.4
Migraine (self-reported)	0.1	0.2	0.9	-0.2	-0.1	0.2	0.1	0.2	-1.0	0.1	-0.5
Medication: Ibuprofen	0.7	0.8	3.9	0.0	0.1	0.4	0.4	1.0	-0.3	-1.1	-2.0
Medication: Allopurinol	1.2	1.6	3.4	-1.8	-1.6	-1.3	-1.6	-0.9	-0.1	1.1	0.6
Medication: Omeprazole	0.8	1.0	4.4	0.7	0.8	0.8	0.9	2.1	0.5	0.9	-0.0
Medication: Seretide 50 evohaler	0.5	0.6	1.5	-0.9	-0.8	-0.6	-0.8	-1.2	-0.2	-0.2	1.0
Mean time to correctly identify matches	0.9	1.7	7.4	-0.3	-0.6	-0.6	-0.6	-0.6	-0.9	-2.7	1.9
Heart disease (mother)	0.5	0.6	1.1	-0.5	-0.8	-1.0	-0.8	-0.9	-0.6	-0.6	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	2.5	-1.6	-1.4	-1.5	-1.4	-0.7	0.5	-1.0	0.9
Whole body fat mass	1.2	5.2	8.5	-2.4	-2.7	-2.7	-2.5	-2.1	-2.9	-0.8	1.1
Leg fat mass (right)	1.5	5.7	9.0	-2.5	-2.8	-2.9	-2.6	-2.3	-3.0	-1.0	1.1
Arm predicted mass (right)	0.3	1.3	2.7	-1.2	-1.1	-1.0	-1.1	-1.1	-1.3	0.1	1.6
Pulse rate, automated reading	0.1	0.3	1.5	0.2	0.2	0.4	0.5	0.4	-1.2	-0.6	0.2
Alcohol intake frequency.	0.1	0.3	1.9	-0.2	-0.3	-0.3	-0.1	-0.2	-1.4	-0.3	-0.4
Comparative height size at age 10	0.1	0.8	2.2	-0.3	-0.4	-0.5	-0.5	-0.3	-1.4	1.1	1.5
Number of full sisters	0.5	0.6	1.0	0.8	0.8	0.8	0.9	1.0	-0.4	-0.7	0.7
Suffer from ‘nerves’	0.4	0.7	1.3	-0.8	-1.0	-1.0	-0.9	-1.1	-0.6	-0.7	-0.3
Overall health rating	0.1	0.2	0.9	-0.5	-0.7	-0.9	-0.5	-0.2	-0.0	0.0	0.3
Chest pain or discomfort	1.5	2.2	3.9	-1.6	-1.8	-1.9	-1.7	-2.0	-1.1	0.3	-0.4
Had major operations	0.4	0.4	0.9	0.9	0.8	0.7	0.6	0.0	0.5	0.3	-1.0
Age at last live birth	1.0	1.5	2.8	1.5	1.3	1.2	1.2	0.8	1.7	1.1	-0.5
Family relationship satisfaction	0.6	0.7	2.9	-0.4	-0.7	-0.6	-0.6	-1.1	0.3	-1.7	-0.4
Leg pain on walking	0.4	0.5	2.4	0.5	0.0	-0.5	0.0	0.4	0.3	1.6	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.9	-0.3	-0.0	0.0	0.1	0.2	-0.3	0.9	0.6
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.8	-0.5	-0.4	-0.2	-0.2	-0.4	-1.1	0.2	1.7
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.0	0.6	0.4	0.2	0.2	0.2	1.0	0.5	0.9
Medication: Aspirin	1.7	2.2	4.5	1.9	1.6	1.3	1.5	2.1	0.8	0.2	-1.3
Supplements: Vitamin C	0.1	0.2	0.6	0.0	-0.2	-0.4	-0.2	-0.3	-0.4	-0.8	0.4
Knee pain experienced in last month	2.3	3.6	5.9	-2.1	-2.2	-2.1	-2.0	-2.4	-1.5	-0.2	1.8
Hypertension (Self-reported)	0.7	1.9	3.4	-1.1	-1.4	-1.6	-1.3	-1.8	-1.9	-1.0	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	3.1	-0.7	-0.8	-0.7	-0.6	-0.5	-0.6	-1.8	-1.3
