TWAS hub - MARVELD2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0260	0.0171	0.00053	0.017	0.015	0.014	NA	0.015	0.00019	0.00039	5.6e-04	NA	0.00034
2	TCGA	Head and Neck Squamous Cell Carcinoma	0.0221	0.0160	0.00380	0.023	0.022	0.006	NA	0.019	0.00100	0.00160	6.3e-02	NA	0.00300
3	TCGA	Thyroid Carcinoma	0.0700	0.0540	0.00014	0.036	0.032	0.049	NA	0.026	0.00019	0.00038	1.4e-05	NA	0.00140

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Lung cancer (father)	4.1	4.8	6.7	-1.8	-2.6	-2.0
Blood White Count	3.5	26.1	47.7	0.0	-6.9	-5.5
Chest pain or discomfort	3.2	4.6	5.2	1.9	2.2	2.3
Bilateral oophorectomy (both ovaries removed)	2.8	3.3	4.6	2.1	1.5	1.7
Hypothyroidism/myxoedema (self-reported)	2.7	5.3	6.8	1.6	2.6	2.5
Angina (self-reported)	2.7	3.6	4.8	1.2	2.1	2.2
HbA1C	2.5	2.8	7.1	-0.2	1.1	2.7
Chronotype (morning person)	2.5	5.7	6.2	2.3	2.5	2.4
Angina	2.4	3.1	4.1	1.2	1.9	2.0
Medication: Co-codamol	2.3	2.7	4.1	0.5	2.0	2.0
Medication: Ventolin 100micrograms inhaler	2.3	2.9	4.0	-1.2	-1.8	-2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.8	4.9	1.1	1.5	2.2
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.5	6.0	-2.5	-0.8	-1.0
Unable to work because of sickness or disability	2.1	2.7	3.5	1.1	1.8	1.9
Ovarian Cancer	2.0	2.7	4.2	-0.9	-2.0	-1.7
Depression (self-reported)	2.0	2.4	4.3	0.4	1.6	2.1
Prospective memory result	2.0	2.5	3.2	-1.8	-1.4	-1.5
Worry too long after embarrassment	2.0	3.3	5.3	-0.9	2.0	2.3
Hearing difficulty/problems: Yes	1.9	2.9	4.5	-1.1	-2.1	-1.7
Triglycerides	1.8	2.9	3.3	1.5	1.8	1.8
Hypothyroidism (self reported)	1.8	4.0	5.2	1.4	2.3	2.3
Other serious medical condition/disability diagnosed by doctor	1.8	2.4	4.1	2.0	1.6	0.6
Eye problems/disorders: Glaucoma	1.8	2.1	3.6	0.6	-1.9	-1.6
Breast Cancer	1.7	4.1	8.3	-2.9	-1.4	-1.4
Medication: Allopurinol	1.7	2.3	2.6	-1.3	-1.6	-1.6
Smoking status: Current	1.7	2.7	4.7	-0.0	-1.8	-2.2
Blood clot in the leg (DVT)	1.6	2.1	4.3	-0.2	-1.4	-2.1
Irritability	1.6	2.7	4.7	0.9	2.2	1.6
Deep venous thrombosis (DVT) (self-reported)	1.6	2.0	4.2	-0.5	-1.3	-2.0
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.4	3.8	1.3	1.9	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	2.6	1.3	1.6	1.6
Vascular/heart problems diagnosed by doctor	1.5	4.0	8.4	-1.5	-1.1	-2.9
Stomach or abdominal pain in last month	1.4	1.8	3.5	-0.1	1.3	1.9
Suffer from ‘nerves’	1.4	2.2	4.1	-0.7	2.0	1.4
Supplements: Vitamin C	1.4	1.6	2.4	-0.3	1.6	1.5
Medication: Simvastatin	1.3	1.9	2.3	1.5	1.3	1.3
Pulse wave Arterial Stiffness index	1.3	1.5	2.5	0.4	1.4	1.6
Tense / ‘highly strung’	1.3	2.2	3.7	1.0	1.4	1.9
Wheeze or whistling in the chest in last year	1.3	2.4	3.6	-1.3	-1.4	-1.9
Current tobacco smoking	1.2	2.0	3.8	0.3	-1.5	-1.9
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	1.8	0.8	1.2	1.4
