Hub : Genes

MAPK8IP2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Breast Mammary Tissue 0.1290 0.0540 3.8e-03 0.113 NA 0.071 NA 0.078 2.1e-06 NA 1.6e-04 NA 8.3e-05
2 GTEx Breast Mammary Tissue (Male) 0.1068 0.0850 1.4e-01 -0.010 NA 0.004 NA -0.009 6.2e-01 NA 2.5e-01 NA 5.7e-01
3 GTEx Breast Mammary Tissue (Female) 0.2053 0.0924 1.2e-02 0.019 NA 0.004 NA 0.042 8.5e-02 NA 2.4e-01 NA 2.1e-02
4 GTEx Lung 0.1040 0.0487 5.7e-03 0.059 NA 0.017 NA 0.026 2.7e-05 NA 1.8e-02 NA 3.9e-03
5 GTEx Skin Sun Exposed Lower leg 0.2100 0.0540 4.5e-05 0.164 NA 0.075 NA 0.150 1.5e-13 NA 8.9e-07 NA 2.1e-12
6 GTEx Spleen 0.2350 0.0910 6.6e-03 -0.009 NA 0.051 NA 0.006 6.6e-01 NA 2.0e-02 NA 2.2e-01
7 METSIM Adipose 0.0349 0.0166 1.2e-02 0.003 0.009 0.013 0.008 0.002 1.1e-01 1.5e-02 3.9e-03 0.016 1.6e-01
8 TCGA Kidney Renal Clear Cell Carcinoma 0.0682 0.0304 4.5e-04 0.019 0.034 0.024 NA 0.024 2.8e-03 8.9e-05 9.6e-04 NA 8.9e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.4 0.7 2.3 0.2 0.0 0.8 1.0 0.7 1.1 0.1 -1.5
Bipolar Disorder or Schizophrenia 1.2 3.0 7.2 0.8 0.0 2.0 2.7 -0.9 2.1 0.7 -2.5
Depressed Affect (Nagel 2018) 0.5 1.1 5.2 -0.1 0.0 -0.7 0.8 -1.2 -1.1 -0.0 -2.3
Depression (Nagel 2018) 1.0 1.5 7.2 0.3 0.0 0.4 1.9 -0.1 0.5 -0.6 -2.7
Intelligence (Savage-Jansen 2018) 0.5 1.4 9.6 -0.3 0.0 -0.5 -0.7 -0.8 -0.2 3.1 0.3
Neuroticism (Nagel 2018) 0.8 1.8 8.0 -1.3 0.0 -1.8 0.0 -0.3 -2.8 0.8 -0.9
Schizophrenia (2018) 1.3 2.8 6.9 0.8 0.0 2.0 2.6 -1.8 1.8 0.8 -2.0
Schizophrenia vs Biploar Disorder 0.4 0.6 1.8 0.9 0.0 0.6 0.4 -0.1 0.4 1.1 1.4
Worry (Nagel 2018) 1.4 2.9 8.0 -2.1 0.0 -2.8 -0.3 1.2 -2.8 1.0 -0.3
Alzheimer’s Disease (in mother) 1.0 1.1 5.0 -1.1 0.0 -0.6 -1.0 -1.0 0.6 -2.2 -0.4
Alzheimer’s Disease (in father) 0.2 0.2 0.9 -0.5 0.0 -0.4 -0.2 0.1 -0.9 0.5 0.5
Alzheimer’s Disease (including proxy) 0.3 0.5 2.3 -0.8 0.0 -0.3 -0.5 -0.9 -0.1 -1.5 0.0
Crohns Disease (2017) 0.2 0.4 1.5 -0.5 0.0 -0.1 0.7 0.1 0.4 -0.8 -1.2
Irritable Bowel Disease (IBD) 0.1 0.3 1.1 -0.0 0.0 -0.1 0.7 0.2 0.4 -0.9 -1.0
Ulcerative Colitis (UC) 0.1 0.1 0.6 -0.3 0.0 -0.4 0.0 0.0 0.3 -0.8 -0.2
Major Depression (MDD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Reaction Time 0.9 1.7 6.3 -1.8 0.0 -1.8 -0.5 -0.4 -0.3 -2.5 0.4
Verbal and Numeric Reasoning (VNR) 0.6 1.5 8.4 -0.1 0.0 -0.8 -0.2 -0.4 -1.3 2.9 1.1
Breast Cancer 0.1 0.4 0.9 -0.2 0.0 0.1 -0.8 -0.7 0.8 0.4 1.0
Ovarian Cancer 0.2 0.2 1.0 0.2 0.0 -0.4 0.6 0.1 -1.0 0.1 -0.5
Prostate Cancer 0.3 0.5 1.1 -1.0 0.0 -0.9 0.6 -1.0 -0.2 -0.3 -0.7
Age at First Birth 1.4 2.0 6.8 -2.6 0.0 -1.1 -1.7 -1.2 1.3 0.2 -1.4
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.4 0.5 1.8 -0.8 0.0 -1.3 -0.6 1.0 -0.7 -0.1 0.0
Coronary Artery Disease (CAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 0.2 0.3 0.8 -0.9 0.0 -0.2 0.3 -0.6 0.1 -0.6 -0.9
Mean Putamen Volume 0.7 0.8 2.0 1.2 0.0 0.8 1.4 1.1 0.6 0.6 -0.1
Fasting Glucose 1.5 1.7 5.7 2.4 0.0 2.2 1.3 0.4 -0.1 1.1 0.8
HbA1C 0.4 0.5 1.0 1.0 0.0 -0.3 0.6 0.9 -1.0 -0.1 0.6
HDL Cholesterol 0.8 1.4 4.9 1.0 0.0 1.5 1.1 -1.1 2.2 0.7 -0.2
LDL Cholesterol 1.3 2.1 7.3 1.1 0.0 2.1 1.1 0.7 2.7 0.6 1.3
Lupus 0.1 0.2 0.5 0.1 0.0 0.5 -0.0 -0.0 0.7 0.5 -0.5
Neuroticism (2016) 1.1 1.6 9.7 -0.3 0.0 -0.5 1.0 -0.8 -3.1 1.1 -0.2
Primary Biliary Cirrhosis 0.7 1.0 4.9 -1.2 0.0 -0.8 0.9 2.2 0.4 -0.4 -0.1
Rheumatoid Arthritis 0.8 1.1 5.4 0.7 0.0 0.5 -0.8 -0.2 -1.1 -2.3 1.0