Illnesses of father: Heart disease	0.7	0.9	1.9	-0.9	-0.9	-0.7	-0.6	-1.3	-1.4	0.6	1.0
Illnesses of siblings: Diabetes	0.6	0.8	1.5	-0.8	-0.9	-1.0	-0.8	-0.6	-0.8	-0.8	-1.2
Smoking status: Previous	0.3	0.5	2.4	0.7	0.2	0.1	0.2	1.1	-0.2	-1.6	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	5.8	1.1	1.3	1.5	1.4	1.2	1.6	-0.8	-2.4
Whole body fat-free mass	0.2	1.4	4.2	-1.1	-1.0	-0.9	-1.0	-1.0	-1.4	0.0	2.0
Leg fat-free mass (right)	0.3	1.6	3.1	-1.2	-1.2	-1.2	-1.1	-1.2	-1.5	-0.2	1.8
Arm fat percentage (left)	1.4	5.5	9.7	-2.4	-2.7	-2.9	-2.5	-2.3	-3.1	-0.9	0.7
Average weekly red wine intake	1.6	2.3	4.1	1.9	2.0	1.9	2.0	1.4	0.5	0.9	-0.5
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.9	0.2	0.1	0.0	0.2	-0.3	-0.2	0.9	-0.6
Mood swings	0.4	0.8	2.1	1.2	0.9	0.7	0.9	1.4	0.8	-0.2	0.3
Loneliness, isolation	0.2	0.3	1.9	0.3	0.2	0.0	0.4	-0.2	-1.4	0.5	0.3
Long-standing illness, disability or infirmity	0.6	0.9	2.0	-0.6	-1.1	-1.4	-1.0	-1.0	-0.9	-0.8	0.7
Ever had bowel cancer screening	0.4	0.5	1.4	-1.0	-0.7	-0.6	-0.7	-0.1	-0.4	0.5	1.2
Diabetes diagnosed by doctor	2.9	4.8	5.2	-2.0	-2.3	-2.3	-2.2	-2.3	-2.0	-2.2	2.1
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.3	-0.3	-0.5	-0.4	-0.2	-0.5	-1.2	0.8	-0.2
Friendships satisfaction	0.3	0.4	1.5	1.2	0.7	0.5	0.8	-0.2	0.3	-0.6	-0.2
Qualifications: nursing, teaching	0.3	0.5	1.4	1.2	0.8	0.4	0.7	0.2	0.9	0.1	-0.5
Commuting to job workplace: Walk	0.8	0.8	3.4	0.3	-0.1	-0.5	-0.3	-1.2	1.1	-0.2	-1.9
Eye problems/disorders: Cataract	1.1	1.3	6.2	-0.7	-0.7	-0.7	-0.9	-0.5	-0.3	-2.5	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.0	-1.4	-1.1	-0.8	-0.9	0.0	-0.4	-0.7	-0.5
Medication for cholesterol	0.8	1.3	1.7	1.2	1.2	1.2	1.0	1.3	1.2	1.2	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	1.7	-1.0	-1.1	-1.3	-1.1	-1.2	-0.4	0.3	0.1
Back pain experienced in last month	0.5	0.8	1.7	0.5	0.7	0.9	0.9	1.0	0.3	1.3	1.1
Mineral and other dietary supplements	1.3	1.7	6.7	-1.1	-1.2	-1.2	-0.9	-1.1	-2.6	-0.3	0.9
Breast cancer (self-reported)	3.1	3.7	5.8	2.0	2.1	2.0	2.0	1.9	1.6	2.4	-0.5
Asthma (self-reported)	1.2	2.4	3.3	-1.5	-1.8	-1.8	-1.6	-1.7	-1.5	0.9	1.3
Osteoporosis (self-reported)	0.4	0.5	1.3	0.0	-0.6	-1.1	-0.9	-0.8	-0.4	-0.4	0.9
Osteoarthritis (self-reported)	1.1	1.4	2.9	-1.4	-1.3	-1.0	-1.2	-1.2	-1.7	0.7	-0.1
Medication: Aspirin	1.3	1.7	3.6	1.7	1.4	1.1	1.3	1.9	0.7	0.1	-1.2