Number of live births	1.2	1.7	3.7	-0.1	-1.1	-1.9
Medication: Lansoprazole	1.2	1.4	2.8	0.3	1.1	1.7
Loud music exposure frequency	1.2	1.3	1.7	-1.0	-1.3	-1.1
Medication for cholesterol, blood pressure or diabetes	1.2	1.9	3.2	-1.3	-0.9	-1.8
Gout (self-reported)	1.2	1.6	2.8	0.2	-1.4	-1.7
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.5	-1.0	0.8	1.6
Ever had hysterectomy (womb removed)	1.1	1.2	3.3	1.8	0.5	-0.2
Diabetes (father)	1.1	1.3	2.0	-0.6	1.4	1.3
High blood pressure	1.1	3.1	6.1	1.5	1.0	2.5
Supplements: Glucosamine	1.1	1.5	2.7	1.3	1.6	0.2
High blood pressure (mother)	1.1	1.6	1.9	-1.2	-1.4	-1.2
Pulse wave peak to peak time	1.1	1.3	2.1	-0.5	-1.3	-1.4
Family relationship satisfaction	1.1	1.4	2.6	-0.2	1.2	1.6
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	2.7	-1.0	1.6	1.3
Medication for cholesterol	1.1	1.7	3.2	-1.2	-0.7	-1.8
Financial situation satisfaction	1.1	1.4	3.3	1.8	0.9	-0.2
High cholesterol (Self-reported)	1.1	1.9	2.5	0.9	1.5	1.6
Fractured/broken bones in last 5 years	1.1	1.4	2.1	-0.6	-1.3	-1.5
Ever used hormone-replacement therapy (HRT)	1.0	1.2	2.0	0.8	1.0	1.4
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	4.3	2.1	1.1	1.2
Nervous feelings	1.0	1.8	3.1	-0.8	1.3	1.8
Heart attack	1.0	1.2	1.9	-1.1	0.8	1.4
Allergy	1.0	2.3	2.6	1.4	1.6	1.5
Breastfed as a baby	1.0	1.2	2.7	-1.6	-0.9	-0.4
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.1	-0.7	1.1	1.5
Number of full sisters	1.0	1.3	2.1	0.5	-1.2	-1.4
Neuroticism (Nagel 2018)	0.9	2.1	4.6	0.5	2.1	1.2
Neuroticism (2016)	0.9	1.3	3.1	0.2	0.9	1.8
Neuroticism	0.9	2.2	3.5	-0.4	1.9	1.7
Sensitivity / hurt feelings	0.9	1.5	2.7	-0.3	1.6	1.3
Number of incorrect matches in round	0.9	1.5	2.2	-1.3	-1.5	-0.7
Hearing difficulty/problems with background noise	0.9	1.5	1.8	-1.0	-1.3	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	2.5	1.6	1.3	1.4
Mouth/teeth dental problems	0.9	1.4	3.1	0.4	-1.8	-1.1
Neuroticism score	0.9	1.8	3.1	-0.5	1.8	1.5
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	1.8	-1.3	-0.7	-1.0
Medication: Cholesterol lowering	0.9	1.5	2.0	1.4	0.6	1.4
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	3.1	-1.8	-0.8	-0.9
Number of full brothers	0.9	1.1	1.7	-0.3	-1.3	-1.2
Had major operations	0.9	1.0	2.1	1.4	0.7	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	1.8	-0.3	-1.3	-1.1
Wears glasses or contact lenses	0.9	1.0	2.0	1.4	0.7	-0.8
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.9	-1.7	-0.3	-0.8
Bipolar Disorder (2018)	0.8	1.2	2.1	1.4	0.4	-1.2
Schizophrenia vs Biploar Disorder	0.8	1.1	2.1	-1.4	-1.1	-0.4
Type 2 Diabetes (T2D) (2012)	0.8	1.0	2.1	0.0	0.9	1.4
Cardiovascular Disease	0.8	2.5	5.3	1.0	1.1	2.3
Relative age voice broke	0.8	1.2	1.8	0.4	-1.4	-1.2