Schizophrenia (2014) 1.6 3.5 11.5 1.5 0.0 2.2 3.4 -0.9 2.4 0.5 -1.7
Triglycerides 0.5 0.9 3.1 -0.2 0.0 0.3 -1.1 -0.6 -0.1 -1.4 1.8
Type 2 Diabetes (T2D) (2012) 0.4 0.5 1.7 0.0 0.0 -0.3 -1.3 0.9 0.3 -0.2 1.1
Ulcerative Colitis 0.9 1.2 4.6 -1.1 0.0 -1.1 -0.9 1.3 0.5 -2.2 0.4
Blood Eosinophil Count 0.3 2.2 13.9 -1.3 0.0 -0.4 0.5 -0.9 0.1 -3.7 -0.6
Blood Platelet Count 1.1 12.7 27.1 3.4 0.0 5.1 3.3 -2.3 -4.4 -5.2 -1.4
Blood Red Count 3.4 33.1 130.0 3.7 0.0 2.7 11.4 1.5 3.7 -3.3 -9.3
Blood White Count 0.5 3.7 14.4 0.9 0.0 2.0 1.6 -2.3 1.6 -3.8 -0.1
Heel T-Score 0.3 2.8 17.4 -1.1 0.0 -0.9 0.1 -0.0 -0.0 4.2 -1.6
BMI 0.2 1.0 5.4 0.4 0.0 -0.4 -2.3 0.3 0.9 0.3 1.0
Height 0.1 1.9 8.1 1.0 0.0 1.4 1.1 -1.1 -2.8 -1.1 -0.2
Waist Hip Ratio (WHR) 0.0 0.1 0.8 0.1 0.0 0.5 0.9 -0.0 0.3 -0.0 -0.1
Systolic Blood Pressure 0.1 0.5 1.3 -0.4 0.0 0.6 -0.8 -0.6 1.0 1.1 0.2
Smoking Status 0.2 0.4 1.9 0.8 0.0 0.3 0.2 -0.3 -1.4 -0.7 -0.3
Allergy or Eczema 0.9 2.4 8.1 1.2 0.0 0.6 2.8 0.6 -0.1 -1.3 -2.7
Cardiovascular Disease 0.8 2.6 9.7 -1.6 0.0 -0.5 -3.1 -1.8 1.9 0.7 1.2
Hypothyroidism (self reported) 1.6 3.6 11.5 2.5 0.0 2.6 2.1 -0.4 3.4 0.5 0.1
Respiratory disease 0.3 0.7 2.1 1.0 0.0 0.9 0.7 -1.2 -0.2 -1.5 0.1
Type 2 Diabetes (T2D) (2018) 0.4 0.7 1.8 -0.2 0.0 -0.8 -1.0 -1.2 1.3 0.1 -0.8
Lung FEV1/FVC ratio 0.5 2.7 10.3 0.7 0.0 0.9 -1.1 -0.2 2.2 3.2 1.9
Lung FVC 0.3 1.4 4.9 -1.5 0.0 -0.9 -2.2 0.3 -0.2 1.5 0.8
Neuroticism 0.5 1.2 4.6 -0.6 0.0 -1.3 0.3 -0.5 -2.1 1.3 -1.0
Chronotype (morning person) 1.6 3.6 8.3 -1.5 0.0 -2.4 0.6 2.9 -2.9 -1.5 -1.2
Hair Pigment 0.0 0.8 2.4 1.0 0.0 -0.0 -0.4 1.5 -0.2 1.5 0.2
Tanning 0.1 0.8 1.9 1.1 0.0 1.4 -0.8 -0.4 0.4 1.2 0.9
Hand grip strength (left) 0.2 0.6 3.2 0.6 0.0 0.3 1.0 0.2 -0.2 0.6 -1.8
Number of treatments/medications taken 0.4 0.7 3.0 -0.6 0.0 0.2 -1.0 -1.1 0.3 -1.7 -0.2
Average weekly spirits intake 1.9 2.4 6.0 -1.4 0.0 -2.4 -1.9 2.0 -2.0 -0.4 -0.1
Sensitivity / hurt feelings 0.6 1.1 6.3 -0.2 0.0 -0.3 -0.2 0.6 -2.5 1.1 0.9
Frequency of depressed mood in last 2 weeks 1.8 2.6 6.6 1.1 0.0 1.5 2.6 0.4 1.9 1.2 -2.3
Hearing difficulty/problems: Yes 2.2 3.4 7.7 2.4 0.0 2.8 2.7 -1.4 1.3 1.7 -0.0
Relative age of first facial hair 0.3 0.6 1.4 -0.8 0.0 -0.4 -1.1 -0.7 -0.8 -0.7 -1.2
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 2.4 1.6 0.0 1.3 1.1 -1.3 0.3 -0.4 0.3
Ever used hormone-replacement therapy (HRT) 1.0 1.2 2.7 -1.4 0.0 -1.6 0.1 1.0 -1.4 -0.2 -1.4
Ever had hysterectomy (womb removed) 0.6 0.7 1.7 -0.5 0.0 -1.2 -0.1 1.2 -1.3 0.9 -0.4
Systolic blood pressure, automated reading 0.5 1.4 3.1 -1.2 0.0 -1.2 -1.8 -0.8 -0.7 1.7 1.0
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.1 -0.4 0.0 -0.2 -0.4 -1.1 1.0 0.3 0.0
Angina 1.2 1.6 8.8 -0.9 0.0 -0.2 -1.4 -3.0 0.1 -0.4 1.1
Medication for hormone replacement therapy 0.6 0.7 1.6 1.2 0.0 0.8 1.2 0.5 1.3 0.3 -0.0
Vitamin and mineral supplements 0.1 0.1 0.7 -0.3 0.0 -0.4 0.0 0.2 -0.1 0.8 -0.2
Supplements: Zinc 2.1 2.3 6.3 1.6 0.0 1.8 1.1 1.1 2.5 1.7 1.1
Medication: Co-codamol 0.8 0.9 3.6 1.9 0.0 1.1 -0.4 -0.0 0.3 -0.0 1.4
Medication: Metformin 1.3 1.9 6.8 -0.5 0.0 -0.6 -1.8 -1.9 2.6 -0.4 -0.6
Diabetes (father) 1.6 2.0 10.7 1.2 0.0 0.9 1.0 1.0 3.3 -0.3 -1.1
Diabetes (mother) 1.8 2.3 7.2 -0.8 0.0 -0.6 -1.5 2.3 0.8 1.3 2.7
Severe depression (siblings) 0.4 0.4 1.0 -0.8 0.0 -0.4 0.8 0.7 -1.0 -0.7 -0.0
Pack years adult smoking proportion 1.7 2.6 8.9 1.8 0.0 2.0 0.8 0.5 1.8 3.0 0.8