Medication: Gliclazide	1.8	2.0	5.8	-1.0	-1.2	-1.2	-1.0	-0.6	-1.8	-1.3	2.4
Illnesses of father: None of the above (group 1)	1.2	1.5	3.3	1.8	1.4	1.0	1.2	1.4	1.2	0.6	0.6
Smoking status: Current	0.1	0.1	0.8	-0.2	-0.1	-0.2	-0.1	-0.3	-0.1	0.9	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.0	0.5	0.9	0.9	0.8	0.4	1.0	0.2	0.6
Whole body water mass	0.2	1.2	4.2	-0.9	-0.9	-0.8	-0.8	-1.0	-1.3	0.1	2.1
Leg predicted mass (right)	0.3	1.5	2.9	-1.2	-1.2	-1.2	-1.1	-1.1	-1.4	-0.1	1.7
Arm fat mass (left)	1.1	4.6	7.2	-2.2	-2.5	-2.6	-2.3	-2.1	-2.7	-0.7	1.3
Number of self-reported non-cancer illnesses	0.6	1.0	1.8	-0.7	-1.2	-1.3	-1.0	-1.3	-1.1	-0.9	0.2
Average weekly champagne plus white wine intake	1.2	1.7	4.1	2.0	1.7	1.5	1.6	0.0	1.2	-0.2	-0.0
Miserableness	0.2	0.3	0.9	0.6	0.4	0.3	0.5	1.0	-0.5	0.1	0.4
Guilty feelings	0.2	0.4	1.1	0.3	-0.1	-0.3	-0.1	-0.9	-0.8	-0.5	1.1
Wears glasses or contact lenses	1.0	1.1	2.8	-1.2	-0.9	-0.5	-0.8	-1.0	-1.2	-1.0	1.7
Ever taken oral contraceptive pill	0.9	1.0	3.1	-0.9	-1.0	-1.0	-1.0	-1.8	-0.6	-0.7	0.5
Hearing aid user	0.6	0.7	2.1	1.0	0.5	0.5	0.6	0.7	-0.8	-0.7	1.5
Mother’s age at death	0.2	0.3	1.1	0.5	0.5	0.4	0.3	0.1	1.0	-0.6	0.0
Financial situation satisfaction	0.7	0.8	1.7	1.2	0.7	0.2	0.5	0.6	1.3	-0.9	-1.3
Tinnitus: Yes, now most or all of the time	0.6	0.7	4.2	-0.2	0.2	0.3	-0.0	0.4	2.0	0.1	1.1
Commuting to job workplace: Public transport	1.3	1.6	2.7	1.2	1.3	1.5	1.5	1.6	-0.2	1.3	-0.6
Eye problems/disorders: Glaucoma	0.2	0.2	0.5	-0.7	-0.5	-0.4	-0.6	-0.2	-0.0	0.2	0.5
Medication: Blood pressure	0.3	0.6	1.8	-0.5	-0.8	-0.8	-0.8	-1.3	-0.3	0.1	1.0
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.5	0.2	0.5	0.7	0.6	0.5	0.4	0.7	0.3
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.9	0.3	0.5	0.6	0.3	1.0	1.4	0.4	-0.1
High cholesterol (Self-reported)	0.7	1.3	2.5	-0.9	-1.0	-0.9	-0.9	-1.2	-1.3	-1.6	1.3
Medication: Bendroflumethiazide	0.2	0.4	1.1	0.0	-0.2	-0.2	-0.2	-0.7	-0.9	-0.7	-1.0
Medication: Paracetamol	0.6	1.0	4.1	0.5	0.7	0.7	0.7	0.6	1.1	0.6	-2.0
Medication: Lisinopril	1.1	1.4	2.9	-0.9	-0.7	-0.6	-0.7	-1.5	-1.7	-0.8	1.7
Medication: Atorvastatin	0.2	0.3	0.8	-0.3	-0.4	-0.5	-0.4	-0.2	-0.6	-0.9	0.7
Illnesses of father: High blood pressure	1.6	2.0	3.3	-1.6	-1.5	-1.5	-1.5	-1.8	-0.4	-1.8	0.1
Alcohol drinker status: Never	1.0	1.2	3.0	-1.3	-1.3	-0.9	-1.0	-0.8	-1.7	-0.9	0.4
Ever smoked	0.3	0.5	1.4	0.7	0.5	0.5	0.6	0.8	0.3	-1.2	-0.4