Age when periods started (menarche)	0.8	2.0	3.2	-1.8	-1.4	-0.9
Qualifications: None of the above	0.8	1.6	3.3	-0.6	-1.8	-1.1
Length of working week for main job	0.8	0.9	1.7	1.3	-0.1	-1.1
Glaucoma (self-reported)	0.8	1.0	2.3	-0.2	-1.5	-0.8
Eye problems/disorders: None of the above	0.8	1.0	1.7	-1.3	0.7	0.9
Medication: Aspirin	0.8	1.0	2.3	-0.2	0.8	1.5
Hypertension (Self-reported)	0.8	2.2	4.6	1.3	0.7	2.1
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.1	0.5	1.5	0.7
Mood swings	0.8	1.4	2.0	0.7	1.4	1.3
Osteoporosis (self-reported)	0.8	1.0	2.2	-1.5	-0.4	-0.7
Medication: Lisinopril	0.8	1.0	1.5	-0.0	-1.2	-1.2
Alcohol drinker status: Never	0.8	1.0	2.2	1.5	0.0	-0.9
Alcohol drinker status: Previous	0.8	0.9	2.2	0.2	-0.7	-1.5
Allergy or Eczema	0.7	1.8	2.7	-1.6	-1.3	-1.0
Type 2 Diabetes (T2D) (2018)	0.7	1.4	3.1	-0.1	1.0	1.8
Chronic bronchitis/emphysema (father)	0.7	0.8	1.4	1.2	0.7	0.8
Medication for pain relief, constipation, heartburn	0.7	1.2	1.7	1.3	1.3	0.5
Average weekly red wine intake	0.7	1.1	2.3	1.5	0.9	-0.4
Mineral and other dietary supplements	0.7	0.9	1.3	1.1	0.3	1.1
Osteoarthritis (self-reported)	0.7	0.9	1.8	0.4	1.4	0.8
Medication: Gliclazide	0.7	0.7	2.0	1.4	0.3	-0.3
Illnesses of father: None of the above (group 1)	0.7	0.9	1.7	0.0	-1.0	-1.3
Commuting to job workplace: Public transport	0.7	0.9	1.8	0.1	0.9	1.3
Ever had prostate specific antigen (PSA) test	0.7	0.9	2.1	1.5	0.4	-0.6
Myopia	0.7	1.1	1.6	-1.3	-1.0	-0.7
Heart attack/myocardial infarction (self-reported)	0.7	0.9	1.5	-1.2	0.6	1.0
Intelligence (Savage-Jansen 2018)	0.6	1.8	3.5	-0.3	-1.9	-1.3
Mean Putamen Volume	0.6	0.7	1.9	0.1	-0.5	-1.4
Waist Hip Ratio (WHR)	0.6	2.7	6.2	-0.6	1.2	2.5
Supplements: Zinc	0.6	0.7	1.0	1.0	0.8	0.7
Hayfever, allergic rhinitis or eczema	0.6	1.3	1.7	-1.3	-1.2	-0.9
Illnesses of mother	0.6	0.7	0.9	0.9	0.9	0.7
Medication: Blood pressure	0.6	1.0	2.6	0.2	0.6	1.6
Age at last live birth	0.6	0.8	1.1	-1.0	-0.7	-0.9
Loneliness, isolation	0.6	0.9	1.6	0.1	1.3	1.0
Breast cancer (self-reported)	0.6	0.7	1.6	0.6	-0.2	-1.3
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.4	0.7	1.2	0.7
Risk taking	0.6	0.8	2.3	1.5	0.3	0.0
Blood Red Count	0.5	5.1	7.3	2.7	2.1	1.9
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.9	0.0	1.4	0.5
Medication: Levothyroxine sodium	0.5	0.8	1.3	0.6	1.1	0.8
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	1.6	0.4	-1.3	-0.3
Fluid intelligence score	0.5	1.0	1.9	-0.1	-1.4	-1.1
Noisy workplace	0.5	0.7	1.8	-1.4	0.4	0.0
Mouth/teeth dental problems: Dentures	0.5	0.8	1.1	0.9	1.0	0.7
Headache pain in last month	0.5	0.9	1.7	0.2	0.9	1.3
Health satisfaction	0.5	0.7	1.2	-0.5	-1.1	-0.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	0.9	0.3	-0.8	-0.9