Impedance of leg (right) 0.1 0.6 2.2 0.0 0.0 0.9 1.5 -0.9 0.5 -0.3 -0.9
Leg fat-free mass (left) 0.0 0.2 0.8 0.6 0.0 0.5 -0.4 0.9 0.3 -0.3 0.0
Trunk fat percentage 0.2 0.8 2.8 0.6 0.0 0.2 -0.6 0.4 1.6 -1.7 0.1
Hand grip strength (right) 0.1 0.3 1.1 -0.0 0.0 -0.2 -0.3 0.1 -1.1 -0.4 -0.8
Townsend deprivation index at recruitment 1.5 2.1 5.4 1.1 0.0 1.5 1.2 2.2 1.1 -2.3 -0.4
Current tobacco smoking 0.2 0.3 1.4 0.4 0.0 0.3 0.1 -0.8 -0.6 -1.2 -0.1
Average weekly fortified wine intake 0.3 0.3 1.1 -0.6 0.0 -0.3 -0.6 0.0 -1.0 -0.5 -0.6
Maternal smoking around birth 1.3 1.9 5.9 1.4 0.0 2.1 2.4 -0.7 1.4 0.1 -0.9
Fed-up feelings 0.4 0.8 4.1 0.3 0.0 0.0 1.0 -0.8 -0.6 -0.3 -2.0
Frequency of unenthusiasm / disinterest in last 2 weeks 1.3 1.8 6.0 -0.1 0.0 0.0 1.3 1.3 0.3 -2.1 -2.4
Relative age voice broke 0.6 0.9 3.7 0.1 0.0 0.5 0.1 -0.6 1.9 0.6 -1.5
Taking other prescription medications 0.8 1.3 5.8 0.3 0.0 0.7 1.0 -0.3 1.5 -2.4 -0.4
Age when periods started (menarche) 0.5 1.1 5.6 1.1 0.0 1.0 2.4 -0.3 -0.5 -0.6 -0.4
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 3.3 0.8 0.0 0.2 1.2 0.1 -0.9 1.8 -0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 1.7 0.6 0.0 -0.2 0.7 1.2 -0.7 1.3 -1.0
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.1 0.7 0.0 0.5 -0.7 0.5 1.0 0.7 0.6
Qualifications: CSEs or equivalent 0.6 0.8 2.8 1.7 0.0 1.3 1.0 -0.3 1.0 -0.4 -0.2
Serious illness, injury or assault to yourself 0.3 0.3 2.0 -0.2 0.0 0.3 -0.5 -0.2 0.0 -1.4 0.1
High blood pressure 0.4 1.1 2.6 -0.5 0.0 0.4 -1.4 -1.3 1.6 1.3 0.5
Hayfever, allergic rhinitis or eczema 0.9 2.0 8.3 0.5 0.0 0.4 2.4 0.5 0.1 -1.1 -2.9
Multivitamins +/- minerals 0.3 0.3 0.9 0.7 0.0 0.6 -0.5 0.1 1.0 -0.5 0.6
Stomach or abdominal pain in last month 0.5 0.6 1.3 0.4 0.0 1.0 0.3 0.3 1.2 1.1 0.9
Supplements: Glucosamine 1.3 1.7 5.0 2.2 0.0 1.9 1.7 0.8 1.0 -0.2 -0.1
Diverticular disease/diverticulitis (self-reported) 1.2 1.4 8.4 0.1 0.0 -0.0 0.4 2.9 0.9 -0.8 1.2
Medication: Atenolol 0.5 0.7 1.9 -0.3 0.0 0.6 0.8 0.0 1.4 1.3 -0.8
Medication: Levothyroxine sodium 0.5 0.9 2.7 0.8 0.0 1.0 0.6 -1.6 0.5 -1.7 -0.1
Sitting height 0.1 0.7 2.8 0.8 0.0 1.6 0.2 -0.2 0.1 1.7 -0.1
Chronic bronchitis/emphysema (father) 0.9 1.0 4.0 -1.0 0.0 -1.0 -0.6 0.4 -2.0 -0.2 1.3
High blood pressure (mother) 1.2 1.7 6.2 -0.3 0.0 -0.7 0.2 1.3 -2.5 1.9 1.3
Body mass index (BMI) 0.2 0.9 4.0 -0.6 0.0 -1.0 -2.0 0.7 1.0 -0.6 0.6
Impedance of leg (left) 0.2 0.8 4.3 0.3 0.0 0.8 2.1 -0.5 0.5 -0.2 -0.7
Leg predicted mass (left) 0.0 0.2 0.9 0.6 0.0 0.6 -0.4 0.9 0.4 -0.2 0.0
Trunk fat mass 0.1 0.5 1.8 0.6 0.0 0.3 -0.6 0.6 1.3 -1.2 0.1
Waist circumference 0.1 0.5 2.0 0.1 0.0 -0.0 -1.4 0.4 0.8 -0.2 0.9
Number of incorrect matches in round 0.2 0.3 1.6 0.4 0.0 0.4 -0.3 -0.5 -0.5 0.1 1.3
Past tobacco smoking 0.2 0.4 1.7 -0.3 0.0 0.3 -0.4 -0.7 1.3 1.0 -0.2
Alcohol usually taken with meals 1.0 1.6 3.3 1.8 0.0 1.6 0.8 1.1 0.4 1.5 1.6
Nervous feelings 0.7 1.3 6.3 -0.8 0.0 -1.7 -0.5 -0.1 -2.5 0.1 0.0
Frequency of tenseness / restlessness in last 2 weeks 1.7 2.6 10.0 2.1 0.0 1.6 3.2 0.9 1.1 0.1 -1.4
Hearing difficulty/problems with background noise 1.1 1.8 8.4 0.4 0.0 0.9 1.6 -1.3 0.7 2.9 0.5
Hair/balding pattern: Pattern 2 0.6 0.8 1.6 -0.9 0.0 -0.6 1.2 1.1 -1.0 -0.2 -1.3
Had menopause 0.9 1.1 2.8 -0.9 0.0 -0.6 -1.4 -0.7 -0.6 -1.7 1.3
Had other major operations 0.6 0.7 2.2 1.0 0.0 0.6 1.0 -0.8 0.2 -1.5 -0.3