Basal metabolic rate	0.4	2.2	4.2	-1.4	-1.5	-1.4	-1.4	-1.4	-1.7	-0.2	2.1
Leg fat percentage (left)	1.7	6.0	9.5	-2.5	-2.8	-2.9	-2.7	-2.7	-3.1	-1.3	0.0
Arm fat-free mass (left)	0.2	0.9	2.7	-0.9	-0.9	-0.9	-1.0	-0.9	-0.9	-0.0	1.6
Number of operations (self-reported)	0.1	0.2	0.7	-0.1	0.3	0.3	0.3	0.2	0.7	0.8	-0.1
Average weekly beer plus cider intake	0.7	1.1	4.2	1.0	0.8	0.7	0.8	1.1	0.5	0.3	-2.0
Irritability	0.1	0.1	0.4	0.2	0.3	0.3	0.4	0.2	0.4	-0.6	-0.1
Risk taking	0.2	0.3	1.1	-0.1	0.3	0.3	0.3	0.9	0.4	-1.1	0.0
Ever had prostate specific antigen (PSA) test	0.4	0.5	1.8	-0.2	-0.2	-0.4	-0.2	-0.9	0.3	1.0	1.3
Fractured/broken bones in last 5 years	0.5	0.7	2.1	0.7	0.6	0.6	0.6	1.0	0.8	0.3	-1.5
Age started oral contraceptive pill	0.6	0.7	2.8	-0.8	-0.9	-0.8	-0.9	-1.7	0.2	-0.3	0.2
Diastolic blood pressure, automated reading	0.3	1.0	2.2	-0.7	-1.0	-1.0	-1.0	-1.3	-1.5	-0.0	-0.8
Ever depressed for a whole week	0.1	0.1	0.4	0.1	-0.2	-0.2	-0.0	-0.4	-0.3	-0.5	-0.6
Unable to work because of sickness or disability	1.7	2.2	3.8	-1.9	-2.0	-1.9	-1.7	-1.0	-1.3	0.2	1.1
Commuting to job workplace: Cycle	0.3	0.3	0.8	0.3	0.4	0.5	0.4	0.1	0.9	-0.9	-0.7
Myopia	1.0	1.4	7.5	-1.1	-1.1	-0.6	-0.8	-0.6	-2.7	-0.4	-0.3
Vascular/heart problems diagnosed by doctor	0.6	1.6	4.6	0.7	1.2	1.2	0.9	1.4	2.2	0.9	-1.1
Cholesterol lowering medication	0.5	0.7	1.2	-1.1	-0.9	-0.8	-0.7	-1.1	-1.0	0.1	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.9	0.3	0.4	0.4	0.4	1.7	0.3	0.1	-0.1
Pain experienced in last month	1.4	2.3	3.6	1.5	1.6	1.8	1.4	1.5	1.6	-0.1	-1.9
Supplements: Calcium	0.9	0.9	2.3	-0.8	-1.0	-0.9	-0.9	-0.9	-0.4	-1.0	1.5
Basal cell carcinoma (self-reported)	0.3	0.3	0.9	-0.1	-0.1	-0.3	-0.2	-0.7	1.0	0.8	0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.3	-0.2	-0.4	-0.4	-0.3	-0.7	-1.5	-0.1	-0.3
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	5.7	0.9	0.8	0.8	0.7	0.2	-0.6	2.4	2.0
Heart disease (siblings)	0.4	0.4	1.2	0.0	-0.2	-0.2	-0.4	-1.1	-0.3	-1.0	-0.9
Alcohol drinker status: Previous	0.2	0.2	0.8	-0.0	0.0	0.1	0.3	0.5	-0.9	0.6	0.3
Pack years of smoking	0.1	0.2	1.1	-0.4	-0.2	-0.2	-0.3	0.2	-0.4	1.0	0.1
Impedance of whole body	0.1	0.6	1.6	0.7	0.6	0.5	0.5	0.2	1.2	0.6	-1.2
Leg fat mass (left)	1.3	5.1	8.6	-2.4	-2.6	-2.7	-2.5	-2.2	-2.9	-1.0	0.8
Arm predicted mass (left)	0.4	1.8	3.9	-1.2	-1.4	-1.4	-1.4	-1.3	-1.3	-0.1	2.0