Medication: Seretide 50 evohaler	0.5	0.6	1.1	-0.5	-0.6	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	0.9	-0.8	-0.9	-0.6
Alcohol intake frequency.	0.5	1.2	1.6	1.3	1.1	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.5	0.8	-0.5	0.8	0.9
Illnesses of father: Heart disease	0.5	0.7	1.7	-1.3	0.7	-0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.4	0.7	1.2	0.2
Medication: Aspirin	0.5	0.6	1.5	-0.1	0.6	1.2
Mother’s age at death	0.5	0.6	1.1	1.0	0.8	0.3
Medication: Blood pressure	0.5	1.0	1.8	1.0	0.4	1.3
Average weekly beer plus cider intake	0.5	0.7	1.5	-0.7	1.2	0.3
Age started oral contraceptive pill	0.5	0.6	0.9	-1.0	0.0	0.9
Cholesterol lowering medication	0.5	0.8	1.2	0.3	1.1	1.0
Basal cell carcinoma (self-reported)	0.5	0.5	1.2	-0.2	0.6	1.1
Depression (Nagel 2018)	0.4	0.5	0.9	-0.9	-0.2	-0.9
Bipolar Disorder (2011)	0.4	0.3	0.9	0.4	0.9	0.0
LDL Cholesterol	0.4	0.6	1.6	0.5	-0.2	-1.2
BMI	0.4	2.4	6.7	2.6	0.7	0.3
Relative age of first facial hair	0.4	0.9	1.7	1.3	-0.6	-0.8
Systolic blood pressure, automated reading	0.4	1.1	2.9	-0.0	-1.7	-0.6
Severe depression (siblings)	0.4	0.5	0.8	0.4	0.9	0.6
Hand grip strength (right)	0.4	1.1	2.3	-1.5	-0.3	-1.0
Multivitamins +/- minerals	0.4	0.6	1.5	0.0	-0.4	-1.2
Hair/balding pattern: Pattern 2	0.4	0.4	1.3	1.1	-0.2	-0.2
Medication: Ramipril	0.4	0.5	1.0	-0.7	-1.0	0.0
Illnesses of siblings	0.4	0.6	0.9	1.0	0.8	-0.6
Hip circumference	0.4	1.8	4.4	2.1	1.0	0.3
Alcohol intake versus 10 years previously	0.4	0.6	1.0	0.2	0.9	1.0
Pulse rate	0.4	0.7	1.8	-0.0	-1.4	-0.3
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.5	-0.8	-0.6	-1.2
Exposure to tobacco smoke at home	0.4	0.4	1.0	0.4	-0.4	-1.0
Medication: Amlodipine	0.4	0.6	1.8	1.3	-0.0	0.0
Birth weight	0.4	0.9	1.6	1.2	1.1	0.1
High blood pressure (siblings)	0.4	0.6	1.6	-0.3	-0.1	1.3
Body fat percentage	0.4	1.7	3.6	1.9	1.0	0.8
Leg fat percentage (right)	0.4	1.6	2.0	1.4	1.3	1.0
Exposure to tobacco smoke outside home	0.4	0.5	1.0	1.0	-0.0	-0.7
Number of children fathered	0.4	0.5	1.2	0.5	1.1	0.2
Neck or shoulder pain in last month	0.4	0.6	1.5	-0.5	0.0	1.2
Smoking status: Previous	0.4	0.7	1.2	-0.7	0.6	1.1
Qualifications: nursing, teaching	0.4	0.6	1.1	1.0	0.7	-0.5
Average weekly champagne plus white wine intake	0.4	0.6	0.7	-0.6	-0.8	-0.8
Medication: Bendroflumethiazide	0.4	0.7	1.0	0.5	-1.0	0.8
Number of operations (self-reported)	0.4	0.5	1.4	1.2	-0.1	0.5
Heart disease (siblings)	0.4	0.5	1.2	-0.4	-1.1	-0.5
Pack years of smoking	0.4	0.6	0.9	-0.8	-0.4	-0.9
Worry (Nagel 2018)	0.3	0.5	0.7	-0.7	0.8	0.7
Alzheimer’s Disease (including proxy)	0.3	0.4	0.7	-0.8	-0.5	-0.4
Crohns Disease (2017)	0.3	0.6	1.6	1.3	0.1	0.3
Body Mass Index (BMI) (2010)	0.3	0.4	0.7	-0.4	0.6	0.8
Coronary Artery Disease (CAD)	0.3	0.4	0.7	-0.9	-0.5	-0.4
Crohns Disease (2012)	0.3	0.5	1.2	0.2	0.4	1.1