Forced vital capacity (FVC) 0.1 0.5 1.3 0.9 0.0 1.1 -0.1 0.2 -0.8 1.0 0.3
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.8 2.5 0.5 0.0 0.1 1.3 1.1 -0.1 1.6 -0.9
Ever unenthusiastic/disinterested for a whole week 2.5 3.1 10.3 1.1 0.0 2.1 3.2 -0.3 0.9 -0.6 -2.7
Qualifications: None of the above 1.8 4.0 23.2 -1.6 0.0 -1.9 -0.3 -0.0 -0.8 -4.8 -1.3
Financial difficulties in last 2 years 1.0 1.3 4.3 1.1 0.0 1.4 0.3 2.1 1.1 -0.0 1.3
Mouth/teeth dental problems 1.4 2.1 3.8 -1.8 0.0 -1.5 -1.6 -1.4 -0.4 1.6 -1.9
Heart attack 0.4 0.6 1.7 -1.1 0.0 0.1 -0.7 -1.0 1.3 -0.5 0.3
Allergy 0.5 1.1 4.1 0.1 0.0 0.2 -1.5 -0.6 0.4 2.0 1.3
Pain all over the body in last month 1.4 1.5 4.3 -0.9 0.0 -0.5 -0.6 -1.5 1.1 -2.1 -1.7
Diabetes (self-reported) 0.4 0.6 3.6 0.8 0.0 -0.1 -0.1 0.2 1.9 0.9 -0.3
Hayfever/allergic rhinitis (self-reported) 0.9 1.2 5.2 0.3 0.0 0.1 1.8 -0.8 -0.4 0.5 -2.3
Medication: Ramipril 0.2 0.3 0.8 -0.4 0.0 0.4 -0.6 -0.5 0.9 -0.4 -0.7
Medication: Simvastatin 0.1 0.2 0.9 0.3 0.0 -0.0 -0.2 0.1 0.8 -0.2 0.9
Fluid intelligence score 0.9 1.9 7.1 1.1 0.0 -0.2 -1.1 -0.1 -0.5 2.3 2.7
Illnesses of siblings 0.3 0.4 1.2 0.8 0.0 0.4 -1.1 0.2 -0.4 0.3 1.1
Neuroticism score 0.6 1.3 5.3 -0.9 0.0 -1.5 0.1 0.3 -2.3 1.1 -0.9
Weight 0.1 0.3 0.9 0.2 0.0 0.0 -0.9 0.9 0.6 -0.6 0.2
Impedance of arm (right) 0.1 0.6 2.8 0.7 0.0 0.8 0.9 -0.3 0.5 -1.7 -0.1
Arm fat percentage (right) 0.2 0.8 2.3 0.1 0.0 -0.5 -1.3 0.4 1.5 -1.2 0.2
Trunk fat-free mass 0.0 0.2 0.7 0.2 0.0 0.3 -0.1 0.9 -0.5 0.8 0.1
Hip circumference 0.2 0.7 3.5 0.1 0.0 -0.1 -1.9 0.0 1.0 0.1 0.9
Time employed in main current job 1.8 2.1 11.6 -1.2 0.0 -0.4 1.6 -0.4 -0.4 -0.8 -3.4
Alcohol intake versus 10 years previously 0.5 0.7 1.8 1.3 0.0 1.3 0.5 0.1 1.4 -0.2 -0.3
Father’s age at death 0.7 0.9 2.6 1.2 0.0 0.4 1.0 1.6 -0.9 1.1 0.0
Worrier / anxious feelings 1.2 2.2 7.2 -1.9 0.0 -2.1 -1.1 0.6 -2.7 0.4 -0.1
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.3 4.6 2.1 0.0 1.8 1.3 0.1 1.0 0.4 -0.4
Falls in the last year 0.3 0.4 1.3 0.7 0.0 0.5 -0.5 0.8 0.6 -0.1 1.1
Hair/balding pattern: Pattern 3 0.7 1.0 4.3 1.2 0.0 1.0 -0.1 -0.3 0.9 2.1 0.4
Number of live births 1.8 2.5 6.9 -1.7 0.0 -2.6 -0.0 1.9 -2.6 -0.6 0.1
Forced expiratory volume in 1-second (FEV1) 0.3 0.9 3.9 1.1 0.0 1.2 -0.3 0.3 0.0 2.0 0.8
Pulse rate 0.3 0.5 2.1 1.5 0.0 0.5 -0.3 -0.1 1.0 -0.7 0.4
Happiness 0.7 0.9 2.5 0.7 0.0 0.5 1.6 0.8 0.4 -0.9 -1.6
Noisy workplace 0.2 0.2 0.9 0.9 0.0 0.6 0.4 -0.1 0.0 -0.6 -0.1
Qualifications: A levels/AS levels or equivalent 0.5 1.2 8.9 -0.6 0.0 0.2 -0.3 -0.3 -0.1 3.0 0.0
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.5 -0.7 0.0 -0.7 0.5 0.7 0.3 -0.3 0.0
Mouth/teeth dental problems: Dentures 0.7 1.1 2.3 1.5 0.0 1.3 0.5 0.9 1.5 -1.0 1.0
Asthma 0.4 0.7 3.3 -0.5 0.0 -0.2 0.3 -1.4 0.1 -1.8 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 2.5 0.5 0.0 0.8 -1.6 -1.0 0.8 0.1 0.7
Medication: Cholesterol lowering 0.3 0.4 1.3 -0.3 0.0 0.0 -1.0 0.6 1.1 -0.3 0.7
Depression (self-reported) 1.6 1.9 6.1 -0.6 0.0 -0.7 1.3 2.0 -1.5 -2.5 -0.7
Medication: Lansoprazole 0.5 0.5 2.0 0.8 0.0 1.4 0.1 -0.8 0.5 -0.7 0.5
Prospective memory result 0.3 0.3 1.3 -0.5 0.0 -0.5 -0.0 -0.3 -1.2 -0.7 -0.3
Lung cancer (father) 0.3 0.3 1.3 -0.7 0.0 -0.1 -0.2 1.1 -0.4 0.7 0.1
Illnesses of mother 1.5 1.8 4.6 1.3 0.0 0.9 0.3 -2.1 1.0 -1.7 -1.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.2 3.7 1.1 0.0 1.2 -0.4 0.1 0.7 1.9 1.4