Primary Biliary Cirrhosis	0.3	0.4	0.8	0.1	0.6	0.9
Average weekly spirits intake	0.3	0.4	0.8	-0.6	-0.9	0.0
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.5	-0.0	-0.7	-0.7
Trunk fat percentage	0.3	1.3	3.5	1.9	0.6	0.3
Average weekly fortified wine intake	0.3	0.3	0.5	-0.2	-0.7	0.6
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.5	0.7	0.3	0.7
Body mass index (BMI)	0.3	1.2	2.7	1.6	0.8	0.3
Trunk fat mass	0.3	1.2	3.1	1.8	0.8	0.2
Waist circumference	0.3	1.1	1.8	1.3	0.9	0.8
Alcohol usually taken with meals	0.3	0.4	0.9	0.4	-1.0	-0.5
Had other major operations	0.3	0.3	0.9	1.0	-0.3	-0.1
Happiness	0.3	0.4	0.8	0.2	-0.5	-0.9
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.6	0.1	0.8	0.7
Comparative body size at age 10	0.3	0.9	1.9	0.8	1.4	0.4
Medication: Omeprazole	0.3	0.3	0.7	0.1	-0.5	-0.9
Whole body fat mass	0.3	1.1	2.4	1.5	0.9	0.3
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.8	0.9	0.5	-0.4
Knee pain experienced in last month	0.3	0.4	0.7	-0.5	-0.6	-0.8
Illnesses of siblings: Diabetes	0.3	0.4	0.8	-0.9	0.2	0.5
Long-standing illness, disability or infirmity	0.3	0.4	0.6	0.0	0.7	0.8
Friendships satisfaction	0.3	0.4	0.7	0.1	0.7	0.8
Commuting to job workplace: Walk	0.3	0.3	0.8	-0.9	-0.1	0.3
Miserableness	0.3	0.6	0.8	-0.9	0.9	0.3
Guilty feelings	0.3	0.4	0.8	-0.3	0.5	0.9
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.5	-0.4	-0.7	-0.7
Leg fat percentage (left)	0.3	1.2	1.8	1.4	1.1	0.8
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.6	-0.4	-0.7	-0.6
Supplements: Calcium	0.3	0.4	0.6	0.5	0.8	-0.5
Depressed Affect (Nagel 2018)	0.2	0.5	1.5	0.2	1.2	0.1
Alzheimer’s Disease (in mother)	0.2	0.2	0.5	-0.2	-0.2	-0.7
Reaction Time	0.2	0.5	1.1	-0.2	-1.1	-0.5
Prostate Cancer	0.2	0.3	0.8	0.9	0.1	0.2
Age at First Birth	0.2	0.3	0.5	-0.7	-0.6	0.1
HDL Cholesterol	0.2	0.3	0.5	0.7	-0.4	-0.6
Rheumatoid Arthritis	0.2	0.3	0.4	0.4	0.6	0.6
Blood Eosinophil Count	0.2	1.9	4.2	2.1	1.1	0.5
Blood Platelet Count	0.2	2.1	4.2	0.8	1.2	2.1
Hair Pigment	0.2	4.9	8.9	3.0	2.2	1.1
Medication for hormone replacement therapy	0.2	0.2	0.5	-0.1	0.2	0.7
Vitamin and mineral supplements	0.2	0.2	0.7	0.1	-0.2	0.8
Diabetes (mother)	0.2	0.3	0.8	-0.9	0.3	-0.2
Pack years adult smoking proportion	0.2	0.4	0.5	-0.7	-0.2	-0.7
Townsend deprivation index at recruitment	0.2	0.3	0.4	0.4	-0.6	-0.5
Fed-up feelings	0.2	0.3	0.6	0.5	0.8	0.4
Qualifications: CSEs or equivalent	0.2	0.3	0.7	-0.1	0.8	0.4
Past tobacco smoking	0.2	0.3	0.6	-0.2	-0.6	-0.7
Had menopause	0.2	0.3	0.5	-0.7	0.6	0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.3	0.3	0.6	0.5
Financial difficulties in last 2 years	0.2	0.3	0.5	-0.7	0.5	0.4
Pain all over the body in last month	0.2	0.2	0.5	0.4	0.7	0.1
Diabetes (self-reported)	0.2	0.2	0.7	0.8	0.1	0.2
Weight	0.2	1.2	2.8	1.7	0.8	0.3
Arm fat percentage (right)	0.2	0.9	2.1	1.4	0.6	0.6
Time employed in main current job	0.2	0.3	0.3	-0.6	-0.5	-0.4
Father’s age at death	0.2	0.3	0.5	-0.7	0.6	0.2
Worrier / anxious feelings	0.2	0.4	0.9	-0.1	0.9	0.6
Falls in the last year	0.2	0.3	0.5	0.7	-0.4	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.5	0.7	0.4	-0.3
Asthma	0.2	0.3	0.7	-0.3	-0.8	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.6	0.5	1.3	0.2
Arm fat mass (right)	0.2	0.8	1.8	1.3	0.8	0.5
Pulse wave reflection index	0.2	0.2	0.3	-0.3	0.6	-0.6
Age at first live birth	0.2	0.4	0.6	-0.7	-0.7	-0.3
Emphysema/chronic bronchitis	0.2	0.2	0.4	0.3	-0.4	-0.6
Medication: Ibuprofen	0.2	0.2	0.3	-0.6	-0.4	-0.5
Leg fat mass (right)	0.2	0.8	1.4	1.2	0.9	0.5
Pulse rate, automated reading	0.2	0.6	1.0	-0.2	-1.0	0.8
Leg pain on walking	0.2	0.2	0.7	0.8	-0.2	0.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.6	-0.4	-0.7	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.6	-0.8	-0.1	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.0	1.0	-0.3	0.1
Arm fat percentage (left)	0.2	0.9	2.2	1.5	0.5	0.4
Ever had bowel cancer screening	0.2	0.3	0.8	-0.9	0.2	-0.2
Ever taken oral contraceptive pill	0.2	0.3	0.5	0.5	0.2	0.7
Hearing aid user	0.2	0.3	0.4	0.6	-0.1	0.6
Diastolic blood pressure, automated reading	0.2	0.5	0.8	0.7	-0.9	0.3
Pain experienced in last month	0.2	0.4	0.6	-0.0	-0.7	-0.8
Leg fat mass (left)	0.2	0.9	1.6	1.3	0.9	0.4
Bipolar Disorder or Schizophrenia	0.1	0.1	0.2	0.4	0.1	-0.5
Schizophrenia (2018)	0.1	0.2	0.5	-0.7	-0.2	0.3
Alzheimer’s Disease (in father)	0.1	0.2	0.2	-0.3	-0.4	0.4
Irritable Bowel Disease (IBD)	0.1	0.2	0.3	0.4	-0.6	-0.3
Major Depression (MDD)	0.1	0.1	0.2	0.0	0.4	0.1
Schizophrenia (2014)	0.1	0.1	0.4	-0.1	0.3	0.6
Ulcerative Colitis	0.1	0.2	0.4	0.2	-0.7	-0.3
Heel T-Score	0.1	1.1	2.2	-0.0	1.0	1.5
Height	0.1	1.6	3.9	-0.0	-0.9	-2.0
Systolic Blood Pressure	0.1	0.5	1.0	0.6	-1.0	0.3
Lung FEV1/FVC ratio	0.1	0.6	1.0	-0.6	1.0	0.7
Hand grip strength (left)	0.1	0.3	0.5	-0.6	-0.0	-0.7
Number of treatments/medications taken	0.1	0.1	0.2	-0.4	-0.2	0.3
Impedance of leg (right)	0.1	0.3	0.7	-0.3	0.4	0.8
Leg fat-free mass (left)	0.1	0.3	0.5	0.7	0.1	-0.5
Maternal smoking around birth	0.1	0.1	0.2	0.4	-0.0	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.5	0.7	0.3	0.1
Taking other prescription medications	0.1	0.2	0.6	-0.1	0.3	0.7
Medication: Atenolol	0.1	0.1	0.2	-0.2	0.3	0.4
Leg predicted mass (left)	0.1	0.3	0.5	0.7	0.1	-0.6
Forced vital capacity (FVC)	0.1	0.3	0.5	0.1	0.5	-0.7
Impedance of arm (right)	0.1	0.2	0.7	0.0	-0.2	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.3	-0.5	-0.2	-0.0
Hair/balding pattern: Pattern 3	0.1	0.1	0.3	0.3	0.0	-0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.6	-0.3	0.8	-0.2