Pulse wave Arterial Stiffness index 0.5 0.6 2.5 -0.6 0.0 -0.3 -1.1 -0.6 1.6 -0.3 0.0
Impedance of arm (left) 0.3 1.3 2.6 1.4 0.0 1.6 1.5 -0.6 1.1 -1.3 -0.3
Arm fat mass (right) 0.2 0.6 2.0 -0.2 0.0 -0.4 -1.3 0.4 1.4 -1.0 0.1
Trunk predicted mass 0.0 0.2 0.8 0.2 0.0 0.3 -0.1 0.9 -0.5 0.8 0.2
Standing height 0.1 1.5 4.6 1.5 0.0 2.1 2.0 0.3 -0.4 -0.2 -0.6
Length of working week for main job 1.5 1.7 9.2 1.1 0.0 1.4 0.1 0.3 3.0 0.7 0.7
Exposure to tobacco smoke at home 0.7 0.8 4.8 0.8 0.0 -0.3 0.1 2.2 -0.4 -0.1 1.0
Breastfed as a baby 0.5 0.6 2.9 0.3 0.0 0.1 -1.0 0.5 0.6 0.5 1.7
Tense / ‘highly strung’ 0.2 0.3 1.2 0.4 0.0 -0.4 0.6 0.3 -0.3 1.1 -0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 2.6 0.5 0.0 0.1 1.4 1.6 -0.7 1.1 0.0
Hair/balding pattern: Pattern 4 1.0 2.3 5.9 2.0 0.0 2.4 0.8 -2.1 1.8 -0.0 0.2
Birth weight of first child 0.8 1.4 5.8 1.6 0.0 0.3 1.0 -0.1 -2.4 1.4 -0.6
Peak expiratory flow (PEF) 0.5 1.1 6.3 0.4 0.0 1.1 -0.1 0.7 0.1 2.5 0.9
Pulse wave reflection index 0.1 0.1 0.4 -0.6 0.0 -0.5 -0.4 -0.0 0.1 0.0 -0.3
Ever highly irritable/argumentative for 2 days 3.4 4.1 15.1 3.0 0.0 3.9 1.9 -1.1 1.7 -0.6 -0.5
Loud music exposure frequency 0.9 1.0 2.5 1.2 0.0 1.6 -0.6 -0.9 0.3 -1.5 0.6
Qualifications: O levels/GCSEs or equivalent 0.6 1.0 7.2 0.4 0.0 0.8 -0.1 0.1 0.0 2.7 0.4
Mouth/teeth dental problems: Bleeding gums 1.0 1.3 2.6 1.6 0.0 1.6 1.3 -0.3 0.1 -0.8 1.6
Blood clot in the leg (DVT) 1.0 1.3 3.0 1.7 0.0 1.6 0.3 -0.2 1.7 -1.0 1.0
Medication: Paracetamol 0.8 1.3 2.9 -1.5 0.0 -1.6 -1.7 0.6 -0.9 -1.4 -0.3
Headache pain in last month 0.4 0.7 1.5 1.1 0.0 1.0 0.1 -0.9 0.4 1.2 0.7
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.9 -0.2 0.0 -0.4 0.5 -0.7 -1.4 -0.7 -0.8
Glaucoma (self-reported) 0.6 0.7 3.0 0.1 0.0 -0.2 -0.8 0.0 0.6 -1.3 1.7
Gout (self-reported) 0.5 0.7 2.1 0.8 0.0 1.1 0.5 -1.1 1.5 0.2 0.1
Hypothyroidism/myxoedema (self-reported) 1.0 1.9 5.3 1.6 0.0 1.8 1.5 -0.9 2.3 -0.8 -0.5
Medication: Amlodipine 0.8 1.2 5.7 -0.2 0.0 0.1 -0.8 -2.4 1.6 0.7 0.1
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.5 -0.6 0.0 0.1 0.3 -1.2 1.2 -0.4 0.1
Birth weight 1.8 4.0 12.6 1.9 0.0 -0.5 0.1 3.6 -3.1 2.0 1.3
Chronic bronchitis/emphysema (mother) 0.4 0.5 1.5 0.0 0.0 0.4 1.1 -0.7 0.2 1.2 -0.7
High blood pressure (siblings) 0.3 0.4 1.1 -1.0 0.0 -0.3 0.2 -0.6 0.3 1.0 0.3
Forced vital capacity (FVC), Best measure 0.2 0.6 1.5 1.2 0.0 1.2 0.3 -0.1 -0.0 1.0 0.7
Body fat percentage 0.2 0.7 2.8 0.3 0.0 -0.1 -0.9 0.5 1.7 -1.3 0.2
Leg fat percentage (right) 0.1 0.4 1.5 -0.2 0.0 -0.5 -1.2 0.5 1.2 -0.1 0.4
Arm fat-free mass (right) 0.0 0.2 0.6 0.4 0.0 0.7 0.0 0.7 0.5 0.4 -0.2
Exposure to tobacco smoke outside home 0.4 0.6 1.3 1.1 0.0 0.8 1.1 0.7 0.7 0.4 -0.7
Comparative body size at age 10 0.4 1.2 3.7 0.5 0.0 -1.4 -0.8 1.3 -1.9 1.1 -0.2
Number of full brothers 0.3 0.4 1.3 -1.2 0.0 -0.4 0.6 0.5 0.1 0.9 -0.1
Worry too long after embarrassment 0.6 1.0 3.9 -2.0 0.0 -1.1 -1.4 -0.8 -0.6 0.0 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.2 1.5 4.8 1.1 0.0 1.7 2.2 0.4 1.1 1.4 -0.3
Wheeze or whistling in the chest in last year 0.5 0.9 2.8 -1.7 0.0 -1.0 0.2 0.6 -0.3 -1.4 -0.8
Number of children fathered 1.0 1.1 3.6 0.2 0.0 -0.8 0.2 1.9 -1.0 1.9 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.5 1.3 -0.6 0.0 -1.1 -0.8 0.7 0.4 -0.4 1.1
Age at first live birth 0.3 0.5 1.9 -0.9 0.0 0.1 -0.2 -0.2 0.9 1.4 -0.4