Impedance of arm (left)	0.1	0.3	0.8	0.2	-0.2	0.9
Hair/balding pattern: Pattern 4	0.1	0.3	0.4	-0.6	0.7	0.2
Birth weight of first child	0.1	0.1	0.3	0.2	0.5	-0.0
Peak expiratory flow (PEF)	0.1	0.3	0.4	-0.6	0.7	0.0
Medication: Paracetamol	0.1	0.2	0.7	-0.1	-0.0	0.8
Forced vital capacity (FVC), Best measure	0.1	0.4	0.5	0.7	0.6	-0.5
Shortness of breath walking on level ground	0.1	0.1	0.2	0.4	-0.3	-0.3
Migraine (self-reported)	0.1	0.2	0.4	-0.1	-0.3	0.6
Mean time to correctly identify matches	0.1	0.2	0.3	0.6	-0.3	0.3
Comparative height size at age 10	0.1	0.3	0.4	-0.6	-0.3	-0.6
Leg fat-free mass (right)	0.1	0.3	0.6	0.5	-0.1	-0.7
Asthma (self-reported)	0.1	0.3	0.6	-0.4	-0.8	-0.3
Leg predicted mass (right)	0.1	0.3	0.6	0.5	-0.1	-0.8
Arm fat mass (left)	0.1	0.6	1.4	1.2	0.5	0.2
Number of self-reported non-cancer illnesses	0.1	0.2	0.4	-0.2	-0.0	0.7
Medication: Paracetamol	0.1	0.1	0.2	-0.4	-0.3	0.4
Medication: Atorvastatin	0.1	0.1	0.3	-0.1	-0.5	0.3
Ever smoked	0.1	0.3	0.4	0.6	0.5	0.3
Ever depressed for a whole week	0.1	0.1	0.1	0.4	-0.3	-0.3
Commuting to job workplace: Cycle	0.1	0.2	0.4	-0.7	-0.1	0.3
Impedance of whole body	0.1	0.3	0.8	-0.1	-0.0	0.9
Ulcerative Colitis (UC)	0.0	0.1	0.2	0.1	-0.4	-0.2
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.2	0.4	-0.3	-0.1
Fasting Glucose	0.0	0.0	0.0	-0.0	0.0	0.1
Lupus	0.0	0.0	0.0	-0.1	-0.0	-0.0
Smoking Status	0.0	0.1	0.1	-0.1	-0.4	-0.3
Respiratory disease	0.0	0.1	0.1	0.3	-0.3	0.2
Lung FVC	0.0	0.2	0.6	-0.0	0.0	-0.7
Tanning	0.0	0.4	1.2	1.1	-0.0	-0.3
Medication: Metformin	0.0	0.0	0.1	0.3	0.1	-0.1
Serious illness, injury or assault to yourself	0.0	0.0	0.0	0.0	0.1	-0.2
Sitting height	0.0	0.2	0.4	0.4	-0.4	-0.6
Impedance of leg (left)	0.0	0.2	0.4	-0.5	0.1	0.6
Trunk fat-free mass	0.0	0.2	0.6	0.0	-0.2	-0.8
Trunk predicted mass	0.0	0.2	0.7	-0.1	-0.3	-0.8
Standing height	0.0	0.2	0.4	0.6	0.4	-0.0
Arm fat-free mass (right)	0.0	0.1	0.2	0.2	0.5	-0.1
Qualifications: College or University degree	0.0	0.1	0.2	0.4	0.3	0.3
Heart disease (mother)	0.0	0.0	0.1	-0.1	0.3	0.1
Arm predicted mass (right)	0.0	0.2	0.4	0.3	0.7	-0.1
Overall health rating	0.0	0.1	0.1	-0.3	0.0	-0.3
Whole body fat-free mass	0.0	0.2	0.4	0.3	-0.0	-0.7
Diabetes diagnosed by doctor	0.0	0.0	0.0	0.2	-0.2	0.2
Eye problems/disorders: Cataract	0.0	0.0	0.0	-0.2	-0.1	0.0
Back pain experienced in last month	0.0	0.0	0.0	0.1	-0.0	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.1	0.2	0.3	0.2
Whole body water mass	0.0	0.2	0.5	0.3	-0.0	-0.7
Illnesses of father: High blood pressure	0.0	0.0	0.1	-0.2	0.2	0.2
Basal metabolic rate	0.0	0.2	0.4	0.6	0.2	-0.5
Arm fat-free mass (left)	0.0	0.1	0.3	0.2	0.6	0.1
Arm predicted mass (left)	0.0	0.1	0.3	-0.0	0.0	-0.5

Hub : Genes

MARVELD2

Models

Trait associations