Pulse wave peak to peak time 0.5 0.6 2.5 0.6 0.0 0.4 1.1 0.7 -1.6 0.3 0.1
Health satisfaction 1.0 1.3 2.9 1.1 0.0 1.1 1.7 -0.9 1.0 -1.5 -1.0
Shortness of breath walking on level ground 0.8 0.9 2.4 1.5 0.0 1.2 0.3 -1.6 -1.1 0.4 0.1
Qualifications: College or University degree 0.6 1.8 9.3 1.2 0.0 1.6 0.0 0.1 0.8 3.0 0.9
Eye problems/disorders: None of the above 0.2 0.3 1.5 -0.5 0.0 0.3 -0.3 0.3 0.1 1.2 -0.3
Mouth/teeth dental problems: Loose teeth 0.3 0.3 1.7 -0.6 0.0 -0.4 0.3 0.4 -1.3 -0.2 -0.1
Emphysema/chronic bronchitis 0.5 0.6 1.1 1.0 0.0 1.1 0.4 -0.6 -1.0 -0.8 0.8
Medication for pain relief, constipation, heartburn 0.7 1.2 3.6 1.3 0.0 1.0 1.7 -0.1 0.1 1.9 0.6
Neck or shoulder pain in last month 1.1 1.6 3.1 1.6 0.0 1.0 1.7 1.8 -0.8 -0.4 1.5
Medication: Blood pressure 0.3 0.5 1.8 -0.3 0.0 0.8 -0.6 0.3 1.3 0.9 -0.3
Angina (self-reported) 1.1 1.4 7.7 -0.8 0.0 0.1 -1.3 -2.8 0.2 -0.1 1.2
Migraine (self-reported) 0.6 0.8 1.7 -0.9 0.0 -0.7 -1.0 1.1 -0.5 -1.3 0.8
Medication: Ibuprofen 0.2 0.2 0.9 -0.2 0.0 -0.1 -0.9 -0.5 0.4 -0.4 0.0
Medication: Allopurinol 0.5 0.6 2.2 0.8 0.0 0.9 -0.1 0.2 1.5 0.7 0.8
Medication: Omeprazole 0.8 0.9 2.4 -0.8 0.0 -0.4 0.6 1.3 0.8 -1.2 -1.6
Medication: Seretide 50 evohaler 0.2 0.2 0.6 -0.8 0.0 -0.4 -0.5 -0.5 0.0 -0.3 -0.2
Mean time to correctly identify matches 0.6 1.1 3.0 -1.7 0.0 -1.7 -0.1 -0.2 -0.3 -1.7 -0.2
Heart disease (mother) 0.7 0.9 3.5 -0.5 0.0 -0.4 -0.1 0.6 -0.7 1.6 1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.2 0.4 0.2 0.0 0.6 0.4 0.4 0.6 0.3 0.5
Whole body fat mass 0.1 0.4 1.8 0.3 0.0 0.1 -0.8 0.6 1.3 -0.7 0.2
Leg fat mass (right) 0.1 0.4 1.4 0.0 0.0 -0.3 -1.2 0.7 0.9 -0.1 0.5
Arm predicted mass (right) 0.0 0.2 0.5 0.5 0.0 0.7 0.5 0.5 0.6 0.6 -0.4
Pulse rate, automated reading 0.3 0.8 2.4 1.5 0.0 0.6 -0.6 0.2 1.3 -1.3 0.5
Alcohol intake frequency. 0.4 1.0 4.3 -1.0 0.0 -0.4 1.2 0.2 -1.0 -2.1 -0.8
Comparative height size at age 10 0.3 1.7 6.1 -0.7 0.0 -1.0 -0.0 1.0 -2.2 -2.5 -0.2
Number of full sisters 0.6 0.7 2.5 -0.7 0.0 -0.9 1.6 0.8 0.4 -0.2 -0.9
Suffer from ‘nerves’ 0.6 1.0 2.3 -1.2 0.0 -1.5 0.1 0.1 -1.5 0.9 -1.0
Overall health rating 0.7 1.4 4.1 1.0 0.0 1.1 0.0 -2.0 1.5 -1.6 0.3
Chest pain or discomfort 0.2 0.3 1.1 0.1 0.0 0.4 0.8 -0.4 1.1 0.1 0.1
Had major operations 2.0 2.3 6.2 2.2 0.0 1.7 1.1 1.4 0.9 2.5 0.9
Age at last live birth 0.3 0.4 1.1 -1.1 0.0 -0.2 -0.8 -0.7 -0.1 0.7 0.6
Family relationship satisfaction 1.4 1.7 4.7 0.8 0.0 1.5 0.9 -1.5 2.2 1.2 -1.3
Leg pain on walking 1.7 2.1 6.0 1.4 0.0 1.4 2.5 1.4 2.2 -0.1 -0.2
Qualifications: NVQ or HND or HNC or equivalent 0.7 0.8 2.6 1.1 0.0 0.9 0.6 0.9 0.1 1.6 0.9
Commuting to job workplace: Car/motor vehicle 0.5 0.6 2.4 -0.3 0.0 -0.4 -1.1 0.4 -0.0 0.9 1.6
Illness, injury, bereavement, stress in last 2 years 0.3 0.3 1.3 0.4 0.0 -0.4 0.3 -1.1 -0.6 0.8 -0.2
Medication: Aspirin 0.2 0.3 1.1 -0.0 0.0 0.5 -0.1 -1.0 0.7 0.4 -0.6
Supplements: Vitamin C 1.2 1.4 6.2 0.6 0.0 1.3 1.6 0.0 2.5 0.0 -0.6
Knee pain experienced in last month 0.7 1.1 3.7 0.5 0.0 -0.1 -0.4 1.8 -0.6 -1.0 1.9
Hypertension (Self-reported) 0.5 1.5 4.2 -1.1 0.0 -0.1 -2.0 -1.5 1.4 1.3 0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 1.7 -0.7 0.0 -0.5 -1.0 0.9 -0.8 -1.3 -0.3
Illnesses of father: Heart disease 0.5 0.7 2.3 -0.8 0.0 -0.1 -1.5 -1.4 0.5 -0.4 -0.4
Illnesses of siblings: Diabetes 1.2 1.4 5.0 1.1 0.0 0.7 2.2 0.1 0.9 -0.9 -1.8
Smoking status: Previous 0.4 0.6 2.0 0.8 0.0 0.3 1.1 1.4 -0.8 -0.1 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.2 0.9 -0.1 0.0 0.7 0.3 -0.0 -0.9 0.1 -0.5
Whole body fat-free mass 0.0 0.2 0.7 0.4 0.0 0.5 -0.3 0.8 0.0 0.3 0.1
Leg fat-free mass (right) 0.1 0.3 1.3 0.9 0.0 0.6 0.0 1.1 0.3 -0.2 0.1
Arm fat percentage (left) 0.2 0.8 3.0 0.2 0.0 -0.3 -1.2 0.2 1.7 -1.2 0.1
Average weekly red wine intake 0.9 1.3 5.9 -0.3 0.0 -1.4 -0.4 0.9 -1.1 2.4 0.1
Handedness (chirality/laterality): Left-handed 0.3 0.3 1.2 0.1 0.0 0.5 -0.4 0.7 -0.2 1.1 0.8
Mood swings 0.4 0.8 4.2 -0.5 0.0 -1.0 0.1 -0.7 -0.2 -0.3 -2.0
Loneliness, isolation 1.2 1.6 7.1 -0.4 0.0 -0.3 1.7 -1.2 -0.8 0.7 -2.7
Long-standing illness, disability or infirmity 0.9 1.4 3.7 0.9 0.0 1.2 1.7 0.1 1.5 -1.9 0.2
Ever had bowel cancer screening 0.3 0.3 0.8 -0.5 0.0 -0.5 -0.9 0.2 0.0 -0.6 -0.9
Diabetes diagnosed by doctor 0.4 0.6 3.4 0.7 0.0 -0.1 -0.1 -0.3 1.8 -0.1 -0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.5 0.2 0.0 0.3 0.1 -0.7 0.5 -0.1 -0.2
Friendships satisfaction 0.3 0.4 1.0 -0.6 0.0 0.1 0.5 -1.0 0.6 1.0 -0.5
Qualifications: nursing, teaching 0.8 1.2 6.7 -1.2 0.0 -0.5 -1.2 -0.1 0.4 2.6 -0.0
Commuting to job workplace: Walk 0.5 0.6 1.4 0.9 0.0 0.8 1.2 0.5 -0.4 -0.0 -1.1
Eye problems/disorders: Cataract 0.2 0.2 0.7 0.6 0.0 -0.0 -0.3 0.3 -0.5 -0.3 0.8
Mouth/teeth dental problems: Mouth ulcers 0.6 1.0 2.1 1.0 0.0 1.2 1.2 1.3 0.1 -0.4 1.4
Medication for cholesterol 0.4 0.6 2.0 -0.2 0.0 -0.3 1.3 1.4 -0.9 0.0 -0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.0 1.2 4.0 -1.3 0.0 -2.0 -0.5 -0.0 -1.8 0.3 -0.7
Back pain experienced in last month 1.0 1.5 4.2 1.9 0.0 1.4 -0.1 1.2 0.5 0.7 2.0
Mineral and other dietary supplements 0.6 0.7 3.2 0.5 0.0 0.8 0.3 -0.9 0.9 1.8 0.2
Breast cancer (self-reported) 0.7 0.9 3.9 -0.1 0.0 -0.0 -2.0 -1.3 -0.8 0.5 0.6
Asthma (self-reported) 0.3 0.5 2.5 -0.0 0.0 0.2 0.6 -1.0 0.3 -1.6 0.3
Osteoporosis (self-reported) 1.5 1.8 4.5 -1.3 0.0 -1.4 -1.3 -0.9 -1.9 -2.1 -0.0
Osteoarthritis (self-reported) 1.2 1.5 10.8 0.5 0.0 0.4 0.1 0.4 0.9 -3.3 -0.1
Medication: Aspirin 0.4 0.5 2.1 -0.1 0.0 0.2 -0.2 -1.4 0.8 0.8 -0.7
Medication: Gliclazide 0.5 0.6 1.4 -0.6 0.0 -0.6 0.6 -1.2 0.7 -0.7 -1.1
Illnesses of father: None of the above (group 1) 0.1 0.2 0.4 -0.0 0.0 -0.2 0.5 -0.5 -0.3 -0.4 -0.7
Smoking status: Current 0.3 0.4 1.5 0.0 0.0 -0.2 -0.3 -0.7 -1.1 -1.2 -0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.6 10.4 -1.2 0.0 -1.6 -3.2 -0.6 0.2 1.8 1.7
Whole body water mass 0.0 0.2 0.6 0.5 0.0 0.6 -0.2 0.8 0.2 0.5 -0.0
Leg predicted mass (right) 0.1 0.4 1.5 1.0 0.0 0.8 0.1 1.2 0.4 -0.1 0.1
Arm fat mass (left) 0.1 0.6 1.7 0.0 0.0 -0.3 -1.2 0.3 1.3 -1.2 -0.1
Number of self-reported non-cancer illnesses 1.0 1.7 4.0 1.9 0.0 2.0 0.8 -0.6 2.0 -0.8 0.9
Average weekly champagne plus white wine intake 0.7 1.0 4.1 0.7 0.0 0.7 1.5 0.3 0.7 2.0 0.4
Miserableness 1.0 1.7 7.6 1.1 0.0 0.7 2.8 -0.0 0.5 -0.0 -2.1
Guilty feelings 0.3 0.5 1.3 -1.1 0.0 -0.7 -1.1 0.2 -0.2 0.4 0.9
Wears glasses or contact lenses 0.5 0.6 1.4 -0.8 0.0 -0.1 -1.1 -0.8 -1.2 0.8 0.4
Ever taken oral contraceptive pill 0.3 0.3 1.3 0.4 0.0 0.6 0.8 -0.2 0.1 1.2 0.1
Hearing aid user 0.4 0.5 2.0 0.1 0.0 0.3 1.0 1.4 0.1 -0.1 -1.0
Mother’s age at death 2.9 3.6 10.6 -2.7 0.0 -2.9 -1.4 0.0 -3.3 -0.3 -0.9
Financial situation satisfaction 0.6 0.7 2.1 1.3 0.0 1.2 1.4 0.6 -0.4 -0.5 -0.3
Tinnitus: Yes, now most or all of the time 0.8 0.9 2.1 0.6 0.0 1.4 1.3 -0.8 1.0 0.8 0.8
Commuting to job workplace: Public transport 0.2 0.3 1.5 -0.1 0.0 0.5 0.2 -0.5 -0.2 -1.2 0.1
Eye problems/disorders: Glaucoma 1.0 1.2 3.9 -1.3 0.0 -2.0 -0.4 0.3 -0.6 -1.8 0.1
Medication: Blood pressure 1.0 1.8 6.2 -1.7 0.0 -1.0 -2.5 -2.0 0.1 0.5 0.2
Pain type(s) experienced in last month: Hip pain 1.2 1.5 3.4 1.6 0.0 1.0 1.8 1.0 0.6 0.5 -1.8
Supplements: Fish oil (including cod liver oil) 0.7 0.9 2.3 -0.7 0.0 -1.1 0.4 1.2 -0.4 -1.5 -1.3
High cholesterol (Self-reported) 0.3 0.5 1.9 0.5 0.0 0.2 -0.5 0.5 1.4 -0.3 1.0
Medication: Bendroflumethiazide 1.5 2.2 6.8 -1.4 0.0 -0.9 -2.1 -2.6 -1.7 -0.0 -0.7
Medication: Paracetamol 1.0 1.5 3.1 -1.6 0.0 -1.5 -1.7 0.6 -1.0 -1.8 -0.1
Medication: Lisinopril 0.5 0.6 3.5 0.5 0.0 0.6 -0.1 -0.2 1.9 0.8 0.4
Medication: Atorvastatin 0.4 0.5 1.8 -0.1 0.0 0.1 -0.7 0.7 1.1 1.3 0.4
Illnesses of father: High blood pressure 0.6 0.7 1.9 0.6 0.0 0.3 1.4 1.4 -0.2 0.6 -1.0
Alcohol drinker status: Never 0.7 0.8 2.4 0.5 0.0 1.1 0.4 -1.4 1.6 -0.1 -0.5
Ever smoked 0.3 0.6 2.1 0.5 0.0 -0.4 0.1 0.4 -1.5 -1.3 0.7
Basal metabolic rate 0.0 0.2 0.9 0.4 0.0 0.3 -0.4 0.9 0.1 0.1 0.0
Leg fat percentage (left) 0.1 0.4 1.6 -0.2 0.0 -0.7 -0.8 0.7 1.3 -0.1 0.4
Arm fat-free mass (left) 0.0 0.1 0.2 0.1 0.0 0.1 -0.2 0.5 -0.0 0.0 -0.4
Number of operations (self-reported) 0.6 0.9 2.7 1.6 0.0 0.8 1.4 0.6 -0.7 -0.8 0.3
Average weekly beer plus cider intake 0.3 0.4 2.0 0.4 0.0 0.3 0.3 -1.4 -0.4 -0.8 0.3
Irritability 0.7 1.1 3.5 0.7 0.0 0.0 0.8 -1.0 -1.9 1.3 -1.2
Risk taking 3.4 5.0 13.2 2.3 0.0 2.1 2.5 3.6 2.2 2.2 1.3
Ever had prostate specific antigen (PSA) test 2.0 2.3 15.2 0.5 0.0 -1.1 0.2 3.9 -0.6 1.3 -0.0
Fractured/broken bones in last 5 years 1.1 1.5 4.3 2.0 0.0 2.1 1.7 0.2 0.2 -0.6 -0.2
Age started oral contraceptive pill 0.5 0.6 2.6 0.6 0.0 0.3 -0.3 -0.6 0.3 1.0 1.6
Diastolic blood pressure, automated reading 0.3 0.8 2.6 -0.8 0.0 -1.3 -1.6 -0.6 -0.6 0.5 0.8
Ever depressed for a whole week 0.4 0.4 2.5 0.4 0.0 0.4 0.6 -0.3 -0.5 0.1 -1.6
Unable to work because of sickness or disability 1.5 1.9 6.5 2.2 0.0 2.6 0.2 0.1 1.9 -0.3 0.4
Commuting to job workplace: Cycle 1.1 1.3 4.8 0.6 0.0 0.4 1.0 0.1 1.9 2.2 -0.8
Myopia 1.1 1.6 3.8 -0.1 0.0 0.6 -1.5 -1.4 1.4 -1.7 1.9
Vascular/heart problems diagnosed by doctor 0.5 1.3 3.4 1.1 0.0 0.2 1.8 1.2 -1.5 -1.0 -1.1
Cholesterol lowering medication 0.2 0.3 1.7 0.2 0.0 0.2 0.1 -0.2 1.3 -0.3 0.4
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 1.2 -0.9 0.0 -0.5 -0.4 0.9 -0.1 -1.1 -1.1
Pain experienced in last month 0.9 1.5 5.1 -2.2 0.0 -2.0 -1.1 -0.2 -1.1 -0.4 -0.6
Supplements: Calcium 0.3 0.3 1.1 1.1 0.0 0.9 0.6 -0.0 0.1 0.6 -0.2
Basal cell carcinoma (self-reported) 0.3 0.3 1.6 0.3 0.0 0.7 -0.1 0.3 0.4 0.3 1.2
Heart attack/myocardial infarction (self-reported) 0.5 0.7 3.1 -1.0 0.0 0.2 -0.5 -1.0 1.8 -0.3 0.2
Deep venous thrombosis (DVT) (self-reported) 0.9 1.1 3.1 1.8 0.0 1.4 0.2 -0.1 1.4 -0.9 1.0
Heart disease (siblings) 0.2 0.3 0.8 -0.5 0.0 -0.9 0.4 0.2 0.0 0.7 -0.4
Alcohol drinker status: Previous 1.2 1.4 4.1 -1.3 0.0 -1.7 0.0 1.5 -2.0 -0.0 -0.1
Pack years of smoking 1.4 2.1 7.5 1.5 0.0 1.7 0.4 0.5 1.6 2.7 1.1
Impedance of whole body 0.3 1.3 3.6 0.7 0.0 1.3 1.9 -0.7 0.8 -1.7 -0.8
Leg fat mass (left) 0.1 0.4 1.0 0.1 0.0 -0.3 -1.0 0.7 0.9 -0.1 0.5
Arm predicted mass (left) 0.0 0.1 0.7 0.1 0.0 0.1 -0.1 0.8 -0.0 0.4 -0.3